CASK (Peripheral plasma membrane protein CASK)

Pseudokinase
Group: CAMK
Uniprot: CSKP_HUMAN
Domain boundary: 12 - 276


Total number of chains: 28
Spatial Dihedral Chains Representative
DFGin BLAminus 28 3C0IA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
3MFTA 2.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 5 - 306 P22A,H145E,C146N,G162D None 0
6KMHA 2.4 Active DFGin BLAminus out-in in-in No_ligand No_ligand 5 - 318 None None 0
6KMHB 2.4 Active DFGin BLAminus out-in in-in No_ligand No_ligand 5 - 319 None None 0
3TACA 2.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1 - 316 None None 0
3MFRA 2.0 Active DFGin BLAminus in-in in-in ANP Type1 5 - 306 P22A,H145E,C146N,G162D None 0
3MFSA 2.1 Active DFGin BLAminus in-in in-in ANP Type1 4 - 306 P22A,H145E,C146N,G162D None 0
3MFUA 2.3 Active DFGin BLAminus in-in in-in ANP Type1 5 - 306 P22A,H145E,C146N,G162D None 0
3C0GA 2.19 Active DFGin BLAminus in-in in-in 3AM Type1 6 - 322 None None 0
3C0GB 2.19 Active DFGin BLAminus in-in in-in 3AM Type1 5 - 324 None None 0
3C0HA 2.3 Active DFGin BLAminus in-in in-in AMP Type1 5 - 304 None None 0
3C0HB 2.3 Active DFGin BLAminus in-in in-in AMP Type1 5 - 304 None None 0
3C0IA 1.85 Active DFGin BLAminus in-in in-in 3AM Type1 6 - 303 None None 0
7OAIA 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
7OAIB 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
7OAIC 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
7OAID 2.3 Active DFGin BLAminus in-in in-in V5W Type1 6 - 303 None None 0
7OAJA 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 303 None None 0
7OAJB 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
7OAJC 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
7OAJD 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
7OAKA 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
7OAKB 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
7OAKC 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
7OAKD 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
7OALA 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
7OALB 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
7OALC 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
7OALD 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0

CASK (Peripheral plasma membrane protein CASK)

Pseudokinase
Group: CAMK
Total number of chains: 31
Spatial Dihedral Chains Representative
DFGin BLAminus 31 3C0IA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens CSKP_HUMAN 3MFTA 2.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 5 - 306 P22A,H145E,C146N,G162D None 0
Homo sapiens CSKP_HUMAN 6KMHA 2.4 Active DFGin BLAminus out-in in-in No_ligand No_ligand 5 - 318 None None 0
Homo sapiens CSKP_HUMAN 6KMHB 2.4 Active DFGin BLAminus out-in in-in No_ligand No_ligand 5 - 319 None None 0
Homo sapiens CSKP_HUMAN 3TACA 2.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1 - 316 None None 0
Homo sapiens CSKP_HUMAN 3MFRA 2.0 Active DFGin BLAminus in-in in-in ANP Type1 5 - 306 P22A,H145E,C146N,G162D None 0
Homo sapiens CSKP_HUMAN 3MFSA 2.1 Active DFGin BLAminus in-in in-in ANP Type1 4 - 306 P22A,H145E,C146N,G162D None 0
Homo sapiens CSKP_HUMAN 3MFUA 2.3 Active DFGin BLAminus in-in in-in ANP Type1 5 - 306 P22A,H145E,C146N,G162D None 0
Homo sapiens CSKP_HUMAN 3C0GA 2.19 Active DFGin BLAminus in-in in-in 3AM Type1 6 - 322 None None 0
Homo sapiens CSKP_HUMAN 3C0GB 2.19 Active DFGin BLAminus in-in in-in 3AM Type1 5 - 324 None None 0
Homo sapiens CSKP_HUMAN 3C0HA 2.3 Active DFGin BLAminus in-in in-in AMP Type1 5 - 304 None None 0
Homo sapiens CSKP_HUMAN 3C0HB 2.3 Active DFGin BLAminus in-in in-in AMP Type1 5 - 304 None None 0
Homo sapiens CSKP_HUMAN 3C0IA 1.85 Active DFGin BLAminus in-in in-in 3AM Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAIA 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAIB 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAIC 2.3 Active DFGin BLAminus in-in in-in V5W Type1 5 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAID 2.3 Active DFGin BLAminus in-in in-in V5W Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAJA 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAJB 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
Homo sapiens CSKP_HUMAN 7OAJC 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
Homo sapiens CSKP_HUMAN 7OAJD 1.93 Active DFGin BLAminus in-in in-in V6E Type1 6 - 302 None None 0
Homo sapiens CSKP_HUMAN 7OAKA 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAKB 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAKC 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OAKD 2.23 Active DFGin BLAminus in-in in-in V6B Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OALA 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OALB 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OALC 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
Homo sapiens CSKP_HUMAN 7OALD 2.17 Active DFGin BLAminus in-in in-in V62 Type1 6 - 303 None None 0
Rattus norvegicus CSKP_RAT 6LNMA 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0
Rattus norvegicus CSKP_RAT 6LNMC 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0
Rattus norvegicus CSKP_RAT 6LNME 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0

CASK (Peripheral plasma membrane protein CASK)

Pseudokinase
Group: CAMK
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 6LNMA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Rattus norvegicus CSKP_RAT 6LNMA 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0
Rattus norvegicus CSKP_RAT 6LNMC 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0
Rattus norvegicus CSKP_RAT 6LNME 2.4 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 6 - 335 None None 0