TKL / All / All

Total number of chains: 1188
Active chains: 229
Total number of genes: 41
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 731 61.5% AF-Q04771-K1A
DFGout BBAminus 171 14.4% 8C7YA
DFGin BLBplus 87 7.3% 7M0XA
DFGin BLAplus 54 4.5% 9BP8A
DFGin None 34 2.9% 8GW3A
DFGout None 27 2.3% 8FO9E
DFGin BLBminus 25 2.1% 5CENA
DFGinter None 25 2.1% 9D5IA
None None 24 2.0% 6Q0JA
DFGin ABAminus 9 0.8% 6T6DB
DFGin BLBtrans 1 0.1% 6EGFB
All chains
No PyMOL session because the query has >1000 chains
Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL ACVR1 ACVR1_HUMAN 6T6DB 2.56 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MM8 Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T6DC 2.56 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 205 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCA 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCB 2.67 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii H8H Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCC 2.67 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi H8H Type1 201 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCD 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNQA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 206 - 496 0 None K493A Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNRA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 208 - 496 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SZMA 1.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi M2Z, M2Z, M2Z Allosteric, Allosteric, Type1 202 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7QB 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi XJM, LU8, XJM Allosteric, Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN AF-Q04771-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 505 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN AF-Q04771-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 505 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6JUXA 1.75 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi C9U Type1 203 - 499 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4DYMA 2.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IYZ Type1 207 - 499 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ACRA 2.01 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 9TO Type1 203 - 498 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ACRB 2.01 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 9TO Type1 203 - 498 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 7C3GA 1.802 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi FH0 Type1 203 - 499 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 7C3GB 1.802 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi FH0 Type1 204 - 499 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9L04A 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A1L4C Type1 203 - 499 0 None R206H Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3MTFA 2.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3MTFB 2.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3OOMA 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 507 Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UA 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UB 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UC 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UD 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGA 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGB 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGC 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 204 - 497 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4BGGD 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OXGA 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OXGB 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OXGC 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OXGD 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OY6A 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OY6B 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OY6C 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5OY6D 2.56 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S77B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S78B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S79B 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7GB 1.78 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8 Type1 207 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7HB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7JB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 206 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7PB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7WB 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S83B 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S84B 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 206 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S89B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GI6A 1.98 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi EZB Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GINA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IR2 Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GINB 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IR2 Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GIPA 2.17 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi EUN Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SRHA 1.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SZMB 1.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi M2Z Type1 205 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T6DD 2.56 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii MM8 Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T8NA 1.77 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MVE Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T8NB 1.77 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MVE Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6TN8A 1.63 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 5U6 Type1 204 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6Z36B 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi Q5Z Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 7A21A 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QWQ Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 7A21B 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QWQ Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 7NNSB 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi C87 Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8C7WA 2.26 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi U0C Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8C7ZA 2.23 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi TZX Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 205 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GC 2.09 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii YEE Type1 206 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GD 2.09 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 204 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8FA 1.86 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3C Type1 193 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8FB 1.86 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3C Type1 200 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8UWRA 2.04 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi XQX Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3H9RA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi TAK Type1 172 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4C02A 2.17 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 178 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6I1SA 1.52 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi E26 Type1 172 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8EA 1.72 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A29 Type1 193 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8EB 1.72 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A29 Type1 193 - 498 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9RDAA 1.748 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi A1JFB Type1 172 - 498 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8ZA 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3D Type1 203 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8ZB 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3D Type1 193 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNSA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNSB 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6EIXA 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 192 - 503 0 None Q207E Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7BB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH7 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7CB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, T5Y Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7DB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XHD Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7EB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XEA Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7KB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XEJ Type1, Allosteric 205 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7MB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HVK Type1, Allosteric 208 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7NB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 2AI Type1, Allosteric 207 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7SB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 09V Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7VB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH1 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7XB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LGA Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7ZB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, BYZ Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S82B 1.71 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LU8, LAC Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S86B 1.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LU8, XK7 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S87B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKD Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S88B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKS Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8AB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKY Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8PODA 2.59 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 7IO, F Type1, Allosteric 172 - 498 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S75B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HUH, HUH Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S79A 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7AB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, T5V, T5V Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7EA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7FA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7FB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH4, XH4 Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7GA 1.78 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7OA 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7QA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7UA 1.59 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7UB 1.59 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi LU8, XGY, XGY Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7VA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7WA 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7YA 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S80A 1.67 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S80B 1.67 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGM, XGM Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S82A 1.71 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S87A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S88A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S9KA 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SRHB 1.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6Z36A 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi Q5Z, Q5Z, Q5Z Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S77A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, BAQ Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7DA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XHD Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7JA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XHG Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7KA 1.31 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8, XEJ Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7LA 1.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XHJ Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7MA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, HVK, HVK Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7NA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, 2AI Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7PA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, V1L Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7SA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, 09V Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7TB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGJ, XGJ, XGJ Type1, Allosteric, Allosteric, Allosteric 205 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7XA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, LGA Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S86A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK7 Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S89A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XKV Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8AA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XKY Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8BB 1.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XFV, XFV, XFV Type1, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S75A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HUH, HUH Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7AA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, T5V, T5V Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7BA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioi LU8, LU8, LU8, XH7, XH7 Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7HA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HVB, HVB Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7ZA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, BYZ, BYZ Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S81B 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJV, XJV, XJV, XJV Type1, Allosteric, Allosteric, Allosteric, Allosteric 208 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7CA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, T5Y, T5Y, T5Y Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7IA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HV2, HV2, HV2 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7TA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XGJ, XGJ, XGJ Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7YB 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJP, XJP, XJP, XJP, XJP Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 207 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7RB 1.46 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGS, XGS, XGS, XGS, XGS, XGS Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S85A 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK4, XK4, XK4, XK4 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S8BA 1.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XFV, XFV, XFV, XFV Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7RA 1.46 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XGS, XGS, XGS, XGS, XGS Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7IB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HV2, HV2, HV2, HV2, HV2, HV2, HV2, HV2, HV2 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S78A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XGV, XGV, XGV Type1, Allosteric, Allosteric, Allosteric, Allosteric, Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S81A 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XJV, XJV Type1, Allosteric, Allosteric, Allosteric, Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S76A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, 02A, 02A Type1, Allosteric, Allosteric, Allosteric, Type1.5_Back 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7LB 1.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XHJ, XHJ, XHJ, XHJ Type1, Allosteric, Allosteric, Allosteric, Type3 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S84A 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK1 Type1, Allosteric, Allosteric, Type1 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S83A 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XJY Type1, Allosteric, Allosteric, Type3 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7OB 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJJ Type1, Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S85B 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XK4, XK4, XK4 Type1, Type1, Allosteric, Allosteric 207 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S76B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 02A Type1, Type1.5_Back 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S9KB 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, YV4 Type1, Type3 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T6DA 2.56 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1B ACV1B_HUMAN AF-P36896-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 504 0 None None Activin receptor type-1B
TKL ACVR1B ACV1B_HUMAN AF-P36896-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 504 0 None None Activin receptor type-1B
TKL ACVR1C ACV1C_HUMAN AF-Q8NER5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 187 - 492 0 None None Activin receptor type-1C
TKL ACVR1C ACV1C_HUMAN AF-Q8NER5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 187 - 492 0 None None Activin receptor type-1C
TKL ACVR2A AVR2A_HUMAN AF-P27037-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN AF-P27037-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 3SOCA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi GVD Type1 191 - 486 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 3SOCB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GVD Type1 191 - 486 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 4ASXA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6OJ Type1 191 - 486 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 4ASXB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 6OJ Type1 191 - 486 0 None None Activin receptor type-2A
TKL ACVR2B AVR2B_HUMAN AF-Q13705-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B
TKL ACVR2B AVR2B_HUMAN AF-Q13705-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B
TKL ACVR2B AVR2B_HUMAN 2QLUA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 190 - 484 0 None None Activin receptor type-2B
TKL ACVRL1 ACVL1_HUMAN AF-P37023-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 499 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN AF-P37023-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 499 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0A 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0B 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0C 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0D 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 491 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0E 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0F 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0G 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0H 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0I 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0J 2.65 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn LDN Type1 200 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0K 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0L 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0M 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0N 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0O 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 490 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0P 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0Q 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0R 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0S 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0T 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0U 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0V 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0W 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0X 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 488 0 None None Activin receptor type-1-like
TKL AMHR2 AMHR2_HUMAN AF-Q16671-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 515 0 None None Anti-Muellerian hormone type-2 receptor
TKL AMHR2 AMHR2_HUMAN AF-Q16671-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 515 0 None None Anti-Muellerian hormone type-2 receptor
TKL ANKK1 ANKK1_HUMAN AF-Q8NFD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 13 - 295 0 None None Ankyrin repeat and protein kinase domain-containing protein 1
TKL ANKK1 ANKK1_HUMAN AF-Q8NFD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 13 - 295 0 None None Ankyrin repeat and protein kinase domain-containing protein 1
TKL ARAF ARAF_HUMAN AF-P10398-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN AF-P10398-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN 9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
TKL BMPR1A BMR1A_HUMAN AF-P36894-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 226 - 531 0 None None Bone morphogenetic protein receptor type-1A
TKL BMPR1A BMR1A_HUMAN AF-P36894-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 226 - 531 0 None None Bone morphogenetic protein receptor type-1A
TKL BMPR1B BMR1B_HUMAN AF-O00238-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 196 - 501 0 None None Bone morphogenetic protein receptor type-1B
TKL BMPR1B BMR1B_HUMAN AF-O00238-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 196 - 501 0 None None Bone morphogenetic protein receptor type-1B
TKL BMPR1B BMR1B_HUMAN 3MDYA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 502 0 None None Bone morphogenetic protein receptor type-1B
TKL BMPR1B BMR1B_HUMAN 3MDYC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 500 0 None None Bone morphogenetic protein receptor type-1B
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 6UNPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN AF-Q13873-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN AF-Q13873-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PRFA 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9AXXB 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV1B 2.47 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XAGC 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 449 - 732 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XAGD 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo No_ligand No_ligand 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN AF-P15056-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 724 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN AF-P15056-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 724 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9AXXD 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q4CB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEB 2.848 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEC 2.848 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEF 2.848 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEG 2.848 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UANC 3.9 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 449 - 733 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2HC 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 29L Type1 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2HD 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 29L Type1 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4YHTA 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 4EF Type1 449 - 719 0 None I543T,I544N,I551T,L706T,L716T Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4YHTB 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 4EF Type1 449 - 720 0 None I543T,I544N,I551T,L706T,L716T Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 2FB8A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 215 Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 2FB8B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 215 Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3D4QA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nooo SM5 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3D4QB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nooo SM5 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PPKA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno FNI Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PPKB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FNI Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PRIA 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooo FP4 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PRIB 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooo FP4 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PSBA 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno SM6 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PSBB 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM6 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PSDA 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno SM7 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PSDB 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM7 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q4CA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo RSW Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E26A 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 734 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVA 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnio 29L Type1 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFA 2.802 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNFB 2.802 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFFA 3.89 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnoo 215 Type1 449 - 732 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFFB 3.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 215 Type1 449 - 733 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PPJA 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PPJB 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVB 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 29L Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMA 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMD 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2B 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2D 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UANB 3.9 Inactive DFGin‑BLAplus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 449 - 750 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9BFBA 1.92 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo A1AN9 Type1 448 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9BP8A 1.73 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo A1AQY Type1 449 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5FD2B 2.89 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 5XJ Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYUA 4.07 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1AEN Type1 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E26B 2.55 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo 734 Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEC 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIED 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFDA 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7MFEA 4.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 9O2ZA 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYOA 3.74 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV3B 2.8 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FK3B 2.65 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3OG7B 2.45 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UUOA 3.288 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno QH1 Type1 450 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4H58A 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 10Z Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PRFB 2.9 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaiii APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSWA 2.66 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5ITAB 1.95 Inactive DFGin‑None out-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6DC Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2UA 3.78 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MBJA 3.6 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MBJB 3.6 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9RB 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7YA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7YB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno TXV Type2 449 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V34A 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnoo QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V34B 3.15 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4R5YA 3.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4R5YB 3.5 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XFPA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo V1Y Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XLOA 2.493 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo V5J Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XLOB 2.493 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn V5J Type2 450 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VA 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VB 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VC 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno VQP Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VD 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P3DA 2.11 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnoo 0LI Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GC 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GD 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7OA 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iioo QOP Type2 449 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7OB 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo QOP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7PA 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7PB 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo K81 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGA 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGB 3.09 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGC 3.09 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGD 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6CADA 2.55 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NSQA 3.05 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KZP Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7XA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7XB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo TXV Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV9A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo 1OO Type2 448 - 705 0 None R443S,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HI2A 2.512 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIDA 2.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIDB 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWJA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWJB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0PA 2.37 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0PB 2.37 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8QQGB 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8QQGC 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CT7A 3.17 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VALA 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 92D Type2 446 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VALB 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 92D Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VAMA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VAMB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0QA 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno K7S Type2 446 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0QB 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno K7S Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q96A 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0NF Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q96B 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0NF Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNA 3.15 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FC0A 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FC0B 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSPA 2.93 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSPB 2.93 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSQA 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SW Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSQB 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SW Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3IDPA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3IDPB 2.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9RA 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno B1E Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5C9CA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5C9CB 2.7 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWHA 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWHB 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3II5A 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 831 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3II5B 2.79 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 831 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9CA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9CB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GB 2.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo E7M, NHE Type2, Allosteric 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZWA 3.493 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 720 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3C4CB 2.57 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZWB 3.493 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type2 448 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6CADB 2.55 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NSQB 3.05 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno KZP Type2 447 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8QQGA 2.979 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_nnno WJ9 Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CT7B 3.17 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYPC 3.29 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 363 - 733 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYRA 4.32 Inactive None‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 361 - 736 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7ZR0K 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7ZR5K 3.9 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7ZR6K 4.2 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0JA 4.9 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 733 0 SEP729 S365A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0JB 4.9 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 734 0 SEP729 S365A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0TA 5.7 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 732 0 SEP729 S365A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0TB 5.7 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 730 0 SEP729 S365A Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0KA 6.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 737 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0KB 6.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYVC 5.86 Inactive None‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 362 - 733 0 SEP365,SEP729 K601E Serine/threonine-protein kinase B-raf
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3KMUA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 185 - 451 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 6MIBA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 183 - 452 0 None L207W Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5HA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo IRE Type1 182 - 452 0 None C346S,R371Q,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5FA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo DB8 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5GAAAA 1.55 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo A1A2V Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5PA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo AQ4 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5EA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo IRE, IRE Type1, Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL IRAK1 IRAK1_HUMAN AF-P51617-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1
TKL IRAK1 IRAK1_HUMAN AF-P51617-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1
TKL IRAK1 IRAK1_HUMAN 6BFNA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1
TKL IRAK1 IRAK1_HUMAN 6BFNB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK4 IRAK4_HUMAN 2OIDA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDB 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2WA 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2WB 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 163 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2WC 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2WD 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN AF-Q9NWZ3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 167 - 460 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN AF-Q9NWZ3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 167 - 460 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2O8YA 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 459 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2O8YB 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 459 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIBA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIBB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIBC 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OIBD 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3DA 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJT Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3DB 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJT Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3EA 2.67 Inactive DFGin‑BLAminus in-out none-in nonTYR APEdihe_aaiii APEdist_iiii CJQ Type1 164 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3EB 2.67 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJQ Type1 164 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3GA 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CJN Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3GB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CJN Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6N8GA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6N8GB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6N8GC 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6N8GD 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR5AAA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR5BBB 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR5CCC 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR5DDD 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2VA 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2VB 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2VC 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7C2VD 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OICA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OICB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OICC 2.4 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni STU Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2OICD 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4XS2A 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4XS2B 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4XS2C 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4XS2D 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YO6A 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YO6B 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YO6C 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YP8A 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YP8B 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YP8C 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YP8D 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTLA 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTLB 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTLC 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTLD 2.39 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTMA 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTMB 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTMC 2.66 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTMD 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTNA 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTNB 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTNC 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4ZTND 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K72A 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K72B 2.22 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6QY Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K72C 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K72D 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K75A 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K75B 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K75C 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K75D 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K76A 2.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6R1 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K76B 2.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R1 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7GA 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7GB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6R0 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7GC 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7GD 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7IA 2.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QZ Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5K7IB 2.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QZ Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX7B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YD Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX8A 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX8B 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX8C 2.671 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX8D 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1SA 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1SC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1SD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TA 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TB 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TC 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1TD 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4Y73A 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4Y73B 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4Y73C 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4Y73D 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6MOMA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6MOMB 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6MOMC 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 163 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6MOMD 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA2A 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW0 Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA2B 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW0 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWX Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA3H0A0 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWX Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA4A 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA4B 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA4C 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA4D 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA5A 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA5B 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA5C 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA5D 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA6A 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA6B 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA6C 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA6D 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UB 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 160 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UC 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O8UD 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 162 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5W84A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9YY Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5W84B 2.9 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 9YY Type1 168 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5W85A 2.25 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9YS Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5W85B 2.25 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9YS Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYA 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYB 2.19 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYD 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 162 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYE 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6VQLA 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6VQLB 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6VQLC 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6VQLD 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCEA 1.89 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCEB 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCED 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCEE 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCVA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVG Type1 163 - 458 0 SEP284,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCVB 2.69 Inactive DFGin‑BLAminus in-none none-out nonTYR APEdihe_aannn APEdist_ooon ZVG Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCWA 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCWB 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCWC 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8SCWD 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRUA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRUB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRUC 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRUD 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRYC 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRYD 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 460 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4RMZA 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T20 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4RMZB 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T20 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVMA 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVMB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVMC 2.1 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 160 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVNA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 167 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVNB 1.95 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVNC 1.95 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TX0A 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VEU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TX0B 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VEU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBA 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBB 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBC 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBD 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCCA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii WFQ Type1 160 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCCB 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii WFQ Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THWA 2.44 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii NBK Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THWB 2.44 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii NBK Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THXA 1.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii N9Z Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THXB 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N9Z Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THZA 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NB5 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6THZB 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NB5 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TI8A 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TI8B 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TI8C 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TI8D 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG2A 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG2B 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG2C 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG2D 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG3A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4U Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG3B 2.11 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B4U Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG5A 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7R Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG5B 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7R Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9GA 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9GB 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9GC 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9GD 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JA 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 161 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JB 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 161 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JC 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JD 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9KA 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 162 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9KB 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 158 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9KD 1.87 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94A 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94B 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94C 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94D 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O95A 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O95B 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O95C 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O95D 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DA 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DB 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DC 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DD 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6UYAA 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6UYAB 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6UYAC 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6UYAD 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3IA 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CKN Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3IB 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CKN Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFIA 2.