Protein kinases in complex with ATP

Total number of genes: 31
Total number of chains: 173
Spatial Dihedral Chains Representative
DFGin BLAminus 112 5LVOA
DFGin ABAminus 4 7T4TA
DFGin BLBplus 21 3DKCA
DFGin BLBtrans 6 1HCKA
DFGin None 12 5I4NA
DFGinter None 14 9D5IA
DFGout None 1 8FO9E
None None 3 4FG8B
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC GRK5 GRK5_HUMAN G protein-coupled receptor kinase 5 9CKRA 2.8 Active DFGin BLAminus in-in in-in ATP Type1
AGC GRK5 GRK5_HUMAN G protein-coupled receptor kinase 5 9CKSA 3.08 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 1H1WA 2.0 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 2BIYA 1.95 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRCA 1.91 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RRVA 1.412 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5ACKA 1.24 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPA 2.5 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPB 2.5 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPC 2.5 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPD 2.5 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT2A 1.25 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5MRDA 1.41 Active DFGin BLAminus in-in in-in ATP Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRFA 1.9 Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A06A 2.0 Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW0A 1.43 Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW1A 1.68 Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQKA 1.55 Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQVA 1.502 Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVOA 1.09 Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT1A 1.85 None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4XX9A 1.4 Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A07A 1.85 Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB8A 1.55 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB5A 1.641 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6NO7E 3.55 Inactive DFGin BLAminus in-out in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6NO7G 3.55 Inactive DFGin BLAminus in-out in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB7A 1.9 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB7B 1.9 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6BYRA 3.661 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6BYRC 3.661 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDCA 4.18 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDDA 6.3 Inactive DFGin BLAminus in-out out-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDEA 5.9 Inactive DFGin BLAminus in-out out-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB6A 2.1 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB6B 2.1 Active DFGin BLAminus in-in in-in ATP Type1
AGC PRKCI KPCI_HUMAN Protein kinase C iota type 3A8WA 2.1 Inactive DFGin BLAminus in-out in-in ATP Type1
AGC PRKCI KPCI_HUMAN Protein kinase C iota type 3A8WB 2.1 Inactive DFGin BLAminus in-out in-in ATP Type1
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TA 2.08 Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TB 2.08 Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DN3A 2.05 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1EA 2.798 Inactive DFGin BLAminus in-in in-out T0X ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT4A 2.86 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DOSA 2.98 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR2A 2.46 Inactive DFGin BLAminus in-in in-out 5E1 ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DNRA 1.95 Inactive DFGin BLAminus in-in in-out ATP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT3A 2.33 Inactive DFGin BLAminus in-in in-out ATP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DRDA 2.13 Inactive DFGin BLAminus in-in in-out ATP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL6A 3.0 None DFGin BLAminus in-out in-none ATP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBJA 2.901 Inactive DFGin None out-out in-out ATP 9QK Type1 Allosteric
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG7A 2.7 Active DFGin BLAminus in-in in-in ATP Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 Inactive DFGinter None out-out none-none ATP Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 Inactive DFGinter None out-none none-out ATP Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG8A 2.2 Inactive None None out-none none-none ATP Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG8B 2.2 Inactive None None out-none none-out ATP Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UIRA 3.1 Active DFGin BLAminus in-in in-in ATP Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UIRB 3.1 Active DFGin BLAminus in-in in-in ATP Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJPB 2.56 Active DFGin BLAminus in-in in-in ATP Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJTA 2.1 Inactive DFGin BLAminus out-out in-in ATP Type1
CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5RC 3.52 None DFGin BLAminus out-none out-in ATP Type1
CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TC 3.74 None DFGin BLAminus out-none out-in ATP Type1
CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TG 3.74 None DFGin BLAminus out-none out-in ATP Type1
CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TK 3.74 None DFGin BLAminus out-none out-in ATP Type1
CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TO 3.74 None DFGin BLAminus out-none out-in ATP Type1
CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7DA 2.6 Inactive DFGin BLAminus in-in in-out ATP Type1
CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7EA 2.85 Inactive DFGin BLAminus in-in in-out ATP Type1
CK1 TTBK1 TTBK1_HUMAN Tau-tubulin kinase 1 4BTJB 2.16 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOOA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOOC 2.1 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOMA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOMC 2.1 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FINA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FINC 2.3 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FQ1B 3.0 Inactive DFGin BLAminus in-out in-out ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1JSTA 2.6 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1JSTC 2.6 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CJMA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CJMC 2.3 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1GY3A 2.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1GY3C 2.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1QMZA 2.2 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1QMZC 2.2 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCHA 1.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCHC 1.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCIA 2.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCIC 2.7 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOQA 2.15 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOQC 2.15 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOJA 1.65 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOJC 1.65 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1HCKA 1.9 Inactive DFGin BLBtrans out-out out-out ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP5A 1.7 Inactive DFGin BLBtrans out-out out-out ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1B38A 2.0 Inactive DFGin BLBtrans out-out out-out ATP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1B39A 2.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2A 3.02 Inactive DFGin None out-out out-out ATP Type1
CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2B 3.02 Inactive DFGin None out-out out-out ATP Type1
CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2C 3.02 Inactive DFGin None out-out out-out ATP Type1
CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2D 3.02 Inactive DFGin None out-out out-out ATP Type1
CMGC CDK9 CDK9_HUMAN Cyclin-dependent kinase 9 3BLQA 2.9 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS8A 1.55 Active DFGin BLAminus in-in in-in J27 J27 J27 ATP Allosteric Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTRA 1.52 Active DFGin BLAminus in-in in-in AU8 AU8 AU8 ATP Allosteric Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHA 1.59 Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHB 1.59 Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7A 1.66 Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDB 1.66 Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7B 1.66 Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDA 1.66 Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVFA 1.63 Active DFGin BLAminus in-in in-in 54Z ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVFA 1.47 Active DFGin BLAminus in-in in-in 503 ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVGA 1.6 Active DFGin BLAminus in-in in-in E8K ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEKA 1.65 Active DFGin BLAminus in-in in-in LVL ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEMA 1.6 Active DFGin BLAminus in-in in-in LVF ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU6A 1.36 Active DFGin BLAminus in-in in-in ATP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYDA 1.404 Active DFGin BLAminus in-in in-in ATP KD6 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYRA 1.85 Active DFGin BLAminus in-in in-in ATP KF6 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AECA 1.09 Active DFGin BLAminus in-in in-in ATP LW3 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSPA 1.91 Active DFGin BLAminus in-in in-in ATP A9W Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSRA 1.57 Active DFGin BLAminus in-in in-in ATP AFK Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY2A 1.51 Active DFGin BLAminus in-in in-in ATP H4N H4N Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYOA 1.58 Active DFGin BLAminus in-in in-in ATP KEX KEX Type1 Allosteric Allosteric
OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMNA 2.7 Inactive DFGin ABAminus out-out out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCOA 4.4 Inactive DFGin BLBplus out-none out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCOB 4.4 Inactive DFGin BLBplus out-none out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCPA 4.1 Inactive DFGin BLBplus out-none out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCPB 4.1 Inactive DFGin BLBtrans out-none out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCSA 4.4 Inactive DFGin None out-none out-out ATP Type1
RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCSB 4.4 Inactive None None out-none out-out ATP Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN3A 2.1 Inactive DFGin BLBplus out-out out-out ATP 5Y0 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3OS3A 2.8 Inactive DFGin BLBplus out-out out-out ATP 3OS Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DV3A 2.3 Inactive DFGin BLBplus out-out out-out ATP MEK Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3PP1A 2.7 Inactive DFGin BLBplus out-out out-out ATP IZG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQBA 2.62 Inactive DFGin BLBplus out-out out-out ATP LUG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 1S9JA 2.4 Inactive DFGin BLBplus out-out out-out ATP BBM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DY7A 2.7 Inactive DFGin BLBplus out-out out-out ATP 1CX Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA 2.5 Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHA 2.0 Inactive DFGin BLBplus out-out out-none ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHB 2.0 Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHC 2.0 Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A 2.8 Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V01A 2.705 Inactive DFGin BLBplus out-out out-out 3V0 ATP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V04A 2.7 Inactive DFGin BLBplus out-out out-out V04 ATP Type3 Type1
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA 3.2 Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB 3.2 Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 3Q53A 2.09 None DFGin BLAminus out-none in-in ATP Type1
STE PAK4 PAK4_HUMAN Serine/threonine-protein kinase PAK 4 4XBRA 2.94 Inactive DFGin ABAminus in-in in-in ATP Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7HA 1.96 Inactive DFGin BLAminus in-out in-in ATP Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7HB 1.96 Inactive DFGin BLAminus out-out in-in ATP Type1
STE STRADA STRAA_HUMAN STE20-related kinase adapter protein alpha 3GNIB 2.35 None DFGin BLAminus in-none in-out ATP Type1
TKL ILK ILK_HUMAN Scaffold protein ILK 9D5IA 1.5 Inactive DFGinter None out-out out-out ATP Type1
TKL ILK ILK_HUMAN Scaffold protein ILK 3KMWA 2.0 Inactive DFGinter None out-out out-out ATP Type1
TKL ILK ILK_HUMAN Scaffold protein ILK 3REPA 1.8 Inactive DFGinter None out-out out-out ATP Type1
TKL KSR2 KSR2_HUMAN Kinase suppressor of Ras 2 2Y4IB 3.46 Inactive DFGin BLBplus out-none out-out ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9A 3.48 Active DFGin BLAminus in-in in-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9C 3.48 Active DFGin BLAminus in-in in-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 Inactive DFGinter None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9E 3.48 Inactive DFGout None out-out out-in ATP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8PO4B 1.621 Inactive DFGin BLBtrans out-out out-out ATP Type1
TYR INSR INSR_HUMAN Insulin receptor 3BU5A 2.1 Active DFGin BLAminus in-in in-in ATP Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5I4NA 1.54 Inactive DFGin None out-none out-out ATP Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4FVRA 2.0 Inactive DFGin None out-none out-out ATP Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4FVQA 1.75 Inactive DFGin None out-none out-out ATP Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8C08A 2.2 Inactive DFGin None in-none out-out ATP Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8C08B 2.2 Inactive DFGin None out-none out-out ATP Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 3DKCA 1.52 Inactive DFGin BLBplus out-out out-out ATP Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMA 2.187 Inactive DFGin None in-in none-out ATP Type1

Protein kinases in complex with ATP

Total number of genes: 48
Total number of chains: 235
Spatial Dihedral Chains Representative
DFGin BLAminus 153 5LVOA
DFGin ABAminus 4 7T4TA
DFGin BLBminus 3 7Z9TBBB
DFGin BLBplus 23 3DKCA
DFGin BLBtrans 8 1HCKA
DFGin None 24 5I4NA
DFGinter None 14 9D5IA
DFGout None 1 8FO9E
None None 5 4FI1A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPYA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDVA 1.97 None DFGin BLAminus in-none in-none ATP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDVB 1.97 None DFGin BLAminus in-none in-none ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3T8OA 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4WA 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4WB 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4XA 2.9 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4XB 2.9 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 9DW9G 2.8 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q24A 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIA 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIB 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIC 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYID 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIE 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIF 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIG 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIH 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJA 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJB 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJC 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJD 2.59 Inactive DFGin None out-none out-none ATP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EMAA 1.88 Active DFGin BLAminus in-in in-in ATP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Y8CA 1.76 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC GRK5 GRK5_HUMAN G protein-coupled receptor kinase 5 9CKRA 2.8 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC GRK5 GRK5_HUMAN G protein-coupled receptor kinase 5 9CKSA 3.08 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 1H1WA 2.0 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 2BIYA 1.95 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRCA 1.91 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RRVA 1.412 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5ACKA 1.24 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPA 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPB 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPC 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVPD 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT2A 1.25 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5MRDA 1.41 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRFA 1.9 Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A06A 2.0 Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW0A 1.43 Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW1A 1.68 Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQKA 1.55 Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQVA 1.502 Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVOA 1.09 Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT1A 1.85 None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4XX9A 1.4 Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A07A 1.85 Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB8A 1.55 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB5A 1.641 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6NO7E 3.55 Inactive DFGin BLAminus in-out in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6NO7G 3.55 Inactive DFGin BLAminus in-out in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB7A 1.9 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB7B 1.9 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6BYRA 3.661 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 6BYRC 3.661 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDCA 4.18 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDDA 6.3 Inactive DFGin BLAminus in-out out-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 9EDEA 5.9 Inactive DFGin BLAminus in-out out-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB6A 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 4WB6B 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens AGC PRKCI KPCI_HUMAN Protein kinase C iota type 3A8WA 2.1 Inactive DFGin BLAminus in-out in-in ATP Type1
Homo sapiens AGC PRKCI KPCI_HUMAN Protein kinase C iota type 3A8WB 2.1 Inactive DFGin BLAminus in-out in-in ATP Type1
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TA 2.08 Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TB 2.08 Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DN3A 2.05 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1EA 2.798 Inactive DFGin BLAminus in-in in-out T0X ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT4A 2.86 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DOSA 2.98 Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR2A 2.46 Inactive DFGin BLAminus in-in in-out 5E1 ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DNRA 1.95 Inactive DFGin BLAminus in-in in-out ATP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT3A 2.33 Inactive DFGin BLAminus in-in in-out ATP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DRDA 2.13 Inactive DFGin BLAminus in-in in-out ATP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL6A 3.0 None DFGin BLAminus in-out in-none ATP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBJA 2.901 Inactive DFGin None out-out in-out ATP 9QK Type1 Allosteric
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG7A 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 Inactive DFGinter None out-out none-none ATP Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 Inactive DFGinter None out-none none-out ATP Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG8A 2.2 Inactive None None out-none none-none ATP Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG8B 2.2 Inactive None None out-none none-out ATP Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UIRA 3.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UIRB 3.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJPB 2.56 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJTA 2.1 Inactive DFGin BLAminus out-out in-in ATP Type1
Homo sapiens CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5RC 3.52 None DFGin BLAminus out-none out-in ATP Type1
Homo sapiens CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TC 3.74 None DFGin BLAminus out-none out-in ATP Type1
Homo sapiens CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TG 3.74 None DFGin BLAminus out-none out-in ATP Type1
Homo sapiens CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TK 3.74 None DFGin BLAminus out-none out-in ATP Type1
Homo sapiens CAMK PHKG1 PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 8Z5TO 3.74 None DFGin BLAminus out-none out-in ATP Type1
Homo sapiens CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7DA 2.6 Inactive DFGin BLAminus in-in in-out ATP Type1
Homo sapiens CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7EA 2.85 Inactive DFGin BLAminus in-in in-out ATP Type1
Homo sapiens CK1 TTBK1 TTBK1_HUMAN Tau-tubulin kinase 1 4BTJB 2.16 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOOA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOOC 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOMA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOMC 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FINA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FINC 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1FQ1B 3.0 Inactive DFGin BLAminus in-out in-out ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1JSTA 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1JSTC 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CJMA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CJMC 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1GY3A 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1GY3C 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1QMZA 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1QMZC 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCHA 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCHC 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCIA 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2CCIC 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOQA 2.15 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOQC 2.15 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOJA 1.65 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EOJC 1.65 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1HCKA 1.9 Inactive DFGin BLBtrans out-out out-out ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP5A 1.7 Inactive DFGin BLBtrans out-out out-out ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1B38A 2.0 Inactive DFGin BLBtrans out-out out-out ATP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1B39A 2.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
Homo sapiens CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2A 3.02 Inactive DFGin None out-out out-out ATP Type1
Homo sapiens CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2B 3.02 Inactive DFGin None out-out out-out ATP Type1
Homo sapiens CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2C 3.02 Inactive DFGin None out-out out-out ATP Type1
Homo sapiens CMGC CDK7 CDK7_HUMAN Cyclin-dependent kinase 7 1UA2D 3.02 Inactive DFGin None out-out out-out ATP Type1
Homo sapiens CMGC CDK9 CDK9_HUMAN Cyclin-dependent kinase 9 3BLQA 2.9 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS8A 1.55 Active DFGin BLAminus in-in in-in J27 J27 J27 ATP Allosteric Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTRA 1.52 Active DFGin BLAminus in-in in-in AU8 AU8 AU8 ATP Allosteric Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHA 1.59 Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHB 1.59 Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7A 1.66 Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDB 1.66 Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7B 1.66 Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDA 1.66 Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVFA 1.63 Active DFGin BLAminus in-in in-in 54Z ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVFA 1.47 Active DFGin BLAminus in-in in-in 503 ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVGA 1.6 Active DFGin BLAminus in-in in-in E8K ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEKA 1.65 Active DFGin BLAminus in-in in-in LVL ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEMA 1.6 Active DFGin BLAminus in-in in-in LVF ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU6A 1.36 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYDA 1.404 Active DFGin BLAminus in-in in-in ATP KD6 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYRA 1.85 Active DFGin BLAminus in-in in-in ATP KF6 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AECA 1.09 Active DFGin BLAminus in-in in-in ATP LW3 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSPA 1.91 Active DFGin BLAminus in-in in-in ATP A9W Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSRA 1.57 Active DFGin BLAminus in-in in-in ATP AFK Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY2A 1.51 Active DFGin BLAminus in-in in-in ATP H4N H4N Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYOA 1.58 Active DFGin BLAminus in-in in-in ATP KEX KEX Type1 Allosteric Allosteric
Homo sapiens OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMNA 2.7 Inactive DFGin ABAminus out-out out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCOA 4.4 Inactive DFGin BLBplus out-none out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCOB 4.4 Inactive DFGin BLBplus out-none out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCPA 4.1 Inactive DFGin BLBplus out-none out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCPB 4.1 Inactive DFGin BLBtrans out-none out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCSA 4.4 Inactive DFGin None out-none out-out ATP Type1
Homo sapiens RGC NPR1 ANPRA_HUMAN Atrial natriuretic peptide receptor 1 9BCSB 4.4 Inactive None None out-none out-out ATP Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN3A 2.1 Inactive DFGin BLBplus out-out out-out ATP 5Y0 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3OS3A 2.8 Inactive DFGin BLBplus out-out out-out ATP 3OS Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DV3A 2.3 Inactive DFGin BLBplus out-out out-out ATP MEK Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3PP1A 2.7 Inactive DFGin BLBplus out-out out-out ATP IZG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQBA 2.62 Inactive DFGin BLBplus out-out out-out ATP LUG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 1S9JA 2.4 Inactive DFGin BLBplus out-out out-out ATP BBM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DY7A 2.7 Inactive DFGin BLBplus out-out out-out ATP 1CX Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA 2.5 Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHA 2.0 Inactive DFGin BLBplus out-out out-none ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHB 2.0 Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHC 2.0 Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A 2.8 Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V01A 2.705 Inactive DFGin BLBplus out-out out-out 3V0 ATP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V04A 2.7 Inactive DFGin BLBplus out-out out-out V04 ATP Type3 Type1
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA 3.2 Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB 3.2 Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 3Q53A 2.09 None DFGin BLAminus out-none in-in ATP Type1
Homo sapiens STE PAK4 PAK4_HUMAN Serine/threonine-protein kinase PAK 4 4XBRA 2.94 Inactive DFGin ABAminus in-in in-in ATP Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7HA 1.96 Inactive DFGin BLAminus in-out in-in ATP Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7HB 1.96 Inactive DFGin BLAminus out-out in-in ATP Type1
Homo sapiens STE STRADA STRAA_HUMAN STE20-related kinase adapter protein alpha 3GNIB 2.35 None DFGin BLAminus in-none in-out ATP Type1
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 9D5IA 1.5 Inactive DFGinter None out-out out-out ATP Type1
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 3KMWA 2.0 Inactive DFGinter None out-out out-out ATP Type1
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 3REPA 1.8 Inactive DFGinter None out-out out-out ATP Type1
Homo sapiens TKL KSR2 KSR2_HUMAN Kinase suppressor of Ras 2 2Y4IB 3.46 Inactive DFGin BLBplus out-none out-out ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9A 3.48 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9C 3.48 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 Inactive DFGinter None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9E 3.48 Inactive DFGout None out-out out-in ATP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8PO4B 1.621 Inactive DFGin BLBtrans out-out out-out ATP Type1
Homo sapiens TYR INSR INSR_HUMAN Insulin receptor 3BU5A 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5I4NA 1.54 Inactive DFGin None out-none out-out ATP Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4FVRA 2.0 Inactive DFGin None out-none out-out ATP Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4FVQA 1.75 Inactive DFGin None out-none out-out ATP Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8C08A 2.2 Inactive DFGin None in-none out-out ATP Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8C08B 2.2 Inactive DFGin None out-none out-out ATP Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 3DKCA 1.52 Inactive DFGin BLBplus out-out out-out ATP Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMA 2.187 Inactive DFGin None in-in none-out ATP Type1
Miscanthus lutarioriparius TKL RIPK A0A811MC32_9POAL non-specific serine/threonine protein kinase 8HOAA 1.676 Inactive DFGin BLBplus out-none none-out ATP HX2 Type1 Allosteric
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1ATPE 2.2 Inactive DFGin BLAminus in-out in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3FJQE 1.6 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH1A 2.0 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH3A 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DINA 3.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4X6RA 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2UA 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2VA 1.77 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2WA 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4XW5A 1.95 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3QAME 1.92 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3QALE 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1RDQE 1.26 Active DFGin BLAminus in-in in-in ADP ATP Type1 Type1
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YAAA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YAAB 2.3 Inactive DFGin BLAminus out-out in-in ATP Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB 2.6 Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus STE STK39 STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase 5D9HA 3.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
Mus musculus STE STK39 STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase 5D9HB 3.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
Mus musculus TKL RIPK4 RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 5WNIA 2.65 Inactive DFGin BLAminus in-in in-out ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2PHKA 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1QL6A 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1PHKA 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 2Y4IC 3.46 Inactive DFGin BLBplus out-out out-out ATP Type1
Oryza sativa OTHER FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUPA 1.98 Inactive DFGin BLAminus in-in in-out ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUA 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUB 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUC 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4GT3A 1.68 None DFGin BLAminus in-none in-in ATP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 1GOLA 2.8 None DFGin BLAminus out-none in-in ATP Type1
Rattus norvegicus STE TAOK2 TAOK2_RAT Serine/threonine-protein kinase TAO2 1U5RA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Rattus norvegicus STE TAOK2 TAOK2_RAT Serine/threonine-protein kinase TAO2 1U5RB 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Saccharomyces cerevisiae CMGC CKA1 CSK21_YEAST Casein kinase II subunit alpha 4FI1A 2.09 Inactive None None out-none in-in ATP Type1
Saccharomyces cerevisiae CMGC CKA1 CSK21_YEAST Casein kinase II subunit alpha 4MWHA 2.09 Inactive None None out-none in-in ATP Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q97A 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive DFGin BLBminus out-out out-out ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive DFGin BLBminus out-out none-out ATP Type1
Schizosaccharomyces pombe CK1 CKI1 CKI1_SCHPO Casein kinase I homolog 1 1CSNA 2.0 Active DFGin BLAminus in-in in-in ATP Type1

Protein kinases in complex with ATP

Total number of genes: 20
Total number of chains: 62
Spatial Dihedral Chains Representative
DFGin BLAminus 41 1RDQE
DFGin BLBminus 3 7Z9TBBB
DFGin BLBplus 2 8HOAA
DFGin BLBtrans 2 5D9HB
DFGin None 12 4CYIA
None None 2 4FI1A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPYA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDVA 1.97 None DFGin BLAminus in-none in-none ATP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDVB 1.97 None DFGin BLAminus in-none in-none ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3T8OA 2.5 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4WA 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4WB 2.7 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4XA 2.9 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4XB 2.9 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 9DW9G 2.8 Active DFGin BLAminus in-in in-in ATP Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q24A 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIA 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIB 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIC 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYID 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIE 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIF 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIG 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIH 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJA 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJB 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJC 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum OTHER PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJD 2.59 Inactive DFGin None out-none out-none ATP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EMAA 1.88 Active DFGin BLAminus in-in in-in ATP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Y8CA 1.76 Active DFGin BLAminus in-in in-in ATP Type1
Miscanthus lutarioriparius TKL RIPK A0A811MC32_9POAL non-specific serine/threonine protein kinase 8HOAA 1.676 Inactive DFGin BLBplus out-none none-out ATP HX2 Type1 Allosteric
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1ATPE 2.2 Inactive DFGin BLAminus in-out in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3FJQE 1.6 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH1A 2.0 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH3A 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DINA 3.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4X6RA 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2UA 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2VA 1.77 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3X2WA 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4XW5A 1.95 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3QAME 1.92 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 3QALE 1.7 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1RDQE 1.26 Active DFGin BLAminus in-in in-in ADP ATP Type1 Type1
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YAAA 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YAAB 2.3 Inactive DFGin BLAminus out-out in-in ATP Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB 2.6 Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus STE STK39 STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase 5D9HA 3.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
Mus musculus STE STK39 STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase 5D9HB 3.1 Inactive DFGin BLBtrans out-out out-out ATP Type1
Mus musculus TKL RIPK4 RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 5WNIA 2.65 Inactive DFGin BLAminus in-in in-out ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2PHKA 2.6 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1QL6A 2.4 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus CAMK PHKG1 PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1PHKA 2.2 Active DFGin BLAminus in-in in-in ATP Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 2Y4IC 3.46 Inactive DFGin BLBplus out-out out-out ATP Type1
Oryza sativa OTHER FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUPA 1.98 Inactive DFGin BLAminus in-in in-out ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUA 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUB 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Plasmodium falciparum CMGC CK1 Q8IIR9_PLAF7 non-specific serine/threonine protein kinase 5XVUC 3.0 Active DFGin BLAminus in-in in-in ATP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4GT3A 1.68 None DFGin BLAminus in-none in-in ATP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 1GOLA 2.8 None DFGin BLAminus out-none in-in ATP Type1
Rattus norvegicus STE TAOK2 TAOK2_RAT Serine/threonine-protein kinase TAO2 1U5RA 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Rattus norvegicus STE TAOK2 TAOK2_RAT Serine/threonine-protein kinase TAO2 1U5RB 2.1 Active DFGin BLAminus in-in in-in ATP Type1
Saccharomyces cerevisiae CMGC CKA1 CSK21_YEAST Casein kinase II subunit alpha 4FI1A 2.09 Inactive None None out-none in-in ATP Type1
Saccharomyces cerevisiae CMGC CKA1 CSK21_YEAST Casein kinase II subunit alpha 4MWHA 2.09 Inactive None None out-none in-in ATP Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q97A 2.3 Active DFGin BLAminus in-in in-in ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive DFGin BLBminus out-out out-out ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive DFGin BLBminus out-out none-out ATP Type1
Schizosaccharomyces pombe CK1 CKI1 CKI1_SCHPO Casein kinase I homolog 1 1CSNA 2.0 Active DFGin BLAminus in-in in-in ATP Type1