9AXY

BRAF (Serine/threonine-protein kinase B-raf)
MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1)
Group: STE TKL
Uniprot: BRAF_HUMAN MP2K1_HUMAN
Organism: Homo sapiens
Domain boundary: 68 - 361 457 - 716
Resolution: 3.6

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Inactive DFGin BLBplus out-out out-out A1AHE ANP Type3 Type1 40 - 383 0
A TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf Homo sapiens Inactive DFGin BLBplus out-out out-out ANP Type1 448 - 722 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       453        463        473        483 
gdssDDWEIP DGQITVGQRI GSGSFGTVYK GKWHGDVAVK 
       493        503        513        523 
MLNVTAPTPQ QLQAFKNEVG VLRKTRHVNI LLFMGYSTKP 
       533        543        553        563 
QLAIVTQWCE GSSLYHHLHI IETKFEMIKL IDIARQTAQG 
       573        583        593        603 
MDYLHAKSII HRDLKSNNIF LHEDLTVKIG DFGLATVKSR 
       613        623        633        643 
WSGSHQFEQL SGSILWMAPE VIRMQDKNPY SFQSDVYAFG 
       653        663        673        683 
IVLYELMTGQ LPYSNINNRD QIIFMVGRGY LSPDLSKVRS 
       693        703        713        723 
NCPKAMKRLM AECLKKKRDE RPLFPQILAS IELLARSLPk


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None