FGFR2 (Fibroblast growth factor receptor 2)

Group: TYR
Uniprot: FGFR2_HUMAN
Domain boundary: 481 - 759


Total number of chains: 98
Spatial Dihedral Chains Representative
DFGin BLAminus 87 AF-P21802-K1A
DFGin BLAplus 7 8W2XA
DFGin BLBminus 1 6V6QC
DFGin None 3 8STGB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8SWEA 2.24 Active DFGin BLAminus in-in in-in GSH WXQ Allosteric Type1 468 - 765 None None 0
4J96A 2.297 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 766 C491A,K659M None 0
4J98A 2.307 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 764 C491A,K659Q None 0
AF-P21802-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 473 - 767 None None 0
1GJOA 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 467 - 764 None None 0
5UI0A 2.05 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 766 C491A,E565A None 0
2PSQA 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 468 - 765 None None 0
2PSQB 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 467 - 766 None None 0
2PWLA 2.4 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,N549H None 0
2PWLB 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,N549H None 0
5UGLA 1.861 Active DFGin BLAminus in-in in-in ANP Type1 468 - 764 D650V None 0
5UGLB 1.861 Active DFGin BLAminus in-in in-in ANP Type1 467 - 764 D650V None 11
4J96B 2.297 Inactive DFGin BLAminus in-out in-in ACP Type1 462 - 766 C491A,K659M None 0
4J98B 2.307 Active DFGin BLAminus in-in in-in ACP Type1 461 - 764 C491A,K659Q None 0
2PVFA 1.8 Active DFGin BLAminus in-in in-in ACP Type1 467 - 765 C491A X586,X656,X657 0
3CLYA 2.0 Active DFGin BLAminus in-in in-in ACP Type1 468 - 772 C491A X656,X657 0
4J99A 1.847 Active DFGin BLAminus in-in in-in ACP Type1 466 - 764 C491A,K659T None 4
4J99B 1.847 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659T None 0
4J99C 1.847 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659T None 0
4J99D 1.847 Active DFGin BLAminus in-in in-in ACP Type1 465 - 764 C491A,K659T None 3
2PVYA 2.2 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 0
2PVYB 2.2 Active DFGin BLAminus in-in in-in ACP Type1 462 - 764 C491A,K659N None 6
2PVYC 2.2 Active DFGin BLAminus in-in in-in ACP Type1 462 - 764 C491A,K659N None 5
2PVYD 2.2 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 0
4J95A 2.377 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 4
4J95B 2.377 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659N None 0
4J95C 2.377 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659N None 0
4J95D 2.377 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 11
2PZ5A 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,N549T None 0
2PZ5B 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,N549T None 0
4J97A 2.548 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659E None 0
4J97B 2.548 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659E None 0
4J97C 2.548 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659E None 0
4J97D 2.548 Active DFGin BLAminus in-in in-in ACP Type1 466 - 764 C491A,K659E None 0
2PZPA 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,K526E None 0
2PZPB 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,K526E None 0
2PZRA 3.0 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,K641R None 0
2PZRB 3.0 Active DFGin BLAminus in-in in-in ACP Type1 467 - 766 C491A,K641R None 0
5UHNA 2.909 Active DFGin BLAminus in-in in-in ACP Type1 469 - 764 N549H,E565A None 0
5UHNB 2.909 Active DFGin BLAminus in-in in-in ACP Type1 469 - 764 N549H,E565A None 11
3B2TA 1.8 Inactive DFGin BLAminus in-out in-in M33 Type1 464 - 768 A628T,E767Q None 0
3B2TB 1.8 Active DFGin BLAminus in-in in-in M33 Type1 458 - 764 A628T,E767Q None 0
7OZYAAA 2.28 Active DFGin BLAminus in-in in-in 47I Type1 467 - 762 None None 0
7OZYBBB 2.28 Active DFGin BLAminus in-in in-in 47I Type1 467 - 762 None None 0
8H75A 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 765 None X656 0
8H75B 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 764 None X656 0
8H75C 3.75 Inactive DFGin BLAminus in-in out-in KX0 Type1 467 - 763 None X656 6
8H75D 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 764 None X656 4
6LVKA 2.29 Active DFGin BLAminus in-in in-in EVC Type1 468 - 766 None X561 0
6LVKB 2.29 Active DFGin BLAminus in-in in-in EVC Type1 468 - 765 None X561 0
6LVLA 2.98 Active DFGin BLAminus in-in in-in EVL Type1 468 - 766 None None 0
6LVLB 2.98 Active DFGin BLAminus in-in in-in EVL Type1 468 - 765 None None 0
3RI1B 2.1 Active DFGin BLAminus in-in in-in 3RH Type1 468 - 766 None None 0
1OECA 2.4 Active DFGin BLAminus in-in in-in AA2 Type1 467 - 765 None None 0
8SWEB 2.24 Inactive DFGin BLAminus in-out in-in WXQ Type1 468 - 767 None None 0
5UGXA 2.349 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,E565A None 0
5UGXB 2.349 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,E565A None 10
5UI0B 2.05 Active DFGin BLAminus in-in in-in ACP Type1 462 - 765 C491A,E565A None 0
7KIAA 2.22 Active DFGin BLAminus in-in in-in WFD Type1 467 - 764 V564F None 0
7KIAB 2.22 Active DFGin BLAminus in-in in-in WFD Type1 467 - 767 V564F None 0
7KIEA 2.47 Active DFGin BLAminus in-in in-in WF7 Type1 466 - 766 V564F None 0
7KIEB 2.47 Active DFGin BLAminus in-in in-in WF7 Type1 466 - 767 V564F None 0
2Q0BA 2.9 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,E565A None 0
2Q0BB 2.9 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565A None 0
2PY3A 2.3 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565G None 0
2PY3B 2.3 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565G None 0
5EG3A 2.606 Active DFGin BLAminus in-in in-in ACP Type1 466 - 774 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E X769 0
6V6QA 2.46 Active DFGin BLAminus in-in in-in ACP Type1 466 - 765 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 0
6V6QB 2.46 Active DFGin BLAminus in-in in-in ACP Type1 467 - 766 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 0
6V6QD 2.46 Active DFGin BLAminus in-in in-in ACP Type1 467 - 765 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 9
8W3BA 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 5
8W3BB 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 11
8W3BC 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 4
8W3BD 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 465 - 764 D650V None 11
8W3DA 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549K,D650V None 0
8W3DB 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 463 - 764 N549K,D650V None 7
8W3DC 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 766 N549K,D650V None 0
8W3DD 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 463 - 765 N549K,D650V None 2
6AGXA 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 5
6AGXB 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 0
6AGXC 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 5
6AGXD 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 0
3RI1A 2.1 Active DFGin BLAminus in-in in-in 3RH Type1.5_Back 468 - 765 None None 0
8W38A 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 0
8W38B 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 6
8W38C 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 465 - 764 N549D,D650V None 11
8W38D 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 11
8E1XA 2.68 Inactive DFGin BLAplus in-in out-out U9P Type1 468 - 762 None X561,X586 5
8E1XB 2.68 Inactive DFGin BLAplus in-in out-out U9P Type1 467 - 765 None X561,X586 2
8STGA 3.79 Inactive DFGin BLAplus in-out none-in WCJ Type1 461 - 764 None None 17
9U3NA 3.25 Inactive DFGin BLAplus in-out none-in A1ENT Type1 461 - 764 V564F None 15
8W2XA 2.98 Inactive DFGin BLAplus in-in out-out A1AFR Type1.5_Back 458 - 765 None None 0
8W2XB 2.98 Inactive DFGin BLAplus in-in out-out A1AFR Type1.5_Back 458 - 765 None None 3
8U1FA 3.33 Inactive DFGin BLAplus in-out none-in UIM Type1.5_Back 460 - 764 None None 17
6V6QC 2.46 Inactive DFGin BLBminus in-in in-in ACP Type1 467 - 766 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 11
8U1FB 3.33 Inactive DFGin None in-out none-out UIM Type1.5_Back 472 - 765 None None 16
8STGB 3.79 Inactive DFGin None in-out none-in WCJ Type1.5_Back 472 - 765 None None 10
9U3NB 3.25 Inactive DFGin None in-in none-out A1ENT Type1.5_Back 470 - 764 V564F None 13

FGFR2 (Fibroblast growth factor receptor 2)

Group: TYR
Total number of chains: 98
Spatial Dihedral Chains Representative
DFGin BLAminus 87 AF-P21802-K1A
DFGin BLAplus 7 8W2XA
DFGin BLBminus 1 6V6QC
DFGin None 3 8STGB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens FGFR2_HUMAN 8SWEA 2.24 Active DFGin BLAminus in-in in-in GSH WXQ Allosteric Type1 468 - 765 None None 0
Homo sapiens FGFR2_HUMAN 4J96A 2.297 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 766 C491A,K659M None 0
Homo sapiens FGFR2_HUMAN 4J98A 2.307 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 764 C491A,K659Q None 0
Homo sapiens FGFR2_HUMAN AF-P21802-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 473 - 767 None None 0
Homo sapiens FGFR2_HUMAN 1GJOA 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 467 - 764 None None 0
Homo sapiens FGFR2_HUMAN 5UI0A 2.05 Active DFGin BLAminus in-in in-in No_ligand No_ligand 461 - 766 C491A,E565A None 0
Homo sapiens FGFR2_HUMAN 2PSQA 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 468 - 765 None None 0
Homo sapiens FGFR2_HUMAN 2PSQB 2.4 Active DFGin BLAminus in-in in-in No_ligand No_ligand 467 - 766 None None 0
Homo sapiens FGFR2_HUMAN 2PWLA 2.4 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,N549H None 0
Homo sapiens FGFR2_HUMAN 2PWLB 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,N549H None 0
Homo sapiens FGFR2_HUMAN 5UGLA 1.861 Active DFGin BLAminus in-in in-in ANP Type1 468 - 764 D650V None 0
Homo sapiens FGFR2_HUMAN 5UGLB 1.861 Active DFGin BLAminus in-in in-in ANP Type1 467 - 764 D650V None 11
Homo sapiens FGFR2_HUMAN 4J96B 2.297 Inactive DFGin BLAminus in-out in-in ACP Type1 462 - 766 C491A,K659M None 0
Homo sapiens FGFR2_HUMAN 4J98B 2.307 Active DFGin BLAminus in-in in-in ACP Type1 461 - 764 C491A,K659Q None 0
Homo sapiens FGFR2_HUMAN 2PVFA 1.8 Active DFGin BLAminus in-in in-in ACP Type1 467 - 765 C491A X586,X656,X657 0
Homo sapiens FGFR2_HUMAN 3CLYA 2.0 Active DFGin BLAminus in-in in-in ACP Type1 468 - 772 C491A X656,X657 0
Homo sapiens FGFR2_HUMAN 4J99A 1.847 Active DFGin BLAminus in-in in-in ACP Type1 466 - 764 C491A,K659T None 4
Homo sapiens FGFR2_HUMAN 4J99B 1.847 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659T None 0
Homo sapiens FGFR2_HUMAN 4J99C 1.847 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659T None 0
Homo sapiens FGFR2_HUMAN 4J99D 1.847 Active DFGin BLAminus in-in in-in ACP Type1 465 - 764 C491A,K659T None 3
Homo sapiens FGFR2_HUMAN 2PVYA 2.2 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 0
Homo sapiens FGFR2_HUMAN 2PVYB 2.2 Active DFGin BLAminus in-in in-in ACP Type1 462 - 764 C491A,K659N None 6
Homo sapiens FGFR2_HUMAN 2PVYC 2.2 Active DFGin BLAminus in-in in-in ACP Type1 462 - 764 C491A,K659N None 5
Homo sapiens FGFR2_HUMAN 2PVYD 2.2 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 0
Homo sapiens FGFR2_HUMAN 4J95A 2.377 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 4
Homo sapiens FGFR2_HUMAN 4J95B 2.377 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659N None 0
Homo sapiens FGFR2_HUMAN 4J95C 2.377 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659N None 0
Homo sapiens FGFR2_HUMAN 4J95D 2.377 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659N None 11
Homo sapiens FGFR2_HUMAN 2PZ5A 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,N549T None 0
Homo sapiens FGFR2_HUMAN 2PZ5B 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,N549T None 0
Homo sapiens FGFR2_HUMAN 4J97A 2.548 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659E None 0
Homo sapiens FGFR2_HUMAN 4J97B 2.548 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,K659E None 0
Homo sapiens FGFR2_HUMAN 4J97C 2.548 Active DFGin BLAminus in-in in-in ACP Type1 467 - 764 C491A,K659E None 0
Homo sapiens FGFR2_HUMAN 4J97D 2.548 Active DFGin BLAminus in-in in-in ACP Type1 466 - 764 C491A,K659E None 0
Homo sapiens FGFR2_HUMAN 2PZPA 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,K526E None 0
Homo sapiens FGFR2_HUMAN 2PZPB 2.4 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,K526E None 0
Homo sapiens FGFR2_HUMAN 2PZRA 3.0 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,K641R None 0
Homo sapiens FGFR2_HUMAN 2PZRB 3.0 Active DFGin BLAminus in-in in-in ACP Type1 467 - 766 C491A,K641R None 0
Homo sapiens FGFR2_HUMAN 5UHNA 2.909 Active DFGin BLAminus in-in in-in ACP Type1 469 - 764 N549H,E565A None 0
Homo sapiens FGFR2_HUMAN 5UHNB 2.909 Active DFGin BLAminus in-in in-in ACP Type1 469 - 764 N549H,E565A None 11
Homo sapiens FGFR2_HUMAN 3B2TA 1.8 Inactive DFGin BLAminus in-out in-in M33 Type1 464 - 768 A628T,E767Q None 0
Homo sapiens FGFR2_HUMAN 3B2TB 1.8 Active DFGin BLAminus in-in in-in M33 Type1 458 - 764 A628T,E767Q None 0
Homo sapiens FGFR2_HUMAN 7OZYAAA 2.28 Active DFGin BLAminus in-in in-in 47I Type1 467 - 762 None None 0
Homo sapiens FGFR2_HUMAN 7OZYBBB 2.28 Active DFGin BLAminus in-in in-in 47I Type1 467 - 762 None None 0
Homo sapiens FGFR2_HUMAN 8H75A 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 765 None X656 0
Homo sapiens FGFR2_HUMAN 8H75B 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 764 None X656 0
Homo sapiens FGFR2_HUMAN 8H75C 3.75 Inactive DFGin BLAminus in-in out-in KX0 Type1 467 - 763 None X656 6
Homo sapiens FGFR2_HUMAN 8H75D 3.75 Inactive DFGin BLAminus in-out in-in KX0 Type1 467 - 764 None X656 4
Homo sapiens FGFR2_HUMAN 6LVKA 2.29 Active DFGin BLAminus in-in in-in EVC Type1 468 - 766 None X561 0
Homo sapiens FGFR2_HUMAN 6LVKB 2.29 Active DFGin BLAminus in-in in-in EVC Type1 468 - 765 None X561 0
Homo sapiens FGFR2_HUMAN 6LVLA 2.98 Active DFGin BLAminus in-in in-in EVL Type1 468 - 766 None None 0
Homo sapiens FGFR2_HUMAN 6LVLB 2.98 Active DFGin BLAminus in-in in-in EVL Type1 468 - 765 None None 0
Homo sapiens FGFR2_HUMAN 3RI1B 2.1 Active DFGin BLAminus in-in in-in 3RH Type1 468 - 766 None None 0
Homo sapiens FGFR2_HUMAN 1OECA 2.4 Active DFGin BLAminus in-in in-in AA2 Type1 467 - 765 None None 0
Homo sapiens FGFR2_HUMAN 8SWEB 2.24 Inactive DFGin BLAminus in-out in-in WXQ Type1 468 - 767 None None 0
Homo sapiens FGFR2_HUMAN 5UGXA 2.349 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,E565A None 0
Homo sapiens FGFR2_HUMAN 5UGXB 2.349 Active DFGin BLAminus in-in in-in ACP Type1 468 - 764 C491A,E565A None 10
Homo sapiens FGFR2_HUMAN 5UI0B 2.05 Active DFGin BLAminus in-in in-in ACP Type1 462 - 765 C491A,E565A None 0
Homo sapiens FGFR2_HUMAN 7KIAA 2.22 Active DFGin BLAminus in-in in-in WFD Type1 467 - 764 V564F None 0
Homo sapiens FGFR2_HUMAN 7KIAB 2.22 Active DFGin BLAminus in-in in-in WFD Type1 467 - 767 V564F None 0
Homo sapiens FGFR2_HUMAN 7KIEA 2.47 Active DFGin BLAminus in-in in-in WF7 Type1 466 - 766 V564F None 0
Homo sapiens FGFR2_HUMAN 7KIEB 2.47 Active DFGin BLAminus in-in in-in WF7 Type1 466 - 767 V564F None 0
Homo sapiens FGFR2_HUMAN 2Q0BA 2.9 Active DFGin BLAminus in-in in-in ACP Type1 468 - 765 C491A,E565A None 0
Homo sapiens FGFR2_HUMAN 2Q0BB 2.9 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565A None 0
Homo sapiens FGFR2_HUMAN 2PY3A 2.3 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565G None 0
Homo sapiens FGFR2_HUMAN 2PY3B 2.3 Active DFGin BLAminus in-in in-in ACP Type1 468 - 766 C491A,E565G None 0
Homo sapiens FGFR2_HUMAN 5EG3A 2.606 Active DFGin BLAminus in-in in-in ACP Type1 466 - 774 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E X769 0
Homo sapiens FGFR2_HUMAN 6V6QA 2.46 Active DFGin BLAminus in-in in-in ACP Type1 466 - 765 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 0
Homo sapiens FGFR2_HUMAN 6V6QB 2.46 Active DFGin BLAminus in-in in-in ACP Type1 467 - 766 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 0
Homo sapiens FGFR2_HUMAN 6V6QD 2.46 Active DFGin BLAminus in-in in-in ACP Type1 467 - 765 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 9
Homo sapiens FGFR2_HUMAN 8W3BA 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 5
Homo sapiens FGFR2_HUMAN 8W3BB 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 11
Homo sapiens FGFR2_HUMAN 8W3BC 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 D650V None 4
Homo sapiens FGFR2_HUMAN 8W3BD 2.23 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 465 - 764 D650V None 11
Homo sapiens FGFR2_HUMAN 8W3DA 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549K,D650V None 0
Homo sapiens FGFR2_HUMAN 8W3DB 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 463 - 764 N549K,D650V None 7
Homo sapiens FGFR2_HUMAN 8W3DC 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 766 N549K,D650V None 0
Homo sapiens FGFR2_HUMAN 8W3DD 2.04 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 463 - 765 N549K,D650V None 2
Homo sapiens FGFR2_HUMAN 6AGXA 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 5
Homo sapiens FGFR2_HUMAN 6AGXB 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 0
Homo sapiens FGFR2_HUMAN 6AGXC 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 5
Homo sapiens FGFR2_HUMAN 6AGXD 2.95 Inactive DFGin BLAminus in-out in-in 9WX Type1.5_Back 467 - 764 A628T X586,X588,X656,X657 0
Homo sapiens FGFR2_HUMAN 3RI1A 2.1 Active DFGin BLAminus in-in in-in 3RH Type1.5_Back 468 - 765 None None 0
Homo sapiens FGFR2_HUMAN 8W38A 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 0
Homo sapiens FGFR2_HUMAN 8W38B 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 6
Homo sapiens FGFR2_HUMAN 8W38C 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 465 - 764 N549D,D650V None 11
Homo sapiens FGFR2_HUMAN 8W38D 2.6 Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 N549D,D650V None 11
Homo sapiens FGFR2_HUMAN 8E1XA 2.68 Inactive DFGin BLAplus in-in out-out U9P Type1 468 - 762 None X561,X586 5
Homo sapiens FGFR2_HUMAN 8E1XB 2.68 Inactive DFGin BLAplus in-in out-out U9P Type1 467 - 765 None X561,X586 2
Homo sapiens FGFR2_HUMAN 8STGA 3.79 Inactive DFGin BLAplus in-out none-in WCJ Type1 461 - 764 None None 17
Homo sapiens FGFR2_HUMAN 9U3NA 3.25 Inactive DFGin BLAplus in-out none-in A1ENT Type1 461 - 764 V564F None 15
Homo sapiens FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin BLAplus in-in out-out A1AFR Type1.5_Back 458 - 765 None None 0
Homo sapiens FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin BLAplus in-in out-out A1AFR Type1.5_Back 458 - 765 None None 3
Homo sapiens FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin BLAplus in-out none-in UIM Type1.5_Back 460 - 764 None None 17
Homo sapiens FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin BLBminus in-in in-in ACP Type1 467 - 766 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F X656 11
Homo sapiens FGFR2_HUMAN 8U1FB 3.33 Inactive DFGin None in-out none-out UIM Type1.5_Back 472 - 765 None None 16
Homo sapiens FGFR2_HUMAN 8STGB 3.79 Inactive DFGin None in-out none-in WCJ Type1.5_Back 472 - 765 None None 10
Homo sapiens FGFR2_HUMAN 9U3NB 3.25 Inactive DFGin None in-in none-out A1ENT Type1.5_Back 470 - 764 V564F None 13

FGFR2 (Fibroblast growth factor receptor 2)

No non-human structures known.