CMGC_DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

Total number of chains: 233
Active chains: 145
Family: CMGC
Uniprot: DYR1A_HUMAN
Kinase Domain Residues: 159 - 479
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 225 96.6% AF-Q13627-K1A
DFGin None 6 2.6% 6UIPA
DFGin ABAminus 2 0.9% 6UIPB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
AF-Q13627-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 151 - 487 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
AF-Q13627-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 151 - 487 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6T6AD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6LN1A 2.699 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EKU Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6LN1B 2.699 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EKU Type1 140 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4RA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QY8 Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4RB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QY8 Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A52B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYB Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJMA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKW Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJMB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKW Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJSA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKH Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJSB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKH Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4SA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYE Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4ZA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6SD Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A51A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A53A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A53B 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5DA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYW Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5LA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QZW Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5NA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R05 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5NB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R05 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJ2A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ5 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJ4A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHZ Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJ5A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHW Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJ7A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHT Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJ8A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJAA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJWA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKQ Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKLA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RK5 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6A1FA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OF Type1 134 - 483 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6A1GA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OL Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6A1GB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OL Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8YEVA 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8YEVB 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ1A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ1B 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ1C 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ1D 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ2A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ2B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ2C 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLJA 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLJB 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLJC 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLJD 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLKA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E2 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YLLA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E3 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YU2A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YU2B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YU2C 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4YU2D 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6QU2A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6QU2B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6QU2C 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6QU2D 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S11A 2.445 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQE Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S14A 1.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S17A 1.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQK Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1BA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KRQ Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1HA 1.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQZ Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1IA 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1IB 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1IC 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1ID 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S1JA 1.408 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KRK Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6T6AA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6T6AB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6T6AC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UWYA 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UWYB 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UWYC 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UWYD 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8R8EB 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8R8EC 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8R8ED 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 135 - 480 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHSB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4VZ Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8T2HA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIR Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8T2HB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIR Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9CY5A 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A04 Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9CY5B 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A04 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4EA 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4EB 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4ED 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4LA 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZC3 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4LD 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZC3 Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4QB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y3L Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4QD 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y3L Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4TA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4TB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4TD 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A54A 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A54B 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A54D 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIFA 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5T Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIJB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIJD 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EILA 2.465 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6B Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIPD 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIQD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6Z Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EISB 2.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6N Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EISD 2.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6N Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EJ4C 2.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7W Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6YF8A 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6YF8B 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6YF8D 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NA 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NB 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NC 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5ND 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NE 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NF 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NG 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 137 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3RA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R7O Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3RB 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R7O Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3GA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3GB 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3GC 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3GD 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FPXA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CC9 Type1 136 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FPXB 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CC9 Type1 143 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2VX3A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2VX3B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2VX3C 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2VX3D 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2WO6A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
2WO6B 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4AZEA 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 132 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4AZEB 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 135 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4AZEC 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 132 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5AIKA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5AIKB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5AIKC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5AIKD 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYH Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A55A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QZ2 Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5BA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MFR Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7ZH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7ZH8B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7ZH8C 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7ZH8D 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3QA 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8C3QB 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UIPB 3.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 136 - 478 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UIPC 3.7 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni Q8J Type1 131 - 477 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4OB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EILC 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A52A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QYB Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7OY6C 2.38 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi 39I Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJVA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJVB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJYA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AJYB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AK2A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RHH Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AK2B 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RHH Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKAA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKAB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKBA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RJZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKBB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RJZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7AKEB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4MQ2D 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
8R8EA 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii YOX Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHSA 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4VZ Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHSC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4VZ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHSD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4VZ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHTA 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4WD Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHTB 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHTC 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7FHTD 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANQA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANQB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi EHB Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANQC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANQD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 136 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HRM Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANRC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
3ANRD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4NCTA 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4NCTB 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4NCTC 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 479 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
4NCTD 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A3XA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi QIV Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A3XB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi QIV Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A3XC 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi QIV Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A3XD 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi QIV Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4EC 2.68 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 7QQ Type1 134 - 473 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4LB 2.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi ZC3 Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4LC 2.73 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iioi ZC3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4QA 2.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi Y3L Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4QC 2.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi Y3L Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A4TC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi AJG Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
5A54C 2.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 5PW Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIFB 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B5T Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIFC 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B5T Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIFD 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B5T Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIJA 2.42 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EILB 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6B Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EILD 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6B Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIPA 2.56 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIPC 2.56 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B7B Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIQA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Z Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIQB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Z Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIQC 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Z Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIRA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6H Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIRB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6H Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIRC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6H Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIRD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii B6H Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EISA 2.36 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6N Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EISC 2.36 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6N Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIVA 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Q Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIVB 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Q Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIVC 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B6Q Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIVD 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Q Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EJ4A 2.88 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi B7W Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EJ4B 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B7W Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EJ4D 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii B7W Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6YF8C 3.198 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OPW Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A4WB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii QYH Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A55B 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii QZ2 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7A5BB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii MFR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7O7KA 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6ZV, LI Type1, Allosteric 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7O7KB 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi 6ZV, LI Type1, Allosteric 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6EIJC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B5Z Type1.5_Front 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6UIPA 3.7 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 131 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FT2A 2.9 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE6 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FT3A 2.7 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE7 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FT4A 3.0 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IFJ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FT6A 3.0 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE8 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
9FUFA 2.7 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IFO Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
6S11B 2.445 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii KQE Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
7Z5NH 2.77 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_niii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A

CMGC_DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

Total number of chains: 235
Active chains: 145
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 226 96.2% AF-Q13627-K1A
DFGin None 6 2.6% 6UIPA
DFGin ABAminus 3 1.3% 9KRJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DYR1A_HUMAN 7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN AF-Q13627-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 151 - 487 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN AF-Q13627-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 151 - 487 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6T6AD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6LN1A 2.699 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EKU Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6LN1B 2.699 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EKU Type1 140 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4RA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QY8 Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4RB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QY8 Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A52B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYB Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJMA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKW Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJMB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKW Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJSA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKH Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJSB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKH Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4SA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYE Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4ZA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6SD Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A51A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A53A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A53B 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5DA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYW Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5LA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QZW Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5NA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R05 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5NB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R05 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJ2A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ5 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJ4A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHZ Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJ5A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHW Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJ7A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RHT Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJ8A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJAA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RJ2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJWA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RKQ Type1 149 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKLA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RK5 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6A1FA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OF Type1 134 - 483 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6A1GA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OL Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6A1GB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 9OL Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8YEVA 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8YEVB 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ1A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ1B 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ1C 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ1D 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ2A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ2B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ2C 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLJA 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLJB 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLJC 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLJD 2.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E1 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLKA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E2 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YLLA 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4E3 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YU2A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YU2B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YU2C 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4YU2D 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4H5 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6QU2A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6QU2B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6QU2C 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6QU2D 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JHW Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S11A 2.445 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQE Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S14A 1.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S17A 1.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQK Type1 134 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1BA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KRQ Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1HA 1.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KQZ Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1IA 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1IB 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1IC 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1ID 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KR8 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S1JA 1.408 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KRK Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6T6AA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6T6AB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6T6AC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MLW Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UWYA 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UWYB 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UWYC 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UWYD 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QKG Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8R8EB 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8R8EC 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8R8ED 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YOX Type1 135 - 480 0 None None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHSB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4VZ Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8T2HA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIR Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8T2HB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIR Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9CY5A 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A04 Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9CY5B 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A04 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4EA 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4EB 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4ED 2.68 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7QQ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4LA 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZC3 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4LD 2.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZC3 Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4QB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y3L Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4QD 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y3L Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4TA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4TB 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4TD 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AJG Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A54A 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A54B 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A54D 2.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5PW Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIFA 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5T Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIJB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIJD 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EILA 2.465 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6B Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIPD 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIQD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6Z Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EISB 2.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6N Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EISD 2.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B6N Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EJ4C 2.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B7W Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6YF8A 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6YF8B 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6YF8D 3.198 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OPW Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NA 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NB 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NC 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5ND 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NE 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NF 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NG 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 137 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3RA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R7O Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3RB 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii R7O Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3GA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3GB 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3GC 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3GD 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QS0 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FPXA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CC9 Type1 136 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FPXB 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CC9 Type1 143 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2VX3A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2VX3B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2VX3C 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2VX3D 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2WO6A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 2WO6B 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D15 Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4AZEA 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 132 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4AZEB 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 135 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4AZEC 3.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RA Type1 132 - 481 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5AIKA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5AIKB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5AIKC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5AIKD 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AWR Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QYH Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A55A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QZ2 Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5BA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MFR Type1 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7ZH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 482 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7ZH8B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7ZH8C 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7ZH8D 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IWU, IWU Type1, Allosteric 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3QA 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8C3QB 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UIPB 3.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 136 - 478 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UIPC 3.7 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni Q8J Type1 131 - 477 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4OB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EILC 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A52A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii QYB Type1 148 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7OY6C 2.38 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi 39I Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJVA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJVB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKK Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJYA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AJYB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RKZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AK2A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RHH Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AK2B 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RHH Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKAA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKAB 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK2 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKBA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RJZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKBB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RJZ Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKEA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7AKEB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RK8 Type1 148 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4MQ2D 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 2C4 Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 8R8EA 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii YOX Type1 135 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHSA 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4VZ Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHSC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4VZ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHSD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4VZ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHTA 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4WD Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHTB 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHTC 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7FHTD 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 4WD Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANQA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANQB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi EHB Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANQC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANQD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi EHB Type1 136 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HRM Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANRC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 3ANRD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4NCTA 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4NCTB 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4NCTC 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 479 0 SEP301,PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 4NCTD 2.597 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 2K2 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A3XA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi QIV Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A3XB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi QIV Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A3XC 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi QIV Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A3XD 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi QIV Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4EC 2.68 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 7QQ Type1 134 - 473 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4LB 2.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi ZC3 Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4LC 2.73 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iioi ZC3 Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4QA 2.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi Y3L Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4QC 2.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi Y3L Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A4TC 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi AJG Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 5A54C 2.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 5PW Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIFB 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B5T Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIFC 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B5T Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIFD 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B5T Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIJA 2.42 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B5Z Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EILB 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6B Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EILD 2.465 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6B Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIPA 2.56 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii B7B Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIPC 2.56 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B7B Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIQA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Z Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIQB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Z Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIQC 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Z Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIRA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6H Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIRB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6H Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIRC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6H Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIRD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii B6H Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EISA 2.36 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6N Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EISC 2.36 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6N Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIVA 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Q Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIVB 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi B6Q Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIVC 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioi B6Q Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIVD 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B6Q Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EJ4A 2.88 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi B7W Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EJ4B 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B7W Type1 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EJ4D 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii B7W Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6YF8C 3.198 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OPW Type1 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A4WB 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii QYH Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A55B 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii QZ2 Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7A5BB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii MFR Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7O7KA 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6ZV, LI Type1, Allosteric 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7O7KB 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi 6ZV, LI Type1, Allosteric 133 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6EIJC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi B5Z Type1.5_Front 135 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6UIPA 3.7 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8J Type1 131 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FT2A 2.9 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE6 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FT3A 2.7 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE7 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FT4A 3.0 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IFJ Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FT6A 3.0 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IE8 Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 9FUFA 2.7 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iiii A1IFO Type1 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 6S11B 2.445 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_niii KQE Type1 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_HUMAN 7Z5NH 2.77 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_niii 3NG Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
DYR1A_MOUSE 9KRJA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus
DYR1A_MOUSE 9KRJB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus

CMGC_DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

Total number of chains: 2
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 9KRJA
DFGin BLAminus 1 50.0% 9KRJB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DYR1A_MOUSE 9KRJA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus
DYR1A_MOUSE 9KRJB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Mus musculus