All / BLAplus / All

Total number of chains: 303
Active chains: 0
Total number of genes: 31
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 303 100.0% 8KH8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC MASTL GWL_HUMAN 5LOHA 3.1 Inactive DFGin‑BLAplus none-none out-out nonTYR APEdihe_aanon APEdist_nnno STU Type1 30 - 854 0 None None Serine/threonine-protein kinase greatwall
AGC PKN1 PKN1_HUMAN 4OTHA 1.8 Inactive DFGin‑BLAplus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn DRN Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1
AGC PKN1 PKN1_HUMAN 4OTIA 1.93 Inactive DFGin‑BLAplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn MI1 Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1
AGC RPS6KA1-1 KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
CAMK AURKA AURKA_HUMAN 4J8MA 1.853 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CJ5 Type1 125 - 390 0 None T287D Aurora kinase A
CAMK CHEK2 CHK2_HUMAN 3I6UA 3.0 Inactive DFGin‑BLAplus out-none out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 89 - 501 0 None K249R Serine/threonine-protein kinase Chk2
CMGC CDK4 CDK4_HUMAN 3G33A 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 295 0 None None Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 3G33C 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 5 - 295 0 None None Cyclin-dependent kinase 4
CMGC CDK7 CDK7_HUMAN 8P4ZA 2.75 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno WZ8 Type1 11 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK8 CDK8_HUMAN 8TQ2A 3.8 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 8TQCA 3.8 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 8TQWA 8.2 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDKL2 CDKL2_HUMAN 4BBMB 2.0 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaooi APEdist_iooo TC0 Type1 1 - 308 0 None T159D,Y161E Cyclin-dependent kinase-like 2
CMGC MAPK14 MK14_HUMAN 3HUBA 2.25 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 469 Type1 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3UVPA 2.4 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 048 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3UVQA 2.2 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn FS8 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER TTK TTK_HUMAN 3H9FA 2.6 Inactive DFGin‑BLAplus in-none out-out nonTYR APEdihe_aaoni APEdist_nnno 92M Type1 519 - 794 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
STE MAP2K7 MP2K7_HUMAN 7OVIA 1.95 Inactive DFGin‑BLAplus na-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2GI Type1.5_Front 102 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE PAK1 PAK1_HUMAN 1F3MC 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 1F3MD 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZY6B 2.15 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 4T6 Type1 255 - 542 0 None D389N Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9N4UB 1.77 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno A1BV8 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK2 PAK2_HUMAN 9LBGB 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aanoo APEdist_nnnn MLT Allosteric 91 - 522 0 None K278R Serine/threonine-protein kinase PAK 2
STE PAK2 PAK2_HUMAN 9LBGA 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 84 - 522 0 None K278R Serine/threonine-protein kinase PAK 2
STE PAK2 PAK2_HUMAN 9LBFA 2.62 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 86 - 522 0 None D368N Serine/threonine-protein kinase PAK 2
STE STK3 STK3_HUMAN 6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3
TKL BRAF BRAF_HUMAN 5JSMA 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMD 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2B 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2D 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UANB 3.9 Inactive DFGin‑BLAplus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 449 - 750 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9BFBA 1.92 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo A1AN9 Type1 448 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9BP8A 1.73 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo A1AQY Type1 449 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5FD2B 2.89 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 5XJ Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYUA 4.07 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1AEN Type1 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL IRAK4 IRAK4_HUMAN 9R9KC 1.87 Inactive DFGin‑BLAplus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A1JDQ Type1 164 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL MAP3K20 M3K20_HUMAN 5HESB 2.14 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 032 Type1 7 - 298 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWB 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWC 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TYR BTK BTK_HUMAN 1K2PA 2.1 Inactive DFGin‑BLAplus out-out in-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3K54A 1.94 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_nniai APEdist_aaao 1N1 Type1 392 - 658 0 None Y551E Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PIZA 2.21 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao 03C Type1 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PJ1A 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao LHL, LHL Type1, Allosteric 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR EGFR EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDPA 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XGMA 2.952 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao 85X Type1 696 - 1019 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JRJA 2.943 Inactive DFGin‑BLAplus in-out in-none TYR APEdihe_nnnai APEdist_aaan C6O Type1 696 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5Y25A 3.102 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 8LU Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDRA 2.6 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5N4 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM5A 2.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5Q2 Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus out-none none-out TYR APEdihe_nniai APEdist_aaao N7K Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5N3 Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor
TYR FGFR1 FGFR1_HUMAN 4RWIA 2.292 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWIB 2.292 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGKA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGKB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWYA 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 462 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWYB 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao No_ligand No_ligand 459 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KY2A 2.7 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KY2B 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWLA 2.193 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFE 2.58 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iooai APEdist_aaao No_ligand No_ligand 466 - 761 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM7A 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 764 0 None V561M Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM7B 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None V561M Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWKA 2.982 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1 458 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4ZSAA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4ZSAB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 462 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5Z0SA 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5Z0SB 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6ITJA 1.994 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AXU Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6ITJB 1.994 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao AXU Type1 459 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5A 2.939 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 465 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5B 2.939 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F63A 2.55 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F63B 2.55 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64A 2.05 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64B 2.05 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKAA 2.19 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKSA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 465 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKSB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWBA 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWBB 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 459 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWCA 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWCB 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 459 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O49A 1.91 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O49B 1.91 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O4AA 2.01 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 464 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O4AB 2.01 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZDAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZDBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZFAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 465 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZFBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1AGWA 2.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1AGWB 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGIA 2.5 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM6A 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM6B 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UQ0A 2.3 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UQ0B 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3JS2A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3JS2B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 459 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLC 2.8 Inactive DFGin‑BLAplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 766 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHCA 1.88 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHCB 1.88 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHIA 1.76 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHIB 1.76 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A46A 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 464 - 766 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A46B 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 766 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oooai APEdist_aaao GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnnao APEdist_aaan 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 8E1XA 2.68 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao U9P Type1 468 - 762 0 PTR561,PTR586 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8E1XB 2.68 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao U9P Type1 467 - 765 0 PTR561,PTR586 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8STGA 3.79 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_niiai APEdist_aaai WCJ Type1 461 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U3NA 3.25 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai A1ENT Type1 461 - 764 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_niiai APEdist_aaai UIM Type1.5_Back 460 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR3 FGFR3_HUMAN 6PNXA 2.199 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 456 - 757 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXB 2.199 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 455 - 756 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTA 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nnoai APEdist_aaao MLT, MLT, WGF Allosteric, Allosteric, Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9D1XA 1.6 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1A6M Type1 461 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7A 2.53 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 451 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7B 2.53 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7C 2.53 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVA 2.348 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVB 2.348 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao WIQ Type1.5_Back 455 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVC 2.348 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTB 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nooai APEdist_aaao WGF Type1.5_Front 457 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTC 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nooai APEdist_aaao WGF Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR4 FGFR4_HUMAN 4QQJA 1.682 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 454 - 752 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQTA 1.501 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYGA 2.4 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 447 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCXA 2.175 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBXA 2.233 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None V550M,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCWA 2.317 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBPA 2.243 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH8A 1.49 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 453 - 751 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 9K0IA 2.236 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao A1EEW Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 9K0JA 2.068 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EEX Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8W5CA 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8W5CB 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7VJLA 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 7IF Type1 454 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7VJLB 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 7IF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NUDA 2.5 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_niiai APEdist_aaao 99K Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYIA 3.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nniai APEdist_aaao 38O Type1 447 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCTA 2.106 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBOA 2.307 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YC1A 2.535 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IIQ Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YC3A 1.987 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IIW Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH6A 1.62 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVI Type1 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A 1.52 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 454 - 751 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6IUOA 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao AWX Type1 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6IUPA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AX0 Type1 452 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR ITK ITK_HUMAN 3MIYB 1.67 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan B49 Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF1A 2.113 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF1B 2.113 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nniai APEdist_aaao 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4RFMA 2.1 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3P6 Type1 357 - 618 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOA 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOB 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOD 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G6K Type1 357 - 618 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4L7SA 2.03 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4L7SB 2.03 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF0A 2.67 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PP9A 2.58 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PP9B 2.58 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4QD6A 2.45 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGWA 2.1 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao PQC Type1 358 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGYA 2.1 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan PQC Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5JA 2.59 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0F2 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LA 1.86 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LB 1.86 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LC 1.86 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_nnoai APEdist_aaao 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LD 1.86 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8TA 2.0 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8TB 2.0 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8WA 2.27 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8WB 2.27 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOC 2.18 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao G6K, G5K Type1, Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR KDR VGFR2_HUMAN 2P2HA 1.95 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nooai APEdist_aaao 994 Type1 815 - 1172 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR MERTK MERTK_HUMAN 7M5ZB 3.06 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 574 - 862 0 None None Tyrosine-protein kinase Mer
TYR PDGFRA PGFRA_HUMAN 6JOIA 3.1 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 569 - 973 0 None T674I Platelet-derived growth factor receptor alpha
TYR ZAP70 ZAP70_HUMAN 2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70
TYR ZAP70 ZAP70_HUMAN 4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70

All / BLAplus / All

Total number of chains: 316
Active chains: 0
Total number of genes: 37
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 316 100.0% 8KH8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER ZRK1 ZRK1_ARATH 6J5WB 3.7 Inactive DFGin‑BLAplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 15 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
TKL SYMRK E6YC17_ARAHY 6M0UA 2.29 Inactive DFGin‑BLAplus out-na none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 582 - 881 0 None K625E Nodulation receptor kinase Arachis hypogaea
TYR SRC SRC_CHICK 6L8LA 2.888 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LB 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 263 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LC 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LD 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 262 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC MASTL GWL_HUMAN 5LOHA 3.1 Inactive DFGin‑BLAplus none-none out-out nonTYR APEdihe_aanon APEdist_nnno STU Type1 30 - 854 0 None None Serine/threonine-protein kinase greatwall Homo sapiens
AGC PKN1 PKN1_HUMAN 4OTHA 1.8 Inactive DFGin‑BLAplus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn DRN Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1 Homo sapiens
AGC PKN1 PKN1_HUMAN 4OTIA 1.93 Inactive DFGin‑BLAplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn MI1 Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1 Homo sapiens
AGC RPS6KA1-1 KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo ANP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK AURKA AURKA_HUMAN 4J8MA 1.853 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CJ5 Type1 125 - 390 0 None T287D Aurora kinase A Homo sapiens
CAMK CHEK2 CHK2_HUMAN 3I6UA 3.0 Inactive DFGin‑BLAplus out-none out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 89 - 501 0 None K249R Serine/threonine-protein kinase Chk2 Homo sapiens
CMGC CDK4 CDK4_HUMAN 3G33A 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 295 0 None None Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 3G33C 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 5 - 295 0 None None Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8P4ZA 2.75 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno WZ8 Type1 11 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK8 CDK8_HUMAN 8TQ2A 3.8 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 8TQCA 3.8 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 8TQWA 8.2 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDKL2 CDKL2_HUMAN 4BBMB 2.0 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaooi APEdist_iooo TC0 Type1 1 - 308 0 None T159D,Y161E Cyclin-dependent kinase-like 2 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HUBA 2.25 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 469 Type1 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3UVPA 2.4 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 048 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3UVQA 2.2 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn FS8 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER TTK TTK_HUMAN 3H9FA 2.6 Inactive DFGin‑BLAplus in-none out-out nonTYR APEdihe_aaoni APEdist_nnno 92M Type1 519 - 794 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
STE MAP2K7 MP2K7_HUMAN 7OVIA 1.95 Inactive DFGin‑BLAplus na-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2GI Type1.5_Front 102 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE PAK1 PAK1_HUMAN 1F3MC 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 1F3MD 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZY6B 2.15 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 4T6 Type1 255 - 542 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9N4UB 1.77 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno A1BV8 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK2 PAK2_HUMAN 9LBGB 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aanoo APEdist_nnnn MLT Allosteric 91 - 522 0 None K278R Serine/threonine-protein kinase PAK 2 Homo sapiens
STE PAK2 PAK2_HUMAN 9LBGA 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 84 - 522 0 None K278R Serine/threonine-protein kinase PAK 2 Homo sapiens
STE PAK2 PAK2_HUMAN 9LBFA 2.62 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 86 - 522 0 None D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
STE STK3 STK3_HUMAN 6AO5A 2.955 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioo APEdist_nooo ANP ATPlike 28 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMA 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMD 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2B 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2D 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UANB 3.9 Inactive DFGin‑BLAplus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 449 - 750 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9BFBA 1.92 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo A1AN9 Type1 448 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9BP8A 1.73 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo A1AQY Type1 449 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5FD2B 2.89 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 5XJ Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYUA 4.07 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1AEN Type1 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9KC 1.87 Inactive DFGin‑BLAplus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A1JDQ Type1 164 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5HESB 2.14 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 032 Type1 7 - 298 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWB 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWC 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TYR BTK BTK_HUMAN 1K2PA 2.1 Inactive DFGin‑BLAplus out-out in-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3K54A 1.94 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_nniai APEdist_aaao 1N1 Type1 392 - 658 0 None Y551E Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3PIZA 2.21 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao 03C Type1 391 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3PJ1A 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao LHL, LHL Type1, Allosteric 391 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR EGFR EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EDPA 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5XGMA 2.952 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao 85X Type1 696 - 1019 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6JRJA 2.943 Inactive DFGin‑BLAplus in-out in-none TYR APEdihe_nnnai APEdist_aaan C6O Type1 696 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5Y25A 3.102 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 8LU Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EDRA 2.6 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5N4 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EM5A 2.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5Q2 Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus out-none none-out TYR APEdihe_nniai APEdist_aaao N7K Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nniai APEdist_aaai 5N3 Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWIA 2.292 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWIB 2.292 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1FGKA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1FGKB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWYA 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 462 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWYB 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao No_ligand No_ligand 459 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3KY2A 2.7 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3KY2B 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWLA 2.193 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5FLFE 2.58 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iooai APEdist_aaao No_ligand No_ligand 466 - 761 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5AM7A 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 764 0 None V561M Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5AM7B 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None V561M Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWKA 2.982 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1 458 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4ZSAA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4ZSAB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 462 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5Z0SA 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5Z0SB 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6ITJA 1.994 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AXU Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6ITJB 1.994 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao AXU Type1 459 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9CD5A 2.939 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 465 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9CD5B 2.939 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4F63A 2.55 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4F63B 2.55 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4F64A 2.05 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4F64B 2.05 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NKAA 2.19 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NKSA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 465 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NKSB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWBA 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWBB 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 459 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWCA 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4UWCB 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 459 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5O49A 1.91 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5O49B 1.91 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5O4AA 2.01 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 464 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5O4AB 2.01 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZDAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZDBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZFAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 465 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7OZFBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1AGWA 2.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1AGWB 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1FGIA 2.5 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 1FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5AM6A 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5AM6B 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UQ0A 2.3 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UQ0B 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3JS2A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3JS2B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 459 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQLC 2.8 Inactive DFGin‑BLAplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 766 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9UHCA 1.88 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9UHCB 1.88 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9UHIA 1.76 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 9UHIB 1.76 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A46A 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 464 - 766 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A46B 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 766 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oooai APEdist_aaao GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnnao APEdist_aaan 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8E1XA 2.68 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao U9P Type1 468 - 762 0 PTR561,PTR586 None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8E1XB 2.68 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao U9P Type1 467 - 765 0 PTR561,PTR586 None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8STGA 3.79 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_niiai APEdist_aaai WCJ Type1 461 - 764 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 9U3NA 3.25 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai A1ENT Type1 461 - 764 0 None V564F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_niiai APEdist_aaai UIM Type1.5_Back 460 - 764 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 6PNXA 2.199 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 456 - 757 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 6PNXB 2.199 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 455 - 756 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDTA 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nnoai APEdist_aaao MLT, MLT, WGF Allosteric, Allosteric, Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 9D1XA 1.6 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1A6M Type1 461 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 9CD7A 2.53 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 451 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 9CD7B 2.53 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 9CD7C 2.53 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVA 2.348 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVB 2.348 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao WIQ Type1.5_Back 455 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVC 2.348 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDTB 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nooai APEdist_aaao WGF Type1.5_Front 457 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDTC 2.829 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nooai APEdist_aaao WGF Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQJA 1.682 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 454 - 752 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQTA 1.501 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4TYGA 2.4 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 447 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7WCXA 2.175 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7YBXA 2.233 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None V550M,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7WCWA 2.317 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7YBPA 2.243 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8KH8A 1.49 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 453 - 751 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 9K0IA 2.236 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao A1EEW Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 9K0JA 2.068 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EEX Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8W5CA 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8W5CB 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7VJLA 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 7IF Type1 454 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7VJLB 2.9 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 7IF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 5NUDA 2.5 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_niiai APEdist_aaao 99K Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4TYIA 3.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nniai APEdist_aaao 38O Type1 447 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7WCTA 2.106 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 90F Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7YBOA 2.307 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IH7 Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7YC1A 2.535 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IIQ Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7YC3A 1.987 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao IIW Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8KH6A 1.62 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVI Type1 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8KH7A 1.52 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 454 - 751 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6IUOA 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao AWX Type1 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6IUPA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AX0 Type1 452 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nniai APEdist_aaao XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR ITK ITK_HUMAN 3MIYB 1.67 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan B49 Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4MF1A 2.113 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4MF1B 2.113 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_nniai APEdist_aaao 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4RFMA 2.1 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3P6 Type1 357 - 618 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4KIOA 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4KIOB 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4KIOD 2.18 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan G6K Type1 357 - 618 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4L7SA 2.03 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4L7SB 2.03 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4MF0A 2.67 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PP9A 2.58 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PP9B 2.58 Inactive DFGin‑BLAplus in-out none-none TYR APEdihe_nnnai APEdist_aaan 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4QD6A 2.45 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3QGWA 2.1 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao PQC Type1 358 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3QGYA 2.1 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan PQC Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V5JA 2.59 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0F2 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V5LA 1.86 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V5LB 1.86 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V5LC 1.86 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_nnoai APEdist_aaao 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V5LD 1.86 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V8TA 2.0 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V8TB 2.0 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 477 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V8WA 2.27 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3V8WB 2.27 Inactive DFGin‑BLAplus out-none none-none TYR APEdihe_nnnai APEdist_aaan 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4KIOC 2.18 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao G6K, G5K Type1, Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR KDR VGFR2_HUMAN 2P2HA 1.95 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nooai APEdist_aaao 994 Type1 815 - 1172 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR MERTK MERTK_HUMAN 7M5ZB 3.06 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 574 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR PDGFRA PGFRA_HUMAN 6JOIA 3.1 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 569 - 973 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
TYR ZAP70 ZAP70_HUMAN 2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70 Homo sapiens
TYR ZAP70 ZAP70_HUMAN 4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70 Homo sapiens
CMGC MPK10 Q4QHJ8_LEIMA 3PG1A 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 5 - 360 0 None None Putative mitogen-activated protein kinase Leishmania major
CMGC MPK10 Q4QHJ8_LEIMA 3UIBA 2.65 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aaoni APEdist_nooo SB2 Type1 7 - 359 0 None None Putative mitogen-activated protein kinase Leishmania major
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER TBK1 TBK1_MOUSE 4JL9A 3.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno BX7 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 4JLCA 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno SU6 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER CDC7 CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae

All / BLAplus / All

Total number of chains: 13
Active chains: 0
Total number of genes: 7
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 13 100.0% 4JLCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER ZRK1 ZRK1_ARATH 6J5WB 3.7 Inactive DFGin‑BLAplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 15 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
TKL SYMRK E6YC17_ARAHY 6M0UA 2.29 Inactive DFGin‑BLAplus out-na none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 582 - 881 0 None K625E Nodulation receptor kinase Arachis hypogaea
TYR SRC SRC_CHICK 6L8LA 2.888 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LB 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 263 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LC 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6L8LD 2.888 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao 1E8 Type1 262 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC MPK10 Q4QHJ8_LEIMA 3PG1A 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 5 - 360 0 None None Putative mitogen-activated protein kinase Leishmania major
CMGC MPK10 Q4QHJ8_LEIMA 3UIBA 2.65 Inactive DFGin‑BLAplus in-in none-out nonTYR APEdihe_aaoni APEdist_nooo SB2 Type1 7 - 359 0 None None Putative mitogen-activated protein kinase Leishmania major
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER TBK1 TBK1_MOUSE 4JL9A 3.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno BX7 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 4JLCA 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno SU6 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER CDC7 CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae