TKL_IRAK3 (Interleukin-1 receptor-associated kinase 3)

Total number of chains: 4
Active chains: 0
Uniprot: IRAK3_HUMAN
Kinase Domain Residues: 160 - 445
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6RUUA
None None 1 25.0% 6RUUC

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3
6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3
6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3
6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3

TKL_IRAK3 (Interleukin-1 receptor-associated kinase 3)

Total number of chains: 4
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 6RUUA
None None 1 25.0% 6RUUC

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
IRAK3_HUMAN 6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
IRAK3_HUMAN 6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
IRAK3_HUMAN 6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens

TKL_IRAK3 (Interleukin-1 receptor-associated kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism