4IZ5

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 3.19

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-out ADP Type1 11 - 357 0
B Inactive DFGin BLAminus in-out in-out ADP Type1 11 - 357 0
C Inactive DFGin BLAminus in-out in-out ADP Type1 11 - 357 0
D Inactive DFGin BLAminus in-out in-out ADP Type1 11 - 357 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        14         24         34         44 
gpggagPEMV RGQVFDVGPR YTNLSYIGEG AYGMVCSAYD 
        54         64         74         84 
NVNKVRVAIK KISPFEHQTY CQRTLREIKI LLRFRHENII 
        94        104        114        124 
GINDIIRAPT IEQMKDVYIV QDLMETDLYK LLKTQHLSND 
       134        144        154        164 
HICYFLYQIL RGLKYIHSAN VLHRDLKPSN LLLNTTCDLK 
       174        184        194        204 
ICDFGLARVA DPDHDHTGFL EEYVATRWYR APEIMLNSKG 
       214        224        234        244 
YTKSIDIWSV GCILAEMLSN RPIFPGKHYL DQLNHILGIL 
       254        264        274        284 
GSPSQEDLNC IINLKARNYL LSLPHKNKVP WNRLFPNADS 
       294        304        314        324 
KALDLLDKML TFNPHKRIEV EQALAHPYLE QYYDPSDEPI 
       334        344        354 
AEAPFKFDME LDDLPKEKLK ELIFEETARF QPGyrs
Lower-case residues are disordered in structure.
Mutations: T185E
Phosphorylation: None