TYR_EGFR (Epidermal growth factor receptor)

Total number of chains: 513
Uniprot: EGFR_HUMAN
Kinase Domain Residues: 712 - 970
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 197 AF-P00533-K1A
DFGin BLAplus 11 8A2AA
DFGin ABAminus 5 3IKAA
DFGin BLBminus 4 8A2DA
DFGin BLBplus 166 6V66D
DFGin BLBtrans 92 6V66A
DFGin None 13 4RIYD
DFGinter None 8 2JIUB
DFGout BBAminus 12 5HG8A
DFGout None 5 4I1ZA

Database table as tsv

PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
3IKAA 2.9 Inactive DFGin‑ABAminus in-in in-in 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor
7ER2A 2.662 Inactive DFGin‑ABAminus in-in in-in JAU Type1 697 - 1018 7 None T790M,C797S Epidermal growth factor receptor
8KFQA 3.22 Inactive DFGin‑ABAminus in-in in-none VUZ Type1 697 - 1018 14 None T790M,L858R Epidermal growth factor receptor
4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none YUN Type1 697 - 1017 13 None T790M,L858R Epidermal growth factor receptor
4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none YUN Type1 698 - 1017 14 None T790M,L858R Epidermal growth factor receptor
8HV4A 2.2 Active DFGin‑BLAminus in-in in-in PE5, MWU Allosteric, Type1 696 - 1020 3 None E865A,E866A,K867A Epidermal growth factor receptor
8HV6A 2.2 Active DFGin‑BLAminus in-in in-in PE5, N86 Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
8HV7A 2.69 Active DFGin‑BLAminus in-in in-in PE5, N8O Allosteric, Type1 696 - 1019 6 None E865A,E866A,K867A Epidermal growth factor receptor
8HV8A 2.4 Active DFGin‑BLAminus in-in in-in PE5, N99 Allosteric, Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
8HV9A 2.5 Active DFGin‑BLAminus in-in in-in PE5, N9L Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
9BY6A 2.551 Active DFGin‑BLAminus in-in in-in PDO, Q6K Allosteric, Type1 698 - 1009 0 None None Epidermal growth factor receptor
8HV1A 2.4 Active DFGin‑BLAminus in-in in-in PE5, N6N Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
8HV3A 2.4 Active DFGin‑BLAminus in-in in-in PE5, MWU Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
8HV5A 2.2 Active DFGin‑BLAminus in-in in-in PE5, N7C Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
9BY4A 2.307 Active DFGin‑BLAminus in-in in-in PDO, Q6K, PDO, PDO Allosteric, Type1, Allosteric, Type1 696 - 1010 0 None None Epidermal growth factor receptor
2JITA 3.1 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1016 0 None T790M Epidermal growth factor receptor
3UG1A 2.75 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
AF-P00533-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor
AF-P00533-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor
2J5EA 3.1 Inactive DFGin‑BLAminus in-in in-out No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor
2GS2A 2.8 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1018 0 None None Epidermal growth factor receptor
2GS6A 2.6 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1019 0 None None Epidermal growth factor receptor
4WRGA 1.9 Inactive DFGin‑BLAminus in-out in-none No_ligand No_ligand 696 - 1019 2 None None Epidermal growth factor receptor
7SI1A 1.6 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 695 - 1020 0 None None Epidermal growth factor receptor
4TKSA 3.202 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 697 - 1019 0 None None Epidermal growth factor receptor
1M14A 2.6 Inactive DFGin‑BLAminus in-out in-out No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor
2EB2A 2.5 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1019 1 None None Epidermal growth factor receptor
4R3PA 2.905 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
4R3RA 3.25 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
5CZHA 2.8 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
5CZIA 2.6 Inactive DFGin‑BLAminus out-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
9U8CE 3.5 Inactive DFGin‑BLAminus in-none in-out No_ligand No_ligand 696 - 982 0 None None Epidermal growth factor receptor
8H7XA 3.404 Active DFGin‑BLAminus in-in in-in 6GY Type1 697 - 1019 0 None T790M,C797S Epidermal growth factor receptor
5XGNA 3.0 Inactive DFGin‑BLAminus in-in in-out 85X Type1 697 - 1020 0 None T790M,C797S Epidermal growth factor receptor
6JRXA 2.201 Active DFGin‑BLAminus in-in in-in 9JO Type1 696 - 1017 3 None T790M,C797S Epidermal growth factor receptor
5J9YA 2.8 Active DFGin‑BLAminus in-in in-in 6HL Type1 697 - 1019 3 None None Epidermal growth factor receptor
8EMEB 3.32 Inactive DFGin‑BLAminus out-out none-none ZNL Type1 702 - 1007 19 None T790M,V948R Epidermal growth factor receptor
5J9ZA 2.5 None DFGin‑BLAminus in-in in-none 6HJ Type1 696 - 1020 15 None T790M Epidermal growth factor receptor
7A6IA 2.4 Inactive DFGin‑BLAminus out-out in-out R1W Type1 703 - 984 0 None T790M,V948R Epidermal growth factor receptor
5X2KA 3.201 Active DFGin‑BLAminus in-in in-in 0UN Type1 696 - 1020 6 None T790M Epidermal growth factor receptor
2JIUA 3.05 Inactive DFGin‑BLAminus in-out in-in AEE Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
5FEQA 3.4 Inactive DFGin‑BLAminus in-in in-out 5XH Type1 697 - 1017 5 None T790M Epidermal growth factor receptor
4G5PA 3.17 Active DFGin‑BLAminus in-in in-in 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
5GMPA 2.797 Inactive DFGin‑BLAminus in-in in-out F62 Type1 696 - 1019 11 None T790M Epidermal growth factor receptor
5GTZA 2.999 Inactive DFGin‑BLAminus in-in in-out 81C Type1 697 - 1020 7 None T790M Epidermal growth factor receptor
5XDKA 2.346 Active DFGin‑BLAminus in-in in-in 8JC Type1 696 - 1018 0 None T790M Epidermal growth factor receptor
6JX4A 2.531 None DFGin‑BLAminus in-in in-none YY3 Type1 696 - 1018 8 None T790M Epidermal growth factor receptor
4WD5A 3.3 Inactive DFGin‑BLAminus out-out in-out 3LH Type1 694 - 1021 0 None T790M Epidermal growth factor receptor
5Y9TA 3.25 Active DFGin‑BLAminus in-in in-in 8RC Type1 697 - 1020 0 None T790M Epidermal growth factor receptor
3UG2A 2.5 Inactive DFGin‑BLAminus in-out in-in IRE Type1 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
3VJNA 2.34 Inactive DFGin‑BLAminus in-out in-in ANP Type1 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
7VRAA 2.41 None DFGin‑BLAminus in-in in-none I0A Type1 696 - 1018 11 None T790M,C797S Epidermal growth factor receptor
7VREA 2.507 None DFGin‑BLAminus in-in in-none 7VH Type1 696 - 1018 8 None T790M,C797S Epidermal growth factor receptor
6S89A 2.701 Active DFGin‑BLAminus in-in in-in L0Q Type1 697 - 1017 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
6S8AA 2.6 Active DFGin‑BLAminus in-in in-in L0N Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
7ZYMA 2.5 Active DFGin‑BLAminus in-in in-in 6GY Type1 696 - 1020 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
7ZYNA 2.3 Active DFGin‑BLAminus in-in in-in 0UN Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
7ZYPA 2.8 None DFGin‑BLAminus in-none in-in R25 Type1 695 - 1019 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
9JQ1A 3.02 Active DFGin‑BLAminus in-in in-in A1ECU Type1 697 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor
7OXBA 2.56 Active DFGin‑BLAminus in-in in-in 35Z Type1 696 - 1019 6 None None Epidermal growth factor receptor
9KLWA 2.67 None DFGin‑BLAminus in-in in-none A1L53 Type1 696 - 1019 13 None T790M,L858R Epidermal growth factor receptor
8DSWA 2.39 None DFGin‑BLAminus none-none in-none ANP Type1 696 - 1017 9 None None Epidermal growth factor receptor
8WD4A 2.55 Active DFGin‑BLAminus in-in in-in W7W Type1 696 - 1019 11 None T790M,C797S,L858R Epidermal growth factor receptor
6LUBA 2.315 Active DFGin‑BLAminus in-in in-in EUX Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor
6LUDA 2.05 Active DFGin‑BLAminus in-in in-in YY3 Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor
9D3VA 2.32 Inactive DFGin‑BLAminus in-in in-out A1A5V Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
9D3WA 2.53 Active DFGin‑BLAminus in-in in-in A1A5L Type1 696 - 1017 11 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
8HVAA 2.77 Active DFGin‑BLAminus in-in in-in N9R Type1 696 - 1020 4 None E865A,E866A,K867A Epidermal growth factor receptor
6JZ0A 2.86 Active DFGin‑BLAminus in-in in-in CKO Type1 696 - 1019 0 None None Epidermal growth factor receptor
2ITWA 2.88 Inactive DFGin‑BLAminus in-out in-in ITQ Type1 696 - 1018 0 None None Epidermal growth factor receptor
2ITXA 2.98 Active DFGin‑BLAminus in-in in-in ANP Type1 697 - 1019 4 None None Epidermal growth factor receptor
2ITYA 3.42 None DFGin‑BLAminus in-in in-none IRE Type1 697 - 1019 10 None None Epidermal growth factor receptor
2J5FA 3.0 None DFGin‑BLAminus in-in in-none DJK Type1 696 - 1020 8 None None Epidermal growth factor receptor
2J6MA 3.1 Active DFGin‑BLAminus in-in in-in AEE Type1 697 - 1020 0 None None Epidermal growth factor receptor
6VH4A 2.8 Active DFGin‑BLAminus in-in in-in QQM Type1 696 - 1019 3 None None Epidermal growth factor receptor
6VHNA 2.4 None DFGin‑BLAminus in-in in-none QQJ Type1 696 - 1019 13 None None Epidermal growth factor receptor
6VHPA 3.6 None DFGin‑BLAminus in-in in-none QP1 Type1 696 - 1019 5 None None Epidermal growth factor receptor
8G63A 2.5 None DFGin‑BLAminus in-in in-none YXT Type1 696 - 1017 14 None None Epidermal growth factor receptor
9MSRA 1.93 None DFGin‑BLAminus in-in in-none A1BRC Type1 697 - 1017 13 None None Epidermal growth factor receptor
9MSSA 2.09 Active DFGin‑BLAminus in-in in-in A1BYO Type1 697 - 1017 6 None None Epidermal growth factor receptor
9MSTA 2.57 Active DFGin‑BLAminus in-in in-in A1BYN Type1 696 - 1017 5 None None Epidermal growth factor receptor
9NHWA 2.73 None DFGin‑BLAminus in-in in-none A1BYD Type1 698 - 1017 8 None None Epidermal growth factor receptor
9NISA 2.23 None DFGin‑BLAminus in-in in-none A1BYK Type1 696 - 1016 10 None None Epidermal growth factor receptor
9NJ7A 2.53 None DFGin‑BLAminus in-in in-none A1BYL Type1 698 - 1017 15 None None Epidermal growth factor receptor
9NJNA 2.24 None DFGin‑BLAminus in-in in-none A1BYS Type1 698 - 1017 13 None None Epidermal growth factor receptor
9NM0A 2.59 None DFGin‑BLAminus in-in in-none VO7 Type1 697 - 1018 16 None None Epidermal growth factor receptor
9OS6A 2.75 None DFGin‑BLAminus in-in in-none A1CEA Type1 697 - 1017 14 None None Epidermal growth factor receptor
9OU9A 2.1 None DFGin‑BLAminus in-in in-none A1CEL Type1 697 - 1017 14 None None Epidermal growth factor receptor
9PMZA 2.33 None DFGin‑BLAminus in-in in-none A1CI6 Type1 696 - 1017 14 None None Epidermal growth factor receptor
9Q0SA 2.46 None DFGin‑BLAminus in-in in-none A1CNG Type1 696 - 1017 8 None None Epidermal growth factor receptor
9H46A 3.163 Inactive DFGin‑BLAminus in-in in-out A1ISA Type1 696 - 1019 11 None None Epidermal growth factor receptor
7UKVA 2.4 None DFGin‑BLAminus in-in in-none ZRT Type1 696 - 1018 6 None None Epidermal growth factor receptor
5FEDA 2.651 Active DFGin‑BLAminus in-in in-in 5X4 Type1 697 - 1017 4 None None Epidermal growth factor receptor
7T4IA 2.61 Active DFGin‑BLAminus in-in in-in R28 Type1 697 - 1017 0 None None Epidermal growth factor receptor
4JQ7A 2.73 Inactive DFGin‑BLAminus in-in in-out KJQ Type1 696 - 1019 0 None None Epidermal growth factor receptor
4JQ8A 2.83 Inactive DFGin‑BLAminus in-in in-out KJ8 Type1 696 - 1019 0 None None Epidermal growth factor receptor
4JR3A 2.7 Inactive DFGin‑BLAminus in-in in-out KJR Type1 696 - 1019 0 None None Epidermal growth factor receptor
4JRVA 2.8 Inactive DFGin‑BLAminus in-in in-out KJV Type1 696 - 1019 0 None None Epidermal growth factor receptor
4LI5A 2.64 Active DFGin‑BLAminus in-in in-in 1WY Type1 696 - 1020 0 None None Epidermal growth factor receptor
4I23A 2.8 Active DFGin‑BLAminus in-in in-in 1C9 Type1 695 - 1018 0 None None Epidermal growth factor receptor
5UGBA 2.53 Active DFGin‑BLAminus in-in in-in 8BM Type1 695 - 1018 0 None None Epidermal growth factor receptor
7AEIA 2.65 Active DFGin‑BLAminus in-in in-in R85 Type1 697 - 1018 0 None None Epidermal growth factor receptor
8PNZA 2.51 Inactive DFGin‑BLAminus in-out in-in 2I0 Type1 695 - 1018 0 None None Epidermal growth factor receptor
9FZRA 1.991 Active DFGin‑BLAminus in-in in-in A1IHC Type1 696 - 1019 0 None None Epidermal growth factor receptor
9FZSA 2.121 Active DFGin‑BLAminus in-in in-in A1IHD Type1 696 - 1019 0 None None Epidermal growth factor receptor
5JEBA 3.298 Inactive DFGin‑BLAminus in-in in-out 6JS Type1 699 - 999 0 None V948R Epidermal growth factor receptor
4WKQA 1.85 Active DFGin‑BLAminus in-in in-in IRE Type1 696 - 1020 0 None None Epidermal growth factor receptor
4ZAUA 2.8 None DFGin‑BLAminus in-in in-none YY3 Type1 698 - 1017 5 None None Epidermal growth factor receptor
8SC7A 1.984 Active DFGin‑BLAminus in-in in-in D0D Type1 696 - 1019 0 None None Epidermal growth factor receptor
9KL4A 2.32 Active DFGin‑BLAminus in-in in-in A1L53 Type1 696 - 1019 0 None None Epidermal growth factor receptor
5CAVA 2.73 Active DFGin‑BLAminus in-in in-in 4ZQ Type1 697 - 1020 0 None None Epidermal growth factor receptor
5EM8A 2.8 Active DFGin‑BLAminus in-in in-in 5Q4 Type1 696 - 1018 2 None None Epidermal growth factor receptor
7KXZA 2.4 Active DFGin‑BLAminus in-in in-in XA4 Type1 696 - 1017 0 None None Epidermal growth factor receptor
7U99A 2.5 Active DFGin‑BLAminus in-in in-in M0R Type1 695 - 1018 0 None None Epidermal growth factor receptor
7U9AA 2.6 None DFGin‑BLAminus in-in in-none M19 Type1 695 - 1018 4 None None Epidermal growth factor receptor
8F1HA 2.8 Active DFGin‑BLAminus in-in in-in X9H Type1 697 - 1018 0 None None Epidermal growth factor receptor
8F1XA 2.3 Active DFGin‑BLAminus in-in in-in R28 Type1 696 - 1018 0 None None Epidermal growth factor receptor
8F1YA 2.75 Active DFGin‑BLAminus in-in in-in R2E Type1 696 - 1019 3 None None Epidermal growth factor receptor
8TJLA 2.7 Active DFGin‑BLAminus in-in in-in HZ6 Type1 696 - 1019 2 None None Epidermal growth factor receptor
8HV2A 2.8 Active DFGin‑BLAminus in-in in-in MWU Type1 697 - 1019 5 None None Epidermal growth factor receptor
1M17A 2.6 Inactive DFGin‑BLAminus in-in in-out AQ4 Type1 696 - 1019 0 None None Epidermal growth factor receptor
7B85A 2.5 None DFGin‑BLAminus in-in in-none R28 Type1 697 - 1020 2 None None Epidermal growth factor receptor
3VJOA 2.64 Inactive DFGin‑BLAminus in-out in-in ANP Type1 696 - 1018 0 None None Epidermal growth factor receptor
7AEMA 2.65 Active DFGin‑BLAminus in-in in-in 6GY Type1 695 - 1018 0 None None Epidermal growth factor receptor
2ITNA 2.47 None DFGin‑BLAminus in-in in-none ANP Type1 696 - 1019 9 None G719S Epidermal growth factor receptor
2ITOA 3.25 None DFGin‑BLAminus in-in in-none IRE Type1 696 - 1019 9 None G719S Epidermal growth factor receptor
2ITPA 2.74 Active DFGin‑BLAminus in-in in-in AEE Type1 697 - 1018 0 None G719S Epidermal growth factor receptor
2ITQA 2.68 Active DFGin‑BLAminus in-in in-in ITQ Type1 697 - 1018 0 None G719S Epidermal growth factor receptor
6S9BA 3.25 None DFGin‑BLAminus in-in in-none L1H Type1 697 - 1019 12 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
6S9CA 2.73 None DFGin‑BLAminus in-in in-none L1K Type1 696 - 1019 12 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
6S9DA 2.67 Active DFGin‑BLAminus in-in in-in L3Z Type1 696 - 1017 11 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
8HY7A 2.91 Inactive DFGin‑BLAminus in-out in-none NSO Type1 696 - 1019 14 None E865A,E866A,K867A Epidermal growth factor receptor
4RJ4A 2.78 None DFGin‑BLAminus in-in in-none 3QW Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
4RJ7A 2.55 None DFGin‑BLAminus in-in in-none 3R1 Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
4RJ8A 2.5 None DFGin‑BLAminus in-in in-none 3QS Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5C8KA 3.0 None DFGin‑BLAminus in-in in-none 4YV Type1 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5C8MA 2.9 None DFGin‑BLAminus in-in in-none 4YW Type1 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5C8NA 2.401 None DFGin‑BLAminus in-in in-none 4YX Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CALA 2.7 None DFGin‑BLAminus in-in in-none 4Z8 Type1 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CANA 2.8 None DFGin‑BLAminus in-in in-none 4ZB Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CAOA 2.6 None DFGin‑BLAminus in-in none-none 4ZG Type1 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CAPA 2.4 None DFGin‑BLAminus in-in in-none 4ZH Type1 697 - 1019 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5EM7A 2.81 None DFGin‑BLAminus in-in in-none 5Q4 Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5HCXA 2.6 None DFGin‑BLAminus in-in in-none 60B Type1 696 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5HCZA 2.62 None DFGin‑BLAminus in-in in-none 60E Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5HIBA 2.85 Active DFGin‑BLAminus in-in in-in 63M Type1 696 - 1018 5 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
6JRKA 2.796 Inactive DFGin‑BLAminus in-out in-none C6O Type1 696 - 1018 15 None E865A,E866A,K867A Epidermal growth factor receptor
2ITTA 2.73 None DFGin‑BLAminus in-in in-none AEE Type1 697 - 1019 9 None L858R Epidermal growth factor receptor
2ITUA 2.8 Inactive DFGin‑BLAminus in-out in-none ITQ Type1 696 - 1019 10 None L858R Epidermal growth factor receptor
2ITVA 2.47 None DFGin‑BLAminus in-in in-none ANP Type1 696 - 1019 9 None L858R Epidermal growth factor receptor
2ITZA 2.8 Inactive DFGin‑BLAminus in-out in-none IRE Type1 697 - 1020 10 None L858R Epidermal growth factor receptor
5X26A 2.951 None DFGin‑BLAminus in-in in-none 7XO Type1 697 - 1020 9 None L858R Epidermal growth factor receptor
5X27A 2.952 None DFGin‑BLAminus in-in in-none 7XR Type1 697 - 1020 9 None L858R Epidermal growth factor receptor
5X28A 2.952 None DFGin‑BLAminus in-in in-none 7XU Type1 697 - 1020 9 None L858R Epidermal growth factor receptor
5XDLA 2.7 None DFGin‑BLAminus in-in in-none 8JC Type1 696 - 1018 15 None L858R Epidermal growth factor receptor
6JWLA 2.551 Inactive DFGin‑BLAminus in-in in-out YY3 Type1 696 - 1020 6 None L858R Epidermal growth factor receptor
4LQMA 2.5 Active DFGin‑BLAminus in-in in-in DJK Type1 697 - 1019 7 None L858R Epidermal growth factor receptor
7LGSA 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor
7LGSB 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor
7LGSC 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor
7LGSD 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor
7T4JA 2.2 Inactive DFGin‑BLAminus in-in in-out R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor
7T4JB 2.2 Active DFGin‑BLAminus in-in in-in R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor
8PO0A 2.523 Inactive DFGin‑BLAminus in-none in-out 2I6 Type1 695 - 1018 0 None None Epidermal growth factor receptor
4LRMA 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 696 - 999 0 None None Epidermal growth factor receptor
4LRMB 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 695 - 984 0 None None Epidermal growth factor receptor
4LRMC 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 694 - 983 0 None None Epidermal growth factor receptor
4LRMD 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 696 - 981 0 None None Epidermal growth factor receptor
4LRME 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 697 - 983 0 None None Epidermal growth factor receptor
9U8CA 3.5 Inactive DFGin‑BLAminus in-out in-out A1L8T Type1 696 - 989 0 None None Epidermal growth factor receptor
9U8CB 3.5 Active DFGin‑BLAminus in-in in-in A1L8T Type1 696 - 986 0 None None Epidermal growth factor receptor
9U8CC 3.5 Inactive DFGin‑BLAminus in-out in-in A1L8T Type1 696 - 980 0 None None Epidermal growth factor receptor
9U8CD 3.5 None DFGin‑BLAminus in-in in-none A1L8T Type1 696 - 987 4 None None Epidermal growth factor receptor
6JX0A 2.53 Active DFGin‑BLAminus in-in in-in YY3, YY3 Type1, Allosteric 701 - 989 0 None T790M Epidermal growth factor receptor
4G5JA 2.8 Active DFGin‑BLAminus in-in in-in 0WN, 0WM, 0WM Type1, Allosteric, Allosteric 696 - 1016 0 None None Epidermal growth factor receptor
8D73A 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor
8D73B 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor
8D76A 2.4 Active DFGin‑BLAminus in-in in-in QFO Type1.5_Back 703 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
8D76B 2.4 Active DFGin‑BLAminus in-in in-in QFO Type1.5_Back 702 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
6D8EA 2.537 None DFGin‑BLAminus in-in in-none FZP Type1.5_Back 696 - 1019 5 None None Epidermal growth factor receptor
9GL9A 2.147 Active DFGin‑BLAminus in-in in-in A1IMT Type1.5_Back 696 - 1019 4 None None Epidermal growth factor receptor
9FRDA 2.06 Active DFGin‑BLAminus in-in in-in A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
9GI9A 3.12 Active DFGin‑BLAminus in-in in-in A1ILZ Type1.5_Back 696 - 1018 7 None None Epidermal growth factor receptor
8F1ZA 2.4 Active DFGin‑BLAminus in-in in-in X9B Type1.5_Back 695 - 1018 0 None None Epidermal growth factor receptor
9QXNAAA 2.142 Active DFGin‑BLAminus in-in in-in A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
4RJ5A 3.1 None DFGin‑BLAminus in-in none-none 3QY Type1.5_Back 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CAQA 2.5 None DFGin‑BLAminus in-in in-none 4ZJ Type1.5_Back 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CASA 2.1 None DFGin‑BLAminus in-in in-none 4ZQ Type1.5_Back 696 - 1019 13 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5CAUA 2.25 None DFGin‑BLAminus in-in in-none 4ZR Type1.5_Back 696 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5HCYA 2.46 None DFGin‑BLAminus in-in in-none 60D Type1.5_Back 696 - 1019 13 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5HICA 2.6 None DFGin‑BLAminus in-in in-none 63N Type1.5_Back 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out FI3 Type1.5_Back 697 - 1018 9 None L858R Epidermal growth factor receptor
9DF2A 2.5 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor
9DF3A 1.68 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor
9DF4A 1.78 Active DFGin‑BLAminus in-in in-in A1A4E Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
9FQPA 2.495 Active DFGin‑BLAminus in-in in-in A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor
9FQSA 1.783 Active DFGin‑BLAminus in-in in-in A1IE0 Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
9GL7A 1.878 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor
9GL8A 1.632 Active DFGin‑BLAminus in-in in-in A1IMT Type1.5_Back 701 - 1021 0 None V948R Epidermal growth factor receptor
3W2OA 2.35 Inactive DFGin‑BLAminus out-out in-in 03P Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
3W2PA 2.05 Inactive DFGin‑BLAminus out-out in-in W2P Type1.5_Front 698 - 1018 0 None T790M,L858R Epidermal growth factor receptor
3W2QA 2.2 Inactive DFGin‑BLAminus out-out in-in HKI Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
5EDPA 2.9 Inactive DFGin‑BLAplus in-in none-none No_ligand No_ligand 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5XGMA 2.952 Inactive DFGin‑BLAplus in-in none-out 85X Type1 696 - 1019 16 None T790M Epidermal growth factor receptor
6JRJA 2.943 Inactive DFGin‑BLAplus in-out in-none C6O Type1 696 - 1018 15 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
5Y25A 3.102 Inactive DFGin‑BLAplus in-in none-none 8LU Type1 698 - 1017 16 None T790M,L858R Epidermal growth factor receptor
5EDRA 2.6 Inactive DFGin‑BLAplus in-in none-none 5N4 Type1 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5EM5A 2.65 Inactive DFGin‑BLAplus in-in none-none 5Q2 Type1 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none ANP Type1 696 - 1018 14 None None Epidermal growth factor receptor
6TFUB 2.0 Inactive DFGin‑BLAplus out-none none-out N7K Type1.5_Back 700 - 984 16 None T790M,V948R Epidermal growth factor receptor
5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none 5N3 Type1.5_Back 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out KY9 Type3 701 - 985 16 None None Epidermal growth factor receptor
8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out KY9 Type3 700 - 1019 8 None None Epidermal growth factor receptor
7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none 8BS Type1 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor
4RJ6A 2.7 Inactive DFGin‑BLBminus in-in in-none 3R0 Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
5EM6A 2.78 Inactive DFGin‑BLBminus in-in in-none 5Q3 Type1.5_Back 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none KXY Type3 701 - 1021 10 None L858R,V948R Epidermal growth factor receptor
6WXNA 1.76 Inactive DFGin‑BLBplus out-out none-out No_ligand No_ligand 699 - 1014 16 None T790M,V948R Epidermal growth factor receptor
7UKWA 2.6 Inactive DFGin‑BLBplus out-out out-out No_ligand No_ligand 702 - 1014 2 None T790M,V948R Epidermal growth factor receptor
7TVDA 2.96 Inactive DFGin‑BLBplus in-out none-out No_ligand No_ligand 698 - 1009 16 None None Epidermal growth factor receptor
5ZTOA 2.649 Inactive DFGin‑BLBplus in-in none-none 9JO Type1 697 - 1017 17 None T790M,C797S Epidermal growth factor receptor
6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1008 15 None T790M,V948R Epidermal growth factor receptor
6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 8 None T790M,V948R Epidermal growth factor receptor
6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1011 12 None T790M,V948R Epidermal growth factor receptor
6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor
6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 700 - 1014 11 None T790M,V948R Epidermal growth factor receptor
6V5NA 2.4 Inactive DFGin‑BLBplus out-out out-out QP7 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V5PA 2.3 Inactive DFGin‑BLBplus out-out out-out QP4 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1013 10 None T790M,V948R Epidermal growth factor receptor
6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 14 None T790M,V948R Epidermal growth factor receptor
8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none ANP Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1013 11 None T790M,V948R Epidermal growth factor receptor
8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor
8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none ANP Type1 702 - 1014 14 None T790M,V948R Epidermal growth factor receptor
4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none ANP Type1 701 - 1015 12 None T790M,V948R Epidermal growth factor receptor
5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 10 None T790M,V948R Epidermal growth factor receptor
7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none ANP Type1 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor
7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1005 15 None T790M,V948R Epidermal growth factor receptor
7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out VO7 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none ANP Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor
7KY0A 3.1 Inactive DFGin‑BLBplus out-out out-none XA4 Type1 701 - 1007 14 None T790M,V948R Epidermal growth factor receptor
6TFYA 1.7 Inactive DFGin‑BLBplus out-out none-out N7Z Type1 699 - 982 15 None T790M,V948R Epidermal growth factor receptor
7A6JB 2.0 Inactive DFGin‑BLBplus out-out out-out R2E Type1 699 - 984 15 None T790M,V948R Epidermal growth factor receptor
7ZYQA 2.1 Inactive DFGin‑BLBplus out-none out-out V58 Type1 700 - 984 15 None T790M,V948R Epidermal growth factor receptor
5FEEA 2.7 Inactive DFGin‑BLBplus in-in in-out 5X4 Type1 697 - 1018 5 None T790M Epidermal growth factor receptor
5GTYA 3.14 Inactive DFGin‑BLBplus out-out out-none 816 Type1 700 - 1014 11 None T790M Epidermal growth factor receptor
5GTYC 3.14 Inactive DFGin‑BLBplus out-out out-none 816 Type1 700 - 1013 15 None T790M Epidermal growth factor receptor
5GTYF 3.14 Inactive DFGin‑BLBplus out-none out-out 816 Type1 700 - 1013 13 None T790M Epidermal growth factor receptor
5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out ANP Type1 698 - 1015 12 None V948R Epidermal growth factor receptor
5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none ANP Type1 699 - 1014 13 None I706Q Epidermal growth factor receptor
6P1DB 2.4 Inactive DFGin‑BLBplus out-out out-out ANP, NQ1 Type1, Type3 702 - 1013 12 None None Epidermal growth factor receptor
6P1LA 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 701 - 1007 17 None T790M,V948R Epidermal growth factor receptor
6P1LC 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 702 - 1005 17 None T790M,V948R Epidermal growth factor receptor
6P1LD 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 702 - 1015 17 None T790M,V948R Epidermal growth factor receptor
6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none ANP, O57 Type1, Type3 699 - 1019 12 None T790M,V948R Epidermal growth factor receptor
6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none AMP, O57 Type1, Type3 698 - 1007 10 None T790M,V948R Epidermal growth factor receptor
6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in AMP, O57 Type1, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none AMP, O57 Type1, Type3 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor
6XL4A 2.06 Inactive DFGin‑BLBplus out-out out-none Q6K, NQ1 Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
6XL4D 2.06 Inactive DFGin‑BLBplus out-out out-none ANP, NQ1 Type1, Type3 700 - 1013 11 None T790M,V948R Epidermal growth factor receptor
8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none ANP, IXR Type1, Type3 702 - 1013 18 None T790M,V948R Epidermal growth factor receptor
8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none ANP, IXR Type1, Type3 702 - 1005 18 None T790M,V948R Epidermal growth factor receptor
5D41A 2.31 Inactive DFGin‑BLBplus out-out none-none ANP, 57N Type1, Type3 698 - 1014 17 None T790M,V948R Epidermal growth factor receptor
6DUKA 2.2 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 701 - 1006 0 None T790M,V948R Epidermal growth factor receptor
6DUKB 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 699 - 1007 13 None T790M,V948R Epidermal growth factor receptor
6DUKC 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 699 - 1007 14 None T790M,V948R Epidermal growth factor receptor
6DUKD 2.2 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
6DUKE 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 698 - 1007 12 None T790M,V948R Epidermal growth factor receptor
6DUKF 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 701 - 1009 11 None T790M,V948R Epidermal growth factor receptor
7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none 8BS, JBJ Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none 8BS, JBJ Type1, Type3 701 - 1007 15 None T790M,V948R Epidermal growth factor receptor
7JXKD 3.1 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none 8BS, JBJ Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none 8BS, JBJ Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXMB 2.192 Inactive DFGin‑BLBplus out-out none-none YY3, 9LL Type1, Type3 701 - 1012 16 None T790M,V948R Epidermal growth factor receptor
7JXMD 2.192 Inactive DFGin‑BLBplus out-out none-none ANP, 9LL Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
7JXPA 2.16 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
7JXPB 2.16 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
7JXPD 2.16 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7JXPF 2.16 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 701 - 1007 10 None T790M,V948R Epidermal growth factor receptor
7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor
7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none YY3, VNS Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
7LTXA 2.3 Inactive DFGin‑BLBplus out-out none-out ANP, YFA Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7LTXB 2.3 Inactive DFGin‑BLBplus out-out out-none ANP, YFA Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
7LTXC 2.3 Inactive DFGin‑BLBplus out-out none-none ANP, YFA Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7LTXD 2.3 Inactive DFGin‑BLBplus out-out out-none ANP, YFA Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor
8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1012 16 None T790M,V948R Epidermal growth factor receptor
8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 701 - 1011 17 None T790M,V948R Epidermal growth factor receptor
8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 17 None T790M,V948R Epidermal growth factor receptor
8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 700 - 1008 16 None T790M,V948R Epidermal growth factor receptor
8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 15 None T790M,V948R Epidermal growth factor receptor
6Z4BA 2.5 Inactive DFGin‑BLBplus out-none out-out Q6K, 9LL Type1, Type3 700 - 982 12 None T790M,V948R Epidermal growth factor receptor
6Z4BB 2.5 Inactive DFGin‑BLBplus out-out none-out Q6K, 9LL Type1, Type3 699 - 984 18 None T790M,V948R Epidermal growth factor receptor
6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out 8BS, 57N Type1, Type3 700 - 984 15 None T790M,V948R Epidermal growth factor receptor
7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none ANP, VNS Type1, Type3 700 - 1007 17 None L858R,V948R Epidermal growth factor receptor
5GNKA 1.796 Inactive DFGin‑BLBplus out-out out-out 80U Type1.5_Back 697 - 985 12 None T790M Epidermal growth factor receptor
6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 12 None T790M,V948R Epidermal growth factor receptor
6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TOV Type1.5_Back 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out YA6 Type1.5_Back 701 - 1009 17 None T790M,V948R Epidermal growth factor receptor
8FV4D 2.2 Inactive DFGin‑BLBplus out-out out-none YAA Type1.5_Back 701 - 1005 13 None T790M,V948R Epidermal growth factor receptor
6TFUA 2.0 Inactive DFGin‑BLBplus out-out out-none N7K Type1.5_Back 700 - 982 14 None T790M,V948R Epidermal growth factor receptor
6TFVA 1.5 Inactive DFGin‑BLBplus out-none none-none N7Q Type1.5_Back 700 - 985 16 None T790M,V948R Epidermal growth factor receptor
6TFVB 1.5 Inactive DFGin‑BLBplus out-out none-none N7Q Type1.5_Back 698 - 984 16 None T790M,V948R Epidermal growth factor receptor
6TFWA 2.0 Inactive DFGin‑BLBplus out-out out-none N7W Type1.5_Back 700 - 982 14 None T790M,V948R Epidermal growth factor receptor
6TFWB 2.0 Inactive DFGin‑BLBplus out-out none-out N7W Type1.5_Back 700 - 984 18 None T790M,V948R Epidermal growth factor receptor
6TFYB 1.7 Inactive DFGin‑BLBplus out-out none-out N7Z Type1.5_Back 699 - 984 17 None T790M,V948R Epidermal growth factor receptor
6TFZA 1.8 Inactive DFGin‑BLBplus out-none none-none N7B Type1.5_Back 701 - 982 16 None T790M,V948R Epidermal growth factor receptor
6TFZB 1.8 Inactive DFGin‑BLBplus out-none out-none N7B Type1.5_Back 700 - 984 14 None T790M,V948R Epidermal growth factor receptor
6TG0A 1.5 Inactive DFGin‑BLBplus out-out none-none N78 Type1.5_Back 700 - 985 18 None T790M,V948R Epidermal growth factor receptor
6TG0B 1.5 Inactive DFGin‑BLBplus out-out out-none N78 Type1.5_Back 698 - 984 11 None T790M,V948R Epidermal growth factor receptor
6TG1A 1.6 Inactive DFGin‑BLBplus out-out none-out N82 Type1.5_Back 699 - 984 18 None T790M,V948R Epidermal growth factor receptor
6TG1B 1.6 Inactive DFGin‑BLBplus out-none none-out N82 Type1.5_Back 698 - 984 16 None T790M,V948R Epidermal growth factor receptor
2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out HKI Type1.5_Back 699 - 982 11 None T790M Epidermal growth factor receptor
5GTYB 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 700 - 1014 12 None T790M Epidermal growth factor receptor
5GTYD 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 701 - 1014 12 None T790M Epidermal growth factor receptor
5GTYE 3.14 Inactive DFGin‑BLBplus out-none out-out 816 Type1.5_Back 701 - 1014 12 None T790M Epidermal growth factor receptor
5GTYG 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 699 - 1014 12 None T790M Epidermal growth factor receptor
5GTYH 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 700 - 1016 12 None T790M Epidermal growth factor receptor
3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none W2R Type1.5_Back 698 - 1017 14 None T790M,L858R Epidermal growth factor receptor
2RGPA 2.0 Inactive DFGin‑BLBplus out-out out-none HYZ Type1.5_Back 702 - 1016 8 None None Epidermal growth factor receptor
3BELA 2.3 Inactive DFGin‑BLBplus out-out out-none POX Type1.5_Back 702 - 1015 8 None None Epidermal growth factor receptor
8PO4A 1.621 Inactive DFGin‑BLBplus out-out out-out 26X Type1.5_Back 700 - 1014 8 None V948R Epidermal growth factor receptor
3LZBA 2.7 Inactive DFGin‑BLBplus out-out none-out ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor
3LZBB 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor
3LZBC 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 704 - 983 16 None V948R Epidermal growth factor receptor
3LZBD 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor
3POZA 1.5 Inactive DFGin‑BLBplus out-out out-none 03P Type1.5_Back 701 - 1017 7 None None Epidermal growth factor receptor
3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out W2R Type1.5_Back 701 - 1019 12 None None Epidermal growth factor receptor
3W32A 1.8 Inactive DFGin‑BLBplus out-out out-in W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
3W33A 1.7 Inactive DFGin‑BLBplus out-out out-none W19 Type1.5_Back 701 - 1018 12 None None Epidermal growth factor receptor
1XKKA 2.4 Inactive DFGin‑BLBplus out-out out-out FMM Type1.5_Back 702 - 1018 8 None None Epidermal growth factor receptor
8PO1A 2.11 Inactive DFGin‑BLBplus out-out out-none 2EI Type1.5_Back 699 - 984 12 None V948R Epidermal growth factor receptor
8PO2A 2.28 Inactive DFGin‑BLBplus out-out out-none 26X Type1.5_Back 705 - 984 12 None V948R Epidermal growth factor receptor
8PO2B 2.28 Inactive DFGin‑BLBplus out-out out-none 26X Type1.5_Back 702 - 984 12 None V948R Epidermal growth factor receptor
9EWSA 2.435 Inactive DFGin‑BLBplus out-out out-none A1H7N Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor
9EWTA 3.019 Inactive DFGin‑BLBplus out-out out-out A1H7O Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor
9EWTB 3.019 Inactive DFGin‑BLBplus out-out out-none A1H7O Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor
9GC4A 2.415 Inactive DFGin‑BLBplus out-out out-out A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
9GC4B 2.415 Inactive DFGin‑BLBplus out-out out-out A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
9HBOA 2.45 Inactive DFGin‑BLBplus out-none out-out A1IUK Type1.5_Back 702 - 986 11 None V948R Epidermal growth factor receptor
9HBOB 2.45 Inactive DFGin‑BLBplus out-none out-out A1IUK Type1.5_Back 702 - 985 6 None V948R Epidermal growth factor receptor
6WAKC 2.4 Inactive DFGin‑BLBplus out-out none-out TQA Type1.5_Front 701 - 1014 15 None T790M,V948R Epidermal growth factor receptor
6WXNC 1.76 Inactive DFGin‑BLBplus out-out none-out UEJ Type1.5_Front 701 - 1014 16 None T790M,V948R Epidermal growth factor receptor
6WXND 1.76 Inactive DFGin‑BLBplus out-out out-none UEJ Type1.5_Front 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor
8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out IXC Type1.5_Front 702 - 1007 15 None T790M,V948R Epidermal growth factor receptor
7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type1.5_Front, Type1 702 - 1002 15 None T790M,V948R Epidermal growth factor receptor
5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out 9LL Type3 702 - 985 17 None T790M,C797S,V948R Epidermal growth factor receptor
8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out KY9 Type3 702 - 990 17 None L858R,V948R Epidermal growth factor receptor
6P1DC 2.4 Inactive DFGin‑BLBplus out-out out-none NQ1, ANP Type3, Type1 702 - 1006 13 None None Epidermal growth factor receptor
6P1DD 2.4 Inactive DFGin‑BLBplus out-out out-none NQ1, ANP Type3, Type1 701 - 1008 13 None None Epidermal growth factor receptor
6XL4B 2.06 Inactive DFGin‑BLBplus out-out none-none NQ1, Q6K Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXPC 2.16 Inactive DFGin‑BLBplus out-out none-none JBJ, YY3 Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXPE 2.16 Inactive DFGin‑BLBplus out-out none-none JBJ, YY3 Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out VNS, ANP Type3, Type1 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor
7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none VNS, ANP Type3, Type1 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor
7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor
7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 703 - 1004 15 None T790M,V948R Epidermal growth factor receptor
7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type3, Type1 702 - 1003 17 None T790M,V948R Epidermal growth factor receptor
7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out 57N, 7G9 Type3, Type1 700 - 984 17 None T790M,V948R Epidermal growth factor receptor
7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out 57N, 7G9 Type3, Type1 699 - 984 18 None T790M,V948R Epidermal growth factor receptor
7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1007 16 None L858R,V948R Epidermal growth factor receptor
7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1008 17 None L858R,V948R Epidermal growth factor receptor
7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor
7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out VNS, YY3 Type3, Type1 701 - 1007 15 None L858R,V948R Epidermal growth factor receptor
7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 703 - 1007 16 None L858R,V948R Epidermal growth factor receptor
7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor
6XL4C 2.06 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 700 - 1011 7 None T790M,V948R Epidermal growth factor receptor
7UKWD 2.6 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 702 - 1012 6 None T790M,V948R Epidermal growth factor receptor
8FV4B 2.2 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 702 - 1007 3 None T790M,V948R Epidermal growth factor receptor
2RFDA 3.6 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 11 None K823E Epidermal growth factor receptor
2RFDB 3.6 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 8 None K823E Epidermal growth factor receptor
2RFEA 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 702 - 1002 8 None K823E Epidermal growth factor receptor
2RFEB 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1012 11 None K823E Epidermal growth factor receptor
2RFEC 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 702 - 983 11 None K823E Epidermal growth factor receptor
2RFED 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 11 None K823E Epidermal growth factor receptor
6P1DA 2.4 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1021 13 None None Epidermal growth factor receptor
6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none QP1 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor
6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 700 - 1014 14 None T790M,V948R Epidermal growth factor receptor
6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor
6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor
6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1009 15 None T790M,V948R Epidermal growth factor receptor
6V5NB 2.4 Inactive DFGin‑BLBtrans out-out out-none QP7 Type1 700 - 1008 12 None T790M,V948R Epidermal growth factor receptor
6V5NC 2.4 Inactive DFGin‑BLBtrans out-out out-out QP7 Type1 701 - 1007 13 None T790M,V948R Epidermal growth factor receptor
6V5ND 2.4 Inactive DFGin‑BLBtrans out-out out-out QP7 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
6V5PB 2.3 Inactive DFGin‑BLBtrans out-out out-out QP4 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor
6V5PC 2.3 Inactive DFGin‑BLBtrans out-out out-none QP4 Type1 701 - 1008 13 None T790M,V948R Epidermal growth factor receptor
6V5PD 2.3 Inactive DFGin‑BLBtrans out-out out-out QP4 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
6WAKB 2.4 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1020 4 None T790M,V948R Epidermal growth factor receptor
6WXNB 1.76 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 11 None T790M,V948R Epidermal growth factor receptor
7UKWB 2.6 Inactive DFGin‑BLBtrans out-out none-none ZRT Type1 702 - 1010 17 None T790M,V948R Epidermal growth factor receptor
7UKWC 2.6 Inactive DFGin‑BLBtrans out-out out-none ZRT Type1 700 - 1005 13 None T790M,V948R Epidermal growth factor receptor
8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 12 None T790M,V948R Epidermal growth factor receptor
8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1008 12 None T790M,V948R Epidermal growth factor receptor
8FV4A 2.2 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 701 - 1013 13 None T790M,V948R Epidermal growth factor receptor
8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor
8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1008 13 None T790M,V948R Epidermal growth factor receptor
8TO4A 2.99 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 13 None T790M,V948R Epidermal growth factor receptor
4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 699 - 1007 12 None T790M,V948R Epidermal growth factor receptor
4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 698 - 1022 12 None T790M,V948R Epidermal growth factor receptor
4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1013 13 None T790M,V948R Epidermal growth factor receptor
5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO Type1 700 - 1015 13 None T790M,V948R Epidermal growth factor receptor
5X2CA 2.05 Inactive DFGin‑BLBtrans out-out out-out 7XR Type1 700 - 1015 12 None T790M,V948R Epidermal growth factor receptor
5X2CB 2.05 Inactive DFGin‑BLBtrans out-out out-out 7XR Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor
5X2FA 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 700 - 1014 12 None T790M,V948R Epidermal growth factor receptor
5X2FB 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 699 - 1010 0 None T790M,V948R Epidermal growth factor receptor
5X2FC 2.2 Inactive DFGin‑BLBtrans out-out out-none 7XU Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
5X2FD 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 697 - 1014 7 None T790M,V948R Epidermal growth factor receptor
7JXIA 3.0 Inactive DFGin‑BLBtrans out-out none-none 8BS Type1 700 - 1006 17 None T790M,V948R Epidermal growth factor receptor
7JXID 3.0 Inactive DFGin‑BLBtrans out-out out-none 8BS Type1 702 - 1006 13 None T790M,V948R Epidermal growth factor receptor
7JXLA 2.4 Inactive DFGin‑BLBtrans out-out out-none VO7 Type1 701 - 1013 14 None T790M,V948R Epidermal growth factor receptor
7JXMA 2.192 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7KY0B 3.1 Inactive DFGin‑BLBtrans out-out out-out XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7KY0D 3.1 Inactive DFGin‑BLBtrans out-out out-none XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7U98B 3.42 Inactive DFGin‑BLBtrans out-out out-out M1O Type1 701 - 1005 12 None T790M,V948R Epidermal growth factor receptor
7U98C 3.42 Inactive DFGin‑BLBtrans out-out out-out M1O Type1 702 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7U98D 3.42 Inactive DFGin‑BLBtrans out-out none-out M1O Type1 701 - 1007 16 None T790M,V948R Epidermal growth factor receptor
8F1WA 3.2 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 701 - 1007 4 None T790M,V948R Epidermal growth factor receptor
8F1WB 3.2 Inactive DFGin‑BLBtrans out-out out-none R2E Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
8F1WC 3.2 Inactive DFGin‑BLBtrans out-out out-none R2E Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
8F1WD 3.2 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 700 - 1007 4 None T790M,V948R Epidermal growth factor receptor
6Z4DA 2.0 Inactive DFGin‑BLBtrans out-out out-out 8BS Type1 701 - 984 13 None T790M,V948R Epidermal growth factor receptor
7A6JA 2.0 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 699 - 982 14 None T790M,V948R Epidermal growth factor receptor
7A6KA 2.0 Inactive DFGin‑BLBtrans out-out out-out R28 Type1 700 - 984 14 None T790M,V948R Epidermal growth factor receptor
7A6KB 2.0 Inactive DFGin‑BLBtrans out-none none-out R28 Type1 700 - 982 17 None T790M,V948R Epidermal growth factor receptor
7A6KC 2.0 Inactive DFGin‑BLBtrans out-none none-out R28 Type1 700 - 984 17 None T790M,V948R Epidermal growth factor receptor
7A6KD 2.0 Inactive DFGin‑BLBtrans out-out none-out R28 Type1 702 - 984 18 None T790M,V948R Epidermal growth factor receptor
4I24A 1.8 Inactive DFGin‑BLBtrans out-out out-out 1C9 Type1 700 - 1014 13 None T790M Epidermal growth factor receptor
4I24B 1.8 Inactive DFGin‑BLBtrans out-out out-out 1C9 Type1 700 - 1014 11 None T790M Epidermal growth factor receptor
5YU9A 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 700 - 1017 12 None T790M Epidermal growth factor receptor
5YU9B 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 699 - 1011 13 None T790M Epidermal growth factor receptor
5YU9C 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 697 - 1021 12 None T790M Epidermal growth factor receptor
5YU9D 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 700 - 1012 13 None T790M Epidermal growth factor receptor
4I22A 1.71 Inactive DFGin‑BLBtrans out-out out-out IRE Type1 700 - 1014 13 None T790M,L858R,V948R Epidermal growth factor receptor
8PO4B 1.621 Inactive DFGin‑BLBtrans out-out out-out ATP Type1 700 - 1014 13 None V948R Epidermal growth factor receptor
2GS7A 2.6 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 703 - 1012 4 None V948R Epidermal growth factor receptor
2GS7B 2.6 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1016 3 None V948R Epidermal growth factor receptor
3GT8A 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1014 15 None V948R Epidermal growth factor receptor
3GT8B 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1007 15 None V948R Epidermal growth factor receptor
3GT8C 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 699 - 1007 13 None V948R Epidermal growth factor receptor
3GT8D 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1010 15 None V948R Epidermal growth factor receptor
5CNOA 1.55 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 700 - 1015 11 None V948R Epidermal growth factor receptor
9GC6A 1.901 Inactive DFGin‑BLBtrans out-out out-none A1IZ9 Type1 698 - 1014 14 None V948R Epidermal growth factor receptor
9GC6B 1.901 Inactive DFGin‑BLBtrans out-out out-none A1IZ9 Type1 698 - 1014 14 None V948R Epidermal growth factor receptor
9GDVA 2.218 Inactive DFGin‑BLBtrans out-none out-none Q6K Type1 702 - 985 15 None V948R Epidermal growth factor receptor
9GDVB 2.218 Inactive DFGin‑BLBtrans out-none none-out Q6K Type1 702 - 985 17 None V948R Epidermal growth factor receptor
4HJOA 2.75 Inactive DFGin‑BLBtrans out-out out-out AQ4 Type1 703 - 984 0 None V948R Epidermal growth factor receptor
5CNNB 1.9 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 700 - 1014 11 None I706Q Epidermal growth factor receptor
6JXTA 2.307 Inactive DFGin‑BLBtrans out-out out-in YY3 Type1 697 - 984 2 None E865A,E866A,K867A Epidermal growth factor receptor
5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none 7XO, ANP Type1, Allosteric 700 - 1011 13 None T790M,V948R Epidermal growth factor receptor
5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO, ANP Type1, Type1 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor
9GC5A 1.909 Inactive DFGin‑BLBtrans out-out out-none A1IZ8 Type1.5_Back 699 - 1012 14 None V948R Epidermal growth factor receptor
9GC5B 1.909 Inactive DFGin‑BLBtrans out-out out-none A1IZ8 Type1.5_Back 699 - 1012 14 None V948R Epidermal growth factor receptor
8PO3A 2.13 Inactive DFGin‑BLBtrans out-out out-out 2II Type1.5_Front 706 - 1001 13 None V948R Epidermal growth factor receptor
8EMEA 3.32 Inactive DFGin‑None out-out none-none No_ligand No_ligand 700 - 1007 21 None T790M,V948R Epidermal growth factor receptor
3GOPA 2.8 Inactive DFGin‑None in-na none-none No_ligand No_ligand 676 - 1018 18 None K745M Epidermal growth factor receptor
7JXIB 3.0 Inactive DFGin‑None out-out none-none 8BS Type1 702 - 1004 17 None T790M,V948R Epidermal growth factor receptor
7KY0C 3.1 Inactive DFGin‑None out-out out-none XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7U98A 3.42 Inactive DFGin‑None out-out out-none M1O Type1 701 - 1007 14 None T790M,V948R Epidermal growth factor receptor
7ZYQB 2.1 Inactive DFGin‑None out-out none-out V58 Type1 700 - 984 19 None T790M,V948R Epidermal growth factor receptor
4RIWB 3.1 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor
4RIWD 3.1 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
4RIXB 3.1 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor
4RIXD 3.1 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
4RIYB 2.981 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor
4RIYD 2.981 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
2JIVA 3.5 Inactive DFGin‑None out-out out-none HKI Type1.5_Back 700 - 984 14 None T790M Epidermal growth factor receptor
8H7XB 3.404 Inactive DFGinter‑None in-in out-none No_ligand No_ligand 697 - 1018 7 None T790M,C797S Epidermal growth factor receptor
5XGNB 3.0 Inactive DFGinter‑None in-in out-out No_ligand No_ligand 697 - 1019 4 None T790M,C797S Epidermal growth factor receptor
2JITB 3.1 Inactive DFGinter‑None in-in out-in No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor
2JIUB 3.05 Inactive DFGinter‑None in-in in-in No_ligand No_ligand 695 - 1004 0 None T790M Epidermal growth factor receptor
4G5PB 3.17 Inactive DFGinter‑None in-in out-out No_ligand No_ligand 697 - 1018 8 None T790M Epidermal growth factor receptor
3IKAB 2.9 Inactive DFGinter‑None in-in out-in No_ligand No_ligand 697 - 1017 2 None T790M Epidermal growth factor receptor
4WD5B 3.3 Inactive DFGinter‑None in-out out-out No_ligand No_ligand 697 - 1016 5 None T790M Epidermal growth factor receptor
5UWDA 3.06 Inactive DFGinter‑None out-out out-out 8OV Type1 702 - 984 12 None T790M,L858R,V948R Epidermal growth factor receptor
2RF9A 3.5 Inactive DFGout‑BBAminus out-none in-out No_ligand No_ligand 699 - 983 2 None None Epidermal growth factor receptor
4ZJVA 2.7 Inactive DFGout‑BBAminus out-out in-in No_ligand No_ligand 703 - 985 0 None None Epidermal growth factor receptor
4ZJVB 2.7 Inactive DFGout‑BBAminus out-out in-in No_ligand No_ligand 703 - 982 0 None None Epidermal growth factor receptor
5HG5A 1.52 Inactive DFGout‑BBAminus out-out in-in 633 Type1 700 - 1001 0 None T790M,L858R,V948R Epidermal growth factor receptor
5HG7A 1.85 Inactive DFGout‑BBAminus out-out in-in 630 Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor
5HG8A 1.42 Inactive DFGout‑BBAminus out-out in-in 634 Type1 700 - 999 0 None T790M,L858R,V948R Epidermal growth factor receptor
5HG9A 2.15 Inactive DFGout‑BBAminus out-out in-in 63A Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
5U8LA 1.6 Inactive DFGout‑BBAminus out-out in-in O44 Type1 702 - 990 0 None None Epidermal growth factor receptor
5UG8A 1.46 Inactive DFGout‑BBAminus out-out in-in 8BP Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
5UGAA 1.82 Inactive DFGout‑BBAminus out-out in-in 8BM Type1 703 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
4I1ZA 3.0 Inactive DFGout‑None out-out in-in No_ligand No_ligand 701 - 987 0 None T790M,L858R,V948R Epidermal growth factor receptor
4I21A 3.37 Inactive DFGout‑None out-out in-in No_ligand No_ligand 703 - 1019 0 None T790M,L858R Epidermal growth factor receptor
4I21B 3.37 Inactive DFGout‑None out-out in-in No_ligand No_ligand 703 - 1020 0 None T790M,L858R Epidermal growth factor receptor
2RF9B 3.5 Inactive DFGout‑None out-none in-out No_ligand No_ligand 701 - 985 6 None None Epidermal growth factor receptor
4I20A 3.34 Inactive DFGout‑None out-out in-in No_ligand No_ligand 701 - 987 0 None L858R,V948R Epidermal growth factor receptor

TYR_EGFR (Epidermal growth factor receptor)

Total number of chains: 513
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 197 AF-P00533-K1A
DFGin BLAplus 11 8A2AA
DFGin ABAminus 5 3IKAA
DFGin BLBminus 4 8A2DA
DFGin BLBplus 166 6V66D
DFGin BLBtrans 92 6V66A
DFGin None 13 4RIYD
DFGinter None 8 2JIUB
DFGout BBAminus 12 5HG8A
DFGout None 5 4I1ZA

Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
EGFR_HUMAN 3IKAA 2.9 Inactive DFGin‑ABAminus in-in in-in 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ER2A 2.662 Inactive DFGin‑ABAminus in-in in-in JAU Type1 697 - 1018 7 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8KFQA 3.22 Inactive DFGin‑ABAminus in-in in-none VUZ Type1 697 - 1018 14 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none YUN Type1 697 - 1017 13 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none YUN Type1 698 - 1017 14 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV4A 2.2 Active DFGin‑BLAminus in-in in-in PE5, MWU Allosteric, Type1 696 - 1020 3 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV6A 2.2 Active DFGin‑BLAminus in-in in-in PE5, N86 Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV7A 2.69 Active DFGin‑BLAminus in-in in-in PE5, N8O Allosteric, Type1 696 - 1019 6 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV8A 2.4 Active DFGin‑BLAminus in-in in-in PE5, N99 Allosteric, Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV9A 2.5 Active DFGin‑BLAminus in-in in-in PE5, N9L Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9BY6A 2.551 Active DFGin‑BLAminus in-in in-in PDO, Q6K Allosteric, Type1 698 - 1009 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV1A 2.4 Active DFGin‑BLAminus in-in in-in PE5, N6N Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV3A 2.4 Active DFGin‑BLAminus in-in in-in PE5, MWU Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV5A 2.2 Active DFGin‑BLAminus in-in in-in PE5, N7C Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9BY4A 2.307 Active DFGin‑BLAminus in-in in-in PDO, Q6K, PDO, PDO Allosteric, Type1, Allosteric, Type1 696 - 1010 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JITA 3.1 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3UG1A 2.75 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN AF-P00533-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN AF-P00533-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2J5EA 3.1 Inactive DFGin‑BLAminus in-in in-out No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2GS2A 2.8 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2GS6A 2.6 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4WRGA 1.9 Inactive DFGin‑BLAminus in-out in-none No_ligand No_ligand 696 - 1019 2 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7SI1A 1.6 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 695 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4TKSA 3.202 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 697 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 1M14A 2.6 Inactive DFGin‑BLAminus in-out in-out No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2EB2A 2.5 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 696 - 1019 1 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4R3PA 2.905 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4R3RA 3.25 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CZHA 2.8 Inactive DFGin‑BLAminus in-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CZIA 2.6 Inactive DFGin‑BLAminus out-out in-in No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9U8CE 3.5 Inactive DFGin‑BLAminus in-none in-out No_ligand No_ligand 696 - 982 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8H7XA 3.404 Active DFGin‑BLAminus in-in in-in 6GY Type1 697 - 1019 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5XGNA 3.0 Inactive DFGin‑BLAminus in-in in-out 85X Type1 697 - 1020 0 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JRXA 2.201 Active DFGin‑BLAminus in-in in-in 9JO Type1 696 - 1017 3 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5J9YA 2.8 Active DFGin‑BLAminus in-in in-in 6HL Type1 697 - 1019 3 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8EMEB 3.32 Inactive DFGin‑BLAminus out-out none-none ZNL Type1 702 - 1007 19 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5J9ZA 2.5 None DFGin‑BLAminus in-in in-none 6HJ Type1 696 - 1020 15 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6IA 2.4 Inactive DFGin‑BLAminus out-out in-out R1W Type1 703 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2KA 3.201 Active DFGin‑BLAminus in-in in-in 0UN Type1 696 - 1020 6 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JIUA 3.05 Inactive DFGin‑BLAminus in-out in-in AEE Type1 696 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5FEQA 3.4 Inactive DFGin‑BLAminus in-in in-out 5XH Type1 697 - 1017 5 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus in-in in-in 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GMPA 2.797 Inactive DFGin‑BLAminus in-in in-out F62 Type1 696 - 1019 11 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTZA 2.999 Inactive DFGin‑BLAminus in-in in-out 81C Type1 697 - 1020 7 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5XDKA 2.346 Active DFGin‑BLAminus in-in in-in 8JC Type1 696 - 1018 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JX4A 2.531 None DFGin‑BLAminus in-in in-none YY3 Type1 696 - 1018 8 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4WD5A 3.3 Inactive DFGin‑BLAminus out-out in-out 3LH Type1 694 - 1021 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5Y9TA 3.25 Active DFGin‑BLAminus in-in in-in 8RC Type1 697 - 1020 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3UG2A 2.5 Inactive DFGin‑BLAminus in-out in-in IRE Type1 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3VJNA 2.34 Inactive DFGin‑BLAminus in-out in-in ANP Type1 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7VRAA 2.41 None DFGin‑BLAminus in-in in-none I0A Type1 696 - 1018 11 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7VREA 2.507 None DFGin‑BLAminus in-in in-none 7VH Type1 696 - 1018 8 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6S89A 2.701 Active DFGin‑BLAminus in-in in-in L0Q Type1 697 - 1017 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6S8AA 2.6 Active DFGin‑BLAminus in-in in-in L0N Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ZYMA 2.5 Active DFGin‑BLAminus in-in in-in 6GY Type1 696 - 1020 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ZYNA 2.3 Active DFGin‑BLAminus in-in in-in 0UN Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ZYPA 2.8 None DFGin‑BLAminus in-none in-in R25 Type1 695 - 1019 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9JQ1A 3.02 Active DFGin‑BLAminus in-in in-in A1ECU Type1 697 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7OXBA 2.56 Active DFGin‑BLAminus in-in in-in 35Z Type1 696 - 1019 6 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9KLWA 2.67 None DFGin‑BLAminus in-in in-none A1L53 Type1 696 - 1019 13 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8DSWA 2.39 None DFGin‑BLAminus none-none in-none ANP Type1 696 - 1017 9 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8WD4A 2.55 Active DFGin‑BLAminus in-in in-in W7W Type1 696 - 1019 11 None T790M,C797S,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6LUBA 2.315 Active DFGin‑BLAminus in-in in-in EUX Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6LUDA 2.05 Active DFGin‑BLAminus in-in in-in YY3 Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9D3VA 2.32 Inactive DFGin‑BLAminus in-in in-out A1A5V Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9D3WA 2.53 Active DFGin‑BLAminus in-in in-in A1A5L Type1 696 - 1017 11 None C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HVAA 2.77 Active DFGin‑BLAminus in-in in-in N9R Type1 696 - 1020 4 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JZ0A 2.86 Active DFGin‑BLAminus in-in in-in CKO Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITWA 2.88 Inactive DFGin‑BLAminus in-out in-in ITQ Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus in-in in-in ANP Type1 697 - 1019 4 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITYA 3.42 None DFGin‑BLAminus in-in in-none IRE Type1 697 - 1019 10 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2J5FA 3.0 None DFGin‑BLAminus in-in in-none DJK Type1 696 - 1020 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2J6MA 3.1 Active DFGin‑BLAminus in-in in-in AEE Type1 697 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6VH4A 2.8 Active DFGin‑BLAminus in-in in-in QQM Type1 696 - 1019 3 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus in-in in-none QQJ Type1 696 - 1019 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus in-in in-none QP1 Type1 696 - 1019 5 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8G63A 2.5 None DFGin‑BLAminus in-in in-none YXT Type1 696 - 1017 14 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9MSRA 1.93 None DFGin‑BLAminus in-in in-none A1BRC Type1 697 - 1017 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9MSSA 2.09 Active DFGin‑BLAminus in-in in-in A1BYO Type1 697 - 1017 6 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9MSTA 2.57 Active DFGin‑BLAminus in-in in-in A1BYN Type1 696 - 1017 5 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9NHWA 2.73 None DFGin‑BLAminus in-in in-none A1BYD Type1 698 - 1017 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9NISA 2.23 None DFGin‑BLAminus in-in in-none A1BYK Type1 696 - 1016 10 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9NJ7A 2.53 None DFGin‑BLAminus in-in in-none A1BYL Type1 698 - 1017 15 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9NJNA 2.24 None DFGin‑BLAminus in-in in-none A1BYS Type1 698 - 1017 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus in-in in-none VO7 Type1 697 - 1018 16 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9OS6A 2.75 None DFGin‑BLAminus in-in in-none A1CEA Type1 697 - 1017 14 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9OU9A 2.1 None DFGin‑BLAminus in-in in-none A1CEL Type1 697 - 1017 14 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9PMZA 2.33 None DFGin‑BLAminus in-in in-none A1CI6 Type1 696 - 1017 14 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9Q0SA 2.46 None DFGin‑BLAminus in-in in-none A1CNG Type1 696 - 1017 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9H46A 3.163 Inactive DFGin‑BLAminus in-in in-out A1ISA Type1 696 - 1019 11 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus in-in in-none ZRT Type1 696 - 1018 6 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5FEDA 2.651 Active DFGin‑BLAminus in-in in-in 5X4 Type1 697 - 1017 4 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7T4IA 2.61 Active DFGin‑BLAminus in-in in-in R28 Type1 697 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4JQ7A 2.73 Inactive DFGin‑BLAminus in-in in-out KJQ Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4JQ8A 2.83 Inactive DFGin‑BLAminus in-in in-out KJ8 Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4JR3A 2.7 Inactive DFGin‑BLAminus in-in in-out KJR Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4JRVA 2.8 Inactive DFGin‑BLAminus in-in in-out KJV Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LI5A 2.64 Active DFGin‑BLAminus in-in in-in 1WY Type1 696 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I23A 2.8 Active DFGin‑BLAminus in-in in-in 1C9 Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UGBA 2.53 Active DFGin‑BLAminus in-in in-in 8BM Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7AEIA 2.65 Active DFGin‑BLAminus in-in in-in R85 Type1 697 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PNZA 2.51 Inactive DFGin‑BLAminus in-out in-in 2I0 Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9FZRA 1.991 Active DFGin‑BLAminus in-in in-in A1IHC Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9FZSA 2.121 Active DFGin‑BLAminus in-in in-in A1IHD Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5JEBA 3.298 Inactive DFGin‑BLAminus in-in in-out 6JS Type1 699 - 999 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4WKQA 1.85 Active DFGin‑BLAminus in-in in-in IRE Type1 696 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZAUA 2.8 None DFGin‑BLAminus in-in in-none YY3 Type1 698 - 1017 5 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8SC7A 1.984 Active DFGin‑BLAminus in-in in-in D0D Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9KL4A 2.32 Active DFGin‑BLAminus in-in in-in A1L53 Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CAVA 2.73 Active DFGin‑BLAminus in-in in-in 4ZQ Type1 697 - 1020 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EM8A 2.8 Active DFGin‑BLAminus in-in in-in 5Q4 Type1 696 - 1018 2 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7KXZA 2.4 Active DFGin‑BLAminus in-in in-in XA4 Type1 696 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U99A 2.5 Active DFGin‑BLAminus in-in in-in M0R Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U9AA 2.6 None DFGin‑BLAminus in-in in-none M19 Type1 695 - 1018 4 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1HA 2.8 Active DFGin‑BLAminus in-in in-in X9H Type1 697 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1XA 2.3 Active DFGin‑BLAminus in-in in-in R28 Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1YA 2.75 Active DFGin‑BLAminus in-in in-in R2E Type1 696 - 1019 3 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TJLA 2.7 Active DFGin‑BLAminus in-in in-in HZ6 Type1 696 - 1019 2 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HV2A 2.8 Active DFGin‑BLAminus in-in in-in MWU Type1 697 - 1019 5 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 1M17A 2.6 Inactive DFGin‑BLAminus in-in in-out AQ4 Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7B85A 2.5 None DFGin‑BLAminus in-in in-none R28 Type1 697 - 1020 2 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3VJOA 2.64 Inactive DFGin‑BLAminus in-out in-in ANP Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7AEMA 2.65 Active DFGin‑BLAminus in-in in-in 6GY Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus in-in in-none ANP Type1 696 - 1019 9 None G719S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITOA 3.25 None DFGin‑BLAminus in-in in-none IRE Type1 696 - 1019 9 None G719S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITPA 2.74 Active DFGin‑BLAminus in-in in-in AEE Type1 697 - 1018 0 None G719S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITQA 2.68 Active DFGin‑BLAminus in-in in-in ITQ Type1 697 - 1018 0 None G719S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6S9BA 3.25 None DFGin‑BLAminus in-in in-none L1H Type1 697 - 1019 12 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6S9CA 2.73 None DFGin‑BLAminus in-in in-none L1K Type1 696 - 1019 12 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6S9DA 2.67 Active DFGin‑BLAminus in-in in-in L3Z Type1 696 - 1017 11 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8HY7A 2.91 Inactive DFGin‑BLAminus in-out in-none NSO Type1 696 - 1019 14 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RJ4A 2.78 None DFGin‑BLAminus in-in in-none 3QW Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RJ7A 2.55 None DFGin‑BLAminus in-in in-none 3R1 Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus in-in in-none 3QS Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5C8KA 3.0 None DFGin‑BLAminus in-in in-none 4YV Type1 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5C8MA 2.9 None DFGin‑BLAminus in-in in-none 4YW Type1 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5C8NA 2.401 None DFGin‑BLAminus in-in in-none 4YX Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CALA 2.7 None DFGin‑BLAminus in-in in-none 4Z8 Type1 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CANA 2.8 None DFGin‑BLAminus in-in in-none 4ZB Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CAOA 2.6 None DFGin‑BLAminus in-in none-none 4ZG Type1 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CAPA 2.4 None DFGin‑BLAminus in-in in-none 4ZH Type1 697 - 1019 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EM7A 2.81 None DFGin‑BLAminus in-in in-none 5Q4 Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HCXA 2.6 None DFGin‑BLAminus in-in in-none 60B Type1 696 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HCZA 2.62 None DFGin‑BLAminus in-in in-none 60E Type1 696 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HIBA 2.85 Active DFGin‑BLAminus in-in in-in 63M Type1 696 - 1018 5 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JRKA 2.796 Inactive DFGin‑BLAminus in-out in-none C6O Type1 696 - 1018 15 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITTA 2.73 None DFGin‑BLAminus in-in in-none AEE Type1 697 - 1019 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITUA 2.8 Inactive DFGin‑BLAminus in-out in-none ITQ Type1 696 - 1019 10 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus in-in in-none ANP Type1 696 - 1019 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2ITZA 2.8 Inactive DFGin‑BLAminus in-out in-none IRE Type1 697 - 1020 10 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X26A 2.951 None DFGin‑BLAminus in-in in-none 7XO Type1 697 - 1020 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus in-in in-none 7XR Type1 697 - 1020 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus in-in in-none 7XU Type1 697 - 1020 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5XDLA 2.7 None DFGin‑BLAminus in-in in-none 8JC Type1 696 - 1018 15 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JWLA 2.551 Inactive DFGin‑BLAminus in-in in-out YY3 Type1 696 - 1020 6 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LQMA 2.5 Active DFGin‑BLAminus in-in in-in DJK Type1 697 - 1019 7 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LGSA 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LGSB 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LGSC 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LGSD 3.1 Active DFGin‑BLAminus in-in in-in Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7T4JA 2.2 Inactive DFGin‑BLAminus in-in in-out R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7T4JB 2.2 Active DFGin‑BLAminus in-in in-in R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO0A 2.523 Inactive DFGin‑BLAminus in-none in-out 2I6 Type1 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LRMA 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 696 - 999 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LRMB 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 695 - 984 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LRMC 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 694 - 983 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LRMD 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 696 - 981 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4LRME 3.526 Active DFGin‑BLAminus in-in in-in YUN Type1 697 - 983 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9U8CA 3.5 Inactive DFGin‑BLAminus in-out in-out A1L8T Type1 696 - 989 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9U8CB 3.5 Active DFGin‑BLAminus in-in in-in A1L8T Type1 696 - 986 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9U8CC 3.5 Inactive DFGin‑BLAminus in-out in-in A1L8T Type1 696 - 980 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9U8CD 3.5 None DFGin‑BLAminus in-in in-none A1L8T Type1 696 - 987 4 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JX0A 2.53 Active DFGin‑BLAminus in-in in-in YY3, YY3 Type1, Allosteric 701 - 989 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4G5JA 2.8 Active DFGin‑BLAminus in-in in-in 0WN, 0WM, 0WM Type1, Allosteric, Allosteric 696 - 1016 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8D76A 2.4 Active DFGin‑BLAminus in-in in-in QFO Type1.5_Back 703 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8D76B 2.4 Active DFGin‑BLAminus in-in in-in QFO Type1.5_Back 702 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus in-in in-none FZP Type1.5_Back 696 - 1019 5 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GL9A 2.147 Active DFGin‑BLAminus in-in in-in A1IMT Type1.5_Back 696 - 1019 4 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus in-in in-in A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GI9A 3.12 Active DFGin‑BLAminus in-in in-in A1ILZ Type1.5_Back 696 - 1018 7 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1ZA 2.4 Active DFGin‑BLAminus in-in in-in X9B Type1.5_Back 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus in-in in-in A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus in-in none-none 3QY Type1.5_Back 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus in-in in-none 4ZJ Type1.5_Back 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus in-in in-none 4ZQ Type1.5_Back 696 - 1019 13 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus in-in in-none 4ZR Type1.5_Back 696 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus in-in in-none 60D Type1.5_Back 696 - 1019 13 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus in-in in-none 63N Type1.5_Back 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out FI3 Type1.5_Back 697 - 1018 9 None L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9DF4A 1.78 Active DFGin‑BLAminus in-in in-in A1A4E Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus in-in in-in A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9FQSA 1.783 Active DFGin‑BLAminus in-in in-in A1IE0 Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus in-in in-in A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GL8A 1.632 Active DFGin‑BLAminus in-in in-in A1IMT Type1.5_Back 701 - 1021 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W2OA 2.35 Inactive DFGin‑BLAminus out-out in-in 03P Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W2PA 2.05 Inactive DFGin‑BLAminus out-out in-in W2P Type1.5_Front 698 - 1018 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W2QA 2.2 Inactive DFGin‑BLAminus out-out in-in HKI Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EDPA 2.9 Inactive DFGin‑BLAplus in-in none-none No_ligand No_ligand 697 - 1018 15 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5XGMA 2.952 Inactive DFGin‑BLAplus in-in none-out 85X Type1 696 - 1019 16 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JRJA 2.943 Inactive DFGin‑BLAplus in-out in-none C6O Type1 696 - 1018 15 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5Y25A 3.102 Inactive DFGin‑BLAplus in-in none-none 8LU Type1 698 - 1017 16 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EDRA 2.6 Inactive DFGin‑BLAplus in-in none-none 5N4 Type1 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EM5A 2.65 Inactive DFGin‑BLAplus in-in none-none 5Q2 Type1 697 - 1019 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus in-in in-none ANP Type1 696 - 1018 14 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus out-none none-out N7K Type1.5_Back 700 - 984 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none 5N3 Type1.5_Back 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out KY9 Type3 701 - 985 16 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out KY9 Type3 700 - 1019 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none 8BS Type1 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RJ6A 2.7 Inactive DFGin‑BLBminus in-in in-none 3R0 Type1 697 - 1018 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus in-in in-none 5Q3 Type1.5_Back 697 - 1019 14 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none KXY Type3 701 - 1021 10 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WXNA 1.76 Inactive DFGin‑BLBplus out-out none-out No_ligand No_ligand 699 - 1014 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7UKWA 2.6 Inactive DFGin‑BLBplus out-out out-out No_ligand No_ligand 702 - 1014 2 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7TVDA 2.96 Inactive DFGin‑BLBplus in-out none-out No_ligand No_ligand 698 - 1009 16 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5ZTOA 2.649 Inactive DFGin‑BLBplus in-in none-none 9JO Type1 697 - 1017 17 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1008 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 8 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1011 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 700 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5NA 2.4 Inactive DFGin‑BLBplus out-out out-out QP7 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5PA 2.3 Inactive DFGin‑BLBplus out-out out-out QP4 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1013 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus out-out out-none ANP Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1013 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus out-out none-none ANP Type1 702 - 1014 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus out-out out-none ANP Type1 701 - 1015 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus out-out none-none ANP Type1 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1005 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out VO7 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus out-out out-none ANP Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7KY0A 3.1 Inactive DFGin‑BLBplus out-out out-none XA4 Type1 701 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFYA 1.7 Inactive DFGin‑BLBplus out-out none-out N7Z Type1 699 - 982 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6JB 2.0 Inactive DFGin‑BLBplus out-out out-out R2E Type1 699 - 984 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ZYQA 2.1 Inactive DFGin‑BLBplus out-none out-out V58 Type1 700 - 984 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5FEEA 2.7 Inactive DFGin‑BLBplus in-in in-out 5X4 Type1 697 - 1018 5 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYA 3.14 Inactive DFGin‑BLBplus out-out out-none 816 Type1 700 - 1014 11 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYC 3.14 Inactive DFGin‑BLBplus out-out out-none 816 Type1 700 - 1013 15 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYF 3.14 Inactive DFGin‑BLBplus out-none out-out 816 Type1 700 - 1013 13 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus out-out out-out ANP Type1 698 - 1015 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus out-out out-none ANP Type1 699 - 1014 13 None I706Q Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1DB 2.4 Inactive DFGin‑BLBplus out-out out-out ANP, NQ1 Type1, Type3 702 - 1013 12 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1LA 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 701 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1LC 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 702 - 1005 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1LD 2.8 Inactive DFGin‑BLBplus out-out none-out ANP, 9LL Type1, Type3 702 - 1015 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus out-out out-none ANP, O57 Type1, Type3 699 - 1019 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus out-out out-none AMP, O57 Type1, Type3 698 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus out-out out-in AMP, O57 Type1, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus out-out out-none AMP, O57 Type1, Type3 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6XL4A 2.06 Inactive DFGin‑BLBplus out-out out-none Q6K, NQ1 Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6XL4D 2.06 Inactive DFGin‑BLBplus out-out out-none ANP, NQ1 Type1, Type3 700 - 1013 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none ANP, IXR Type1, Type3 702 - 1013 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none ANP, IXR Type1, Type3 702 - 1005 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5D41A 2.31 Inactive DFGin‑BLBplus out-out none-none ANP, 57N Type1, Type3 698 - 1014 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKA 2.2 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 701 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKB 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 699 - 1007 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKC 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 699 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKD 2.2 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKE 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 698 - 1007 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6DUKF 2.2 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 701 - 1009 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none 8BS, JBJ Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none 8BS, JBJ Type1, Type3 701 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKD 3.1 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none 8BS, JBJ Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none 8BS, JBJ Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXMB 2.192 Inactive DFGin‑BLBplus out-out none-none YY3, 9LL Type1, Type3 701 - 1012 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXMD 2.192 Inactive DFGin‑BLBplus out-out none-none ANP, 9LL Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPA 2.16 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPB 2.16 Inactive DFGin‑BLBplus out-out out-out ANP, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPD 2.16 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPF 2.16 Inactive DFGin‑BLBplus out-out out-none ANP, JBJ Type1, Type3 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 701 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none YY3, VNS Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LTXA 2.3 Inactive DFGin‑BLBplus out-out none-out ANP, YFA Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LTXB 2.3 Inactive DFGin‑BLBplus out-out out-none ANP, YFA Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LTXC 2.3 Inactive DFGin‑BLBplus out-out none-none ANP, YFA Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LTXD 2.3 Inactive DFGin‑BLBplus out-out out-none ANP, YFA Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1012 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 701 - 1011 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 700 - 1008 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6Z4BA 2.5 Inactive DFGin‑BLBplus out-none out-out Q6K, 9LL Type1, Type3 700 - 982 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6Z4BB 2.5 Inactive DFGin‑BLBplus out-out none-out Q6K, 9LL Type1, Type3 699 - 984 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out 8BS, 57N Type1, Type3 700 - 984 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none ANP, VNS Type1, Type3 700 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus out-out out-out 80U Type1.5_Back 697 - 985 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TOV Type1.5_Back 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus out-out none-out YA6 Type1.5_Back 701 - 1009 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus out-out out-none YAA Type1.5_Back 701 - 1005 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus out-out out-none N7K Type1.5_Back 700 - 982 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus out-none none-none N7Q Type1.5_Back 700 - 985 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus out-out none-none N7Q Type1.5_Back 698 - 984 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus out-out out-none N7W Type1.5_Back 700 - 982 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus out-out none-out N7W Type1.5_Back 700 - 984 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus out-out none-out N7Z Type1.5_Back 699 - 984 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus out-none none-none N7B Type1.5_Back 701 - 982 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus out-none out-none N7B Type1.5_Back 700 - 984 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus out-out none-none N78 Type1.5_Back 700 - 985 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus out-out out-none N78 Type1.5_Back 698 - 984 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus out-out none-out N82 Type1.5_Back 699 - 984 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus out-none none-out N82 Type1.5_Back 698 - 984 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out HKI Type1.5_Back 699 - 982 11 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 700 - 1014 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 701 - 1014 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus out-none out-out 816 Type1.5_Back 701 - 1014 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 699 - 1014 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus out-out out-out 816 Type1.5_Back 700 - 1016 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none W2R Type1.5_Back 698 - 1017 14 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus out-out out-none HYZ Type1.5_Back 702 - 1016 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus out-out out-none POX Type1.5_Back 702 - 1015 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus out-out out-out 26X Type1.5_Back 700 - 1014 8 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus out-out none-out ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 704 - 983 16 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus out-out none-none ITI Type1.5_Back 703 - 983 16 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus out-out out-none 03P Type1.5_Back 701 - 1017 7 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out W2R Type1.5_Back 701 - 1019 12 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus out-out out-in W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus out-out out-none W19 Type1.5_Back 701 - 1018 12 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus out-out out-out FMM Type1.5_Back 702 - 1018 8 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus out-out out-none 2EI Type1.5_Back 699 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus out-out out-none 26X Type1.5_Back 705 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus out-out out-none 26X Type1.5_Back 702 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus out-out out-none A1H7N Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus out-out out-out A1H7O Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus out-out out-none A1H7O Type1.5_Back 703 - 984 12 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus out-out out-out A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus out-out out-out A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus out-none out-out A1IUK Type1.5_Back 702 - 986 11 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus out-none out-out A1IUK Type1.5_Back 702 - 985 6 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WAKC 2.4 Inactive DFGin‑BLBplus out-out none-out TQA Type1.5_Front 701 - 1014 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WXNC 1.76 Inactive DFGin‑BLBplus out-out none-out UEJ Type1.5_Front 701 - 1014 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WXND 1.76 Inactive DFGin‑BLBplus out-out out-none UEJ Type1.5_Front 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out IXC Type1.5_Front 702 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type1.5_Front, Type1 702 - 1002 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out 9LL Type3 702 - 985 17 None T790M,C797S,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out KY9 Type3 702 - 990 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1DC 2.4 Inactive DFGin‑BLBplus out-out out-none NQ1, ANP Type3, Type1 702 - 1006 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1DD 2.4 Inactive DFGin‑BLBplus out-out out-none NQ1, ANP Type3, Type1 701 - 1008 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6XL4B 2.06 Inactive DFGin‑BLBplus out-out none-none NQ1, Q6K Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPC 2.16 Inactive DFGin‑BLBplus out-out none-none JBJ, YY3 Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXPE 2.16 Inactive DFGin‑BLBplus out-out none-none JBJ, YY3 Type3, Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out VNS, ANP Type3, Type1 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none VNS, ANP Type3, Type1 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 703 - 1004 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type3, Type1 702 - 1003 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out 57N, 7G9 Type3, Type1 700 - 984 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out 57N, 7G9 Type3, Type1 699 - 984 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1007 16 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1008 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out VNS, YY3 Type3, Type1 701 - 1007 15 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 703 - 1007 16 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6XL4C 2.06 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 700 - 1011 7 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7UKWD 2.6 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 702 - 1012 6 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV4B 2.2 Inactive DFGin‑BLBtrans out-out out-none No_ligand No_ligand 702 - 1007 3 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFDA 3.6 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 11 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFDB 3.6 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 8 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFEA 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 702 - 1002 8 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFEB 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1012 11 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFEC 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 702 - 983 11 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RFED 2.9 Inactive DFGin‑BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 11 None K823E Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6P1DA 2.4 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1021 13 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none QP1 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 700 - 1014 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1009 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5NB 2.4 Inactive DFGin‑BLBtrans out-out out-none QP7 Type1 700 - 1008 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5NC 2.4 Inactive DFGin‑BLBtrans out-out out-out QP7 Type1 701 - 1007 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5ND 2.4 Inactive DFGin‑BLBtrans out-out out-out QP7 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5PB 2.3 Inactive DFGin‑BLBtrans out-out out-out QP4 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5PC 2.3 Inactive DFGin‑BLBtrans out-out out-none QP4 Type1 701 - 1008 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6V5PD 2.3 Inactive DFGin‑BLBtrans out-out out-out QP4 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WAKB 2.4 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1020 4 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6WXNB 1.76 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7UKWB 2.6 Inactive DFGin‑BLBtrans out-out none-none ZRT Type1 702 - 1010 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7UKWC 2.6 Inactive DFGin‑BLBtrans out-out out-none ZRT Type1 700 - 1005 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1008 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8FV4A 2.2 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 701 - 1013 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1008 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8TO4A 2.99 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1021 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 699 - 1007 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 698 - 1022 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1013 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO Type1 700 - 1015 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2CA 2.05 Inactive DFGin‑BLBtrans out-out out-out 7XR Type1 700 - 1015 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2CB 2.05 Inactive DFGin‑BLBtrans out-out out-out 7XR Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2FA 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 700 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2FB 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 699 - 1010 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2FC 2.2 Inactive DFGin‑BLBtrans out-out out-none 7XU Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2FD 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 697 - 1014 7 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXIA 3.0 Inactive DFGin‑BLBtrans out-out none-none 8BS Type1 700 - 1006 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXID 3.0 Inactive DFGin‑BLBtrans out-out out-none 8BS Type1 702 - 1006 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXLA 2.4 Inactive DFGin‑BLBtrans out-out out-none VO7 Type1 701 - 1013 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXMA 2.192 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7KY0B 3.1 Inactive DFGin‑BLBtrans out-out out-out XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7KY0D 3.1 Inactive DFGin‑BLBtrans out-out out-none XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U98B 3.42 Inactive DFGin‑BLBtrans out-out out-out M1O Type1 701 - 1005 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U98C 3.42 Inactive DFGin‑BLBtrans out-out out-out M1O Type1 702 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U98D 3.42 Inactive DFGin‑BLBtrans out-out none-out M1O Type1 701 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1WA 3.2 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 701 - 1007 4 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1WB 3.2 Inactive DFGin‑BLBtrans out-out out-none R2E Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1WC 3.2 Inactive DFGin‑BLBtrans out-out out-none R2E Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8F1WD 3.2 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 700 - 1007 4 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6Z4DA 2.0 Inactive DFGin‑BLBtrans out-out out-out 8BS Type1 701 - 984 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6JA 2.0 Inactive DFGin‑BLBtrans out-out out-out R2E Type1 699 - 982 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6KA 2.0 Inactive DFGin‑BLBtrans out-out out-out R28 Type1 700 - 984 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6KB 2.0 Inactive DFGin‑BLBtrans out-none none-out R28 Type1 700 - 982 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6KC 2.0 Inactive DFGin‑BLBtrans out-none none-out R28 Type1 700 - 984 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7A6KD 2.0 Inactive DFGin‑BLBtrans out-out none-out R28 Type1 702 - 984 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I24A 1.8 Inactive DFGin‑BLBtrans out-out out-out 1C9 Type1 700 - 1014 13 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I24B 1.8 Inactive DFGin‑BLBtrans out-out out-out 1C9 Type1 700 - 1014 11 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5YU9A 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 700 - 1017 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5YU9B 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 699 - 1011 13 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5YU9C 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 697 - 1021 12 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5YU9D 1.95 Inactive DFGin‑BLBtrans out-out out-out 1E8 Type1 700 - 1012 13 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I22A 1.71 Inactive DFGin‑BLBtrans out-out out-out IRE Type1 700 - 1014 13 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO4B 1.621 Inactive DFGin‑BLBtrans out-out out-out ATP Type1 700 - 1014 13 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2GS7A 2.6 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 703 - 1012 4 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2GS7B 2.6 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1016 3 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3GT8A 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 700 - 1014 15 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3GT8B 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1007 15 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3GT8C 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 699 - 1007 13 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3GT8D 2.955 Inactive DFGin‑BLBtrans out-out out-none ANP Type1 701 - 1010 15 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CNOA 1.55 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 700 - 1015 11 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC6A 1.901 Inactive DFGin‑BLBtrans out-out out-none A1IZ9 Type1 698 - 1014 14 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC6B 1.901 Inactive DFGin‑BLBtrans out-out out-none A1IZ9 Type1 698 - 1014 14 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GDVA 2.218 Inactive DFGin‑BLBtrans out-none out-none Q6K Type1 702 - 985 15 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GDVB 2.218 Inactive DFGin‑BLBtrans out-none none-out Q6K Type1 702 - 985 17 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4HJOA 2.75 Inactive DFGin‑BLBtrans out-out out-out AQ4 Type1 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5CNNB 1.9 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 700 - 1014 11 None I706Q Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 6JXTA 2.307 Inactive DFGin‑BLBtrans out-out out-in YY3 Type1 697 - 984 2 None E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none 7XO, ANP Type1, Allosteric 700 - 1011 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO, ANP Type1, Type1 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans out-out out-none A1IZ8 Type1.5_Back 699 - 1012 14 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans out-out out-none A1IZ8 Type1.5_Back 699 - 1012 14 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8PO3A 2.13 Inactive DFGin‑BLBtrans out-out out-out 2II Type1.5_Front 706 - 1001 13 None V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8EMEA 3.32 Inactive DFGin‑None out-out none-none No_ligand No_ligand 700 - 1007 21 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3GOPA 2.8 Inactive DFGin‑None in-na none-none No_ligand No_ligand 676 - 1018 18 None K745M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7JXIB 3.0 Inactive DFGin‑None out-out none-none 8BS Type1 702 - 1004 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7KY0C 3.1 Inactive DFGin‑None out-out out-none XA4 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7U98A 3.42 Inactive DFGin‑None out-out out-none M1O Type1 701 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 7ZYQB 2.1 Inactive DFGin‑None out-out none-out V58 Type1 700 - 984 19 None T790M,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIWB 3.1 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIWD 3.1 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIXB 3.1 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIXD 3.1 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIYB 2.981 Inactive DFGin‑None in-in in-none ADP Type1 688 - 984 4 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4RIYD 2.981 Inactive DFGin‑None in-in in-in ADP Type1 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None out-out out-none HKI Type1.5_Back 700 - 984 14 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 8H7XB 3.404 Inactive DFGinter‑None in-in out-none No_ligand No_ligand 697 - 1018 7 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5XGNB 3.0 Inactive DFGinter‑None in-in out-out No_ligand No_ligand 697 - 1019 4 None T790M,C797S Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JITB 3.1 Inactive DFGinter‑None in-in out-in No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2JIUB 3.05 Inactive DFGinter‑None in-in in-in No_ligand No_ligand 695 - 1004 0 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4G5PB 3.17 Inactive DFGinter‑None in-in out-out No_ligand No_ligand 697 - 1018 8 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 3IKAB 2.9 Inactive DFGinter‑None in-in out-in No_ligand No_ligand 697 - 1017 2 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4WD5B 3.3 Inactive DFGinter‑None in-out out-out No_ligand No_ligand 697 - 1016 5 None T790M Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UWDA 3.06 Inactive DFGinter‑None out-out out-out 8OV Type1 702 - 984 12 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RF9A 3.5 Inactive DFGout‑BBAminus out-none in-out No_ligand No_ligand 699 - 983 2 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZJVA 2.7 Inactive DFGout‑BBAminus out-out in-in No_ligand No_ligand 703 - 985 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4ZJVB 2.7 Inactive DFGout‑BBAminus out-out in-in No_ligand No_ligand 703 - 982 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HG5A 1.52 Inactive DFGout‑BBAminus out-out in-in 633 Type1 700 - 1001 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HG7A 1.85 Inactive DFGout‑BBAminus out-out in-in 630 Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HG8A 1.42 Inactive DFGout‑BBAminus out-out in-in 634 Type1 700 - 999 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5HG9A 2.15 Inactive DFGout‑BBAminus out-out in-in 63A Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5U8LA 1.6 Inactive DFGout‑BBAminus out-out in-in O44 Type1 702 - 990 0 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UG8A 1.46 Inactive DFGout‑BBAminus out-out in-in 8BP Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UGAA 1.82 Inactive DFGout‑BBAminus out-out in-in 8BM Type1 703 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I1ZA 3.0 Inactive DFGout‑None out-out in-in No_ligand No_ligand 701 - 987 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I21A 3.37 Inactive DFGout‑None out-out in-in No_ligand No_ligand 703 - 1019 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I21B 3.37 Inactive DFGout‑None out-out in-in No_ligand No_ligand 703 - 1020 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 2RF9B 3.5 Inactive DFGout‑None out-none in-out No_ligand No_ligand 701 - 985 6 None None Epidermal growth factor receptor Homo sapiens
EGFR_HUMAN 4I20A 3.34 Inactive DFGout‑None out-out in-in No_ligand No_ligand 701 - 987 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens

TYR_EGFR (Epidermal growth factor receptor)

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative

Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism