All / BLBplus / All

Total number of chains: 913
Active chains: 0
Total number of genes: 61
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 913 100.0% 6DI1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7RA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 53 - 340 0 None None Ribosomal protein S6 kinase alpha-1
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
CAMK MKNK2 MKNK2_HUMAN 2HW7A 2.71 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno STU Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CJ5A 2.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4G Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CJEA 3.36 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4A Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CJHA 3.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno ET8 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CJWA 3.38 Inactive DFGin‑BLBplus out-in none-out nonTYR APEdihe_aaoii APEdist_nnno FYV Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CJYA 3.05 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4J Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CK3A 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F67 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CK6A 3.32 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno N45 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 6CKIA 2.95 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno FZJ Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CAMK MKNK2 MKNK2_HUMAN 9HRCA 3.161 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo A1IWO Type1 72 - 375 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2
CMGC CDK1 CDK1_HUMAN 4YC6A 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 4YC6C 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 4YC6E 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 4YC6G 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 6GU7C 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 6GU7E 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 6GU7G 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1
CMGC CDK1 CDK1_HUMAN 6GU7A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno FB8 Type1 1 - 293 0 None None Cyclin-dependent kinase 1
CMGC CDK2 CDK2_HUMAN 4FKUA 1.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 60K, 60K Allosteric, Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1AQ1A 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nooo STU Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1DI8A 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DTQ Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1FVTA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 106 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GIHA 2.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 1PU Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1JVPP 1.53 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 89E Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1KE5A 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo LS1 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1KE6A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno LS2 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1KE7A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo LS3 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1KE8A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo LS4 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1KE9A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo LS5 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1R78A 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno FMD Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2XNBA 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo Y8L Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BGHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3I6 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5IEVA 2.03 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo R0N Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4FKWA 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 62K Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7NVQA 2.05 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo STU Type1 1 - 294 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q4HA 1.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo HGH Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GIIA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1PU Type1 1 - 298 0 None F82H,L83V,K89T Cyclin-dependent kinase 2
CMGC CDK4 CDK4_HUMAN 6P8GB 2.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 18 - 299 0 None G43E,G47E Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 6P8HB 3.19 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 18 - 298 0 None None Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 2W99B 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 2 - 295 0 None G43E,G47E,T172A Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 2W9ZB 2.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 2 - 295 0 None G43E,G47E,T172A Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 2W96B 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 4 - 295 0 None G43E,G47E,T172D Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 9CSKB 2.253 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo A1AZ4 Type1 4 - 295 0 None G43E,G47E Cyclin-dependent kinase 4
CMGC CDK4 CDK4_HUMAN 9CSKD 2.253 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo A1AZ4 Type1 4 - 295 0 None G43E,G47E Cyclin-dependent kinase 4
CMGC CDK6 CDK6_HUMAN 1BLXA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 309 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 6OQLA 2.707 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1A Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 6OQOA 1.977 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1J Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 8I0MA 2.777 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno NJ6 Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 3NUPA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3NU Type1 12 - 300 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 3NUXA 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3NV Type1 10 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 4AUAA 2.31 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4AU Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 4EZ5A 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0RS Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 5L2IA 2.75 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LQQ Type1 10 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 5L2SA 2.27 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZV Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 5L2TA 2.37 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZZ Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 9D8UA 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno A1AZ4 Type1 11 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 9PE7A 2.05 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo A1CIF Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 9PE8A 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_nooo A1AZ4 Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6
CMGC CDK7 CDK7_HUMAN 8P4ZB 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno WZ8 Type1 10 - 310 0 None None Cyclin-dependent kinase 7
CMGC CDK8 CDK8_HUMAN 5HBHA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 5Y7 Type1 1 - 361 0 None None Cyclin-dependent kinase 8
CMGC MAPK10 MK10_HUMAN 4H36A 3.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4H3BA 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4H3BC 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK12 MK12_HUMAN 6UNAA 2.554 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 10 - 351 0 None Q31R Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 6UNAB 2.554 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 351 0 None Q31R Mitogen-activated protein kinase 12
CMGC MAPK13 MK13_HUMAN 8X23A 1.5 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 1 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK13 MK13_HUMAN 4YNOA 1.7 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 2 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK13 MK13_HUMAN 3COIA 2.09 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooo APEdist_nnoo No_ligand No_ligand 2 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK13 MK13_HUMAN 4EYMA 2.353 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 0RX Type1 2 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK13 MK13_HUMAN 5EKOA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo N17 Type1 2 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK14 MK14_HUMAN 3NEWA 2.51 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 3NE Allosteric 5 - 352 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OK Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MH2A 2.3 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 5 - 352 0 None F169Y Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5ETIA 2.8 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FI4A 2.2 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FI4 Type1 4 - 352 0 None R57K Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FKOA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FKO Type1 5 - 352 0 None R57K Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLNC 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 3FN Type1 3 - 352 0 None R57K Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6OHDA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno MKP Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1OVEA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 358 Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GC7A 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo B45 Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3S3IA 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo CQ0 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1ZZLA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo TZY Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2YIXA 2.3 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo YIX Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HRBA 2.2 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo I39 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1ZYJA 2.0 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BI5 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1ZZ2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno B11 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ZAZA 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK1 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3D7ZA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK5 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3IPHA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo G11 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3KF7A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nnoo L9G Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3RINA 2.2 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo I2O Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5MTXA 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn FJI Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5MTYA 2.31 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn HB9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5TBEA 2.44 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 78L Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 9Y8BA 1.97 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioo APEdist_nnno A1CTD Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5TCOA 2.1 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 79Q Type1 6 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 9Q5BA 2.05 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno A1CRZ Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6M9LA 2.45 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn J9G Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3DS6A 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3DS6B 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3DS6C 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3DS6D 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GFEA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P37 Type1 1 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3ITZA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P66 Type1 1 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LHJA 3.31 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LHJ Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3U8WA 2.15 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 09J Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2BALA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno PQA Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4AA4A 2.3 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo QC0 Type1 5 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4AA5A 2.38 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo NQB Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4AACA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo AAV Type1 5 - 359 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2QD9A 1.7 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn LGF Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MVLA 2.8 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 38P Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MVLB 2.8 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 38P Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MVMA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 39P Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MVMB 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanoo APEdist_nnnn 39P Type1 5 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NWWA 2.09 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 3NW Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3S4QA 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno NK0 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINA 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioo APEdist_nooo 1M8 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINB 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo 1M8 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KINC 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1M8 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIND 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1M8 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIPA 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1R9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIPB 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 1R9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIQA 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaini APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIQB 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaino APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIQC 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaini APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4KIQD 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaino APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FKLA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FKL Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FKNA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FKN Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FL4A 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FL4 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLSA 2.3 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLWA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FLW Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLYA 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLY Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLZA 2.23 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLZ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FMHA 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 533 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FMKA 1.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FMK Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FMMA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo XI2 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FMNA 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 530 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3E92A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo G6A Type1 3 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MPTA 1.89 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 1GK Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3DT1A 2.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P40 Type1 1 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4F9YA 1.85 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo LM3 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HL7A 1.88 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nnno I47, I46 Type1, Allosteric 6 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3ROCA 1.7 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaoni APEdist_nnoo 29A, 29B Type1, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HLLA 1.95 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaoni APEdist_nnoo I45, I46, PO2 Type1, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2I0HA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 222, 222 Type1, Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2RG5A 2.4 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 279 Type1.5_Back 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3BX5A 2.4 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 304 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3L8XA 2.4 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno N4D Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2RG6A 1.72 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno 287, 287 Type1.5_Back, Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9N88A 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9N88E 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W39A 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W39B 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3AA 2.606 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3AB 2.606 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER TBK1 TBK1_HUMAN 6NT9A 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6NT9B 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 5W5VA 3.645 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANW Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6BODA 3.197 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn E0P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6RSTA 3.29 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHQ Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IWOA 2.61 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1H4 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM2A 2.5 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM3A 3.342 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1
STE MAP2K1 MP2K1_HUMAN 3EQDA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQIA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5YT3C 2.9 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6U2GA 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6V2WB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEA 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type1 63 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNED 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type1 66 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8DGSB 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo AGS, LCJ ATPlike, Type1 38 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4AN3A 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_onno ATP, 5Y0 ATPlike, Type3 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4AN9A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_onoo ACP, 2P7 ATPlike, Type3 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3SLSA 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nooo ANP, 77D ATPlike, Type3 45 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3SLSB 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nooo ANP, 77D ATPlike, Type3 45 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B3MA 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ANP, SU5 ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B3MB 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ANP, SU5 ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B7RA 1.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ANP, T1K ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B7RB 1.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, T1K ATPlike, Type3 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B94A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ANP, T3W ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B94B 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, T3W ATPlike, Type3 41 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B9LA 1.7 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP, T4N ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7B9LB 1.7 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP, T4N ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ORNA 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3OR ATPlike, Type3 62 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3OS3A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, 3OS ATPlike, Type3 62 - 378 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3WIGA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, CHU ATPlike, Type3 62 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3DV3A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ATP, MEK ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3MBLA 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, LSG ATPlike, Type3 62 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3PP1A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, IZG ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQBA 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo ATP, LUG ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4U80A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo ANP, 3EX ATPlike, Type3 62 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 1S9JA 2.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo ATP, BBM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3DY7A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ATP, 1CX ATPlike, Type3 62 - 364 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3E8NA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_onoo ATP, VRA ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3VVHA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn ATP, 4BM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3VVHB 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ATP, 4BM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3VVHC 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, 4BM ATPlike, Type3 62 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4ARKA 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, M3K ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4LMNA 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEE 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type3 62 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQGA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP, 4BM ATPlike, Type3 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7UMBC 3.231 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, U9F ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6PP9B 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, LCJ ATPlike, Type3 38 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0VB 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0WB 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOA ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0XB 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0YB 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 43 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0ZB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, CHU ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8DGTB 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo AGS, LCJ ATPlike, Type3 43 - 385 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 6NYBB 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, LCJ ATPlike, Type3 56 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9MMPB 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9MMQB 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9MMRB 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9MMSB 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 63 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEH 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ACP, 573, 573 ATPlike, Type3, Allosteric 66 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXMC 2.42 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type1 43 - 376 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7PQVA 2.13 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 80C Type1 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ZLSA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 92P Type1 39 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ZLXA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5EZ Type1 39 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ZM4A 2.37 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 22T Type1 40 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5BX0A 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 4W5 Type1 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7XNCA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo GIK Type1 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ZLYA 2.11 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo YSO Type1 40 - 382 0 None S298N,S299N,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5EYMA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 5EYMB 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQFA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo KSA Type1 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UB 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type1 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3ZLWA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo MT8 Type1 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXHA 2.81 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 39 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXHB 2.81 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXMA 2.42 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXXA 2.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 41 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXXC 2.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 37 - 378 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AYAB 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 42 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AYAD 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno A1AHE, ANP Type1, ATPlike 39 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AY7B 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 33 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UH 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VB 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VH 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7XLPA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno FZC Type1.5_Back 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7MFDB 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O2ZB 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXCB 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXCD 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UD 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UF 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4AN2A 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo EUI, ACP Type3, ATPlike 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4ANBA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YQY, ACP Type3, ATPlike 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 2P55A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo MRA, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4U7ZA 2.805 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_onoo 3EW, ANP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4U81A 2.701 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo 3EY, ANP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3V01A 2.705 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo 3V0, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3V04A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo V04, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQCA 1.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 3BM, AGS Type3, ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 3EQHA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5BM, ADP Type3, ATPlike 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9ECUB 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1BIS, ANP Type3, ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXYB 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type3, ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VD 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type3, ATPlike 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0VF 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type3, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0TB 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo 3EW, ANP Type3, ATPlike 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 7M0UB 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo QO7, ANP Type3, ATPlike 43 - 385 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K2 MP2K2_HUMAN 1S9IA 3.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo ATP, 5EA ATPlike, Type3 60 - 393 0 None None Dual specificity mitogen-activated protein kinase kinase 2
STE MAP2K2 MP2K2_HUMAN 1S9IB 3.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ATP, 5EA ATPlike, Type3 59 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 2
STE MAP2K4 MP2K4_HUMAN 3ALNA 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 83 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 3ALNB 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 84 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 3ALOA 2.6 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoao APEdist_oooo ANP ATPlike 95 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN 8YP5A 2.5 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoai APEdist_oooo 1FM Type1 80 - 392 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K7 MP2K7_HUMAN 7OVJA 2.35 Inactive DFGin‑BLBplus na-na none-none nonTYR APEdihe_aaiai APEdist_nnni 24N Type1.5_Front 102 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP4K4 M4K4_HUMAN 4U40A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U42A 2.504 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3C8 Type1 16 - 310 0 None T181E Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4ZP5A 2.29 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 4QG Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 5DI1A 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 5DF Type1 13 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 5J95A 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6HH Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4RVTA 2.4 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 3XM Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4OBOA 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 2QV Type1 16 - 310 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4OBQA 2.19 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_iioo 2QT Type1 16 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U41A 2.2 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3C8 Type1 16 - 310 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U43A 2.18 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo 3D8 Type1 14 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 5W5QA 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9X4 Type1.5_Back 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE PAK1 PAK1_HUMAN 4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZY5B 2.35 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T5 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 6B16B 2.285 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno C7Y Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 5DEWB 1.9 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59N Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9D4VB 1.84 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2P Type1 252 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9D4WB 2.218 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2Q Type1 257 - 545 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9NBXB 2.15 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BW5 Type1 254 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK2 PAK2_HUMAN 9LBFB 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 93 - 522 0 None D368N Serine/threonine-protein kinase PAK 2
STE PAK2 PAK2_HUMAN 9D51B 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2Q Type1 231 - 522 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2
STE STK24 STK24_HUMAN 8QLQA 1.64 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo VY0 Type1 26 - 301 0 None None Serine/threonine-protein kinase 24
STE TNIK TNIK_HUMAN 5CWZA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5CWZB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5CWZC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 15 - 308 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5D7AA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 310 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5D7AB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 5D7AC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 58C Type1 13 - 310 0 None None TRAF2 and NCK-interacting protein kinase
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFDA 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFEA 4.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9O2ZA 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYOA 3.74 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 334 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 331 - 631 0 None None LIM domain kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP8A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VNOA 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP6A 3.47 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP7A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL MAP3K12 M3K12_HUMAN 5CEOA 2.28 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50D Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CEPA 1.99 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50E Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CEQA 1.911 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50F Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5VO1A 2.45 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FS Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5VO2A 2.96 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FV Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OURA 1.95 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W38 Type1 118 - 396 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OUSA 2.2 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3I Type1 118 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OUTA 1.935 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3C Type1 118 - 399 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 9CDYA 1.5 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaooi APEdist_nnoo A1AZ8 Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8DEGA 2.79 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno SIQ Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21
TKL MAP3K7 M3K7_HUMAN 4L52A 2.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1UL Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4L53A 2.55 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1UO Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K9 M3K9_HUMAN 4UY9A 2.81 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 135 - 447 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN 4UY9B 2.81 Inactive DFGin‑BLBplus in-none out-out nonTYR APEdihe_aaoni APEdist_oooo No_ligand No_ligand 135 - 449 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN 3DTCA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaini APEdist_nnno VIN Type1 136 - 405 0 None T312A Mitogen-activated protein kinase kinase kinase 9
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RIPK2 RIPK2_HUMAN 5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TYR ABL1 ABL1_HUMAN 8SSNB 2.86 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1 64 - 506 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8SSNA 2.86 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1.5_Back 64 - 507 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TB 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 230 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 507 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TD 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 229 - 502 0 None None Tyrosine-protein kinase ABL1
TYR BMX BMX_HUMAN 8X2AA 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao LTJ Type1 411 - 671 0 None None Cytoplasmic tyrosine-protein kinase BMX
TYR BTK BTK_HUMAN 1K2PB 2.1 Inactive DFGin‑BLBplus out-out in-out TYR APEdihe_iioao APEdist_aaai No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8YVVA 2.25 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8YVVB 2.25 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3P08A 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3P08B 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IA 3.8 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 393 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IB 3.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMA 2.03 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMB 2.03 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6AUBA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BXM Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6S90A 1.82 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6S90B 1.82 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYA 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYB 2.31 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nooai APEdist_aaao 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5JRSA 1.97 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 6MV Type1 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5JRSB 1.97 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nooai APEdist_aaao 6MV Type1 396 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5T18A 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 73T Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXNA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9P Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXOA 1.94 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7LTYA 1.69 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao YD7 Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7LTZA 1.53 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao YDA Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXLA 1.84 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9J Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4A 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 395 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4B 2.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4C 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4D 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4E 2.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4F 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6O8IA 1.42 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao LTJ Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4QA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0B9 Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4RA 1.62 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 0BG Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4SA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0B0 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RX5A 1.356 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3YO Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5KUPA 1.389 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 6XL Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5VGOA 1.621 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9B1 Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXQA 1.38 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9Y Type1 390 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3OCSA 1.8 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTFA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2VL Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4ZLYA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4RU Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4ZLZA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4RV Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8GC7A 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao YXJ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8U2DA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UQX Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8U2EA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UP9 Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5U9DA 1.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 83P Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5VFIA 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI0A 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJG Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI1A 1.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJD Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI9A 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao GJJ Type1 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NFHA 1.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KLM Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXMA 1.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9M Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXPA 1.83 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9V Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PIXA 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao 027 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87A 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87B 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 385 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87C 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87D 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 385 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPC 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPD 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 392 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPE 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9FA 1.71 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2VL Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9GA 1.75 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7G6 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9HA 1.95 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 7G7 Type1 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9KA 1.28 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7G8 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9LA 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 7G9 Type1 392 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6AUAA 1.66 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BXJ Type1 394 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NZMA 1.72 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NZMD 1.72 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BQ0A 1.57 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 4US Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLHA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y8H Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLVA 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ZB9 Type1 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao UEO Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU4A 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao V72 Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU5A 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao V7I Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4Z3VA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4L6 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5OA 1.25 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0BQ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5RA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0UW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5XA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0GW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5YA 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0CI Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BIKA 1.901 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DTJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKEA 1.95 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DVJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKHA 1.792 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DVD Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BLNA 1.3 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DY4 Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6XE4A 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao V1G Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6VXQA 1.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao RQS Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W06A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao S5M Type1 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W07A 1.51 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao S9A Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLGA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y8C Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OT5A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 481 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OT6A 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V1 Type1 394 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTQA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V2 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTRA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V3 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RFYA 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3OU Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RFZA 1.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3OV Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RG0A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3P0 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6EP9A 2.01 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BNB Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6HRPA 1.12 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GMQ Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6HRTA 1.36 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GMW Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8GC8A 1.75 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao YXJ Type1 392 - 658 0 None L528W Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8EJBA 1.58 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao WKC, PD Type1, Allosteric 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3NA 1.95 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ULV, 5WE Type1, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKWA 1.499 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao DXM, FPZ Type1, Type1 393 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6J6MA 1.25 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BA0 Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R61A 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2IJ Type1.5_Back 390 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI3A 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJA Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI5A 1.42 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJ7 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6N9PA 2.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KHD Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6OMUA 1.41 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao MZJ Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R60A 1.94 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2IE Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8E2MA 1.904 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UB6 Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OA 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TL7 Type1.5_Back 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OB 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TL7 Type1.5_Back 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IC 3.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TKY Type1.5_Back 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8DSOB 2.334 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_iooai APEdist_aaao TOO Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFA 2.2 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 4C9 Type1.5_Back 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFB 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4C9 Type1.5_Back 390 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9IA 1.11 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E8 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9JA 1.08 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 8E8 Type1.5_Back 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9MA 1.41 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7GB Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3GENA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao B43 Type1.5_Back 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6E4FA 1.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao HRA Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBOA 1.894 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao 5WH, 5WE Type1.5_Back, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLNA 1.334 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBNC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 5WF, 5WE Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OB 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLLA 1.498 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBND 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 5WF, 5WE, 5WE, 5WE Type1.5_Front, Allosteric, Allosteric, Allosteric 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3PA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UM4, UM4, BTB Type1.5_Front, Allosteric, Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR EGFR EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 698 - 1015 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1014 0 None I706Q Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DB 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP, NQ1 ATPlike, Type3 702 - 1013 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LA 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LC 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LD 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 702 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, O57 ATPlike, Type3 699 - 1019 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai AMP, O57 ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AMP, O57 ATPlike, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai AMP, O57 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4D 2.06 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, NQ1 ATPlike, Type3 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5D41A 2.31 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, 57N ATPlike, Type3 698 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP, JBJ ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMD 2.192 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, 9LL ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPA 2.16 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB 2.16 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD 2.16 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF 2.16 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP, VNS ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, VNS ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXA 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXB 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXC 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXD 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YW5 ATPlike, Type3 700 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, VNS ATPlike, Type3 700 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNA 1.76 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWA 2.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7TVDA 2.96 Inactive DFGin‑BLBplus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 698 - 1009 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5ZTOA 2.649 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 9JO Type1 697 - 1017 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao QQM Type1 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5NA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP7 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5PA 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP4 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai VO7 Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KY0A 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai XA4 Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFYA 1.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao N7Z Type1 699 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6JB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao R2E Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYQA 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao V58 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5FEEA 2.7 Inactive DFGin‑BLBplus in-in in-out TYR APEdihe_iioao APEdist_aaai 5X4 Type1 697 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYA 3.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 816 Type1 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYC 3.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYF 3.14 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4A 2.06 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai Q6K, NQ1 Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMB 2.192 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai YY3, 9LL Type1, Type3 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, YW5 Type1, Type3 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4BA 2.5 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao Q6K, 9LL Type1, Type3 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4BB 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, 9LL Type1, Type3 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao 8BS, 57N Type1, Type3 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 80U Type1.5_Back 697 - 985 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao TOV Type1.5_Back 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai YAA Type1.5_Back 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai N7K Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_niiai APEdist_aaai N7Q Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai N7Q Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai N7W Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N7W Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N7Z Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_niiai APEdist_aaai N7B Type1.5_Back 701 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai N7B Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai N78 Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai N78 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N82 Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao N82 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_ooiai APEdist_aaao HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 699 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 700 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai HYZ Type1.5_Back 702 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai POX Type1.5_Back 702 - 1015 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 26X Type1.5_Back 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 704 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 03P Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai W19 Type1.5_Back 701 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao FMM Type1.5_Back 702 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 2EI Type1.5_Back 699 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 26X Type1.5_Back 705 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 26X Type1.5_Back 702 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai A1H7N Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao A1IUK Type1.5_Back 702 - 986 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_iiiai APEdist_aaao A1IUK Type1.5_Back 702 - 985 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC 2.4 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao TQA Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNC 1.76 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao UEJ Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXND 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai UEJ Type1.5_Front 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao IXC Type1.5_Front 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao VNS, 8RC Type1.5_Front, Type1 702 - 1002 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao 9LL Type3 702 - 985 0 None T790M,C797S,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DC 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai NQ1, ANP Type3, ATPlike 702 - 1006 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai NQ1, ANP Type3, ATPlike 701 - 1008 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4B 2.06 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai NQ1, Q6K Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC 2.16 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE 2.16 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 703 - 1004 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 702 - 1003 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 701 - 1008 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 703 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR ERBB2 ERBB2_HUMAN 7JXHE 3.27 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VOY Type1.5_Back 709 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 6OP9A 2.501 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oiiai APEdist_aaai DB8 Type1 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB4 ERBB4_HUMAN 3BBWA 4.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 708 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBWB 4.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 2R4BA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 2R4BB 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTB 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan FMM Type1.5_Back 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTD 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan FMM Type1.5_Back 709 - 988 0 None None Receptor tyrosine-protein kinase erbB-4
TYR FGFR1 FGFR1_HUMAN 8JQIB 4.1 Inactive DFGin‑BLBplus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 463 - 769 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8YKIA 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8YKIB 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLB 2.8 Inactive DFGin‑BLBplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XZ7A 1.75 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1 458 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nioai APEdist_aaao LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR3 FGFR3_HUMAN 8UDUA 1.737 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iiiai APEdist_aaao WIQ Type1.5_Back 460 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR4 FGFR4_HUMAN 8KH9A 1.42 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 454 - 752 0 None C477A,V550M,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus in-out none-none TYR APEdihe_nniai APEdist_aaai 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGR FGR_HUMAN 7UY0A 2.55 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN 7UY0B 2.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR HCK HCK_HUMAN 5ZJ6A 1.696 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1 248 - 518 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 1QCFA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao PP1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS2A 2.609 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSB Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS5A 2.851 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS5B 2.851 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS7B 3.001 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan KS1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDA 2.85 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SK8 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDB 2.85 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SK8 Type1 81 - 524 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0GA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOU Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5ZJ6B 1.696 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1.5_Back 249 - 518 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 9BYJA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYA 2.481 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYB 2.481 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3A 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3B 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4A 2.747 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4B 2.747 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6A 2.373 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6B 2.373 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEA 3.04 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEB 3.04 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H09A 1.945 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOO Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0BA 1.651 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOQ Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0EA 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOS Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0HA 1.72 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOV Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR ITK ITK_HUMAN 1SNXA 3.2 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNXB 3.2 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3MJ2A 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao MJG Type1 357 - 615 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPAA 2.67 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPAB 2.67 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPBA 2.82 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPBB 2.82 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4QD6B 2.45 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SM2A 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNUA 2.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCTA 1.48 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 18R Type1 354 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCUA 1.43 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 13L Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCVA 1.48 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 13J Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 9NWXA 1.348 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1B66 Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3T9TA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao IAQ Type1 356 - 618 0 None F435T,K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M0YA 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao M0Y, M0Y Type1, Type3 356 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M14A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QWS, QWS Type1, Type3 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M12A 2.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1YZ Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M13A 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E0 Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M15A 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QWS, ADP Type3, ATPlike 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M0ZA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao M0Z, M0Z Type3, Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR KDR VGFR2_HUMAN 3WZDA 1.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao LEV Type1 820 - 1167 0 None T940V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8RA 2.7 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 887 Type1 818 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8RB 2.7 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 887 Type1 821 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR LCK LCK_HUMAN 3MPMA 1.95 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_nnoai APEdist_aaao 5LK Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 4C3FA 1.72 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_nniai APEdist_aaao 7KW Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck
TYR MERTK MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7DXLA 3.146 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nnoai APEdist_aaao E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7DXLB 3.146 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRA 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRB 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRC 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRD 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4M3QB 2.718 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4MHAA 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 580 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0KA 2.545 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0XA 2.231 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AVXA 2.44 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai S4K Type1.5_Front 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 3DKCA 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ATP ATPlike 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2G15A 2.15 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1046 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 1R1WA 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU3A 2.26 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao 3E8 Type1 1052 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU3B 2.26 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao 3E8 Type1 1056 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU5A 2.72 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1067 - 1346 0 None F1200I Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AW1A 2.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 3E8 Type1 1066 - 1345 0 None Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AW1B 2.14 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1064 - 1345 0 None Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBA 2.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 1RU Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBB 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 1RU Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBC 2.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 1RU Type1 1060 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 1RU Type1 1064 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4R1VA 1.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WD1A 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai ZZY Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4R1YA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3EH Type1 1062 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F66A 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai IHX Type1 1052 - 1349 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F66B 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai IHX Type1 1062 - 1349 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3QA 1.75 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SV5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3TA 2.23 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai SVK Type1 1062 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3VA 1.93 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SWB Type1 1057 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3WA 2.02 Inactive DFGin‑BLBplus none-none out-in TYR APEdihe_iiiai APEdist_aaai SVH Type1 1067 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3ZA 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SV8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B40A 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SWN Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B41A 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SWK Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B42A 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SW8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B43A 1.87 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SW5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B43B 1.87 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SW5 Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B44A 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SVT Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WGJA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai VGH Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WKMA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai PFY Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZBXA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 6XE Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZC5A 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai W9Z Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZCLA 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5TF Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZXZA 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai KRW Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZZEA 1.87 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 6XP Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4AOIA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 4K0 Type1 1052 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4AP7A 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai F47 Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDEA 2.49 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai V0L Type1 1068 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7Y4TA 2.16 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai I90 Type1 1063 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7Y4UA 2.26 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai I94 Type1 1061 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8GVJA 2.71 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai KGL Type1 1060 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8K78A 2.67 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai IYC Type1 1048 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9IVBA 2.35 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1L3A Type1 1040 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9IVBB 2.35 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1L3A Type1 1045 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3I5NA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai B2D Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEGA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JJ Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEHA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JK Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEIA 2.05 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JL Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4XMOA 1.75 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 46G Type1 1051 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4XYFA 1.85 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 44X Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EYCA 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5SZ Type1 1053 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EYDA 1.85 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5T1 Type1 1052 - 1348 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2RFSA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AM8 Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CCNA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai LKG Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CD8A 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai L5G Type1 1054 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4GG5A 2.423 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai 0J3 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4GG7A 2.27 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0J8 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EOBA 1.75 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5QQ Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5YA5A 1.89 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai 6TD Type1 1057 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5UABA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84M Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5UADA 2.25 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84P Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6UBWA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84S Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3DKGA 1.91 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai SX8 Type1 1050 - 1356 0 None Y1194F,Y1230L,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 1R0PA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KSA Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HNIX 1.71 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HNIY 1.71 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HO6A 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 63K Type1 1063 - 1356 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3QTIA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3QT Type1 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3QTIB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3QT Type1 1058 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3DKFA 1.8 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_niiai APEdist_aaai SX8 Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3A4PA 2.54 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai DFQ Type1 1063 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HOAA 2.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 63K Type1 1065 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HORA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 63K Type1 1064 - 1356 0 None Y1194F,Y1234F,Y1235D,M1250T Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3U6HA 2.0 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 03X Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3U6IA 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 044 Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor
TYR MST1R RON_HUMAN 3PLSA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 1060 - 1357 0 None M1254T Macrophage-stimulating protein receptor
TYR MST1R RON_HUMAN 8ZKDA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao ANP ATPlike 1060 - 1357 0 None None Macrophage-stimulating protein receptor
TYR PTK6 PTK6_HUMAN 5D7VA 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VB 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VC 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VD 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 6CZ2A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao No_ligand No_ligand 182 - 443 0 PTR342 None Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UB 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UC 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UD 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5DA3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 58V Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 6CZ3A 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao FLJ Type1 182 - 443 0 None None Protein-tyrosine kinase 6
TYR SRC SRC_HUMAN 2SRCA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 87 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 9IRLA 2.031 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1L20 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JN8A 1.902 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao JA6 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JN9A 2.724 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao UJ0 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2H8HA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao H8H Type1 88 - 532 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4K11A 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0J9 Type1 87 - 534 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1KSWA 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao NBS Type1 87 - 536 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7NG7A 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao UCW Type1.5_Back 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SYK KSYK_HUMAN 4FL3A 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 9 - 635 0 None Y348F,Y352F Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FL2A 2.19 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 9 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3TUCA 2.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan FPW Type1.5_Front 358 - 633 0 None None Tyrosine-protein kinase SYK
TYR TEK TIE2_HUMAN 3L8PA 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 0CE Type1 814 - 1121 0 None None Angiopoietin-1 receptor
TYR TNK2 ACK1_HUMAN 4HZSA 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4HZSB 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4HZSC 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4HZSD 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1

All / BLBplus / All

Total number of chains: 1014
Active chains: 0
Total number of genes: 71
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1014 100.0% 6DI1A
All chains
No PyMOL session because the query has >1000 chains
Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TYR BTK Q3ZC95_BOVIN 4Y95A 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95D 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y93A 1.695 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 1 - 658 0 None L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95B 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746, PE4 Type1, Allosteric 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95C 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746, PE4 Type1, Allosteric 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR LET23 LET23_CAEEL 5WNOA 2.386 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nooai APEdist_aaao ANP ATPlike 876 - 1190 0 None None Receptor tyrosine-protein kinase let-23 Caenorhabditis elegans
CAMK CDPK1 A3FQ16_CRYPI 3IGOA 2.25 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 4Y5QA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo AMP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9D8SA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AMP ATPlike 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 3MWUA 1.98 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo BK3 Type1 70 - 536 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 3NCGA 2.49 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo BK1 Type1 70 - 533 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9MI4A 2.94 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo A1BLB Type1 70 - 535 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9MI5A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BLC Type1 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
STE DSOR1 DSOR1_DROME 8BW9C 3.32 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 81 - 384 0 None None Dual specificity mitogen-activated protein kinase kinase dSOR1 Drosophila melanogaster
TYR SRC SRC_CHICK 5BMMA 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5BMMB 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 2PTKA 2.35 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 83 - 528 0 PTR527 None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBKA 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 4B7 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7RA 2.0 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 53 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 2HW7A 2.71 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno STU Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CJ5A 2.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4G Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CJEA 3.36 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4A Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CJHA 3.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno ET8 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CJWA 3.38 Inactive DFGin‑BLBplus out-in none-out nonTYR APEdihe_aaoii APEdist_nnno FYV Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CJYA 3.05 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F4J Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CK3A 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno F67 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CK6A 3.32 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno N45 Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 6CKIA 2.95 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno FZJ Type1 72 - 371 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 9HRCA 3.161 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo A1IWO Type1 72 - 375 0 None D228G MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CMGC CDK1 CDK1_HUMAN 4YC6A 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 4YC6C 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 4YC6E 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 4YC6G 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 6GU7C 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 6GU7E 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 6GU7G 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK1 CDK1_HUMAN 6GU7A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno FB8 Type1 1 - 293 0 None None Cyclin-dependent kinase 1 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4FKUA 1.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 60K, 60K Allosteric, Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1AQ1A 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nooo STU Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1DI8A 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DTQ Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1FVTA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 106 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GIHA 2.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 1PU Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1JVPP 1.53 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 89E Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1KE5A 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo LS1 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1KE6A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno LS2 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1KE7A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo LS3 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1KE8A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo LS4 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1KE9A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo LS5 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1R78A 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno FMD Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2XNBA 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo Y8L Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4BGHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3I6 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5IEVA 2.03 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo R0N Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4FKWA 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 62K Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7NVQA 2.05 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo STU Type1 1 - 294 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6Q4HA 1.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo HGH Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GIIA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1PU Type1 1 - 298 0 None F82H,L83V,K89T Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK4 CDK4_HUMAN 6P8GB 2.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 18 - 299 0 None G43E,G47E Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 6P8HB 3.19 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 18 - 298 0 None None Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 2W99B 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 2 - 295 0 None G43E,G47E,T172A Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 2W9ZB 2.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 2 - 295 0 None G43E,G47E,T172A Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 2W96B 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 4 - 295 0 None G43E,G47E,T172D Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 9CSKB 2.253 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo A1AZ4 Type1 4 - 295 0 None G43E,G47E Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK4 CDK4_HUMAN 9CSKD 2.253 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo A1AZ4 Type1 4 - 295 0 None G43E,G47E Cyclin-dependent kinase 4 Homo sapiens
CMGC CDK6 CDK6_HUMAN 1BLXA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 5 - 309 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 6OQLA 2.707 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1A Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 6OQOA 1.977 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno N1J Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 8I0MA 2.777 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno NJ6 Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 3NUPA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3NU Type1 12 - 300 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 3NUXA 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 3NV Type1 10 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 4AUAA 2.31 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4AU Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 4EZ5A 2.7 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0RS Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 5L2IA 2.75 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LQQ Type1 10 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 5L2SA 2.27 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZV Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 5L2TA 2.37 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 6ZZ Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 9D8UA 2.0 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno A1AZ4 Type1 11 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 9PE7A 2.05 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo A1CIF Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 9PE8A 1.8 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_nooo A1AZ4 Type1 10 - 301 0 None E21V,K26T,T106R,Q149E Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8P4ZB 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno WZ8 Type1 10 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5HBHA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 5Y7 Type1 1 - 361 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4H36A 3.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4H3BA 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4H3BC 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK12 MK12_HUMAN 6UNAA 2.554 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 10 - 351 0 None Q31R Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK12 MK12_HUMAN 6UNAB 2.554 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 351 0 None Q31R Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK13 MK13_HUMAN 8X23A 1.5 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 1 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK13 MK13_HUMAN 4YNOA 1.7 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 2 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK13 MK13_HUMAN 3COIA 2.09 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooo APEdist_nnoo No_ligand No_ligand 2 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK13 MK13_HUMAN 4EYMA 2.353 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 0RX Type1 2 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK13 MK13_HUMAN 5EKOA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo N17 Type1 2 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NEWA 2.51 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 3NE Allosteric 5 - 352 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OK Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MH2A 2.3 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 5 - 352 0 None F169Y Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5ETIA 2.8 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FI4A 2.2 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FI4 Type1 4 - 352 0 None R57K Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FKOA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FKO Type1 5 - 352 0 None R57K Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLNC 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 3FN Type1 3 - 352 0 None R57K Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6OHDA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno MKP Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1OVEA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 358 Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GC7A 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo B45 Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3S3IA 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo CQ0 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1ZZLA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo TZY Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2YIXA 2.3 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo YIX Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HRBA 2.2 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo I39 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1ZYJA 2.0 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BI5 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1ZZ2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno B11 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ZAZA 1.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK1 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3D7ZA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK5 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3IPHA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo G11 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3KF7A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nnoo L9G Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3RINA 2.2 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo I2O Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5MTXA 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn FJI Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5MTYA 2.31 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn HB9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5TBEA 2.44 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 78L Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 9Y8BA 1.97 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioo APEdist_nnno A1CTD Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5TCOA 2.1 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 79Q Type1 6 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 9Q5BA 2.05 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno A1CRZ Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6M9LA 2.45 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn J9G Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3DS6A 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3DS6B 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3DS6C 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3DS6D 2.9 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo A17 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GFEA 2.1 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P37 Type1 1 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3ITZA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P66 Type1 1 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LHJA 3.31 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LHJ Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3U8WA 2.15 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 09J Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2BALA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno PQA Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4AA4A 2.3 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo QC0 Type1 5 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4AA5A 2.38 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo NQB Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4AACA 2.5 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo AAV Type1 5 - 359 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2QD9A 1.7 Inactive DFGin‑BLBplus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn LGF Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MVLA 2.8 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 38P Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MVLB 2.8 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 38P Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MVMA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 39P Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MVMB 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanoo APEdist_nnnn 39P Type1 5 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NWWA 2.09 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 3NW Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3S4QA 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno NK0 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KINA 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioo APEdist_nooo 1M8 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KINB 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo 1M8 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KINC 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1M8 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIND 1.97 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1M8 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIPA 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1R9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIPB 2.27 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 1R9 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIQA 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaini APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIQB 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaino APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIQC 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaini APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4KIQD 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaino APEdist_nnno 1RA Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FKLA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FKL Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FKNA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FKN Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FL4A 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FL4 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLSA 2.3 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLWA 2.1 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FLW Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLYA 1.8 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLY Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLZA 2.23 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FLZ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FMHA 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 533 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FMKA 1.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo FMK Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FMMA 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo XI2 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FMNA 1.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 530 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3E92A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo G6A Type1 3 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MPTA 1.89 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 1GK Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3DT1A 2.8 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P40 Type1 1 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4F9YA 1.85 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo LM3 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HL7A 1.88 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nnno I47, I46 Type1, Allosteric 6 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3ROCA 1.7 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaoni APEdist_nnoo 29A, 29B Type1, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HLLA 1.95 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaoni APEdist_nnoo I45, I46, PO2 Type1, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2I0HA 2.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 222, 222 Type1, Type1 4 - 352 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2RG5A 2.4 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 279 Type1.5_Back 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3BX5A 2.4 Inactive DFGin‑BLBplus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 304 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3L8XA 2.4 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno N4D Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2RG6A 1.72 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno 287, 287 Type1.5_Back, Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9N88A 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9N88E 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W39A 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W39B 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3AA 2.606 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3AB 2.606 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6NT9A 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6NT9B 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 5W5VA 3.645 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANW Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6BODA 3.197 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn E0P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6RSTA 3.29 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHQ Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IWOA 2.61 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1H4 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM2A 2.5 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM3A 3.342 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQDA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQIA 1.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5YT3C 2.9 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 40 - 382 0 None S218D,S222D,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6U2GA 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6V2WB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4MNEA 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type1 63 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4MNED 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type1 66 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 8DGSB 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo AGS, LCJ ATPlike, Type1 38 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4AN3A 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_onno ATP, 5Y0 ATPlike, Type3 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4AN9A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_onoo ACP, 2P7 ATPlike, Type3 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3SLSA 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nooo ANP, 77D ATPlike, Type3 45 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3SLSB 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nooo ANP, 77D ATPlike, Type3 45 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B3MA 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ANP, SU5 ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B3MB 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ANP, SU5 ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B7RA 1.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ANP, T1K ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B7RB 1.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, T1K ATPlike, Type3 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B94A 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ANP, T3W ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B94B 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, T3W ATPlike, Type3 41 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B9LA 1.7 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP, T4N ATPlike, Type3 37 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7B9LB 1.7 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP, T4N ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ORNA 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3OR ATPlike, Type3 62 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3OS3A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, 3OS ATPlike, Type3 62 - 378 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3WIGA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, CHU ATPlike, Type3 62 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3DV3A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno ATP, MEK ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3MBLA 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, LSG ATPlike, Type3 62 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3PP1A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, IZG ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQBA 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo ATP, LUG ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4U80A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo ANP, 3EX ATPlike, Type3 62 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 1S9JA 2.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo ATP, BBM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3DY7A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnno ATP, 1CX ATPlike, Type3 62 - 364 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3E8NA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_onoo ATP, VRA ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3VVHA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn ATP, 4BM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3VVHB 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ATP, 4BM ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3VVHC 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP, 4BM ATPlike, Type3 62 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4ARKA 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, M3K ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4LMNA 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4MNEE 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ACP, 573 ATPlike, Type3 62 - 379 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQGA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ADP, 4BM ATPlike, Type3 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7UMBC 3.231 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, U9F ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6PP9B 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, LCJ ATPlike, Type3 38 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0VB 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0WB 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOA ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0XB 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0YB 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 43 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0ZB 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, CHU ATPlike, Type3 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 8DGTB 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo AGS, LCJ ATPlike, Type3 43 - 385 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 6NYBB 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP, LCJ ATPlike, Type3 56 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9MMPB 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9MMQB 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9MMRB 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 62 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9MMSB 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo AGS, LCJ ATPlike, Type3 63 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4MNEH 2.848 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo ACP, 573, 573 ATPlike, Type3, Allosteric 66 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXMC 2.42 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type1 43 - 376 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7PQVA 2.13 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 80C Type1 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ZLSA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 92P Type1 39 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ZLXA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5EZ Type1 39 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ZM4A 2.37 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 22T Type1 40 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5BX0A 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 4W5 Type1 39 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7XNCA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo GIK Type1 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ZLYA 2.11 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo YSO Type1 40 - 382 0 None S298N,S299N,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5EYMA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 5EYMB 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 41 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQFA 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo KSA Type1 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UB 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type1 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3ZLWA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo MT8 Type1 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXHA 2.81 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 39 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXHB 2.81 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXMA 2.42 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 38 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXXA 2.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 41 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXXC 2.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 37 - 378 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AYAB 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 42 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AYAD 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnno A1AHE, ANP Type1, ATPlike 39 - 382 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AY7B 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type1, ATPlike 33 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UH 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0VB 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0VH 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU, ANP Type1, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7XLPA 2.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno FZC Type1.5_Back 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7MFDB 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O2ZB 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXCB 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXCD 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UD 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UF 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4AN2A 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo EUI, ACP Type3, ATPlike 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4ANBA 2.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YQY, ACP Type3, ATPlike 61 - 381 0 None S218E,S222E,G328A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 2P55A 2.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo MRA, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4U7ZA 2.805 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_onoo 3EW, ANP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 4U81A 2.701 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo 3EY, ANP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3V01A 2.705 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo 3V0, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3V04A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_nnoo V04, ATP Type3, ATPlike 62 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQCA 1.8 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 3BM, AGS Type3, ATPlike 39 - 382 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 3EQHA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5BM, ADP Type3, ATPlike 39 - 381 0 None S298N,S299K,Y300F Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9ECUB 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1BIS, ANP Type3, ATPlike 43 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXYB 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE, ANP Type3, ATPlike 40 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0VD 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type3, ATPlike 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0VF 3.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU, ANP Type3, ATPlike 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0TB 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo 3EW, ANP Type3, ATPlike 42 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7M0UB 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo QO7, ANP Type3, ATPlike 43 - 385 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K2 MP2K2_HUMAN 1S9IA 3.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo ATP, 5EA ATPlike, Type3 60 - 393 0 None None Dual specificity mitogen-activated protein kinase kinase 2 Homo sapiens
STE MAP2K2 MP2K2_HUMAN 1S9IB 3.2 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn ATP, 5EA ATPlike, Type3 59 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 2 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALNA 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 83 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALNB 2.3 Inactive DFGin‑BLBplus na-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 84 - 390 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 3ALOA 2.6 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoao APEdist_oooo ANP ATPlike 95 - 389 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 8YP5A 2.5 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaoai APEdist_oooo 1FM Type1 80 - 392 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 7OVJA 2.35 Inactive DFGin‑BLBplus na-na none-none nonTYR APEdihe_aaiai APEdist_nnni 24N Type1.5_Front 102 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U40A 2.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U42A 2.504 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3C8 Type1 16 - 310 0 None T181E Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4ZP5A 2.29 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 4QG Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 5DI1A 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 5DF Type1 13 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 5J95A 2.5 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6HH Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4RVTA 2.4 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 3XM Type1 14 - 309 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4OBOA 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 2QV Type1 16 - 310 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4OBQA 2.19 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_iioo 2QT Type1 16 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U41A 2.2 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 3C8 Type1 16 - 310 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U43A 2.18 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo 3D8 Type1 14 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE MAP4K4 M4K4_HUMAN 5W5QA 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9X4 Type1.5_Back 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZY5B 2.35 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T5 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 6B16B 2.285 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno C7Y Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 5DEWB 1.9 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59N Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9D4VB 1.84 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2P Type1 252 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9D4WB 2.218 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2Q Type1 257 - 545 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9NBXB 2.15 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BW5 Type1 254 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK2 PAK2_HUMAN 9LBFB 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 93 - 522 0 None D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
STE PAK2 PAK2_HUMAN 9D51B 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2Q Type1 231 - 522 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2 Homo sapiens
STE STK24 STK24_HUMAN 8QLQA 1.64 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo VY0 Type1 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE TNIK TNIK_HUMAN 5CWZA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5CWZB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5CWZC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 15 - 308 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5D7AA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 310 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5D7AB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 5D7AC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 58C Type1 13 - 310 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFDA 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFEA 4.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9O2ZA 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYOA 3.74 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 334 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 331 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP8A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VNOA 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP6A 3.47 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP7A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEOA 2.28 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50D Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEPA 1.99 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50E Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEQA 1.911 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50F Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5VO1A 2.45 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FS Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5VO2A 2.96 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FV Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OURA 1.95 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W38 Type1 118 - 396 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OUSA 2.2 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3I Type1 118 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OUTA 1.935 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3C Type1 118 - 399 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 9CDYA 1.5 Inactive DFGin‑BLBplus na-na out-out nonTYR APEdihe_aaooi APEdist_nnoo A1AZ8 Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8DEGA 2.79 Inactive DFGin‑BLBplus na-na none-out nonTYR APEdihe_aaooi APEdist_nnno SIQ Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L52A 2.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1UL Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L53A 2.55 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1UO Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 4UY9A 2.81 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 135 - 447 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 4UY9B 2.81 Inactive DFGin‑BLBplus in-none out-out nonTYR APEdihe_aaoni APEdist_oooo No_ligand No_ligand 135 - 449 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 3DTCA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaini APEdist_nnno VIN Type1 136 - 405 0 None T312A Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TYR ABL1 ABL1_HUMAN 8SSNB 2.86 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1 64 - 506 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 8SSNA 2.86 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1.5_Back 64 - 507 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G1TA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G1TB 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 230 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G1TC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 507 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G1TD 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 229 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR BMX BMX_HUMAN 8X2AA 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao LTJ Type1 411 - 671 0 None None Cytoplasmic tyrosine-protein kinase BMX Homo sapiens
TYR BTK BTK_HUMAN 1K2PB 2.1 Inactive DFGin‑BLBplus out-out in-out TYR APEdihe_iioao APEdist_aaai No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8YVVA 2.25 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8YVVB 2.25 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3P08A 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3P08B 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W8IA 3.8 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 393 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W8IB 3.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4NWMA 2.03 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4NWMB 2.03 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6AUBA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BXM Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6S90A 1.82 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6S90B 1.82 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5BPYA 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5BPYB 2.31 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nooai APEdist_aaao 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5JRSA 1.97 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 6MV Type1 396 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5JRSB 1.97 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nooai APEdist_aaao 6MV Type1 396 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5T18A 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 73T Type1 396 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXNA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9P Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXOA 1.94 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7LTYA 1.69 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao YD7 Type1 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7LTZA 1.53 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao YDA Type1 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXLA 1.84 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9J Type1 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4A 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 395 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4B 2.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4C 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4D 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4E 2.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5ZZ4F 2.9 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6O8IA 1.42 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao LTJ Type1 391 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N4QA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0B9 Type1 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N4RA 1.62 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 0BG Type1 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N4SA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0B0 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4RX5A 1.356 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3YO Type1 394 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5KUPA 1.389 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 6XL Type1 394 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5VGOA 1.621 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9B1 Type1 394 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXQA 1.38 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9Y Type1 390 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3OCSA 1.8 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4OTFA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2VL Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4ZLYA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4RU Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4ZLZA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4RV Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8GC7A 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao YXJ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8U2DA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UQX Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8U2EA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UP9 Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5U9DA 1.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 83P Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5VFIA 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI0A 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJG Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI1A 1.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJD Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI9A 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao GJJ Type1 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6NFHA 1.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KLM Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXMA 1.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9M Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7KXPA 1.83 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao X9V Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3PIXA 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao 027 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5J87A 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5J87B 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 385 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5J87C 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5J87D 1.59 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6TFPA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6TFPB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 385 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6TFPC 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6TFPD 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 392 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6TFPE 2.0 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9FA 1.71 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2VL Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9GA 1.75 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7G6 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9HA 1.95 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 7G7 Type1 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9KA 1.28 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7G8 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9LA 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 7G9 Type1 392 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6AUAA 1.66 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BXJ Type1 394 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6NZMA 1.72 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6NZMD 1.72 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5BQ0A 1.57 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 4US Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLHA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y8H Type1 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLVA 1.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ZB9 Type1 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8TU3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao UEO Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8TU4A 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao V72 Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8TU5A 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao V7I Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4Z3VA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4L6 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N5OA 1.25 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0BQ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N5RA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0UW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N5XA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0GW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7N5YA 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0CI Type1 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6BIKA 1.901 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DTJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6BKEA 1.95 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DVJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6BKHA 1.792 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DVD Type1 396 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6BLNA 1.3 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao DY4 Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6XE4A 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao V1G Type1 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6VXQA 1.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao RQS Type1 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W06A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao S5M Type1 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W07A 1.51 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao S9A Type1 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLGA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y8C Type1 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4OT5A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 481 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4OT6A 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V1 Type1 394 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4OTQA 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V2 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4OTRA 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2V3 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4RFYA 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3OU Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4RFZA 1.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3OV Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4RG0A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 3P0 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6EP9A 2.01 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BNB Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6HRPA 1.12 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GMQ Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6HRTA 1.36 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GMW Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8GC8A 1.75 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao YXJ Type1 392 - 658 0 None L528W Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8EJBA 1.58 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao WKC, PD Type1, Allosteric 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3NA 1.95 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ULV, 5WE Type1, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6BKWA 1.499 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao DXM, FPZ Type1, Type1 393 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6J6MA 1.25 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao BA0 Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7R61A 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2IJ Type1.5_Back 390 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI3A 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJA Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI5A 1.42 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao GJ7 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6N9PA 2.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KHD Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6OMUA 1.41 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao MZJ Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7R60A 1.94 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 2IE Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8E2MA 1.904 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UB6 Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W7OA 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TL7 Type1.5_Back 396 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W7OB 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TL7 Type1.5_Back 396 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W8IC 3.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao TKY Type1.5_Back 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8DSOB 2.334 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_iooai APEdist_aaao TOO Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4YHFA 2.2 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 4C9 Type1.5_Back 391 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4YHFB 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 4C9 Type1.5_Back 390 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9IA 1.11 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E8 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9JA 1.08 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 8E8 Type1.5_Back 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9MA 1.41 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 7GB Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3GENA 1.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao B43 Type1.5_Back 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6E4FA 1.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao HRA Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBOA 1.894 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao 5WH, 5WE Type1.5_Back, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLNA 1.334 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBNC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 5WF, 5WE Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3OA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3OB 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLLA 1.498 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBND 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 5WF, 5WE, 5WE, 5WE Type1.5_Front, Allosteric, Allosteric, Allosteric 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3PA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UM4, UM4, BTB Type1.5_Front, Allosteric, Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR EGFR EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 698 - 1015 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP ATPlike 699 - 1014 0 None I706Q Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1DB 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao ANP, NQ1 ATPlike, Type3 702 - 1013 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1LA 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1LC 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1LD 2.8 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, 9LL ATPlike, Type3 702 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, O57 ATPlike, Type3 699 - 1019 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai AMP, O57 ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AMP, O57 ATPlike, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai AMP, O57 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6XL4D 2.06 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, NQ1 ATPlike, Type3 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5D41A 2.31 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, 57N ATPlike, Type3 698 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKB 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKE 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP, JBJ ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6DUKF 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKD 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXMD 2.192 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, 9LL ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPA 2.16 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPB 2.16 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPD 2.16 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPF 2.16 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai ANP, VNS ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, VNS ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LTXA 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LTXB 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LTXC 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LTXD 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ANP, YW5 ATPlike, Type3 700 - 1012 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, VNS ATPlike, Type3 700 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WXNA 1.76 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7UKWA 2.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7TVDA 2.96 Inactive DFGin‑BLBplus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 698 - 1009 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5ZTOA 2.649 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 9JO Type1 697 - 1017 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao QQM Type1 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V5NA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP7 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V5PA 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP4 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai VO7 Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7KY0A 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai XA4 Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFYA 1.