OTHER_CDC7 (Cell division cycle 7-related protein kinase)

Total number of chains: 11
Active chains: 2
Uniprot: CDC7_HUMAN
Kinase Domain Residues: 58 - 569
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 11 100.0% AF-O00311-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O00311-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase
AF-O00311-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase
4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase
4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase
4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase
6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase
6YA8A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase
4F9BA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase
4F9BC 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase
4F9CA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase
6YA6A 1.44 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase

OTHER_CDC7 (Cell division cycle 7-related protein kinase)

Total number of chains: 16
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 75.0% AF-O00311-K1A
DFGin ABAminus 3 18.8% 7PT68
DFGin BLAplus 1 6.2% 7P5Z1
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDC7_HUMAN AF-O00311-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN AF-O00311-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 6YA8A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F9BA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F9BC 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 4F9CA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_HUMAN 6YA6A 1.44 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae

OTHER_CDC7 (Cell division cycle 7-related protein kinase)

Total number of chains: 5
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 60.0% 7PT68
DFGin BLAminus 1 20.0% 7V3VH
DFGin BLAplus 1 20.0% 7P5Z1
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae