TYR_PTK2 (Focal adhesion kinase 1)

Total number of chains: 53
Active chains: 2
Uniprot: FAK1_HUMAN
Kinase Domain Residues: 422 - 678
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 27 50.9% 4GU6A
DFGin BLAminus 9 17.0% AF-Q05397-K1A
DFGin ABAminus 7 13.2% 6YVYA
DFGout None 3 5.7% 4K9YA
None None 3 5.7% 6YVSC
DFGout BBAminus 2 3.8% 4KAOB
DFGin BLBminus 1 1.9% 2IJMB
DFGinter None 1 1.9% 4EBWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q05397-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1
AF-Q05397-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1
9SDIA 2.53 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao A1JNJ Type1 414 - 686 0 None None Focal adhesion kinase 1
3PXKA 1.79 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PXK Type1 415 - 687 0 None P410G Focal adhesion kinase 1
3PXKB 1.79 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nniai APEdist_aaai PXK Type1 414 - 687 0 None P410G Focal adhesion kinase 1
6YT6A 1.537 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
6YT6B 1.537 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_niiai APEdist_aaai PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
6YVSA 1.81 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai PVT Type1 414 - 686 0 None None Focal adhesion kinase 1
6YVYA 1.918 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai P1E Type1 412 - 686 0 None None Focal adhesion kinase 1
4GU9B 2.4 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 4GU Type1 415 - 683 0 None None Focal adhesion kinase 1
4K8AA 2.91 Inactive DFGin‑BLAminus in-out none-out TYR APEdihe_nniai APEdist_aaao K8A Type1 414 - 683 0 None None Focal adhesion kinase 1
4K8AB 2.91 Inactive DFGin‑BLAminus in-out out-out TYR APEdihe_nniai APEdist_aaao K8A Type1 414 - 684 0 None None Focal adhesion kinase 1
4KABB 2.71 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 4KA Type1 414 - 684 0 None None Focal adhesion kinase 1
2ETMA 2.3 Inactive DFGin‑BLAminus in-out out-out TYR APEdihe_niiai APEdist_aaao 7PY Type1 415 - 686 0 None None Focal adhesion kinase 1
2ETMB 2.3 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nnoai APEdist_aaao 7PY Type1 413 - 689 0 None None Focal adhesion kinase 1
6YVYB 1.918 Inactive DFGin‑BLAminus in-in none-out TYR APEdihe_nniai APEdist_aaao P1E Type1 415 - 686 0 None None Focal adhesion kinase 1
2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1
2IJMA 2.187 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 414 - 688 0 None None Focal adhesion kinase 1
7PI4DDD 2.24 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 687 0 None None Focal adhesion kinase 1
9SDIB 2.53 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 414 - 685 0 None None Focal adhesion kinase 1
3BZ3A 2.2 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao YAM Type1 414 - 689 0 None None Focal adhesion kinase 1
4GU9A 2.4 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4GU Type1 414 - 685 0 None None Focal adhesion kinase 1
4KABA 2.71 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4KA Type1 412 - 686 0 None None Focal adhesion kinase 1
6I8ZA 1.99 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao H82 Type1 414 - 688 0 None None Focal adhesion kinase 1
4I4EA 1.55 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao 1BQ Type1 414 - 686 0 None None Focal adhesion kinase 1
4GU6A 1.95 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao 10N Type1 414 - 686 0 None None Focal adhesion kinase 1
4GU6B 1.95 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 10N Type1 415 - 686 0 None None Focal adhesion kinase 1
6YOJA 1.361 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai P4N Type1 414 - 686 0 None None Focal adhesion kinase 1
6YQ1A 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P7N Type1 415 - 686 0 None None Focal adhesion kinase 1
6YQ1B 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao P7N Type1 411 - 686 0 None None Focal adhesion kinase 1
6YQ1C 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P7N Type1 412 - 686 0 None None Focal adhesion kinase 1
6YQ1D 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P7N Type1 415 - 686 0 None None Focal adhesion kinase 1
6YR9A 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P9K Type1 415 - 686 0 None None Focal adhesion kinase 1
6YR9B 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P9K Type1 414 - 684 0 None None Focal adhesion kinase 1
6YR9C 1.925 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao P9K Type1 414 - 686 0 None None Focal adhesion kinase 1
6YR9D 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P9K Type1 412 - 685 0 None None Focal adhesion kinase 1
6YVSB 1.81 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 415 - 686 0 None None Focal adhesion kinase 1
6YVSD 1.81 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 412 - 686 0 None None Focal adhesion kinase 1
6YVYC 1.918 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao P1E Type1 411 - 686 0 None None Focal adhesion kinase 1
6YVYD 1.918 Inactive DFGin‑None in-out none-out TYR APEdihe_niiai APEdist_aaao P1E Type1 415 - 686 0 None None Focal adhesion kinase 1
6YXVA 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1
6YXVB 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1
6YXVC 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1
6YXVD 2.298 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1
4EBWA 2.65 Inactive DFGinter‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 0PF Type1 411 - 686 0 None None Focal adhesion kinase 1
4KAOA 2.39 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 415 - 686 0 None P410G Focal adhesion kinase 1
4KAOB 2.39 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 414 - 686 0 None P410G Focal adhesion kinase 1
4EBVA 1.67 Inactive DFGout‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 0O7 Type1 411 - 686 0 None None Focal adhesion kinase 1
4K9YA 2.0 Inactive DFGout‑None in-in out-out TYR APEdihe_oiiai APEdist_aaao K9Y Type2 415 - 685 0 None None Focal adhesion kinase 1
4I4FA 1.75 Inactive DFGout‑None out-out none-out TYR APEdihe_niiai APEdist_aaao 1BR Type3 415 - 686 0 None None Focal adhesion kinase 1
1MP8A 1.6 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 414 - 686 0 None None Focal adhesion kinase 1
4Q9SA 2.07 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 30G Type1 414 - 686 0 None None Focal adhesion kinase 1
6YVSC 1.81 Inactive None‑None in-out none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 414 - 686 0 None None Focal adhesion kinase 1

TYR_PTK2 (Focal adhesion kinase 1)

Total number of chains: 87
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 50 57.5% 4GU6A
DFGin ABAminus 14 16.1% 6YVYA
DFGin BLAminus 13 14.9% AF-Q05397-K1A
DFGout None 3 3.4% 4K9YA
None None 3 3.4% 6YVSC
DFGout BBAminus 2 2.3% 4KAOB
DFGin BLBminus 1 1.1% 2IJMB
DFGinter None 1 1.1% 4EBWA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4VA 2.1 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4YB 1.8 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5HB 1.75 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5KB 1.75 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4VB 2.1 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KB8 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0LA 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao ANP ATPlike 411 - 686 0 PTR576,PTR577 None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4RA 1.55 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 414 - 685 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4RB 1.55 Inactive DFGin‑None out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 412 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4SA 2.0 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4YA 1.8 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D58A 1.95 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5KA 1.75 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY3A 6.32 Inactive DFGin‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY3B 6.32 Inactive DFGin‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKMA 2.31 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao BII Type1 413 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0MB 2.8 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKQA 2.6 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai VG8 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKKA 2.0 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKOA 1.65 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai BIJ Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4BRXA 2.05 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao KGW Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4C7TA 2.05 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai 5RI Type1 414 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5HA 1.75 Inactive DFGin‑None in-out none-out TYR APEdihe_niiai APEdist_aaao 9RM Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCRA 2.3 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUW Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCWA 2.0 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao EUQ Type1 414 - 685 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCWB 2.0 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUQ Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCXA 1.553 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUW Type1 413 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0JA 2.8 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0KA 3.0 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0KB 3.0 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D55A 2.3 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 413 - 685 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_HUMAN AF-Q05397-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN AF-Q05397-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 9SDIA 2.53 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao A1JNJ Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 3PXKA 1.79 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PXK Type1 415 - 687 0 None P410G Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 3PXKB 1.79 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nniai APEdist_aaai PXK Type1 414 - 687 0 None P410G Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YT6A 1.537 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PKE Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YT6B 1.537 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_niiai APEdist_aaai PKE Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVSA 1.81 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai PVT Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVYA 1.918 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai P1E Type1 412 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4GU9B 2.4 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 4GU Type1 415 - 683 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4K8AA 2.91 Inactive DFGin‑BLAminus in-out none-out TYR APEdihe_nniai APEdist_aaao K8A Type1 414 - 683 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4K8AB 2.91 Inactive DFGin‑BLAminus in-out out-out TYR APEdihe_nniai APEdist_aaao K8A Type1 414 - 684 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4KABB 2.71 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 4KA Type1 414 - 684 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 2ETMA 2.3 Inactive DFGin‑BLAminus in-out out-out TYR APEdihe_niiai APEdist_aaao 7PY Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 2ETMB 2.3 Inactive DFGin‑BLAminus in-in out-out TYR APEdihe_nnoai APEdist_aaao 7PY Type1 413 - 689 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVYB 1.918 Inactive DFGin‑BLAminus in-in none-out TYR APEdihe_nniai APEdist_aaao P1E Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 2IJMA 2.187 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ATP ATPlike 414 - 688 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 7PI4DDD 2.24 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 687 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 9SDIB 2.53 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 414 - 685 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 3BZ3A 2.2 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao YAM Type1 414 - 689 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4GU9A 2.4 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4GU Type1 414 - 685 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4KABA 2.71 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4KA Type1 412 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6I8ZA 1.99 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao H82 Type1 414 - 688 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4I4EA 1.55 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao 1BQ Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4GU6A 1.95 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao 10N Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4GU6B 1.95 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 10N Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YOJA 1.361 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai P4N Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YQ1A 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P7N Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YQ1B 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao P7N Type1 411 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YQ1C 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P7N Type1 412 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YQ1D 1.784 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P7N Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YR9A 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P9K Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YR9B 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_niiai APEdist_aaao P9K Type1 414 - 684 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YR9C 1.925 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao P9K Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YR9D 1.925 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao P9K Type1 412 - 685 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVSB 1.81 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVSD 1.81 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 412 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVYC 1.918 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao P1E Type1 411 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVYD 1.918 Inactive DFGin‑None in-out none-out TYR APEdihe_niiai APEdist_aaao P1E Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YXVA 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YXVB 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YXVC 2.298 Inactive DFGin‑None in-in out-out TYR APEdihe_iiiai APEdist_aaao Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YXVD 2.298 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4EBWA 2.65 Inactive DFGinter‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 0PF Type1 411 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4KAOA 2.39 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 415 - 686 0 None P410G Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4KAOB 2.39 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 414 - 686 0 None P410G Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4EBVA 1.67 Inactive DFGout‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 0O7 Type1 411 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4K9YA 2.0 Inactive DFGout‑None in-in out-out TYR APEdihe_oiiai APEdist_aaao K9Y Type2 415 - 685 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4I4FA 1.75 Inactive DFGout‑None out-out none-out TYR APEdihe_niiai APEdist_aaao 1BR Type3 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 1MP8A 1.6 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 4Q9SA 2.07 Inactive None‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 30G Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
FAK1_HUMAN 6YVSC 1.81 Inactive None‑None in-out none-out TYR APEdihe_nniai APEdist_aaao PVT Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens

TYR_PTK2 (Focal adhesion kinase 1)

Total number of chains: 34
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 23 67.6% 4D4RB
DFGin ABAminus 7 20.6% 4D5HB
DFGin BLAminus 4 11.8% 2J0LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4VA 2.1 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4YB 1.8 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5HB 1.75 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5KB 1.75 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4VB 2.1 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KB8 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0LA 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao ANP ATPlike 411 - 686 0 PTR576,PTR577 None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4RA 1.55 Inactive DFGin‑None in-out none-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 414 - 685 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4RB 1.55 Inactive DFGin‑None out-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 412 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4SA 2.0 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D4YA 1.8 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D58A 1.95 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5KA 1.75 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY3A 6.32 Inactive DFGin‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6TY3B 6.32 Inactive DFGin‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKMA 2.31 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao BII Type1 413 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0MB 2.8 Inactive DFGin‑None in-in none-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKQA 2.6 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai VG8 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKKA 2.0 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2JKOA 1.65 Inactive DFGin‑None in-in none-none TYR APEdihe_nniai APEdist_aaai BIJ Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4BRXA 2.05 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao KGW Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4C7TA 2.05 Inactive DFGin‑None in-in out-none TYR APEdihe_nniai APEdist_aaai 5RI Type1 414 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D5HA 1.75 Inactive DFGin‑None in-out none-out TYR APEdihe_niiai APEdist_aaao 9RM Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCRA 2.3 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUW Type1 413 - 684 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCWA 2.0 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao EUQ Type1 414 - 685 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCWB 2.0 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUQ Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 6GCXA 1.553 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao EUW Type1 413 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0JA 2.8 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0KA 3.0 Inactive DFGin‑None in-in none-out TYR APEdihe_niiai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 2J0KB 3.0 Inactive DFGin‑None in-in out-out TYR APEdihe_nniai APEdist_aaao 4ST Type1 35 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
FAK1_CHICK 4D55A 2.3 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 413 - 685 0 None None Focal adhesion kinase 1 Gallus gallus