PDB: 8PR7 — CAMK AURKA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 1 50.0% 8PR7D
DFGinter None 1 50.0% 8PR7A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8PR7A 2.76 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 124 - 389 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A

PDB: 8PR7 — CAMK AURKA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 1 50.0% 8PR7D
DFGinter None 1 50.0% 8PR7A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8PR7A 2.76 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ADP ATPlike 124 - 389 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A Homo sapiens

PDB: 8PR7 — CAMK AURKA_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism