All / All / ATPlike

Total number of chains: 686
Active chains: 178
Total number of genes: 132
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 418 60.9% 8QCGA
DFGin BLBplus 92 13.4% 2SRCA
DFGin None 47 6.9% 5I4NA
DFGin BLBtrans 35 5.1% 2GS7B
DFGinter None 30 4.4% 9D5IA
DFGin ABAminus 28 4.1% 7N8TA
DFGin BLBminus 13 1.9% 4LGDA
None None 11 1.6% 7F2XA
DFGin BLAplus 7 1.0% 6PNXB
DFGout None 5 0.7% 6VPHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC AKT1 AKT1_HUMAN 4EKKA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 4EKKB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 1O6KA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 479 0 TPO309 S474D RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 1O6LA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 477 0 TPO309 None RAC-beta serine/threonine-protein kinase
AGC CDC42BPB MRCKB_HUMAN 4UAKA 1.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta
AGC GRK4 GRK4_HUMAN 4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4
AGC GRK4 GRK4_HUMAN 4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4
AGC GRK5 GRK5_HUMAN 4TNDA 1.802 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 543 0 None None G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9CKRA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9CKSA 3.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK6 GRK6_HUMAN 2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
AGC PDPK1 PDPK1_HUMAN 1H1WA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 71 - 359 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 2BIYA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 72 - 359 0 None S241A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3HRCA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 4RRVA 1.412 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5ACKA 1.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 73 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPC 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPD 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 4CT2A 1.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5MRDA 1.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C 3-phosphoinositide-dependent protein kinase 1
AGC PKN2 PKN2_HUMAN 4CRSA 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 646 - 984 0 SEP755,TPO816,TPO958 None Serine/threonine-protein kinase N2
AGC PRKACA KAPCA_HUMAN 4WB8A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB5A 1.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6NO7E 3.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6NO7G 3.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB7A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB7B 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6BYRA 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6BYRC 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9EDCA 4.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9EDDA 6.3 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9EDEA 5.9 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP11,SEP140,TPO198 L206R cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB6B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 9 - 351 0 SEP11,TPO198,SEP339 L206R cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKCB KPCB_HUMAN 8SE1A 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE1B 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE2B 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCI KPCI_HUMAN 8R3YI 3.68 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 585 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 3A8WA 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 3A8WB 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LIHA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 248 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LIHB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LI9A 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 248 - 589 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LI1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 589 0 TPO412,SEP484,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 9EJMB 3.33 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKG1 KGP1_HUMAN 6BG2A 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 336 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2B 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 346 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2C 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2D 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 344 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7LV3A 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 57 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7LV3B 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 58 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC ROCK1 ROCK1_HUMAN 2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
AGC RPS6KA1-1 KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOA 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 45 - 348 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOE 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOI 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_onnn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOK 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOC 2.75 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 46 - 347 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOG 2.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aanni APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA6-1 KS6A6_HUMAN 6G76B 3.0 Inactive DFGinter‑None none-none out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6
AGC RPS6KA6-1 KS6A6_HUMAN 6G78A 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaoii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6
AGC RPS6KA6-1 KS6A6_HUMAN 6G78B 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6
AGC SGK1 SGK1_HUMAN 2R5TA 1.9 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiio APEdist_oooo ANP ATPlike 82 - 378 0 None S74A,S78A,S397A,S401A Serine/threonine-protein kinase Sgk1
AGC STK38 STK38_HUMAN 6BXIA 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 82 - 414 0 None None Serine/threonine-protein kinase 38
AGC STK38 STK38_HUMAN 6BXIB 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 83 - 414 0 None None Serine/threonine-protein kinase 38
CAMK AURKA AURKA_HUMAN 4C3PD 2.69 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nooo ACP ATPlike 125 - 390 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWA 2.7 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWB 2.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 507 - 390 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWC 2.7 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 4BN1A 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 126 - 388 0 TPO287,TPO288 V174M Aurora kinase A
CAMK AURKA AURKA_HUMAN 1MQ4A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 126 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DNRA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 126 - 390 0 TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DT3A 2.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ATP ATPlike 127 - 390 0 TPO287 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 1OL5A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 123 - 388 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 1OL7A 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 127 - 390 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5G15A 2.06 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 126 - 390 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 2DWBA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 126 - 389 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6CPFA 2.3 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 128 - 392 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6VPGA 2.64 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DRDA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ATP ATPlike 127 - 390 0 None T287A Aurora kinase A
CAMK AURKA AURKA_HUMAN 4DEEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 124 - 394 0 None T287D Aurora kinase A
CAMK AURKA AURKA_HUMAN 6VPIA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 104 - 389 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5LXMA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 4CEGA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 127 - 391 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5G1XA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 1OL6A 3.0 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 128 - 388 0 None D274N Aurora kinase A
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 4C3PA 2.69 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaooi APEdist_oooo ACP ATPlike 125 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 2C6DA 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ANP ATPlike 126 - 390 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5ODTA 2.021 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 392 0 None D274N,C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 4C3RA 2.79 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 127 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6C83B 2.55 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ACP ATPlike 127 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5L8JA 1.68 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 126 - 391 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5L8KA 1.79 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5L8LA 1.67 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iooo ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8PR7A 2.76 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 124 - 389 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 6VPJA 2.1 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 104 - 389 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6VPHA 2.14 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oioo ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6C83A 2.55 Inactive None‑None out-none none-out nonTYR APEdihe_aaooi APEdist_nnno ACP ATPlike 127 - 389 0 None None Aurora kinase A
CAMK CAMK1 KCC1A_HUMAN 4FG7A 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ATP ATPlike 9 - 277 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK1 KCC1A_HUMAN 4FG9A 2.4 Inactive DFGinter‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 10 - 314 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK1 KCC1A_HUMAN 4FG9B 2.4 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaini APEdist_nnno ATP ATPlike 14 - 314 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK1 KCC1A_HUMAN 4FG8A 2.2 Inactive None‑None out-none none-out nonTYR APEdihe_aanno APEdist_nnnn ATP ATPlike 10 - 299 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK1 KCC1A_HUMAN 4FG8B 2.2 Inactive None‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnno ATP ATPlike 14 - 299 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK2A KCC2A_HUMAN 7UJSA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UIRA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UIRB 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UJPA 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UJPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UJTA 2.1 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CASK CSKP_HUMAN 3MFRA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3MFSA 2.1 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3MFUA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 9M6GA 1.7 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 312 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 9M5YA 1.8 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 312 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0HA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0HB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK
CAMK CHEK1 CHK1_HUMAN 7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 5OOPA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
CAMK CHEK2 CHK2_HUMAN 2CN5A 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 209 - 504 0 None None Serine/threonine-protein kinase Chk2
CAMK DAPK1 DAPK1_HUMAN 2W4JA 1.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTB 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTC 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 5 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTD 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 1IG1A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 294 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 1JKKA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 293 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 1JKLA 1.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 294 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3EH9A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3EHAA 1.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3F5GA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3F5UA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 2W4KA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3DFCB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23K Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3GU4A 1.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3GU5A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3GU6A 1.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3GU7A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 2XUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None E182A Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTA 2.65 Inactive DFGin‑BLBminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK DCLK1 DCLK1_HUMAN 5JZJA 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 374 - 648 0 None None Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZJB 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 382 - 648 0 None None Serine/threonine-protein kinase DCLK1
CAMK MAPKAPK2 MAPK2_HUMAN 1NY3A 3.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 46 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MELK MELK_HUMAN 4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK PASK PASK_HUMAN 3DLSA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSE 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSF 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PHKG1 PHKG1_HUMAN 8Z5RC 3.52 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
CAMK PHKG1 PHKG1_HUMAN 8Z5TC 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
CAMK PHKG1 PHKG1_HUMAN 8Z5TG 3.74 Inactive DFGin‑BLAminus out-none out-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
CAMK PHKG1 PHKG1_HUMAN 8Z5TK 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
CAMK PHKG1 PHKG1_HUMAN 8Z5TO 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
CAMK PIM1 PIM1_HUMAN 1YXTA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 306 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUA 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUB 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUC 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 34 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUD 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1XR1A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 308 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 3A99A 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 2BZKB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1
CAMK PLK1 PLK1_HUMAN 8X72A 2.2 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiio APEdist_ioio ANP ATPlike 37 - 330 0 None None Serine/threonine-protein kinase PLK1
CAMK PLK1 PLK1_HUMAN 2OU7A 2.4 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiio APEdist_ioio ANP ATPlike 37 - 328 0 None T210V Serine/threonine-protein kinase PLK1
CAMK PLK4 PLK4_HUMAN 3COKA 2.25 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 266 0 None None Serine/threonine-protein kinase PLK4
CAMK PLK4 PLK4_HUMAN 3COKB 2.25 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 266 0 None None Serine/threonine-protein kinase PLK4
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5B 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK STK11 STK11_HUMAN 2WTKC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 47 - 342 0 None D194A Serine/threonine-protein kinase STK11
CAMK STK11 STK11_HUMAN 2WTKF 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 45 - 340 0 None D194A Serine/threonine-protein kinase STK11
CAMK STK17B ST17B_HUMAN 6QF4A 2.495 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nioo ADP ATPlike 18 - 308 0 None None Serine/threonine-protein kinase 17B
CAMK STK17B ST17B_HUMAN 7Q7CA 2.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B
CAMK STK17B ST17B_HUMAN 7Q7DA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B
CAMK STK17B ST17B_HUMAN 7Q7EA 2.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B
CK1 CSNK1D KC1D_HUMAN 6RU6A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU6B 2.05 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7FA 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7FB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7GA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo AMP ATPlike 8 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7GB 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi AMP ATPlike 7 - 293 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7HA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7HB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 TTBK1 TTBK1_HUMAN 4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK2 TTBK2_HUMAN 6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
CK1 VRK1 VRK1_HUMAN 6AC9A 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 342 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6AC9B 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6AC9C 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6AC9D 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CMGC CDK1 CDK1_HUMAN 9SKQA 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiii ANP ATPlike 3 - 288 0 TPO161 None Cyclin-dependent kinase 1
CMGC CDK11B CD11B_HUMAN 9I9IK 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 440 - 740 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK12 CDK12_HUMAN 4CXAA 3.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 718 - 1050 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 4NSTA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 716 - 1046 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 4NSTC 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 717 - 1045 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK13 CDK13_HUMAN 5EFQA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 695 - 1025 0 TPO871 None Cyclin-dependent kinase 13
CMGC CDK13 CDK13_HUMAN 5EFQC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 697 - 1031 0 TPO871 None Cyclin-dependent kinase 13
CMGC CDK2 CDK2_HUMAN 4EOOA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 Q131E Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOOC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 Q131E Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOMA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 H84S,Q85M,Q131E Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOMC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 H84S,Q85M,Q131E Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4I3ZA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4I3ZC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHRA 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHRC 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHWA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHWC 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1FINA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1FINC 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1FQ1B 3.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_oioo ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1JSTA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1JSTC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CJMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 292 0 PTR15,TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CJMC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 297 0 PTR15,TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4II5A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4II5C 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GY3A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GY3C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1QMZA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1QMZC 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCHC 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCIA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCIC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9I9JK 3.1 Inactive DFGin‑BLAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 6 - 284 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9I9KK 2.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 2 - 292 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9QCVK 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 1 - 292 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOQA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOQC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOJA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 H84S,Q85M,K89D Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EOJC 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 H84S,Q85M,K89D Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1HCKA 1.9 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FP5A 1.7 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1B38A 2.0 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1B39A 2.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK7 CDK7_HUMAN 6XBZJ 2.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 312 0 SEP164 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R99A 1.81 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 10 - 311 0 None W132R,S164D,T170E Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8P6YJ 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9I9IJ 3.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 12 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9I9JJ 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ADP ATPlike 11 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9I9KJ 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ADP ATPlike 10 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9QCVJ 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 10 - 346 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9SKQJ 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 9 - 346 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 9HIYJ 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None D97N Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 1UA2A 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 1UA2B 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 1UA2C 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 1UA2D 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R9BA 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 1 - 311 0 None S164D,T170E Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R9BB 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 3 - 310 0 None S164D,T170E Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R9BC 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo ANP ATPlike 8 - 311 0 None S164D,T170E Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R9BD 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ANP ATPlike 9 - 311 0 None S164D,T170E Cyclin-dependent kinase 7
CMGC CDK9 CDK9_HUMAN 3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 3JUHA 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3JUHB 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6Z19B 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3NSZA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 4NH1A 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ACP ATPlike 3 - 332 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 4NH1B 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ACP ATPlike 2 - 333 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 1PJKA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 332 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 2PVRA 1.605 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3WOWA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 335 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 1JWHA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 337 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3U87A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3U87B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5OQUB 2.324 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5ORKB 2.143 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 326 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7QUXA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 SEP2 None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6YZHA 1.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CU6A 1.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QCGA 1.04 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 330 0 None C336S Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha'
CMGC DYRK1A DYR1A_HUMAN 7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4OB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC GSK3B GSK3B_HUMAN 4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4NM0A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 8XN6B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 26 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC MAPK1 MK01_HUMAN 4H3QA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo ANP ATPlike 9 - 360 0 None R77A,C161S,I255G,E314A Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5A 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5B 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5C 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ5D 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 2Y9QA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4FMQA 2.098 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4NIFB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 360 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4NIFE 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 360 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 8PSRA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 1 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 3TEIA 2.404 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 358 0 None R77A,E314A Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4H3PA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4H3PD 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1
CMGC MAPK10 MK10_HUMAN 8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK12 MK12_HUMAN 1CM8A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 1CM8B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12
CMGC MAPK7 MK07_HUMAN 4IC7A 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 46 - 400 0 None None Mitogen-activated protein kinase 7
CMGC MAPK7 MK07_HUMAN 4IC7D 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 47 - 399 0 None None Mitogen-activated protein kinase 7
CMGC MAPK8 MK08_HUMAN 6ZR5A 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 3 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 6ZR5B 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 4 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2XRWA 1.33 Inactive DFGin‑ABAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2XS0A 2.6 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ANP ATPlike 6 - 365 0 None T183V,Y185F Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 9FT9A 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 7 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9B 2.34 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK9 MK09_HUMAN 7N8TA 1.69 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iioo AMP ATPlike 10 - 364 0 None None Mitogen-activated protein kinase 9
CMGC PRP4K PRP4K_HUMAN 4IFCA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
CMGC PRP4K PRP4K_HUMAN 4IFCB 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
CMGC PRP4K PRP4K_HUMAN 4IIRA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
CMGC PRP4K PRP4K_HUMAN 4IIRB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
CMGC SRPK1 SRPK1_HUMAN 3BEGA 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 69 - 655 0 None None SRSF protein kinase 1
CMGC SRPK1 SRPK1_HUMAN 1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1
NEK NEK2 NEK2_HUMAN 2W5BA 2.4 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo AGS ATPlike 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2W5AA 1.55 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ADP ATPlike 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK7 NEK7_HUMAN 9NFQC 3.25 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 2WQNA 2.3 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 21 - 300 0 None None Serine/threonine-protein kinase Nek7
OTHER BUB1 BUB1_HUMAN 4QPMA 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 4QPMB 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1081 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 4R8QA 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iooo ADP ATPlike 736 - 1083 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 5DMZA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 5DMZB 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 256 - 544 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn ADP ATPlike 255 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 257 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER TLK2 TLK2_HUMAN 5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCPB 4.1 Pseudo DFGin‑BLBtrans out-none out-out nonTYR APEdihe_aaoao APEdist_oooo ATP ATPlike 503 - 841 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCSA 4.4 Pseudo DFGin‑None out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 503 - 1055 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCSB 4.4 Pseudo None‑None out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 505 - 1055 0 None None Atrial natriuretic peptide receptor 1
STE MAP2K1 MP2K1_HUMAN 3EQDA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQIA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5YT3C 2.9 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6U2GA 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6V2WB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5YT3B 2.9 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5YT3D 2.9 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 39 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5YT3A 2.9 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ANP ATPlike 39 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7F2XA 2.007 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ANP ATPlike 45 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3W8QA 2.2 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo AGS ATPlike 39 - 382 0 None T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K4 MP2K4_HUMAN 3ALNA 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 83 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 3ALNB 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 84 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 3ALOA 2.6 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoao APEdist_oooo ANP ATPlike 95 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 3ALNC 2.3 Inactive None‑None na-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 100 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP3K14 M3K14_HUMAN 4DN5A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_noii AGS ATPlike 332 - 675 0 None S549D Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 4DN5B 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_noii AGS ATPlike 333 - 675 0 None S549D Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 8YHWA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 8YHWB 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 8YHWC 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP4K1 M4K1_HUMAN 6CQDA 2.12 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 2 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 6CQDB 2.12 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 4 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K4 M4K4_HUMAN 4U40A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE OXSR1 OXSR1_HUMAN 3DAKA 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 6 - 295 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 3DAKB 2.25 Inactive DFGin‑BLBtrans out-out out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 6 - 295 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 3DAKC 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 7 - 295 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 3DAKD 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ANP ATPlike 7 - 295 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 2VWIB 2.15 Inactive DFGin‑BLBtrans out-out out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 9 - 292 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 2VWIC 2.15 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo ANP ATPlike 9 - 292 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 2VWID 2.15 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 6 - 298 0 None None Serine/threonine-protein kinase OSR1
STE OXSR1 OXSR1_HUMAN 2VWIA 2.15 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaioi APEdist_nnno ANP ATPlike 13 - 292 0 None None Serine/threonine-protein kinase OSR1
STE PAK1 PAK1_HUMAN 3Q53A 2.09 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 250 - 541 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 3Q4ZA 1.887 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 251 - 545 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1
STE PAK3 PAK3_HUMAN 6FD3A 1.52 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 261 - 556 0 None A537D Serine/threonine-protein kinase PAK 3
STE PAK4 PAK4_HUMAN 4XBRA 2.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 177 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIFA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 296 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIFB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 297 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIGA 3.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 298 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4JDIA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 5UPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 588 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIEA 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 49 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIEB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 49 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7S46A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7S47A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIGB 3.01 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 298 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE STK24 STK24_HUMAN 3A7HA 1.96 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 310 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 3A7HB 1.96 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 17 - 310 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 3A7JA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 311 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 4QMLA 1.882 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 310 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 4O27B 3.185 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 30 - 309 0 None T190E Serine/threonine-protein kinase 24
STE STK3 STK3_HUMAN 6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3
STE STRADA STRAA_HUMAN 2WTKB 2.65 Pseudo DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 61 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 2WTKE 2.65 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 3GNIB 2.35 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ATP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 8VSUB 2.86 Pseudo DFGin‑None out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ADP ATPlike 60 - 401 0 None None STE20-related kinase adapter protein alpha
STE TAOK3 TAOK3_HUMAN 6BDNA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 8 - 314 0 None R2A,K3A Serine/threonine-protein kinase TAO3
STE TNIK TNIK_HUMAN 7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
TKL ACVR1 ACVR1_HUMAN 6UNQA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 206 - 496 0 None K493A Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNRA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 208 - 496 0 None None Activin receptor type-1
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2
TKL BRAF BRAF_HUMAN 9AXXB 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYPC 3.29 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 363 - 733 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK4 IRAK4_HUMAN 2OIDA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDB 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGFB 2.61 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 164 - 460 0 None None Interleukin-1 receptor-associated kinase 4
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHTA 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHTB 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHWA 3.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 540 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LI4A 3.1 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO2E 4.13 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO8C 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO8E 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9F 3.48 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH5A 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH5C 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LI3A 3.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9E 3.48 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH4A 4.1 Inactive None‑None out-none out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RIPK2 RIPK2_HUMAN 5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TYR ABL1 ABL1_HUMAN 2G2IA 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 229 - 502 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2IB 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 232 - 500 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2FB 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 234 - 502 0 None H396P Tyrosine-protein kinase ABL1
TYR ALK ALK_HUMAN 3LCTA 2.1 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor
TYR EGFR EGFR_HUMAN 3VJNA 2.34 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8DSWA 2.39 Inactive DFGin‑BLAminus none-none in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3VJOA 2.64 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1019 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 698 - 1015 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1014 0 None I706Q Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DA 2.4 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 700 - 1021 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB 2.4 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1020 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNB 1.76 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4A 2.2 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4A 2.99 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 698 - 1022 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMA 2.192 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO4B 1.621 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS7A 2.6 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 703 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS7B 2.6 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1016 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8A 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8B 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 701 - 1007 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8C 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 699 - 1007 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8D 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 701 - 1010 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNOA 1.55 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 700 - 1015 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNNB 1.9 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 700 - 1014 0 None I706Q Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWB 3.1 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWD 3.1 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXB 3.1 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD 3.1 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYB 2.981 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD 2.981 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 5I9VA 1.458 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AGS ATPlike 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 1MQBA 2.3 Inactive DFGin‑BLAminus in-out none-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 605 - 887 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 1MQBB 2.3 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 602 - 883 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAB 1.75 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9WA 1.359 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCA 2.3 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai ACP ATPlike 590 - 976 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCB 2.3 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAA 1.75 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 976 0 None None Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 2QOCA 1.25 Inactive DFGin‑BLAminus in-out in-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 613 - 906 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 3FXXA 1.7 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 606 - 904 0 None A608T Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QO7A 1.605 Inactive DFGin‑BLAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 595 - 904 0 PTR701 None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QO9A 1.55 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_noiai APEdist_aaai ANP ATPlike 608 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOQA 1.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 595 - 906 0 PTR701 None Ephrin type-A receptor 3
TYR EPHB1 EPHB1_HUMAN 7KPMA 1.608 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 611 - 888 0 PTR647 None Ephrin type-B receptor 1
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR FGFR1 FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 2PWLA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,N549H Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PWLB 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,N549H Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGLA 1.861 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 468 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGLB 1.861 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J96B 2.297 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 766 0 None C491A,K659M Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J98B 2.307 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 461 - 764 0 None C491A,K659Q Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVFA 1.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR586,PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3CLYA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 468 - 772 0 PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99A 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99B 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99C 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99D 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 465 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYA 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYB 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYC 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYD 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95A 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95B 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95C 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95D 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZ5A 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZ5B 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97A 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97B 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97C 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97D 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZPA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZPB 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZRA 3.0 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,K641R Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZRB 3.0 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 None C491A,K641R Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UHNA 2.909 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UHNB 2.909 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGXA 2.349 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGXB 2.349 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UI0B 2.05 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2Q0BA 2.9 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2Q0BB 2.9 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PY3A 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PY3B 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5EG3A 2.606 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 466 - 774 0 PTR769 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QA 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR3 FGFR3_HUMAN 4K33A 2.341 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 459 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXA 2.199 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 456 - 757 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXB 2.199 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 455 - 756 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR HCK HCK_HUMAN 1AD5A 2.6 Inactive DFGin‑BLAminus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 1AD5B 2.6 Inactive DFGin‑BLAminus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR IGF1R IGF1R_HUMAN 1K3AA 2.1 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 988 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHA 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHB 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHC 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR INSR INSR_HUMAN 1IR3A 1.9 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 1008 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S,Y1011F Insulin receptor
TYR INSR INSR_HUMAN 3BU5A 2.1 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ATP ATPlike 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 4XLVA 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 1001 - 1310 0 PTR999,PTR1185,PTR1189,PTR1190 Y992F,C1008S Insulin receptor
TYR INSR INSR_HUMAN 1I44A 2.4 Inactive DFGin‑None in-out none-out TYR APEdihe_nnoai APEdist_aaai ACP ATPlike 1013 - 1310 0 None C1008S,Y1011F,D1188A Insulin receptor
TYR JAK1-2 JAK1_HUMAN 5KHWA 2.47 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6C7YA 2.499 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 869 - 1153 0 PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHWB 2.47 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK2-1 JAK2_HUMAN 5I4NA 1.54 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 809 0 None E596A,V617F,W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVRA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None V617F,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVQA 1.75 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08A 2.2 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08B 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR KIT KIT_HUMAN 1PKGA 2.9 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 567 - 927 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 1PKGB 2.9 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 566 - 929 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit
TYR LCK LCK_HUMAN 1QPCA 1.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR MERTK MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 3DKCA 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ATP ATPlike 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MST1R RON_HUMAN 3PLSA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 1060 - 1357 0 None M1254T Macrophage-stimulating protein receptor
TYR MST1R RON_HUMAN 8ZKDA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao ANP ATPlike 1060 - 1357 0 None None Macrophage-stimulating protein receptor
TYR PTK2 FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 2IJMA 2.187 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 414 - 688 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 1MP8A 1.6 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2B FAK2_HUMAN 3FZPA 2.1 Inactive DFGout‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 419 - 692 0 None None Protein-tyrosine kinase 2-beta
TYR RET RET_HUMAN 2IVTA 2.6 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai AMP ATPlike 703 - 1012 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NE7A 1.99 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai AMP ATPlike 705 - 1013 0 PTR900,PTR905 G810A Proto-oncogene tyrosine-protein kinase receptor Ret
TYR SRC SRC_HUMAN 2SRCA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 87 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SYK KSYK_HUMAN 4FL1A 1.79 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FL3A 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 9 - 635 0 None Y348F,Y352F Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FL2A 2.19 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 9 - 635 0 None None Tyrosine-protein kinase SYK
TYR TNK2 ACK1_HUMAN 1U54A 2.8 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ACP ATPlike 115 - 390 0 PTR284 None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 1U54B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 117 - 388 0 None None Activated CDC42 kinase 1
TYR TYK2-2 TYK2_HUMAN 4GVJA 2.03 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 889 - 1176 0 None C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C03A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C03B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR ZAP70 ZAP70_HUMAN 2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70
TYR ZAP70 ZAP70_HUMAN 4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70

All / All / ATPlike

Total number of chains: 1026
Active chains: 310
Total number of genes: 200
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 637 62.1% 8QCGA
DFGin BLBplus 112 10.9% 2SRCA
DFGin None 80 7.8% 5I4NA
DFGin ABAminus 53 5.2% 7N8TA
DFGin BLBtrans 40 3.9% 5W7TA
DFGin BLBminus 33 3.2% 4LGDA
DFGinter None 30 2.9% 9D5IA
None None 27 2.6% 4JQEA
DFGin BLAplus 7 0.7% 6PNXB
DFGout None 7 0.7% 4I94A
All chains
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Representatives
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All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 6XX7A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 77 - 406 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC MPK4 MPK4_ARATH 7W5CA 2.201 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo ANP ATPlike 18 - 372 0 None None Mitogen-activated protein kinase 4 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3UIMA 2.2 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii ANP ATPlike 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6A 1.898 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6B 1.898 Inactive DFGin‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXA 2.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYA 2.28 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYB 2.28 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVA 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVB 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWA 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWB 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMB 2.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC GRK1 GRK1_BOVIN 3T8OA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 532 0 None L166K Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 5 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4ZA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51A 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51B 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9D 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW5G 3.8 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW8G 3.5 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 329 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW9G 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1Q24A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 TPO198,SEP339 V124A,L174M cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW7G 6.0 Inactive None‑None out-none in-out nonTYR APEdihe_aaini APEdist_iiio ANP ATPlike 13 - 351 0 None None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
TYR LET23 LET23_CAEEL 5WNOA 2.386 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nooai APEdist_aaao ANP ATPlike 876 - 1190 0 None None Receptor tyrosine-protein kinase let-23 Caenorhabditis elegans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 4 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CK1 HRR25 Q6FS46_CANGA 4XH0A 1.99 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 397 0 None K38R non-specific serine/threonine protein kinase Candida glabrata
CK1 HRR25 Q6FS46_CANGA 4XHGA 2.15 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iioo ADP ATPlike 2 - 397 0 None K38R non-specific serine/threonine protein kinase Candida glabrata
CMGC CDK7 G0SFC6_CHATD 6Z4XB 2.98 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 78 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
CMGC CDK7 G0SFC6_CHATD 6Z4XE 2.98 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 77 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
AGC PRKACA KAPCA_CRIGR 6EH2A 1.76 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EM6A 1.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EM7A 1.238 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EMAA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ESAA 1.307 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y8CA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CMGC CK2 Q5KF69_CRYD1 6ISEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CK2 Q5KF69_CRYD1 6ISEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CKA1 J9VNH4_CRYN9 6KO6B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 334 0 None None Casein kinase II subunit alpha Cryptococcus neoformans
CAMK CDPK1 A3FQ16_CRYPI 3IGOA 2.25 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 4Y5QA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo AMP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9D8SA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AMP ATPlike 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK3 Q5CS01_CRYPI 3LIJA 1.9 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 42 - 516 0 None None Calcium-dependent protein kinase 1 Cryptosporidium parvum
