PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 4UX9A
DFGin None 1 25.0% 4UX9B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9B 2.34 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 362 0 None None Mitogen-activated protein kinase 8

PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 4UX9A
DFGin None 1 25.0% 4UX9B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9B 2.34 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens

PDB: 4UX9 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism