PDPK1 (3-phosphoinositide-dependent protein kinase 1)

Group: AGC
Uniprot: PDPK1_HUMAN
Domain boundary: 82 - 342


Total number of chains: 81
Spatial Dihedral Chains Representative
DFGin BLAminus 78 AF-O15530-K1A
DFGout BBAminus 2 3NAXA
DFGout None 1 3QC4B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
3ORXA 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 1
3ORXB 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 77 - 359 T148C X241 2
3ORXC 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 1
3ORXD 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 76 - 359 T148C X241 1
3ORXE 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 76 - 359 T148C X241 10
3ORXF 2.204 None DFGin BLAminus in-none in-in 1F8 Allosteric 75 - 359 T148C X241 10
3ORXG 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 10
3ORXH 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 10
8DQTA 1.31 Active DFGin BLAminus in-in in-in U35 U35 U35 Allosteric Allosteric Allosteric 70 - 359 Y288G,Q292A X241 0
3ORZA 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 74 - 359 T148C X241 9
3ORZB 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 73 - 359 T148C X241 8
3ORZC 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 74 - 359 T148C X241 9
3ORZD 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 73 - 359 T148C X241 8
3OTUA 2.101 Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front 77 - 359 T148C X241 5
AF-O15530-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 74 - 350 None None 0
1Z5MA 2.17 Active DFGin BLAminus in-in in-in LI8 Type1 74 - 359 None X241 10
2PE0A 2.35 Active DFGin BLAminus in-in in-in 39Z Type1 74 - 359 None X241 10
2PE1A 2.14 Active DFGin BLAminus in-in in-in 517 Type1 74 - 359 None X241 10
2PE2A 2.13 Active DFGin BLAminus in-in in-in 464 Type1 74 - 359 None X241 10
3NUSA 2.75 Active DFGin BLAminus in-in in-in JNZ Type1 73 - 358 None X241 9
3NUUA 1.98 Active DFGin BLAminus in-in in-in JOZ Type1 73 - 358 None X241 9
3NUYA 2.1 Active DFGin BLAminus in-in in-in JPZ Type1 73 - 358 None X241 9
1UU9A 1.95 Active DFGin BLAminus in-in in-in BI3 Type1 72 - 357 None X241 9
1H1WA 2.0 Active DFGin BLAminus in-in in-in ATP Type1 71 - 359 None X241 4
1UVRA 2.81 Active DFGin BLAminus in-in in-in BI8 Type1 71 - 359 None X241 4
3NUNA 2.2 Active DFGin BLAminus in-in in-in JMZ Type1 71 - 358 None X241 9
2XCHA 2.0 Active DFGin BLAminus in-in in-in CKG Type1 73 - 359 None X241 8
5HKMA 2.1 Active DFGin BLAminus in-in in-in 61Y Type1 76 - 358 None X241 10
5HNGA 3.01 Active DFGin BLAminus in-in in-in 62O Type1 71 - 359 None X241 8
5HO7A 3.0 Active DFGin BLAminus in-in in-in 63L Type1 71 - 359 None X241 8
5HO8A 2.7 Active DFGin BLAminus in-in in-in 63E Type1 71 - 358 None X241 9
1OKYA 2.3 Active DFGin BLAminus in-in in-in STU Type1 72 - 360 None X241 6
1OKZA 2.51 Active DFGin BLAminus in-in in-in UCN Type1 73 - 359 None X241 9
1UU3A 1.7 Active DFGin BLAminus in-in in-in LY4 Type1 73 - 360 None X241 10
1UU7A 1.9 Active DFGin BLAminus in-in in-in BI2 Type1 73 - 359 None X241 5
1UU8A 2.5 Active DFGin BLAminus in-in in-in BI1 Type1 72 - 358 None X241 8
3NAYA 2.6 Active DFGin BLAminus in-in in-in MP6 Type1 76 - 362 None X241 8
3NAYB 2.6 Active DFGin BLAminus in-in in-in MP6 Type1 76 - 362 None X241 8
3RWPA 1.92 Active DFGin BLAminus in-in in-in ABQ Type1 73 - 359 None X241 9
3RWQA 2.55 Active DFGin BLAminus in-in in-in 3RW Type1 72 - 359 None X241 4
3SC1A 2.7 Active DFGin BLAminus in-in in-in 3S1 Type1 73 - 359 None X241 8
3H9OA 2.3 Active DFGin BLAminus in-in in-in 9BD Type1 75 - 359 None X241 9
2R7BA 2.7 Active DFGin BLAminus in-in in-in 253 Type1 75 - 359 None X241 10
3IONA 2.4 Active DFGin BLAminus in-in in-in 8H1 Type1 75 - 359 None None 11
3IOPA 2.2 Active DFGin BLAminus in-in in-in 8I1 Type1 75 - 359 None X241 9
3QCQA 2.501 Active DFGin BLAminus in-in in-in 3Q0 Type1 73 - 358 None X241 9
3QCSA 2.487 Active DFGin BLAminus in-in in-in 3Q1 Type1 73 - 358 None X241 9
2BIYA 1.95 Active DFGin BLAminus in-in in-in ATP Type1 72 - 359 S241A None 0
3HRCA 1.91 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 Y288G,Q292A X241 4
3RCJA 1.7 Active DFGin BLAminus in-in in-in 3RC Type1 77 - 358 Y288G,Q292A X241 0
4RRVA 1.412 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 Y288G,Q292A X241 0
5ACKA 1.24 Active DFGin BLAminus in-in in-in ATP Type1 73 - 359 Y288G,Q292A X241 0
5LVLA 1.4 Active DFGin BLAminus in-in in-in 537 Type1 74 - 359 Y288G,Q292A X241 0
5LVMA 1.26 Active DFGin BLAminus in-in in-in ADE Type1 76 - 359 Y288G,Q292A X241 0
5LVNA 1.379 Active DFGin BLAminus in-in in-in ADN Type1 75 - 359 Y288G,Q292A X241 0
5LVPA 2.5 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 Y288G,Q292A X241 9
5LVPB 2.5 Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 Y288G,Q292A X241 9
5LVPC 2.5 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 Y288G,Q292A X241 9
5LVPD 2.5 Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 Y288G,Q292A X241 9
4CT2A 1.25 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A X241 0
3PWYA 3.5 Active DFGin BLAminus in-in in-in SYP Type1 71 - 359 E166C,C260S None 8
5MRDA 1.41 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C X241 0
2XCKA 2.3 Active DFGin BLAminus in-in in-in MH4 Type1 76 - 359 None X241 8
3HRFA 1.9 Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
4A06A 2.0 Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
4AW0A 1.43 Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
4AW1A 1.68 Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric 66 - 359 Y288G,Q292A X241 5
4RQKA 1.55 Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric 74 - 359 Y288G,Q292A X241 0
4RQVA 1.502 Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric 71 - 359 Y288G,Q292A X241 0
5LVOA 1.09 Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric 73 - 359 Y288G,Q292A X241 0
4CT1A 1.85 None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric 76 - 359 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A X241 0
4XX9A 1.4 Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric 71 - 359 Y288G,Q292A X241 0
4A07A 1.85 Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric 75 - 359 Y288G,Q292A X241 0
3QCXA 2.3 Active DFGin BLAminus in-in in-in 3Q2 Type1.5_Back 73 - 358 None X241 9
3QCYA 2.2 Active DFGin BLAminus in-in in-in 3Q3 Type1.5_Front 73 - 358 None X241 11
3QD0A 1.99 Active DFGin BLAminus in-in in-in 3Q4 Type1.5_Front 73 - 358 None X241 12
3QD3A 2.0 Active DFGin BLAminus in-in in-in 3Q5 Type1.5_Front 71 - 358 None X241 9
3QD4A 2.3 Active DFGin BLAminus in-in in-in 3Q6 Type1.5_Front 71 - 358 None X241 12
3NAXA 1.75 Inactive DFGout BBAminus out-out in-none MP7 Type2 76 - 360 None None 7
3QC4A 1.8 Inactive DFGout BBAminus out-out in-in MP7 Type2 76 - 359 E303A,K304A X241 7
3QC4B 1.8 Inactive DFGout None out-out in-in MP7 Type2 51 - 359 E303A,K304A X241 7

PDPK1 (3-phosphoinositide-dependent protein kinase 1)

Group: AGC
Total number of chains: 81
Spatial Dihedral Chains Representative
DFGin BLAminus 78 AF-O15530-K1A
DFGout BBAminus 2 3NAXA
DFGout None 1 3QC4B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens PDPK1_HUMAN 3ORXA 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 1
Homo sapiens PDPK1_HUMAN 3ORXB 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 77 - 359 T148C X241 2
Homo sapiens PDPK1_HUMAN 3ORXC 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 1
Homo sapiens PDPK1_HUMAN 3ORXD 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 76 - 359 T148C X241 1
Homo sapiens PDPK1_HUMAN 3ORXE 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 76 - 359 T148C X241 10
Homo sapiens PDPK1_HUMAN 3ORXF 2.204 None DFGin BLAminus in-none in-in 1F8 Allosteric 75 - 359 T148C X241 10
Homo sapiens PDPK1_HUMAN 3ORXG 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 10
Homo sapiens PDPK1_HUMAN 3ORXH 2.204 Active DFGin BLAminus in-in in-in 1F8 Allosteric 75 - 359 T148C X241 10
Homo sapiens PDPK1_HUMAN 8DQTA 1.31 Active DFGin BLAminus in-in in-in U35 U35 U35 Allosteric Allosteric Allosteric 70 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 3ORZA 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 74 - 359 T148C X241 9
Homo sapiens PDPK1_HUMAN 3ORZB 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 73 - 359 T148C X241 8
Homo sapiens PDPK1_HUMAN 3ORZC 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 74 - 359 T148C X241 9
Homo sapiens PDPK1_HUMAN 3ORZD 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1 73 - 359 T148C X241 8
Homo sapiens PDPK1_HUMAN 3OTUA 2.101 Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front 77 - 359 T148C X241 5
Homo sapiens PDPK1_HUMAN AF-O15530-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 74 - 350 None None 0
Homo sapiens PDPK1_HUMAN 1Z5MA 2.17 Active DFGin BLAminus in-in in-in LI8 Type1 74 - 359 None X241 10
Homo sapiens PDPK1_HUMAN 2PE0A 2.35 Active DFGin BLAminus in-in in-in 39Z Type1 74 - 359 None X241 10
Homo sapiens PDPK1_HUMAN 2PE1A 2.14 Active DFGin BLAminus in-in in-in 517 Type1 74 - 359 None X241 10
Homo sapiens PDPK1_HUMAN 2PE2A 2.13 Active DFGin BLAminus in-in in-in 464 Type1 74 - 359 None X241 10
Homo sapiens PDPK1_HUMAN 3NUSA 2.75 Active DFGin BLAminus in-in in-in JNZ Type1 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 3NUUA 1.98 Active DFGin BLAminus in-in in-in JOZ Type1 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 3NUYA 2.1 Active DFGin BLAminus in-in in-in JPZ Type1 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 1UU9A 1.95 Active DFGin BLAminus in-in in-in BI3 Type1 72 - 357 None X241 9
Homo sapiens PDPK1_HUMAN 1H1WA 2.0 Active DFGin BLAminus in-in in-in ATP Type1 71 - 359 None X241 4
Homo sapiens PDPK1_HUMAN 1UVRA 2.81 Active DFGin BLAminus in-in in-in BI8 Type1 71 - 359 None X241 4
Homo sapiens PDPK1_HUMAN 3NUNA 2.2 Active DFGin BLAminus in-in in-in JMZ Type1 71 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 2XCHA 2.0 Active DFGin BLAminus in-in in-in CKG Type1 73 - 359 None X241 8
Homo sapiens PDPK1_HUMAN 5HKMA 2.1 Active DFGin BLAminus in-in in-in 61Y Type1 76 - 358 None X241 10
Homo sapiens PDPK1_HUMAN 5HNGA 3.01 Active DFGin BLAminus in-in in-in 62O Type1 71 - 359 None X241 8
Homo sapiens PDPK1_HUMAN 5HO7A 3.0 Active DFGin BLAminus in-in in-in 63L Type1 71 - 359 None X241 8
Homo sapiens PDPK1_HUMAN 5HO8A 2.7 Active DFGin BLAminus in-in in-in 63E Type1 71 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 1OKYA 2.3 Active DFGin BLAminus in-in in-in STU Type1 72 - 360 None X241 6
Homo sapiens PDPK1_HUMAN 1OKZA 2.51 Active DFGin BLAminus in-in in-in UCN Type1 73 - 359 None X241 9
Homo sapiens PDPK1_HUMAN 1UU3A 1.7 Active DFGin BLAminus in-in in-in LY4 Type1 73 - 360 None X241 10
Homo sapiens PDPK1_HUMAN 1UU7A 1.9 Active DFGin BLAminus in-in in-in BI2 Type1 73 - 359 None X241 5
Homo sapiens PDPK1_HUMAN 1UU8A 2.5 Active DFGin BLAminus in-in in-in BI1 Type1 72 - 358 None X241 8
Homo sapiens PDPK1_HUMAN 3NAYA 2.6 Active DFGin BLAminus in-in in-in MP6 Type1 76 - 362 None X241 8
Homo sapiens PDPK1_HUMAN 3NAYB 2.6 Active DFGin BLAminus in-in in-in MP6 Type1 76 - 362 None X241 8
Homo sapiens PDPK1_HUMAN 3RWPA 1.92 Active DFGin BLAminus in-in in-in ABQ Type1 73 - 359 None X241 9
Homo sapiens PDPK1_HUMAN 3RWQA 2.55 Active DFGin BLAminus in-in in-in 3RW Type1 72 - 359 None X241 4
Homo sapiens PDPK1_HUMAN 3SC1A 2.7 Active DFGin BLAminus in-in in-in 3S1 Type1 73 - 359 None X241 8
Homo sapiens PDPK1_HUMAN 3H9OA 2.3 Active DFGin BLAminus in-in in-in 9BD Type1 75 - 359 None X241 9
Homo sapiens PDPK1_HUMAN 2R7BA 2.7 Active DFGin BLAminus in-in in-in 253 Type1 75 - 359 None X241 10
Homo sapiens PDPK1_HUMAN 3IONA 2.4 Active DFGin BLAminus in-in in-in 8H1 Type1 75 - 359 None None 11
Homo sapiens PDPK1_HUMAN 3IOPA 2.2 Active DFGin BLAminus in-in in-in 8I1 Type1 75 - 359 None X241 9
Homo sapiens PDPK1_HUMAN 3QCQA 2.501 Active DFGin BLAminus in-in in-in 3Q0 Type1 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 3QCSA 2.487 Active DFGin BLAminus in-in in-in 3Q1 Type1 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 2BIYA 1.95 Active DFGin BLAminus in-in in-in ATP Type1 72 - 359 S241A None 0
Homo sapiens PDPK1_HUMAN 3HRCA 1.91 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 Y288G,Q292A X241 4
Homo sapiens PDPK1_HUMAN 3RCJA 1.7 Active DFGin BLAminus in-in in-in 3RC Type1 77 - 358 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4RRVA 1.412 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5ACKA 1.24 Active DFGin BLAminus in-in in-in ATP Type1 73 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5LVLA 1.4 Active DFGin BLAminus in-in in-in 537 Type1 74 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5LVMA 1.26 Active DFGin BLAminus in-in in-in ADE Type1 76 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5LVNA 1.379 Active DFGin BLAminus in-in in-in ADN Type1 75 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5LVPA 2.5 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 Y288G,Q292A X241 9
Homo sapiens PDPK1_HUMAN 5LVPB 2.5 Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 Y288G,Q292A X241 9
Homo sapiens PDPK1_HUMAN 5LVPC 2.5 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 Y288G,Q292A X241 9
Homo sapiens PDPK1_HUMAN 5LVPD 2.5 Active DFGin BLAminus in-in in-in ATP Type1 74 - 359 Y288G,Q292A X241 9
Homo sapiens PDPK1_HUMAN 4CT2A 1.25 Active DFGin BLAminus in-in in-in ATP Type1 75 - 359 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 3PWYA 3.5 Active DFGin BLAminus in-in in-in SYP Type1 71 - 359 E166C,C260S None 8
Homo sapiens PDPK1_HUMAN 5MRDA 1.41 Active DFGin BLAminus in-in in-in ATP Type1 76 - 359 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C X241 0
Homo sapiens PDPK1_HUMAN 2XCKA 2.3 Active DFGin BLAminus in-in in-in MH4 Type1 76 - 359 None X241 8
Homo sapiens PDPK1_HUMAN 3HRFA 1.9 Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4A06A 2.0 Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4AW0A 1.43 Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric 75 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4AW1A 1.68 Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric 66 - 359 Y288G,Q292A X241 5
Homo sapiens PDPK1_HUMAN 4RQKA 1.55 Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric 74 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4RQVA 1.502 Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric 71 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 5LVOA 1.09 Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric 73 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4CT1A 1.85 None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric 76 - 359 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4XX9A 1.4 Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric 71 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 4A07A 1.85 Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric 75 - 359 Y288G,Q292A X241 0
Homo sapiens PDPK1_HUMAN 3QCXA 2.3 Active DFGin BLAminus in-in in-in 3Q2 Type1.5_Back 73 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 3QCYA 2.2 Active DFGin BLAminus in-in in-in 3Q3 Type1.5_Front 73 - 358 None X241 11
Homo sapiens PDPK1_HUMAN 3QD0A 1.99 Active DFGin BLAminus in-in in-in 3Q4 Type1.5_Front 73 - 358 None X241 12
Homo sapiens PDPK1_HUMAN 3QD3A 2.0 Active DFGin BLAminus in-in in-in 3Q5 Type1.5_Front 71 - 358 None X241 9
Homo sapiens PDPK1_HUMAN 3QD4A 2.3 Active DFGin BLAminus in-in in-in 3Q6 Type1.5_Front 71 - 358 None X241 12
Homo sapiens PDPK1_HUMAN 3NAXA 1.75 Inactive DFGout BBAminus out-out in-none MP7 Type2 76 - 360 None None 7
Homo sapiens PDPK1_HUMAN 3QC4A 1.8 Inactive DFGout BBAminus out-out in-in MP7 Type2 76 - 359 E303A,K304A X241 7
Homo sapiens PDPK1_HUMAN 3QC4B 1.8 Inactive DFGout None out-out in-in MP7 Type2 51 - 359 E303A,K304A X241 7

PDPK1 (3-phosphoinositide-dependent protein kinase 1)

No non-human structures known.