CAMK CDPK4-2 Q5CZ29_CRYPI 3HKOA 1.8 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoi ANP ATPlike 126 - 452 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CMGC CDK Q5CRJ8_CRYPI 3NIZA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 1 - 293 0 None None Cyclin-dependent kinase 2 homolog Cryptosporidium parvum
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
CAMK PLK1 Q4KMI8_DANRE 3D5WA 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 310 0 TPO196 None Serine/threonine-protein kinase PLK Danio rerio
TKL ROCO4 ROCO4_DICDI 4F0FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1OA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
CAMK CAMKII KCC2A_DROME 5FG8A 1.955 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5H9BA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5HU3A 1.885 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 272 0 None D136N Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK OBSCN-1 OBSCN_DROME 8AK3A 1.9 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 3186 - 3477 0 None None Protein Obscurin Drosophila melanogaster
CMGC BSK JNK_DROME 5AWMA 1.79 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 7 - 362 0 None None Stress-activated protein kinase JNK Drosophila melanogaster
OTHER BUBR1 A1Z6I7_DROME 6JKMA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo ADP ATPlike 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
CAMK CDPK Q3HNM4_EIMTE 4YSJA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
CAMK CDPK Q3HNM4_EIMTE 4YSJB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
TYR PTK2 FAK1_CHICK 2J0LA 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao ANP ATPlike 411 - 686 0 PTR576,PTR577 None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 3DQWA 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWB 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWC 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 258 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWD 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 257 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXA 2.3 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXB 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC CDK A8BZ95_GIAIC 3GC0A 2.0 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoni APEdist_nooo AMP ATPlike 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
AGC AKT1 AKT1_HUMAN 4EKKA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 4EKKB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 1O6KA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 479 0 TPO309 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 1O6LA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 477 0 TPO309 None RAC-beta serine/threonine-protein kinase Homo sapiens
AGC CDC42BPB MRCKB_HUMAN 4UAKA 1.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta Homo sapiens
AGC GRK4 GRK4_HUMAN 4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
AGC GRK4 GRK4_HUMAN 4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
AGC GRK5 GRK5_HUMAN 4TNDA 1.802 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 543 0 None None G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9CKRA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9CKSA 3.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK6 GRK6_HUMAN 2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 1H1WA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 71 - 359 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 2BIYA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 72 - 359 0 None S241A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3HRCA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 4RRVA 1.412 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5ACKA 1.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 73 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPC 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPD 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 4CT2A 1.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5MRDA 1.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PKN2 PKN2_HUMAN 4CRSA 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 646 - 984 0 SEP755,TPO816,TPO958 None Serine/threonine-protein kinase N2 Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB8A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB5A 1.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6NO7E 3.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6NO7G 3.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB7A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB7B 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6BYRA 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6BYRC 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9EDCA 4.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9EDDA 6.3 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9EDEA 5.9 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP11,SEP140,TPO198 L206R cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB6B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 9 - 351 0 SEP11,TPO198,SEP339 L206R cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE1A 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE1B 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE2B 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCI KPCI_HUMAN 8R3YI 3.68 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 585 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 3A8WA 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 3A8WB 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LIHA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 248 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LIHB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LI9A 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 248 - 589 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LI1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 589 0 TPO412,SEP484,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 9EJMB 3.33 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2A 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 336 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2B 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 346 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2C 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2D 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 344 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7LV3A 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 57 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7LV3B 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 58 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC RPS6KA1-1 KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOA 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 45 - 348 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOE 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOI 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_onnn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOK 2.75 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aanoi APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOC 2.75 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 46 - 347 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 7OPOG 2.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aanni APEdist_oonn ANP ATPlike 46 - 348 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA6-1 KS6A6_HUMAN 6G76B 3.0 Inactive DFGinter‑None none-none out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 51 - 349 0 SEP232 None Ribosomal protein S6 kinase alpha-6 Homo sapiens
AGC RPS6KA6-1 KS6A6_HUMAN 6G78A 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaoii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6 Homo sapiens
AGC RPS6KA6-1 KS6A6_HUMAN 6G78B 2.5 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ANP ATPlike 51 - 349 0 None S232E Ribosomal protein S6 kinase alpha-6 Homo sapiens
AGC SGK1 SGK1_HUMAN 2R5TA 1.9 Inactive DFGinter‑None none-none out-out nonTYR APEdihe_aaiio APEdist_oooo ANP ATPlike 82 - 378 0 None S74A,S78A,S397A,S401A Serine/threonine-protein kinase Sgk1 Homo sapiens
AGC STK38 STK38_HUMAN 6BXIA 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 82 - 414 0 None None Serine/threonine-protein kinase 38 Homo sapiens
AGC STK38 STK38_HUMAN 6BXIB 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 83 - 414 0 None None Serine/threonine-protein kinase 38 Homo sapiens
CAMK AURKA AURKA_HUMAN 4C3PD 2.69 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nooo ACP ATPlike 125 - 390 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWA 2.7 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWB 2.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 507 - 390 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWC 2.7 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4BN1A 2.499 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 126 - 388 0 TPO287,TPO288 V174M Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 1MQ4A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 126 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DNRA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 126 - 390 0 TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DT3A 2.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ATP ATPlike 127 - 390 0 TPO287 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 1OL5A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 123 - 388 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 1OL7A 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 127 - 390 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5G15A 2.06 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 126 - 390 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 2DWBA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 126 - 389 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6CPFA 2.3 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 128 - 392 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6VPGA 2.64 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DRDA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ATP ATPlike 127 - 390 0 None T287A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4DEEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 124 - 394 0 None T287D Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6VPIA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 104 - 389 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5LXMA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4CEGA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 127 - 391 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5G1XA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 1OL6A 3.0 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 128 - 388 0 None D274N Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4C3PA 2.69 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaooi APEdist_oooo ACP ATPlike 125 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 2C6DA 2.2 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ANP ATPlike 126 - 390 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5ODTA 2.021 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 392 0 None D274N,C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4C3RA 2.79 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 127 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6C83B 2.55 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ACP ATPlike 127 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5L8JA 1.68 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 126 - 391 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5L8KA 1.79 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5L8LA 1.67 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iooo ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8PR7A 2.76 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 124 - 389 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6VPJA 2.1 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 104 - 389 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6VPHA 2.14 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oioo ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6C83A 2.55 Inactive None‑None out-none none-out nonTYR APEdihe_aaooi APEdist_nnno ACP ATPlike 127 - 389 0 None None Aurora kinase A Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG7A 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ATP ATPlike 9 - 277 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG9A 2.4 Inactive DFGinter‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 10 - 314 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG9B 2.4 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaini APEdist_nnno ATP ATPlike 14 - 314 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG8A 2.2 Inactive None‑None out-none none-out nonTYR APEdihe_aanno APEdist_nnnn ATP ATPlike 10 - 299 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG8B 2.2 Inactive None‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnno ATP ATPlike 14 - 299 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJSA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UIRA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UIRB 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJPA 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJTA 2.1 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CASK CSKP_HUMAN 3MFRA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3MFSA 2.1 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3MFUA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 9M6GA 1.7 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 312 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 9M5YA 1.8 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 312 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0HA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0HB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CHEK1 CHK1_HUMAN 7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 5OOPA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK2 CHK2_HUMAN 2CN5A 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 209 - 504 0 None None Serine/threonine-protein kinase Chk2 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 2W4JA 1.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTB 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTC 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 5 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTD 2.65 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 1IG1A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 294 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 1JKKA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 293 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 1JKLA 1.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 294 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3EH9A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3EHAA 1.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3F5GA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3F5UA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 2W4KA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3DFCB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23K Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3GU4A 1.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3GU5A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3GU6A 1.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3GU7A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 2 - 277 0 None Q23V Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 2XUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None E182A Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTA 2.65 Inactive DFGin‑BLBminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DCLK1 DCLK1_HUMAN 5JZJA 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 374 - 648 0 None None Serine/threonine-protein kinase DCLK1 Homo sapiens
CAMK DCLK1 DCLK1_HUMAN 5JZJB 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 382 - 648 0 None None Serine/threonine-protein kinase DCLK1 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 1NY3A 3.0 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MELK MELK_HUMAN 4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSE 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSF 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PHKG1 PHKG1_HUMAN 8Z5RC 3.52 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Homo sapiens
CAMK PHKG1 PHKG1_HUMAN 8Z5TC 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Homo sapiens
CAMK PHKG1 PHKG1_HUMAN 8Z5TG 3.74 Inactive DFGin‑BLAminus out-none out-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Homo sapiens
CAMK PHKG1 PHKG1_HUMAN 8Z5TK 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Homo sapiens
CAMK PHKG1 PHKG1_HUMAN 8Z5TO 3.74 Inactive DFGin‑BLAminus out-none out-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 383 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXTA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 306 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUA 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUB 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUC 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 34 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUD 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1XR1A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 308 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 3A99A 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 2BZKB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 8X72A 2.2 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiio APEdist_ioio ANP ATPlike 37 - 330 0 None None Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 2OU7A 2.4 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiio APEdist_ioio ANP ATPlike 37 - 328 0 None T210V Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK4 PLK4_HUMAN 3COKA 2.25 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 266 0 None None Serine/threonine-protein kinase PLK4 Homo sapiens
CAMK PLK4 PLK4_HUMAN 3COKB 2.25 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 266 0 None None Serine/threonine-protein kinase PLK4 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5B 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK STK11 STK11_HUMAN 2WTKC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 47 - 342 0 None D194A Serine/threonine-protein kinase STK11 Homo sapiens
CAMK STK11 STK11_HUMAN 2WTKF 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 45 - 340 0 None D194A Serine/threonine-protein kinase STK11 Homo sapiens
CAMK STK17B ST17B_HUMAN 6QF4A 2.495 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nioo ADP ATPlike 18 - 308 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CAMK STK17B ST17B_HUMAN 7Q7CA 2.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CAMK STK17B ST17B_HUMAN 7Q7DA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CAMK STK17B ST17B_HUMAN 7Q7EA 2.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo ATP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU6A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU6B 2.05 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7FA 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7FB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7GA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo AMP ATPlike 8 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7GB 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi AMP ATPlike 7 - 293 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7HA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7HB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6AC9A 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 342 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6AC9B 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6AC9C 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6AC9D 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 9SKQA 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiii ANP ATPlike 3 - 288 0 TPO161 None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK11B CD11B_HUMAN 9I9IK 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 440 - 740 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK12 CDK12_HUMAN 4CXAA 3.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 718 - 1050 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 4NSTA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 716 - 1046 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 4NSTC 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 717 - 1045 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK13 CDK13_HUMAN 5EFQA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 695 - 1025 0 TPO871 None Cyclin-dependent kinase 13 Homo sapiens
CMGC CDK13 CDK13_HUMAN 5EFQC 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 697 - 1031 0 TPO871 None Cyclin-dependent kinase 13 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOOA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 Q131E Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOOC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 Q131E Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOMA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 H84S,Q85M,Q131E Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOMC 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 H84S,Q85M,Q131E Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4I3ZA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4I3ZC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHRA 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHRC 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHWA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHWC 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1FINA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1FINC 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1FQ1B 3.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_oioo ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1JSTA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1JSTC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CJMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 292 0 PTR15,TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CJMC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 297 0 PTR15,TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4II5A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4II5C 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GY3A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GY3C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1QMZA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1QMZC 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCHC 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCIA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCIC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9I9JK 3.1 Inactive DFGin‑BLAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 6 - 284 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9I9KK 2.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 2 - 292 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9QCVK 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 1 - 292 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOQA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 297 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOQC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOJA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 H84S,Q85M,K89D Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EOJC 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 H84S,Q85M,K89D Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1HCKA 1.9 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8FP5A 1.7 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1B38A 2.0 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1B39A 2.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK7 CDK7_HUMAN 6XBZJ 2.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 312 0 SEP164 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R99A 1.81 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 10 - 311 0 None W132R,S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8P6YJ 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9I9IJ 3.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 12 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9I9JJ 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ADP ATPlike 11 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9I9KJ 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ADP ATPlike 10 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9QCVJ 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 10 - 346 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9SKQJ 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 9 - 346 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9HIYJ 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None D97N Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 1UA2A 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 1UA2B 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 1UA2C 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 1UA2D 3.02 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ATP ATPlike 13 - 311 0 TPO170 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R9BA 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 1 - 311 0 None S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R9BB 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 3 - 310 0 None S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R9BC 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo ANP ATPlike 8 - 311 0 None S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R9BD 2.21 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ANP ATPlike 9 - 311 0 None S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK9 CDK9_HUMAN 3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3JUHA 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3JUHB 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6Z19B 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3NSZA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 4NH1A 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ACP ATPlike 3 - 332 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 4NH1B 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ACP ATPlike 2 - 333 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 1PJKA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 332 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 2PVRA 1.605 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3WOWA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 335 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 1JWHA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 337 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3U87A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3U87B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OQUB 2.324 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5ORKB 2.143 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 326 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 7QUXA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 SEP2 None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6YZHA 1.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5CU6A 1.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A2 CSK22_HUMAN 8QCGA 1.04 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 330 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CMGC CSNK2A2 CSK22_HUMAN 8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 7A4OB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM0A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 8XN6B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 26 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC MAPK1 MK01_HUMAN 4H3QA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo ANP ATPlike 9 - 360 0 None R77A,C161S,I255G,E314A Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4IZ5A 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4IZ5B 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4IZ5C 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4IZ5D 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 2Y9QA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FMQA 2.098 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4NIFB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4NIFE 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 8PSRA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 1 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 3TEIA 2.404 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 358 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4H3PA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4H3PD 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK12 MK12_HUMAN 1CM8A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK12 MK12_HUMAN 1CM8B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK7 MK07_HUMAN 4IC7A 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 46 - 400 0 None None Mitogen-activated protein kinase 7 Homo sapiens
CMGC MAPK7 MK07_HUMAN 4IC7D 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooi ANP ATPlike 47 - 399 0 None None Mitogen-activated protein kinase 7 Homo sapiens
CMGC MAPK8 MK08_HUMAN 6ZR5A 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 3 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 6ZR5B 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 4 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 2XRWA 1.33 Inactive DFGin‑ABAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 2XS0A 2.6 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ANP ATPlike 6 - 365 0 None T183V,Y185F Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 9FT9A 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 7 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9B 2.34 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK9 MK09_HUMAN 7N8TA 1.69 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iioo AMP ATPlike 10 - 364 0 None None Mitogen-activated protein kinase 9 Homo sapiens
CMGC PRP4K PRP4K_HUMAN 4IFCA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
CMGC PRP4K PRP4K_HUMAN 4IFCB 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
CMGC PRP4K PRP4K_HUMAN 4IIRA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
CMGC PRP4K PRP4K_HUMAN 4IIRB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
CMGC SRPK1 SRPK1_HUMAN 3BEGA 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 69 - 655 0 None None SRSF protein kinase 1 Homo sapiens
CMGC SRPK1 SRPK1_HUMAN 1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
NEK NEK2 NEK2_HUMAN 2W5BA 2.4 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo AGS ATPlike 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2W5AA 1.55 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ADP ATPlike 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK7 NEK7_HUMAN 9NFQC 3.25 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 2WQNA 2.3 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 21 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
OTHER BUB1 BUB1_HUMAN 4QPMA 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 4QPMB 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1081 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 4R8QA 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iooo ADP ATPlike 736 - 1083 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 5DMZA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 5DMZB 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 256 - 544 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn ADP ATPlike 255 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 257 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER TLK2 TLK2_HUMAN 5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCPB 4.1 Pseudo DFGin‑BLBtrans out-none out-out nonTYR APEdihe_aaoao APEdist_oooo ATP ATPlike 503 - 841 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCSA 4.4 Pseudo DFGin‑None out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 503 - 1055 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCSB 4.4 Pseudo None‑None out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 505 - 1055 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQDA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQIA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5YT3C 2.9 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6U2GA 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6V2WB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5YT3B 2.9 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5YT3D 2.9 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 39 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5YT3A 2.9 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ANP ATPlike 39 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7F2XA 2.007 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ANP ATPlike 45 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3W8QA 2.2 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo AGS ATPlike 39 - 382 0 None T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALNA 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 83 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALNB 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 84 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALOA 2.6 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoao APEdist_oooo ANP ATPlike 95 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALNC 2.3 Inactive None‑None na-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 100 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4DN5A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_noii AGS ATPlike 332 - 675 0 None S549D Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4DN5B 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_noii AGS ATPlike 333 - 675 0 None S549D Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 8YHWA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 8YHWB 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 8YHWC 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii AGS ATPlike 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6CQDA 2.12 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 2 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6CQDB 2.12 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 4 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U40A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE OXSR1 OXSR1_HUMAN 3DAKA 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 6 - 295 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 3DAKB 2.25 Inactive DFGin‑BLBtrans out-out out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 6 - 295 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 3DAKC 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 7 - 295 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 3DAKD 2.25 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ANP ATPlike 7 - 295 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 2VWIB 2.15 Inactive DFGin‑BLBtrans out-out out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 9 - 292 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 2VWIC 2.15 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo ANP ATPlike 9 - 292 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 2VWID 2.15 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 6 - 298 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE OXSR1 OXSR1_HUMAN 2VWIA 2.15 Inactive DFGin‑None none-none out-out nonTYR APEdihe_aaioi APEdist_nnno ANP ATPlike 13 - 292 0 None None Serine/threonine-protein kinase OSR1 Homo sapiens
STE PAK1 PAK1_HUMAN 3Q53A 2.09 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 250 - 541 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 3Q4ZA 1.887 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 251 - 545 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK3 PAK3_HUMAN 6FD3A 1.52 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 261 - 556 0 None A537D Serine/threonine-protein kinase PAK 3 Homo sapiens
STE PAK4 PAK4_HUMAN 4XBRA 2.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 177 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIFA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 296 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIFB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 297 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIGA 3.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 298 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4JDIA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 5UPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 588 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIEA 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 49 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIEB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 49 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7S46A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7S47A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIGB 3.01 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 298 - 590 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE STK24 STK24_HUMAN 3A7HA 1.96 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 310 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 3A7HB 1.96 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 17 - 310 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 3A7JA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 311 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 4QMLA 1.882 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 310 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 4O27B 3.185 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 30 - 309 0 None T190E Serine/threonine-protein kinase 24 Homo sapiens
STE STK3 STK3_HUMAN 6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STRADA STRAA_HUMAN 2WTKB 2.65 Pseudo DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 61 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 2WTKE 2.65 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 3GNIB 2.35 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ATP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 8VSUB 2.86 Pseudo DFGin‑None out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ADP ATPlike 60 - 401 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE TAOK3 TAOK3_HUMAN 6BDNA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 8 - 314 0 None R2A,K3A Serine/threonine-protein kinase TAO3 Homo sapiens
STE TNIK TNIK_HUMAN 7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNQA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 206 - 496 0 None K493A Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNRA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 208 - 496 0 None None Activin receptor type-1 Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BRAF BRAF_HUMAN 9AXXB 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYPC 3.29 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 363 - 733 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDB 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGFB 2.61 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 164 - 460 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHTA 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHTB 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHWA 3.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 540 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LI4A 3.1 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO2E 4.13 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO8C 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO8E 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9F 3.48 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH5A 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH5C 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LI3A 3.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9E 3.48 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH4A 4.1 Inactive None‑None out-none out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21 Homo sapiens
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G2IA 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 229 - 502 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G2IB 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 232 - 500 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G2FB 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 234 - 502 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
TYR ALK ALK_HUMAN 3LCTA 2.1 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3VJNA 2.34 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8DSWA 2.39 Inactive DFGin‑BLAminus none-none in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3VJOA 2.64 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1019 0 None G719S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1019 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 698 - 1015 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1014 0 None I706Q Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1DA 2.4 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 700 - 1021 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKB 2.4 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1020 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WXNB 1.76 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV4A 2.2 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4A 2.99 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 698 - 1022 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXMA 2.192 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO4B 1.621 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2GS7A 2.6 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 703 - 1012 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2GS7B 2.6 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1016 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3GT8A 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3GT8B 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 701 - 1007 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3GT8C 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 699 - 1007 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3GT8D 2.955 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 701 - 1010 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNOA 1.55 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 700 - 1015 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNNB 1.9 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 700 - 1014 0 None I706Q Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIWB 3.1 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIWD 3.1 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIXB 3.1 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIXD 3.1 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIYB 2.981 Inactive DFGin‑None in-in in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RIYD 2.981 Inactive DFGin‑None in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9VA 1.458 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AGS ATPlike 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 1MQBA 2.3 Inactive DFGin‑BLAminus in-out none-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 605 - 887 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 1MQBB 2.3 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 602 - 883 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJAB 1.75 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9WA 1.359 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 605 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJCA 2.3 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai ACP ATPlike 590 - 976 0 None S901E Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJCB 2.3 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None S901E Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJAA 1.75 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 976 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QOCA 1.25 Inactive DFGin‑BLAminus in-out in-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 613 - 906 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 3FXXA 1.7 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 606 - 904 0 None A608T Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QO7A 1.605 Inactive DFGin‑BLAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 595 - 904 0 PTR701 None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QO9A 1.55 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_noiai APEdist_aaai ANP ATPlike 608 - 904 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QOQA 1.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 595 - 906 0 PTR701 None Ephrin type-A receptor 3 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 7KPMA 1.608 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 611 - 888 0 PTR647 None Ephrin type-B receptor 1 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PWLA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,N549H Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PWLB 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,N549H Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UGLA 1.861 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 468 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UGLB 1.861 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 467 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J96B 2.297 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 766 0 None C491A,K659M Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J98B 2.307 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 461 - 764 0 None C491A,K659Q Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVFA 1.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR586,PTR656,PTR657 C491A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 3CLYA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 468 - 772 0 PTR656,PTR657 C491A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J99A 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J99B 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J99C 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J99D 1.847 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 465 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVYA 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVYB 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVYC 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVYD 2.2 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J95A 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J95B 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J95C 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J95D 2.377 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZ5A 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZ5B 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J97A 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J97B 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J97C 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 4J97D 2.548 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZPA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZPB 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZRA 3.0 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,K641R Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PZRB 3.0 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 None C491A,K641R Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UHNA 2.909 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UHNB 2.909 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UGXA 2.349 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UGXB 2.349 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5UI0B 2.05 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 462 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2Q0BA 2.9 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2Q0BB 2.9 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PY3A 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PY3B 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5EG3A 2.606 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 466 - 774 0 PTR769 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6V6QA 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 466 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6V6QB 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6V6QD 2.46 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 4K33A 2.341 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 459 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 6PNXA 2.199 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 456 - 757 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 6PNXB 2.199 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 455 - 756 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3 Homo sapiens
TYR HCK HCK_HUMAN 1AD5A 2.6 Inactive DFGin‑BLAminus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 1AD5B 2.6 Inactive DFGin‑BLAminus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK Homo sapiens
TYR IGF1R IGF1R_HUMAN 1K3AA 2.1 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 988 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 1JQHA 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 1JQHB 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 1JQHC 2.1 Inactive DFGin‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor Homo sapiens
TYR INSR INSR_HUMAN 1IR3A 1.9 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 1008 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S,Y1011F Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 3BU5A 2.1 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ATP ATPlike 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 4XLVA 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 1001 - 1310 0 PTR999,PTR1185,PTR1189,PTR1190 Y992F,C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 1I44A 2.4 Inactive DFGin‑None in-out none-out TYR APEdihe_nnoai APEdist_aaai ACP ATPlike 1013 - 1310 0 None C1008S,Y1011F,D1188A Insulin receptor Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5KHWA 2.47 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6C7YA 2.499 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 869 - 1153 0 PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5KHWB 2.47 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5I4NA 1.54 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 809 0 None E596A,V617F,W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 4FVRA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None V617F,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 4FVQA 1.75 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C08A 2.2 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C08B 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR KIT KIT_HUMAN 1PKGA 2.9 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 567 - 927 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 1PKGB 2.9 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 566 - 929 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR LCK LCK_HUMAN 1QPCA 1.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck Homo sapiens
TYR MERTK MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 3DKCA 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ATP ATPlike 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MST1R RON_HUMAN 3PLSA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 1060 - 1357 0 None M1254T Macrophage-stimulating protein receptor Homo sapiens
TYR MST1R RON_HUMAN 8ZKDA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao ANP ATPlike 1060 - 1357 0 None None Macrophage-stimulating protein receptor Homo sapiens
TYR PTK2 FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 2IJMA 2.187 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 414 - 688 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 1MP8A 1.6 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2B FAK2_HUMAN 3FZPA 2.1 Inactive DFGout‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 419 - 692 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
TYR RET RET_HUMAN 2IVTA 2.6 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai AMP ATPlike 703 - 1012 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 6NE7A 1.99 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai AMP ATPlike 705 - 1013 0 PTR900,PTR905 G810A Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR SRC SRC_HUMAN 2SRCA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 87 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SYK KSYK_HUMAN 4FL1A 1.79 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4FL3A 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 9 - 635 0 None Y348F,Y352F Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4FL2A 2.19 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 9 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR TNK2 ACK1_HUMAN 1U54A 2.8 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ACP ATPlike 115 - 390 0 PTR284 None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 1U54B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 117 - 388 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 4GVJA 2.03 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ADP ATPlike 889 - 1176 0 None C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C03A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C03B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR ZAP70 ZAP70_HUMAN 2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70 Homo sapiens
TYR ZAP70 ZAP70_HUMAN 4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70 Homo sapiens
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
CMGC MAPK A0A3Q8ITZ9_LEIDO 4QNYA 2.257 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooo ANP ATPlike 4 - 350 0 None None Mitogen activated protein kinase, putative Leishmania donovani
CMGC MAPK A0A3Q8ITZ9_LEIDO 4QNYB 2.257 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooo ANP ATPlike 4 - 350 0 None None Mitogen activated protein kinase, putative Leishmania donovani
TKL LYK3 LYK3_MEDTR 9GFZA 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 302 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
AGC PRKACA KAPCA_MOUSE 6MM6C 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM6E 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7A 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7D 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM8C 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKND 2.75 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKOE 2.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKPE 2.85 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 17 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTB 3.5 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4O21A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E11A 3.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM5E 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3PVBA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1ATPE 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1BKXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1L3RE 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 2QCSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FJQE 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDBA 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG0E 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH5A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DINA 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 10 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPTE 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPUE 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7A 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7C 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7UJXE 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7V0GE 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 17 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DFXE 1.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6RA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2UA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2VA 1.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2WA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IACA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IADA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAFA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAIA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAKA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAYA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB0A 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB1A 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW4A 1.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW5A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW6A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6E21A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E0ZA 2.162 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E12A 2.796 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1JBPE 2.2 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 10 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG3E 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198 R337A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3O7LB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 18 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FHIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 C200A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QAME 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 E209A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QALE 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 R281A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTA 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC RPS6KA3-1 KS6A3_MOUSE 3G51A 1.8 Inactive DFGin‑None none-none out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 47 - 346 0 None None Ribosomal protein S6 kinase alpha-3 Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B56B 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B57B 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABB 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK MELK MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZE 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZF 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZG 2.6 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZH 2.6 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
STE STK39 STK39_MOUSE 5D9HA 3.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo ATP ATPlike 65 - 363 0 None None STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5D9HB 3.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ATP ATPlike 65 - 364 0 None None STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5DBXA 2.5 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooo ANP ATPlike 65 - 365 0 None T243D STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5DBXB 2.5 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooo ANP ATPlike 65 - 364 0 None T243D STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNIA 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 9 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 1JPAA 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 892 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 1JPAB 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 891 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
TYR LYN LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
TYR SRC SRC_MOUSE 8XN8A 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 534 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
TYR SRC SRC_MOUSE 6F3FA 2.418 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 531 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PA 2.37 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_iooo ACP ATPlike 1 - 278 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PB 2.37 Inactive None‑None in-out none-out nonTYR APEdihe_aanno APEdist_onnn ACP ATPlike 2 - 277 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y0XA 1.74 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii ADP ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y12A 1.9 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii AGS ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
CAMK PHKG1 PHKG1_RABIT 2PHKA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 291 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1QL6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 292 0 None E183S Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1PHKA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 292 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUQC 3.22 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP ATPlike 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUWC 2.88 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 2Y4IC 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP ATPlike 37 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
OTHER FLS2 FLS2_ORYSJ 8JUPA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 861 - 1176 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER FLS2 FLS2_ORYSJ 8JUVA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 861 - 1178 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
CAMK CDPK1 CDPK1_PLABA 3Q5IA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 38 - 518 0 None None Calcium-dependent protein kinase 1 Plasmodium berghei
CMGC CK1 Q8IIR9_PLAF7 5XVUA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC CK1 Q8IIR9_PLAF7 5XVUB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC CK1 Q8IIR9_PLAF7 5XVUC 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC MAPK Q7KQK7_PLAF7 3NIEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 95 - 499 0 None None Mitogen-activated protein kinase Plasmodium falciparum
CMGC MAPK Q7KQK7_PLAF7 3NIEB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 95 - 505 0 None None Mitogen-activated protein kinase Plasmodium falciparum
CMGC PSTK1 Q8IL19_PLAF7 3LLTA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 535 - 875 0 None None Protein serine/threonine kinase-1 Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYB 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYG 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 157 - 559 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYH 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER PK7 O96214_PLAFA 2PMLX 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 316 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
AGC PKG KGP_PLAVS 5DZCA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 843 0 None None cGMP-dependent protein kinase Plasmodium vivax
CMGC MPS1 MPS1_PYROR 8ZTCA 2.26 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi AMP ATPlike 5 - 408 0 None None Mitogen-activated protein kinase MPS1 Pyricularia oryzae
AGC PRKACA KAPCA_RAT 3TNQB 3.097 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 18 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus
AGC PRKCB KPCB_RAT 3PFQA 4.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 101 - 668 0 TPO500,TPO642,SEP661 C71S,C217S,R622S Protein kinase C beta type Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S33A 1.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 355 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S32A 1.34 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4GT3A 1.68 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4GVAA 1.83 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 7UGBA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S34A 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 1GOLA 2.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 2 - 358 0 None K52R Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQVA 2.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_oiii ANP ATPlike 4 - 354 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQXA 1.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 353 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQWA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 354 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TA 2.01 Inactive DFGin‑BLBtrans na-na out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TB 2.01 Inactive DFGin‑BLBtrans na-na out-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
AGC CBK1 CBK1_YEAST 4LQSA 3.3 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 294 - 749 0 None D475A Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 5NCLA 3.15 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 266 - 756 0 None D475A Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 4LQPA 4.5 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 282 - 749 0 None D475A,T743E Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 4LQQA 3.6 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 282 - 749 0 None D475A,T743E Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 4PDSA 2.9 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 191 - 490 0 None A225S,D339A Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 4PDSB 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 191 - 494 0 None A225S,D339A Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZVB 3.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo ANP ATPlike 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZVA 3.1 Inactive DFGin‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 16 - 465 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4FI1A 2.09 Inactive None‑None out-na in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4JQEA 1.77 Inactive None‑None out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4MWHA 2.09 Inactive None‑None out-na in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9HA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9IA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9JA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2F9GA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 1 - 353 0 PTR182 None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC KIN28 KIN28_YEAST 6XI8A 3.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 6 - 303 0 TPO162 None Serine/threonine-protein kinase KIN28 Saccharomyces cerevisiae
CMGC KIN28 KIN28_YEAST 7KUEA 3.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 6 - 303 0 TPO162 None Serine/threonine-protein kinase KIN28 Saccharomyces cerevisiae
CMGC PHO85 PHO85_YEAST 2PMIA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo AGS ATPlike 19 - 302 0 None None Cyclin-dependent protein kinase PHO85 Saccharomyces cerevisiae
CMGC PHO85 PHO85_YEAST 4KRCA 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 2 - 302 0 None None Cyclin-dependent protein kinase PHO85 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q8YA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q97A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 143 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99B 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 142 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
TKL NCGRLOCUS634 A0ACD6BAX3_9POAL 8HO6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 305 0 TPO184,SEP187,TPO188 None ScRIPK kinase protein Saccharum hybrid cultivar
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSA 3.07 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSB 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 946 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
CK1 CKI1 CKI1_SCHPO 1CSNA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
OTHER None A0ACD6BAW3_SERSF 5HNVA 1.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1QA 1.602 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1SA 1.45 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ACP ATPlike 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1TA 1.55 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ADP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
AGC PRKACA KAPCA_PIG 1CDKA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
AGC PRKACA KAPCA_PIG 1CDKB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
CAMK CDPK1 Q9BJF5_TOXGO 4IEBA 2.05 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 507 0 None G128M non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK1 Q9BJF5_TOXGO 3HX4A 1.95 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 503 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK1 Q9BJF5_TOXGO 3KU2A 2.3 Inactive None‑None out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 44 - 507 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP9A 2.8 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AN2 ATPlike 121 - 568 0 SEP205,TPO530 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
CMGC TVAG125560 A2F9N1_TRIV3 9AV7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 318 0 None None non-specific serine/threonine protein kinase Trichomonas vaginalis
CAMK AURKBA AUKBA_XENLA 4C2WA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2WB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
OTHER YOPO Q93KQ6_YEREN 5CE3B 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 5CE3D 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
CMGC ACK2 CSK2A_MAIZE 1DAWA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5A 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5B 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5C 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5D 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1LP4A 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays

All / All / ATPlike

Total number of chains: 340
Active chains: 132
Total number of genes: 83
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 219 64.4% 6EM7A
DFGin None 33 9.7% 4CYIA
DFGin ABAminus 25 7.4% 4C2WA
DFGin BLBminus 20 5.9% 5M06B
DFGin BLBplus 20 5.9% 8XN8A
None None 16 4.7% 4JQEA
DFGin BLBtrans 5 1.5% 5W7TA
DFGout None 2 0.6% 4I94A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 6XX7A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 77 - 406 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
CMGC MPK4 MPK4_ARATH 7W5CA 2.201 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo ANP ATPlike 18 - 372 0 None None Mitogen-activated protein kinase 4 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3UIMA 2.2 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii ANP ATPlike 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6A 1.898 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6B 1.898 Inactive DFGin‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXA 2.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYA 2.28 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYB 2.28 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVA 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVB 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWA 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWB 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMB 2.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC GRK1 GRK1_BOVIN 3T8OA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 532 0 None L166K Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 5 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4ZA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51A 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51B 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9D 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW5G 3.8 Inactive DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW8G 3.5 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 329 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW9G 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1Q24A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 TPO198,SEP339 V124A,L174M cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW7G 6.0 Inactive None‑None out-none in-out nonTYR APEdihe_aaini APEdist_iiio ANP ATPlike 13 - 351 0 None None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
TYR LET23 LET23_CAEEL 5WNOA 2.386 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nooai APEdist_aaao ANP ATPlike 876 - 1190 0 None None Receptor tyrosine-protein kinase let-23 Caenorhabditis elegans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 4 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CK1 HRR25 Q6FS46_CANGA 4XH0A 1.99 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 397 0 None K38R non-specific serine/threonine protein kinase Candida glabrata
CK1 HRR25 Q6FS46_CANGA 4XHGA 2.15 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iioo ADP ATPlike 2 - 397 0 None K38R non-specific serine/threonine protein kinase Candida glabrata
CMGC CDK7 G0SFC6_CHATD 6Z4XB 2.98 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 78 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
CMGC CDK7 G0SFC6_CHATD 6Z4XE 2.98 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 77 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
AGC PRKACA KAPCA_CRIGR 6EH2A 1.76 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EM6A 1.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EM7A 1.238 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EMAA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ESAA 1.307 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y8CA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CMGC CK2 Q5KF69_CRYD1 6ISEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CK2 Q5KF69_CRYD1 6ISEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CKA1 J9VNH4_CRYN9 6KO6B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 334 0 None None Casein kinase II subunit alpha Cryptococcus neoformans
CAMK CDPK1 A3FQ16_CRYPI 3IGOA 2.25 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 4Y5QA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo AMP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9D8SA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AMP ATPlike 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK3 Q5CS01_CRYPI 3LIJA 1.9 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 42 - 516 0 None None Calcium-dependent protein kinase 1 Cryptosporidium parvum
CAMK CDPK4-2 Q5CZ29_CRYPI 3HKOA 1.8 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoi ANP ATPlike 126 - 452 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CMGC CDK Q5CRJ8_CRYPI 3NIZA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ADP ATPlike 1 - 293 0 None None Cyclin-dependent kinase 2 homolog Cryptosporidium parvum
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
CAMK PLK1 Q4KMI8_DANRE 3D5WA 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 310 0 TPO196 None Serine/threonine-protein kinase PLK Danio rerio
TKL ROCO4 ROCO4_DICDI 4F0FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1OA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
CAMK CAMKII KCC2A_DROME 5FG8A 1.955 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5H9BA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5HU3A 1.885 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 272 0 None D136N Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK OBSCN-1 OBSCN_DROME 8AK3A 1.9 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 3186 - 3477 0 None None Protein Obscurin Drosophila melanogaster
CMGC BSK JNK_DROME 5AWMA 1.79 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 7 - 362 0 None None Stress-activated protein kinase JNK Drosophila melanogaster
OTHER BUBR1 A1Z6I7_DROME 6JKMA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo ADP ATPlike 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
CAMK CDPK Q3HNM4_EIMTE 4YSJA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
CAMK CDPK Q3HNM4_EIMTE 4YSJB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
TYR PTK2 FAK1_CHICK 2J0LA 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao ANP ATPlike 411 - 686 0 PTR576,PTR577 None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 3DQWA 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWB 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWC 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 258 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWD 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 257 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXA 2.3 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXB 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC CDK A8BZ95_GIAIC 3GC0A 2.0 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoni APEdist_nooo AMP ATPlike 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
CMGC MAPK A0A3Q8ITZ9_LEIDO 4QNYA 2.257 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooo ANP ATPlike 4 - 350 0 None None Mitogen activated protein kinase, putative Leishmania donovani
CMGC MAPK A0A3Q8ITZ9_LEIDO 4QNYB 2.257 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooo ANP ATPlike 4 - 350 0 None None Mitogen activated protein kinase, putative Leishmania donovani
TKL LYK3 LYK3_MEDTR 9GFZA 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 302 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
AGC PRKACA KAPCA_MOUSE 6MM6C 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM6E 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7A 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7D 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM8C 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKND 2.75 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKOE 2.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKPE 2.85 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 17 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTB 3.5 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4O21A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E11A 3.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM5E 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3PVBA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1ATPE 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1BKXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1L3RE 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 2QCSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FJQE 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDBA 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG0E 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH5A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DINA 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 10 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPTE 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPUE 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7A 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7C 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7UJXE 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7V0GE 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 17 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DFXE 1.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6RA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2UA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2VA 1.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2WA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IACA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IADA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAFA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAIA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAKA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAYA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB0A 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB1A 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW4A 1.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW5A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW6A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6E21A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E0ZA 2.162 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E12A 2.796 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1JBPE 2.2 Inactive DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 10 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG3E 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198 R337A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3O7LB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 18 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FHIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 C200A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QAME 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 E209A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QALE 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 R281A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTA 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC RPS6KA3-1 KS6A3_MOUSE 3G51A 1.8 Inactive DFGin‑None none-none out-none nonTYR APEdihe_aanii APEdist_nnnn ANP ATPlike 47 - 346 0 None None Ribosomal protein S6 kinase alpha-3 Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B56B 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B57B 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABB 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK MELK MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZE 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZF 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZG 2.6 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZH 2.6 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
STE STK39 STK39_MOUSE 5D9HA 3.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo ATP ATPlike 65 - 363 0 None None STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5D9HB 3.1 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaioi APEdist_nnno ATP ATPlike 65 - 364 0 None None STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5DBXA 2.5 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooo ANP ATPlike 65 - 365 0 None T243D STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
STE STK39 STK39_MOUSE 5DBXB 2.5 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooo ANP ATPlike 65 - 364 0 None T243D STE20/SPS1-related proline-alanine-rich protein kinase Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNIA 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 9 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 1JPAA 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 892 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 1JPAB 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 891 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
TYR LYN LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
TYR SRC SRC_MOUSE 8XN8A 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 534 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
TYR SRC SRC_MOUSE 6F3FA 2.418 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 531 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PA 2.37 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_iooo ACP ATPlike 1 - 278 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PB 2.37 Inactive None‑None in-out none-out nonTYR APEdihe_aanno APEdist_onnn ACP ATPlike 2 - 277 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y0XA 1.74 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii ADP ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y12A 1.9 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii AGS ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
CAMK PHKG1 PHKG1_RABIT 2PHKA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 291 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1QL6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 292 0 None E183S Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1PHKA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 292 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUQC 3.22 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP ATPlike 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUWC 2.88 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 2Y4IC 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP ATPlike 37 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
OTHER FLS2 FLS2_ORYSJ 8JUPA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 861 - 1176 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER FLS2 FLS2_ORYSJ 8JUVA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 861 - 1178 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
CAMK CDPK1 CDPK1_PLABA 3Q5IA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 38 - 518 0 None None Calcium-dependent protein kinase 1 Plasmodium berghei
CMGC CK1 Q8IIR9_PLAF7 5XVUA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC CK1 Q8IIR9_PLAF7 5XVUB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC CK1 Q8IIR9_PLAF7 5XVUC 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 12 - 332 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
CMGC MAPK Q7KQK7_PLAF7 3NIEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 95 - 499 0 None None Mitogen-activated protein kinase Plasmodium falciparum
CMGC MAPK Q7KQK7_PLAF7 3NIEB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 95 - 505 0 None None Mitogen-activated protein kinase Plasmodium falciparum
CMGC PSTK1 Q8IL19_PLAF7 3LLTA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 535 - 875 0 None None Protein serine/threonine kinase-1 Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYB 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYG 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 157 - 559 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYH 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER PK7 O96214_PLAFA 2PMLX 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 316 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
AGC PKG KGP_PLAVS 5DZCA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 843 0 None None cGMP-dependent protein kinase Plasmodium vivax
CMGC MPS1 MPS1_PYROR 8ZTCA 2.26 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi AMP ATPlike 5 - 408 0 None None Mitogen-activated protein kinase MPS1 Pyricularia oryzae
AGC PRKACA KAPCA_RAT 3TNQB 3.097 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 18 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus
AGC PRKCB KPCB_RAT 3PFQA 4.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 101 - 668 0 TPO500,TPO642,SEP661 C71S,C217S,R622S Protein kinase C beta type Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S33A 1.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 355 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S32A 1.34 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4GT3A 1.68 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4GVAA 1.83 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 7UGBA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4S34A 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 1GOLA 2.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 2 - 358 0 None K52R Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQVA 2.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_oiii ANP ATPlike 4 - 354 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQXA 1.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 353 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 8RQWA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 354 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TA 2.01 Inactive DFGin‑BLBtrans na-na out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TB 2.01 Inactive DFGin‑BLBtrans na-na out-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
AGC CBK1 CBK1_YEAST 4LQSA 3.3 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 294 - 749 0 None D475A Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 5NCLA 3.15 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 266 - 756 0 None D475A Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 4LQPA 4.5 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 282 - 749 0 None D475A,T743E Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
AGC CBK1 CBK1_YEAST 4LQQA 3.6 Inactive None‑None none-none out-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 282 - 749 0 None D475A,T743E Serine/threonine-protein kinase CBK1 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 4PDSA 2.9 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 191 - 490 0 None A225S,D339A Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 4PDSB 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 191 - 494 0 None A225S,D339A Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZVB 3.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo ANP ATPlike 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZVA 3.1 Inactive DFGin‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 16 - 465 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4FI1A 2.09 Inactive None‑None out-na in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4JQEA 1.77 Inactive None‑None out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC CKA1 CSK21_YEAST 4MWHA 2.09 Inactive None‑None out-na in-out nonTYR APEdihe_aaioi APEdist_iiii ATP ATPlike 1 - 371 0 None None Casein kinase II subunit alpha Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9HA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9IA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9JA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None T180V,Y182F Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2B9FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ADP ATPlike 1 - 353 0 None None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2F9GA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 1 - 353 0 PTR182 None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
CMGC KIN28 KIN28_YEAST 6XI8A 3.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 6 - 303 0 TPO162 None Serine/threonine-protein kinase KIN28 Saccharomyces cerevisiae
CMGC KIN28 KIN28_YEAST 7KUEA 3.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 6 - 303 0 TPO162 None Serine/threonine-protein kinase KIN28 Saccharomyces cerevisiae
CMGC PHO85 PHO85_YEAST 2PMIA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo AGS ATPlike 19 - 302 0 None None Cyclin-dependent protein kinase PHO85 Saccharomyces cerevisiae
CMGC PHO85 PHO85_YEAST 4KRCA 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 2 - 302 0 None None Cyclin-dependent protein kinase PHO85 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q8YA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q97A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 143 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99B 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 142 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
TKL NCGRLOCUS634 A0ACD6BAX3_9POAL 8HO6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 305 0 TPO184,SEP187,TPO188 None ScRIPK kinase protein Saccharum hybrid cultivar
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSA 3.07 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSB 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 946 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
CK1 CKI1 CKI1_SCHPO 1CSNA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
OTHER None A0ACD6BAW3_SERSF 5HNVA 1.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1QA 1.602 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1SA 1.45 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ACP ATPlike 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1TA 1.55 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ADP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
AGC PRKACA KAPCA_PIG 1CDKA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
AGC PRKACA KAPCA_PIG 1CDKB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
CAMK CDPK1 Q9BJF5_TOXGO 4IEBA 2.05 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 507 0 None G128M non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK1 Q9BJF5_TOXGO 3HX4A 1.95 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 503 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK1 Q9BJF5_TOXGO 3KU2A 2.3 Inactive None‑None out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 44 - 507 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP9A 2.8 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AN2 ATPlike 121 - 568 0 SEP205,TPO530 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
CMGC TVAG125560 A2F9N1_TRIV3 9AV7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 318 0 None None non-specific serine/threonine protein kinase Trichomonas vaginalis
CAMK AURKBA AUKBA_XENLA 4C2WA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2WB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
OTHER YOPO Q93KQ6_YEREN 5CE3B 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 5CE3D 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
CMGC ACK2 CSK2A_MAIZE 1DAWA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5A 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5B 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5C 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5D 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1LP4A 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays