PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 698 - 1022 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 698 - 1022 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism