8PR7

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.76

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None out-out none-out ADP Type1 124 - 389 13
D Inactive DFGin BLBminus out-none none-out ADP Type1 126 - 388 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       130        140        150        160 
meskkRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA 
       170        180        190        200 
LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF 
       210        220        230        240 
HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL 
       250        260        270        280 
ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIANFGWsvh 
       290        300        310        320 
apssrrttlA GTLDYLPPEM IEGRMHDEKV DLWSLGVLCY 
       330        340        350        360 
EFLVGKPPFE AATYAETYKR ISRVEFAFPA FVTEGARDLI 
       370        380        390        400 
SRLLKHNPSQ RPMLREVLEH PWITANSSkp snaqnkesas 

kqs
Lower-case residues are disordered in structure.
Mutations: D274N,C290A,N332A,Q335A,T347A,D350A,C393A
Phosphorylation: None