AGC_PKN2 (Serine/threonine-protein kinase N2)

Total number of chains: 3
Active chains: 2
Uniprot: PKN2_HUMAN
Kinase Domain Residues: 657 - 916
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q16513-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q16513-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 649 - 924 0 None None Serine/threonine-protein kinase N2
AF-Q16513-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 649 - 924 0 None None Serine/threonine-protein kinase N2
4CRSA 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 646 - 984 0 SEP755,TPO816,TPO958 None Serine/threonine-protein kinase N2

AGC_PKN2 (Serine/threonine-protein kinase N2)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q16513-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PKN2_HUMAN AF-Q16513-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 649 - 924 0 None None Serine/threonine-protein kinase N2 Homo sapiens
PKN2_HUMAN AF-Q16513-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 649 - 924 0 None None Serine/threonine-protein kinase N2 Homo sapiens
PKN2_HUMAN 4CRSA 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 646 - 984 0 SEP755,TPO816,TPO958 None Serine/threonine-protein kinase N2 Homo sapiens

AGC_PKN2 (Serine/threonine-protein kinase N2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism