Activity: None (unassigned)

Total number of chains: 362
Active chains: 0
Total number of genes: 65
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 362 100.0% 4CT1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC PDPK1 PDPK1_HUMAN 4CT1A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP, 31S ATPlike, Allosteric 76 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QD0A 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 3Q4 Type1.5_Front 73 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QD4A 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 3Q6 Type1.5_Front 71 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1
AGC PRKCI KPCI_HUMAN 9EJMB 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 6ILZC 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 6ILZE 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 255 - 587 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 6ILZG 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKG1 KGP1_HUMAN 6BDLB 1.96 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S26B 2.744 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 86K Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNEB 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK2 ROCK2_HUMAN 7JOVB 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFS Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7JOVD 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFS Type1 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7JOVE 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_innn VFS Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7JNTB 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFA Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7JNTD 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFA Type1 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7JNTE 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn VFA Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6NC 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6NE 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6NH 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6OC 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YK Type1.5_Front 22 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 7P6OH 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YK Type1.5_Front 24 - 417 0 None None Rho-associated protein kinase 2
CAMK CAMK1 KCC1A_HUMAN 4FG7A 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ATP ATPlike 9 - 277 0 None None Calcium/calmodulin-dependent protein kinase type 1
CAMK CAMK2B KCC2B_HUMAN 3BHHC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 300 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta
CAMK CAMK2B KCC2B_HUMAN 3BHHD 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 301 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta
CAMK CAMK2B KCC2B_HUMAN 3BHHA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 5CP Type1 11 - 301 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta
CAMK CAMKK2 KKCC2_HUMAN 6BRCA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii E5J Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2
CAMK DAPK1 DAPK1_HUMAN 3ZXTB 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTC 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 5 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 3ZXTD 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BC 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BD 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BE 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BF 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BG 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BH 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BI 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BJ 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BK 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BL 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3G 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPJ 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 328 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XX1A 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 364 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R2YA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3R30A 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn CD2 Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 42 - 346 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYC 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 359 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 347 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 349 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3C 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 41 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3D 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 46 - 342 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3E 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3F 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3H 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3I 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 45 - 356 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3J 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 348 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3K 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3L 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 42 - 348 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPA 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPB 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPC 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPD 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPE 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPF 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPG 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPH 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPI 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPK 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKA 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKB 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKC 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKD 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKE 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKF 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKG 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKH 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKI 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKJ 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKK 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKL 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KA0A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK3 Type1 47 - 364 0 None T222E MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKB 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKC 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 41 - 357 0 None None MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3KGAA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LX9 Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3M2WA 2.41 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn L8I Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 3M42A 2.68 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn HGF Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 6T8XB 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 6T8XC 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 44 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2
CAMK MAPKAPK3 MAPK3_HUMAN 3R1NA 2.09 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 33 - 348 0 None None MAP kinase-activated protein kinase 3
CAMK MAPKAPK3 MAPK3_HUMAN 3SHEA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn I85 Type1 33 - 348 0 None None MAP kinase-activated protein kinase 3
CAMK MAPKAPK3 MAPK3_HUMAN 3FHRA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3
CAMK MAPKAPK3 MAPK3_HUMAN 3FXWA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn F10 Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3
CAMK MAPKAPK3 MAPK3_HUMAN 7NRBA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3
CAMK MELK MELK_HUMAN 5IH8A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BJ Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 5IH9A 1.79 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BF Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 5IHAA 1.96 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BE Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 6GVXA 2.24 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4BKYA 1.83 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 82B Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2TB 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2TC 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2TD 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2VA 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2VC 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2VD 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WC 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPD 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PB 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PC 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PD 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPC 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK PIM2 PIM2_HUMAN 2IWIA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii HB1 Type1 32 - 288 0 None None Serine/threonine-protein kinase pim-2
CAMK PIM2 PIM2_HUMAN 2IWIB 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii HB1 Type1 22 - 287 0 None None Serine/threonine-protein kinase pim-2
CAMK PIM2 PIM2_HUMAN 4X7QA 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 3YR Type1 32 - 287 0 None None Serine/threonine-protein kinase pim-2
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5B 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN6A 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN6B 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP4A 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP4B 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP5A 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP5B 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP7A 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 415 - 725 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP7B 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 416 - 728 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP8A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP8B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 727 0 None None Ribosomal protein S6 kinase alpha-5
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP6A 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn SUU, OXM, OXM Type1, Allosteric, Allosteric 416 - 707 0 None None Ribosomal protein S6 kinase alpha-5
CAMK STK17B ST17B_HUMAN 7Q7CA 2.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B
CK1 CSNK1A1 KC1A_HUMAN 8G66F 3.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 10 - 303 0 None None Casein kinase I isoform alpha
CK1 CSNK1D KC1D_HUMAN 6RU6B 2.05 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 3UYTD 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 0CK Type1 4 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 5OKTB 2.13 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 9XK Type1 4 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7NZYB 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii UX2 Type1 2 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 4KB8A 1.95 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 1QN Type1 3 - 293 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 4KBAA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 1QM Type1 3 - 293 0 None None Casein kinase I isoform delta
CK1 CSNK1G1 KC1G1_HUMAN 2CMWA 1.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini OLP, OLP, OLP Type1, Allosteric, Allosteric 44 - 339 0 None None Casein kinase I isoform gamma-1
CK1 CSNK1G2 KC1G2_HUMAN 2C47C 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID Type1 46 - 337 0 None None Casein kinase I isoform gamma-2
CK1 TTBK1 TTBK1_HUMAN 4NFMA 2.12 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 314 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7JXYB 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1
CMGC CDK2 CDK2_HUMAN 3EIDC 3.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_inni No_ligand No_ligand 1 - 296 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3EIDA 3.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii PO5 Type1 1 - 297 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9GOPA 2.158 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1IOI Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDKL1 CDKL1_HUMAN 4AGUA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 2 - 291 0 None T159D,Y161E Cyclin-dependent kinase-like 1
CMGC CDKL1 CDKL1_HUMAN 4AGUB 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 3 - 292 0 None T159D,Y161E Cyclin-dependent kinase-like 1
CMGC CDKL1 CDKL1_HUMAN 4AGUC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 2 - 291 0 None T159D,Y161E Cyclin-dependent kinase-like 1
CMGC CLK1 CLK1_HUMAN 6Q8PA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_iiin HQB Type1 148 - 482 0 None None Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6Q8PC 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_iiin HQB Type1 148 - 483 0 None None Dual specificity protein kinase CLK1
CMGC DYRK1A DYR1A_HUMAN 6S11B 2.445 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii KQE Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7Z5NH 2.77 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_niii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC GSK3B GSK3B_HUMAN 4DITA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_iinn 0KD Type1 35 - 387 0 PTR216 None Glycogen synthase kinase-3 beta
CMGC MAPK1 MK01_HUMAN 4FV4A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii EK7 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4FV5A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni EK9 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4FV6A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E57 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4FV8A 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii E63 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4FV9A 2.11 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E71 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BUEA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V8 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BUIA 2.12 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V9 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BUJA 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BVDA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VF Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BVEA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VG Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5BVFA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 4VJ Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 3I5ZA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii Z48 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 3I60A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E86 Type1 8 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 6OPIA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn N0V Type1.5_Front 10 - 356 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA8A 1.79 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9BA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9BC 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9CA 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA6A 1.44 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase
OTHER ERN1 ERN1_HUMAN 4YZCA 2.494 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZCB 2.494 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3KA 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii SJS Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER GAK GAK_HUMAN 4Y8DA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4Y8DB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER WNK1 WNK1_HUMAN 5WDYA 2.458 None DFGin‑BLAminus DFGAsp-rot-in na-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP, A6S ATPlike, Type3 208 - 481 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1
STE MAP2K7 MP2K7_HUMAN 5Z1DA 2.28 None DFGin‑BLAminus DFGAsp-rot-in na-na none-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG3A 2.05 None DFGin‑BLAminus DFGAsp-rot-in na-na in-none nonTYR APEdihe_aannn APEdist_nnnn 6HF Type1 103 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP3K14 M3K14_HUMAN 4G3DD 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii No_ligand No_ligand 338 - 657 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 4G3DE 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanin APEdist_nnii No_ligand No_ligand 332 - 663 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K5 M3K5_HUMAN 6OYTA 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn NJV Type1 667 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYTC 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn NJV Type1 671 - 938 0 None None Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6OYTD 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni NJV Type1 667 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 5UP3B 2.95 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 8GS Type1 671 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6E2NB 2.098 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii KK8 Type1 670 - 939 0 TPO838 None Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 7MU6B 2.165 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1AWT Type1 671 - 940 0 None None Mitogen-activated protein kinase kinase kinase 5
STE MAP4K1 M4K1_HUMAN 6NFZA 2.966 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii B49 Type1 7 - 292 0 TPO165,SEP171 None Mitogen-activated protein kinase kinase kinase kinase 1
STE PAK1 PAK1_HUMAN 4DAWA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 0H2 Type1 249 - 542 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 2HY81 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 1ST Type1 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1
STE STK4 STK4_HUMAN 6YATB 2.58 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii OJ5 Type1 29 - 307 0 TPO177,TPO183 None Serine/threonine-protein kinase 4
STE TNIK TNIK_HUMAN 6RA5B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 2X7FD 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase
TKL ACVR1 ACVR1_HUMAN 8R7GC 2.09 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii YEE Type1 206 - 498 0 None Q207D Activin receptor type-1
TKL BMPR2 BMPR2_HUMAN 6UNPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2
TKL BRAF BRAF_HUMAN 4MNFA 2.802 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL IRAK4 IRAK4_HUMAN 2OICC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aaiii APEdist_nnni STU Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K72B 2.22 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6QY Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7GB 2.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6R0 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYB 2.19 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGDA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U9AA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL TGFBR1 TGFR1_HUMAN 3HMMA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 855 Type1 201 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3TZMA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii 085 Type1 200 - 496 0 None None TGF-beta receptor type-1
TKL TGFBR2 TGFR2_HUMAN 5QINA 1.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii J2V Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TNNI3K TNI3K_HUMAN 4YFFA 3.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFFB 3.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 6B5JB 2.97 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TYR CSK CSK_HUMAN 3D7UA 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN 3D7UC 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK
TYR EGFR EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JX4A 2.531 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 696 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7VRAA 2.41 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa I0A Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7VREA 2.507 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 7VH Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9KLWA 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L53 Type1 696 - 1019 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2J5FA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa DJK Type1 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa QP1 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8G63A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa YXT Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DM8A 2.13 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa A1A6K Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NGPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1BX7 Type1 698 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NHWA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYD Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NISA 2.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYK Type1 696 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NJ7A 2.53 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYL Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NJNA 2.24 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYS Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VO7 Type1 697 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9OS6A 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1CEA Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9H46A 3.163 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1ISA Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ZRT Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZAUA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7B85A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S9BA 3.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1H Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S9CA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1K Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ4A 2.78 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QW Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ7A 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3R1 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QS Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8KA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YV Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8MA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YW Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8NA 2.401 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YX Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CALA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4Z8 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CANA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZB Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAOA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4ZG Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZH Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM7A 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q4 Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCXA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60B Type1 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCZA 2.62 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60E Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITTA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa AEE Type1 697 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X26A 2.951 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XO Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XR Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XU Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XDLA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8JC Type1 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD 3.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L8T Type1 696 - 987 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa FZP Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 3QY Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZJ Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZQ Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZR Type1.5_Back 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60D Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 63N Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 5I9VA 1.458 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa AGS ATPlike 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 1MQBB 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 602 - 883 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAB 1.75 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ACP ATPlike 590 - 965 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0A 1.948 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa A5B Type1 604 - 889 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKAA 1.377 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa 91H Type1 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHC 1.379 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa DXK Type1 600 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 2QOQA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 595 - 906 0 PTR701 None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2GSFA 1.77 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None A608T Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOKA 1.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F,S768A Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK3A 1.898 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa L87 Type1 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4P5QA 1.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa Q0B Type1 609 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4TWOA 2.047 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37W Type1 609 - 906 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4G2FA 1.699 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa C07 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK2A 2.195 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L66 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK4A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L90 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA7 EPHA7_HUMAN 7EEDA 3.05 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None D751H Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 2REIA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None None Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 7EECA 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None G656R Ephrin type-A receptor 7
TYR EPHA8 EPHA8_HUMAN 3KULA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 627 - 900 0 None None Ephrin type-A receptor 8
TYR EPHB1 EPHB1_HUMAN 3ZFXB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXC 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 614 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXF 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 612 - 893 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXG 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJAA 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 7O3 Type1.5_Back 609 - 892 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB4 EPHB4_HUMAN 6FNLA 1.269 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 3ZEWA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STU Type1 609 - 888 0 PTR774 None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 3ZEWB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none none-none TYR APEdihe_nniai APEdist_aaaa STU Type1 609 - 887 0 PTR774 None Ephrin type-B receptor 4
TYR FES FES_HUMAN 4E93A 1.84 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GUI Type1 448 - 822 0 None None Tyrosine-protein kinase Fes/Fps
TYR IGF1R IGF1R_HUMAN 3LVPD 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR ITK ITK_HUMAN 3QGYB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L7O Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR JAK2-2 JAK2_HUMAN 4D1SA 1.66 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa BJG Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5USYA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5USYB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK3-2 JAK3_HUMAN 6HZVA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVB 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1099 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVC 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVD 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86A 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86B 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 816 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86C 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86D 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKD 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9T6 Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6B 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa VFC Type1 813 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6C 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6D 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPB 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPC 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPD 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVD 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5VO6A 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9J4 Type1 815 - 1099 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6NY4A 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa Z3A Type1 815 - 1099 0 None C811S,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4V0GB 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 816 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4V0GA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 817 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16C 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16D 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QPSA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37Q Type1 814 - 1100 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QPSC 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 37Q Type1 814 - 1102 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLAA 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLAB 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 9R5ZA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 822 - 1101 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 9R5ZB 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 816 - 1101 0 None None Tyrosine-protein kinase JAK3
TYR KIT KIT_HUMAN 1PKGB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ADP ATPlike 566 - 929 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQBA 1.87 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9XO Type1 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQEB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9WU Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR PTK2 FAK1_HUMAN 6YVYB 1.918 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa P1E Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR SRC SRC_HUMAN 6E6EH 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXOA 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXOB 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6ATEA 2.402 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 6H3 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SYK KSYK_HUMAN 1XBBA 1.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STI Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQHB 2.26 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 057 Type1 363 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQSA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 585 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FYNA 2.318 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FZ6A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0RA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B4 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0SA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B5 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0TA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1B6 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5T68A 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5T68B 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UB 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8OU Type1 363 - 629 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3VF8A 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 0JE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3VF9A 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 477 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCRA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCUA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR TNK2 ACK1_HUMAN 1U4DA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DBQ Type1 117 - 389 0 None None Activated CDC42 kinase 1
TYR TYK2-2 TYK2_HUMAN 7UYSA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa OVC Type1 890 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 7UYUA 2.05 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa OV0 Type1 889 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6AAMA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9T6 Type1 888 - 1178 0 None C936A,Q969A,E971A,K972A,D1023N,I1114L,C1142A Non-receptor tyrosine-protein kinase TYK2

Activity: None (unassigned)

Total number of chains: 412
Active chains: 0
Total number of genes: 76
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 412 100.0% 5NTJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL FERONIA FERON_ARATH 9UBIB 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni OT5 Type1 521 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOD 2.502 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC PRKACA KAPCA_BOVIN 9DW8G 3.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 329 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_CRIGR 6EH2A 1.76 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5NTJA 1.56 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERUA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERVA 2.06 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y2OA 2.01 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii O72 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
TYR SRC SRC_CHICK 2OIQB 2.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3EL8B 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6HVEA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GUW Type1 256 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F6XA 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa IHH Type1 255 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F6XD 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa IHH Type1 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4O2PB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 11V Type1 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5XP7B 2.012 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 8C6 Type1 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4MCVA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 29K Type1 256 - 533 0 None T338G Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC PDPK1 PDPK1_HUMAN 4CT1A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP, 31S ATPlike, Allosteric 76 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3QD0A 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 3Q4 Type1.5_Front 73 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3QD4A 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 3Q6 Type1.5_Front 71 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PRKCI KPCI_HUMAN 9EJMB 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 6ILZC 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 6ILZE 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 255 - 587 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 6ILZG 3.261 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BDLB 1.96 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 7S26B 2.744 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 86K Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNEB 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JOVB 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFS Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JOVD 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFS Type1 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JOVE 2.586 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_innn VFS Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JNTB 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFA Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JNTD 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn VFA Type1 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7JNTE 2.214 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn VFA Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7P6NC 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7P6NE 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7P6NH 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YS Type1 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7P6OC 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YK Type1.5_Front 22 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 7P6OH 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 5YK Type1.5_Front 24 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
CAMK CAMK1 KCC1A_HUMAN 4FG7A 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ATP ATPlike 9 - 277 0 None None Calcium/calmodulin-dependent protein kinase type 1 Homo sapiens
CAMK CAMK2B KCC2B_HUMAN 3BHHC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 300 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta Homo sapiens
CAMK CAMK2B KCC2B_HUMAN 3BHHD 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 301 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta Homo sapiens
CAMK CAMK2B KCC2B_HUMAN 3BHHA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 5CP Type1 11 - 301 0 None None Calcium/calmodulin-dependent protein kinase type II subunit beta Homo sapiens
