All / ABAminus / All

Total number of chains: 823
Active chains: 1
Total number of genes: 80
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 823 100.0% AF-Q504Y2-K3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC GRK5 GRK5_HUMAN 9CKOA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 1 - 542 0 None None G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9BRKA 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARA Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9BRLA 2.73 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARB Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9BRPA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARF Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC PKN1 PKN1_HUMAN 4OTDA 2.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 605 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1
AGC PKN1 PKN1_HUMAN 4OTGA 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2V9 Type1 605 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1
AGC PRKACA KAPCA_HUMAN 4AE6A 2.1 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE6B 2.1 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE9A 2.3 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE9B 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 7Y1GB 2.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii I5G Type1 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9DC6A 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3I Type1 16 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9DC6B 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3I Type1 16 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 3AMBA 2.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 4 - 351 0 SEP11,TPO198,SEP339 K48R,L96Q,M121L,V124A,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 8X5LA 2.75 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo RKD Type1 17 - 351 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 8X5LB 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iioo RKD Type1 17 - 334 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKCB KPCB_HUMAN 8SE2A 2.95 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 19 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE3A 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE4A 2.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE4B 2.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCI KPCI_HUMAN 8R3YI 3.68 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 585 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 8R3XA 2.591 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 8R3XB 2.591 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 587 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 6ILZA 3.261 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKG1 KGP1_HUMAN 7T4UA 1.99 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EX6 Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4UB 1.99 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EX6 Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4WA 2.23 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EZJ Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4WB 2.23 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EZJ Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4TA 2.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PCG, ATP Allosteric, ATPlike 204 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7T4TB 2.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PCG, ATP Allosteric, ATPlike 204 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NDMA 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NCZA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NCZB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NCZC 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 404 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NCZD 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NDMB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NDMC 3.3 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 3ND Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3NDMD 3.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNFA 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 7 - 401 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNFB 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNFC 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNFD 2.45 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4V Type1 7 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNGA 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 7 - 401 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNGB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNGC 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNGD 2.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4Y Type1 7 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNHA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 401 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNHB 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNHC 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 5WNHD 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1
AGC ROCK2 ROCK2_HUMAN 6P5MC 2.65 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 18 - 417 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6P5MD 2.65 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 18 - 417 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7QA 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7QB 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oioo No_ligand No_ligand 28 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7QC 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7QD 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7RA 3.33 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 81G Type1 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 5U7RC 3.33 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiio 81G Type1 25 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6P5PA 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O1V Type1 27 - 417 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6P5PB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnio O1V Type1 27 - 417 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6P5PC 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O1V Type1 28 - 416 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6P5PD 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio O1V Type1 26 - 416 0 None F270Y Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8X8YB 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio YEA Type1 29 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8X8ZA 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEI Type1 31 - 416 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8X8ZB 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio YEI Type1 29 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8X92A 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEW Type1 29 - 416 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8X92B 2.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_noio YEW Type1 29 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4WOTA 2.93 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4WOTB 2.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4WOTC 2.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4WOTD 2.93 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nooo 3SG Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 9HFPA 2.92 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IUI Type1 23 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4L6QA 2.79 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1WU Type1 27 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 4L6QB 2.79 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1WU Type1 27 - 417 0 None None Rho-associated protein kinase 2
AGC RPS6KA3-1 KS6A3_HUMAN 4NW5A 1.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2NR Type1 51 - 359 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KA3-1 KS6A3_HUMAN 4NW6A 1.74 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2NS Type1 51 - 359 0 None None Ribosomal protein S6 kinase alpha-3
AGC RPS6KB1 KS6B1_HUMAN 4RLPA 2.79 Inactive DFGin‑ABAminus none-none in-out nonTYR APEdihe_aaiii APEdist_nnno 72B Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 4L3JA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 4L3LA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 7N91A 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 7N91B 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 7N93A 2.74 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 1SK Type1 87 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 7N93B 2.74 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SK Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 3A62A 2.35 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo STU Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 3WE4A 1.995 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 3WF5A 2.099 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ8 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 3WF6A 2.031 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ9 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 4L45A 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412E Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 4L42A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 5FI Type1 84 - 417 0 None S403E,A404E,N405Q,Q406E,V407M,L409R,G410D,T412E,V414I,P416D,S417W Ribosomal protein S6 kinase beta-1
AGC RPS6KB1 KS6B1_HUMAN 4L46A 3.01 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 80 - 417 0 TPO412 None Ribosomal protein S6 kinase beta-1
CAMK AURKA AURKA_HUMAN 4C3PD 2.69 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nooo ACP ATPlike 125 - 390 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWA 2.7 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWB 2.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 507 - 390 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 8GUWC 2.7 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DPVA 2.285 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5DN, SKE Allosteric, Type1 127 - 389 0 None T287A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DR6A 2.534 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5E1, SKE Allosteric, Type1 127 - 390 0 None T287A Aurora kinase A
CAMK AURKA AURKA_HUMAN 2WTWA 3.302 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoo ZZL Type1 128 - 389 0 None L215R,T217E,R220K Aurora kinase A
CAMK AURKA AURKA_HUMAN 3E5AA 2.3 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 125 - 389 0 TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 2NP8A 2.25 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn CC3 Type1 127 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 4BYIA 2.6 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno FH3 Type1 126 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5ONEA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo 9YQ Type1 127 - 391 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DT0A 2.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo SKE Type1 127 - 390 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 3UODA 2.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiio 0C3 Type1 124 - 389 0 None T287D Aurora kinase A
CAMK AURKA AURKA_HUMAN 3UP2A 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 0C8 Type1 124 - 389 0 None T287D Aurora kinase A
CAMK AURKA AURKA_HUMAN 4DEAA 2.45 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo NHI Type1 124 - 389 0 None T287D Aurora kinase A
CAMK AURKA AURKA_HUMAN 5AAFA 2.78 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnno NL4 Type1 126 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5AAGA 2.85 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno 6F2 Type1 127 - 388 0 None C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 6GRAA 2.6 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn F8Z Type1.5_Front 126 - 389 0 None None Aurora kinase A
CAMK AURKC AURKC_HUMAN 9ESAAAA 2.8 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 32 - 306 0 None R195A,R196A,K197A Aurora kinase C
CAMK AURKC AURKC_HUMAN 9ESABBB 2.8 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 32 - 306 0 None R195A,R196A,K197A Aurora kinase C
CAMK AURKC AURKC_HUMAN 6GR9A 2.25 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 37 - 305 0 TPO39,TPO198 None Aurora kinase C
CAMK AURKC AURKC_HUMAN 6GR8A 1.75 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii F8Z Type1.5_Front 36 - 303 0 TPO39,TPO198 None Aurora kinase C
CAMK DAPK1 DAPK1_HUMAN 1WVYA 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi STU Type1 4 - 276 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 9INVA 1.61 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi HCC Type1 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 9INWA 1.52 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi A1L2V Type1 2 - 277 0 None None Death-associated protein kinase 1
CAMK DCLK1 DCLK1_HUMAN 7F3GB 2.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXT Type1 383 - 648 0 None None Serine/threonine-protein kinase DCLK1
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4A 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4B 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4C 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 351 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4D 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 349 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4E 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4F 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4G 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4H 3.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 47 - 358 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4I 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 347 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4J 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 350 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4K 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4L 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 354 0 None S216G MAP kinase-activated protein kinase 2
CAMK MARK2 MARK2_HUMAN 3IECB 2.2 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 49 - 363 0 None R146W Serine/threonine-protein kinase MARK2
CAMK MARK2 MARK2_HUMAN 3IECD 2.2 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 49 - 363 0 None R146W Serine/threonine-protein kinase MARK2
CAMK MARK2 MARK2_HUMAN 5EAKB 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 24R Type1 51 - 363 0 None None Serine/threonine-protein kinase MARK2
CAMK MELK MELK_HUMAN 4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 5TX3A 2.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7MY Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MYLK4 MYLK4_HUMAN 2X4FA 2.67 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo 16X Type1 80 - 373 0 None None Myosin light chain kinase family member 4
CAMK MYLK4 MYLK4_HUMAN 2X4FB 2.67 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo 16X Type1 81 - 370 0 None None Myosin light chain kinase family member 4
CAMK PIM1 PIM1_HUMAN 4RBLA 2.55 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O7 Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4RC2A 2.096 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O8 Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4RC3A 2.338 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3OA Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4RC4A 2.651 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3OK Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4I41A 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MIX, MIX Type1, Allosteric 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PLK4 PLK4_HUMAN 9O63A 2.26 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn A1CAD Type1 2 - 266 0 None None Serine/threonine-protein kinase PLK4
CAMK PRKAA1 AAPK1_HUMAN 6C9FA 2.924 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii R34, STU Allosteric, Type1 22 - 558 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1
CAMK PRKAA1 AAPK1_HUMAN 7JIJA 5.5 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1
CAMK PRKAA2 AAPK2_HUMAN 5ISOA 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
CAMK PRKAA2 AAPK2_HUMAN 5ISOC 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 550 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
CAMK PRKAA2 AAPK2_HUMAN 6B1UC 2.77 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 9 - 552 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
CAMK RPS6KA1-2 KS6A1_HUMAN 2WNTA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanin APEdist_oooo No_ligand No_ligand 416 - 708 0 None None Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA1-2 KS6A1_HUMAN 2WNTB 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 415 - 709 0 None None Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA1-2 KS6A1_HUMAN 3RNYA 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 418 - 707 0 None None Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA1-2 KS6A1_HUMAN 3RNYB 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 419 - 708 0 None None Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA3-2 KS6A3_HUMAN 4D9TA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_oooo 0JG Type1 415 - 713 0 None None Ribosomal protein S6 kinase alpha-3
CAMK RPS6KA3-2 KS6A3_HUMAN 4D9UA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_oooo 0JH Type1 408 - 714 0 None K591E Ribosomal protein S6 kinase alpha-3
CAMK SIK3 SIK3_HUMAN 8R4VB 1.9 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii XWA Type1 61 - 384 0 TPO221 C121S,C181S,C333S Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4VC 1.9 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii XWA Type1 61 - 385 0 TPO221 C121S,C181S,C333S Serine/threonine-protein kinase SIK3
CAMK STK17A ST17A_HUMAN 7QUEB 2.4 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaini APEdist_oooo F7I Type1 59 - 322 0 None None Serine/threonine-protein kinase 17A
CAMK STK17A ST17A_HUMAN 7QUFA 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooo F8I Type1 50 - 322 0 None None Serine/threonine-protein kinase 17A
CAMK STK17A ST17A_HUMAN 7QUFB 2.6 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_oooo F8I Type1 55 - 322 0 None None Serine/threonine-protein kinase 17A
CAMK TRIB1 TRIB1_HUMAN 6DC0A 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 67 0 None None Tribbles homolog 1
CAMK TRIB1 TRIB1_HUMAN 6DC0B 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 74 0 None None Tribbles homolog 1
CAMK TRIB2 TRIB2_HUMAN 7UPMA 2.7 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 55 - 312 0 None None Tribbles homolog 2
CAMK TTN TITIN_HUMAN 1TKIA 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 1TKIB 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 4JNWA 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32491 0 None None Titin
CAMK TTN TITIN_HUMAN 4JNWB 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iooo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 6YGNA 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin
CAMK TTN TITIN_HUMAN 6YGNB 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin
CK1 TTBK1 TTBK1_HUMAN 8XPZA 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 20 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7QHWAAA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7QHWCCC 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7Q8VA 2.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7Q8WA 2.02 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IO Type1 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 4BTMA 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 4BTMB 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK2 TTBK2_HUMAN 7Q8YA 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 6 - 299 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q8YB 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 7 - 299 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q8ZA 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 6 - 299 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q8ZB 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 7 - 299 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q90A 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 6 - 299 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q90B 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 7 - 299 0 None None Tau-tubulin kinase 2
CK1 VRK2 VRK2_HUMAN 5UU1A 2.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2
CMGC CDK11B CD11B_HUMAN 7UKZA 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZB 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZC 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZD 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 437 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZE 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 435 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZF 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK12 CDK12_HUMAN 8BU2H 3.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVQ Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BU4B 3.09 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQL Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BU4H 3.09 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii RQL Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BU5B 3.134 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii RMF Type1 713 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BU5H 3.134 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMF Type1 713 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BU9H 3.51 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RRC Type1 715 - 1038 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUAB 3.193 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVH Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUAE 3.193 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii RVH Type1 715 - 1033 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUAH 3.193 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RVH Type1 715 - 1034 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUCB 3.85 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKO Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUDB 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RP9 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUDH 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RP9 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUEH 3.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVU Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUIB 3.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RV6 Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUIH 3.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RV6 Type1 715 - 1038 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BULH 3.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RSU Type1 715 - 1034 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUNB 3.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RNF Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUNH 3.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RNF Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUOB 3.58 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RLC Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BURE 3.64 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQU Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUSH 3.26 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMX Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUTB 3.25 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQ5 Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUTH 3.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RQ5 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 7NXKA 3.0 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii UUB Type1 715 - 1040 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 9FMRE 3.9 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii RMF Type1 714 - 1042 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 9FMRH 3.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMF Type1 714 - 1044 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK2 CDK2_HUMAN 8BZOA 3.5 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 14 - 297 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5NEVA 2.97 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 72L Type1 1 - 295 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5NEVC 2.97 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 72L Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK7 CDK7_HUMAN 6XBZJ 2.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 312 0 SEP164 None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 7EGB8 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 7ENC8 4.13 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 311 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 7LBME 4.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 7NVR8 4.5 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7
CMGC CLK1 CLK1_HUMAN 6KHDC 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 3NG Type1 150 - 479 0 None None Dual specificity protein kinase CLK1
CMGC DYRK1A DYR1A_HUMAN 6UIPB 3.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 136 - 478 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6UIPC 3.7 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni Q8J Type1 131 - 477 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC GSK3B GSK3B_HUMAN 6Y9SA 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 6Y9SB 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
CMGC HIPK3 HIPK3_HUMAN 7O7JA 2.81 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6ZV Type1 184 - 551 0 PTR359 None Homeodomain-interacting protein kinase 3
CMGC MAPK1 MK01_HUMAN 8PVUE 3.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 24 - 356 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 1WZYA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoio APEdist_oioo F29 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 1TVOA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FRZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
CMGC MAPK10 MK10_HUMAN 8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4Z9LA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno ANP, 880 Allosteric, Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4KKGA 2.4 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3FI2A 2.28 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JK1 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3FV8A 2.28 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno JK3 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2B1PA 1.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AIZ Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2R9SA 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2R9SB 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2EXCX 2.75 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno JNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3OY1A 1.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 589 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3RTPA 2.4 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 34I Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2O2UA 2.45 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 738 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2WAJA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SNB Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2ZDTA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo 46C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2ZDUA 2.5 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 446 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3FI3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno JK2 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3KVXA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnno FMY Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3V6RA 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3V6RB 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3V6SA 2.97 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3V6SB 2.97 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 1PMNA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 984 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 1PMUA 2.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iooo 9HP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7ORFA 1.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0G3 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2P33A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo J07 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3CGFA 3.0 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo JNF Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3CGOA 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo JNO Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3G90X 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J72 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3G9LX 2.2 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno J67 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3G9NA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J88 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4KKHA 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 1RQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4W4VA 2.01 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3H8 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4W4WA 1.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HJ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4W4XA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HN Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4W4YA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4Y5HA 2.055 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 519 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4X21A 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4X21B 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 47 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EKDA 2.1 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno B9K Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHC 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHD 1.76 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4WHZA 1.79 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 3NL Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3TTIA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo KBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7KSIA 1.726 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3S Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7KSJA 2.06 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3Y Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7KSKA 1.84 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_onoo X3V Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7S1NA 2.11 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 86C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7YL1A 2.48 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo J6F Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8ENJA 2.81 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo WNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8VNXA 2.0 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8VO4A 2.07 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHE Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8VTFA 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 7OREA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0EI, 0EI Type1, Type1 44 - 402 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 2O0UA 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 3DA6A 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo BZ9 Type1.5_Front 46 - 401 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 4U79A 2.23 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3EL Type1.5_Front 44 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK11 MK11_HUMAN 3GC9B 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo B45 Type1 2 - 349 0 None C119S,C162S Mitogen-activated protein kinase 11
CMGC MAPK11 MK11_HUMAN 3GC8A 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo B45 Type1 3 - 349 0 None C162S Mitogen-activated protein kinase 11
CMGC MAPK11 MK11_HUMAN 3GC8B 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo B45 Type1 4 - 349 0 None C162S Mitogen-activated protein kinase 11
CMGC MAPK12 MK12_HUMAN 7CGAB 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAC 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAD 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12
CMGC MAPK8 MK08_HUMAN 6ZR5A 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 3 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 6ZR5B 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 4 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2XRWA 1.33 Inactive DFGin‑ABAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2XS0A 2.6 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ANP ATPlike 6 - 365 0 None T183V,Y185F Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8R5EA 1.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP, Y6K ATPlike, Allosteric 5 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 1UKHA 2.35 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8C 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 10 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8E 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 7 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8F 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 10 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 6F5EB 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 7 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8X5MA 2.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno Y4O Type1 7 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT8A 2.78 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nioo A3O Type1 7 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT8B 2.78 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_iioo A3O Type1 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT8C 2.78 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo A3O Type1 7 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT9A 2.7 Inactive DFGin‑ABAminus out-in out-out nonTYR APEdihe_aaooi APEdist_iooo DVI Type1 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT9B 2.7 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nioo DVI Type1 7 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PT9C 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo DVI Type1 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PTAA 2.41 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo CIF Type1 8 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PTAB 2.41 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo CIF Type1 7 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 8PTAC 2.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo CIF Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 1UKIA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 537 Type1 9 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4E73A 2.27 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 0NR Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4G1WA 2.45 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn G1W Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4HYSA 2.415 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1BJ Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4HYUA 2.152 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1BK Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4IZYA 2.3 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1J2 Type1 8 - 361 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 3PZEA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno CFK Type1 7 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4L7FA 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo 1V5 Type1 7 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 3ELJA 1.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo GS7 Type1 7 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4AWIA 1.91 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo AQ2 Type1 8 - 364 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1B 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1E 3.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1H 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4QTDA 1.5 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo 38Z, ANP Type1, Allosteric 6 - 363 0 None None Mitogen-activated protein kinase 8
CMGC MAPK9 MK09_HUMAN 7N8TA 1.69 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iioo AMP ATPlike 10 - 364 0 None None Mitogen-activated protein kinase 9
CMGC MAPK9 MK09_HUMAN 8ELCA 2.072 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo Y56 Type1 9 - 363 0 None None Mitogen-activated protein kinase 9
CMGC MAPK9 MK09_HUMAN 3E7OA 2.14 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiio APEdist_oooo 35F Type1 9 - 361 0 None C177S,C222S,K250A,K251A,K265A,K270A Mitogen-activated protein kinase 9
CMGC MAPK9 MK09_HUMAN 3E7OB 2.14 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 35F Type1 8 - 362 0 None C177S,C222S,K250A,K251A,K265A,K270A Mitogen-activated protein kinase 9
CMGC SRPK1 SRPK1_HUMAN 5MY8A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXZ Type1 64 - 655 0 None None SRSF protein kinase 1
OTHER BMP2K BMP2K_HUMAN 5I3OA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3OB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3RA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3RB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5IKWA 2.41 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6BU Type1 42 - 338 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A1AB 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo No_ligand No_ligand 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 8QELB 2.451 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo UH3 Type1 258 - 541 0 TPO446 None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER ERN1 ERN1_HUMAN 4Z7HB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioi 4L5 Type1 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER GAK GAK_HUMAN 4O38A 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 25 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4O38B 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 26 - 337 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y7ZA 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y7ZB 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y80A 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo IRE, IRE Type1, Allosteric 25 - 332 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K3A -1.0 Active DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3CEKA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3DBQA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 515 - 796 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2ZMCA 3.14 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6GVJA 2.41 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 515 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5LJJA 3.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AD5 Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5MRBA 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EH0A 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5NW Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6H3KA 2.48 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn FMW Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4JS8A 1.94 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo 1PF Type1 515 - 793 0 TPO675,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4JT3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1PH Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4O6LA 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4O6LB 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4ZEGA 2.33 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 052 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CILA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo FZR Type1 515 - 795 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CHNA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo FZL Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CJAA 2.49 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo G0U Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CLHA 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo G5C Type1 516 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TN9A 2.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo NN5 Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNCA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo O23 Type1 516 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6N6OA 2.6 Inactive DFGin‑ABAminus out-out out-none nonTYR APEdihe_aanni APEdist_nnnn KE7 Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BHZA 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0B Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI0A 2.84 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0W Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI1A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO6 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI2A 3.11 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO8 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4EA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 4T9 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4FA 2.36 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 7CE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4GA 2.65 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaono APEdist_nnoo 7RO Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4HA 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 7RO Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4IA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X20 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4JA 2.5 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo X21 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CV8A 3.0 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno 3D7 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CV9A 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo W2K Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CVAA 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo WBI Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP0A 2.15 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo AU5 Type1 519 - 795 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP1A 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo O38 Type1 519 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP2A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno PWU Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHLA 2.66 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo 0SQ Type1 519 - 796 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHOA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O1 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHYA 2.26 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O4 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI2A 2.67 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5O7 Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI6A 2.01 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5OQ Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI8A 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5OE Type1 519 - 753 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N87A 2.29 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo N66 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP6A 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo PWU Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5O91A 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 796 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6B4WA 2.9 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnoo CQ7 Type1 515 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3VQUA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno O22 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WYXA 2.9 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O38 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WYYA 3.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O17 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N7VA 2.52 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaono APEdist_oooo 8PT Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N84A 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo 8Q5 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N93A 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo 8QE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NA0A 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo 8QZ Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3HMOA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 514 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3HMPA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo CX4 Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP3A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_iooo AU5 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP4A 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo O38 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2ZMDA 2.88 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_oooo 537 Type1 516 - 795 0 None T686A Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7LQDA 1.95 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YB4, TOE Type1, Allosteric 519 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP5A 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7RO, 1KA Type1, Type1 519 - 794 0 None S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNBA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno 8QW Type1.5_Front 517 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N9SA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo 8QW Type1.5_Front 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4
OTHER WEE1 WEE1_HUMAN 9D0SA 1.64 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1R Type1 292 - 574 0 None None Wee1-like protein kinase
STE MAP2K7 MP2K7_HUMAN 6QFLA 2.2 Inactive DFGin‑ABAminus na-na in-out nonTYR APEdihe_aaiai APEdist_nnoi No_ligand No_ligand 102 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6QFTA 2.7 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aanai APEdist_nnnn J0B Type1 102 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6QG4A 2.3 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aannn APEdist_nnnn J0E Type1 111 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6QG7A 2.1 Inactive DFGin‑ABAminus na-na in-out nonTYR APEdihe_aaiai APEdist_nnoi 6HL Type1 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6QHOA 2.7 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aannn APEdist_nnnn J3H Type1 111 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP3K14 M3K14_HUMAN 4IDTA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi T28 Type1 333 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP4K1 M4K1_HUMAN 6NFYA 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi B49 Type1 10 - 292 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 6NFYB 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioi B49 Type1 10 - 292 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE PAK1 PAK1_HUMAN 9N48B 1.85 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BV1 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK4 PAK4_HUMAN 4XBRA 2.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 177 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE STK10 STK10_HUMAN 4USEA 2.65 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aanio APEdist_nnnn R09 Type1 24 - 316 0 None None Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USEB 2.65 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aanio APEdist_nnnn R09 Type1 24 - 316 0 None None Serine/threonine-protein kinase 10
STE STK3 STK3_HUMAN 5DH3B 2.468 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 18 - 302 0 TPO174,TPO180 None Serine/threonine-protein kinase 3
TKL ACVR1 ACVR1_HUMAN 6T6DB 2.56 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MM8 Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T6DC 2.56 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 205 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCA 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 205 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCB 2.67 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii H8H Type1 203 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCC 2.67 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi H8H Type1 201 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ZGCD 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 203 - 498 0 None Q207D Activin receptor type-1
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PRFA 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL TGFBR2 TGFR2_HUMAN 5E8YA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TYR ALK ALK_HUMAN 3LCTA 2.1 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4TT7A 2.1 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao COM, COM Allosteric, Allosteric 1095 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JY4A 2.42 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao W47, W47 Allosteric, Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YHVA 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANLA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1094 - 1402 0 None G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNWA 1.75 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1084 - 1405 0 None C1097S,F1174L ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNXA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1093 - 1404 0 None C1097S,R1275Q ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6CDTA 1.8 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1093 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YJSA 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1094 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3L9PA 1.8 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANSA 1.85 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None L1196M,G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YFXA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CLJA 1.66 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 5P8 Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CD0A 2.23 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANQA 1.76 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AA9A 1.93 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AAAA 1.73 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1401 0 None L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AA8A 1.86 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AABA 2.2 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6MX8A 1.96 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 6GY Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XB7A 2.5 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao GUI Type1 1095 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XBAA 1.95 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 571 Type1 1095 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5FTOA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai YMX Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5FTQA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai U4W Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 8ARJA 1.645 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao NRR Type1 1103 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6E0RA 2.303 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_niiai APEdist_aaai HKJ Type1 1099 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6EBWA 2.455 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai J3Y Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYRA 2.32 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VTA Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYSA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao VTD Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYTA 2.0 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VRM Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XP2A 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_niiai APEdist_aaao VGH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CCBA 2.03 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai OFG Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CCUA 2.0 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWF Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CLIA 2.05 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 5P8 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMOA 2.05 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai YPW Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMTA 1.73 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai GWH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMUA 1.8 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai IV7 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHA 1.9 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_niiai APEdist_aaai 3U9 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CTBA 1.79 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao KVC Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CTCA 2.03 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai J99 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5KZ0A 2.3 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 6YL Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7R7KA 1.831 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 25J Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7R7RA 1.935 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNZA 2.6 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaai NZF Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IUIA 1.88 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 45Q Type1 1089 - 1400 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FODA 2.0 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0UV Type1 1085 - 1405 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3AOXA 1.75 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai EMH Type1 1086 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5A9UA 1.6 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AACA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7BTTA 1.86 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao F8R Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FOBA 1.9 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0US Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FOCA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0UU Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4Z55A 1.55 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 4LO Type1 1093 - 1399 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3LCSA 1.95 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao STU Type1 1096 - 1399 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4MKCA 2.01 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 4MK Type1 1093 - 1401 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 9GBEA 1.58 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao A1IJ8 Type1 1086 - 1401 0 None L1196M,G1202R ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHB 1.9 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 3U9, 3U9 Type1, Allosteric 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4JOAA 2.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 3DK Type1.5_Front 1107 - 1398 0 None S1281G ALK tyrosine kinase receptor
TYR EGFR EGFR_HUMAN 3IKAA 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ER2A 2.662 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAU Type1 697 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9XU9A 2.84 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1E1C Type1 696 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8KFQA 3.22 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai VUZ Type1 697 - 1018 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 697 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 4TRLA 2.452 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 599 - 875 0 PTR772 None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJBA 2.8 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 591 - 965 0 None S897E,S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK0A 1.597 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 91E Type1 602 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK8A 1.761 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 90Z Type1 605 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHA 1.379 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 602 - 889 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHB 1.379 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_niiai APEdist_aaao DXK Type1 602 - 882 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK3A 1.586 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 92Q Type1.5_Back 601 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8QQYA 1.8 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai WT3 Type1.5_Back 605 - 896 0 None None Ephrin type-A receptor 2
TYR IGF1R IGF1R_HUMAN 1K3AA 2.1 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 988 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3A 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3B 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3C 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3D 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPA 3.0 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai PDR Type1 989 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPB 3.0 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPC 3.0 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai PDR Type1 987 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PA 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PB 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PC 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PD 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PE 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PF 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PG 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PH 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PI 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PJ 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PK 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PL 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PM 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PR 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PS 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PT 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR INSR INSR_HUMAN 2AUHA 3.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1011 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 2B4SB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 2B4SD 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 3BU6A 1.95 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR JAK1-2 JAK1_HUMAN 5KHWA 2.47 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LE 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 3EYGA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 3EYHA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5E1EB 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 5JG Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6AAHA 1.83 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6AAHB 1.83 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEA 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NTW Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEB 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NTW Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFA 2.31 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai NTQ Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB 2.31 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai NTQ Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6GGHA 1.7 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai EYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6GGHB 1.7 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai EYQ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6ELRA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai BFK Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6ELRB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai BFK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8B 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKT Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SMBA 2.04 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SMBB 2.04 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LB 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LD 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NL Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NL Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WA 1.86 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WB 1.86 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NT Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZA 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 858 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZB 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZC 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZD 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4A 2.22 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0Q2 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4B 2.22 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0Q2 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6A 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0UJ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6B 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0UJ Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CA 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai C5I Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CB 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai C5I Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J5 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCA 2.35 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J6 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCB 2.35 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDA 1.93 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 15T Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDB 1.93 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 15T Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K6ZA 2.73 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q3 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77B 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8A 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 66P Type1 855 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8B 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 66P Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4A 1.84 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai B7V Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4B 1.84 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai B7V Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUA 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai GYQ Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUB 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai GYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N77A 1.64 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KEJ Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N77B 1.64 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KEJ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N78A 1.83 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEP Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N79A 2.27 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KES Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7BA 1.81 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEY Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7CA 1.69 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7CB 1.69 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7DA 1.78 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KF4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSBA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSBB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCA 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCB 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSDA 1.76 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSDB 1.76 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSEA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSEB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSHA 1.71 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSHB 1.71 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8A 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 8S85A 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 8S85B 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7AA 1.33 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEV Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7AB 1.33 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEV Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHXA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TE Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6BBUA 2.08 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai D7D Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6DBNA 2.48 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai G4J Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6W8LA 2.11 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R4S Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK2-2 JAK2_HUMAN 5HEZA 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZB 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZD 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7UYWA 2.51 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV0 Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6BBVA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai D7D Type1 843 - 1131 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6X8EA 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai UWP Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6X8EB 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai UWP Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7LL5A 1.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai Y5G Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai MI1 Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai MI1 Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4P7EA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2HB Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4P7EB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2HB Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E62A 1.922 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B1 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E63A 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B2 Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E64A 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B3 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3KRRA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai DQX Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3LPBA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NVB Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3LPBB 2.0 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai NVB Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6A 2.06 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 7GV Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6B 2.06 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 7GV Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ7A 2.1 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 7GT Type1 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ7B 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7GT Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7LL4A 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai Y5D Type1 839 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7REEA 1.38 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 4LY Type1 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4D0WA 1.77 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai VVQ Type1 839 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4D0XA 1.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 953 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5AEPA 1.95 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai QUP Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDA 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDB 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 15V Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 15V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4IVAA 1.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1J5 Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 1M3 Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9B 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1M3 Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3Q32A 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai J2I Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3Q32B 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_ooiai APEdist_aaai J2I Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF8A 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50V Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF8B 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 50V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4AQCA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 88A Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4AQCB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 88A Type1 836 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F08A 2.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F08B 2.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F09A 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAK Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4GFMA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 840 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3RVGA 2.498 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 17P Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLC 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLD 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8A 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3JW Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8B 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3JW Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNBA 2.19 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6P Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNBB 2.19 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6P Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNEA 2.32 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2TA Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNEB 2.32 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 2TA Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNFA 2.06 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNFB 2.06 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao R6S Type1 841 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNGA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6M Type1 841 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNGB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_ioiai APEdist_aaai R6M Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNHA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai XZS Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNHB 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao XZS Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIA 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R61 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIB 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao R61 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5S Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKC 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKD 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLC 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 5W2 Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLD 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 5W2 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNMA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5Y Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNMB 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5Y Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3A 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3B 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNB 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNC 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSND 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTNA 1.83 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai RXT Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTOA 1.74 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3JW Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTPA 2.5 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai U8P Type1 844 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTQA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_nniai APEdist_aaao U8J Type1 849 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZA 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZB 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT0 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OB 2.2 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT0 Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XA 1.97 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XB 1.97 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3IO7A 2.6 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1P5 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3IOKA 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1P6 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9A 1.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9B 1.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXCA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S4R Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXCB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai S4R Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXHA 1.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai C87 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPVA 1.7 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6T3 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPWA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPWB 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMA 2.65 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4OK Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMB 2.65 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4OK Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF4A 2.38 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50Y Type1 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF4B 2.38 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 50Y Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF5A 2.45 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaao 50W Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF5B 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50W Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6A 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50O Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6B 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50O Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DA 2.22 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DB 2.22 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QA 1.948 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QB 1.948 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2XA4A 2.04 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AZ5 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2XA4B 2.04 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AZ5 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMA 2.51 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai F9J Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMB 2.51 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai F9J Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C61A 2.45 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai LMM Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C61B 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LMM Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C62A 2.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai XWW Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C62B 2.75 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai XWW Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZC 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Type1, Allosteric 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK3-2 JAK3_HUMAN 7C3NA 1.98 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai FHX Type1 814 - 1102 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3LXKA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 815 - 1098 0 None C1048S Tyrosine-protein kinase JAK3
TYR LYN LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn
TYR MET MET_HUMAN 4IWDA 1.99 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AME, 1JC Allosteric, Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3Q6WA 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai Q6W Type1 1050 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3R7OA 2.3 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai M61 Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KVTA 2.45 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai YMX Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6IQNB 2.54 Inactive DFGin‑ABAminus out-out none-none TYR APEdihe_nniai APEdist_aaai AQ6 Type1 502 - 788 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4YNEA 2.023 Inactive DFGin‑ABAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai 4EK Type1 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJA 2.75 Inactive DFGin‑ABAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJC 2.75 Inactive DFGin‑ABAminus in-out none-none TYR APEdihe_niiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKNA 2.7 Inactive DFGin‑ABAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 794 0 None G595R High affinity nerve growth factor receptor
TYR PTK2 FAK1_HUMAN 9SDIA 2.53 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao A1JNJ Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 3PXKA 1.79 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PXK Type1 415 - 687 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 3PXKB 1.79 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nniai APEdist_aaai PXK Type1 414 - 687 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YT6A 1.537 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YT6B 1.537 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_niiai APEdist_aaai PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVSA 1.81 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai PVT Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVYA 1.918 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai P1E Type1 412 - 686 0 None None Focal adhesion kinase 1
TYR ROS1 ROS1_HUMAN 3ZBFA 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_nniai APEdist_aaao VGH Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 4UXLA 2.4 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_ooiai APEdist_aaao 5P8 Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR TNK2 ACK1_HUMAN 1U54A 2.8 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ACP ATPlike 115 - 390 0 PTR284 None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4HZRA 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4HZRB 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 118 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 1U46A 2.0 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4EWHA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T77 Type1 117 - 391 0 PTR284 None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4EWHB 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T77 Type1 117 - 390 0 PTR284 None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 7KP6A 1.79 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai WTP Type1 117 - 391 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 7KP6B 1.79 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai WTP Type1 117 - 391 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 6VQMA 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R7P Type1 117 - 390 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8FE9A 3.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WTP Type1 117 - 390 0 None K161Q Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 4ID7A 3.0 Inactive DFGin‑ABAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 1G0 Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 3EQRA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T74 Type1.5_Back 117 - 392 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 3EQRB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T74 Type1.5_Back 117 - 390 0 None None Activated CDC42 kinase 1
TYR TYK2-2 TYK2_HUMAN 7UYRA 2.15 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai OVI Type1 890 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 4PY1A 2.16 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 2YK Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6DBKA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai G5D Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6DBMA 2.368 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai G4J Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6VNSA 2.09 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R5D Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6VNVA 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4Y Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6VNXA 2.18 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4V Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6VNYA 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4S Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6X8FA 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWP Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6X8FC 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWP Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6X8GA 2.21 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWM Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 3LXNA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 888 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 4GJ2A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XH Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 4GJ3A 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XP Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 5WALA 2.45 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 9ZS Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2

All / ABAminus / All

Total number of chains: 1015
Active chains: 1
Total number of genes: 111
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1015 100.0% AF-Q504Y2-K3A
All chains
No PyMOL session because the query has >1000 chains
Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK TWITCHIN Q16980_APLCA 1KOBA 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 17 - 368 0 None None Twitchin-like protein Aplysia californica
CAMK TWITCHIN Q16980_APLCA 1KOBB 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 17 - 368 0 None None Twitchin-like protein Aplysia californica
STE MKK5 M2K5_ARATH 7XBRA 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 63 - 328 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRC 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 64 - 329 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRD 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 329 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRF 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 64 - 327 0 SEP66,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRH 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 329 0 SEP66,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8A 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 273 - 576 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8D 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 583 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8H 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 580 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
OTHER YABT PKN1_BACSU 6G4JA 1.599 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase YabT Bacillus subtilis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPA 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPB 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC GRK2 ARBK1_BOVIN 1YM7B 4.5 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 29 - 656 0 None S670A Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPBG 3.07 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPCG 3.07 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPDG 2.81 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK5 GRK5_BOVIN 4WNKA 2.42 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 453 Type1.5_Front 24 - 541 0 None None G protein-coupled receptor kinase 5 Bos taurus
AGC PRKACA KAPCA_BOVIN 2GNIA 2.27 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 11 - 351 0 SEP11,TPO198,SEP339 L50I,V124M,E128D,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1STCE 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 16 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3ZO2A 1.98 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 15I Type1 8 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3ZO3A 2.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QNI Type1 12 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 5VI9A 1.95 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9D4 Type1 15 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 5VIBA 2.37 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9D1 Type1 19 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1SZMB 2.5 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii BI4 Type1 15 - 351 0 SEP140,TPO198,SEP339 V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4AXAA 1.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKD Type1 15 - 351 0 TPO198,SEP339 V105T,V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C34A 1.78 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 11 - 351 0 SEP11,SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C37A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z21 Type1 14 - 351 0 SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 2GNHA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52, H52 Type1, Allosteric 11 - 351 0 SEP11,TPO198,SEP339 L50I,V124M,E128D,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC ROCK2 ROCK2_BOVIN 2F2UA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii M77 Type1 27 - 417 0 None None Rho-associated protein kinase 2 Bos taurus
AGC ROCK2 ROCK2_BOVIN 2H9VA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y27 Type1 25 - 417 0 None None Rho-associated protein kinase 2 Bos taurus
CAMK TWITCHIN UNC22_CAEEL 3UTOB 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo P33 Allosteric 6112 - 6675 0 None None Twitchin Caenorhabditis elegans
CAMK TWITCHIN UNC22_CAEEL 1KOAA 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 6234 - 6680 0 None None Twitchin Caenorhabditis elegans
CAMK TWITCHIN UNC22_CAEEL 3UTOA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 6112 - 6675 0 None None Twitchin Caenorhabditis elegans
CMGC CDK7 G0SFC6_CHATD 6Z3UB 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 78 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
CMGC CDK7 G0SFC6_CHATD 6Z3UE 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 77 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
AGC PRKACA KAPCA_CRIGR 5OUAA 1.67 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OUSA 2.21 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5NW8A 2.086 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCPA 1.433 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCRA 1.565 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6TX Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCTA 1.615 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6TY Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCUA 1.579 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQP Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M6VA 1.418 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M6YA 1.367 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KB Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M71A 1.488 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7K7 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M75A 1.538 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9K6 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5N1DA 1.609 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8FZ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5N3DA 1.77 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8NE Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5O0EA 1.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5O5MA 1.583 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 10 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OK3A 1.588 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OL3A 1.58 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OT3A 2.04 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 13 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OTGA 1.73 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OUCA 1.46 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EGWA 1.74 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 14 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EH3A 1.95 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B4Z Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERTA 1.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BVZ Type1 14 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERWA 1.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2AA 1.75 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2CA 1.82 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2DA 1.91 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 9 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2HA 1.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y0BA 1.71 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1LQ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y2UA 1.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LRT Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7AXWA 1.69 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1SQ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7BAQA 1.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii T82 Type1 12 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIDA 1.496 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QI Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIEA 1.427 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QF Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIFA 1.395 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QL Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIGA 1.553 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QR Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PNSA 1.855 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7W8 Type1 10 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2BA 1.97 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ, 9LQ Type1, Allosteric 5 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 9REKA 1.38 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D8P, D8P, D8P, D8P Type1, Allosteric, Allosteric, Allosteric 12 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CAMK CDPK2 Q5CYL9_CRYPI 2QG5A 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 197 - 465 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK2 Q5CYL9_CRYPI 2QG5D 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 197 - 464 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK2 Q5CYL9_CRYPI 3F3ZA 1.84 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii DRK Type1 201 - 472 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK4-2 Q5CZ29_CRYPI 3HKOA 1.8 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoi ANP ATPlike 126 - 452 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK PLK1 Q6DRK7_DANRE 4J7BD 2.3 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 20 - 311 0 None D162N,E192F Serine/threonine-protein kinase PLK Danio rerio
TKL ROCO4 ROCO4_DICDI 4YZMB 3.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiai APEdist_nioo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
CMGC BSK JNK_DROME 5AWMA 1.79 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 7 - 362 0 None None Stress-activated protein kinase JNK Drosophila melanogaster
TYR PTK2 FAK1_CHICK 4D4VA 2.1 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4YB 1.8 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D5HB 1.75 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D5KB 1.75 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4VB 2.1 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KB8 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 5SWHA 2.5 Inactive DFGin‑ABAminus in-none none-none TYR APEdihe_nnnai APEdist_aaan 71D Type1 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SWHB 2.5 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 71D Type1 255 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC GRK5 GRK5_HUMAN 9CKOA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 1 - 542 0 None None G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9BRKA 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARA Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9BRLA 2.73 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARB Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9BRPA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1ARF Type1 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC PKN1 PKN1_HUMAN 4OTDA 2.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 605 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1 Homo sapiens
AGC PKN1 PKN1_HUMAN 4OTGA 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2V9 Type1 605 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1 Homo sapiens
AGC PRKACA KAPCA_HUMAN 4AE6A 2.1 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4AE6B 2.1 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4AE9A 2.3 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4AE9B 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 7Y1GB 2.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii I5G Type1 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9DC6A 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3I Type1 16 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9DC6B 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A3I Type1 16 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 3AMBA 2.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 4 - 351 0 SEP11,TPO198,SEP339 K48R,L96Q,M121L,V124A,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 8X5LA 2.75 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo RKD Type1 17 - 351 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 8X5LB 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iioo RKD Type1 17 - 334 0 SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE2A 2.95 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 19 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE3A 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE4A 2.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 19 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE4B 2.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCI KPCI_HUMAN 8R3YI 3.68 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 585 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 8R3XA 2.591 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 8R3XB 2.591 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 587 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 6ILZA 3.261 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AFU Type1 254 - 587 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4UA 1.99 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EX6 Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4UB 1.99 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EX6 Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4WA 2.23 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EZJ Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4WB 2.23 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EZJ Allosteric 205 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4TA 2.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PCG, ATP Allosteric, ATPlike 204 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7T4TB 2.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PCG, ATP Allosteric, ATPlike 204 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NDMA 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NCZA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NCZB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NCZC 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NCZD 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NDMB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NDMC 3.3 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 3ND Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3NDMD 3.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNFA 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNFB 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNFC 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNFD 2.45 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4V Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNGA 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNGB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNGC 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNGD 2.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4Y Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNHA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNHB 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNHC 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 5WNHD 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5MC 2.65 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 18 - 417 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5MD 2.65 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 18 - 417 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7QA 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7QB 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oioo No_ligand No_ligand 28 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7QC 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7QD 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7RA 3.33 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 81G Type1 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 5U7RC 3.33 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiio 81G Type1 25 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5PA 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O1V Type1 27 - 417 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5PB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnio O1V Type1 27 - 417 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5PC 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O1V Type1 28 - 416 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6P5PD 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio O1V Type1 26 - 416 0 None F270Y Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8X8YB 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio YEA Type1 29 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8X8ZA 2.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEI Type1 31 - 416 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8X8ZB 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio YEI Type1 29 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8X92A 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEW Type1 29 - 416 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8X92B 2.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_noio YEW Type1 29 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4WOTA 2.93 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4WOTB 2.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4WOTC 2.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3SG Type1 22 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4WOTD 2.93 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nooo 3SG Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 9HFPA 2.92 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IUI Type1 23 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4L6QA 2.79 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1WU Type1 27 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 4L6QB 2.79 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1WU Type1 27 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 4NW5A 1.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2NR Type1 51 - 359 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KA3-1 KS6A3_HUMAN 4NW6A 1.74 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2NS Type1 51 - 359 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4RLPA 2.79 Inactive DFGin‑ABAminus none-none in-out nonTYR APEdihe_aaiii APEdist_nnno 72B Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4L3JA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4L3LA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 7N91A 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 7N91B 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 7N93A 2.74 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 1SK Type1 87 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 7N93B 2.74 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SK Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 3A62A 2.35 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo STU Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 3WE4A 1.995 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 3WF5A 2.099 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ8 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 3WF6A 2.031 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ9 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4L45A 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4L42A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 5FI Type1 84 - 417 0 None S403E,A404E,N405Q,Q406E,V407M,L409R,G410D,T412E,V414I,P416D,S417W Ribosomal protein S6 kinase beta-1 Homo sapiens
AGC RPS6KB1 KS6B1_HUMAN 4L46A 3.01 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 80 - 417 0 TPO412 None Ribosomal protein S6 kinase beta-1 Homo sapiens
CAMK AURKA AURKA_HUMAN 4C3PD 2.69 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nooo ACP ATPlike 125 - 390 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWA 2.7 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWB 2.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 507 - 390 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 8GUWC 2.7 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 506 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DPVA 2.285 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5DN, SKE Allosteric, Type1 127 - 389 0 None T287A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DR6A 2.534 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5E1, SKE Allosteric, Type1 127 - 390 0 None T287A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 2WTWA 3.302 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoo ZZL Type1 128 - 389 0 None L215R,T217E,R220K Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 3E5AA 2.3 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 125 - 389 0 TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 2NP8A 2.25 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn CC3 Type1 127 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4BYIA 2.6 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno FH3 Type1 126 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5ONEA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nooo 9YQ Type1 127 - 391 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DT0A 2.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoo SKE Type1 127 - 390 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 3UODA 2.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiio 0C3 Type1 124 - 389 0 None T287D Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 3UP2A 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 0C8 Type1 124 - 389 0 None T287D Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4DEAA 2.45 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo NHI Type1 124 - 389 0 None T287D Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5AAFA 2.78 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnno NL4 Type1 126 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5AAGA 2.85 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno 6F2 Type1 127 - 388 0 None C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6GRAA 2.6 Inactive DFGin‑ABAminus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn F8Z Type1.5_Front 126 - 389 0 None None Aurora kinase A Homo sapiens
CAMK AURKC AURKC_HUMAN 9ESAAAA 2.8 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 32 - 306 0 None R195A,R196A,K197A Aurora kinase C Homo sapiens
CAMK AURKC AURKC_HUMAN 9ESABBB 2.8 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 32 - 306 0 None R195A,R196A,K197A Aurora kinase C Homo sapiens
CAMK AURKC AURKC_HUMAN 6GR9A 2.25 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 37 - 305 0 TPO39,TPO198 None Aurora kinase C Homo sapiens
CAMK AURKC AURKC_HUMAN 6GR8A 1.75 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii F8Z Type1.5_Front 36 - 303 0 TPO39,TPO198 None Aurora kinase C Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 1WVYA 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi STU Type1 4 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 9INVA 1.61 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi HCC Type1 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 9INWA 1.52 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi A1L2V Type1 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DCLK1 DCLK1_HUMAN 7F3GB 2.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXT Type1 383 - 648 0 None None Serine/threonine-protein kinase DCLK1 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4A 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4B 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4C 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 48 - 351 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4D 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 349 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4E 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4F 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 353 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4G 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4H 3.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 47 - 358 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4I 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 347 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4J 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 350 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4K 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 348 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MAPKAPK2 MAPK2_HUMAN 8XU4L 3.4 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 47 - 354 0 None S216G MAP kinase-activated protein kinase 2 Homo sapiens
CAMK MARK2 MARK2_HUMAN 3IECB 2.2 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 49 - 363 0 None R146W Serine/threonine-protein kinase MARK2 Homo sapiens
CAMK MARK2 MARK2_HUMAN 3IECD 2.2 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 49 - 363 0 None R146W Serine/threonine-protein kinase MARK2 Homo sapiens
CAMK MARK2 MARK2_HUMAN 5EAKB 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo 24R Type1 51 - 363 0 None None Serine/threonine-protein kinase MARK2 Homo sapiens
CAMK MELK MELK_HUMAN 4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 5TX3A 2.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7MY Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MYLK4 MYLK4_HUMAN 2X4FA 2.67 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo 16X Type1 80 - 373 0 None None Myosin light chain kinase family member 4 Homo sapiens
CAMK MYLK4 MYLK4_HUMAN 2X4FB 2.67 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo 16X Type1 81 - 370 0 None None Myosin light chain kinase family member 4 Homo sapiens
CAMK PIM1 PIM1_HUMAN 4RBLA 2.55 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O7 Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 4RC2A 2.096 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3O8 Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 4RC3A 2.338 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3OA Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 4RC4A 2.651 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3OK Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 4I41A 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MIX, MIX Type1, Allosteric 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PLK4 PLK4_HUMAN 9O63A 2.26 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn A1CAD Type1 2 - 266 0 None None Serine/threonine-protein kinase PLK4 Homo sapiens
CAMK PRKAA1 AAPK1_HUMAN 6C9FA 2.924 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii R34, STU Allosteric, Type1 22 - 558 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens
CAMK PRKAA1 AAPK1_HUMAN 7JIJA 5.5 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 5ISOA 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 5ISOC 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 550 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 6B1UC 2.77 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 9 - 552 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CAMK RPS6KA1-2 KS6A1_HUMAN 2WNTA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanin APEdist_oooo No_ligand No_ligand 416 - 708 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK RPS6KA1-2 KS6A1_HUMAN 2WNTB 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 415 - 709 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK RPS6KA1-2 KS6A1_HUMAN 3RNYA 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 418 - 707 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK RPS6KA1-2 KS6A1_HUMAN 3RNYB 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aannn APEdist_oooo No_ligand No_ligand 419 - 708 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CAMK RPS6KA3-2 KS6A3_HUMAN 4D9TA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_oooo 0JG Type1 415 - 713 0 None None Ribosomal protein S6 kinase alpha-3 Homo sapiens
CAMK RPS6KA3-2 KS6A3_HUMAN 4D9UA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_oooo 0JH Type1 408 - 714 0 None K591E Ribosomal protein S6 kinase alpha-3 Homo sapiens
CAMK SIK3 SIK3_HUMAN 8R4VB 1.9 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii XWA Type1 61 - 384 0 TPO221 C121S,C181S,C333S Serine/threonine-protein kinase SIK3 Homo sapiens
CAMK SIK3 SIK3_HUMAN 8R4VC 1.9 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii XWA Type1 61 - 385 0 TPO221 C121S,C181S,C333S Serine/threonine-protein kinase SIK3 Homo sapiens
CAMK STK17A ST17A_HUMAN 7QUEB 2.4 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaini APEdist_oooo F7I Type1 59 - 322 0 None None Serine/threonine-protein kinase 17A Homo sapiens
CAMK STK17A ST17A_HUMAN 7QUFA 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooo F8I Type1 50 - 322 0 None None Serine/threonine-protein kinase 17A Homo sapiens
CAMK STK17A ST17A_HUMAN 7QUFB 2.6 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_oooo F8I Type1 55 - 322 0 None None Serine/threonine-protein kinase 17A Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 6DC0A 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 67 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 6DC0B 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 74 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB2 TRIB2_HUMAN 7UPMA 2.7 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 55 - 312 0 None None Tribbles homolog 2 Homo sapiens
CAMK TTN TITIN_HUMAN 1TKIA 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 1TKIB 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 4JNWA 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32491 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 4JNWB 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iooo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 6YGNA 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 6YGNB 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 8XPZA 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 20 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7QHWAAA 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7QHWCCC 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CGI Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7Q8VA 2.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7Q8WA 2.02 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IO Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTMA 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTMB 2.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F8E Type1 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q8YA 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q8YB 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IV Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q8ZA 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q8ZB 1.57 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IK Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q90A 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 6 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 7Q90B 1.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9IS Type1 7 - 299 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 VRK2 VRK2_HUMAN 5UU1A 2.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZA 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZB 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZC 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZD 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 437 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZE 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 435 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZF 2.6 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU2H 3.13 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVQ Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU4B 3.09 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQL Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU4H 3.09 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii RQL Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU5B 3.134 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii RMF Type1 713 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU5H 3.134 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMF Type1 713 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BU9H 3.51 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RRC Type1 715 - 1038 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUAB 3.193 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVH Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUAE 3.193 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii RVH Type1 715 - 1033 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUAH 3.193 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RVH Type1 715 - 1034 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUCB 3.85 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKO Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUDB 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RP9 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUDH 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RP9 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUEH 3.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RVU Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUIB 3.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RV6 Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUIH 3.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RV6 Type1 715 - 1038 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BULH 3.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RSU Type1 715 - 1034 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUNB 3.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RNF Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUNH 3.08 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RNF Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUOB 3.58 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RLC Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BURE 3.64 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQU Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUSH 3.26 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMX Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUTB 3.25 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RQ5 Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUTH 3.25 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RQ5 Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 7NXKA 3.0 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii UUB Type1 715 - 1040 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 9FMRE 3.9 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii RMF Type1 714 - 1042 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 9FMRH 3.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RMF Type1 714 - 1044 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8BZOA 3.5 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 14 - 297 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5NEVA 2.97 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii 72L Type1 1 - 295 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5NEVC 2.97 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 72L Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK7 CDK7_HUMAN 6XBZJ 2.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 312 0 SEP164 None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 7EGB8 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 7ENC8 4.13 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 13 - 311 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 7LBME 4.8 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 7NVR8 4.5 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 312 0 None None Cyclin-dependent kinase 7 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6KHDC 2.7 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 3NG Type1 150 - 479 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 6UIPB 3.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 136 - 478 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 6UIPC 3.7 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni Q8J Type1 131 - 477 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC GSK3B GSK3B_HUMAN 6Y9SA 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 6Y9SB 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC HIPK3 HIPK3_HUMAN 7O7JA 2.81 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6ZV Type1 184 - 551 0 PTR359 None Homeodomain-interacting protein kinase 3 Homo sapiens
CMGC MAPK1 MK01_HUMAN 8PVUE 3.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 24 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 1WZYA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoio APEdist_oioo F29 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 1TVOA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FRZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4Z9LA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno ANP, 880 Allosteric, Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4KKGA 2.4 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3FI2A 2.28 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JK1 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3FV8A 2.28 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno JK3 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2B1PA 1.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AIZ Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2R9SA 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2R9SB 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2EXCX 2.75 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno JNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3OY1A 1.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 589 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3RTPA 2.4 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 34I Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2O2UA 2.45 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 738 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2WAJA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SNB Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2ZDTA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo 46C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2ZDUA 2.5 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 446 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3FI3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno JK2 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3KVXA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnno FMY Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3V6RA 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3V6RB 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3V6SA 2.97 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3V6SB 2.97 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 1PMNA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 984 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 1PMUA 2.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iooo 9HP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7ORFA 1.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0G3 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2P33A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo J07 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3CGFA 3.0 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo JNF Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3CGOA 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo JNO Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3G90X 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J72 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3G9LX 2.2 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno J67 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3G9NA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J88 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4KKHA 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 1RQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4W4VA 2.01 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3H8 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4W4WA 1.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HJ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4W4XA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HN Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4W4YA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4Y5HA 2.055 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 519 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4X21A 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4X21B 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EKDA 2.1 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno B9K Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHC 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHD 1.76 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4WHZA 1.79 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 3NL Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3TTIA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo KBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7KSIA 1.726 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3S Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7KSJA 2.06 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3Y Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7KSKA 1.84 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_onoo X3V Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7S1NA 2.11 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 86C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7YL1A 2.48 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo J6F Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8ENJA 2.81 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo WNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8VNXA 2.0 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8VO4A 2.07 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHE Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8VTFA 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 7OREA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0EI, 0EI Type1, Type1 44 - 402 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2O0UA 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 3DA6A 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo BZ9 Type1.5_Front 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 4U79A 2.23 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3EL Type1.5_Front 44 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK11 MK11_HUMAN 3GC9B 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo B45 Type1 2 - 349 0 None C119S,C162S Mitogen-activated protein kinase 11 Homo sapiens
CMGC MAPK11 MK11_HUMAN 3GC8A 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_iooo B45 Type1 3 - 349 0 None C162S Mitogen-activated protein kinase 11 Homo sapiens
CMGC MAPK11 MK11_HUMAN 3GC8B 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo B45 Type1 4 - 349 0 None C162S Mitogen-activated protein kinase 11 Homo sapiens
CMGC MAPK12 MK12_HUMAN 7CGAB 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK12 MK12_HUMAN 7CGAC 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK12 MK12_HUMAN 7CGAD 3.15 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 9 - 353 0 None None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK8 MK08_HUMAN 6ZR5A 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 3 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 6ZR5B 2.699 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioo ANP ATPlike 4 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 2XRWA 1.33 Inactive DFGin‑ABAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 2 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 2XS0A 2.6 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoo APEdist_nnnn ANP ATPlike 6 - 365 0 None T183V,Y185F Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9A 2.34 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9C 2.34 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii ANP ATPlike 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4UX9D 2.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oioo ANP ATPlike 9 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8R5EA 1.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP, Y6K ATPlike, Allosteric 5 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 1UKHA 2.35 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4YR8A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4YR8C 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 10 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4YR8E 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 7 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4YR8F 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 10 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 6F5EB 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 7 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8X5MA 2.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno Y4O Type1 7 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT8A 2.78 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nioo A3O Type1 7 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT8B 2.78 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_iioo A3O Type1 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT8C 2.78 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo A3O Type1 7 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT9A 2.7 Inactive DFGin‑ABAminus out-in out-out nonTYR APEdihe_aaooi APEdist_iooo DVI Type1 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT9B 2.7 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nioo DVI Type1 7 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PT9C 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo DVI Type1 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PTAA 2.41 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo CIF Type1 8 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PTAB 2.41 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo CIF Type1 7 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 8PTAC 2.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo CIF Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 1UKIA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 537 Type1 9 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4E73A 2.27 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 0NR Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4G1WA 2.45 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn G1W Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4HYSA 2.415 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1BJ Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4HYUA 2.152 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1BK Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4IZYA 2.3 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 1J2 Type1 8 - 361 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 3PZEA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno CFK Type1 7 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4L7FA 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo 1V5 Type1 7 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 3ELJA 1.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo GS7 Type1 7 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4AWIA 1.91 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo AQ2 Type1 8 - 364 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 5LW1B 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 5LW1E 3.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 5LW1H 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ADN Type1 8 - 362 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK8 MK08_HUMAN 4QTDA 1.5 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo 38Z, ANP Type1, Allosteric 6 - 363 0 None None Mitogen-activated protein kinase 8 Homo sapiens
CMGC MAPK9 MK09_HUMAN 7N8TA 1.69 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iioo AMP ATPlike 10 - 364 0 None None Mitogen-activated protein kinase 9 Homo sapiens
CMGC MAPK9 MK09_HUMAN 8ELCA 2.072 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo Y56 Type1 9 - 363 0 None None Mitogen-activated protein kinase 9 Homo sapiens
CMGC MAPK9 MK09_HUMAN 3E7OA 2.14 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiio APEdist_oooo 35F Type1 9 - 361 0 None C177S,C222S,K250A,K251A,K265A,K270A Mitogen-activated protein kinase 9 Homo sapiens
CMGC MAPK9 MK09_HUMAN 3E7OB 2.14 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 35F Type1 8 - 362 0 None C177S,C222S,K250A,K251A,K265A,K270A Mitogen-activated protein kinase 9 Homo sapiens
CMGC SRPK1 SRPK1_HUMAN 5MY8A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXZ Type1 64 - 655 0 None None SRSF protein kinase 1 Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3OA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3OB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3RA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3RB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5IKWA 2.41 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6BU Type1 42 - 338 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A1AB 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo No_ligand No_ligand 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 8QELB 2.451 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo UH3 Type1 258 - 541 0 TPO446 None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER ERN1 ERN1_HUMAN 4Z7HB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioi 4L5 Type1 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER GAK GAK_HUMAN 4O38A 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 25 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4O38B 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 26 - 337 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y7ZA 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y7ZB 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y80A 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo IRE, IRE Type1, Allosteric 25 - 332 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K3A -1.0 Active DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC Homo sapiens
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3CEKA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3DBQA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 515 - 796 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2ZMCA 3.14 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6GVJA 2.41 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 515 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5LJJA 3.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AD5 Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5MRBA 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EH0A 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5NW Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6H3KA 2.48 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn FMW Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4JS8A 1.94 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo 1PF Type1 515 - 793 0 TPO675,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4JT3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1PH Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4O6LA 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4O6LB 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4ZEGA 2.33 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 052 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CILA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo FZR Type1 515 - 795 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CHNA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo FZL Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CJAA 2.49 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo G0U Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CLHA 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo G5C Type1 516 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TN9A 2.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo NN5 Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNCA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo O23 Type1 516 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6N6OA 2.6 Inactive DFGin‑ABAminus out-out out-none nonTYR APEdihe_aanni APEdist_nnnn KE7 Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BHZA 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0B Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI0A 2.84 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0W Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI1A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO6 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI2A 3.11 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO8 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4EA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 4T9 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4FA 2.36 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 7CE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4GA 2.65 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaono APEdist_nnoo 7RO Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4HA 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 7RO Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4IA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X20 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4JA 2.5 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo X21 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CV8A 3.0 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno 3D7 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CV9A 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo W2K Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CVAA 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo WBI Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP0A 2.15 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo AU5 Type1 519 - 795 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP1A 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo O38 Type1 519 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP2A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno PWU Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHLA 2.66 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo 0SQ Type1 519 - 796 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHOA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O1 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHYA 2.26 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O4 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI2A 2.67 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5O7 Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI6A 2.01 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5OQ Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI8A 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5OE Type1 519 - 753 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N87A 2.29 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo N66 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP6A 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo PWU Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5O91A 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 796 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6B4WA 2.9 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnoo CQ7 Type1 515 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3VQUA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno O22 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WYXA 2.9 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O38 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WYYA 3.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O17 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N7VA 2.52 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaono APEdist_oooo 8PT Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N84A 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo 8Q5 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N93A 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo 8QE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NA0A 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo 8QZ Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3HMOA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 514 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3HMPA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo CX4 Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP3A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_iooo AU5 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP4A 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo O38 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2ZMDA 2.88 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_oooo 537 Type1 516 - 795 0 None T686A Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7LQDA 1.95 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YB4, TOE Type1, Allosteric 519 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP5A 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7RO, 1KA Type1, Type1 519 - 794 0 None S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNBA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno 8QW Type1.5_Front 517 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N9SA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo 8QW Type1.5_Front 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER WEE1 WEE1_HUMAN 9D0SA 1.64 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1R Type1 292 - 574 0 None None Wee1-like protein kinase Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6QFLA 2.2 Inactive DFGin‑ABAminus na-na in-out nonTYR APEdihe_aaiai APEdist_nnoi No_ligand No_ligand 102 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6QFTA 2.7 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aanai APEdist_nnnn J0B Type1 102 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6QG4A 2.3 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aannn APEdist_nnnn J0E Type1 111 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6QG7A 2.1 Inactive DFGin‑ABAminus na-na in-out nonTYR APEdihe_aaiai APEdist_nnoi 6HL Type1 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6QHOA 2.7 Inactive DFGin‑ABAminus na-na in-none nonTYR APEdihe_aannn APEdist_nnnn J3H Type1 111 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4IDTA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi T28 Type1 333 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6NFYA 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi B49 Type1 10 - 292 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6NFYB 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oioi B49 Type1 10 - 292 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9N48B 1.85 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BV1 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK4 PAK4_HUMAN 4XBRA 2.94 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 177 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE STK10 STK10_HUMAN 4USEA 2.65 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aanio APEdist_nnnn R09 Type1 24 - 316 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STE STK10 STK10_HUMAN 4USEB 2.65 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aanio APEdist_nnnn R09 Type1 24 - 316 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STE STK3 STK3_HUMAN 5DH3B 2.468 Inactive DFGin‑ABAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BS Type1 18 - 302 0 TPO174,TPO180 None Serine/threonine-protein kinase 3 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T6DB 2.56 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MM8 Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6T6DC 2.56 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii MM8 Type1 205 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCA 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 205 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCB 2.67 Inactive DFGin‑ABAminus in-out in-none nonTYR APEdihe_aaiii APEdist_niii H8H Type1 203 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCC 2.67 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi H8H Type1 201 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6ZGCD 2.67 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H8H Type1 203 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL BRAF BRAF_HUMAN 4H58B 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PRFA 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioo APEdist_nnno FP3 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E8YA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 240 - 541 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TYR ALK ALK_HUMAN 3LCTA 2.1 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaao ADP ATPlike 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4TT7A 2.1 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao COM, COM Allosteric, Allosteric 1095 - 1400 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7JY4A 2.42 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao W47, W47 Allosteric, Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2YHVA 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4ANLA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1094 - 1402 0 None G1269A ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FNWA 1.75 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1084 - 1405 0 None C1097S,F1174L ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FNXA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1093 - 1404 0 None C1097S,R1275Q ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 6CDTA 1.8 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1093 - 1400 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2YJSA 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 1094 - 1402 0 None C1156Y ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 3L9PA 1.8 Inactive DFGin‑ABAminus in-none out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4ANSA 1.85 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None L1196M,G1269A ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2YFXA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CLJA 1.66 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 5P8 Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CD0A 2.23 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4ANQA 1.76 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None G1269A ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5AA9A 1.93 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None L1198F ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5AAAA 1.73 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1401 0 None L1198F ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5AA8A 1.86 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5AABA 2.2 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 6MX8A 1.96 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 6GY Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2XB7A 2.5 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao GUI Type1 1095 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2XBAA 1.95 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 571 Type1 1095 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5FTOA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai YMX Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5FTQA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai U4W Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 8ARJA 1.645 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao NRR Type1 1103 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 6E0RA 2.303 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_niiai APEdist_aaai HKJ Type1 1099 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 6EBWA 2.455 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai J3Y Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7JYRA 2.32 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VTA Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7JYSA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao VTD Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7JYTA 2.0 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VRM Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 2XP2A 1.9 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_niiai APEdist_aaao VGH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CCBA 2.03 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai OFG Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CCUA 2.0 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWF Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CLIA 2.05 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 5P8 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CMOA 2.05 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai YPW Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CMTA 1.73 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai GWH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CMUA 1.8 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai IV7 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CNHA 1.9 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_niiai APEdist_aaai 3U9 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CTBA 1.79 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao KVC Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CTCA 2.03 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai J99 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5KZ0A 2.3 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 6YL Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7R7KA 1.831 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai 25J Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7R7RA 1.935 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaai AWJ Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FNZA 2.6 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_oiiai APEdist_aaai NZF Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5IUIA 1.88 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 45Q Type1 1089 - 1400 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FODA 2.0 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0UV Type1 1085 - 1405 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 3AOXA 1.75 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai EMH Type1 1086 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5A9UA 1.6 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 5P8 Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5AACA 1.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao VGH Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 7BTTA 1.86 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao F8R Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FOBA 1.9 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0US Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4FOCA 1.7 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 0UU Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4Z55A 1.55 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 4LO Type1 1093 - 1399 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 3LCSA 1.95 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao STU Type1 1096 - 1399 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4MKCA 2.01 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 4MK Type1 1093 - 1401 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 9GBEA 1.58 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao A1IJ8 Type1 1086 - 1401 0 None L1196M,G1202R ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4CNHB 1.9 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 3U9, 3U9 Type1, Allosteric 1093 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 4JOAA 2.7 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_oiiai APEdist_aaao 3DK Type1.5_Front 1107 - 1398 0 None S1281G ALK tyrosine kinase receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3IKAA 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7ER2A 2.662 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAU Type1 697 - 1018 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9XU9A 2.84 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1E1C Type1 696 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8KFQA 3.22 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai VUZ Type1 697 - 1018 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 697 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 4TRLA 2.452 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 599 - 875 0 PTR772 None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJBA 2.8 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 591 - 965 0 None S897E,S901E Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK0A 1.597 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 91E Type1 602 - 894 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK8A 1.761 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 90Z Type1 605 - 894 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNHA 1.379 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 602 - 889 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNHB 1.379 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_niiai APEdist_aaao DXK Type1 602 - 882 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK3A 1.586 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 92Q Type1.5_Back 601 - 888 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8QQYA 1.8 Inactive DFGin‑ABAminus in-in out-none TYR APEdihe_niiai APEdist_aaai WT3 Type1.5_Back 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR IGF1R IGF1R_HUMAN 1K3AA 2.1 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 988 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 2ZM3A 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 2ZM3B 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 2ZM3C 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 2ZM3D 2.5 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LVPA 3.0 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai PDR Type1 989 - 1286 0 None None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LVPB 3.0 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LVPC 3.0 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_oiiai APEdist_aaai PDR Type1 987 - 1286 0 None None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PA 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PB 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PC 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PD 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PE 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PF 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PG 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PH 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PI 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PJ 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PK 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PL 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PM 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PR 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PS 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3F5PT 2.9 Inactive DFGin‑ABAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor Homo sapiens
TYR INSR INSR_HUMAN 2AUHA 3.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1011 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 2B4SB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 2B4SD 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 3BU6A 1.95 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5KHWA 2.47 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4LE 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 3EYGA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 3EYHA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5E1EB 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 5JG Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6AAHA 1.83 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6AAHB 1.83 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6TPEA 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NTW Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6TPEB 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NTW Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6TPFA 2.31 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai NTQ Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6TPFB 2.31 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai NTQ Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6GGHA 1.7 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai EYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6GGHB 1.7 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai EYQ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6ELRA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai BFK Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6ELRB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai BFK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6SM8B 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKT Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6SMBA 2.04 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6SMBB 2.04 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4LA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4LB 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4LD 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4NA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NL Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E4NB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NL Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E5WA 1.86 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4E5WB 1.86 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0NT Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZA 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 858 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZB 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZC 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZD 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EI4A 2.22 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0Q2 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EI4B 2.22 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0Q2 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4FK6A 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0UJ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4FK6B 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0UJ Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4I5CA 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai C5I Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4I5CB 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai C5I Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVBA 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J5 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVBB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVCA 2.35 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J6 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVCB 2.35 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1J6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVDA 1.93 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 15T Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4IVDB 1.93 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 15T Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4K6ZA 2.73 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q3 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4K77A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4K77B 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1Q4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5HX8A 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 66P Type1 855 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5HX8B 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 66P Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5WO4A 1.84 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai B7V Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5WO4B 1.84 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai B7V Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6HZUA 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai GYQ Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6HZUB 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai GYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N77A 1.64 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KEJ Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N77B 1.64 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KEJ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N78A 1.83 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEP Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N79A 2.27 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KES Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7BA 1.81 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEY Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7CA 1.69 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7CB 1.69 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7DA 1.78 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KF4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSBA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSBB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSCA 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSCB 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSDA 1.76 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSDB 1.76 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSEA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSEB 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSHA 1.71 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6RSHB 1.71 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6SM8A 1.85 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai LKT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 8S85A 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 8S85B 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7AA 1.33 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEV Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6N7AB 1.33 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai KEV Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 5KHXA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TE Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6BBUA 2.08 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai D7D Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6DBNA 2.48 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai G4J Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6W8LA 2.11 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R4S Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZA 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZB 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZD 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7UYWA 2.51 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV0 Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6BBVA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai D7D Type1 843 - 1131 0 None None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6X8EA 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai UWP Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6X8EB 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai UWP Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7LL5A 1.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai Y5G Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 2B7AA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 2B7AB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai IZA Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3FUPA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai MI1 Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3FUPB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai MI1 Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4P7EA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2HB Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4P7EB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2HB Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3E62A 1.922 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B1 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3E63A 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B2 Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3E64A 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5B3 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3KRRA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai DQX Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3LPBA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai NVB Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3LPBB 2.0 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai NVB Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ6A 2.06 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 7GV Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ6B 2.06 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 7GV Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ7A 2.1 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 7GT Type1 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ7B 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 7GT Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7LL4A 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai Y5D Type1 839 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7REEA 1.38 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 4LY Type1 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4D0WA 1.77 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai VVQ Type1 839 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4D0XA 1.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 953 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5AEPA 1.95 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai QUP Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3TJCA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3TJCB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3TJDA 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3TJDB 2.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4HGEA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 15V Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4HGEB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 15V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4IVAA 1.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1J5 Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4JI9A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 1M3 Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4JI9B 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1M3 Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3Q32A 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai J2I Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3Q32B 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_ooiai APEdist_aaai J2I Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF8A 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50V Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF8B 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 50V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4AQCA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 88A Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4AQCB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 88A Type1 836 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4F08A 2.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4F08B 2.82 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4F09A 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAK Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4GFMA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 840 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3RVGA 2.498 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 17P Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VGLA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VGLB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VGLC 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VGLD 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VN8A 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3JW Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VN8B 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 3JW Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNBA 2.19 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6P Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNBB 2.19 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6P Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNCA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNCB 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNEA 2.32 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2TA Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNEB 2.32 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 2TA Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNFA 2.06 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNFB 2.06 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao R6S Type1 841 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNGA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6M Type1 841 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNGB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_ioiai APEdist_aaai R6M Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNHA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai XZS Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNHB 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao XZS Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNIA 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R61 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNIB 2.1 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao R61 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNJA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNJB 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5S Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNKA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNKB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNKC 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNKD 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNLA 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNLB 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNLC 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 5W2 Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNLD 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 5W2 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNMA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5Y Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VNMB 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R5Y Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VS3A 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VS3B 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R6V Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VSNA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VSNB 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VSNC 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6VSND 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6WTNA 1.83 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai RXT Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6WTOA 1.74 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3JW Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6WTPA 2.5 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai U8P Type1 844 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6WTQA 1.8 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_nniai APEdist_aaao U8J Type1 849 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G6ZA 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G6ZB 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G8OA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT0 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G8OB 2.2 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT0 Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G8XA 1.97 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G8XB 1.97 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3IO7A 2.6 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1P5 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3IOKA 2.1 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1P6 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BX9A 1.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BX9B 1.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BXCA 1.9 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai S4R Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BXCB 1.9 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai S4R Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BXHA 1.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai C87 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BPVA 1.7 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 6T3 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BPWA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8BPWB 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4ZIMA 2.65 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4OK Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4ZIMB 2.65 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4OK Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF4A 2.38 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50Y Type1 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF4B 2.38 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 50Y Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF5A 2.45 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaao 50W Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF5B 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50W Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF6A 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50O Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5CF6B 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 50O Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4E6DA 2.22 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4E6DB 2.22 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4E6QA 1.948 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4E6QB 1.948 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 2XA4A 2.04 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AZ5 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 2XA4B 2.04 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AZ5 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3ZMMA 2.51 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai F9J Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3ZMMB 2.51 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai F9J Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4C61A 2.45 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai LMM Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4C61B 2.45 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LMM Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4C62A 2.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai XWW Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4C62B 2.75 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai XWW Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZC 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Type1, Allosteric 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 7C3NA 1.98 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai FHX Type1 814 - 1102 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3LXKA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 815 - 1098 0 None C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR LYN LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Homo sapiens
TYR MET MET_HUMAN 4IWDA 1.99 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AME, 1JC Allosteric, Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3Q6WA 1.75 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai Q6W Type1 1050 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3R7OA 2.3 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai M61 Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KVTA 2.45 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai YMX Type1 501 - 787 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6IQNB 2.54 Inactive DFGin‑ABAminus out-out none-none TYR APEdihe_nniai APEdist_aaai AQ6 Type1 502 - 788 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4YNEA 2.023 Inactive DFGin‑ABAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai 4EK Type1 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4AOJA 2.75 Inactive DFGin‑ABAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4AOJC 2.75 Inactive DFGin‑ABAminus in-out none-none TYR APEdihe_niiai APEdist_aaai V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 7VKNA 2.7 Inactive DFGin‑ABAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 794 0 None G595R High affinity nerve growth factor receptor Homo sapiens
TYR PTK2 FAK1_HUMAN 9SDIA 2.53 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao A1JNJ Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 3PXKA 1.79 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PXK Type1 415 - 687 0 None P410G Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 3PXKB 1.79 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nniai APEdist_aaai PXK Type1 414 - 687 0 None P410G Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 6YT6A 1.537 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_nniai APEdist_aaao PKE Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 6YT6B 1.537 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_niiai APEdist_aaai PKE Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 6YVSA 1.81 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai PVT Type1 414 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 6YVYA 1.918 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai P1E Type1 412 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
TYR ROS1 ROS1_HUMAN 3ZBFA 2.2 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_nniai APEdist_aaao VGH Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS Homo sapiens
TYR ROS1 ROS1_HUMAN 4UXLA 2.4 Inactive DFGin‑ABAminus in-out in-out TYR APEdihe_ooiai APEdist_aaao 5P8 Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS Homo sapiens
TYR TNK2 ACK1_HUMAN 1U54A 2.8 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai ACP ATPlike 115 - 390 0 PTR284 None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZRA 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4HZRB 1.31 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 118 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 1U46A 2.0 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4EWHA 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T77 Type1 117 - 391 0 PTR284 None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4EWHB 2.5 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T77 Type1 117 - 390 0 PTR284 None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 7KP6A 1.79 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai WTP Type1 117 - 391 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 7KP6B 1.79 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai WTP Type1 117 - 391 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 6VQMA 2.87 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R7P Type1 117 - 390 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8FE9A 3.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai WTP Type1 117 - 390 0 None K161Q Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 4ID7A 3.0 Inactive DFGin‑ABAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 1G0 Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 3EQRA 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T74 Type1.5_Back 117 - 392 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 3EQRB 2.0 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai T74 Type1.5_Back 117 - 390 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 7UYRA 2.15 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_niiai APEdist_aaai OVI Type1 890 - 1177 0 PTR1054,PTR1055 None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 4PY1A 2.16 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 2YK Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6DBKA 2.0 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai G5D Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6DBMA 2.368 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai G4J Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6VNSA 2.09 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R5D Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6VNVA 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4Y Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6VNXA 2.18 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4V Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6VNYA 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4S Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6X8FA 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWP Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6X8FC 2.15 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWP Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6X8GA 2.21 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai UWM Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,A1016S,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 3LXNA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai MI1 Type1 888 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 4GJ2A 2.4 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XH Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 4GJ3A 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0XP Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 5WALA 2.45 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 9ZS Type1 890 - 1176 0 None C936A,Q969A,E971A,K972A,D1023N,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
OTHER BUD32 KAE1B_METJA 8UNKB 2.91 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 356 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 9D85B 3.59 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
AGC PRKACA KAPCA_MOUSE 6MM6C 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM6E 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7A 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7D 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM8C 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKND 2.75 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKOE 2.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKPE 2.85 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 17 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTB 3.5 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNC 2.75 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNF 2.75 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNH 2.75 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3TNPC 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3TNPF 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4WBBB 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6QC 2.52 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTSA 2.9 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTSB 2.9 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5X3FB 3.38 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 317 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
CMGC DYRK1A DYR1A_MOUSE 9KRJA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus
CMGC GSK3B GSK3B_MOUSE 5AIRA 2.53 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 7PVUA 2.154 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVIA 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFY Type1 34 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
TYR TYK2-2 TYK2_MOUSE 4E20A 2.6 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MY Type1 885 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus
TYR TYK2-2 TYK2_MOUSE 4E1ZA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MX Type1 884 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 7Q52AAA 2.35 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE, 8ZC Allosteric, Type1 87 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii AXX Type1 74 - 746 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIB 2.4 Inactive DFGin‑ABAminus out-out in-none nonTYR APEdihe_aaiii APEdist_niii AXX Type1 74 - 745 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
CAMK None A0A3P9GXN4_ORYLA 9QJ2A 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 421 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK None A0A3P9GXN4_ORYLA 9QJ2B 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 419 - 763 0 None None Uncharacterized protein Oryzias latipes
OTHER PINK1 PINK1_PEDHC 6EQIC 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 147 - 574 0 SEP202,SEP204,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
AGC PKG KGP_PLAF7 8EM8A 2.54 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii WLK Type1 28 - 817 0 None None cGMP-dependent protein kinase Plasmodium falciparum
CAMK CDPK2 CDPK2_PLAFK 4MVFA 2.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 60 - 511 0 None None Calcium-dependent protein kinase 2 Plasmodium falciparum
AGC PKG KGP_PLAVS 4RZ7A 2.351 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1E8 Type1 1 - 815 0 None None cGMP-dependent protein kinase Plasmodium vivax
AGC PKG KGP_PLAVS 5FETA 3.07 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1TR Type1 2 - 816 0 None None cGMP-dependent protein kinase Plasmodium vivax
AGC PRKACA KAPCA_RAT 3TNQB 3.097 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 18 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4TA 3.4 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiio HTV, STU Allosteric, Type1 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFGA 3.46 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFRA 3.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, 32J Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFSA 3.55 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, 32H Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4UA 3.27 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, HU7 Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4WA 3.35 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, HUG Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
TYR CSK CSK_RAT 1K9AB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 4 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CAMK RAD53 RAD53_YEAST 5XZWA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 15 - 465 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CMGC SSN3 SSN3_YEAST 7KPVA 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 48 - 489 0 None None Meiotic mRNA stability protein kinase SSN3 Saccharomyces cerevisiae
CMGC SSN3 SSN3_YEAST 7KPXA 4.4 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 48 - 489 0 None None Meiotic mRNA stability protein kinase SSN3 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2A 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2B 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSA 3.07 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSB 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 946 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSC 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
OTHER None A0ACD6BAW3_SERSF 5HNVA 1.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1QA 1.602 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1SA 1.45 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ACP ATPlike 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1TA 1.55 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ADP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1RA 1.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo No_ligand No_ligand 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER RNASEL A5H025_PIG 4O1PA 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PB 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PC 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PD 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OA 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OB 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OC 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OD 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER TCUR3610 D1ABX1_THECD 7WJ6A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 222 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 220 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 222 - 469 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 221 - 467 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
CAMK AURKBA AUKBA_XENLA 4C2WA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2WB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFXA 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 86 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFXB 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKB 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1 81 - 356 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5K3YA 1.6 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6Q4 Type1 88 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5K3YB 1.6 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6Q4 Type1 79 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFYA 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii H1N Type1 86 - 357 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFYB 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii H1N Type1 78 - 357 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGOA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD5 Type1 87 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGOB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD5 Type1 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGPA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD6 Type1 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGPB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD6 Type1 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 3ZTXA 1.95 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZTX Type1 87 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 3ZTXB 1.95 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZTX Type1 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4B8MA 1.85 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 87 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4B8MB 1.85 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXB 1.86 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Back 77 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXA 1.86 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Front 87 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2VA 1.49 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJA Type1.5_Front 87 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2VB 1.49 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJA Type1.5_Front 76 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis

All / ABAminus / All

Total number of chains: 192
Active chains: 0
Total number of genes: 40
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 192 100.0% 5M6YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK TWITCHIN Q16980_APLCA 1KOBA 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 17 - 368 0 None None Twitchin-like protein Aplysia californica
CAMK TWITCHIN Q16980_APLCA 1KOBB 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 17 - 368 0 None None Twitchin-like protein Aplysia californica
STE MKK5 M2K5_ARATH 7XBRA 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 63 - 328 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRC 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 64 - 329 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRD 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 329 0 SEP66,TPO83,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRF 3.2 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 64 - 327 0 SEP66,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
STE MKK5 M2K5_ARATH 7XBRH 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 65 - 329 0 SEP66,TPO108,TPO215,SEP221 None Mitogen-activated protein kinase kinase 5 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8A 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 273 - 576 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8D 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 583 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
TKL BAK1 BAK1_ARATH 3TL8H 2.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 274 - 580 0 TPO324,TPO446,TPO449,TPO450 None BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 Arabidopsis thaliana
OTHER YABT PKN1_BACSU 6G4JA 1.599 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase YabT Bacillus subtilis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPA 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPB 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
AGC GRK2 ARBK1_BOVIN 1YM7B 4.5 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 29 - 656 0 None S670A Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPBG 3.07 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPCG 3.07 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK2 ARBK1_BOVIN 8JPDG 2.81 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 659 0 None A292P,R295I,S455D Beta-adrenergic receptor kinase 1 Bos taurus
AGC GRK5 GRK5_BOVIN 4WNKA 2.42 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 453 Type1.5_Front 24 - 541 0 None None G protein-coupled receptor kinase 5 Bos taurus
AGC PRKACA KAPCA_BOVIN 2GNIA 2.27 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 11 - 351 0 SEP11,TPO198,SEP339 L50I,V124M,E128D,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1STCE 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 16 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3ZO2A 1.98 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 15I Type1 8 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3ZO3A 2.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QNI Type1 12 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 5VI9A 1.95 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 9D4 Type1 15 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 5VIBA 2.37 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9D1 Type1 19 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1SZMB 2.5 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii BI4 Type1 15 - 351 0 SEP140,TPO198,SEP339 V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4AXAA 1.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKD Type1 15 - 351 0 TPO198,SEP339 V105T,V124A,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C34A 1.78 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 11 - 351 0 SEP11,SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C37A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z21 Type1 14 - 351 0 SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 2GNHA 2.05 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52, H52 Type1, Allosteric 11 - 351 0 SEP11,TPO198,SEP339 L50I,V124M,E128D,Q182K,T184A cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC ROCK2 ROCK2_BOVIN 2F2UA 2.4 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii M77 Type1 27 - 417 0 None None Rho-associated protein kinase 2 Bos taurus
AGC ROCK2 ROCK2_BOVIN 2H9VA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y27 Type1 25 - 417 0 None None Rho-associated protein kinase 2 Bos taurus
CAMK TWITCHIN UNC22_CAEEL 3UTOB 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo P33 Allosteric 6112 - 6675 0 None None Twitchin Caenorhabditis elegans
CAMK TWITCHIN UNC22_CAEEL 1KOAA 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo No_ligand No_ligand 6234 - 6680 0 None None Twitchin Caenorhabditis elegans
CAMK TWITCHIN UNC22_CAEEL 3UTOA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 6112 - 6675 0 None None Twitchin Caenorhabditis elegans
CMGC CDK7 G0SFC6_CHATD 6Z3UB 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 78 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
CMGC CDK7 G0SFC6_CHATD 6Z3UE 2.6 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 77 - 399 0 None None Protein kinase domain-containing protein Chaetomium thermophilum
AGC PRKACA KAPCA_CRIGR 5OUAA 1.67 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OUSA 2.21 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5NW8A 2.086 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCPA 1.433 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCRA 1.565 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6TX Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCTA 1.615 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6TY Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5LCUA 1.579 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQP Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M6VA 1.418 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M6YA 1.367 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7KB Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M71A 1.488 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7K7 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5M75A 1.538 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9K6 Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5N1DA 1.609 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8FZ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5N3DA 1.77 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8NE Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5O0EA 1.5 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5O5MA 1.583 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 10 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OK3A 1.588 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OL3A 1.58 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OT3A 2.04 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 13 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OTGA 1.73 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 5OUCA 1.46 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EGWA 1.74 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 14 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EH3A 1.95 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B4Z Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERTA 1.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BVZ Type1 14 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ERWA 1.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2AA 1.75 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2CA 1.82 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2DA 1.91 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ Type1 9 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2HA 1.68 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AO8 Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y0BA 1.71 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1LQ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y2UA 1.93 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LRT Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7AXWA 1.69 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1SQ Type1 1 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7BAQA 1.54 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii T82 Type1 12 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIDA 1.496 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QI Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIEA 1.427 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QF Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIFA 1.395 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QL Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PIGA 1.553 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QR Type1 1 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 7PNSA 1.855 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7W8 Type1 10 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6I2BA 1.97 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9LQ, 9LQ Type1, Allosteric 5 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 9REKA 1.38 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D8P, D8P, D8P, D8P Type1, Allosteric, Allosteric, Allosteric 12 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CAMK CDPK2 Q5CYL9_CRYPI 2QG5A 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 197 - 465 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK2 Q5CYL9_CRYPI 2QG5D 2.3 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 197 - 464 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK2 Q5CYL9_CRYPI 3F3ZA 1.84 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii DRK Type1 201 - 472 0 SEP408 None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK CDPK4-2 Q5CZ29_CRYPI 3HKOA 1.8 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nnoi ANP ATPlike 126 - 452 0 None None non-specific serine/threonine protein kinase Cryptosporidium parvum
CAMK PLK1 Q6DRK7_DANRE 4J7BD 2.3 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 20 - 311 0 None D162N,E192F Serine/threonine-protein kinase PLK Danio rerio
TKL ROCO4 ROCO4_DICDI 4YZMB 3.0 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiai APEdist_nioo 4K4 Type1 1019 - 1292 0 None F1107L,F1161L Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
CMGC BSK JNK_DROME 5AWMA 1.79 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ANP ATPlike 7 - 362 0 None None Stress-activated protein kinase JNK Drosophila melanogaster
TYR PTK2 FAK1_CHICK 4D4VA 2.1 Inactive DFGin‑ABAminus in-in none-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4YB 1.8 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D5HB 1.75 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D5KB 1.75 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4SB 2.0 Inactive DFGin‑ABAminus in-out out-none TYR APEdihe_nniai APEdist_aaai BI9 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D4VB 2.1 Inactive DFGin‑ABAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KB8 Type1 415 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 4D58B 1.95 Inactive DFGin‑ABAminus in-out out-out TYR APEdihe_nniai APEdist_aaao BI9 Type1 414 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 5SWHA 2.5 Inactive DFGin‑ABAminus in-none none-none TYR APEdihe_nnnai APEdist_aaan 71D Type1 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SWHB 2.5 Inactive DFGin‑ABAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 71D Type1 255 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
OTHER BUD32 KAE1B_METJA 8UNKB 2.91 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 356 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 9D85B 3.59 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
AGC PRKACA KAPCA_MOUSE 6MM6C 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM6E 2.39 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 19 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7A 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 17 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM7D 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6MM8C 1.85 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKND 2.75 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKOE 2.89 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKPE 2.85 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 17 - 351 0 SEP140,TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTTB 3.5 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNC 2.75 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNF 2.75 Inactive DFGin‑ABAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 8UKNH 2.75 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3TNPC 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3TNPF 2.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4WBBB 2.8 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6QC 2.52 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTSA 2.9 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4NTSB 2.9 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 9 - 351 0 TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5X3FB 3.38 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 317 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
CMGC DYRK1A DYR1A_MOUSE 9KRJA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus
CMGC GSK3B GSK3B_MOUSE 5AIRA 2.53 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 7PVUA 2.154 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVIA 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFY Type1 34 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
TYR TYK2-2 TYK2_MOUSE 4E20A 2.6 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MY Type1 885 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus
TYR TYK2-2 TYK2_MOUSE 4E1ZA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MX Type1 884 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 7Q52AAA 2.35 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE, 8ZC Allosteric, Type1 87 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii AXX Type1 74 - 746 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIB 2.4 Inactive DFGin‑ABAminus out-out in-none nonTYR APEdihe_aaiii APEdist_niii AXX Type1 74 - 745 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
CAMK None A0A3P9GXN4_ORYLA 9QJ2A 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 421 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK None A0A3P9GXN4_ORYLA 9QJ2B 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 419 - 763 0 None None Uncharacterized protein Oryzias latipes
OTHER PINK1 PINK1_PEDHC 6EQIC 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 147 - 574 0 SEP202,SEP204,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
AGC PKG KGP_PLAF7 8EM8A 2.54 Inactive DFGin‑ABAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii WLK Type1 28 - 817 0 None None cGMP-dependent protein kinase Plasmodium falciparum
CAMK CDPK2 CDPK2_PLAFK 4MVFA 2.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn STU Type1 60 - 511 0 None None Calcium-dependent protein kinase 2 Plasmodium falciparum
AGC PKG KGP_PLAVS 4RZ7A 2.351 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1E8 Type1 1 - 815 0 None None cGMP-dependent protein kinase Plasmodium vivax
AGC PKG KGP_PLAVS 5FETA 3.07 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 1TR Type1 2 - 816 0 None None cGMP-dependent protein kinase Plasmodium vivax
AGC PRKACA KAPCA_RAT 3TNQB 3.097 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 18 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4TA 3.4 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiio HTV, STU Allosteric, Type1 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFGA 3.46 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFRA 3.34 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, 32J Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 4QFSA 3.55 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, 32H Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4UA 3.27 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, HU7 Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
CAMK PRKAA1 AAPK1_RAT 6E4WA 3.35 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiio STU, HUG Type1, Allosteric 20 - 559 0 TPO183 None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Rattus norvegicus
TYR CSK CSK_RAT 1K9AB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 4 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CAMK RAD53 RAD53_YEAST 5XZWA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 15 - 465 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CMGC SSN3 SSN3_YEAST 7KPVA 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 48 - 489 0 None None Meiotic mRNA stability protein kinase SSN3 Saccharomyces cerevisiae
CMGC SSN3 SSN3_YEAST 7KPXA 4.4 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 48 - 489 0 None None Meiotic mRNA stability protein kinase SSN3 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2A 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2B 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSA 3.07 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ADP ATPlike 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSB 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ADP ATPlike 946 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
TYR VKR2 A0A3Q0KQ92_SCHMA 7ZVSC 3.07 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 943 - 1257 0 None None Guanylate cyclase Schistosoma mansoni
OTHER None A0ACD6BAW3_SERSF 5HNVA 1.41 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1QA 1.602 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ATP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1SA 1.45 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ACP ATPlike 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1TA 1.55 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo ADP ATPlike 11 - 298 0 None None PpkA N terminal Serratia sp.
OTHER None A0ACD6BAW3_SERSF 5X1RA 1.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiai APEdist_oioo No_ligand No_ligand 11 - 296 0 None None PpkA N terminal Serratia sp.
OTHER RNASEL A5H025_PIG 4O1PA 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PB 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PC 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PD 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OA 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OB 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OC 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OD 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER TCUR3610 D1ABX1_THECD 7WJ6A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 222 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 220 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 222 - 469 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 221 - 467 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
CAMK AURKBA AUKBA_XENLA 4C2WA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2WB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFXA 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 86 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFXB 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKB 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1 81 - 356 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5K3YA 1.6 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6Q4 Type1 88 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5K3YB 1.6 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6Q4 Type1 79 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFYA 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii H1N Type1 86 - 357 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2BFYB 1.8 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii H1N Type1 78 - 357 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGOA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD5 Type1 87 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGOB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD5 Type1 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGPA 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD6 Type1 88 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VGPB 1.7 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AD6 Type1 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 3ZTXA 1.95 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZTX Type1 87 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 3ZTXB 1.95 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ZTX Type1 78 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4B8MA 1.85 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 87 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4B8MB 1.85 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii VX6 Type1 78 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXB 1.86 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Back 77 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXA 1.86 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Front 87 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2VA 1.49 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJA Type1.5_Front 87 - 357 0 TPO248 None Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 4C2VB 1.49 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii YJA Type1.5_Front 76 - 356 0 TPO248 None Aurora kinase B-A Xenopus laevis