CSNK2A2 (Casein kinase II subunit alpha')

Group: CMGC
Uniprot: CSK22_HUMAN
Domain boundary: 40 - 325


Total number of chains: 46
Spatial Dihedral Chains Representative
DFGin BLAminus 45 AF-P19784-K1A
DFGin None 1 3E3BX
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8Q77A 1.255 Active DFGin BLAminus in-in in-in LN3 LN3 Allosteric Type1 7 - 334 C336S None 0
8QBUA 1.09 Active DFGin BLAminus in-in in-in 42J 3NG Allosteric Type1 6 - 333 C336S None 0
7AT9A 1.05 Active DFGin BLAminus in-in in-in 42J 4B0 42J Allosteric Type1 Allosteric 6 - 333 None None 0
AF-P19784-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 32 - 333 None None 0
8QF1B 1.32 Active DFGin BLAminus in-in in-in No_ligand No_ligand 7 - 333 C336S None 0
6QY8A 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 330 None None 0
6QY8B 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
6QY8C 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
6QY8D 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
6QY9A 1.5 Active DFGin BLAminus in-in in-in JL2 Type1 7 - 335 None None 0
6L20A 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
6L20D 3.087 Inactive DFGin BLAminus in-out in-in E3U Type1 8 - 332 None None 0
6L20G 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
6L20J 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
5Y9MA 2.006 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
5Y9MX 2.006 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
5YF9B 1.89 Active DFGin BLAminus in-in in-in NIO Type1 6 - 329 None None 0
5YF9X 1.89 Active DFGin BLAminus in-in in-in NIO Type1 6 - 329 None None 0
5YWMX 1.939 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
7XYHA 2.04 Active DFGin BLAminus in-in in-in 8BH Type1 8 - 332 None None 0
7XYHB 2.04 Active DFGin BLAminus in-in in-in 8BH Type1 8 - 332 None None 0
3OFMA 2.0 Active DFGin BLAminus in-in in-in 4B0 Type1 8 - 332 C336S None 0
5OOIA 1.998 Active DFGin BLAminus in-in in-in 9YE Type1 5 - 333 C336S None 0
5OOIB 1.998 Active DFGin BLAminus in-in in-in 9YE Type1 7 - 331 C336S None 0
6HMBA 1.04 Active DFGin BLAminus in-in in-in 3NG Type1 7 - 334 C336S None 0
6HMCA 1.03 Active DFGin BLAminus in-in in-in FXB Type1 7 - 333 C336S None 0
6HMQA 0.97 Active DFGin BLAminus in-in in-in 4B0 Type1 7 - 333 C336S None 0
6TE2A 0.922 Active DFGin BLAminus in-in in-in N4N Type1 7 - 333 C336S None 0
6TEWA 1.082 Active DFGin BLAminus in-in in-in N5Q Type1 8 - 332 C336S None 0
6TGUA 0.833 Active DFGin BLAminus in-in in-in N92 Type1 7 - 333 C336S None 0
7A1BA 1.287 Active DFGin BLAminus in-in in-in QXW Type1 7 - 333 C336S None 0
7A1ZA 1.024 Active DFGin BLAminus in-in in-in QWN Type1 7 - 334 None None 0
7A22A 1.01 Active DFGin BLAminus in-in in-in QWW Type1 6 - 333 None None 0
7A2HA 1.01 Active DFGin BLAminus in-in in-in QX2 Type1 7 - 331 None None 0
7ATVA 0.98 Active DFGin BLAminus in-in in-in RXE Type1 7 - 334 None None 0
8Q9SA 1.352 Active DFGin BLAminus in-in in-in QBE Type1 7 - 333 C336S None 0
8QCDA 1.03 Active DFGin BLAminus in-in in-in TBS Type1 7 - 333 C336S None 0
8QCGA 1.04 Inactive DFGin BLAminus in-out in-in ANP Type1 7 - 330 C336S None 0
8QCGB 1.04 Active DFGin BLAminus in-in in-in ANP Type1 7 - 333 C336S None 0
8QF1A 1.32 Active DFGin BLAminus in-in in-in GNP Type1 7 - 329 C336S None 0
5M4UA 2.195 Active DFGin BLAminus in-in in-in 7FC Type1 3 - 334 D39G,C336S None 0
5M56A 2.237 Active DFGin BLAminus in-in in-in 7FC Type1 2 - 332 D39G,C336S None 0
5M56B 2.237 Active DFGin BLAminus in-in in-in 7FC Type1 6 - 333 D39G,C336S None 0
6HMDA 1.0 Active DFGin BLAminus in-in in-in GDW Type1 7 - 334 C336S None 0
9HK5A 1.491 Active DFGin BLAminus in-in in-in 3NG Type1 7 - 334 P32V,V83I,T101I,C336S None 0
3E3BX 3.2 Inactive DFGin None in-in in-in CCK Type1 1 - 334 None None 0

CSNK2A2 (Casein kinase II subunit alpha')

Group: CMGC
Total number of chains: 46
Spatial Dihedral Chains Representative
DFGin BLAminus 45 AF-P19784-K1A
DFGin None 1 3E3BX
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens CSK22_HUMAN 8Q77A 1.255 Active DFGin BLAminus in-in in-in LN3 LN3 Allosteric Type1 7 - 334 C336S None 0
Homo sapiens CSK22_HUMAN 8QBUA 1.09 Active DFGin BLAminus in-in in-in 42J 3NG Allosteric Type1 6 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 7AT9A 1.05 Active DFGin BLAminus in-in in-in 42J 4B0 42J Allosteric Type1 Allosteric 6 - 333 None None 0
Homo sapiens CSK22_HUMAN AF-P19784-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 32 - 333 None None 0
Homo sapiens CSK22_HUMAN 8QF1B 1.32 Active DFGin BLAminus in-in in-in No_ligand No_ligand 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 6QY8A 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 330 None None 0
Homo sapiens CSK22_HUMAN 6QY8B 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6QY8C 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6QY8D 1.7 Active DFGin BLAminus in-in in-in 041 Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6QY9A 1.5 Active DFGin BLAminus in-in in-in JL2 Type1 7 - 335 None None 0
Homo sapiens CSK22_HUMAN 6L20A 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6L20D 3.087 Inactive DFGin BLAminus in-out in-in E3U Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6L20G 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 6L20J 3.087 Active DFGin BLAminus in-in in-in E3U Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 5Y9MA 2.006 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
Homo sapiens CSK22_HUMAN 5Y9MX 2.006 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
Homo sapiens CSK22_HUMAN 5YF9B 1.89 Active DFGin BLAminus in-in in-in NIO Type1 6 - 329 None None 0
Homo sapiens CSK22_HUMAN 5YF9X 1.89 Active DFGin BLAminus in-in in-in NIO Type1 6 - 329 None None 0
Homo sapiens CSK22_HUMAN 5YWMX 1.939 Active DFGin BLAminus in-in in-in NIO Type1 7 - 329 None None 0
Homo sapiens CSK22_HUMAN 7XYHA 2.04 Active DFGin BLAminus in-in in-in 8BH Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 7XYHB 2.04 Active DFGin BLAminus in-in in-in 8BH Type1 8 - 332 None None 0
Homo sapiens CSK22_HUMAN 3OFMA 2.0 Active DFGin BLAminus in-in in-in 4B0 Type1 8 - 332 C336S None 0
Homo sapiens CSK22_HUMAN 5OOIA 1.998 Active DFGin BLAminus in-in in-in 9YE Type1 5 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 5OOIB 1.998 Active DFGin BLAminus in-in in-in 9YE Type1 7 - 331 C336S None 0
Homo sapiens CSK22_HUMAN 6HMBA 1.04 Active DFGin BLAminus in-in in-in 3NG Type1 7 - 334 C336S None 0
Homo sapiens CSK22_HUMAN 6HMCA 1.03 Active DFGin BLAminus in-in in-in FXB Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 6HMQA 0.97 Active DFGin BLAminus in-in in-in 4B0 Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 6TE2A 0.922 Active DFGin BLAminus in-in in-in N4N Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 6TEWA 1.082 Active DFGin BLAminus in-in in-in N5Q Type1 8 - 332 C336S None 0
Homo sapiens CSK22_HUMAN 6TGUA 0.833 Active DFGin BLAminus in-in in-in N92 Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 7A1BA 1.287 Active DFGin BLAminus in-in in-in QXW Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 7A1ZA 1.024 Active DFGin BLAminus in-in in-in QWN Type1 7 - 334 None None 0
Homo sapiens CSK22_HUMAN 7A22A 1.01 Active DFGin BLAminus in-in in-in QWW Type1 6 - 333 None None 0
Homo sapiens CSK22_HUMAN 7A2HA 1.01 Active DFGin BLAminus in-in in-in QX2 Type1 7 - 331 None None 0
Homo sapiens CSK22_HUMAN 7ATVA 0.98 Active DFGin BLAminus in-in in-in RXE Type1 7 - 334 None None 0
Homo sapiens CSK22_HUMAN 8Q9SA 1.352 Active DFGin BLAminus in-in in-in QBE Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 8QCDA 1.03 Active DFGin BLAminus in-in in-in TBS Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 8QCGA 1.04 Inactive DFGin BLAminus in-out in-in ANP Type1 7 - 330 C336S None 0
Homo sapiens CSK22_HUMAN 8QCGB 1.04 Active DFGin BLAminus in-in in-in ANP Type1 7 - 333 C336S None 0
Homo sapiens CSK22_HUMAN 8QF1A 1.32 Active DFGin BLAminus in-in in-in GNP Type1 7 - 329 C336S None 0
Homo sapiens CSK22_HUMAN 5M4UA 2.195 Active DFGin BLAminus in-in in-in 7FC Type1 3 - 334 D39G,C336S None 0
Homo sapiens CSK22_HUMAN 5M56A 2.237 Active DFGin BLAminus in-in in-in 7FC Type1 2 - 332 D39G,C336S None 0
Homo sapiens CSK22_HUMAN 5M56B 2.237 Active DFGin BLAminus in-in in-in 7FC Type1 6 - 333 D39G,C336S None 0
Homo sapiens CSK22_HUMAN 6HMDA 1.0 Active DFGin BLAminus in-in in-in GDW Type1 7 - 334 C336S None 0
Homo sapiens CSK22_HUMAN 9HK5A 1.491 Active DFGin BLAminus in-in in-in 3NG Type1 7 - 334 P32V,V83I,T101I,C336S None 0
Homo sapiens CSK22_HUMAN 3E3BX 3.2 Inactive DFGin None in-in in-in CCK Type1 1 - 334 None None 0

CSNK2A2 (Casein kinase II subunit alpha')

No non-human structures known.