FGFR1 (Fibroblast growth factor receptor 1)

Group: TYR
Uniprot: FGFR1_HUMAN
Domain boundary: 478 - 756


Total number of chains: 140
Spatial Dihedral Chains Representative
DFGin BLAminus 9 AF-P11362-K1A
DFGin BLAplus 110 4UWCA
DFGin BLBminus 1 3KXXA
DFGin BLBplus 11 8JQIB
DFGin None 5 4NKAB
DFGout BBAminus 1 4V04B
DFGout None 3 4V04A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
3KXXB 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 764 C488A,R577E,C584S None 0
3KXXC 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 458 - 762 C488A,R577E,C584S None 0
3KXXD 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 458 - 762 C488A,R577E,C584S None 0
5FLFA 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 762 R675G None 0
5FLFB 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 764 R675G None 0
5FLFC 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 464 - 763 R675G None 0
5FLFD 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 465 - 763 R675G None 0
AF-P11362-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 470 - 764 None None 0
3GQIA 2.5 Active DFGin BLAminus in-in in-in ACP Type1 464 - 770 C488A,Y583F,C584S,Y585F X653,X654,X766 0
4RWIA 2.292 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 460 - 764 C488A,V561M,C584S None 0
4RWIB 2.292 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 461 - 763 C488A,V561M,C584S None 5
1FGKA 2.0 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 464 - 762 None None 0
1FGKB 2.0 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 461 - 761 C488A None 9
4UWYA 2.305 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 462 - 762 None None 0
4UWYB 2.305 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 459 - 762 None None 14
3KY2A 2.7 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 458 - 764 C488A,C584S None 0
3KY2B 2.7 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 460 - 763 C488A,C584S None 6
4RWLA 2.193 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 465 - 765 C488A,C584S None 3
5FLFE 2.58 Inactive DFGin BLAplus in-out none-out No_ligand No_ligand 466 - 761 R675G None 14
5AM7A 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 764 V561M None 0
5AM7B 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 762 V561M None 5
4RWKA 2.982 Inactive DFGin BLAplus in-in out-out 66T Type1 458 - 764 C488A,V561M,C584S None 0
4ZSAA 2.0 Inactive DFGin BLAplus in-in out-out 4UT Type1 464 - 765 C488A,C584S None 0
4ZSAB 2.0 Inactive DFGin BLAplus in-in none-out 4UT Type1 462 - 761 C488A,C584S None 6
5Z0SA 2.45 Inactive DFGin BLAplus in-in out-out 960 Type1 464 - 762 C488A,C584S None 0
5Z0SB 2.45 Inactive DFGin BLAplus in-in out-out 960 Type1 464 - 761 C488A,C584S None 1
6ITJA 1.994 Inactive DFGin BLAplus in-in out-out AXU Type1 464 - 765 C488A,C584S None 0
6ITJB 1.994 Inactive DFGin BLAplus in-in none-out AXU Type1 459 - 761 C488A,C584S None 5
9CD5A 2.939 Inactive DFGin BLAplus in-in none-out A1AV2 Type1 465 - 764 C488A,C584S None 6
9CD5B 2.939 Inactive DFGin BLAplus in-in out-out A1AV2 Type1 460 - 764 C488A,C584S None 2
4F63A 2.55 Inactive DFGin BLAplus in-in out-out 0S7 Type1 464 - 762 C488A,C584S None 0
4F63B 2.55 Inactive DFGin BLAplus in-none none-out 0S7 Type1 461 - 761 C488A,C584S None 9
4F64A 2.05 Inactive DFGin BLAplus in-in out-out 0S8 Type1 464 - 762 C488A,C584S None 0
4F64B 2.05 Inactive DFGin BLAplus in-in none-out 0S8 Type1 461 - 761 C488A,C584S None 9
4NKAA 2.19 Inactive DFGin BLAplus in-none none-out 2K7 Type1 464 - 765 C488A,C584S None 7
4NKSA 2.5 Inactive DFGin BLAplus in-in none-out 2M2 Type1 465 - 762 C488A,C584S None 6
4NKSB 2.5 Inactive DFGin BLAplus in-in none-out 2M2 Type1 461 - 761 C488A,C584S None 9
4UWBA 2.31 Inactive DFGin BLAplus in-in out-out JVT Type1 464 - 765 C488A,C584S None 1
4UWBB 2.31 Inactive DFGin BLAplus in-in out-out JVT Type1 459 - 765 C488A,C584S None 3
4UWCA 1.96 Inactive DFGin BLAplus in-in out-out 4Y0 Type1 465 - 765 C488A,C584S None 0
4UWCB 1.96 Inactive DFGin BLAplus in-in out-out 4Y0 Type1 459 - 764 C488A,C584S None 0
5O49A 1.91 Inactive DFGin BLAplus in-out out-out 9K5 Type1 464 - 764 C488A,C584S None 0
5O49B 1.91 Inactive DFGin BLAplus in-out none-out 9K5 Type1 460 - 765 C488A,C584S None 5
5O4AA 2.01 Inactive DFGin BLAplus in-out out-out 9K8 Type1 464 - 764 None None 0
5O4AB 2.01 Inactive DFGin BLAplus in-out none-out 9K8 Type1 460 - 763 None None 5
7OZBAAA 1.71 Inactive DFGin BLAplus in-in out-out 47I Type1 464 - 765 C488A,C584S None 0
7OZBBBB 1.71 Inactive DFGin BLAplus in-in out-out 47I Type1 460 - 764 C488A,C584S None 0
7OZDAAA 1.82 Inactive DFGin BLAplus in-in none-out 42I Type1 464 - 765 C488A,C584S None 6
7OZDBBB 1.82 Inactive DFGin BLAplus in-in none-out 42I Type1 460 - 763 C488A,C584S None 5
7OZFAAA 1.82 Inactive DFGin BLAplus in-in none-out 466 Type1 465 - 765 None None 5
7OZFBBB 1.82 Inactive DFGin BLAplus in-in none-out 466 Type1 460 - 763 None None 5
1AGWA 2.4 Inactive DFGin BLAplus in-out out-out SU2 Type1 464 - 762 None None 0
1AGWB 2.4 Inactive DFGin BLAplus in-in none-out SU2 Type1 461 - 761 C488A None 9
1FGIA 2.5 Inactive DFGin BLAplus in-out out-out SU1 Type1 464 - 762 C488A None 0
1FGIB 2.5 Inactive DFGin BLAplus in-in none-out SU1 Type1 461 - 761 C488A None 9
5AM6A 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 765 None None 0
5AM6B 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 762 None None 13
5UQ0A 2.3 Inactive DFGin BLAplus in-none none-out WP1 Type1 464 - 765 C488A,C584S None 17
5UQ0B 2.3 Inactive DFGin BLAplus in-in none-out WP1 Type1 463 - 762 C488A,C584S None 17
3JS2A 2.2 Inactive DFGin BLAplus in-in out-out VM1 Type1 464 - 765 C488A,C584S None 0
3JS2B 2.2 Inactive DFGin BLAplus in-in out-out VM1 Type1 459 - 762 C488A,C584S None 0
3GQLC 2.8 Inactive DFGin BLAplus in-in out-none GQL Type1 463 - 766 C488A None 16
8JMZA 1.988 Inactive DFGin BLAplus in-in out-out UKI Type1 460 - 765 C584S None 0
8JMZB 1.988 Inactive DFGin BLAplus in-in out-out UKI Type1 458 - 763 C584S None 3
5A46A 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1 464 - 766 None None 3
5A46B 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 766 None None 0
4RWKB 2.982 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 763 C488A,V561M,C584S None 7
3C4FA 2.07 Inactive DFGin BLAplus in-out out-out C4F Type1.5_Back 464 - 765 C488A None 0
3C4FB 2.07 Inactive DFGin BLAplus in-in out-out C4F Type1.5_Back 464 - 765 C488A None 0
3RHXA 2.01 Inactive DFGin BLAplus in-in out-out 3RH Type1.5_Back 464 - 764 C488A,C584S None 0
3RHXB 2.01 Inactive DFGin BLAplus in-in none-out 3RH Type1.5_Back 461 - 761 C488A,C584S None 6
5A4CA 2.09 Inactive DFGin BLAplus in-in none-out XOJ Type1.5_Back 464 - 765 C488A,C584S None 6
5A4CB 2.09 Inactive DFGin BLAplus in-in none-out XOJ Type1.5_Back 461 - 765 C488A,C584S None 5
4NK9B 2.57 Inactive DFGin BLAplus in-in none-out 2K5 Type1.5_Back 460 - 765 C488A,C584S None 8
4V05A 2.57 Inactive DFGin BLAplus in-in out-out 66T Type1.5_Back 464 - 765 None None 4
4V05B 2.57 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 764 None None 4
5EW8A 1.63 Inactive DFGin BLAplus in-in out-out 5SF Type1.5_Back 464 - 765 None None 0
5EW8B 1.63 Inactive DFGin BLAplus in-in out-out 5SF Type1.5_Back 461 - 765 None None 2
2FGIA 2.5 Inactive DFGin BLAplus in-in none-out PD1 Type1.5_Back 464 - 762 L457V,C488A,C584S None 2
2FGIB 2.5 Inactive DFGin BLAplus in-in none-out PD1 Type1.5_Back 461 - 761 L457V,C488A,C584S None 9
5B7VA 2.15 Inactive DFGin BLAplus in-in out-out LWJ Type1.5_Back 464 - 763 L457V,C488A,C584S None 3
4WUNA 1.65 Inactive DFGin BLAplus in-in none-none 66T Type1.5_Back 465 - 765 None None 18
4WUNB 1.65 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 461 - 762 None None 17
5UR1A 2.2 Inactive DFGin BLAplus in-in none-none YY9 Type1.5_Back 464 - 765 C488A,C584S None 18
6C18A 2.3 Inactive DFGin BLAplus in-in none-none YY5 Type1.5_Back 465 - 765 C488A,C584S None 18
6C19A 2.12 Inactive DFGin BLAplus in-in none-out YY7 Type1.5_Back 464 - 765 None None 17
6C19B 2.12 Inactive DFGin BLAplus in-in none-out YY7 Type1.5_Back 464 - 762 None None 17
6C1BA 2.0 Inactive DFGin BLAplus in-in none-none YY4 Type1.5_Back 465 - 765 C488A,C584S None 18
6C1BB 2.0 Inactive DFGin BLAplus in-in none-out YY4 Type1.5_Back 463 - 762 C488A,C584S None 17
6C1CA 2.15 Inactive DFGin BLAplus in-in none-none YY6 Type1.5_Back 465 - 765 C488A,C584S None 18
6C1CB 2.15 Inactive DFGin BLAplus in-in none-out YY6 Type1.5_Back 463 - 763 C488A,C584S None 16
6C1OA 2.29 Inactive DFGin BLAplus in-in none-out MK9 Type1.5_Back 464 - 765 C488A,C584S None 17
6C1OB 2.29 Inactive DFGin BLAplus in-in none-none MK9 Type1.5_Back 464 - 763 C488A,C584S None 18
6MZQA 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 464 - 765 None None 18
6MZQB 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 462 - 761 None None 19
4RWJA 2.489 Inactive DFGin BLAplus in-in out-out 66T Type1.5_Back 458 - 764 C488A,C584S None 1
4RWJB 2.489 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 763 C488A,C584S None 10
3GQLA 2.8 Inactive DFGin BLAplus in-in out-out GQL Type1.5_Back 463 - 774 C488A None 12
3TT0A 2.8 Inactive DFGin BLAplus in-in out-out 07J Type1.5_Back 461 - 765 C584S None 0
3TT0B 2.8 Inactive DFGin BLAplus in-in none-none 07J Type1.5_Back 459 - 763 C584S None 17
8Y22A 2.792 Inactive DFGin BLAplus in-in out-out A1LW9 Type1.5_Back 459 - 762 C584S None 4
8Y22B 2.792 Inactive DFGin BLAplus in-in out-out A1LW9 Type1.5_Back 463 - 765 C584S None 0
6NVLA 2.7 Inactive DFGin BLAplus in-in none-out XL6 Type1.5_Back 463 - 765 C584S None 9
6NVLB 2.7 Inactive DFGin BLAplus in-in none-none XL6 Type1.5_Back 461 - 761 C584S None 18
6NVLC 2.7 Inactive DFGin BLAplus in-in none-none XL6 Type1.5_Back 465 - 761 C584S None 9
6NVLD 2.7 Inactive DFGin BLAplus in-none none-out XL6 Type1.5_Back 471 - 762 C584S None 9
7WCLA 2.495 Inactive DFGin BLAplus in-in out-out 8ZF Type1.5_Back 459 - 764 C584S None 0
7WCLB 2.495 Inactive DFGin BLAplus in-in none-out 8ZF Type1.5_Back 458 - 763 C584S None 8
8XLOA 2.36 Inactive DFGin BLAplus in-in out-out A1LVQ Type1.5_Back 462 - 764 C584S None 0
8XLOB 2.36 Inactive DFGin BLAplus in-in none-out A1LVQ Type1.5_Back 458 - 763 C584S None 6
8XZ7B 1.75 Inactive DFGin BLAplus in-in out-out A1LWW Type1.5_Back 461 - 765 C584S None 0
6MZWA 2.2 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 464 - 765 None None 18
5VNDA 2.2 Inactive DFGin BLAplus in-in out-out 9ES Type1.5_Back 463 - 765 C488A,Y563C,C584S None 1
5VNDB 2.2 Inactive DFGin BLAplus in-in out-out 9ES Type1.5_Back 460 - 765 C488A,Y563C,C584S None 0
6P68A 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 462 - 763 C488A,Y563C None 3
6P68B 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 462 - 763 C488A,Y563C None 3
6P68C 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 463 - 763 C488A,Y563C None 3
6P69A 2.2 Inactive DFGin BLAplus in-in out-out O21 Type1.5_Back 462 - 765 C488A,Y563C None 0
6P69B 2.2 Inactive DFGin BLAplus in-in out-out O21 Type1.5_Back 461 - 762 C488A,Y563C None 0
3KXXA 3.2 Inactive DFGin BLBminus in-in in-in No_ligand No_ligand 461 - 765 C488A,R577E,C584S None 0
8JQIB 4.1 Inactive DFGin BLBplus in-in out-in No_ligand No_ligand 463 - 769 None None 0
8YKIA 2.79 Inactive DFGin BLBplus in-in none-out A1LY1 Type1 464 - 762 C488A None 16
8YKIB 2.79 Inactive DFGin BLBplus in-in none-out A1LY1 Type1 461 - 761 C488A None 17
3GQLB 2.8 Inactive DFGin BLBplus in-in out-none GQL Type1 463 - 765 C488A None 16
8XZ7A 1.75 Inactive DFGin BLBplus in-in none-out A1LWW Type1 458 - 765 C584S None 4
5ZV2A 2.86 Inactive DFGin BLBplus in-in out-out LEV Type1.5_Back 463 - 762 C488A None 2
5ZV2B 2.86 Inactive DFGin BLBplus in-in none-out LEV Type1.5_Back 461 - 764 C488A None 10
4NK9A 2.57 Inactive DFGin BLBplus in-in none-out 2K5 Type1.5_Back 464 - 765 C488A,C584S None 7
5B7VB 2.15 Inactive DFGin BLBplus in-in out-out LWJ Type1.5_Back 462 - 762 L457V,C488A,C584S None 6
5UR1B 2.2 Inactive DFGin BLBplus in-in none-none YY9 Type1.5_Back 464 - 763 C488A,C584S None 18
4RWLB 2.193 Inactive DFGin BLBplus in-in none-out 3ZC Type1.5_Back 458 - 764 C488A,C584S None 6
4F65A 2.26 Inactive DFGin None in-in none-out 0S9 Type1 464 - 765 C488A,C584S None 10
4NKAB 2.19 Inactive DFGin None in-in none-out 2K7 Type1 458 - 765 C488A,C584S None 6
4F65B 2.26 Inactive DFGin None in-in none-out 0S9 Type1.5_Back 460 - 763 C488A,C584S None 7
6C18B 2.3 Inactive DFGin None in-in none-none YY5 Type1.5_Back 466 - 762 C488A,C584S None 20
6MZWB 2.2 Inactive DFGin None in-in none-none TZ0 Type1.5_Back 463 - 762 None None 20
4V04B 2.12 Inactive DFGout BBAminus in-in none-out 0LI Type2 458 - 765 C488A,C584S None 6
4V01A 2.33 Inactive DFGout None in-in none-out 0LI Type2 465 - 765 C488A,C584S None 8
4V01B 2.33 Inactive DFGout None in-in none-out 0LI Type2 461 - 763 C488A,C584S None 8
4V04A 2.12 Inactive DFGout None in-in none-out 0LI Type2 463 - 765 C488A,C584S None 6

FGFR1 (Fibroblast growth factor receptor 1)

Group: TYR
Total number of chains: 140
Spatial Dihedral Chains Representative
DFGin BLAminus 9 AF-P11362-K1A
DFGin BLAplus 110 4UWCA
DFGin BLBminus 1 3KXXA
DFGin BLBplus 11 8JQIB
DFGin None 5 4NKAB
DFGout BBAminus 1 4V04B
DFGout None 3 4V04A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens FGFR1_HUMAN 3KXXB 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 764 C488A,R577E,C584S None 0
Homo sapiens FGFR1_HUMAN 3KXXC 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 458 - 762 C488A,R577E,C584S None 0
Homo sapiens FGFR1_HUMAN 3KXXD 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 458 - 762 C488A,R577E,C584S None 0
Homo sapiens FGFR1_HUMAN 5FLFA 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 762 R675G None 0
Homo sapiens FGFR1_HUMAN 5FLFB 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 460 - 764 R675G None 0
Homo sapiens FGFR1_HUMAN 5FLFC 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 464 - 763 R675G None 0
Homo sapiens FGFR1_HUMAN 5FLFD 2.58 Active DFGin BLAminus in-in in-in No_ligand No_ligand 465 - 763 R675G None 0
Homo sapiens FGFR1_HUMAN AF-P11362-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 470 - 764 None None 0
Homo sapiens FGFR1_HUMAN 3GQIA 2.5 Active DFGin BLAminus in-in in-in ACP Type1 464 - 770 C488A,Y583F,C584S,Y585F X653,X654,X766 0
Homo sapiens FGFR1_HUMAN 4RWIA 2.292 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 460 - 764 C488A,V561M,C584S None 0
Homo sapiens FGFR1_HUMAN 4RWIB 2.292 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 461 - 763 C488A,V561M,C584S None 5
Homo sapiens FGFR1_HUMAN 1FGKA 2.0 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 464 - 762 None None 0
Homo sapiens FGFR1_HUMAN 1FGKB 2.0 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 461 - 761 C488A None 9
Homo sapiens FGFR1_HUMAN 4UWYA 2.305 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 462 - 762 None None 0
Homo sapiens FGFR1_HUMAN 4UWYB 2.305 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 459 - 762 None None 14
Homo sapiens FGFR1_HUMAN 3KY2A 2.7 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 458 - 764 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 3KY2B 2.7 Inactive DFGin BLAplus in-in none-out No_ligand No_ligand 460 - 763 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 4RWLA 2.193 Inactive DFGin BLAplus in-in out-out No_ligand No_ligand 465 - 765 C488A,C584S None 3
Homo sapiens FGFR1_HUMAN 5FLFE 2.58 Inactive DFGin BLAplus in-out none-out No_ligand No_ligand 466 - 761 R675G None 14
Homo sapiens FGFR1_HUMAN 5AM7A 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 764 V561M None 0
Homo sapiens FGFR1_HUMAN 5AM7B 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 762 V561M None 5
Homo sapiens FGFR1_HUMAN 4RWKA 2.982 Inactive DFGin BLAplus in-in out-out 66T Type1 458 - 764 C488A,V561M,C584S None 0
Homo sapiens FGFR1_HUMAN 4ZSAA 2.0 Inactive DFGin BLAplus in-in out-out 4UT Type1 464 - 765 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 4ZSAB 2.0 Inactive DFGin BLAplus in-in none-out 4UT Type1 462 - 761 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 5Z0SA 2.45 Inactive DFGin BLAplus in-in out-out 960 Type1 464 - 762 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 5Z0SB 2.45 Inactive DFGin BLAplus in-in out-out 960 Type1 464 - 761 C488A,C584S None 1
Homo sapiens FGFR1_HUMAN 6ITJA 1.994 Inactive DFGin BLAplus in-in out-out AXU Type1 464 - 765 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 6ITJB 1.994 Inactive DFGin BLAplus in-in none-out AXU Type1 459 - 761 C488A,C584S None 5
Homo sapiens FGFR1_HUMAN 9CD5A 2.939 Inactive DFGin BLAplus in-in none-out A1AV2 Type1 465 - 764 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 9CD5B 2.939 Inactive DFGin BLAplus in-in out-out A1AV2 Type1 460 - 764 C488A,C584S None 2
Homo sapiens FGFR1_HUMAN 4F63A 2.55 Inactive DFGin BLAplus in-in out-out 0S7 Type1 464 - 762 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 4F63B 2.55 Inactive DFGin BLAplus in-none none-out 0S7 Type1 461 - 761 C488A,C584S None 9
Homo sapiens FGFR1_HUMAN 4F64A 2.05 Inactive DFGin BLAplus in-in out-out 0S8 Type1 464 - 762 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 4F64B 2.05 Inactive DFGin BLAplus in-in none-out 0S8 Type1 461 - 761 C488A,C584S None 9
Homo sapiens FGFR1_HUMAN 4NKAA 2.19 Inactive DFGin BLAplus in-none none-out 2K7 Type1 464 - 765 C488A,C584S None 7
Homo sapiens FGFR1_HUMAN 4NKSA 2.5 Inactive DFGin BLAplus in-in none-out 2M2 Type1 465 - 762 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 4NKSB 2.5 Inactive DFGin BLAplus in-in none-out 2M2 Type1 461 - 761 C488A,C584S None 9
Homo sapiens FGFR1_HUMAN 4UWBA 2.31 Inactive DFGin BLAplus in-in out-out JVT Type1 464 - 765 C488A,C584S None 1
Homo sapiens FGFR1_HUMAN 4UWBB 2.31 Inactive DFGin BLAplus in-in out-out JVT Type1 459 - 765 C488A,C584S None 3
Homo sapiens FGFR1_HUMAN 4UWCA 1.96 Inactive DFGin BLAplus in-in out-out 4Y0 Type1 465 - 765 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 4UWCB 1.96 Inactive DFGin BLAplus in-in out-out 4Y0 Type1 459 - 764 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 5O49A 1.91 Inactive DFGin BLAplus in-out out-out 9K5 Type1 464 - 764 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 5O49B 1.91 Inactive DFGin BLAplus in-out none-out 9K5 Type1 460 - 765 C488A,C584S None 5
Homo sapiens FGFR1_HUMAN 5O4AA 2.01 Inactive DFGin BLAplus in-out out-out 9K8 Type1 464 - 764 None None 0
Homo sapiens FGFR1_HUMAN 5O4AB 2.01 Inactive DFGin BLAplus in-out none-out 9K8 Type1 460 - 763 None None 5
Homo sapiens FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin BLAplus in-in out-out 47I Type1 464 - 765 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin BLAplus in-in out-out 47I Type1 460 - 764 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 7OZDAAA 1.82 Inactive DFGin BLAplus in-in none-out 42I Type1 464 - 765 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 7OZDBBB 1.82 Inactive DFGin BLAplus in-in none-out 42I Type1 460 - 763 C488A,C584S None 5
Homo sapiens FGFR1_HUMAN 7OZFAAA 1.82 Inactive DFGin BLAplus in-in none-out 466 Type1 465 - 765 None None 5
Homo sapiens FGFR1_HUMAN 7OZFBBB 1.82 Inactive DFGin BLAplus in-in none-out 466 Type1 460 - 763 None None 5
Homo sapiens FGFR1_HUMAN 1AGWA 2.4 Inactive DFGin BLAplus in-out out-out SU2 Type1 464 - 762 None None 0
Homo sapiens FGFR1_HUMAN 1AGWB 2.4 Inactive DFGin BLAplus in-in none-out SU2 Type1 461 - 761 C488A None 9
Homo sapiens FGFR1_HUMAN 1FGIA 2.5 Inactive DFGin BLAplus in-out out-out SU1 Type1 464 - 762 C488A None 0
Homo sapiens FGFR1_HUMAN 1FGIB 2.5 Inactive DFGin BLAplus in-in none-out SU1 Type1 461 - 761 C488A None 9
Homo sapiens FGFR1_HUMAN 5AM6A 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 765 None None 0
Homo sapiens FGFR1_HUMAN 5AM6B 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 762 None None 13
Homo sapiens FGFR1_HUMAN 5UQ0A 2.3 Inactive DFGin BLAplus in-none none-out WP1 Type1 464 - 765 C488A,C584S None 17
Homo sapiens FGFR1_HUMAN 5UQ0B 2.3 Inactive DFGin BLAplus in-in none-out WP1 Type1 463 - 762 C488A,C584S None 17
Homo sapiens FGFR1_HUMAN 3JS2A 2.2 Inactive DFGin BLAplus in-in out-out VM1 Type1 464 - 765 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 3JS2B 2.2 Inactive DFGin BLAplus in-in out-out VM1 Type1 459 - 762 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 3GQLC 2.8 Inactive DFGin BLAplus in-in out-none GQL Type1 463 - 766 C488A None 16
Homo sapiens FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin BLAplus in-in out-out UKI Type1 460 - 765 C584S None 0
Homo sapiens FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin BLAplus in-in out-out UKI Type1 458 - 763 C584S None 3
Homo sapiens FGFR1_HUMAN 5A46A 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1 464 - 766 None None 3
Homo sapiens FGFR1_HUMAN 5A46B 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1 458 - 766 None None 0
Homo sapiens FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 763 C488A,V561M,C584S None 7
Homo sapiens FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin BLAplus in-out out-out C4F Type1.5_Back 464 - 765 C488A None 0
Homo sapiens FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin BLAplus in-in out-out C4F Type1.5_Back 464 - 765 C488A None 0
Homo sapiens FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin BLAplus in-in out-out 3RH Type1.5_Back 464 - 764 C488A,C584S None 0
Homo sapiens FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin BLAplus in-in none-out 3RH Type1.5_Back 461 - 761 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin BLAplus in-in none-out XOJ Type1.5_Back 464 - 765 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin BLAplus in-in none-out XOJ Type1.5_Back 461 - 765 C488A,C584S None 5
Homo sapiens FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin BLAplus in-in none-out 2K5 Type1.5_Back 460 - 765 C488A,C584S None 8
Homo sapiens FGFR1_HUMAN 4V05A 2.57 Inactive DFGin BLAplus in-in out-out 66T Type1.5_Back 464 - 765 None None 4
Homo sapiens FGFR1_HUMAN 4V05B 2.57 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 764 None None 4
Homo sapiens FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin BLAplus in-in out-out 5SF Type1.5_Back 464 - 765 None None 0
Homo sapiens FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin BLAplus in-in out-out 5SF Type1.5_Back 461 - 765 None None 2
Homo sapiens FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin BLAplus in-in none-out PD1 Type1.5_Back 464 - 762 L457V,C488A,C584S None 2
Homo sapiens FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin BLAplus in-in none-out PD1 Type1.5_Back 461 - 761 L457V,C488A,C584S None 9
Homo sapiens FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin BLAplus in-in out-out LWJ Type1.5_Back 464 - 763 L457V,C488A,C584S None 3
Homo sapiens FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin BLAplus in-in none-none 66T Type1.5_Back 465 - 765 None None 18
Homo sapiens FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 461 - 762 None None 17
Homo sapiens FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin BLAplus in-in none-none YY9 Type1.5_Back 464 - 765 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 6C18A 2.3 Inactive DFGin BLAplus in-in none-none YY5 Type1.5_Back 465 - 765 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 6C19A 2.12 Inactive DFGin BLAplus in-in none-out YY7 Type1.5_Back 464 - 765 None None 17
Homo sapiens FGFR1_HUMAN 6C19B 2.12 Inactive DFGin BLAplus in-in none-out YY7 Type1.5_Back 464 - 762 None None 17
Homo sapiens FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin BLAplus in-in none-none YY4 Type1.5_Back 465 - 765 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin BLAplus in-in none-out YY4 Type1.5_Back 463 - 762 C488A,C584S None 17
Homo sapiens FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin BLAplus in-in none-none YY6 Type1.5_Back 465 - 765 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin BLAplus in-in none-out YY6 Type1.5_Back 463 - 763 C488A,C584S None 16
Homo sapiens FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin BLAplus in-in none-out MK9 Type1.5_Back 464 - 765 C488A,C584S None 17
Homo sapiens FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin BLAplus in-in none-none MK9 Type1.5_Back 464 - 763 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 464 - 765 None None 18
Homo sapiens FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 462 - 761 None None 19
Homo sapiens FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin BLAplus in-in out-out 66T Type1.5_Back 458 - 764 C488A,C584S None 1
Homo sapiens FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin BLAplus in-in none-out 66T Type1.5_Back 459 - 763 C488A,C584S None 10
Homo sapiens FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin BLAplus in-in out-out GQL Type1.5_Back 463 - 774 C488A None 12
Homo sapiens FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin BLAplus in-in out-out 07J Type1.5_Back 461 - 765 C584S None 0
Homo sapiens FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin BLAplus in-in none-none 07J Type1.5_Back 459 - 763 C584S None 17
Homo sapiens FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin BLAplus in-in out-out A1LW9 Type1.5_Back 459 - 762 C584S None 4
Homo sapiens FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin BLAplus in-in out-out A1LW9 Type1.5_Back 463 - 765 C584S None 0
Homo sapiens FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin BLAplus in-in none-out XL6 Type1.5_Back 463 - 765 C584S None 9
Homo sapiens FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin BLAplus in-in none-none XL6 Type1.5_Back 461 - 761 C584S None 18
Homo sapiens FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin BLAplus in-in none-none XL6 Type1.5_Back 465 - 761 C584S None 9
Homo sapiens FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin BLAplus in-none none-out XL6 Type1.5_Back 471 - 762 C584S None 9
Homo sapiens FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin BLAplus in-in out-out 8ZF Type1.5_Back 459 - 764 C584S None 0
Homo sapiens FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin BLAplus in-in none-out 8ZF Type1.5_Back 458 - 763 C584S None 8
Homo sapiens FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin BLAplus in-in out-out A1LVQ Type1.5_Back 462 - 764 C584S None 0
Homo sapiens FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin BLAplus in-in none-out A1LVQ Type1.5_Back 458 - 763 C584S None 6
Homo sapiens FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin BLAplus in-in out-out A1LWW Type1.5_Back 461 - 765 C584S None 0
Homo sapiens FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back 464 - 765 None None 18
Homo sapiens FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin BLAplus in-in out-out 9ES Type1.5_Back 463 - 765 C488A,Y563C,C584S None 1
Homo sapiens FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin BLAplus in-in out-out 9ES Type1.5_Back 460 - 765 C488A,Y563C,C584S None 0
Homo sapiens FGFR1_HUMAN 6P68A 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 462 - 763 C488A,Y563C None 3
Homo sapiens FGFR1_HUMAN 6P68B 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 462 - 763 C488A,Y563C None 3
Homo sapiens FGFR1_HUMAN 6P68C 2.9 Inactive DFGin BLAplus in-in out-out O1Y Type1.5_Back 463 - 763 C488A,Y563C None 3
Homo sapiens FGFR1_HUMAN 6P69A 2.2 Inactive DFGin BLAplus in-in out-out O21 Type1.5_Back 462 - 765 C488A,Y563C None 0
Homo sapiens FGFR1_HUMAN 6P69B 2.2 Inactive DFGin BLAplus in-in out-out O21 Type1.5_Back 461 - 762 C488A,Y563C None 0
Homo sapiens FGFR1_HUMAN 3KXXA 3.2 Inactive DFGin BLBminus in-in in-in No_ligand No_ligand 461 - 765 C488A,R577E,C584S None 0
Homo sapiens FGFR1_HUMAN 8JQIB 4.1 Inactive DFGin BLBplus in-in out-in No_ligand No_ligand 463 - 769 None None 0
Homo sapiens FGFR1_HUMAN 8YKIA 2.79 Inactive DFGin BLBplus in-in none-out A1LY1 Type1 464 - 762 C488A None 16
Homo sapiens FGFR1_HUMAN 8YKIB 2.79 Inactive DFGin BLBplus in-in none-out A1LY1 Type1 461 - 761 C488A None 17
Homo sapiens FGFR1_HUMAN 3GQLB 2.8 Inactive DFGin BLBplus in-in out-none GQL Type1 463 - 765 C488A None 16
Homo sapiens FGFR1_HUMAN 8XZ7A 1.75 Inactive DFGin BLBplus in-in none-out A1LWW Type1 458 - 765 C584S None 4
Homo sapiens FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin BLBplus in-in out-out LEV Type1.5_Back 463 - 762 C488A None 2
Homo sapiens FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin BLBplus in-in none-out LEV Type1.5_Back 461 - 764 C488A None 10
Homo sapiens FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin BLBplus in-in none-out 2K5 Type1.5_Back 464 - 765 C488A,C584S None 7
Homo sapiens FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin BLBplus in-in out-out LWJ Type1.5_Back 462 - 762 L457V,C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin BLBplus in-in none-none YY9 Type1.5_Back 464 - 763 C488A,C584S None 18
Homo sapiens FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin BLBplus in-in none-out 3ZC Type1.5_Back 458 - 764 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 4F65A 2.26 Inactive DFGin None in-in none-out 0S9 Type1 464 - 765 C488A,C584S None 10
Homo sapiens FGFR1_HUMAN 4NKAB 2.19 Inactive DFGin None in-in none-out 2K7 Type1 458 - 765 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 4F65B 2.26 Inactive DFGin None in-in none-out 0S9 Type1.5_Back 460 - 763 C488A,C584S None 7
Homo sapiens FGFR1_HUMAN 6C18B 2.3 Inactive DFGin None in-in none-none YY5 Type1.5_Back 466 - 762 C488A,C584S None 20
Homo sapiens FGFR1_HUMAN 6MZWB 2.2 Inactive DFGin None in-in none-none TZ0 Type1.5_Back 463 - 762 None None 20
Homo sapiens FGFR1_HUMAN 4V04B 2.12 Inactive DFGout BBAminus in-in none-out 0LI Type2 458 - 765 C488A,C584S None 6
Homo sapiens FGFR1_HUMAN 4V01A 2.33 Inactive DFGout None in-in none-out 0LI Type2 465 - 765 C488A,C584S None 8
Homo sapiens FGFR1_HUMAN 4V01B 2.33 Inactive DFGout None in-in none-out 0LI Type2 461 - 763 C488A,C584S None 8
Homo sapiens FGFR1_HUMAN 4V04A 2.12 Inactive DFGout None in-in none-out 0LI Type2 463 - 765 C488A,C584S None 6

FGFR1 (Fibroblast growth factor receptor 1)

No non-human structures known.