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao N7Z Type1 699 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7A6JB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao R2E Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7ZYQA 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao V58 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5FEEA 2.7 Inactive DFGin‑BLBplus in-in in-out TYR APEdihe_iioao APEdist_aaai 5X4 Type1 697 - 1018 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYA 3.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 816 Type1 700 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYC 3.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYF 3.14 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_nniai APEdist_aaao 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6XL4A 2.06 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai Q6K, NQ1 Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXMB 2.192 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai YY3, 9LL Type1, Type3 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, YW5 Type1, Type3 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6Z4BA 2.5 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao Q6K, 9LL Type1, Type3 700 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6Z4BB 2.5 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao Q6K, 9LL Type1, Type3 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao 8BS, 57N Type1, Type3 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 80U Type1.5_Back 697 - 985 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao TOV Type1.5_Back 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai YAA Type1.5_Back 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai N7K Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_niiai APEdist_aaai N7Q Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai N7Q Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai N7W Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N7W Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N7Z Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_niiai APEdist_aaai N7B Type1.5_Back 701 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai N7B Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai N78 Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai N78 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao N82 Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao N82 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_ooiai APEdist_aaao HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 700 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 699 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 816 Type1.5_Back 700 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai HYZ Type1.5_Back 702 - 1016 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai POX Type1.5_Back 702 - 1015 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 26X Type1.5_Back 700 - 1014 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 704 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 03P Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai W19 Type1.5_Back 701 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao FMM Type1.5_Back 702 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 2EI Type1.5_Back 699 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 26X Type1.5_Back 705 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 26X Type1.5_Back 702 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai A1H7N Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao A1IUK Type1.5_Back 702 - 986 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_iiiai APEdist_aaao A1IUK Type1.5_Back 702 - 985 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WAKC 2.4 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao TQA Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WXNC 1.76 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao UEJ Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WXND 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai UEJ Type1.5_Front 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao IXC Type1.5_Front 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_niiai APEdist_aaao VNS, 8RC Type1.5_Front, Type1 702 - 1002 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao 9LL Type3 702 - 985 0 None T790M,C797S,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1DC 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai NQ1, ANP Type3, ATPlike 702 - 1006 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6P1DD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai NQ1, ANP Type3, ATPlike 701 - 1008 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6XL4B 2.06 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai NQ1, Q6K Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPC 2.16 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXPE 2.16 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 703 - 1004 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, 8RC Type3, Type1 702 - 1003 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 701 - 1008 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai VNS, YY3 Type3, Type1 703 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHE 3.27 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VOY Type1.5_Back 709 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 6OP9A 2.501 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oiiai APEdist_aaai DB8 Type1 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBWA 4.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 708 - 991 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBWB 4.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 2R4BA 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 2R4BB 2.4 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBTB 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan FMM Type1.5_Back 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBTD 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan FMM Type1.5_Back 709 - 988 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8JQIB 4.1 Inactive DFGin‑BLBplus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 463 - 769 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8YKIA 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8YKIB 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQLB 2.8 Inactive DFGin‑BLBplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XZ7A 1.75 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1 458 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nioai APEdist_aaao LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDUA 1.737 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iiiai APEdist_aaao WIQ Type1.5_Back 460 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8KH9A 1.42 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao VVW Type1 454 - 752 0 None C477A,V550M,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus in-out none-none TYR APEdihe_nniai APEdist_aaai 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGR FGR_HUMAN 7UY0A 2.55 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr Homo sapiens
TYR FGR FGR_HUMAN 7UY0B 2.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr Homo sapiens
TYR HCK HCK_HUMAN 5ZJ6A 1.696 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1 248 - 518 0 None None Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 1QCFA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao PP1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS2A 2.609 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSB Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS5A 2.851 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS5B 2.851 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS7B 3.001 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan KS1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUDA 2.85 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SK8 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUDB 2.85 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SK8 Type1 81 - 524 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0GA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOU Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5ZJ6B 1.696 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1.5_Back 249 - 518 0 None None Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 9BYJA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VRYA 2.481 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VRYB 2.481 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS3A 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS3B 2.17 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS4A 2.747 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS4B 2.747 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS6A 2.373 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS6B 2.373 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUEA 3.04 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUEB 3.04 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H09A 1.945 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOO Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0BA 1.651 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOQ Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0EA 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOS Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0HA 1.72 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai OOV Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR ITK ITK_HUMAN 1SNXA 3.2 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 1SNXB 3.2 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3MJ2A 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao MJG Type1 357 - 615 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PPAA 2.67 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PPAB 2.67 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PPBA 2.82 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4PPBB 2.82 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4QD6B 2.45 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 1SM2A 2.3 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 1SNUA 2.5 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4HCTA 1.48 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 18R Type1 354 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4HCUA 1.43 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 13L Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4HCVA 1.48 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 13J Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 9NWXA 1.348 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1B66 Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3T9TA 1.65 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao IAQ Type1 356 - 618 0 None F435T,K596R Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M0YA 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao M0Y, M0Y Type1, Type3 356 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M14A 1.55 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QWS, QWS Type1, Type3 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M12A 2.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1YZ Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M13A 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E0 Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M15A 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QWS, ADP Type3, ATPlike 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M0ZA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao M0Z, M0Z Type3, Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR KDR VGFR2_HUMAN 3WZDA 1.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao LEV Type1 820 - 1167 0 None T940V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3B8RA 2.7 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 887 Type1 818 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3B8RB 2.7 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 887 Type1 821 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR LCK LCK_HUMAN 3MPMA 1.95 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_nnoai APEdist_aaao 5LK Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 4C3FA 1.72 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_nniai APEdist_aaao 7KW Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck Homo sapiens
TYR MERTK MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7DXLA 3.146 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nnoai APEdist_aaao E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7DXLB 3.146 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BPRA 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BPRB 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BPRC 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 3BPRD 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 4M3QB 2.718 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 577 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 4MHAA 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 580 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 5K0KA 2.545 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 5K0XA 2.231 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AVXA 2.44 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai S4K Type1.5_Front 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 3DKCA 1.52 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ATP ATPlike 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 2G15A 2.15 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1046 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 1R1WA 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AU3A 2.26 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao 3E8 Type1 1052 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AU3B 2.26 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nnoai APEdist_aaao 3E8 Type1 1056 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AU5A 2.72 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1067 - 1346 0 None F1200I Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AW1A 2.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai 3E8 Type1 1066 - 1345 0 None Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AW1B 2.14 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1064 - 1345 0 None Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4KNBA 2.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 1RU Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4KNBB 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 1RU Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4KNBC 2.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 1RU Type1 1060 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4KNBD 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 1RU Type1 1064 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4R1VA 1.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3E8 Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 2WD1A 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai ZZY Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4R1YA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 3EH Type1 1062 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3F66A 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai IHX Type1 1052 - 1349 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3F66B 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai IHX Type1 1062 - 1349 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B3QA 1.75 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SV5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B3TA 2.23 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai SVK Type1 1062 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B3VA 1.93 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SWB Type1 1057 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B3WA 2.02 Inactive DFGin‑BLBplus none-none out-in TYR APEdihe_iiiai APEdist_aaai SVH Type1 1067 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B3ZA 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SV8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B40A 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SWN Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B41A 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SWK Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B42A 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai SW8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B43A 1.87 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SW5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B43B 1.87 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SW5 Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7B44A 1.76 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan SVT Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 2WGJA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai VGH Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 2WKMA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai PFY Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3ZBXA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 6XE Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3ZC5A 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai W9Z Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3ZCLA 1.4 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5TF Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3ZXZA 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai KRW Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3ZZEA 1.87 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 6XP Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4AOIA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 4K0 Type1 1052 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4AP7A 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai F47 Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 6SDEA 2.49 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai V0L Type1 1068 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7Y4TA 2.16 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai I90 Type1 1063 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7Y4UA 2.26 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai I94 Type1 1061 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8GVJA 2.71 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai KGL Type1 1060 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8K78A 2.67 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai IYC Type1 1048 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 9IVBA 2.35 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1L3A Type1 1040 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 9IVBB 2.35 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1L3A Type1 1045 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3I5NA 2.0 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai B2D Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4DEGA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JJ Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4DEHA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JK Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4DEIA 2.05 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0JL Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4XMOA 1.75 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 46G Type1 1051 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4XYFA 1.85 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 44X Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5EYCA 1.8 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5SZ Type1 1053 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5EYDA 1.85 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5T1 Type1 1052 - 1348 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 2RFSA 2.2 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai AM8 Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3CCNA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai LKG Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3CD8A 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai L5G Type1 1054 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4GG5A 2.423 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai 0J3 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4GG7A 2.27 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 0J8 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5EOBA 1.75 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 5QQ Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5YA5A 1.89 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai 6TD Type1 1057 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5UABA 1.9 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84M Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5UADA 2.25 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84P Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 6UBWA 2.0 Inactive DFGin‑BLBplus out-out out-in TYR APEdihe_iiiai APEdist_aaai 84S Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3DKGA 1.91 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_nniai APEdist_aaai SX8 Type1 1050 - 1356 0 None Y1194F,Y1230L,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 1R0PA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao KSA Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HNIX 1.71 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HNIY 1.71 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnan APEdist_aaan 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HO6A 1.97 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 63K Type1 1063 - 1356 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3QTIA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3QT Type1 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3QTIB 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 3QT Type1 1058 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3DKFA 1.8 Inactive DFGin‑BLBplus out-none out-none TYR APEdihe_niiai APEdist_aaai SX8 Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3A4PA 2.54 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai DFQ Type1 1063 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HOAA 2.14 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 63K Type1 1065 - 1356 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HORA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao 63K Type1 1064 - 1356 0 None Y1194F,Y1234F,Y1235D,M1250T Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3U6HA 2.0 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 03X Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3U6IA 2.1 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 044 Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MST1R RON_HUMAN 3PLSA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 1060 - 1357 0 None M1254T Macrophage-stimulating protein receptor Homo sapiens
TYR MST1R RON_HUMAN 8ZKDA 2.05 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao ANP ATPlike 1060 - 1357 0 None None Macrophage-stimulating protein receptor Homo sapiens
TYR PTK6 PTK6_HUMAN 5D7VA 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5D7VB 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5D7VC 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5D7VD 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 6CZ2A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao No_ligand No_ligand 182 - 443 0 PTR342 None Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5H2UA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5H2UB 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5H2UC 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5H2UD 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 5DA3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 58V Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
TYR PTK6 PTK6_HUMAN 6CZ3A 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao FLJ Type1 182 - 443 0 None None Protein-tyrosine kinase 6 Homo sapiens
TYR SRC SRC_HUMAN 2SRCA 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ANP ATPlike 87 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 9IRLA 2.031 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao A1L20 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 8JN8A 1.902 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao JA6 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 8JN9A 2.724 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao UJ0 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 2H8HA 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao H8H Type1 88 - 532 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 4K11A 2.3 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 0J9 Type1 87 - 534 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 1KSWA 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao NBS Type1 87 - 536 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 7NG7A 1.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao UCW Type1.5_Back 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SYK KSYK_HUMAN 4FL3A 1.9 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 9 - 635 0 None Y348F,Y352F Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4FL2A 2.19 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iioai APEdist_aaao ANP ATPlike 9 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 3TUCA 2.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan FPW Type1.5_Front 358 - 633 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR TEK TIE2_HUMAN 3L8PA 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 0CE Type1 814 - 1121 0 None None Angiopoietin-1 receptor Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZSA 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZSB 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZSC 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZSD 3.23 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 115 - 446 0 None None Activated CDC42 kinase 1 Homo sapiens
OTHER TKUL E9B6S8_LEIMU 9GMPA 1.89 Inactive DFGin‑BLBplus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 647 - 921 0 None None Protein kinase domain-containing protein Leishmania mexicana
TKL LYS6 D3KTZ6_LOTJA 9GB9A 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9B 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9C 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9D 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 578 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK A0A811MC32_9POAL 8HOAA 1.676 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaooo APEdist_nnno ATP, HX2 ATPlike, Allosteric 90 - 387 0 None None non-specific serine/threonine protein kinase Miscanthus lutarioriparius
CMGC MAPK14 MK14_MOUSE 6Y7ZA 1.35 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nooo OG2, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y80A 1.24 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo OFZ, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y85A 1.58 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnoo OG8, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1YWRA 1.95 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo LI9 Type1 5 - 352 0 None T180A,Y182F Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 2GHLA 2.099 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno LIB Type1 5 - 352 0 None T180A,Y182F Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7PVUB 2.154 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 8DI Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y8HA 1.37 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4 Type1 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8ACMAAA 2.14 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOOA 1.95 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPA 2.049 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPD 2.049 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5O90A 2.49 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nooo SB4 Type1 5 - 353 0 None T185G Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7WA 1.39 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OFW Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7XA 1.45 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OFQ Type1, Allosteric 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y81A 1.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OG5 Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y82A 1.44 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo SB4, 308 Type1, Allosteric 6 - 360 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YCWA 1.34 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nooo SB4, OL8 Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOVA 1.31 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, LOT, LOW Type1, Allosteric, Allosteric 6 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SP9A 1.22 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno SB4, LOT, LOT Type1, Allosteric, Allosteric 5 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7YA 1.51 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo SB4, OFQ, LOT, LOT Type1, Allosteric, Allosteric, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SPLA 1.38 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo SB4, LOW, LOW, LOW Type1, Allosteric, Type1, Allosteric 6 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oioo IIM, 87B Type1, Type1 5 - 354 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3A 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 560 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3B 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4A 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31K, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5A 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi 31L, ADP, PEU Allosteric, ATPlike, Allosteric 562 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CA 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn BX7 Type1 2 - 651 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CB 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoio APEdist_nnno BX7 Type1 2 - 653 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR BTK BTK_MOUSE 6MNYB 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 4XI2A 2.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 214 - 657 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8S93A 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 1 - 659 0 None Q91A,I92A,I94A,I95A,K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8GMBA 3.4 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 214 - 659 0 None E298A,K300A,E301A,A384P,S386P,T387P,A388P,L390F,K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 6MNYA 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao JVP Type1.5_Back 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FD9A 1.7 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao XQQ Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FF0A 2.6 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 7GB Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJXA 2.86 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI1 Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME2A 3.38 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BKW Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME3A 3.05 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BJE Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJJA 2.03 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao A1BIZ Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJJB 2.03 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BIZ Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJRA 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BI0 Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJRB 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BI0 Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSA 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSB 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSC 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR SRC SRC_MOUSE 8XN8A 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 534 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
TYR SRC SRC_MOUSE 6F3FA 2.418 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 531 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
STE MAP2K1 MP2K1_RABIT 7JUQC 3.22 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP ATPlike 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUWC 2.88 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 2Y4IC 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP ATPlike 37 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JURC 2.82 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type1 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUTC 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3EW ATPlike, Type3 41 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUUC 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 43 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUVC 3.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, VKG ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUXC 3.34 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUYC 3.096 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUZC 3.21 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3EW ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JV0C 3.63 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JV1C 3.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, VKG ATPlike, Type3 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 5KKRC 3.509 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUSC 2.99 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo VKD, ANP Type3, ATPlike 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
CAMK CDPK1 Q9BJF5_TOXGO 3MA6B 2.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo DXR Type1 46 - 312 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK3 Q3HNM6_TOXGO 3DXNA 2.17 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 72 - 340 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii
CAMK CDPK3 Q3HNM6_TOXGO 3HZTA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno J60 Type1 73 - 533 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays

All / BLBplus / All

Total number of chains: 101
Active chains: 0
Total number of genes: 17
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 101 100.0% 4Y95A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TYR BTK Q3ZC95_BOVIN 4Y95A 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95D 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y93A 1.695 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746 Type1 1 - 658 0 None L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95B 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746, PE4 Type1, Allosteric 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR BTK Q3ZC95_BOVIN 4Y95C 1.599 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 746, PE4 Type1, Allosteric 395 - 659 0 None L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase Bos taurus
TYR LET23 LET23_CAEEL 5WNOA 2.386 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nooai APEdist_aaao ANP ATPlike 876 - 1190 0 None None Receptor tyrosine-protein kinase let-23 Caenorhabditis elegans
CAMK CDPK1 A3FQ16_CRYPI 3IGOA 2.25 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 4Y5QA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo AMP ATPlike 70 - 537 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9D8SA 2.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AMP ATPlike 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 3MWUA 1.98 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo BK3 Type1 70 - 536 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 3NCGA 2.49 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo BK1 Type1 70 - 533 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9MI4A 2.94 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo A1BLB Type1 70 - 535 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK1 A3FQ16_CRYPI 9MI5A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BLC Type1 70 - 532 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
STE DSOR1 DSOR1_DROME 8BW9C 3.32 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 81 - 384 0 None None Dual specificity mitogen-activated protein kinase kinase dSOR1 Drosophila melanogaster
TYR SRC SRC_CHICK 5BMMA 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5BMMB 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 2PTKA 2.35 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 83 - 528 0 PTR527 None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBKA 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao 4B7 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
OTHER TKUL E9B6S8_LEIMU 9GMPA 1.89 Inactive DFGin‑BLBplus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 647 - 921 0 None None Protein kinase domain-containing protein Leishmania mexicana
TKL LYS6 D3KTZ6_LOTJA 9GB9A 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9B 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9C 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9D 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 578 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK A0A811MC32_9POAL 8HOAA 1.676 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaooo APEdist_nnno ATP, HX2 ATPlike, Allosteric 90 - 387 0 None None non-specific serine/threonine protein kinase Miscanthus lutarioriparius
CMGC MAPK14 MK14_MOUSE 6Y7ZA 1.35 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nooo OG2, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y80A 1.24 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo OFZ, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y85A 1.58 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnoo OG8, SB4 Allosteric, Type1 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1YWRA 1.95 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo LI9 Type1 5 - 352 0 None T180A,Y182F Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 2GHLA 2.099 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno LIB Type1 5 - 352 0 None T180A,Y182F Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7PVUB 2.154 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 8DI Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y8HA 1.37 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4 Type1 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8ACMAAA 2.14 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOOA 1.95 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPA 2.049 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPD 2.049 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5O90A 2.49 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoni APEdist_nooo SB4 Type1 5 - 353 0 None T185G Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7WA 1.39 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OFW Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7XA 1.45 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OFQ Type1, Allosteric 5 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y81A 1.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, OG5 Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y82A 1.44 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo SB4, 308 Type1, Allosteric 6 - 360 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YCWA 1.34 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nooo SB4, OL8 Type1, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOVA 1.31 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo SB4, LOT, LOW Type1, Allosteric, Allosteric 6 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SP9A 1.22 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno SB4, LOT, LOT Type1, Allosteric, Allosteric 5 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y7YA 1.51 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo SB4, OFQ, LOT, LOT Type1, Allosteric, Allosteric, Allosteric 6 - 359 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SPLA 1.38 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaioi APEdist_nooo SB4, LOW, LOW, LOW Type1, Allosteric, Type1, Allosteric 6 - 359 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaooi APEdist_oioo IIM, 87B Type1, Type1 5 - 354 0 None C162S Mitogen-activated protein kinase 14 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3A 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 560 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3B 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4A 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31K, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5A 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi 31L, ADP, PEU Allosteric, ATPlike, Allosteric 562 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CA 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn BX7 Type1 2 - 651 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CB 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoio APEdist_nnno BX7 Type1 2 - 653 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR BTK BTK_MOUSE 6MNYB 2.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 4XI2A 2.6 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 214 - 657 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8S93A 2.1 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 1 - 659 0 None Q91A,I92A,I94A,I95A,K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8GMBA 3.4 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 9AJ Type1 214 - 659 0 None E298A,K300A,E301A,A384P,S386P,T387P,A388P,L390F,K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 6MNYA 2.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao JVP Type1.5_Back 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FD9A 1.7 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao XQQ Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FF0A 2.6 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao 7GB Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJXA 2.86 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI1 Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME2A 3.38 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BKW Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME3A 3.05 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BJE Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJJA 2.03 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao A1BIZ Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJJB 2.03 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BIZ Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJRA 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BI0 Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJRB 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iooai APEdist_aaao A1BI0 Type1.5_Front 394 - 659 0 None L390G,Y551E,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSA 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSB 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJSC 2.26 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao A1BI0 Type1.5_Front 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR SRC SRC_MOUSE 8XN8A 1.95 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 534 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
TYR SRC SRC_MOUSE 6F3FA 2.418 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 85 - 531 0 PTR529 None Proto-oncogene tyrosine-protein kinase Src Mus musculus
STE MAP2K1 MP2K1_RABIT 7JUQC 3.22 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ADP ATPlike 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUWC 2.88 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP ATPlike 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 2Y4IC 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ATP ATPlike 37 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JURC 2.82 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type1 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUTC 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3EW ATPlike, Type3 41 - 380 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUUC 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 43 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUVC 3.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, VKG ATPlike, Type3 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUXC 3.34 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, QOM ATPlike, Type3 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUYC 3.096 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, EUI ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUZC 3.21 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 3EW ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JV0C 3.63 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, 4BM ATPlike, Type3 40 - 382 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JV1C 3.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo ANP, VKG ATPlike, Type3 40 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 5KKRC 3.509 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
STE MAP2K1 MP2K1_RABIT 7JUSC 2.99 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo VKD, ANP Type3, ATPlike 41 - 381 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus
CAMK CDPK1 Q9BJF5_TOXGO 3MA6B 2.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo DXR Type1 46 - 312 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK CDPK3 Q3HNM6_TOXGO 3DXNA 2.17 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 72 - 340 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii
CAMK CDPK3 Q3HNM6_TOXGO 3HZTA 2.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno J60 Type1 73 - 533 0 None None Calcium-dependent protein kinase 1 Toxoplasma gondii
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays