CK1_TTBK2 (Tau-tubulin kinase 2)

Total number of chains: 12
Active chains: 6
Family: CK1
Uniprot: TTBK2_HUMAN
Kinase Domain Residues: 21 - 282
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 50.0% 7Q8ZA
DFGin BLAminus 6 50.0% AF-Q6IQ55-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
AF-Q6IQ55-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 290 0 None None Tau-tubulin kinase 2
AF-Q6IQ55-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 290 0 None None Tau-tubulin kinase 2
6U0KA 1.744 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DTQ Type1 8 - 298 0 None None Tau-tubulin kinase 2
6U0KB 1.744 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DTQ Type1 8 - 299 0 None None Tau-tubulin kinase 2
7Q8YA 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 6 - 299 0 None None Tau-tubulin kinase 2
7Q8YB 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 7 - 299 0 None None Tau-tubulin kinase 2
7Q8ZA 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 6 - 299 0 None None Tau-tubulin kinase 2
7Q8ZB 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 7 - 299 0 None None Tau-tubulin kinase 2
7Q90A 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 6 - 299 0 None None Tau-tubulin kinase 2
7Q90B 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 7 - 299 0 None None Tau-tubulin kinase 2

CK1_TTBK2 (Tau-tubulin kinase 2)

Total number of chains: 12
Active chains: 6
Family: CK1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 50.0% 7Q8ZA
DFGin BLAminus 6 50.0% AF-Q6IQ55-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TTBK2_HUMAN 6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN AF-Q6IQ55-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 290 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN AF-Q6IQ55-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 290 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 6U0KA 1.744 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DTQ Type1 8 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 6U0KB 1.744 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DTQ Type1 8 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q8YA 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q8YB 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q8ZA 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q8ZB 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q90A 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
TTBK2_HUMAN 7Q90B 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens

CK1_TTBK2 (Tau-tubulin kinase 2)

Total number of chains: 0
Active chains: 0
Family: CK1
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism