Ligand

Protein kinases in complex with ANP

Total number of genes: 76

Total number of chains: 378

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	150	8QCGA
DFGin	BLAplus	5	2OZOA
DFGin	ABAminus	16	8R5EA
DFGin	BLBminus	5	4LGDA
DFGin	BLBplus	133	2SRCA
DFGin	BLBtrans	31	5X2AB
DFGin	None	22	6BXIA
DFGinter	None	10	7OPOG
DFGout	None	2	6VPHA
None	None	4	7F2XA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
AGC	AKT1	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	4EKKA	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	AKT1	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	4EKKB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	AKT2	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	1O6KA	1.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	AKT2	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	1O6LA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	GRK5	GRK5_HUMAN	G protein-coupled receptor kinase 5	4TNDA	1.802	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	GRK6	GRK6_HUMAN	G protein-coupled receptor kinase 6	2ACXA	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	GRK6	GRK6_HUMAN	G protein-coupled receptor kinase 6	2ACXB	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKCI	KPCI_HUMAN	Protein kinase C iota type	8R3YI	3.68	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
AGC	PRKCI	KPCI_HUMAN	Protein kinase C iota type	5LI1A	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2A	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2B	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2C	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2D	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	7LV3A	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	7LV3B	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2V55A	3.705	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2V55C	3.705	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
AGC	RPS6KA1	KS6A1_HUMAN	Ribosomal protein S6 kinase alpha-1	8XOVA	2.55	Inactive	DFGin	BLAplus	out-out	out-out	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOA	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOE	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOI	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOK	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOC	2.75	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOG	2.75	Inactive	DFGinter	None	out-out	out-none	ANP	Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G77A	2.499	Inactive	DFGin	None	none-none	out-in	ANP ANP	Allosteric Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G77B	2.499	Inactive	DFGin	None	none-none	out-in	ANP ANP	Allosteric Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G76B	3.0	Inactive	DFGinter	None	none-none	out-none	ANP	Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G78A	2.5	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G78B	2.5	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G76A	3.0	Inactive	DFGinter	None	none-none	out-in	ANP ANP	Type1 Allosteric
AGC	SGK1	SGK1_HUMAN	Serine/threonine-protein kinase Sgk1	2R5TA	1.9	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
AGC	STK38	STK38_HUMAN	Serine/threonine-protein kinase 38	6BXIA	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
AGC	STK38	STK38_HUMAN	Serine/threonine-protein kinase 38	6BXIB	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	2DWBA	2.5	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPGA	2.64	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPIA	2.0	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPLA	1.86	Inactive	DFGin	BLAminus	out-out	in-out	ANP R7D	Type1 Allosteric
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPLB	1.86	Inactive	DFGin	BLAminus	out-out	in-out	ANP R7D	Type1 Allosteric
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	2C6DA	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPJA	2.1	Inactive	DFGout	None	out-out	out-out	ANP	Type1
CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPHA	2.14	Inactive	DFGout	None	out-out	out-out	ANP	Type1
CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFRA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFSA	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFUA	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	CHEK1	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	5OOPA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1IG1A	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1JKKA	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1JKLA	1.62	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3EHAA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3F5UA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3DFCB	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3GU4A	1.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3GU5A	1.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	MELK	MELK_HUMAN	Maternal embryonic leucine zipper kinase	4BL1A	2.6	Inactive	DFGin	ABAminus	in-in	in-none	ANP	Type1
CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	1YXTA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	1XR1A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	3A99A	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	2BZKB	2.45	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	PLK1	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	8X72A	2.2	Inactive	DFGin	BLAminus	out-in	in-out	ANP	Type1
CAMK	PLK1	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	2OU7A	2.4	Inactive	DFGin	BLAminus	out-in	in-out	ANP	Type1
CAMK	PLK4	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	3COKA	2.25	None	DFGin	BLAminus	in-out	in-none	ANP	Type1
CAMK	PLK4	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	3COKB	2.25	None	DFGin	BLAminus	in-out	in-none	ANP	Type1
CAMK	RPS6KA5	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	3KN5A	2.4	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
CAMK	RPS6KA5	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	3KN5B	2.4	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
CAMK	STK11	STK11_HUMAN	Serine/threonine-protein kinase STK11	2WTKC	2.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CAMK	STK11	STK11_HUMAN	Serine/threonine-protein kinase STK11	2WTKF	2.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9A	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9B	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9C	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9D	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	4CXAA	3.15	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R99A	1.81	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BA	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BB	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BC	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BD	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
CMGC	CDK9	CDK9_HUMAN	Cyclin-dependent kinase 9	3MIAA	3.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3JUHA	1.66	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3JUHB	1.66	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3NSZA	1.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	1PJKA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	2PVRA	1.605	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3WOWA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	1JWHA	3.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3U87A	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3U87B	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	CSNK2A2	CSK22_HUMAN	Casein kinase II subunit alpha'	8QCGA	1.04	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
CMGC	CSNK2A2	CSK22_HUMAN	Casein kinase II subunit alpha'	8QCGB	1.04	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	DYRK1A	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	7A4OA	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	DYRK1A	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	7A4OB	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1J1BA	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1J1BB	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	8XN6A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	8XN6B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1PYXA	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1PYXB	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT3A	1.8	Inactive	DFGin	BLAminus	in-out	in-out	D7O ANP	Allosteric Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3QA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	6OPGA	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	2Y9QA	1.55	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4FMQA	2.098	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4NIFB	2.15	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4NIFE	2.15	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PSRA	1.85	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	3TEIA	2.404	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3PA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3PD	2.3	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT0A	1.65	Inactive	DFGin	BLAminus	in-in	in-out	ANP EAI	Type1 Allosteric
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT1A	1.8	Inactive	DFGin	BLAminus	in-in	in-out	ANP E2A	Type1 Allosteric
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT5A	1.95	Inactive	DFGin	BLAminus	in-in	in-out	ANP D5R	Type1 Allosteric
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8R5FA	1.65	Inactive	DFGin	BLAminus	in-in	in-out	ANP Y3H	Type1 Allosteric
CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	4Z9LA	2.1	Inactive	DFGin	ABAminus	out-out	none-out	ANP 880	Allosteric Type1
CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	8WGFA	1.85	Inactive	DFGin	ABAminus	in-out	out-out	ANP	Type1
CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	1JNKA	2.3	Inactive	DFGin	ABAminus	in-out	none-out	ANP	Type1
CMGC	MAPK12	MK12_HUMAN	Mitogen-activated protein kinase 12	1CM8A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK12	MK12_HUMAN	Mitogen-activated protein kinase 12	1CM8B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK7	MK07_HUMAN	Mitogen-activated protein kinase 7	4IC7A	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK7	MK07_HUMAN	Mitogen-activated protein kinase 7	4IC7D	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	6ZR5A	2.699	Inactive	DFGin	ABAminus	out-out	out-none	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	6ZR5B	2.699	Inactive	DFGin	ABAminus	out-out	out-out	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	2XRWA	1.33	Inactive	DFGin	ABAminus	in-out	none-none	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	2XS0A	2.6	Inactive	DFGin	ABAminus	in-out	none-none	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9A	2.34	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9C	2.34	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9D	2.34	Inactive	DFGin	ABAminus	in-in	in-out	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	8R5EA	1.7	Inactive	DFGin	ABAminus	in-out	out-out	ANP Y6K	Type1 Allosteric
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4QTDA	1.5	Inactive	DFGin	ABAminus	in-out	out-out	38Z ANP	Type1 Allosteric
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	9FT9A	2.35	Inactive	DFGin	BLAminus	in-out	in-out	ANP	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9B	2.34	Inactive	DFGin	None	in-in	in-in	ANP	Type1
CMGC	PRP4K	PRP4K_HUMAN	Serine/threonine-protein kinase PRP4 homolog	4IIRA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	PRP4K	PRP4K_HUMAN	Serine/threonine-protein kinase PRP4 homolog	4IIRB	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
CMGC	SRPK1	SRPK1_HUMAN	SRSF protein kinase 1	3BEGA	2.9	None	DFGin	BLAminus	in-none	in-in	ANP	Type1
OTHER	EIF2AK2	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	2A19B	2.5	Inactive	DFGin	ABAminus	in-in	in-out	ANP	Type1
OTHER	EIF2AK2	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	2A19C	2.5	Inactive	DFGin	ABAminus	in-in	none-none	ANP	Type1
OTHER	TP53RK	PRPK_HUMAN	EKC/KEOPS complex subunit TP53RK	6WQXC	2.53	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1
OTHER	TP53RK	PRPK_HUMAN	EKC/KEOPS complex subunit TP53RK	6WQXD	2.53	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WDYA	2.458	None	DFGin	BLAminus	out-none	in-none	ANP A6S	Type1 Type3
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WDYB	2.458	None	DFGin	BLAminus	out-none	in-none	ANP A6S	Type1 Type3
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WE8A	2.006	Inactive	DFGin	BLAminus	out-none	in-out	ANP A7Y	Type1 Type3
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WE8B	2.006	Inactive	DFGin	BLAminus	out-none	in-out	ANP A7Y	Type1 Type3
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5TF9A	2.5	Inactive	DFGin	BLAminus	out-none	in-out	7AV ANP	Type3 Type1
OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5TF9B	2.5	Inactive	DFGin	BLAminus	out-none	in-out	7AV ANP	Type3 Type1
OTHER	WNK3	WNK3_HUMAN	Serine/threonine-protein kinase WNK3	5O26A	2.379	Active	DFGin	BLAminus	out-none	in-in	ANP	Type1
OTHER	WNK3	WNK3_HUMAN	Serine/threonine-protein kinase WNK3	5O26B	2.379	Active	DFGin	BLAminus	out-none	in-in	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3C	2.9	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	6V2WB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXHA	2.81	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXHB	2.81	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXMA	2.42	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXXA	2.07	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXXC	2.07	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AYAB	2.59	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AYAD	2.59	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AY7B	2.41	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3SLSA	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP 77D	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3SLSB	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP 77D	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B3MA	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP SU5	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B3MB	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP SU5	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B7RA	1.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP T1K	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B7RB	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T1K	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B94A	2.0	Inactive	DFGin	BLBplus	out-out	out-out	ANP T3W	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B94B	2.0	Inactive	DFGin	BLBplus	out-out	out-none	ANP T3W	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B9LA	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T4N	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B9LB	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T4N	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3ORNA	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3OR	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3WIGA	2.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U80A	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EX	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4LMNA	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7UMBC	3.231	Inactive	DFGin	BLBplus	out-out	out-out	ANP U9F	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	6PP9B	2.59	Inactive	DFGin	BLBplus	out-out	out-out	ANP LCJ	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0VB	3.16	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0WB	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOA	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0XB	2.47	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0YB	3.45	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0ZB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U7ZA	2.805	Inactive	DFGin	BLBplus	out-out	out-out	3EW ANP	Type3 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U81A	2.701	Inactive	DFGin	BLBplus	out-out	out-out	3EY ANP	Type3 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXYB	3.6	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type3 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0TB	3.19	Inactive	DFGin	BLBplus	out-out	out-out	3EW ANP	Type3 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0UB	3.09	Inactive	DFGin	BLBplus	out-out	out-out	QO7 ANP	Type3 Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3B	2.9	Inactive	DFGin	None	out-out	out-out	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3D	2.9	Inactive	DFGin	None	out-out	out-out	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3A	2.9	Inactive	DFGinter	None	out-out	none-none	ANP	Type1
STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7F2XA	2.007	Inactive	None	None	out-out	out-out	ANP	Type1
STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNA	2.3	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNB	2.3	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALOA	2.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNC	2.3	Inactive	None	None	none-none	none-none	ANP	Type1
STE	MAP4K1	M4K1_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 1	6CQDA	2.12	Inactive	DFGin	BLAminus	in-in	out-out	ANP	Type1
STE	MAP4K1	M4K1_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 1	6CQDB	2.12	Inactive	DFGin	BLAminus	in-in	out-out	ANP	Type1
STE	MAP4K4	M4K4_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 4	4U40A	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKA	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKB	2.25	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKC	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKD	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIB	2.15	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIC	2.15	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWID	2.15	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIA	2.15	Inactive	DFGin	None	none-none	out-out	ANP	Type1
STE	PAK1	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	3Q4ZA	1.887	None	DFGin	BLAminus	out-none	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIFA	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIFB	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIGA	3.01	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4JDIA	1.85	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	5UPKB	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIEA	3.11	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIEB	3.11	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	7S46A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	7S47A	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIGB	3.01	Inactive	DFGin	None	in-in	in-in	ANP	Type1
STE	STK24	STK24_HUMAN	Serine/threonine-protein kinase 24	4QMLA	1.882	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	6AO5A	2.955	Inactive	DFGin	BLAplus	out-out	none-out	ANP	Type1
STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDA	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDB	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDC	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDD	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
STE	STRADA	STRAA_HUMAN	STE20-related kinase adapter protein alpha	2WTKB	2.65	None	DFGin	BLAminus	out-none	in-out	ANP	Type1
STE	STRADA	STRAA_HUMAN	STE20-related kinase adapter protein alpha	2WTKE	2.65	None	DFGin	BLAminus	in-none	in-out	ANP	Type1
STE	TNIK	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	7XZRB	2.26	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
STE	TNIK	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	7XZRA	2.26	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1.5_Front
TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	6UNQA	2.4	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	6UNRA	2.2	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TKL	ARAF	ARAF_HUMAN	Serine/threonine-protein kinase A-Raf	9AXMB	2.42	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	9AXXB	2.07	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	9AXYA	3.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6PP9A	2.59	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V2WA	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0TA	3.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0UA	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0VA	3.16	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0WA	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0XA	2.47	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0YA	3.45	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0ZA	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDA	2.3	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDB	2.3	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDC	2.3	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDD	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	6EGFB	2.61	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	9AXHC	2.81	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	9AXHD	2.81	Inactive	DFGin	BLBplus	out-none	none-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUWB	2.88	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUXA	3.34	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUYB	3.096	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUZA	3.21	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JV0A	3.63	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JV1D	3.62	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JURB	2.82	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUSB	2.99	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUTB	3.09	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUUB	3.19	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUVB	3.36	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7UMBB	3.231	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVJA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVKA	3.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVKC	3.5	Inactive	DFGin	None	in-out	in-in	ANP	Type1
TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH5A	4.0	Inactive	DFGinter	None	out-out	out-in	ANP	Type1
TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH5C	4.0	Inactive	DFGinter	None	out-out	out-in	ANP	Type1
TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH4A	4.1	Inactive	None	None	out-none	out-in	ANP	Type1
TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	9AY7A	2.41	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TKL	TGFBR2	TGFR2_HUMAN	TGF-beta receptor type-2	5E92A	2.08	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3VJNA	2.34	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITXA	2.98	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3VJOA	2.64	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITNA	2.47	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITVA	2.47	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2EB3A	2.84	Inactive	DFGin	BLAplus	in-in	in-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LB	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKA	2.4	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKD	2.4	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3A	2.1	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV4C	2.2	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3B	2.49	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4B	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSED	1.97	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5D41B	2.31	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AD	1.85	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXKB	3.1	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMC	2.192	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNOB	1.55	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNNA	1.9	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DB	2.4	Inactive	DFGin	BLBplus	out-out	out-out	ANP NQ1	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LA	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LC	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LD	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P8QA	1.9	Inactive	DFGin	BLBplus	out-out	out-in	ANP O57	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6XL4D	2.06	Inactive	DFGin	BLBplus	out-out	out-in	ANP NQ1	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4C	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP IXR	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4D	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP IXR	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5D41A	2.31	Inactive	DFGin	BLBplus	out-out	none-in	ANP 57N	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKA	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKB	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKC	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKD	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKE	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKF	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXKD	3.1	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMD	2.192	Inactive	DFGin	BLBplus	out-out	none-in	ANP 9LL	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPA	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPB	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPD	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPF	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQB	1.83	Inactive	DFGin	BLBplus	out-out	out-in	ANP VNS	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQD	1.83	Inactive	DFGin	BLBplus	out-out	out-in	ANP VNS	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXA	2.3	Inactive	DFGin	BLBplus	out-out	none-out	ANP YFA	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXB	2.3	Inactive	DFGin	BLBplus	out-out	out-in	ANP YFA	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXC	2.3	Inactive	DFGin	BLBplus	out-out	none-in	ANP YFA	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXD	2.3	Inactive	DFGin	BLBplus	out-out	out-in	ANP YFA	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4A	2.59	Inactive	DFGin	BLBplus	out-out	none-out	ANP YW5	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4B	2.59	Inactive	DFGin	BLBplus	out-out	none-none	ANP YW5	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4C	2.59	Inactive	DFGin	BLBplus	out-out	none-out	ANP YW5	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4D	2.59	Inactive	DFGin	BLBplus	out-out	none-none	ANP YW5	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7K1IA	3.202	Inactive	DFGin	BLBplus	out-out	none-in	ANP VNS	Type1 Type3
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DC	2.4	Inactive	DFGin	BLBplus	out-out	out-in	NQ1 ANP	Type3 Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DD	2.4	Inactive	DFGin	BLBplus	out-out	out-in	NQ1 ANP	Type3 Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQA	1.83	Inactive	DFGin	BLBplus	out-out	out-out	VNS ANP	Type3 Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQC	1.83	Inactive	DFGin	BLBplus	out-out	out-in	VNS ANP	Type3 Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DA	2.4	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKB	2.4	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WXNB	1.76	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3B	2.1	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3D	2.1	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV4A	2.2	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3C	2.49	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3D	2.49	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4A	2.99	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEA	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEB	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEC	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMA	2.192	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2GS7A	2.6	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2GS7B	2.6	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8A	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8B	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8C	2.955	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8D	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNOA	1.55	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNNB	1.9	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AA	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Allosteric
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AB	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8DSWA	2.39	Inactive	None	None	none-none	in-in	ANP	Type1
TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	1MQBA	2.3	None	DFGin	BLAminus	in-out	none-in	ANP	Type1
TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	1MQBB	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	5I9WA	1.359	Inactive	DFGin	BLBminus	in-in	none-in	ANP	Type1
TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QOCA	1.25	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	3FXXA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QO7A	1.605	None	DFGin	BLAminus	in-out	none-none	ANP	Type1
TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QO9A	1.55	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QOQA	1.6	None	DFGin	BLAminus	in-in	none-in	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3KEXA	2.797	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3KEXB	2.797	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIWA	3.1	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIWC	3.1	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3LMGA	2.8	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3LMGB	2.8	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIYA	2.981	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIYC	2.981	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIXA	3.1	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIXC	3.1	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
TYR	FGFR2	FGFR2_HUMAN	Fibroblast growth factor receptor 2	5UGLA	1.861	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	FGFR2	FGFR2_HUMAN	Fibroblast growth factor receptor 2	5UGLB	1.861	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	HCK	HCK_HUMAN	Tyrosine-protein kinase HCK	1AD5A	2.6	Inactive	DFGin	BLAminus	out-out	out-out	ANP	Type1
TYR	HCK	HCK_HUMAN	Tyrosine-protein kinase HCK	1AD5B	2.6	Inactive	DFGin	BLAminus	out-out	out-out	ANP	Type1
TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHA	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHB	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHC	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
TYR	INSR	INSR_HUMAN	Insulin receptor	1IR3A	1.9	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
TYR	LCK	LCK_HUMAN	Tyrosine-protein kinase Lck	1QPCA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	MERTK	MERTK_HUMAN	Tyrosine-protein kinase Mer	2P0CA	2.4	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
TYR	MERTK	MERTK_HUMAN	Tyrosine-protein kinase Mer	2P0CB	2.4	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
TYR	MST1R	RON_HUMAN	Macrophage-stimulating protein receptor	3PLSA	2.24	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	MST1R	RON_HUMAN	Macrophage-stimulating protein receptor	8ZKDA	2.05	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	SRC	SRC_HUMAN	Proto-oncogene tyrosine-protein kinase Src	2SRCA	1.5	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL1A	1.79	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL3A	1.9	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL2A	2.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
TYR	ZAP70	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	2OZOA	2.6	Inactive	DFGin	BLAplus	out-out	out-none	ANP	Type1
TYR	ZAP70	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	4K2RA	3.0	Inactive	DFGin	BLAplus	out-out	none-out	ANP	Type1

Protein kinases in complex with ANP

Total number of genes: 117

Total number of chains: 513

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	218	8QCGA
DFGin	BLAplus	5	2OZOA
DFGin	ABAminus	34	4C2WA
DFGin	BLBminus	11	4LGDA
DFGin	BLBplus	151	2SRCA
DFGin	BLBtrans	34	5X2AB
DFGin	None	35	6BXIA
DFGinter	None	10	7OPOG
DFGout	None	4	4I94A
None	None	11	4JQEA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Arabidopsis thaliana	CMGC	CKA1	CSK21_ARATH	Casein kinase II subunit alpha-1	6XX7A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	CMGC	MPK4	MPK4_ARATH	Mitogen-activated protein kinase 4	7W5CA	2.201	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Arabidopsis thaliana	OTHER	BSK8	BSK8_ARATH	Serine/threonine-protein kinase BSK8	4I94A	1.8	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Arabidopsis thaliana	OTHER	BSK8	BSK8_ARATH	Serine/threonine-protein kinase BSK8	4I94B	1.8	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Arabidopsis thaliana	TKL	BAK1	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	3UIMA	2.2	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	5LPVA	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4OH4A	2.25	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4OH4B	2.25	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4Q5JA	2.772	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4Q5JB	2.772	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	CARK1	CARK1_ARATH	Receptor-like cytoplasmic kinase 1	5XD6A	1.898	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Arabidopsis thaliana	TKL	CARK1	CARK1_ARATH	Receptor-like cytoplasmic kinase 1	5XD6B	1.898	Inactive	DFGin	None	out-none	none-none	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTVA	2.886	Inactive	DFGin	BLBminus	out-none	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTVB	2.886	Inactive	DFGin	BLBminus	out-none	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTXA	2.907	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTXB	2.907	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW5G	3.8	None	DFGin	BLAminus	out-none	in-in	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW8G	3.5	None	DFGin	BLAminus	in-none	in-in	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW7G	6.0	Inactive	None	None	out-none	in-out	ANP	Type1
Caenorhabditis elegans	TYR	LET23	LET23_CAEEL	Receptor tyrosine-protein kinase let-23	5WNOA	2.386	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Cryptococcus neoformans	CMGC	CK2	Q5KF69_CRYNJ	Casein kinase II subunit alpha	6ISEA	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptococcus neoformans	CMGC	CK2	Q5KF69_CRYNJ	Casein kinase II subunit alpha	6ISEB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptococcus neoformans	CMGC	CKA1	J9VNH4_CRYNH	Casein kinase II subunit alpha	6KO6B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK1	A3FQ16_CRYPI	non-specific serine/threonine protein kinase	3IGOA	2.25	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK3	Q5CS01_CRYPI	Calcium-dependent protein kinase 1	3LIJA	1.9	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK4	Q5CZ29_CRYPI	non-specific serine/threonine protein kinase	3HKOA	1.8	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Drosophila melanogaster	CMGC	BSK	JNK_DROME	Stress-activated protein kinase JNK	5AWMA	1.79	Inactive	DFGin	ABAminus	out-out	out-out	ANP	Type1
Drosophila melanogaster	STE	DSOR1	DSOR1_DROME	Dual specificity mitogen-activated protein kinase kinase dSOR1	8BW9C	3.32	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	2J0LA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	6TY4A	5.96	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	6TY4B	5.96	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	AKT1	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	4EKKA	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	AKT1	AKT1_HUMAN	RAC-alpha serine/threonine-protein kinase	4EKKB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	AKT2	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	1O6KA	1.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	AKT2	AKT2_HUMAN	RAC-beta serine/threonine-protein kinase	1O6LA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	GRK5	GRK5_HUMAN	G protein-coupled receptor kinase 5	4TNDA	1.802	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	GRK6	GRK6_HUMAN	G protein-coupled receptor kinase 6	2ACXA	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	GRK6	GRK6_HUMAN	G protein-coupled receptor kinase 6	2ACXB	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKCI	KPCI_HUMAN	Protein kinase C iota type	8R3YI	3.68	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Homo sapiens	AGC	PRKCI	KPCI_HUMAN	Protein kinase C iota type	5LI1A	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2A	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2B	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2C	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	6BG2D	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	7LV3A	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	PRKG1	KGP1_HUMAN	cGMP-dependent protein kinase 1	7LV3B	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2V55A	3.705	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2V55C	3.705	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	AGC	RPS6KA1	KS6A1_HUMAN	Ribosomal protein S6 kinase alpha-1	8XOVA	2.55	Inactive	DFGin	BLAplus	out-out	out-out	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOA	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOE	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOI	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOK	2.75	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOC	2.75	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
Homo sapiens	AGC	RPS6KA3	KS6A3_HUMAN	Ribosomal protein S6 kinase alpha-3	7OPOG	2.75	Inactive	DFGinter	None	out-out	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G77A	2.499	Inactive	DFGin	None	none-none	out-in	ANP ANP	Allosteric Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G77B	2.499	Inactive	DFGin	None	none-none	out-in	ANP ANP	Allosteric Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G76B	3.0	Inactive	DFGinter	None	none-none	out-none	ANP	Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G78A	2.5	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G78B	2.5	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
Homo sapiens	AGC	RPS6KA6	KS6A6_HUMAN	Ribosomal protein S6 kinase alpha-6	6G76A	3.0	Inactive	DFGinter	None	none-none	out-in	ANP ANP	Type1 Allosteric
Homo sapiens	AGC	SGK1	SGK1_HUMAN	Serine/threonine-protein kinase Sgk1	2R5TA	1.9	Inactive	DFGinter	None	none-none	out-out	ANP	Type1
Homo sapiens	AGC	STK38	STK38_HUMAN	Serine/threonine-protein kinase 38	6BXIA	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	AGC	STK38	STK38_HUMAN	Serine/threonine-protein kinase 38	6BXIB	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	2DWBA	2.5	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPGA	2.64	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPIA	2.0	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPLA	1.86	Inactive	DFGin	BLAminus	out-out	in-out	ANP R7D	Type1 Allosteric
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPLB	1.86	Inactive	DFGin	BLAminus	out-out	in-out	ANP R7D	Type1 Allosteric
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	2C6DA	2.2	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPJA	2.1	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Homo sapiens	CAMK	AURKA	AURKA_HUMAN	Aurora kinase A	6VPHA	2.14	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Homo sapiens	CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFRA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFSA	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	CASK	CSKP_HUMAN	Peripheral plasma membrane protein CASK	3MFUA	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	CHEK1	CHK1_HUMAN	Serine/threonine-protein kinase Chk1	5OOPA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1IG1A	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1JKKA	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	1JKLA	1.62	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3EHAA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3F5UA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3DFCB	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3GU4A	1.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	DAPK1	DAPK1_HUMAN	Death-associated protein kinase 1	3GU5A	1.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	MELK	MELK_HUMAN	Maternal embryonic leucine zipper kinase	4BL1A	2.6	Inactive	DFGin	ABAminus	in-in	in-none	ANP	Type1
Homo sapiens	CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	1YXTA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	1XR1A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	3A99A	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	PIM1	PIM1_HUMAN	Serine/threonine-protein kinase pim-1	2BZKB	2.45	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	PLK1	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	8X72A	2.2	Inactive	DFGin	BLAminus	out-in	in-out	ANP	Type1
Homo sapiens	CAMK	PLK1	PLK1_HUMAN	Serine/threonine-protein kinase PLK1	2OU7A	2.4	Inactive	DFGin	BLAminus	out-in	in-out	ANP	Type1
Homo sapiens	CAMK	PLK4	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	3COKA	2.25	None	DFGin	BLAminus	in-out	in-none	ANP	Type1
Homo sapiens	CAMK	PLK4	PLK4_HUMAN	Serine/threonine-protein kinase PLK4	3COKB	2.25	None	DFGin	BLAminus	in-out	in-none	ANP	Type1
Homo sapiens	CAMK	RPS6KA5	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	3KN5A	2.4	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
Homo sapiens	CAMK	RPS6KA5	KS6A5_HUMAN	Ribosomal protein S6 kinase alpha-5	3KN5B	2.4	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
Homo sapiens	CAMK	STK11	STK11_HUMAN	Serine/threonine-protein kinase STK11	2WTKC	2.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CAMK	STK11	STK11_HUMAN	Serine/threonine-protein kinase STK11	2WTKF	2.65	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9A	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9B	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9C	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CK1	VRK1	VRK1_HUMAN	Serine/threonine-protein kinase VRK1	6AC9D	2.07	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	4CXAA	3.15	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R99A	1.81	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BA	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BB	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BC	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CMGC	CDK7	CDK7_HUMAN	Cyclin-dependent kinase 7	8R9BD	2.21	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	CMGC	CDK9	CDK9_HUMAN	Cyclin-dependent kinase 9	3MIAA	3.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3JUHA	1.66	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3JUHB	1.66	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3NSZA	1.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	1PJKA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	2PVRA	1.605	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3WOWA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	1JWHA	3.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3U87A	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A1	CSK21_HUMAN	Casein kinase II subunit alpha	3U87B	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A2	CSK22_HUMAN	Casein kinase II subunit alpha'	8QCGA	1.04	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	CMGC	CSNK2A2	CSK22_HUMAN	Casein kinase II subunit alpha'	8QCGB	1.04	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	DYRK1A	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	7A4OA	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	DYRK1A	DYR1A_HUMAN	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	7A4OB	1.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1J1BA	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1J1BB	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	8XN6A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	8XN6B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1PYXA	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	GSK3B	GSK3B_HUMAN	Glycogen synthase kinase-3 beta	1PYXB	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT3A	1.8	Inactive	DFGin	BLAminus	in-out	in-out	D7O ANP	Allosteric Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3QA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	6OPGA	2.9	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	2Y9QA	1.55	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4FMQA	2.098	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4NIFB	2.15	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4NIFE	2.15	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PSRA	1.85	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	3TEIA	2.404	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3PA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	4H3PD	2.3	None	DFGin	BLAminus	in-in	in-none	ANP	Type1
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT0A	1.65	Inactive	DFGin	BLAminus	in-in	in-out	ANP EAI	Type1 Allosteric
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT1A	1.8	Inactive	DFGin	BLAminus	in-in	in-out	ANP E2A	Type1 Allosteric
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8PT5A	1.95	Inactive	DFGin	BLAminus	in-in	in-out	ANP D5R	Type1 Allosteric
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	8R5FA	1.65	Inactive	DFGin	BLAminus	in-in	in-out	ANP Y3H	Type1 Allosteric
Homo sapiens	CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	4Z9LA	2.1	Inactive	DFGin	ABAminus	out-out	none-out	ANP 880	Allosteric Type1
Homo sapiens	CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	8WGFA	1.85	Inactive	DFGin	ABAminus	in-out	out-out	ANP	Type1
Homo sapiens	CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	1JNKA	2.3	Inactive	DFGin	ABAminus	in-out	none-out	ANP	Type1
Homo sapiens	CMGC	MAPK12	MK12_HUMAN	Mitogen-activated protein kinase 12	1CM8A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK12	MK12_HUMAN	Mitogen-activated protein kinase 12	1CM8B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK7	MK07_HUMAN	Mitogen-activated protein kinase 7	4IC7A	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK7	MK07_HUMAN	Mitogen-activated protein kinase 7	4IC7D	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	6ZR5A	2.699	Inactive	DFGin	ABAminus	out-out	out-none	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	6ZR5B	2.699	Inactive	DFGin	ABAminus	out-out	out-out	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	2XRWA	1.33	Inactive	DFGin	ABAminus	in-out	none-none	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	2XS0A	2.6	Inactive	DFGin	ABAminus	in-out	none-none	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9A	2.34	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9C	2.34	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9D	2.34	Inactive	DFGin	ABAminus	in-in	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	8R5EA	1.7	Inactive	DFGin	ABAminus	in-out	out-out	ANP Y6K	Type1 Allosteric
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4QTDA	1.5	Inactive	DFGin	ABAminus	in-out	out-out	38Z ANP	Type1 Allosteric
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	9FT9A	2.35	Inactive	DFGin	BLAminus	in-out	in-out	ANP	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	4UX9B	2.34	Inactive	DFGin	None	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	PRP4K	PRP4K_HUMAN	Serine/threonine-protein kinase PRP4 homolog	4IIRA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	PRP4K	PRP4K_HUMAN	Serine/threonine-protein kinase PRP4 homolog	4IIRB	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	CMGC	SRPK1	SRPK1_HUMAN	SRSF protein kinase 1	3BEGA	2.9	None	DFGin	BLAminus	in-none	in-in	ANP	Type1
Homo sapiens	OTHER	EIF2AK2	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	2A19B	2.5	Inactive	DFGin	ABAminus	in-in	in-out	ANP	Type1
Homo sapiens	OTHER	EIF2AK2	E2AK2_HUMAN	Interferon-induced, double-stranded RNA-activated protein kinase	2A19C	2.5	Inactive	DFGin	ABAminus	in-in	none-none	ANP	Type1
Homo sapiens	OTHER	TP53RK	PRPK_HUMAN	EKC/KEOPS complex subunit TP53RK	6WQXC	2.53	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1
Homo sapiens	OTHER	TP53RK	PRPK_HUMAN	EKC/KEOPS complex subunit TP53RK	6WQXD	2.53	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WDYA	2.458	None	DFGin	BLAminus	out-none	in-none	ANP A6S	Type1 Type3
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WDYB	2.458	None	DFGin	BLAminus	out-none	in-none	ANP A6S	Type1 Type3
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WE8A	2.006	Inactive	DFGin	BLAminus	out-none	in-out	ANP A7Y	Type1 Type3
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5WE8B	2.006	Inactive	DFGin	BLAminus	out-none	in-out	ANP A7Y	Type1 Type3
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5TF9A	2.5	Inactive	DFGin	BLAminus	out-none	in-out	7AV ANP	Type3 Type1
Homo sapiens	OTHER	WNK1	WNK1_HUMAN	Serine/threonine-protein kinase WNK1	5TF9B	2.5	Inactive	DFGin	BLAminus	out-none	in-out	7AV ANP	Type3 Type1
Homo sapiens	OTHER	WNK3	WNK3_HUMAN	Serine/threonine-protein kinase WNK3	5O26A	2.379	Active	DFGin	BLAminus	out-none	in-in	ANP	Type1
Homo sapiens	OTHER	WNK3	WNK3_HUMAN	Serine/threonine-protein kinase WNK3	5O26B	2.379	Active	DFGin	BLAminus	out-none	in-in	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3C	2.9	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	6V2WB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXHA	2.81	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXHB	2.81	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXMA	2.42	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXXA	2.07	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXXC	2.07	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AYAB	2.59	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AYAD	2.59	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AY7B	2.41	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type1 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3SLSA	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP 77D	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3SLSB	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP 77D	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B3MA	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP SU5	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B3MB	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP SU5	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B7RA	1.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP T1K	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B7RB	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T1K	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B94A	2.0	Inactive	DFGin	BLBplus	out-out	out-out	ANP T3W	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B94B	2.0	Inactive	DFGin	BLBplus	out-out	out-none	ANP T3W	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B9LA	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T4N	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7B9LB	1.7	Inactive	DFGin	BLBplus	out-out	out-none	ANP T4N	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3ORNA	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3OR	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	3WIGA	2.7	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U80A	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EX	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4LMNA	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7UMBC	3.231	Inactive	DFGin	BLBplus	out-out	out-out	ANP U9F	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	6PP9B	2.59	Inactive	DFGin	BLBplus	out-out	out-out	ANP LCJ	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0VB	3.16	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0WB	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOA	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0XB	2.47	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0YB	3.45	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0ZB	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP CHU	Type1 Type3
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U7ZA	2.805	Inactive	DFGin	BLBplus	out-out	out-out	3EW ANP	Type3 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	4U81A	2.701	Inactive	DFGin	BLBplus	out-out	out-out	3EY ANP	Type3 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	9AXYB	3.6	Inactive	DFGin	BLBplus	out-out	out-out	A1AHE ANP	Type3 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0TB	3.19	Inactive	DFGin	BLBplus	out-out	out-out	3EW ANP	Type3 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7M0UB	3.09	Inactive	DFGin	BLBplus	out-out	out-out	QO7 ANP	Type3 Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3B	2.9	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3D	2.9	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	5YT3A	2.9	Inactive	DFGinter	None	out-out	none-none	ANP	Type1
Homo sapiens	STE	MAP2K1	MP2K1_HUMAN	Dual specificity mitogen-activated protein kinase kinase 1	7F2XA	2.007	Inactive	None	None	out-out	out-out	ANP	Type1
Homo sapiens	STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNA	2.3	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
Homo sapiens	STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNB	2.3	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
Homo sapiens	STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALOA	2.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	STE	MAP2K4	MP2K4_HUMAN	Dual specificity mitogen-activated protein kinase kinase 4	3ALNC	2.3	Inactive	None	None	none-none	none-none	ANP	Type1
Homo sapiens	STE	MAP4K1	M4K1_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 1	6CQDA	2.12	Inactive	DFGin	BLAminus	in-in	out-out	ANP	Type1
Homo sapiens	STE	MAP4K1	M4K1_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 1	6CQDB	2.12	Inactive	DFGin	BLAminus	in-in	out-out	ANP	Type1
Homo sapiens	STE	MAP4K4	M4K4_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 4	4U40A	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKA	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKB	2.25	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKC	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	3DAKD	2.25	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIB	2.15	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIC	2.15	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWID	2.15	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	STE	OXSR1	OXSR1_HUMAN	Serine/threonine-protein kinase OSR1	2VWIA	2.15	Inactive	DFGin	None	none-none	out-out	ANP	Type1
Homo sapiens	STE	PAK1	PAK1_HUMAN	Serine/threonine-protein kinase PAK 1	3Q4ZA	1.887	None	DFGin	BLAminus	out-none	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIFA	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIFB	2.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIGA	3.01	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4JDIA	1.85	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	5UPKB	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIEA	3.11	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIEB	3.11	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	7S46A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	7S47A	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	PAK4	PAK4_HUMAN	Serine/threonine-protein kinase PAK 4	4FIGB	3.01	Inactive	DFGin	None	in-in	in-in	ANP	Type1
Homo sapiens	STE	STK24	STK24_HUMAN	Serine/threonine-protein kinase 24	4QMLA	1.882	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	6AO5A	2.955	Inactive	DFGin	BLAplus	out-out	none-out	ANP	Type1
Homo sapiens	STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDA	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
Homo sapiens	STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDB	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
Homo sapiens	STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDC	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
Homo sapiens	STE	STK3	STK3_HUMAN	Serine/threonine-protein kinase 3	4LGDD	3.05	Inactive	DFGin	BLBminus	out-out	out-out	ANP	Type1
Homo sapiens	STE	STRADA	STRAA_HUMAN	STE20-related kinase adapter protein alpha	2WTKB	2.65	None	DFGin	BLAminus	out-none	in-out	ANP	Type1
Homo sapiens	STE	STRADA	STRAA_HUMAN	STE20-related kinase adapter protein alpha	2WTKE	2.65	None	DFGin	BLAminus	in-none	in-out	ANP	Type1
Homo sapiens	STE	TNIK	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	7XZRB	2.26	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	STE	TNIK	TNIK_HUMAN	TRAF2 and NCK-interacting protein kinase	7XZRA	2.26	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1.5_Front
Homo sapiens	TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	6UNQA	2.4	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	6UNRA	2.2	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TKL	ARAF	ARAF_HUMAN	Serine/threonine-protein kinase A-Raf	9AXMB	2.42	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	9AXXB	2.07	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	9AXYA	3.6	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6PP9A	2.59	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	6V2WA	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0TA	3.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0UA	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0VA	3.16	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0WA	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0XA	2.47	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0YA	3.45	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	BRAF	BRAF_HUMAN	Serine/threonine-protein kinase B-raf	7M0ZA	3.12	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDA	2.3	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Homo sapiens	TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDB	2.3	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDC	2.3	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	2OIDD	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TKL	IRAK4	IRAK4_HUMAN	Interleukin-1 receptor-associated kinase 4	6EGFB	2.61	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	9AXHC	2.81	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	9AXHD	2.81	Inactive	DFGin	BLBplus	out-none	none-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUWB	2.88	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUXA	3.34	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUYB	3.096	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JUZA	3.21	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JV0A	3.63	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR1	KSR1_HUMAN	Kinase suppressor of Ras 1	7JV1D	3.62	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JURB	2.82	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUSB	2.99	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUTB	3.09	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUUB	3.19	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7JUVB	3.36	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	KSR2	KSR2_HUMAN	Kinase suppressor of Ras 2	7UMBB	3.231	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVJA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Homo sapiens	TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVKA	3.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TKL	LIMK1	LIMK1_HUMAN	LIM domain kinase 1	5HVKC	3.5	Inactive	DFGin	None	in-out	in-in	ANP	Type1
Homo sapiens	TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH5A	4.0	Inactive	DFGinter	None	out-out	out-in	ANP	Type1
Homo sapiens	TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH5C	4.0	Inactive	DFGinter	None	out-out	out-in	ANP	Type1
Homo sapiens	TKL	LRRK2	LRRK2_HUMAN	Leucine-rich repeat serine/threonine-protein kinase 2	8VH4A	4.1	Inactive	None	None	out-none	out-in	ANP	Type1
Homo sapiens	TKL	RAF1	RAF1_HUMAN	RAF proto-oncogene serine/threonine-protein kinase	9AY7A	2.41	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TKL	TGFBR2	TGFR2_HUMAN	TGF-beta receptor type-2	5E92A	2.08	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3VJNA	2.34	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITXA	2.98	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3VJOA	2.64	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITNA	2.47	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2ITVA	2.47	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2EB3A	2.84	Inactive	DFGin	BLAplus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LB	2.8	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKA	2.4	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKD	2.4	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3A	2.1	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV4C	2.2	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3B	2.49	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4B	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSED	1.97	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5D41B	2.31	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AD	1.85	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXKB	3.1	Inactive	DFGin	BLBplus	out-out	none-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMC	2.192	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNOB	1.55	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNNA	1.9	Inactive	DFGin	BLBplus	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DB	2.4	Inactive	DFGin	BLBplus	out-out	out-out	ANP NQ1	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LA	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LC	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1LD	2.8	Inactive	DFGin	BLBplus	out-out	none-out	ANP 9LL	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P8QA	1.9	Inactive	DFGin	BLBplus	out-out	out-in	ANP O57	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6XL4D	2.06	Inactive	DFGin	BLBplus	out-out	out-in	ANP NQ1	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4C	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP IXR	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4D	2.99	Inactive	DFGin	BLBplus	out-out	none-in	ANP IXR	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5D41A	2.31	Inactive	DFGin	BLBplus	out-out	none-in	ANP 57N	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKA	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKB	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKC	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKD	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKE	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6DUKF	2.2	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXKD	3.1	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMD	2.192	Inactive	DFGin	BLBplus	out-out	none-in	ANP 9LL	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPA	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPB	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPD	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXPF	2.16	Inactive	DFGin	BLBplus	out-out	out-in	ANP JBJ	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQB	1.83	Inactive	DFGin	BLBplus	out-out	out-in	ANP VNS	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQD	1.83	Inactive	DFGin	BLBplus	out-out	out-in	ANP VNS	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXA	2.3	Inactive	DFGin	BLBplus	out-out	none-out	ANP YFA	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXB	2.3	Inactive	DFGin	BLBplus	out-out	out-in	ANP YFA	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXC	2.3	Inactive	DFGin	BLBplus	out-out	none-in	ANP YFA	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7LTXD	2.3	Inactive	DFGin	BLBplus	out-out	out-in	ANP YFA	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4A	2.59	Inactive	DFGin	BLBplus	out-out	none-out	ANP YW5	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4B	2.59	Inactive	DFGin	BLBplus	out-out	none-none	ANP YW5	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4C	2.59	Inactive	DFGin	BLBplus	out-out	none-out	ANP YW5	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8GB4D	2.59	Inactive	DFGin	BLBplus	out-out	none-none	ANP YW5	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7K1IA	3.202	Inactive	DFGin	BLBplus	out-out	none-in	ANP VNS	Type1 Type3
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DC	2.4	Inactive	DFGin	BLBplus	out-out	out-in	NQ1 ANP	Type3 Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DD	2.4	Inactive	DFGin	BLBplus	out-out	out-in	NQ1 ANP	Type3 Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQA	1.83	Inactive	DFGin	BLBplus	out-out	out-out	VNS ANP	Type3 Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXQC	1.83	Inactive	DFGin	BLBplus	out-out	out-in	VNS ANP	Type3 Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6P1DA	2.4	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WAKB	2.4	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	6WXNB	1.76	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3B	2.1	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV3D	2.1	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8FV4A	2.2	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3C	2.49	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO3D	2.49	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8TO4A	2.99	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEA	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEB	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	4ZSEC	1.97	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	7JXMA	2.192	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2GS7A	2.6	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	2GS7B	2.6	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8A	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8B	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8C	2.955	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	3GT8D	2.955	Inactive	DFGin	BLBtrans	out-out	out-none	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNOA	1.55	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5CNNB	1.9	Inactive	DFGin	BLBtrans	out-out	out-out	ANP	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AA	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Allosteric
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AB	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	8DSWA	2.39	Inactive	None	None	none-none	in-in	ANP	Type1
Homo sapiens	TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	1MQBA	2.3	None	DFGin	BLAminus	in-out	none-in	ANP	Type1
Homo sapiens	TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	1MQBB	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	EPHA2	EPHA2_HUMAN	Ephrin type-A receptor 2	5I9WA	1.359	Inactive	DFGin	BLBminus	in-in	none-in	ANP	Type1
Homo sapiens	TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QOCA	1.25	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	3FXXA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QO7A	1.605	None	DFGin	BLAminus	in-out	none-none	ANP	Type1
Homo sapiens	TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QO9A	1.55	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	EPHA3	EPHA3_HUMAN	Ephrin type-A receptor 3	2QOQA	1.6	None	DFGin	BLAminus	in-in	none-in	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3KEXA	2.797	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3KEXB	2.797	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIWA	3.1	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIWC	3.1	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3LMGA	2.8	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	3LMGB	2.8	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIYA	2.981	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIYC	2.981	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIXA	3.1	Inactive	DFGin	BLBplus	out-none	out-none	ANP	Type1
Homo sapiens	TYR	ERBB3	ERBB3_HUMAN	Receptor tyrosine-protein kinase erbB-3	4RIXC	3.1	Inactive	DFGin	BLBplus	out-none	out-out	ANP	Type1
Homo sapiens	TYR	FGFR2	FGFR2_HUMAN	Fibroblast growth factor receptor 2	5UGLA	1.861	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	FGFR2	FGFR2_HUMAN	Fibroblast growth factor receptor 2	5UGLB	1.861	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	HCK	HCK_HUMAN	Tyrosine-protein kinase HCK	1AD5A	2.6	Inactive	DFGin	BLAminus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	HCK	HCK_HUMAN	Tyrosine-protein kinase HCK	1AD5B	2.6	Inactive	DFGin	BLAminus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHA	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
Homo sapiens	TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHB	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
Homo sapiens	TYR	IGF1R	IGF1R_HUMAN	Insulin-like growth factor 1 receptor	1JQHC	2.1	Inactive	DFGin	None	in-out	none-in	ANP	Type1
Homo sapiens	TYR	INSR	INSR_HUMAN	Insulin receptor	1IR3A	1.9	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Homo sapiens	TYR	LCK	LCK_HUMAN	Tyrosine-protein kinase Lck	1QPCA	1.6	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	MERTK	MERTK_HUMAN	Tyrosine-protein kinase Mer	2P0CA	2.4	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
Homo sapiens	TYR	MERTK	MERTK_HUMAN	Tyrosine-protein kinase Mer	2P0CB	2.4	Inactive	DFGin	BLBplus	out-none	none-none	ANP	Type1
Homo sapiens	TYR	MST1R	RON_HUMAN	Macrophage-stimulating protein receptor	3PLSA	2.24	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	MST1R	RON_HUMAN	Macrophage-stimulating protein receptor	8ZKDA	2.05	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	SRC	SRC_HUMAN	Proto-oncogene tyrosine-protein kinase Src	2SRCA	1.5	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL1A	1.79	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Homo sapiens	TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL3A	1.9	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
Homo sapiens	TYR	SYK	KSYK_HUMAN	Tyrosine-protein kinase SYK	4FL2A	2.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Homo sapiens	TYR	ZAP70	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	2OZOA	2.6	Inactive	DFGin	BLAplus	out-out	out-none	ANP	Type1
Homo sapiens	TYR	ZAP70	ZAP70_HUMAN	Tyrosine-protein kinase ZAP-70	4K2RA	3.0	Inactive	DFGin	BLAplus	out-out	none-out	ANP	Type1
Leishmania donovani	CMGC	MAPK	A0A3Q8ITZ9_LEIDO	Mitogen activated protein kinase, putative	4QNYA	2.257	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Leishmania donovani	CMGC	MAPK	A0A3Q8ITZ9_LEIDO	Mitogen activated protein kinase, putative	4QNYB	2.257	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Medicago truncatula	TKL	LYK3	LYK3_MEDTR	LysM domain receptor-like kinase 3	9GFZA	2.5	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Medicago truncatula	TKL	LYR4	G7K7K0_MEDTR	LysM-domain receptor-like kinase	8PS7B	2.1	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Medicago truncatula	TKL	LYR4	G7K7K0_MEDTR	LysM-domain receptor-like kinase	8PS7A	2.1	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Methanocaldococcus jannaschii	OTHER	BUD32	KAE1B_METJA	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	2VWBA	3.05	Inactive	DFGin	None	in-in	in-none	ANP	Allosteric
Methanocaldococcus jannaschii	OTHER	BUD32	KAE1B_METJA	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	2VWBB	3.05	Inactive	DFGin	None	in-in	in-none	ANP	Allosteric
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM6C	2.39	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM6E	2.39	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM7A	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM7D	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM8C	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKND	2.75	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKOE	2.89	Inactive	DFGin	ABAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKPE	2.85	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E11A	3.43	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM5E	1.95	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3PVBA	3.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	2QCSA	2.2	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3IDBA	1.62	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3IDCA	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DG0E	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DH7A	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DH8A	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4HPTE	2.15	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4HPUE	1.55	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DFXE	1.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4XW4A	1.82	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E0ZA	2.162	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E12A	2.796	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DG3E	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3O7LB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3FHIA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	RPS6KA3	KS6A3_MOUSE	Ribosomal protein S6 kinase alpha-3	3G51A	1.8	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Mus musculus	CAMK	CAMK2A	KCC2A_MOUSE	Calcium/calmodulin-dependent protein kinase type II subunit alpha	7B56B	1.45	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	CAMK	MELK	MELK_MOUSE	Maternal embryonic leucine zipper kinase	4BFMA	2.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	OTHER	POMK	SG196_MOUSE	Protein O-mannose kinase	5GZ9A	2.4	Inactive	DFGin	ABAminus	none-none	in-out	ANP MAN	Type1 Allosteric
Mus musculus	STE	STK39	STK39_MOUSE	STE20/SPS1-related proline-alanine-rich protein kinase	5DBXA	2.5	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Mus musculus	STE	STK39	STK39_MOUSE	STE20/SPS1-related proline-alanine-rich protein kinase	5DBXB	2.5	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Mus musculus	TKL	RIPK3	RIPK3_MOUSE	Receptor-interacting serine/threonine-protein kinase 3	4M69A	2.497	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Mus musculus	TYR	EPHB2	EPHB2_MOUSE	Ephrin type-B receptor 2	1JPAA	1.91	Inactive	DFGin	None	in-in	none-none	ANP	Type1
Mus musculus	TYR	EPHB2	EPHB2_MOUSE	Ephrin type-B receptor 2	1JPAB	1.91	Inactive	DFGin	None	in-in	none-none	ANP	Type1
Mus musculus	TYR	LYN	LYN_MOUSE	Tyrosine-protein kinase Lyn	2ZV8A	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Neurospora crassa	OTHER	PAN3	PAN3_NEUCR	PAN2-PAN3 deadenylation complex subunit pan3	4CZYB	3.4	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Neurospora crassa	OTHER	PAN3	PAN3_NEUCR	PAN2-PAN3 deadenylation complex subunit pan3	4CZYD	3.4	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUWC	2.88	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JURC	2.82	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUTC	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EW	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUUC	3.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUVC	3.36	Inactive	DFGin	BLBplus	out-out	out-out	ANP VKG	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUXC	3.34	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUYC	3.096	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUZC	3.21	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EW	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JV0C	3.63	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JV1C	3.62	Inactive	DFGin	BLBplus	out-out	out-out	ANP VKG	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUSC	2.99	Inactive	DFGin	BLBplus	out-out	out-out	VKD ANP	Type3 Type1
Pediculus humanus	OTHER	PINK1	PINK1_PEDHC	Serine/threonine-protein kinase Pink1, mitochondrial	8UYHA	2.84	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Pediculus humanus	OTHER	PINK1	PINK1_PEDHC	Serine/threonine-protein kinase Pink1, mitochondrial	8UYHB	2.84	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium berghei	CAMK	CDPK1	CDPK1_PLABA	Calcium-dependent protein kinase 1	3Q5IA	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium falciparum	CMGC	MAPK	Q7KQK7_PLAF7	Mitogen-activated protein kinase	3NIEA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Plasmodium falciparum	CMGC	MAPK	Q7KQK7_PLAF7	Mitogen-activated protein kinase	3NIEB	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Plasmodium falciparum	CMGC	PSTK1	Q8IL19_PLAF7	Protein serine/threonine kinase-1	3LLTA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium falciparum	OTHER	PK7	O96214_PLAFA	mitogen-activated protein kinase kinase	2PMLX	2.6	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Plasmodium vivax	AGC	PKG	KGP_PLAVS	cGMP-dependent protein kinase	5DZCA	2.3	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Rattus norvegicus	AGC	PRKCB	KPCB_RAT	Protein kinase C beta type	3PFQA	4.0	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S33A	1.48	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S32A	1.34	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	7UGBA	1.9	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S34A	2.5	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQVA	2.19	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQXA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQWA	1.8	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	OTHER	WNK1	WNK1_RAT	Serine/threonine-protein kinase WNK1	5W7TA	2.01	Inactive	DFGin	BLBtrans	out-none	out-in	ANP	Type1
Rattus norvegicus	OTHER	WNK1	WNK1_RAT	Serine/threonine-protein kinase WNK1	5W7TB	2.01	Inactive	DFGin	BLBtrans	out-none	out-in	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQSA	3.3	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	5NCLA	3.15	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQPA	4.5	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQQA	3.6	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	4PDSA	2.9	None	DFGin	BLAminus	in-none	in-none	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	4PDSB	2.9	None	DFGin	BLAminus	in-none	in-none	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	5XZVB	3.1	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	5XZVA	3.1	Inactive	DFGin	None	in-out	out-none	ANP	Type1
Saccharomyces cerevisiae	CMGC	CKA1	CSK21_YEAST	Casein kinase II subunit alpha	4JQEA	1.77	Inactive	None	None	out-none	in-in	ANP	Type1
Saccharomyces cerevisiae	CMGC	SKY1	SKY1_YEAST	Serine/threonine-protein kinase SKY1	1Q99A	2.11	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Saccharomyces cerevisiae	CMGC	SKY1	SKY1_YEAST	Serine/threonine-protein kinase SKY1	1Q99B	2.11	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Saccharomyces cerevisiae	OTHER	BUD32	BUD32_YEAST	EKC/KEOPS complex subunit BUD32	4WW5A	1.997	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1.5_Front
Saccharomyces cerevisiae	OTHER	GCN2	GCN2_YEAST	eIF-2-alpha kinase GCN2	1ZY5A	2.0	Inactive	DFGin	BLBminus	out-out	out-none	ANP	Type1
Saccharomyces cerevisiae	OTHER	GCN2	GCN2_YEAST	eIF-2-alpha kinase GCN2	1ZY5B	2.0	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Sus scrofa	AGC	PRKACA	KAPCA_PIG	cAMP-dependent protein kinase catalytic subunit alpha	1CDKA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Sus scrofa	AGC	PRKACA	KAPCA_PIG	cAMP-dependent protein kinase catalytic subunit alpha	1CDKB	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PA	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PB	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PC	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PD	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	4IEBA	2.05	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	3HX4A	1.95	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	3KU2A	2.3	Inactive	None	None	out-none	out-out	ANP	Type1
Tribolium castaneum	OTHER	PINK1	PINK1_TRICA	Serine/threonine-protein kinase Pink1, mitochondrial	5YJ9D	2.53	Inactive	DFGin	ABAminus	in-in	in-in	ANP	Type1
Trichomonas vaginalis	CMGC	TVAG125560	A2F9N1_TRIV3	non-specific serine/threonine protein kinase	9AV7A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Xenopus laevis	CAMK	AURKBA	AUKBA_XENLA	Aurora kinase B-A	4C2WA	1.7	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Xenopus laevis	CAMK	AURKBA	AUKBA_XENLA	Aurora kinase B-A	4C2WB	1.7	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Zea mays	CMGC	ACK2	CSK2A_MAIZE	Casein kinase II subunit alpha	1DAWA	2.2	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Zea mays	CMGC	ACK2	CSK2A_MAIZE	Casein kinase II subunit alpha	1LP4A	1.86	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Zea mays	OTHER	SIRK1	K7VIQ3_MAIZE	Putative leucine-rich repeat protein kinase family protein	5UV4A	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1

Protein kinases in complex with ANP

Total number of genes: 46

Total number of chains: 135

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	68	4S32A
DFGin	ABAminus	18	4C2WA
DFGin	BLBminus	6	7CTVA
DFGin	BLBplus	18	7CTXB
DFGin	BLBtrans	3	5W7TA
DFGin	None	13	2VWBA
DFGout	None	2	4I94A
None	None	7	4JQEA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Arabidopsis thaliana	CMGC	CKA1	CSK21_ARATH	Casein kinase II subunit alpha-1	6XX7A	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	CMGC	MPK4	MPK4_ARATH	Mitogen-activated protein kinase 4	7W5CA	2.201	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Arabidopsis thaliana	OTHER	BSK8	BSK8_ARATH	Serine/threonine-protein kinase BSK8	4I94A	1.8	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Arabidopsis thaliana	OTHER	BSK8	BSK8_ARATH	Serine/threonine-protein kinase BSK8	4I94B	1.8	Inactive	DFGout	None	out-out	out-out	ANP	Type1
Arabidopsis thaliana	TKL	BAK1	BAK1_ARATH	BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1	3UIMA	2.2	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	5LPVA	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4OH4A	2.25	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4OH4B	2.25	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4Q5JA	2.772	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	BRI1	BRI1_ARATH	Protein BRASSINOSTEROID INSENSITIVE 1	4Q5JB	2.772	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Arabidopsis thaliana	TKL	CARK1	CARK1_ARATH	Receptor-like cytoplasmic kinase 1	5XD6A	1.898	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Arabidopsis thaliana	TKL	CARK1	CARK1_ARATH	Receptor-like cytoplasmic kinase 1	5XD6B	1.898	Inactive	DFGin	None	out-none	none-none	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTVA	2.886	Inactive	DFGin	BLBminus	out-none	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTVB	2.886	Inactive	DFGin	BLBminus	out-none	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTXA	2.907	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Arabidopsis thaliana	TKL	SOBIR1	SBIR1_ARATH	Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1	7CTXB	2.907	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW5G	3.8	None	DFGin	BLAminus	out-none	in-in	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW8G	3.5	None	DFGin	BLAminus	in-none	in-in	ANP	Type1
Bos taurus	AGC	PRKACA	KAPCA_BOVIN	cAMP-dependent protein kinase catalytic subunit alpha	9DW7G	6.0	Inactive	None	None	out-none	in-out	ANP	Type1
Caenorhabditis elegans	TYR	LET23	LET23_CAEEL	Receptor tyrosine-protein kinase let-23	5WNOA	2.386	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Cryptococcus neoformans	CMGC	CK2	Q5KF69_CRYNJ	Casein kinase II subunit alpha	6ISEA	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptococcus neoformans	CMGC	CK2	Q5KF69_CRYNJ	Casein kinase II subunit alpha	6ISEB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptococcus neoformans	CMGC	CKA1	J9VNH4_CRYNH	Casein kinase II subunit alpha	6KO6B	2.4	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK1	A3FQ16_CRYPI	non-specific serine/threonine protein kinase	3IGOA	2.25	Inactive	DFGin	BLBplus	out-out	out-none	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK3	Q5CS01_CRYPI	Calcium-dependent protein kinase 1	3LIJA	1.9	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Cryptosporidium parvum	CAMK	CDPK4	Q5CZ29_CRYPI	non-specific serine/threonine protein kinase	3HKOA	1.8	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Drosophila melanogaster	CMGC	BSK	JNK_DROME	Stress-activated protein kinase JNK	5AWMA	1.79	Inactive	DFGin	ABAminus	out-out	out-out	ANP	Type1
Drosophila melanogaster	STE	DSOR1	DSOR1_DROME	Dual specificity mitogen-activated protein kinase kinase dSOR1	8BW9C	3.32	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	2J0LA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	6TY4A	5.96	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Gallus gallus	TYR	PTK2	FAK1_CHICK	Focal adhesion kinase 1	6TY4B	5.96	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Leishmania donovani	CMGC	MAPK	A0A3Q8ITZ9_LEIDO	Mitogen activated protein kinase, putative	4QNYA	2.257	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Leishmania donovani	CMGC	MAPK	A0A3Q8ITZ9_LEIDO	Mitogen activated protein kinase, putative	4QNYB	2.257	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Medicago truncatula	TKL	LYK3	LYK3_MEDTR	LysM domain receptor-like kinase 3	9GFZA	2.5	Inactive	DFGin	BLBtrans	out-out	out-in	ANP	Type1
Medicago truncatula	TKL	LYR4	G7K7K0_MEDTR	LysM-domain receptor-like kinase	8PS7B	2.1	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Medicago truncatula	TKL	LYR4	G7K7K0_MEDTR	LysM-domain receptor-like kinase	8PS7A	2.1	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Methanocaldococcus jannaschii	OTHER	BUD32	KAE1B_METJA	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	2VWBA	3.05	Inactive	DFGin	None	in-in	in-none	ANP	Allosteric
Methanocaldococcus jannaschii	OTHER	BUD32	KAE1B_METJA	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	2VWBB	3.05	Inactive	DFGin	None	in-in	in-none	ANP	Allosteric
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM6C	2.39	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM6E	2.39	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM7A	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM7D	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM8C	1.85	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKND	2.75	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKOE	2.89	Inactive	DFGin	ABAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	8UKPE	2.85	Inactive	DFGin	ABAminus	in-out	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E11A	3.43	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	6MM5E	1.95	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3PVBA	3.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	2QCSA	2.2	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3IDBA	1.62	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3IDCA	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DG0E	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DH7A	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DH8A	2.3	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4HPTE	2.15	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4HPUE	1.55	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DFXE	1.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4XW4A	1.82	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E0ZA	2.162	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	7E12A	2.796	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	4DG3E	1.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3O7LB	2.8	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	3FHIA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	AGC	RPS6KA3	KS6A3_MOUSE	Ribosomal protein S6 kinase alpha-3	3G51A	1.8	Inactive	DFGin	None	none-none	out-none	ANP	Type1
Mus musculus	CAMK	CAMK2A	KCC2A_MOUSE	Calcium/calmodulin-dependent protein kinase type II subunit alpha	7B56B	1.45	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	CAMK	MELK	MELK_MOUSE	Maternal embryonic leucine zipper kinase	4BFMA	2.35	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Mus musculus	OTHER	POMK	SG196_MOUSE	Protein O-mannose kinase	5GZ9A	2.4	Inactive	DFGin	ABAminus	none-none	in-out	ANP MAN	Type1 Allosteric
Mus musculus	STE	STK39	STK39_MOUSE	STE20/SPS1-related proline-alanine-rich protein kinase	5DBXA	2.5	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Mus musculus	STE	STK39	STK39_MOUSE	STE20/SPS1-related proline-alanine-rich protein kinase	5DBXB	2.5	Inactive	DFGin	None	out-out	out-out	ANP	Type1
Mus musculus	TKL	RIPK3	RIPK3_MOUSE	Receptor-interacting serine/threonine-protein kinase 3	4M69A	2.497	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Mus musculus	TYR	EPHB2	EPHB2_MOUSE	Ephrin type-B receptor 2	1JPAA	1.91	Inactive	DFGin	None	in-in	none-none	ANP	Type1
Mus musculus	TYR	EPHB2	EPHB2_MOUSE	Ephrin type-B receptor 2	1JPAB	1.91	Inactive	DFGin	None	in-in	none-none	ANP	Type1
Mus musculus	TYR	LYN	LYN_MOUSE	Tyrosine-protein kinase Lyn	2ZV8A	2.7	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Neurospora crassa	OTHER	PAN3	PAN3_NEUCR	PAN2-PAN3 deadenylation complex subunit pan3	4CZYB	3.4	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Neurospora crassa	OTHER	PAN3	PAN3_NEUCR	PAN2-PAN3 deadenylation complex subunit pan3	4CZYD	3.4	Inactive	DFGin	None	out-none	out-none	ANP	Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUWC	2.88	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JURC	2.82	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type1
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUTC	3.09	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EW	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUUC	3.19	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUVC	3.36	Inactive	DFGin	BLBplus	out-out	out-out	ANP VKG	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUXC	3.34	Inactive	DFGin	BLBplus	out-out	out-out	ANP QOM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUYC	3.096	Inactive	DFGin	BLBplus	out-out	out-out	ANP EUI	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUZC	3.21	Inactive	DFGin	BLBplus	out-out	out-out	ANP 3EW	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JV0C	3.63	Inactive	DFGin	BLBplus	out-out	out-out	ANP 4BM	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JV1C	3.62	Inactive	DFGin	BLBplus	out-out	out-out	ANP VKG	Type1 Type3
Oryctolagus cuniculus	STE	MAP2K1	MP2K1_RABIT	Dual specificity mitogen-activated protein kinase kinase 1	7JUSC	2.99	Inactive	DFGin	BLBplus	out-out	out-out	VKD ANP	Type3 Type1
Pediculus humanus	OTHER	PINK1	PINK1_PEDHC	Serine/threonine-protein kinase Pink1, mitochondrial	8UYHA	2.84	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Pediculus humanus	OTHER	PINK1	PINK1_PEDHC	Serine/threonine-protein kinase Pink1, mitochondrial	8UYHB	2.84	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium berghei	CAMK	CDPK1	CDPK1_PLABA	Calcium-dependent protein kinase 1	3Q5IA	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium falciparum	CMGC	MAPK	Q7KQK7_PLAF7	Mitogen-activated protein kinase	3NIEA	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Plasmodium falciparum	CMGC	MAPK	Q7KQK7_PLAF7	Mitogen-activated protein kinase	3NIEB	2.3	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Plasmodium falciparum	CMGC	PSTK1	Q8IL19_PLAF7	Protein serine/threonine kinase-1	3LLTA	2.5	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Plasmodium falciparum	OTHER	PK7	O96214_PLAFA	mitogen-activated protein kinase kinase	2PMLX	2.6	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Plasmodium vivax	AGC	PKG	KGP_PLAVS	cGMP-dependent protein kinase	5DZCA	2.3	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Rattus norvegicus	AGC	PRKCB	KPCB_RAT	Protein kinase C beta type	3PFQA	4.0	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S33A	1.48	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S32A	1.34	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	7UGBA	1.9	Inactive	DFGin	BLAminus	in-in	in-out	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	4S34A	2.5	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQVA	2.19	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQXA	1.7	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	CMGC	MAPK1	MK01_RAT	Mitogen-activated protein kinase 1	8RQWA	1.8	Inactive	DFGin	BLAminus	in-out	in-in	ANP	Type1
Rattus norvegicus	OTHER	WNK1	WNK1_RAT	Serine/threonine-protein kinase WNK1	5W7TA	2.01	Inactive	DFGin	BLBtrans	out-none	out-in	ANP	Type1
Rattus norvegicus	OTHER	WNK1	WNK1_RAT	Serine/threonine-protein kinase WNK1	5W7TB	2.01	Inactive	DFGin	BLBtrans	out-none	out-in	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQSA	3.3	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	5NCLA	3.15	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQPA	4.5	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	AGC	CBK1	CBK1_YEAST	Serine/threonine-protein kinase CBK1	4LQQA	3.6	Inactive	None	None	none-none	out-out	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	4PDSA	2.9	None	DFGin	BLAminus	in-none	in-none	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	4PDSB	2.9	None	DFGin	BLAminus	in-none	in-none	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	5XZVB	3.1	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Saccharomyces cerevisiae	CAMK	RAD53	RAD53_YEAST	Serine/threonine-protein kinase RAD53	5XZVA	3.1	Inactive	DFGin	None	in-out	out-none	ANP	Type1
Saccharomyces cerevisiae	CMGC	CKA1	CSK21_YEAST	Casein kinase II subunit alpha	4JQEA	1.77	Inactive	None	None	out-none	in-in	ANP	Type1
Saccharomyces cerevisiae	CMGC	SKY1	SKY1_YEAST	Serine/threonine-protein kinase SKY1	1Q99A	2.11	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Saccharomyces cerevisiae	CMGC	SKY1	SKY1_YEAST	Serine/threonine-protein kinase SKY1	1Q99B	2.11	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Saccharomyces cerevisiae	OTHER	BUD32	BUD32_YEAST	EKC/KEOPS complex subunit BUD32	4WW5A	1.997	Active	DFGin	BLAminus	in-in	in-none	ANP	Type1.5_Front
Saccharomyces cerevisiae	OTHER	GCN2	GCN2_YEAST	eIF-2-alpha kinase GCN2	1ZY5A	2.0	Inactive	DFGin	BLBminus	out-out	out-none	ANP	Type1
Saccharomyces cerevisiae	OTHER	GCN2	GCN2_YEAST	eIF-2-alpha kinase GCN2	1ZY5B	2.0	Inactive	DFGin	BLBminus	out-out	none-out	ANP	Type1
Sus scrofa	AGC	PRKACA	KAPCA_PIG	cAMP-dependent protein kinase catalytic subunit alpha	1CDKA	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Sus scrofa	AGC	PRKACA	KAPCA_PIG	cAMP-dependent protein kinase catalytic subunit alpha	1CDKB	2.0	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PA	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PB	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PC	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Sus scrofa	OTHER	RNASEL	A5H025_PIG	Ribonuclease L	4O1PD	2.5	Inactive	DFGin	ABAminus	in-in	in-none	ANP 25L	Type1 Allosteric
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	4IEBA	2.05	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	3HX4A	1.95	Inactive	DFGin	BLAminus	out-out	in-in	ANP	Type1
Toxoplasma gondii	CAMK	CDPK1	Q9BJF5_TOXGO	non-specific serine/threonine protein kinase	3KU2A	2.3	Inactive	None	None	out-none	out-out	ANP	Type1
Tribolium castaneum	OTHER	PINK1	PINK1_TRICA	Serine/threonine-protein kinase Pink1, mitochondrial	5YJ9D	2.53	Inactive	DFGin	ABAminus	in-in	in-in	ANP	Type1
Trichomonas vaginalis	CMGC	TVAG125560	A2F9N1_TRIV3	non-specific serine/threonine protein kinase	9AV7A	2.1	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Xenopus laevis	CAMK	AURKBA	AUKBA_XENLA	Aurora kinase B-A	4C2WA	1.7	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Xenopus laevis	CAMK	AURKBA	AUKBA_XENLA	Aurora kinase B-A	4C2WB	1.7	Inactive	DFGin	ABAminus	out-out	in-in	ANP	Type1
Zea mays	CMGC	ACK2	CSK2A_MAIZE	Casein kinase II subunit alpha	1DAWA	2.2	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Zea mays	CMGC	ACK2	CSK2A_MAIZE	Casein kinase II subunit alpha	1LP4A	1.86	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1
Zea mays	OTHER	SIRK1	K7VIQ3_MAIZE	Putative leucine-rich repeat protein kinase family protein	5UV4A	2.3	Inactive	DFGin	BLBplus	out-out	out-out	ANP	Type1

Protein kinases in complex with ANP

Total number of genes: 76

Total number of chains: 378

All chains

All chains - renumbered by

Protein kinases in complex with ANP

Total number of genes: 117

Total number of chains: 513

All chains

All chains - renumbered by

Protein kinases in complex with ANP

Total number of genes: 46

Total number of chains: 135

All chains

All chains - renumbered by