CAMK CAMKK2 KKCC2_HUMAN 6BRCA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii E5J Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTB 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTC 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 5 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTD 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BC 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BD 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BE 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BF 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BG 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BH 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BI 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BJ 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BK 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BL 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3G 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 43 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPJ 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 328 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XX1A 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 364 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2BB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R2YA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3R30A 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn CD2 Type1 46 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 42 - 346 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B18 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2PZYC 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 359 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 349 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3C 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 41 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3D 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 46 - 342 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3E 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3F 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3H 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3I 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 45 - 356 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3J 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 43 - 348 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3K 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KC3L 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK2 Type1 42 - 348 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPA 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPB 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPC 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPD 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPE 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPF 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPG 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPH 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 347 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPI 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 45 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 2JBPK 3.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 47 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKA 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKB 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKC 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKD 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKE 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKF 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKG 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKH 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKI 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKJ 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKK 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3GOKL 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 46 - 350 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KA0A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MK3 Type1 47 - 364 0 None T222E MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 42 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKB 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 44 - 345 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 1NXKC 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 41 - 357 0 None None MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3KGAA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LX9 Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3M2WA 2.41 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn L8I Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 3M42A 2.68 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn HGF Type1 47 - 364 0 None P237G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 6T8XB 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 45 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 6T8XC 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn B97, MW8 Type1, Allosteric 44 - 329 0 None T222E,T334E MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK3 MAPK3_HUMAN 3R1NA 2.09 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 05B Type1 33 - 348 0 None None MAP kinase-activated protein kinase 3 Homo sapiens
CAMK MAPKAPK3 MAPK3_HUMAN 3SHEA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn I85 Type1 33 - 348 0 None None MAP kinase-activated protein kinase 3 Homo sapiens
CAMK MAPKAPK3 MAPK3_HUMAN 3FHRA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3 Homo sapiens
CAMK MAPKAPK3 MAPK3_HUMAN 3FXWA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn F10 Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3 Homo sapiens
CAMK MAPKAPK3 MAPK3_HUMAN 7NRBA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn P4O Type1 33 - 349 0 None None MAP kinase-activated protein kinase 3 Homo sapiens
CAMK MELK MELK_HUMAN 5IH8A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BJ Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 5IH9A 1.79 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BF Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 5IHAA 1.96 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BE Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 6GVXA 2.24 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4BKYA 1.83 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 82B Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2TB 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2TC 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2TD 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2VA 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2VC 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2VD 2.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2WC 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPD 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PB 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PC 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PD 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPC 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK PIM2 PIM2_HUMAN 2IWIA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii HB1 Type1 32 - 288 0 None None Serine/threonine-protein kinase pim-2 Homo sapiens
CAMK PIM2 PIM2_HUMAN 2IWIB 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii HB1 Type1 22 - 287 0 None None Serine/threonine-protein kinase pim-2 Homo sapiens
CAMK PIM2 PIM2_HUMAN 4X7QA 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 3YR Type1 32 - 287 0 None None Serine/threonine-protein kinase pim-2 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN5B 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN6A 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 3KN6B 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 415 - 729 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP4A 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP4B 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1K Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP5A 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP5B 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O1R Type1 415 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP7A 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 415 - 725 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP7B 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1LE Type1 416 - 728 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP8A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 723 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP8B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn O10 Type1 415 - 727 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK RPS6KA5-2 KS6A5_HUMAN 7UP6A 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn SUU, OXM, OXM Type1, Allosteric, Allosteric 416 - 707 0 None None Ribosomal protein S6 kinase alpha-5 Homo sapiens
CAMK STK17B ST17B_HUMAN 7Q7CA 2.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 25 - 297 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CK1 CSNK1A1 KC1A_HUMAN 8G66F 3.45 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 10 - 303 0 None None Casein kinase I isoform alpha Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU6B 2.05 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 3UYTD 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 0CK Type1 4 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 5OKTB 2.13 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 9XK Type1 4 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7NZYB 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii UX2 Type1 2 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 4KB8A 1.95 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 1QN Type1 3 - 293 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 4KBAA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 1QM Type1 3 - 293 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1G1 KC1G1_HUMAN 2CMWA 1.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini OLP, OLP, OLP Type1, Allosteric, Allosteric 44 - 339 0 None None Casein kinase I isoform gamma-1 Homo sapiens
CK1 CSNK1G2 KC1G2_HUMAN 2C47C 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID Type1 46 - 337 0 None None Casein kinase I isoform gamma-2 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4NFMA 2.12 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 314 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7JXYB 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3EIDC 3.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_inni No_ligand No_ligand 1 - 296 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3EIDA 3.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii PO5 Type1 1 - 297 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9GOPA 2.158 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1IOI Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDKL1 CDKL1_HUMAN 4AGUA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 2 - 291 0 None T159D,Y161E Cyclin-dependent kinase-like 1 Homo sapiens
CMGC CDKL1 CDKL1_HUMAN 4AGUB 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 3 - 292 0 None T159D,Y161E Cyclin-dependent kinase-like 1 Homo sapiens
CMGC CDKL1 CDKL1_HUMAN 4AGUC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn D15 Type1 2 - 291 0 None T159D,Y161E Cyclin-dependent kinase-like 1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6Q8PA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_iiin HQB Type1 148 - 482 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6Q8PC 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_iiin HQB Type1 148 - 483 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 6S11B 2.445 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii KQE Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 7Z5NH 2.77 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_niii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4DITA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_iinn 0KD Type1 35 - 387 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FV4A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii EK7 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FV5A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni EK9 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FV6A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E57 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FV8A 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii E63 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 4FV9A 2.11 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E71 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BUEA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V8 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BUIA 2.12 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V9 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BUJA 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BVDA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VF Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BVEA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VG Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5BVFA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 4VJ Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 3I5ZA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii Z48 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 3I60A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E86 Type1 8 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 6OPIA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn N0V Type1.5_Front 10 - 356 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA8A 1.79 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9BA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9BC 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9CA 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA6A 1.44 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZCA 2.494 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZCB 2.494 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3KA 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii SJS Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER GAK GAK_HUMAN 4Y8DA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4Y8DB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5WDYA 2.458 None DFGin‑BLAminus DFGAsp-rot-in na-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP, A6S ATPlike, Type3 208 - 481 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 5Z1DA 2.28 None DFGin‑BLAminus DFGAsp-rot-in na-na none-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6YG3A 2.05 None DFGin‑BLAminus DFGAsp-rot-in na-na in-none nonTYR APEdihe_aannn APEdist_nnnn 6HF Type1 103 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4G3DD 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii No_ligand No_ligand 338 - 657 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4G3DE 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanin APEdist_nnii No_ligand No_ligand 332 - 663 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYTA 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn NJV Type1 667 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYTC 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn NJV Type1 671 - 938 0 None None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6OYTD 2.824 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni NJV Type1 667 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 5UP3B 2.95 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 8GS Type1 671 - 939 0 None None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 6E2NB 2.098 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii KK8 Type1 670 - 939 0 TPO838 None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP3K5 M3K5_HUMAN 7MU6B 2.165 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1AWT Type1 671 - 940 0 None None Mitogen-activated protein kinase kinase kinase 5 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6NFZA 2.966 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii B49 Type1 7 - 292 0 TPO165,SEP171 None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4DAWA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 0H2 Type1 249 - 542 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 2HY81 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 1ST Type1 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE STK4 STK4_HUMAN 6YATB 2.58 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii OJ5 Type1 29 - 307 0 TPO177,TPO183 None Serine/threonine-protein kinase 4 Homo sapiens
STE TNIK TNIK_HUMAN 6RA5B 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 310 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FD 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8R7GC 2.09 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii YEE Type1 206 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 6UNPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BRAF BRAF_HUMAN 4MNFA 2.802 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OICC 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none nonTYR APEdihe_aaiii APEdist_nnni STU Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K72B 2.22 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6QY Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7GB 2.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6R0 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6LXYB 2.19 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGDA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U9AA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3HMMA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 855 Type1 201 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3TZMA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii 085 Type1 200 - 496 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5QINA 1.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_niii J2V Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFA 3.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFB 3.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 6B5JB 2.97 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TYR CSK CSK_HUMAN 3D7UA 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
TYR CSK CSK_HUMAN 3D7UC 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
TYR EGFR EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None G719S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6JX4A 2.531 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 696 - 1018 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7VRAA 2.41 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa I0A Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7VREA 2.507 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 7VH Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9KLWA 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L53 Type1 696 - 1019 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2J5FA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa DJK Type1 696 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa QP1 Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8G63A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa YXT Type1 696 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9DM8A 2.13 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa A1A6K Type1 696 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NGPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1BX7 Type1 698 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NHWA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYD Type1 698 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NISA 2.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYK Type1 696 - 1016 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NJ7A 2.53 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYL Type1 698 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NJNA 2.24 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYS Type1 698 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VO7 Type1 697 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9OS6A 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1CEA Type1 697 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9H46A 3.163 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1ISA Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ZRT Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZAUA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 698 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7B85A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 697 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6S9BA 3.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1H Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6S9CA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1K Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ4A 2.78 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QW Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ7A 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3R1 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QS Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5C8KA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YV Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5C8MA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YW Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5C8NA 2.401 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YX Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CALA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4Z8 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CANA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZB Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAOA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4ZG Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZH Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EM7A 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q4 Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HCXA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60B Type1 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HCZA 2.62 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60E Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITTA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa AEE Type1 697 - 1019 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X26A 2.951 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XO Type1 697 - 1020 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XR Type1 697 - 1020 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XU Type1 697 - 1020 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5XDLA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8JC Type1 696 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9U8CD 3.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L8T Type1 696 - 987 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa FZP Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 3QY Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZJ Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZQ Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZR Type1.5_Back 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60D Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 63N Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9VA 1.458 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa AGS ATPlike 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 1MQBB 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 602 - 883 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJAB 1.75 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ACP ATPlike 590 - 965 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA0A 1.948 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa A5B Type1 604 - 889 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKAA 1.377 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa 91H Type1 605 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNHC 1.379 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa DXK Type1 600 - 890 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QOQA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 595 - 906 0 PTR701 None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2GSFA 1.77 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None A608T Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 2QOKA 1.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F,S768A Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4GK3A 1.898 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa L87 Type1 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4P5QA 1.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa Q0B Type1 609 - 904 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4TWOA 2.047 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37W Type1 609 - 906 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4G2FA 1.699 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa C07 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4GK2A 2.195 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L66 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4GK4A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L90 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA7 EPHA7_HUMAN 7EEDA 3.05 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None D751H Ephrin type-A receptor 7 Homo sapiens
TYR EPHA7 EPHA7_HUMAN 2REIA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None None Ephrin type-A receptor 7 Homo sapiens
TYR EPHA7 EPHA7_HUMAN 7EECA 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None G656R Ephrin type-A receptor 7 Homo sapiens
TYR EPHA8 EPHA8_HUMAN 3KULA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 627 - 900 0 None None Ephrin type-A receptor 8 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 3ZFXB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 3ZFXC 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 614 - 892 0 None None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 3ZFXF 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 612 - 893 0 None None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 3ZFXG 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 5MJAA 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 7O3 Type1.5_Back 609 - 892 0 PTR647,PTR778 None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNLA 1.269 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 3ZEWA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STU Type1 609 - 888 0 PTR774 None Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 3ZEWB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none none-none TYR APEdihe_nniai APEdist_aaaa STU Type1 609 - 887 0 PTR774 None Ephrin type-B receptor 4 Homo sapiens
TYR FES FES_HUMAN 4E93A 1.84 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GUI Type1 448 - 822 0 None None Tyrosine-protein kinase Fes/Fps Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LVPD 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor Homo sapiens
TYR ITK ITK_HUMAN 3QGYB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L7O Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4D1SA 1.66 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa BJG Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5USYA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5USYB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6HZVA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6HZVB 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1099 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6HZVC 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6HZVD 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 5W86A 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 5W86B 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 816 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 5W86C 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 5W86D 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6AAKD 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9T6 Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6B 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa VFC Type1 813 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6C 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6D 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZEPB 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZEPC 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZEPD 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 7UYVD 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 5VO6A 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9J4 Type1 815 - 1099 0 None C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6NY4A 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa Z3A Type1 815 - 1099 0 None C811S,C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4V0GB 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 816 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4V0GA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 817 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4Z16A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4Z16C 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4Z16D 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4QPSA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37Q Type1 814 - 1100 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4QPSC 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 37Q Type1 814 - 1102 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6GLAA 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6GLAB 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6GLBA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 6GLBB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 9R5ZA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 822 - 1101 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 9R5ZB 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 816 - 1101 0 None None Tyrosine-protein kinase JAK3 Homo sapiens
TYR KIT KIT_HUMAN 1PKGB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ADP ATPlike 566 - 929 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8PQBA 1.87 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9XO Type1 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8PQEB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9WU Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR PTK2 FAK1_HUMAN 6YVYB 1.918 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa P1E Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR SRC SRC_HUMAN 6E6EH 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 4MXOA 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 4MXOB 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 6ATEA 2.402 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 6H3 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SYK KSYK_HUMAN 1XBBA 1.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STI Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 3FQHB 2.26 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 057 Type1 363 - 633 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 3FQSA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 585 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4FYNA 2.318 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4FZ6A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4I0RA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B4 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4I0SA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B5 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 4I0TA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1B6 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 5T68A 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 5T68B 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 5Y5UB 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8OU Type1 363 - 629 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 3VF8A 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 0JE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 3VF9A 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 477 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 6ZCRA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR SYK KSYK_HUMAN 6ZCUA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR TNK2 ACK1_HUMAN 1U4DA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DBQ Type1 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 7UYSA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa OVC Type1 890 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 7UYUA 2.05 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa OV0 Type1 889 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6AAMA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9T6 Type1 888 - 1178 0 None C936A,Q969A,E971A,K972A,D1023N,I1114L,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
AGC PRKCI KPCI_MOUSE 4DC2A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 248 - 586 0 TPO563 None Protein kinase C iota type Mus musculus
CAMK MELK MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CAMK MELK MELK_MOUSE 4CQGA 2.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii OT5 Type1 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZH 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M66B 2.401 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 313 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2B 2.39 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1D99 Type1 15 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0B 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn A1D99 Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGA 2.03 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn LKR Type1 14 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGB 2.03 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LKR Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHA 2.38 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHB 2.38 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
CMGC MAPK1 MK01_RAT 3C9WA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
TYR CSK CSK_RAT 1K9AA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CK1 HRR25 HRR25_YEAST 5CYZA 1.841 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 388 0 None K38R Casein kinase I homolog HRR25 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2F9GA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 1 - 353 0 PTR182 None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WWAA 2.953 None DFGin‑BLAminus DFGAsp-rot-in in-none in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 4 - 253 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus DFGAsp-rot-in out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0A 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ADP, QUE ATPlike, Allosteric 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0B 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP, QUE ATPlike, Allosteric 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1A 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1B 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER ROP18 ROP18_TOXGO 4JRNA 2.71 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_inni ANP Allosteric 187 - 548 0 None None Serine/threonine-protein kinase ROP18 Toxoplasma gondii

Activity: None (unassigned)

Total number of chains: 50
Active chains: 0
Total number of genes: 17
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 50 100.0% 5NTJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL FERONIA FERON_ARATH 9UBIB 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni OT5 Type1 521 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOD 2.502 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC PRKACA KAPCA_BOVIN 9DW8G 3.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 329 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_CRIGR 6EH2A 1.76 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5NTJA 1.56 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERUA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERVA 2.06 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y2OA 2.01 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii O72 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
TYR SRC SRC_CHICK 2OIQB 2.07 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3EL8B 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6HVEA 1.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GUW Type1 256 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F6XA 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa IHH Type1 255 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F6XD 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa IHH Type1 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4O2PB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 11V Type1 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5XP7B 2.012 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 8C6 Type1 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4MCVA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 29K Type1 256 - 533 0 None T338G Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC PRKCI KPCI_MOUSE 4DC2A 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 248 - 586 0 TPO563 None Protein kinase C iota type Mus musculus
CAMK MELK MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CAMK MELK MELK_MOUSE 4CQGA 2.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii OT5 Type1 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZH 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M66B 2.401 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 313 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2B 2.39 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1D99 Type1 15 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0B 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn A1D99 Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGA 2.03 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn LKR Type1 14 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGB 2.03 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LKR Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHA 2.38 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHB 2.38 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENB 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HENC 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
TYR EPHB2 EPHB2_MOUSE 2HEND 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 614 - 893 0 None D746A Ephrin type-B receptor 2 Mus musculus
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
CMGC MAPK1 MK01_RAT 3C9WA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
TYR CSK CSK_RAT 1K9AA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CK1 HRR25 HRR25_YEAST 5CYZA 1.841 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 388 0 None K38R Casein kinase I homolog HRR25 Saccharomyces cerevisiae
CMGC FUS3 FUS3_YEAST 2F9GA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 1 - 353 0 PTR182 None Mitogen-activated protein kinase FUS3 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WWAA 2.953 None DFGin‑BLAminus DFGAsp-rot-in in-none in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 4 - 253 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus DFGAsp-rot-in out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0A 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ADP, QUE ATPlike, Allosteric 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0B 3.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP, QUE ATPlike, Allosteric 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1A 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1B 3.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER ROP18 ROP18_TOXGO 4JRNA 2.71 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_inni ANP Allosteric 187 - 548 0 None None Serine/threonine-protein kinase ROP18 Toxoplasma gondii