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1H Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFIB 2.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1H Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFJA 2.61 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1E Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFJB 2.61 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1E Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG1A 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B8I Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG1B 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B8I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQA 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQB 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQC 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIQD 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIRA 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BY Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIRB 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UISA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UISB 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UISC 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 162 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UISD 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UITA 1.84 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CD Type1 162 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UITB 1.84 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CD Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIUA 2.02 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIUB 2.02 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3WA 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 162 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3WB 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3WC 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3WD 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3XA 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 162 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3XB 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3XC 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8W3XD 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OA 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OB 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OC 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OD 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2FA 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2FB 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2FC 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 160 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2FD 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LA 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LB 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LC 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LD 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATBAAA 2.35 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O0H Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATBBBB 2.35 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O0H Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATLAAA 2.464 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O6X Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATLBBB 2.464 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O6X Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATNAAA 2.171 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O06 Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATNBBB 2.171 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O06 Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR6AAA 2.167 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6I Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR6BBB 2.167 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6I Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR7AAA 2.119 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6R Type1 165 - 458 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR7BBB 2.119 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6R Type1 165 - 458 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8DKSA 2.45 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii SO9 Type1 165 - 459 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8DKSB 2.45 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii SO9 Type1 164 - 459 0 SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8WTFA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGDA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGDD 2.1 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGEA 1.401 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 165 - 459 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGED 1.401 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn DL1 Type1 164 - 457 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U9AA 2.8 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4YO6D 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD, 4GD Type1, Allosteric 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TIAA 2.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ND2, ND2, ND2, ND2 Type1, Allosteric, Allosteric, Allosteric 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6TIAB 2.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ND2, ND2, ND2, ND2 Type1, Allosteric, Allosteric, Allosteric 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5T1SB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1.5_Back 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9KC 1.87 Inactive DFGin‑BLAplus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A1JDQ Type1 164 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRYA 2.15 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRYB 2.15 Inactive DFGin‑BLBminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGFB 2.61 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 164 - 460 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVMD 2.1 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnni VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U97B 2.65 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U9AB 2.8 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EG9A 2.414 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni 0LI Type2 164 - 459 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EG9B 2.414 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 0LI Type2 165 - 459 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGAA 2.512 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoio APEdist_nnni J8A Type2 166 - 459 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6EGAB 2.512 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aaiii APEdist_nnni J8A Type2 164 - 459 0 None None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX7A 2.8 Inactive None‑None none-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 192 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8TVND 1.95 Inactive None‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN AF-P53667-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN AF-P53667-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVJB 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiai APEdist_niii No_ligand No_ligand 330 - 637 0 None D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 3S95A 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 3S95B 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5NXCL 2.25 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiai APEdist_nnno 9DB Type1 330 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN AF-P53671-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN AF-P53671-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 334 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 331 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_oooo T3B Type2 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoao APEdist_iooo T3B Type2 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 5NXDA 1.9 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2
TKL LRRK1 LRRK1_HUMAN AF-Q38SD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1230 - 1530 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN AF-Q38SD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1230 - 1530 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN 8E04A 3.8 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 381 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN 8E05A 4.6 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN 8E05B 4.6 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN 8E06A 4.3 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK1 LRRK1_HUMAN 8FACA 3.92 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 341 - 2013 0 None None Leucine-rich repeat serine/threonine-protein kinase 1
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1867 - 2142 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1867 - 2142 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TXZA 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8SMCC 4.02 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii TVT Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U7HC 3.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0T Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO7C 3.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZGA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP8A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VNOA 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP6A 3.47 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 6VP7A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZHA 3.9 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 627 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 9CHOA 7.8 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 543 - 2527 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHTA 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHTB 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LHWA 3.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 540 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LI4A 3.1 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO2E 4.13 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO8C 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO8E 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9F 3.48 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH5A 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH5C 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 7LI3A 3.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 9CI3A 3.96 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 907 - 2527 0 SEP910,SEP935 None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZBA 3.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U7LA 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U7LB 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8AB 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8AC 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8BA 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8BB 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TYQA 2.99 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1335 - 2525 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9E 3.48 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 9DMIA 3.35 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnoi A1A7Q Type2 1334 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZEA 2.9 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1624 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZFA 3.4 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 587 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8VH4A 4.1 Inactive None‑None out-none out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U1BA 3.7 Inactive None‑None none-none none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1952 - 2521 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL MAP3K10 M3K10_HUMAN AF-Q02779-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 90 - 367 0 None None Mitogen-activated protein kinase kinase kinase 10
TKL MAP3K10 M3K10_HUMAN AF-Q02779-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 90 - 367 0 None None Mitogen-activated protein kinase kinase kinase 10
TKL MAP3K11 M3K11_HUMAN AF-Q16584-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11
TKL MAP3K11 M3K11_HUMAN AF-Q16584-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CENA 1.7 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaooi APEdist_iioo No_ligand No_ligand 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CEOA 2.28 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50D Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CEPA 1.99 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50E Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5CEQA 1.911 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50F Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5VO1A 2.45 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FS Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 5VO2A 2.96 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FV Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OURA 1.95 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W38 Type1 118 - 396 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OUSA 2.2 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3I Type1 118 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8OUTA 1.935 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3C Type1 118 - 399 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 9CDYA 1.5 Inactive DFGin‑BLBplus out-na out-out nonTYR APEdihe_aaooi APEdist_nnoo A1AZ8 Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 8DEGA 2.79 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno SIQ Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN 9CDXA 2.38 Inactive DFGin‑None out-na none-out nonTYR APEdihe_aaooi APEdist_nnno A1AZP Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K13 M3K13_HUMAN AF-O43283-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 160 - 417 0 None None Mitogen-activated protein kinase kinase kinase 13
TKL MAP3K13 M3K13_HUMAN AF-O43283-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 160 - 417 0 None None Mitogen-activated protein kinase kinase kinase 13
TKL MAP3K20 M3K20_HUMAN AF-Q9NYL2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 270 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN AF-Q9NYL2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 270 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5HESB 2.14 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 032 Type1 7 - 298 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWB 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWC 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K21 M3K21_HUMAN AF-Q5TCX8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 116 - 408 0 None None Mitogen-activated protein kinase kinase kinase 21
TKL MAP3K21 M3K21_HUMAN AF-Q5TCX8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 116 - 408 0 None None Mitogen-activated protein kinase kinase kinase 21
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21
TKL MAP3K7 M3K7_HUMAN AF-O43318-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 294 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN AF-O43318-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 294 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5V5NA 2.006 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno EDH Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 7NTHA 1.97 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno URW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 7NTIA 1.98 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno UWZ Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JGAA 2.0 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6KC Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JGDA 3.101 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6KD Type1 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 9FPDA 2.402 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_iiii A1IED Type1 31 - 496 0 TPO187,SEP192 None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 2EVAA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ADN Type1 31 - 305 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4L3PA 2.68 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 1UH Type1 31 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JGBA 2.8 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno 6JV Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4L52A 2.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1UL Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4L53A 2.55 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1UO Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3A 2.05 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 27 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JH6A 2.365 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno T92 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5GJGA 2.61 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6V5 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3B 2.05 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 27 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3C 2.05 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 25 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3D 2.05 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 27 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5E7RA 2.11 Inactive DFGout‑BBAminus none-none none-out nonTYR APEdihe_aaooi APEdist_nnno 5KW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 2YIYA 2.49 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno YIY Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4O91A 2.393 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno NG2 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5GJDA 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno 6V3 Type2 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5J9LA 2.752 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6HF Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5J7SA 2.368 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6H3 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5GJFA 2.89 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaooi APEdist_iiio 6V4 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5J8IA 2.404 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6H4 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JK3A 2.371 Inactive None‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6L4 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K9 M3K9_HUMAN AF-P80192-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 136 - 413 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN AF-P80192-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 136 - 413 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN 4UY9A 2.81 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 135 - 447 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN 4UY9B 2.81 Inactive DFGin‑BLBplus in-none out-out nonTYR APEdihe_aaoni APEdist_oooo No_ligand No_ligand 135 - 449 0 None None Mitogen-activated protein kinase kinase kinase 9
TKL MAP3K9 M3K9_HUMAN 3DTCA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaini APEdist_nnno VIN Type1 136 - 405 0 None T312A Mitogen-activated protein kinase kinase kinase 9
TKL RAF1 RAF1_HUMAN AF-P04049-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 341 - 616 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN AF-P04049-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 341 - 616 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AYAA 2.59 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 342 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AYAC 2.59 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AXAA 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AXAC 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AXCA 4.16 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AXCC 4.16 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UG 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VG 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 3OMVB 4.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_nooo SM5 Type1 340 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UC 2.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VC 3.5 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CPDA 3.46 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CPDB 3.46 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 3OMVA 4.0 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM5 Type1 340 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CHFA 4.25 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio 29L Type1 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8CHFB 4.25 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio 29L Type1 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8GFTD 3.8 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 404 - 611 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8U1LC 3.7 Inactive None‑None none-none none-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 418 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 7Z37CP1 3.67 Inactive None‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 406 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 7Z38C 3.16 Inactive None‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 406 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 8GAED 3.3 Inactive None‑None none-na none-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 404 - 610 0 None None RAF proto-oncogene serine/threonine-protein kinase
TKL RIPK1 RIPK1_HUMAN AF-Q13546-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 295 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN AF-Q13546-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 295 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q31B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno TME, A1CNU Allosteric, Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZZA 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU5 Type1 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C3EB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type1 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7XMKA 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno GO4 Type1 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7XMKB 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn GO4 Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7YDXB 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 8I2NA 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5HX6B 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 65U Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5TX5B 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 7MJ Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6OCQA 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6RLNB 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn K8K Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IPG, RCM Type1, Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7YDXA 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 8I2NB 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FD0A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 3IU Type2 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FD0B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 3IU Type2 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4NEUA 2.57 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aaiii APEdist_nnni Q1A Type2 6 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4NEUB 2.57 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn Q1A Type2 7 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IPG Type3, Type1 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYB 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IKX Type3, Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK2 RIPK2_HUMAN 5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN AF-O43353-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN AF-O43353-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8AZAA 3.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8AZAB 3.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR2A 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR2B 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OA 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OB 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OC 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OD 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OE 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OF 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OG 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OH 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OI 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OJ 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OK 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OL 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OM 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5ON 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OO 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5OP 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6HMXA 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6HMXB 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZEB 2.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZJB 2.53 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nioo M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6FU5A 3.26 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6S1FB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6S1FD 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR5A 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR5B 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J79A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GE Type1 2 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J79B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 6GE Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG2A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG2B 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6UL8A 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6UL8B 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RN8A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RN8B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RNAA 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RNAB 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8X2OA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8X2OB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5JA 2.85 Inactive DFGin‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5W5JB 2.85 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 10 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6FU5B 3.26 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 9F3VA 1.943 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 9F3VB 1.943 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR8A 2.79 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 4C8BA 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoni APEdist_nnno 0LI Type2 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 4C8BB 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 0LI Type2 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR7A 2.71 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK3 RIPK3_HUMAN AF-Q9Y572-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN AF-Q9Y572-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3B 3.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1 12 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK4 RIPK4_HUMAN AF-P57078-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 4
TKL RIPK4 RIPK4_HUMAN AF-P57078-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 4
TKL TESK1 TESK1_HUMAN AF-Q15569-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 46 - 321 0 None None Dual specificity testis-specific protein kinase 1
TKL TESK1 TESK1_HUMAN AF-Q15569-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 46 - 321 0 None None Dual specificity testis-specific protein kinase 1
TKL TESK2 TESK2_HUMAN AF-Q96S53-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 319 0 None None Dual specificity testis-specific protein kinase 2
TKL TESK2 TESK2_HUMAN AF-Q96S53-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 319 0 None None Dual specificity testis-specific protein kinase 2
TKL TGFBR1 TGFR1_HUMAN 5E8UA 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 502 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2NA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E8SA 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN AF-P36897-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 197 - 502 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN AF-P36897-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 197 - 502 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E8TA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 499 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1B6CB 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1B6CD 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1B6CF 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1B6CH 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASE 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E8XA 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 200 - 503 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E90A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 200 - 499 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5USQA 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8LY Type1 200 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1RW8A 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 580 Type1 200 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5FRIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZUQ Type1 200 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1VJYA 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii 460 Type1 201 - 503 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3GXLA 1.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii QIG Type1 201 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3HMMA 1.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 855 Type1 201 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 9F6XA 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IAZ Type1 200 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X0MA 1.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WA Type1 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2FA 1.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WJ Type1 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2GA 1.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WK Type1 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 9J9DA 1.337 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii A1L30 Type1 202 - 502 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2WOTA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZZG Type1 200 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2WOUA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZZF Type1 200 - 496 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 8YHLA 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D6I Type1 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E8WA 1.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 200 - 501 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5E8ZA 1.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 200 - 499 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QIKA 1.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2M Type1 200 - 499 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QILA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2V Type1 200 - 499 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QTZA 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QMY Type1 200 - 499 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QU0A 1.67 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QMV Type1 200 - 502 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3TZMA 1.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii 085 Type1 200 - 496 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1PY5A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi PY1 Type1 200 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OA 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OB 3.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAA 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAB 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAC 3.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAD 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAE 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 8YHFA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D6I Type1 201 - 498 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2JA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WN Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2KA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WO Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QIMA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2Y Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 6B8YA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D0A Type1.5_Back 200 - 502 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OC 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OD 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OE 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFE 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR2 TGFR2_HUMAN 5E8YA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN AF-P37173-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 236 - 548 0 None None TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN AF-P37173-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 236 - 548 0 None None TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 8YGZA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 240 - 541 0 None None TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 5E8VA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 5E91A 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 5QINA 1.57 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii J2V Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TGFBR2 TGFR2_HUMAN 7DV6A 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HJF Type1 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TKL TNNI3K TNI3K_HUMAN AF-Q59H18-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN AF-Q59H18-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFFA 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFFB 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFFC 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo 4CV Type1 452 - 725 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFFD 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CV Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 6B5JA 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 6B5JB 2.97 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 6B5JC 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo CV4 Type1 451 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 6B5JD 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno CV4 Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFIA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFIB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFIC 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 4YFID 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K

TKL / All / All

Total number of chains: 1297
Active chains: 242
Total number of genes: 59
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 791 61.0% AF-Q04771-K1A
DFGout BBAminus 171 13.2% 8C7YA
DFGin BLBplus 98 7.6% 7M0XA
DFGin BLAplus 55 4.2% 9BP8A
DFGin None 46 3.5% 8GW3A
DFGout None 33 2.5% 8FO9E
None None 33 2.5% 6Q0JA
DFGin BLBminus 29 2.2% 5CENA
DFGinter None 25 1.9% 9D5IA
DFGin ABAminus 13 1.0% 3TL8A
DFGin BLBtrans 3 0.2% 9GFZA
All chains
No PyMOL session because the query has >1000 chains
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Representatives
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All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL BAK1 BAK1_ARATH 3TL8A 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 273 - 576 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8D 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 583 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8H 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 580 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3UIMA 2.2 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii ANP ATPlike 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3ULZA 2.6 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8G 2.5 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 578 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BIK1 BIK1_ARATH 5TOSA 2.35 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 52 - 360 0 SEP253 None Serine/threonine-protein kinase BIK1 Arabidopsis thaliana
TKL BIK1 BIK1_ARATH 5TOSB 2.35 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 52 - 360 0 SEP253 None Serine/threonine-protein kinase BIK1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPWA 2.431 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 866 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6A 1.898 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6B 1.898 Inactive DFGin‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3PPZB 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 540 - 810 0 TPO704,SEP707,SEP710 None Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3PPZA 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 540 - 810 0 TPO704,SEP707,SEP710 None Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3P86B 2.496 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 543 - 810 0 None D676N Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3P86A 2.496 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 544 - 810 0 None D676N Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXA 2.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYA 2.28 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYB 2.28 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVA 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVB 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWA 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWB 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 9UBIA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo OT5 Type1 521 - 818 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 9UBIB 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni OT5 Type1 521 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TA 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TD 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TI 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TJ 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TM 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5UC 3.9 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 172 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5VC 4.25 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 172 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J6IA 3.7 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SYMRK E6YC17_ARAHY 6M0UA 2.29 Inactive DFGin‑BLAplus out-na none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 582 - 881 0 None K625E Nodulation receptor kinase Arachis hypogaea
TKL ROCO4 ROCO4_DICDI 4YZMB 3.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiai APEdist_nioo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F0FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1OA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1MA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP, BTB ATPlike, Allosteric 1019 - 1292 0 None G1179S Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4YZMA 3.0 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoai APEdist_nnoo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4YZNA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_iioo 4K5 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1TA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo H52, H52 Type1, Allosteric 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F0GA 2.0 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL KSR Q24171_DROME 8BW9D 3.32 Inactive None‑None none-none out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 731 - 947 0 None None AT08303p Drosophila melanogaster
TKL ACVR1 ACVR1_HUMAN 6T6DB 2.56 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MM8 Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T6DC 2.56 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 205 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCA 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCB 2.67 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii H8H Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCC 2.67 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi H8H Type1 201 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCD 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNQA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 206 - 496 0 None K493A Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNRA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi ANP ATPlike 208 - 496 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6SZMA 1.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi M2Z, M2Z, M2Z Allosteric, Allosteric, Type1 202 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7QB 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi XJM, LU8, XJM Allosteric, Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN AF-Q04771-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 505 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN AF-Q04771-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 505 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6JUXA 1.75 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi C9U Type1 203 - 499 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4DYMA 2.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IYZ Type1 207 - 499 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ACRA 2.01 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 9TO Type1 203 - 498 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ACRB 2.01 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 9TO Type1 203 - 498 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 7C3GA 1.802 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi FH0 Type1 203 - 499 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 7C3GB 1.802 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi FH0 Type1 204 - 499 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9L04A 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A1L4C Type1 203 - 499 0 None R206H Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3MTFA 2.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3MTFB 2.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3OOMA 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 507 Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UA 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UB 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UC 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UD 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4BGGA 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4BGGB 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4BGGC 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 204 - 497 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4BGGD 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 844 Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OXGA 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OXGB 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OXGC 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OXGD 2.13 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4B Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OY6A 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OY6B 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OY6C 2.56 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5OY6D 2.56 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi B4E Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S77B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S78B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S79B 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7GB 1.78 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8 Type1 207 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7HB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7JB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 206 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7PB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 208 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7WB 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S83B 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S84B 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 206 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S89B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6GI6A 1.98 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi EZB Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6GINA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IR2 Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6GINB 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IR2 Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6GIPA 2.17 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi EUN Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6SRHA 1.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8 Type1 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6SZMB 1.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi M2Z Type1 205 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T6DD 2.56 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii MM8 Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T8NA 1.77 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MVE Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T8NB 1.77 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MVE Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6TN8A 1.63 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 5U6 Type1 204 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6Z36B 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi Q5Z Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 7A21A 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QWQ Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 7A21B 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QWQ Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 7NNSB 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi C87 Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8C7WA 2.26 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi U0C Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8C7ZA 2.23 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi TZX Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8R7GA 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8R7GB 2.09 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 205 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8R7GC 2.09 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii YEE Type1 206 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8R7GD 2.09 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi YEE Type1 204 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8FA 1.86 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3C Type1 193 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8FB 1.86 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3C Type1 200 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8UWRA 2.04 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi XQX Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3H9RA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi TAK Type1 172 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4C02A 2.17 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 178 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6I1SA 1.52 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi E26 Type1 172 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8EA 1.72 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A29 Type1 193 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8EB 1.72 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A29 Type1 193 - 498 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9RDAA 1.748 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi A1JFB Type1 172 - 498 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8ZA 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3D Type1 203 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 9D8ZB 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3D Type1 193 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNSA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNSB 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6EIXA 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi A3F Type1 192 - 503 0 None Q207E Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7BB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH7 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7CB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, T5Y Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7DB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XHD Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7EB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XEA Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7KB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XEJ Type1, Allosteric 205 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7MB 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HVK Type1, Allosteric 208 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7NB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 2AI Type1, Allosteric 207 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7SB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 09V Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7VB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH1 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7XB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LGA Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7ZB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, BYZ Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S82B 1.71 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LU8, LAC Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S86B 1.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LU8, XK7 Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S87B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKD Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S88B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKS Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S8AB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XKY Type1, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 8PODA 2.59 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi 7IO, F Type1, Allosteric 172 - 498 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S75B 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HUH, HUH Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S79A 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7AB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, T5V, T5V Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7EA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7FA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7FB 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XH4, XH4 Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7GA 1.78 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7OA 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7QA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7UA 1.59 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7UB 1.59 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi LU8, XGY, XGY Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7VA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7WA 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7YA 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S80A 1.67 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S80B 1.67 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGM, XGM Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S82A 1.71 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S87A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S88A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S9KA 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6SRHB 1.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8 Type1, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6Z36A 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi Q5Z, Q5Z, Q5Z Type1, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S77A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, BAQ Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7DA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XHD Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7JA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XHG Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7KA 1.31 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii LU8, LU8, LU8, XEJ Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7LA 1.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XHJ Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7MA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, HVK, HVK Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7NA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, 2AI Type1, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7PA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, V1L Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7SA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, 09V Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7TB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGJ, XGJ, XGJ Type1, Allosteric, Allosteric, Allosteric 205 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7XA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, LGA Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S86A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK7 Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S89A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XKV Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S8AA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XKY Type1, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S8BB 1.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XFV, XFV, XFV Type1, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S75A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HUH, HUH Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7AA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, T5V, T5V Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7BA 1.32 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioi LU8, LU8, LU8, XH7, XH7 Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7HA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HVB, HVB Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7ZA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, BYZ, BYZ Type1, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S81B 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJV, XJV, XJV, XJV Type1, Allosteric, Allosteric, Allosteric, Allosteric 208 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7CA 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, T5Y, T5Y, T5Y Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7IA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HV2, HV2, HV2 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7TA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XGJ, XGJ, XGJ Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7YB 1.37 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJP, XJP, XJP, XJP, XJP Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 207 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7RB 1.46 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XGS, XGS, XGS, XGS, XGS, XGS Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S85A 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK4, XK4, XK4, XK4 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S8BA 1.64 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XFV, XFV, XFV, XFV Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7RA 1.46 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XGS, XGS, XGS, XGS, XGS Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7IB 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, HV2, HV2, HV2, HV2, HV2, HV2, HV2, HV2, HV2 Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S78A 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, LU8, LU8, XGV, XGV, XGV Type1, Allosteric, Allosteric, Allosteric, Allosteric, Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S81A 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XJV, XJV Type1, Allosteric, Allosteric, Allosteric, Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S76A 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, 02A, 02A Type1, Allosteric, Allosteric, Allosteric, Type1.5_Back 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7LB 1.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XHJ, XHJ, XHJ, XHJ Type1, Allosteric, Allosteric, Allosteric, Type3 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S84A 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XK1 Type1, Allosteric, Allosteric, Type1 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S83A 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, XJY Type1, Allosteric, Allosteric, Type3 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7OB 1.43 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XJJ Type1, Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S85B 1.33 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, XK4, XK4, XK4 Type1, Type1, Allosteric, Allosteric 207 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S76B 1.31 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, 02A Type1, Type1.5_Back 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S9KB 1.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU8, YV4 Type1, Type3 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T6DA 2.56 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1B ACV1B_HUMAN AF-P36896-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 504 0 None None Activin receptor type-1B Homo sapiens
TKL ACVR1B ACV1B_HUMAN AF-P36896-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 504 0 None None Activin receptor type-1B Homo sapiens
TKL ACVR1C ACV1C_HUMAN AF-Q8NER5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 187 - 492 0 None None Activin receptor type-1C Homo sapiens
TKL ACVR1C ACV1C_HUMAN AF-Q8NER5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 187 - 492 0 None None Activin receptor type-1C Homo sapiens
TKL ACVR2A AVR2A_HUMAN AF-P27037-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN AF-P27037-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3SOCA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi GVD Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3SOCB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GVD Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 4ASXA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6OJ Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 4ASXB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 6OJ Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2B AVR2B_HUMAN AF-Q13705-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B Homo sapiens
TKL ACVR2B AVR2B_HUMAN AF-Q13705-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B Homo sapiens
TKL ACVR2B AVR2B_HUMAN 2QLUA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 190 - 484 0 None None Activin receptor type-2B Homo sapiens
TKL ACVRL1 ACVL1_HUMAN AF-P37023-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 499 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN AF-P37023-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 499 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0A 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0B 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0C 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0D 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 491 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0E 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0F 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0G 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0H 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0I 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0J 2.65 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn LDN Type1 200 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0K 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0L 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0M 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0N 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0O 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 490 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0P 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0Q 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0R 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0S 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0T 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0U 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0V 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0W 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0X 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 488 0 None None Activin receptor type-1-like Homo sapiens
TKL AMHR2 AMHR2_HUMAN AF-Q16671-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 515 0 None None Anti-Muellerian hormone type-2 receptor Homo sapiens
TKL AMHR2 AMHR2_HUMAN AF-Q16671-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 515 0 None None Anti-Muellerian hormone type-2 receptor Homo sapiens
TKL ANKK1 ANKK1_HUMAN AF-Q8NFD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 13 - 295 0 None None Ankyrin repeat and protein kinase domain-containing protein 1 Homo sapiens
TKL ANKK1 ANKK1_HUMAN AF-Q8NFD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 13 - 295 0 None None Ankyrin repeat and protein kinase domain-containing protein 1 Homo sapiens
TKL ARAF ARAF_HUMAN AF-P10398-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf Homo sapiens
TKL ARAF ARAF_HUMAN AF-P10398-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
TKL ARAF ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
TKL BMPR1A BMR1A_HUMAN AF-P36894-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 226 - 531 0 None None Bone morphogenetic protein receptor type-1A Homo sapiens
TKL BMPR1A BMR1A_HUMAN AF-P36894-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 226 - 531 0 None None Bone morphogenetic protein receptor type-1A Homo sapiens
TKL BMPR1B BMR1B_HUMAN AF-O00238-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 196 - 501 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens
TKL BMPR1B BMR1B_HUMAN AF-O00238-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 196 - 501 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens
TKL BMPR1B BMR1B_HUMAN 3MDYA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 502 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens
TKL BMPR1B BMR1B_HUMAN 3MDYC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 500 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 6UNPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii ADP, ADP ATPlike, Allosteric 199 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN AF-Q13873-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN AF-Q13873-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 195 - 511 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PRFA 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9AXXB 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV1B 2.47 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XAGC 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 449 - 732 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XAGD 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo No_ligand No_ligand 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN AF-P15056-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 724 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN AF-P15056-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 724 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9AXXD 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q4CB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNEB 2.848 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNEC 2.848 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNEF 2.848 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNEG 2.848 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UANC 3.9 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 449 - 733 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6U2HC 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 29L Type1 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6U2HD 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 29L Type1 448 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4YHTA 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 4EF Type1 449 - 719 0 None I543T,I544N,I551T,L706T,L716T Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4YHTB 3.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno 4EF Type1 449 - 720 0 None I543T,I544N,I551T,L706T,L716T Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 2FB8A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi 215 Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 2FB8B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 215 Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3D4QA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nooo SM5 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3D4QB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_nooo SM5 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PPKA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno FNI Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PPKB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FNI Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PRIA 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooo FP4 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PRIB 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooo FP4 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PSBA 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno SM6 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PSBB 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM6 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PSDA 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno SM7 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PSDB 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM7 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q4CA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo RSW Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E26A 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 734 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7SHVA 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnio 29L Type1 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNFA 2.802 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MNFB 2.802 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 29L Type1 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFFA 3.89 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnoo 215 Type1 449 - 732 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFFB 3.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 215 Type1 449 - 733 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PPJA 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PPJB 3.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7SHVB 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 29L Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMA 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMD 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2B 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2D 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UANB 3.9 Inactive DFGin‑BLAplus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 449 - 750 0 SEP729 T373C,I374M Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9BFBA 1.92 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo A1AN9 Type1 448 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9BP8A 1.73 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo A1AQY Type1 449 - 721 0 None F667A,R671A,Y673A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5FD2B 2.89 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 5XJ Type1 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3SKCB 3.2 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYUA 4.07 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1AEN Type1 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E26B 2.55 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo 734 Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEC 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIED 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9AXYA 3.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6PP9A 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2WA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0TA 3.19 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_iooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0UA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0VA 3.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0WA 3.09 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0XA 2.47 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0YA 3.45 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ANP ATPlike 447 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7M0ZA 3.12 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo ANP ATPlike 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9ECUA 3.46 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 447 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6U2GB 2.886 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo ACP ATPlike 451 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NYBA 4.1 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 233 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGSA 4.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 155 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8DGTA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo AGS ATPlike 151 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFDA 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7MFEA 4.07 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 9O2ZA 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 156 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYOA 3.74 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 235 - 738 0 SEP365,SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV3B 2.8 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FK3B 2.65 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3OG7B 2.45 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UUOA 3.288 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno QH1 Type1 450 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4H58A 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 10Z Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PRFB 2.9 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaiii APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSWA 2.66 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5ITAB 1.95 Inactive DFGin‑None out-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6DC Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2UA 3.78 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MBJA 3.6 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MBJB 3.6 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9RB 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7YA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7YB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno TXV Type2 449 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V34A 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnoo QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V34B 3.15 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4R5YA 3.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4R5YB 3.5 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XFPA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo V1Y Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XLOA 2.493 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo V5J Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XLOB 2.493 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn V5J Type2 450 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VA 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VB 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VC 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno VQP Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VD 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P3DA 2.11 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnoo 0LI Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GC 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GD 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7OA 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iioo QOP Type2 449 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7OB 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo QOP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7PA 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7PB 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo K81 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGA 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGB 3.09 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGC 3.09 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGD 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6CADA 2.55 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NSQA 3.05 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KZP Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7XA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7XB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo TXV Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV9A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo 1OO Type2 448 - 705 0 None R443S,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HI2A 2.512 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIDA 2.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIDB 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWJA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWJB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0PA 2.37 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0PB 2.37 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8QQGB 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8QQGC 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CT7A 3.17 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VALA 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 92D Type2 446 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VALB 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 92D Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VAMA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VAMB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0QA 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno K7S Type2 446 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0QB 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno K7S Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q96A 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0NF Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q96B 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0NF Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4DBNA 3.15 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4DBNB 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FC0A 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FC0B 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSPA 2.93 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSPB 2.93 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSQA 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SW Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSQB 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SW Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3IDPA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3IDPB 2.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9RA 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno B1E Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5C9CA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5C9CB 2.7 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWHA 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWHB 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3II5A 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 831 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3II5B 2.79 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 831 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9CA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9CB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GB 2.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo E7M, NHE Type2, Allosteric 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZWA 3.493 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 720 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3C4CB 2.57 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZWB 3.493 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type2 448 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6CADB 2.55 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NSQB 3.05 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno KZP Type2 447 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8QQGA 2.979 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_nnno WJ9 Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CT7B 3.17 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYPC 3.29 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 363 - 733 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYRA 4.32 Inactive None‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 361 - 736 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7ZR0K 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7ZR5K 3.9 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7ZR6K 4.2 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 521 - 724 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0JA 4.9 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 733 0 SEP729 S365A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0JB 4.9 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 734 0 SEP729 S365A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0TA 5.7 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 732 0 SEP729 S365A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0TB 5.7 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 730 0 SEP729 S365A Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0KA 6.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 737 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6Q0KB 6.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_iioi No_ligand No_ligand 449 - 733 0 SEP729 None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYVC 5.86 Inactive None‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 362 - 733 0 SEP365,SEP729 K601E Serine/threonine-protein kinase B-raf Homo sapiens
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3KMUA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 185 - 451 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 6MIBA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 183 - 452 0 None L207W Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5HA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo IRE Type1 182 - 452 0 None C346S,R371Q,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5FA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo DB8 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5GAAAA 1.55 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo A1A2V Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5PA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo AQ4 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5EA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo IRE, IRE Type1, Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL IRAK1 IRAK1_HUMAN AF-P51617-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
TKL IRAK1 IRAK1_HUMAN AF-P51617-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 199 - 528 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
TKL IRAK1 IRAK1_HUMAN 6BFNA 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
TKL IRAK1 IRAK1_HUMAN 6BFNB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 194 - 526 0 None None Interleukin-1 receptor-associated kinase 1 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDA 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDB 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2WA 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2WB 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 163 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2WC 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2WD 3.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YTH, FJ9 Allosteric, Type1 164 - 458 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN AF-Q9NWZ3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 167 - 460 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN AF-Q9NWZ3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 167 - 460 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2O8YA 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 459 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2O8YB 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 459 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIBA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIBB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIBC 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIBD 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3DA 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJT Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3DB 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJT Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3EA 2.67 Inactive DFGin‑BLAminus in-out none-in nonTYR APEdihe_aaiii APEdist_iiii CJQ Type1 164 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3EB 2.67 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CJQ Type1 164 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3GA 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CJN Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3GB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CJN Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6N8GA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6N8GB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6N8GC 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6N8GD 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KFD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR5AAA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR5BBB 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR5CCC 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR5DDD 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R73 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2VA 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2VB 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2VC 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7C2VD 2.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FJ0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OICA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OICB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OICC 2.4 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni STU Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OICD 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4XS2A 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4XS2B 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4XS2C 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4XS2D 2.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 42P Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YO6A 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YO6B 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YO6C 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YP8A 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YP8B 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YP8C 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YP8D 2.641 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GF Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTLA 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTLB 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTLC 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTLD 2.39 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S1 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTMA 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTMB 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTMC 2.66 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTMD 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S2 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTNA 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTNB 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTNC 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4ZTND 2.23 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4S3 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K72A 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K72B 2.22 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6QY Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K72C 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K72D 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QY Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K75A 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K75B 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K75C 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K75D 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6QX Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K76A 2.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6R1 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K76B 2.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R1 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7GA 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7GB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii 6R0 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7GC 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7GD 2.23 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6R0 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7IA 2.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QZ Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5K7IB 2.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QZ Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX7B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YD Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX8A 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX8B 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX8C 2.671 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX8D 2.671 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6YE Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1SA 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1SC 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1SD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1TA 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1TB 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1TC 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1TD 2.34 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76P Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4Y73A 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4Y73B 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4Y73C 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4Y73D 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XPY Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6MOMA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6MOMB 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6MOMC 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 163 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6MOMD 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii JX4 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA2A 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW0 Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA2B 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW0 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWX Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA3H0A0 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWX Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA4A 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA4B 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA4C 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA4D 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW1 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA5A 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA5B 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA5C 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA5D 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA6A 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA6B 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 166 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA6C 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9NA6D 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BWZ Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O8UA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O8UB 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 160 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O8UC 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O8UD 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LS7 Type1 162 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5W84A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9YY Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5W84B 2.9 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 9YY Type1 168 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5W85A 2.25 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9YS Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5W85B 2.25 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9YS Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6LXYA 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6LXYB 2.19 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6LXYD 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 162 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6LXYE 2.19 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii EXF Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6VQLA 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6VQLB 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6VQLC 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6VQLD 2.069 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R7S Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCEA 1.89 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCEB 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCED 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCEE 1.89 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVD Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCVA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVG Type1 163 - 458 0 SEP284,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCVB 2.69 Inactive DFGin‑BLAminus in-none none-out nonTYR APEdihe_aannn APEdist_ooon ZVG Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCWA 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCWB 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCWC 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8SCWD 2.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZVA Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRUA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRUB 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRUC 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRUD 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T12 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYC 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYD 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 460 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4RMZA 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T20 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4RMZB 2.2 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T20 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVMA 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVMB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVMC 2.1 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii VDC Type1 160 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVNA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 167 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVNB 1.95 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVNC 1.95 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TX0A 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VEU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TX0B 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VEU Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCBA 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCBB 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCBC 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCBD 1.85 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii X1T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCCA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii WFQ Type1 160 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8UCCB 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii WFQ Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THWA 2.44 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii NBK Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THWB 2.44 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii NBK Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THXA 1.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii N9Z Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THXB 1.99 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N9Z Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THZA 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NB5 Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6THZB 2.38 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NB5 Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TI8A 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TI8B 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 165 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TI8C 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TI8D 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NBW Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG2A 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG2B 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG2C 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG2D 3.031 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B6I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG3A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4U Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG3B 2.11 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B4U Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG5A 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7R Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG5B 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7R Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9GA 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9GB 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9GC 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9GD 1.88 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9JA 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 161 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9JB 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 161 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9JC 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9JD 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDR Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9KA 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 162 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9KB 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 158 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9KD 1.87 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1JDQ Type1 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O94A 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O94B 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O94C 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O94D 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LRS Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O95A 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O95B 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O95C 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O95D 1.77 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LSV Type1 161 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O9DA 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O9DB 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O9DC 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6O9DD 2.51 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii LTY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6UYAA 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 163 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6UYAB 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6UYAC 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6UYAD 1.74 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii QL7 Type1 162 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3IA 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CKN Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6F3IB 2.14 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii CKN Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6RFIA 2.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1H Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6RFIB 2.31 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1H Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6RFJA 2.61 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1E Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6RFJB 2.61 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K1E Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG1A 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B8I Type1 165 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 7QG1B 2.07 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B8I Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIQA 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIQB 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIQC 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIQD 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BV Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIRA 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BY Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIRB 2.64 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8BY Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UISA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UISB 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UISC 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 162 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UISD 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8C1 Type1 165 - 458 0 TPO342,TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UITA 1.84 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CD Type1 162 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UITB 1.84 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CD Type1 164 - 458 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIUA 2.02 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 165 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5UIUB 2.02 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 164 - 458 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3WA 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 162 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3WB 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3WC 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3WD 1.976 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFO Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3XA 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 162 - 460 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3XB 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3XC 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8W3XD 1.765 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1AFH Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V1OA 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V1OB 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V1OC 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V1OD 2.92 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii Y9T Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2FA 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2FB 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 162 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2FC 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 160 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2FD 2.09 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJU Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2LA 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2LB 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 163 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2LC 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8V2LD 2.43 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YK0 Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATBAAA 2.35 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O0H Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATBBBB 2.35 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O0H Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATLAAA 2.464 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O6X Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATLBBB 2.464 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O6X Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATNAAA 2.171 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O06 Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8ATNBBB 2.171 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii O06 Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR6AAA 2.167 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6I Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR6BBB 2.167 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6I Type1 165 - 459 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR7AAA 2.119 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6R Type1 165 - 458 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8BR7BBB 2.119 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii R6R Type1 165 - 458 0 TPO345,SEP346 K400A,E401A,E402A Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8DKSA 2.45 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii SO9 Type1 165 - 459 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8DKSB 2.45 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii SO9 Type1 164 - 459 0 SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8WTFA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 8CG Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGDA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 165 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGDD 2.1 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn J87 Type1 164 - 458 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGEA 1.401 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DL1 Type1 165 - 459 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGED 1.401 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn DL1 Type1 164 - 457 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U9AA 2.8 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4YO6D 2.32 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4GD, 4GD Type1, Allosteric 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TIAA 2.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ND2, ND2, ND2, ND2 Type1, Allosteric, Allosteric, Allosteric 163 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6TIAB 2.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ND2, ND2, ND2, ND2 Type1, Allosteric, Allosteric, Allosteric 164 - 459 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1SB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1.5_Back 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 9R9KC 1.87 Inactive DFGin‑BLAplus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A1JDQ Type1 164 - 460 0 TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYA 2.15 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYB 2.15 Inactive DFGin‑BLBminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGFB 2.61 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 164 - 460 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVMD 2.1 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnni VDC Type1 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U97B 2.65 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U9AB 2.8 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EG9A 2.414 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni 0LI Type2 164 - 459 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EG9B 2.414 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 0LI Type2 165 - 459 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGAA 2.512 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoio APEdist_nnni J8A Type2 166 - 459 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 6EGAB 2.512 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aaiii APEdist_nnni J8A Type2 164 - 459 0 None None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5KX7A 2.8 Inactive None‑None none-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 192 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 8TVND 1.95 Inactive None‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VE9 Type1 165 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN AF-P53667-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN AF-P53667-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVJB 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiai APEdist_niii No_ligand No_ligand 330 - 637 0 None D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 3S95A 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 3S95B 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5NXCL 2.25 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiai APEdist_nnno 9DB Type1 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK2 LIMK2_HUMAN AF-P53671-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN AF-P53671-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo LH0 Type1 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 334 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaiai APEdist_oioo A1H41 Type1 331 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_oooo T3B Type2 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoao APEdist_iooo T3B Type2 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 5NXDA 1.9 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LRRK1 LRRK1_HUMAN AF-Q38SD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1230 - 1530 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN AF-Q38SD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1230 - 1530 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN 8E04A 3.8 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 381 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN 8E05A 4.6 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN 8E05B 4.6 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN 8E06A 4.3 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 51 - 2007 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK1 LRRK1_HUMAN 8FACA 3.92 Inactive DFGout‑None in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 341 - 2013 0 None None Leucine-rich repeat serine/threonine-protein kinase 1 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1867 - 2142 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN AF-Q5S007-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1867 - 2142 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TXZA 3.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8SMCC 4.02 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii TVT Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U7HC 3.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0T Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO7C 3.52 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZGA 2.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 1333 - 2522 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP8A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VNOA 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP6A 3.47 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 6VP7A 3.5 Inactive DFGin‑BLBplus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1330 - 2525 0 TPO1343 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZHA 3.9 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 627 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 9CHOA 7.8 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aaiii APEdist_nnni A1N Type1 543 - 2527 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHTA 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHTB 3.5 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LHWA 3.7 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 540 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LI4A 3.1 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO2E 4.13 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO8C 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO8E 3.88 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9F 3.48 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH5A 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH5C 4.0 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 7LI3A 3.8 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 9CI3A 3.96 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 907 - 2527 0 SEP910,SEP935 None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZBA 3.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U7LA 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U7LB 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8AB 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8AC 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8BA 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8BB 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TYQA 2.99 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1335 - 2525 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9E 3.48 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaiii APEdist_iioi ATP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 9DMIA 3.35 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnoi A1A7Q Type2 1334 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZEA 2.9 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1624 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZFA 3.4 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 587 - 2522 0 None I2020T Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8VH4A 4.1 Inactive None‑None out-none out-out nonTYR APEdihe_aaioi APEdist_iioi ANP ATPlike 12 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U1BA 3.7 Inactive None‑None none-none none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1952 - 2521 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL MAP3K10 M3K10_HUMAN AF-Q02779-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 90 - 367 0 None None Mitogen-activated protein kinase kinase kinase 10 Homo sapiens
TKL MAP3K10 M3K10_HUMAN AF-Q02779-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 90 - 367 0 None None Mitogen-activated protein kinase kinase kinase 10 Homo sapiens
TKL MAP3K11 M3K11_HUMAN AF-Q16584-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11 Homo sapiens
TKL MAP3K11 M3K11_HUMAN AF-Q16584-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11 Homo sapiens
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CENA 1.7 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaooi APEdist_iioo No_ligand No_ligand 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEOA 2.28 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50D Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEPA 1.99 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50E Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CEQA 1.911 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 50F Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5VO1A 2.45 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FS Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5VO2A 2.96 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno 9FV Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OURA 1.95 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W38 Type1 118 - 396 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OUSA 2.2 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3I Type1 118 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8OUTA 1.935 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno W3C Type1 118 - 399 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 9CDYA 1.5 Inactive DFGin‑BLBplus out-na out-out nonTYR APEdihe_aaooi APEdist_nnoo A1AZ8 Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 8DEGA 2.79 Inactive DFGin‑BLBplus out-na none-out nonTYR APEdihe_aaooi APEdist_nnno SIQ Type1 117 - 398 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 9CDXA 2.38 Inactive DFGin‑None out-na none-out nonTYR APEdihe_aaooi APEdist_nnno A1AZP Type1 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K13 M3K13_HUMAN AF-O43283-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 160 - 417 0 None None Mitogen-activated protein kinase kinase kinase 13 Homo sapiens
TKL MAP3K13 M3K13_HUMAN AF-O43283-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 160 - 417 0 None None Mitogen-activated protein kinase kinase kinase 13 Homo sapiens
TKL MAP3K20 M3K20_HUMAN AF-Q9NYL2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 270 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN AF-Q9NYL2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 270 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5HESB 2.14 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 032 Type1 7 - 298 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWB 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWC 2.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGS Type1.5_Front 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K21 M3K21_HUMAN AF-Q5TCX8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 116 - 408 0 None None Mitogen-activated protein kinase kinase kinase 21 Homo sapiens
TKL MAP3K21 M3K21_HUMAN AF-Q5TCX8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 116 - 408 0 None None Mitogen-activated protein kinase kinase kinase 21 Homo sapiens
TKL MAP3K21 M3K21_HUMAN 4UYAA 2.8 Inactive DFGin‑BLBplus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn AGS ATPlike 115 - 437 0 None A214G,S303A,T307A Mitogen-activated protein kinase kinase kinase 21 Homo sapiens
TKL MAP3K7 M3K7_HUMAN AF-O43318-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 294 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN AF-O43318-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 294 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5V5NA 2.006 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno EDH Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 7NTHA 1.97 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno URW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 7NTIA 1.98 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno UWZ Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JGAA 2.0 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6KC Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JGDA 3.101 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6KD Type1 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 9FPDA 2.402 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_iiii A1IED Type1 31 - 496 0 TPO187,SEP192 None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 2EVAA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ADN Type1 31 - 305 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L3PA 2.68 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 1UH Type1 31 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JGBA 2.8 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno 6JV Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L52A 2.54 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1UL Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L53A 2.55 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1UO Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 8GW3A 2.05 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 27 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JH6A 2.365 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno T92 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5GJGA 2.61 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6V5 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 8GW3B 2.05 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 27 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 8GW3C 2.05 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 25 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 8GW3D 2.05 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 27 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5E7RA 2.11 Inactive DFGout‑BBAminus none-none none-out nonTYR APEdihe_aaooi APEdist_nnno 5KW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 2YIYA 2.49 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno YIY Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4O91A 2.393 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno NG2 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5GJDA 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno 6V3 Type2 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5J9LA 2.752 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6HF Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5J7SA 2.368 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6H3 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5GJFA 2.89 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaooi APEdist_iiio 6V4 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5J8IA 2.404 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6H4 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JK3A 2.371 Inactive None‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6L4 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K9 M3K9_HUMAN AF-P80192-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 136 - 413 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN AF-P80192-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 136 - 413 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 4UY9A 2.81 Inactive DFGin‑BLBplus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 135 - 447 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 4UY9B 2.81 Inactive DFGin‑BLBplus in-none out-out nonTYR APEdihe_aaoni APEdist_oooo No_ligand No_ligand 135 - 449 0 None None Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL MAP3K9 M3K9_HUMAN 3DTCA 2.6 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaini APEdist_nnno VIN Type1 136 - 405 0 None T312A Mitogen-activated protein kinase kinase kinase 9 Homo sapiens
TKL RAF1 RAF1_HUMAN AF-P04049-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 341 - 616 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN AF-P04049-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 341 - 616 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AYAA 2.59 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 342 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AYAC 2.59 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXAA 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXAC 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXCA 4.16 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXCC 4.16 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UG 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VG 3.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1 341 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 3OMVB 4.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_nooo SM5 Type1 340 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UC 2.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VC 3.5 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AY7A 2.41 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 343 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMRA 3.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 625 0 SEP621 Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMSA 3.3 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 343 - 610 0 None Q156R,Y340D,Y341D,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMQA 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 341 - 612 0 None Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9MMPA 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo AGS ATPlike 138 - 630 0 SEP259,SEP621 Q156R,D587E RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8CPDA 3.46 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8CPDB 3.46 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 3OMVA 4.0 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nioo SM5 Type1 340 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8CHFA 4.25 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio 29L Type1 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8CHFB 4.25 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaioi APEdist_iiio 29L Type1 341 - 626 0 SEP621 Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8GFTD 3.8 Inactive None‑None none-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 404 - 611 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8U1LC 3.7 Inactive None‑None none-none none-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 418 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 7Z37CP1 3.67 Inactive None‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 406 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 7Z38C 3.16 Inactive None‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 406 - 615 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 8GAED 3.3 Inactive None‑None none-na none-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 404 - 610 0 None None RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RIPK1 RIPK1_HUMAN AF-Q13546-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 295 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN AF-Q13546-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 295 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q31B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno TME, A1CNU Allosteric, Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZZA 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU5 Type1 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C3EB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type1 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7XMKA 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno GO4 Type1 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7XMKB 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn GO4 Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7YDXB 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 8I2NA 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5HX6B 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 65U Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5TX5B 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 7MJ Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6OCQA 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6RLNB 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn K8K Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTGB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IPG, RCM Type1, Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7YDXA 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 8I2NB 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FD0A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 3IU Type2 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FD0B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 3IU Type2 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4NEUA 2.57 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aaiii APEdist_nnni Q1A Type2 6 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4NEUB 2.57 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn Q1A Type2 7 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTGA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IPG Type3, Type1 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTYB 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IKX Type3, Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN AF-O43353-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN AF-O43353-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8AZAA 3.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8AZAB 3.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR2A 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR2B 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OA 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OB 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OC 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OD 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OE 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OF 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OG 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OH 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OI 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OJ 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OK 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OL 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OM 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5ON 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OO 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5OP 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6HMXA 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6HMXB 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZEB 2.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZJB 2.53 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nioo M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6FU5A 3.26 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FD 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR5A 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR5B 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J79A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GE Type1 2 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J79B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 6GE Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG2A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG2B 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6UL8A 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6UL8B 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RN8A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RN8B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RNAA 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RNAB 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8X2OA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8X2OB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5JA 2.85 Inactive DFGin‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5W5JB 2.85 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 10 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6FU5B 3.26 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 9F3VA 1.943 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 9F3VB 1.943 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR8A 2.79 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 4C8BA 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoni APEdist_nnno 0LI Type2 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 4C8BB 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 0LI Type2 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR7A 2.71 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK3 RIPK3_HUMAN AF-Q9Y572-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN AF-Q9Y572-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3B 3.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1 12 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK4 RIPK4_HUMAN AF-P57078-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 4 Homo sapiens
TKL RIPK4 RIPK4_HUMAN AF-P57078-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 4 Homo sapiens
TKL TESK1 TESK1_HUMAN AF-Q15569-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 46 - 321 0 None None Dual specificity testis-specific protein kinase 1 Homo sapiens
TKL TESK1 TESK1_HUMAN AF-Q15569-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 46 - 321 0 None None Dual specificity testis-specific protein kinase 1 Homo sapiens
TKL TESK2 TESK2_HUMAN AF-Q96S53-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 319 0 None None Dual specificity testis-specific protein kinase 2 Homo sapiens
TKL TESK2 TESK2_HUMAN AF-Q96S53-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 319 0 None None Dual specificity testis-specific protein kinase 2 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8UA 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 502 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2NA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8SA 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN AF-P36897-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 197 - 502 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN AF-P36897-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 197 - 502 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8TA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1B6CB 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1B6CD 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1B6CF 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1B6CH 2.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 175 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1IASA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1IASB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1IASC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1IASD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1IASE 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8XA 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 200 - 503 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E90A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 200 - 499 0 None T204D,I211V,Y249F,S280T,Y282F,S287N,A350C,L352F TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5USQA 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8LY Type1 200 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1RW8A 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 580 Type1 200 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5FRIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZUQ Type1 200 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1VJYA 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii 460 Type1 201 - 503 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3GXLA 1.8 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii QIG Type1 201 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3HMMA 1.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 855 Type1 201 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 9F6XA 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IAZ Type1 200 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X0MA 1.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WA Type1 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2FA 1.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WJ Type1 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2GA 1.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WK Type1 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 9J9DA 1.337 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii A1L30 Type1 202 - 502 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2WOTA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZZG Type1 200 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2WOUA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZZF Type1 200 - 496 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 8YHLA 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D6I Type1 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8WA 1.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 200 - 501 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5E8ZA 1.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QIKA 1.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2M Type1 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QILA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2V Type1 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QTZA 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QMY Type1 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QU0A 1.67 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QMV Type1 200 - 502 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3TZMA 1.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii 085 Type1 200 - 496 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 1PY5A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi PY1 Type1 200 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OA 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OB 3.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAA 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAB 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAC 3.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAD 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAE 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 8YHFA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D6I Type1 201 - 498 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2JA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WN Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2KA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WO Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QIMA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2Y Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 6B8YA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D0A Type1.5_Back 200 - 502 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OC 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OD 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OE 3.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFE 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E8YA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN AF-P37173-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 236 - 548 0 None None TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN AF-P37173-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 236 - 548 0 None None TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 8YGZA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 240 - 541 0 None None TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E8VA 1.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E91A 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5L4 Type1 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5QINA 1.57 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii J2V Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 7DV6A 2.39 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HJF Type1 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TKL TNNI3K TNI3K_HUMAN AF-Q59H18-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN AF-Q59H18-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 455 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFA 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFB 3.07 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn 4CV Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFC 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo 4CV Type1 452 - 725 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFFD 3.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CV Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 6B5JA 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 6B5JB 2.97 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanai APEdist_nnnn CV4 Type1 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 6B5JC 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nooo CV4 Type1 451 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 6B5JD 2.97 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno CV4 Type1 452 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFIA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFIB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFIC 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnno 4CW Type1 441 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 4YFID 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_nnno 4CW Type1 451 - 729 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL LYS6 D3KTZ6_LOTJA 9GB9A 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9B 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9C 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9D 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHB 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 580 - 877 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHC 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 580 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 578 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL LYK3 LYK3_MEDTR 9GFZA 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 302 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYK3 LYK3_MEDTR 9GFZB 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 307 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK A0A811MC32_9POAL 8HOAA 1.676 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaooo APEdist_nnno ATP, HX2 ATPlike, Allosteric 90 - 387 0 None None non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK3 RIPK3_MOUSE 4M66A 2.401 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 15 - 312 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M66B 2.401 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 313 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2B 2.39 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWYA 2.52 None DFGin‑BLAminus none-none none-none nonTYR APEdihe_aannn APEdist_nnnn A1D97 Type1 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0A 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1D99 Type1 15 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0B 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn A1D99 Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGA 2.03 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn LKR Type1 14 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGB 2.03 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LKR Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHA 2.38 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHB 2.38 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWB 1.93 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo A1D96 Type1.5_Back 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZB 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ZOV Type1.5_Back 14 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXB 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo A1D96 Type1.5_Back 14 - 313 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWYB 2.52 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aannn APEdist_nnnn A1D97 Type1 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVB 2.78 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1EJP Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVC 2.78 Inactive DFGin‑None out-none out-none nonTYR APEdihe_aannn APEdist_nnnn A1EJP Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVD 2.78 Inactive DFGin‑None out-none out-none nonTYR APEdihe_aanni APEdist_nnnn A1EJP Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVA 2.78 Inactive DFGin‑None out-none out-out nonTYR APEdihe_aaini APEdist_nnno A1EJO, A1EJP Type1, Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOA 2.1 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1FN Type2 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOB 2.1 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 1FN Type2 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2A 2.39 Inactive DFGout‑None in-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 1SU Type2 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX3A 2.07 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn A1EAA Type2 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX3B 2.07 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn A1EAA Type2 15 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNIA 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 9 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNJA 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo 2V9 Type1 10 - 289 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNLA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo STU Type1 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNMA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo VX6 Type1 10 - 289 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNKA 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo B6J Type1.5_Back 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL PTO Q40234_SOLPI 2QKWB 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 321 0 SEP198,TPO199 None Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 31 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKB 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 319 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKC 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 33 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKD 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 31 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PR1RK2 A0A061FLD4_THECC 6CTHA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE7 Type1 255 - 554 0 None None Concanavalin A-like lectin protein kinase family protein Theobroma cacao

TKL / All / All

Total number of chains: 109
Active chains: 13
Total number of genes: 20
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 60 55.0% 4F0FA
DFGin None 12 11.0% 3TL8G
DFGin BLBplus 11 10.1% 7CTXB
None None 9 8.3% 8BW9D
DFGout None 6 5.5% 3P86A
DFGin ABAminus 4 3.7% 3TL8A
DFGin BLBminus 4 3.7% 4F0GA
DFGin BLBtrans 2 1.8% 9GFZA
DFGin BLAplus 1 0.9% 6M0UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL BAK1 BAK1_ARATH 3TL8A 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 273 - 576 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8D 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 583 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8H 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 580 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3UIMA 2.2 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii ANP ATPlike 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3ULZA 2.6 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 272 - 573 0 SEP290,TPO312,TPO446,TPO449,TPO450,TPO455 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8G 2.5 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 578 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BIK1 BIK1_ARATH 5TOSA 2.35 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 52 - 360 0 SEP253 None Serine/threonine-protein kinase BIK1 Arabidopsis thaliana
TKL BIK1 BIK1_ARATH 5TOSB 2.35 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 52 - 360 0 SEP253 None Serine/threonine-protein kinase BIK1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPWA 2.431 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 866 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6A 1.898 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CARK1 CARK1_ARATH 5XD6B 1.898 Inactive DFGin‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 50 - 350 0 None None Protein CYTOSOLIC ABA RECEPTOR KINASE 1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3PPZB 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 540 - 810 0 TPO704,SEP707,SEP710 None Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3PPZA 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 540 - 810 0 TPO704,SEP707,SEP710 None Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3P86B 2.496 Inactive DFGin‑None in-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 543 - 810 0 None D676N Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL CTR1 CTR1_ARATH 3P86A 2.496 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 544 - 810 0 None D676N Serine/threonine-protein kinase CTR1 Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXA 2.23 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDXB 2.23 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYA 2.28 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDYB 2.28 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVA 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDVB 1.97 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ATP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWA 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 521 - 815 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 7XDWB 1.926 None DFGin‑BLAminus in-none in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 522 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 9UBIA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo OT5 Type1 521 - 818 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL FERONIA FERON_ARATH 9UBIB 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni OT5 Type1 521 - 816 0 None None Receptor-like protein kinase FERONIA Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TA 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TD 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TI 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TJ 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5TM 3.4 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5UC 3.9 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 172 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J5VC 4.25 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 172 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL PBL2 PBL2_ARATH 6J6IA 3.7 Inactive None‑None none-none none-out nonTYR APEdihe_aaooo APEdist_nnno U5P, U5P Allosteric, Allosteric 135 - 367 0 None None Probable serine/threonine-protein kinase PBL2 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXA 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTXB 2.907 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None None Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SYMRK E6YC17_ARAHY 6M0UA 2.29 Inactive DFGin‑BLAplus out-na none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 582 - 881 0 None K625E Nodulation receptor kinase Arachis hypogaea
TKL ROCO4 ROCO4_DICDI 4YZMB 3.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiai APEdist_nioo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F0FA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1OA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP ATPlike 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1MA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP, BTB ATPlike, Allosteric 1019 - 1292 0 None G1179S Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4YZMA 3.0 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoai APEdist_nnoo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4YZNA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoai APEdist_iioo 4K5 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F1TA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo H52, H52 Type1, Allosteric 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL ROCO4 ROCO4_DICDI 4F0GA 2.0 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
TKL KSR Q24171_DROME 8BW9D 3.32 Inactive None‑None none-none out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 731 - 947 0 None None AT08303p Drosophila melanogaster
TKL LYS6 D3KTZ6_LOTJA 9GB9A 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9B 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9C 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL LYS6 D3KTZ6_LOTJA 9GB9D 1.85 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi No_ligand No_ligand 306 - 599 0 None D460N non-specific serine/threonine protein kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHB 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 580 - 877 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHC 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 580 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL None Q8LKX1_LOTJA 8PEHA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 578 - 875 0 None D738N Nodulation receptor kinase Lotus japonicus
TKL LYK3 LYK3_MEDTR 9GFZA 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 302 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYK3 LYK3_MEDTR 9GFZB 2.5 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi No_ligand No_ligand 307 - 596 0 None D459N LysM domain receptor-like kinase 3 Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL RIPK A0A811MS43_9POAL 8HODA 1.95 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 82 - 379 0 None S262A,T263A non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK A0A811MC32_9POAL 8HOAA 1.676 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaooo APEdist_nnno ATP, HX2 ATPlike, Allosteric 90 - 387 0 None None non-specific serine/threonine protein kinase Miscanthus lutarioriparius
TKL RIPK3 RIPK3_MOUSE 4M66A 2.401 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 15 - 312 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M66B 2.401 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 313 0 None C111A Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2B 2.39 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWYA 2.52 None DFGin‑BLAminus none-none none-none nonTYR APEdihe_aannn APEdist_nnnn A1D97 Type1 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0A 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni A1D99 Type1 15 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX0B 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn A1D99 Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGA 2.03 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn LKR Type1 14 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVGB 2.03 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn LKR Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHA 2.38 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LVHB 2.38 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn MYF Type1 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWB 1.93 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo A1D96 Type1.5_Back 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZB 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ZOV Type1.5_Back 14 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXB 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo A1D96 Type1.5_Back 14 - 313 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 4M69A 2.497 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 12 - 312 0 SEP184,TPO231,SEP232 None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWYB 2.52 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aannn APEdist_nnnn A1D97 Type1 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVB 2.78 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn A1EJP Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVC 2.78 Inactive DFGin‑None out-none out-none nonTYR APEdihe_aannn APEdist_nnnn A1EJP Type1 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVD 2.78 Inactive DFGin‑None out-none out-none nonTYR APEdihe_aanni APEdist_nnnn A1EJP Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFVA 2.78 Inactive DFGin‑None out-none out-out nonTYR APEdihe_aaini APEdist_nnno A1EJO, A1EJP Type1, Type1 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOA 2.1 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1FN Type2 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOB 2.1 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 1FN Type2 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX2A 2.39 Inactive DFGout‑None in-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 1SU Type2 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX3A 2.07 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn A1EAA Type2 15 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX3B 2.07 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn A1EAA Type2 15 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNIA 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 9 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNJA 2.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo 2V9 Type1 10 - 289 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNLA 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo STU Type1 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNMA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo VX6 Type1 10 - 289 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNKA 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo B6J Type1.5_Back 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TKL PTO Q40234_SOLPI 2QKWB 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 321 0 SEP198,TPO199 None Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 31 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKB 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 319 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKC 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 33 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PTO Q40234_SOLPI 3HGKD 3.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 31 - 318 0 SEP198,TPO199 D193G Protein kinase Solanum pimpinellifolium
TKL PR1RK2 A0A061FLD4_THECC 6CTHA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE7 Type1 255 - 554 0 None None Concanavalin A-like lectin protein kinase family protein Theobroma cacao