TYR_MERTK (Tyrosine-protein kinase Mer)

Total number of chains: 67
Active chains: 2
Uniprot: MERTK_HUMAN
Kinase Domain Residues: 587 - 856
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 22 32.8% 5U6CA
DFGin BLBplus 18 26.9% 7AVXA
DFGout None 7 10.4% 7AVXB
DFGin BLAminus 6 9.0% AF-Q12866-K1A
DFGout BBAminus 6 9.0% 7AAYA
DFGin BLBminus 5 7.5% 7AVYA
None None 2 3.0% 7OAMA
DFGin BLAplus 1 1.5% 7M5ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q12866-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer
AF-Q12866-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer
7AAZA 1.855 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai R6K Type1.5_Front 574 - 863 0 None None Tyrosine-protein kinase Mer
9BHIA 2.07 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APF Type1.5_Front 578 - 864 0 None None Tyrosine-protein kinase Mer
9BHJA 2.294 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APG Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer
9BHKA 2.106 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APH Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer
7M5ZB 3.06 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 574 - 862 0 None None Tyrosine-protein kinase Mer
7AVYA 2.31 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4E Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
7AW2A 2.1 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4W Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7OLSA 1.89 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VJZ Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7OLVA 2.13 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK2 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7OLXA 1.98 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK5 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer
7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
7DXLA 3.146 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nnoai APEdist_aaao E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
7DXLB 3.146 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
3BPRA 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
3BPRB 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
3BPRC 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
3BPRD 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
4M3QB 2.718 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
4MHAA 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 580 - 863 0 None None Tyrosine-protein kinase Mer
5K0KA 2.545 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
5K0XA 2.231 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
6MEPA 2.893 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer
7AVXA 2.44 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai S4K Type1.5_Front 577 - 862 0 None None Tyrosine-protein kinase Mer
5TD2B 2.68 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 577 - 861 0 None None Tyrosine-protein kinase Mer
4MH7B 2.51 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 577 - 862 0 None None Tyrosine-protein kinase Mer
5TC0B 2.24 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 578 - 861 0 None None Tyrosine-protein kinase Mer
7AB0A 1.74 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
5TD2A 2.68 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 7AE Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
7OAMB 2.65 Inactive DFGin‑None none-none none-out TYR APEdihe_nniai APEdist_aaao V6H Type1 576 - 862 0 None None Tyrosine-protein kinase Mer
3TCPA 2.69 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan CKJ Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
3TCPB 2.69 Inactive DFGin‑None out-none none-out TYR APEdihe_nniai APEdist_aaao CKJ Type1 576 - 861 0 None None Tyrosine-protein kinase Mer
4M3QA 2.718 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
4MH7A 2.51 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan MH7 Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
4MHAB 2.59 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
5K0KB 2.545 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
5TC0A 2.24 Inactive DFGin‑None none-none none-none TYR APEdihe_nniai APEdist_aaai 79Y Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
5U6CA 2.1 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 572 - 864 0 None None Tyrosine-protein kinase Mer
5U6CB 2.1 Inactive DFGin‑None out-out none-out TYR APEdihe_nniai APEdist_aaao 7YS Type1 575 - 862 0 None None Tyrosine-protein kinase Mer
7AB1A 1.93 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan C6F Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AB2A 1.78 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan R6N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AVZA 2.04 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AW0A 1.893 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4Q Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AW3A 1.99 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4Z Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7M5ZA 3.06 Inactive DFGin‑None in-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
6MEPB 2.893 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 578 - 862 0 None None Tyrosine-protein kinase Mer
9KS9B 2.8 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
7XHYA 2.16 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan E0X Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer
9KRYB 2.25 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer
7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer
7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer
7AVXB 2.44 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4K Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
9KRZA 2.6 Inactive DFGout‑None out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6K Type1.5_Front 577 - 864 0 None None Tyrosine-protein kinase Mer
9KRZB 2.6 Inactive DFGout‑None out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6K Type1.5_Front 575 - 863 0 None None Tyrosine-protein kinase Mer
9KRYA 2.25 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer
9KS9A 2.8 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type2 576 - 862 0 None None Tyrosine-protein kinase Mer
7AAXA 1.762 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan R6H Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7AW1A 1.98 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4T Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
7OAMA 2.65 Inactive None‑None out-none none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 575 - 863 0 None None Tyrosine-protein kinase Mer
5K0XB 2.231 Inactive None‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 575 - 863 0 None None Tyrosine-protein kinase Mer

TYR_MERTK (Tyrosine-protein kinase Mer)

Total number of chains: 67
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 22 32.8% 5U6CA
DFGin BLBplus 18 26.9% 7AVXA
DFGout None 7 10.4% 7AVXB
DFGin BLAminus 6 9.0% AF-Q12866-K1A
DFGout BBAminus 6 9.0% 7AAYA
DFGin BLBminus 5 7.5% 7AVYA
None None 2 3.0% 7OAMA
DFGin BLAplus 1 1.5% 7M5ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MERTK_HUMAN AF-Q12866-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN AF-Q12866-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AAZA 1.855 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai R6K Type1.5_Front 574 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9BHIA 2.07 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APF Type1.5_Front 578 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9BHJA 2.294 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APG Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9BHKA 2.106 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_oiiai APEdist_aaai A1APH Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7M5ZB 3.06 Inactive DFGin‑BLAplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 574 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AVYA 2.31 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4E Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW2A 2.1 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4W Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7OLSA 1.89 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VJZ Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7OLVA 2.13 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK2 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7OLXA 1.98 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK5 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus out-none none-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7DXLA 3.146 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nnoai APEdist_aaao E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7DXLB 3.146 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BPRA 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BPRB 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BPRC 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3BPRD 2.8 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4M3QB 2.718 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 577 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4MHAA 2.59 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 580 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5K0KA 2.545 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5K0XA 2.231 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AVXA 2.44 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai S4K Type1.5_Front 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5TD2B 2.68 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 577 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4MH7B 2.51 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5TC0B 2.24 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AB0A 1.74 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5TD2A 2.68 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 7AE Type1 577 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7OAMB 2.65 Inactive DFGin‑None none-none none-out TYR APEdihe_nniai APEdist_aaao V6H Type1 576 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3TCPA 2.69 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan CKJ Type1 577 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 3TCPB 2.69 Inactive DFGin‑None out-none none-out TYR APEdihe_nniai APEdist_aaao CKJ Type1 576 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4M3QA 2.718 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 24K Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4MH7A 2.51 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan MH7 Type1 577 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 4MHAB 2.59 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan 4MH Type1 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5K0KB 2.545 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 6Q1 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5TC0A 2.24 Inactive DFGin‑None none-none none-none TYR APEdihe_nniai APEdist_aaai 79Y Type1 578 - 861 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5U6CA 2.1 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 7YS Type1 572 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5U6CB 2.1 Inactive DFGin‑None out-out none-out TYR APEdihe_nniai APEdist_aaao 7YS Type1 575 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AB1A 1.93 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan C6F Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AB2A 1.78 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan R6N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AVZA 2.04 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW0A 1.893 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4Q Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW3A 1.99 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4Z Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7M5ZA 3.06 Inactive DFGin‑None in-out none-none TYR APEdihe_nnnai APEdist_aaan YR7 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 6MEPB 2.893 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan 9VS Type1.5_Back 578 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KS9B 2.8 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type1 577 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7XHYA 2.16 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan E0X Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KRYB 2.25 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AVXB 2.44 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4K Type1 577 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KRZA 2.6 Inactive DFGout‑None out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6K Type1.5_Front 577 - 864 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KRZB 2.6 Inactive DFGout‑None out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6K Type1.5_Front 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KRYA 2.25 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 9KS9A 2.8 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type2 576 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AAXA 1.762 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan R6H Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7AW1A 1.98 Inactive DFGout‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan S4T Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 7OAMA 2.65 Inactive None‑None out-none none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
MERTK_HUMAN 5K0XB 2.231 Inactive None‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan K0X Type1 575 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens

TYR_MERTK (Tyrosine-protein kinase Mer)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism