CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 70
Active chains: 24
Uniprot: CSK22_HUMAN
Kinase Domain Residues: 40 - 325
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 69 98.6% AF-P19784-K1A
DFGin None 1 1.4% 3E3BX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha'
9R5CA 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JCZ, 4B0 Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
AF-P19784-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 333 0 None None Casein kinase II subunit alpha'
AF-P19784-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 333 0 None None Casein kinase II subunit alpha'
8QF1B 1.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 333 0 None C336S Casein kinase II subunit alpha'
6QY8A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 330 0 None None Casein kinase II subunit alpha'
6QY8B 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha'
6QY8C 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha'
6QY8D 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha'
6QY9A 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JL2 Type1 7 - 335 0 None None Casein kinase II subunit alpha'
6L20G 3.087 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha'
6L20J 3.087 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha'
5Y9MA 2.006 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha'
5Y9MX 2.006 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha'
5YF9B 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 6 - 329 0 None None Casein kinase II subunit alpha'
5YF9X 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 6 - 329 0 None None Casein kinase II subunit alpha'
5YWMX 1.939 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha'
3OFMA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4B0 Type1 8 - 332 0 None C336S Casein kinase II subunit alpha'
7ATVA 0.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXE Type1 7 - 334 0 None None Casein kinase II subunit alpha'
5M4UA 2.195 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7FC Type1 3 - 334 0 None D39G,C336S Casein kinase II subunit alpha'
5M56B 2.237 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7FC Type1 6 - 333 0 None D39G,C336S Casein kinase II subunit alpha'
6HMDA 1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GDW Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
9R5BA 1.09 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JCY, A1JCY Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
9IHGA 1.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SYA, SYA Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
8QCGA 1.04 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 330 0 None C336S Casein kinase II subunit alpha'
8Q77A 1.255 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii LN3, LN3 Allosteric, Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
8QBUA 1.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 42J, 3NG Allosteric, Type1 6 - 333 0 None C336S Casein kinase II subunit alpha'
9IHIA 1.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii SY4, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9Q9BA 1.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VN9, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9QB6A 1.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RDV, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
7AT9A 1.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 42J, 4B0, 42J Allosteric, Type1, Allosteric 6 - 333 0 None None Casein kinase II subunit alpha'
9QABA 0.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RA7, 3NG, RA7 Allosteric, Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
6L20A 3.087 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha'
6L20D 3.087 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha'
7XYHA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 8BH Type1 8 - 332 0 None None Casein kinase II subunit alpha'
7XYHB 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 8BH Type1 8 - 332 0 None None Casein kinase II subunit alpha'
5OOIA 1.998 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 9YE Type1 5 - 333 0 None C336S Casein kinase II subunit alpha'
5OOIB 1.998 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 9YE Type1 7 - 331 0 None C336S Casein kinase II subunit alpha'
6HMBA 1.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
6HMCA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii FXB Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
6HMQA 0.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 4B0 Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
6TE2A 0.922 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N4N Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
6TEWA 1.082 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N5Q Type1 8 - 332 0 None C336S Casein kinase II subunit alpha'
6TGUA 0.833 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N92 Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
7A1BA 1.287 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QXW Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
7A1ZA 1.024 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QWN Type1 7 - 334 0 None None Casein kinase II subunit alpha'
7A22A 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QWW Type1 6 - 333 0 None None Casein kinase II subunit alpha'
7A2HA 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QX2 Type1 7 - 331 0 None None Casein kinase II subunit alpha'
8Q9SA 1.352 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QBE Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
8QCDA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
8QF1A 1.32 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii GNP Type1 7 - 329 0 None C336S Casein kinase II subunit alpha'
9FBIA 1.161 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NIO Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9FBIB 1.161 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NIO Type1 5 - 333 0 None C336S Casein kinase II subunit alpha'
9GXYA 1.16 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IKB Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9H96A 1.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1ITG Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9R57A 1.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7M0 Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
9R5DA 1.02 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1JC0 Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
9R5FA 1.19 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1JCX Type1 6 - 334 0 None C336S Casein kinase II subunit alpha'
5M56A 2.237 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7FC Type1 2 - 332 0 None D39G,C336S Casein kinase II subunit alpha'
9Q8QA 0.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1I4N Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9Q9CA 1.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii R9D Type1 7 - 334 0 None C336S Casein kinase II subunit alpha'
9QAKA 0.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1I5I Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9QB0A 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii U8X Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'
9HK5A 1.491 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 7 - 334 0 None P32V,V83I,T101I,C336S Casein kinase II subunit alpha'
9Q9AA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, A1I4V Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
9Q9DA 0.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, R9G Type1, Allosteric 7 - 332 0 None C336S Casein kinase II subunit alpha'
9QAGA 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, RBJ Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
9Q8CA 0.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii T9Y, T9Y, T9Y Type1, Allosteric, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
9Q9GA 0.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii R9J, R9J, R9J Type1, Allosteric, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha'
3E3BX 3.2 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CCK Type1 1 - 334 0 None None Casein kinase II subunit alpha'

CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 70
Active chains: 24
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 69 98.6% AF-P19784-K1A
DFGin None 1 1.4% 3E3BX
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CSK22_HUMAN 8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9R5CA 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JCZ, 4B0 Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN AF-P19784-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 333 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN AF-P19784-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 333 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8QF1B 1.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6QY8A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 330 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6QY8B 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6QY8C 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6QY8D 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 041 Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6QY9A 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JL2 Type1 7 - 335 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6L20G 3.087 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6L20J 3.087 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5Y9MA 2.006 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5Y9MX 2.006 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5YF9B 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 6 - 329 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5YF9X 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 6 - 329 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5YWMX 1.939 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NIO Type1 7 - 329 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 3OFMA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4B0 Type1 8 - 332 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7ATVA 0.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXE Type1 7 - 334 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5M4UA 2.195 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7FC Type1 3 - 334 0 None D39G,C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5M56B 2.237 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7FC Type1 6 - 333 0 None D39G,C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6HMDA 1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GDW Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9R5BA 1.09 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JCY, A1JCY Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9IHGA 1.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SYA, SYA Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8QCGA 1.04 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 330 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8Q77A 1.255 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii LN3, LN3 Allosteric, Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8QBUA 1.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 42J, 3NG Allosteric, Type1 6 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9IHIA 1.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii SY4, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q9BA 1.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VN9, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9QB6A 1.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RDV, 3NG Allosteric, Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7AT9A 1.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 42J, 4B0, 42J Allosteric, Type1, Allosteric 6 - 333 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9QABA 0.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RA7, 3NG, RA7 Allosteric, Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6L20A 3.087 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6L20D 3.087 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7XYHA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 8BH Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7XYHB 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 8BH Type1 8 - 332 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5OOIA 1.998 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 9YE Type1 5 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5OOIB 1.998 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 9YE Type1 7 - 331 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6HMBA 1.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6HMCA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii FXB Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6HMQA 0.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 4B0 Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6TE2A 0.922 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N4N Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6TEWA 1.082 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N5Q Type1 8 - 332 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 6TGUA 0.833 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii N92 Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7A1BA 1.287 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QXW Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7A1ZA 1.024 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QWN Type1 7 - 334 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7A22A 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QWW Type1 6 - 333 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 7A2HA 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QX2 Type1 7 - 331 0 None None Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8Q9SA 1.352 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QBE Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8QCDA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 8QF1A 1.32 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii GNP Type1 7 - 329 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9FBIA 1.161 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NIO Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9FBIB 1.161 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NIO Type1 5 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9GXYA 1.16 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IKB Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9H96A 1.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1ITG Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9R57A 1.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7M0 Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9R5DA 1.02 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1JC0 Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9R5FA 1.19 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1JCX Type1 6 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 5M56A 2.237 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 7FC Type1 2 - 332 0 None D39G,C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q8QA 0.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1I4N Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q9CA 1.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii R9D Type1 7 - 334 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9QAKA 0.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1I5I Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9QB0A 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii U8X Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9HK5A 1.491 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 7 - 334 0 None P32V,V83I,T101I,C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q9AA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, A1I4V Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q9DA 0.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, R9G Type1, Allosteric 7 - 332 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9QAGA 1.01 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG, RBJ Type1, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q8CA 0.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii T9Y, T9Y, T9Y Type1, Allosteric, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 9Q9GA 0.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii R9J, R9J, R9J Type1, Allosteric, Allosteric 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CSK22_HUMAN 3E3BX 3.2 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CCK Type1 1 - 334 0 None None Casein kinase II subunit alpha' Homo sapiens

CMGC_CSNK2A2 (Casein kinase II subunit alpha')

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism