TYR_LYN (Tyrosine-protein kinase Lyn)

Total number of chains: 4
Active chains: 2
Uniprot: LYN_HUMAN
Kinase Domain Residues: 247 - 499
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-P07948-K1A
DFGin ABAminus 1 25.0% 5XY1A
DFGin None 1 25.0% 3A4OX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P07948-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn
AF-P07948-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn
5XY1A 2.7 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn
3A4OX 3.0 Inactive DFGin‑None in-in in-out TYR APEdihe_ooiai APEdist_aaai STU Type1 238 - 505 0 None None Tyrosine-protein kinase Lyn

TYR_LYN (Tyrosine-protein kinase Lyn)

Total number of chains: 8
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 75.0% AF-P07948-K1A
DFGin ABAminus 1 12.5% 5XY1A
DFGin None 1 12.5% 3A4OX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
LYN_HUMAN AF-P07948-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn Homo sapiens
LYN_HUMAN AF-P07948-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn Homo sapiens
LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Homo sapiens
LYN_HUMAN 3A4OX 3.0 Inactive DFGin‑None in-in in-out TYR APEdihe_ooiai APEdist_aaai STU Type1 238 - 505 0 None None Tyrosine-protein kinase Lyn Homo sapiens
LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZV7A 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZV9A 2.76 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP2 Type1 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZVAA 2.6 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Mus musculus

TYR_LYN (Tyrosine-protein kinase Lyn)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 2ZVAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZV7A 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZV9A 2.76 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP2 Type1 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
LYN_MOUSE 2ZVAA 2.6 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Mus musculus