STE_TNIK (TRAF2 and NCK-interacting protein kinase)

Total number of chains: 27
Active chains: 10
Uniprot: TNIK_HUMAN
Kinase Domain Residues: 25 - 289
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 18 66.7% AF-Q9UKE5-K1A
DFGin BLBplus 6 22.2% 5D7AA
DFGinter None 2 7.4% 8X88A
DFGin None 1 3.7% 2X7FE
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
AF-Q9UKE5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 297 0 None None TRAF2 and NCK-interacting protein kinase
AF-Q9UKE5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 297 0 None None TRAF2 and NCK-interacting protein kinase
7XZQA 2.09 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
8ZMLB 2.489 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1 10 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
6RA5A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JWE Type1 12 - 309 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
6RA7A 1.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JWK Type1 13 - 314 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
8WM0A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 12 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
8ZMLA 2.489 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1.5_Back 11 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
7XZRA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP Type1.5_Front 12 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
5AX9A 2.4 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 4KT Type1 12 - 307 0 None None TRAF2 and NCK-interacting protein kinase
5AX9B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 4KT Type1 13 - 307 0 None None TRAF2 and NCK-interacting protein kinase
5AX9C 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno 4KT Type1 12 - 309 0 None None TRAF2 and NCK-interacting protein kinase
2X7FA 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaini APEdist_nnno 824 Type1 15 - 313 0 None None TRAF2 and NCK-interacting protein kinase
2X7FB 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnno 824 Type1 13 - 313 0 None None TRAF2 and NCK-interacting protein kinase
2X7FC 2.8 Inactive DFGin‑BLAminus in-none out-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 313 0 None None TRAF2 and NCK-interacting protein kinase
5CWZA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
5CWZB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
5CWZC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 15 - 308 0 None None TRAF2 and NCK-interacting protein kinase
5D7AA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 310 0 None None TRAF2 and NCK-interacting protein kinase
5D7AB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase
5D7AC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 58C Type1 13 - 310 0 None None TRAF2 and NCK-interacting protein kinase
2X7FE 2.8 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 309 0 None None TRAF2 and NCK-interacting protein kinase
8X88A 2.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 15 - 311 0 None None TRAF2 and NCK-interacting protein kinase
8X88B 2.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 17 - 311 0 None None TRAF2 and NCK-interacting protein kinase
6RA5B 2.9 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
2X7FD 2.8 None DFGin‑BLAminus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase

STE_TNIK (TRAF2 and NCK-interacting protein kinase)

Total number of chains: 27
Active chains: 10
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 18 66.7% AF-Q9UKE5-K1A
DFGin BLBplus 6 22.2% 5D7AA
DFGinter None 2 7.4% 8X88A
DFGin None 1 3.7% 2X7FE
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TNIK_HUMAN 7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN AF-Q9UKE5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 297 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN AF-Q9UKE5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 297 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 7XZQA 2.09 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 8ZMLB 2.489 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1 10 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 6RA5A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JWE Type1 12 - 309 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 6RA7A 1.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JWK Type1 13 - 314 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 8WM0A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 12 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 8ZMLA 2.489 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1.5_Back 11 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 7XZRA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP Type1.5_Front 12 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5AX9A 2.4 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 4KT Type1 12 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5AX9B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 4KT Type1 13 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5AX9C 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno 4KT Type1 12 - 309 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 2X7FA 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaini APEdist_nnno 824 Type1 15 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 2X7FB 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnno 824 Type1 13 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 2X7FC 2.8 Inactive DFGin‑BLAminus in-none out-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5CWZA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5CWZB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5CWZC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 15 - 308 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5D7AA 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 310 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5D7AB 2.9 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaioi APEdist_oioo 58C Type1 11 - 307 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 5D7AC 2.9 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 58C Type1 13 - 310 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 2X7FE 2.8 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 309 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 8X88A 2.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 15 - 311 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 8X88B 2.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 17 - 311 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 6RA5B 2.9 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TNIK_HUMAN 2X7FD 2.8 None DFGin‑BLAminus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens

STE_TNIK (TRAF2 and NCK-interacting protein kinase)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism