TYR_EPHB2 (Ephrin type-B receptor 2)

Total number of chains: 3
Active chains: 2
Uniprot: EPHB2_HUMAN
Kinase Domain Residues: 621 - 882
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-P29323-K1A
DFGin None 1 33.3% 3ZFMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P29323-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2
AF-P29323-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2
3ZFMA 2.27 Inactive DFGin‑None in-none none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 615 - 894 0 None None Ephrin type-B receptor 2

TYR_EPHB2 (Ephrin type-B receptor 2)

Total number of chains: 9
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 66.7% AF-P29323-K1A
DFGin None 3 33.3% 1JPAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
EPHB2_HUMAN AF-P29323-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2 Homo sapiens
EPHB2_HUMAN AF-P29323-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2 Homo sapiens
EPHB2_HUMAN 3ZFMA 2.27 Inactive DFGin‑None in-none none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 615 - 894 0 None None Ephrin type-B receptor 2 Homo sapiens
EPHB2_MOUSE 1JPAA 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 892 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 1JPAB 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 891 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus

TYR_EPHB2 (Ephrin type-B receptor 2)

Total number of chains: 6
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% 2HENA
DFGin None 2 33.3% 1JPAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
EPHB2_MOUSE 1JPAA 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 892 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 1JPAB 1.91 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 594 - 891 0 None Y596F,Y602F Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus