OTHER_WNK3 (Serine/threonine-protein kinase WNK3)

Total number of chains: 17
Active chains: 4
Uniprot: WNK3_HUMAN
Kinase Domain Residues: 146 - 405
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 10 58.8% AF-Q9BYP7-K1A
DFGin BLBminus 4 23.5% 5O1VA
DFGin None 2 11.8% 5O23A
DFGin BLBtrans 1 5.9% 5O2BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
5O26A 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
5O26B 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
AF-Q9BYP7-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3
AF-Q9BYP7-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3
5O21A 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 407 0 SEP304 None Serine/threonine-protein kinase WNK3
5O21B 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3
8EDHC 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 136 - 407 0 None S308A Serine/threonine-protein kinase WNK3
9D7QA 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 130 - 407 0 None E314A Serine/threonine-protein kinase WNK3
9D7QB 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 132 - 407 0 None E314A Serine/threonine-protein kinase WNK3
8EDHA 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn WGK Type1 137 - 406 0 None S308A Serine/threonine-protein kinase WNK3
5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3
5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3
5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3
5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3
5O2BA 2.038 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_nnoo KS1 Type1 132 - 414 0 None None Serine/threonine-protein kinase WNK3
5O23A 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 136 - 405 0 SEP304 None Serine/threonine-protein kinase WNK3
5O23B 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 132 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3

OTHER_WNK3 (Serine/threonine-protein kinase WNK3)

Total number of chains: 17
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 10 58.8% AF-Q9BYP7-K1A
DFGin BLBminus 4 23.5% 5O1VA
DFGin None 2 11.8% 5O23A
DFGin BLBtrans 1 5.9% 5O2BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN AF-Q9BYP7-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN AF-Q9BYP7-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O21A 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 407 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O21B 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 8EDHC 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 136 - 407 0 None S308A Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 9D7QA 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 130 - 407 0 None E314A Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 9D7QB 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 132 - 407 0 None E314A Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 8EDHA 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn WGK Type1 137 - 406 0 None S308A Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O2BA 2.038 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_nnoo KS1 Type1 132 - 414 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O23A 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 136 - 405 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
WNK3_HUMAN 5O23B 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 132 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens

OTHER_WNK3 (Serine/threonine-protein kinase WNK3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism