Protein kinases with DFGout - None conformation

Total number of genes: 69
Total number of chains: 312
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGout None 28 11 0 39 13 0 58 26 124 13 3G0EA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 5KCVA 2.7 none-none none-none 6S1 Allosteric
AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7APJA 2.05 none-none none-none No_ligand No_ligand
AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZKA 2.3 in-none none-none No_ligand No_ligand
AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZOA 2.75 in-none none-none No_ligand No_ligand
AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZNA 2.5 in-none none-none No_ligand No_ligand
AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1MRVA 2.8 none-none none-none No_ligand No_ligand
AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1MRYA 2.8 none-none none-out No_ligand No_ligand
PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3QC4B 1.8 out-out in-in MP7 Type2
ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25A 2.337 in-in none-out 86G Type1
ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25B 2.337 in-in none-out 86G Type1
ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25C 2.337 in-in none-none 86G Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8EQ5A 1.8 none-none out-out QCT Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8R58A 2.31 none-none out-out QCT Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYA 3.2 out-out out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYB 3.2 out-out out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYC 3.2 none-none out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYD 3.2 none-none out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYE 3.2 none-none out-in A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYF 3.2 none-none out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYG 3.2 in-out out-in A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYH 3.2 out-out out-in A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYI 3.2 none-none out-out A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYJ 3.2 none-none out-in A1LU8 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 4NUSA 2.39 in-out out-in 2NK Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9LA 2.15 in-out out-out 583 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9KA 2.55 in-out out-in 584 Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9KB 2.55 in-none out-in 584 Type1
SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 7PUEA 2.506 none-none out-out 86H Type1
AURKA AURKA_HUMAN Aurora kinase A 6VPJA 2.1 out-out out-out ANP Type1
AURKA AURKA_HUMAN Aurora kinase A 4JAIA 3.2 out-out none-none XU2 Type1
AURKA AURKA_HUMAN Aurora kinase A 7AYHA 2.8 out-out none-none S9H Type1
AURKA AURKA_HUMAN Aurora kinase A 6VPHA 2.14 out-out out-out ANP Type1
AURKA AURKA_HUMAN Aurora kinase A 7O2VA 3.1 out-out out-out V0K Type1
AURKA AURKA_HUMAN Aurora kinase A 3O51A 3.2 out-none none-none LJF Type1.5_Front
AURKA AURKA_HUMAN Aurora kinase A 6HJKA 2.4 out-none out-out G7W Type1.5_Front
MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5K00A 1.77 out-in out-none 6PV Type2
MKNK1 MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 5WVDA 3.0 in-out out-none 7UX Type1
MKNK1 MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 5WVDB 3.0 in-out out-none 7UX Type1
MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 6JLRA 2.901 in-in out-out BV9 Type1
CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 3MTLA 2.4 in-in out-none FEF Type1
CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VB 2.2 in-in out-out 919 Type2
CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5A14A 2.0 in-in out-out LQ5 LQ5 Type2 Allosteric
CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 9EZ3A 2.7 in-in none-in A1H74 Type2
MAPK11 MK11_HUMAN Mitogen-activated protein kinase 11 8YGWA 3.301 in-out none-out B96 Type2
MAPK13 MK13_HUMAN Mitogen-activated protein kinase 13 5EKNA 2.594 in-in none-out N58 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N64A 2.4 in-in none-out 8OH Allosteric
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N66A 2.4 in-in none-out BW1 B96 Allosteric Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A 2.2 in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2FSMX 1.86 in-in none-out No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2NPQA 1.8 in-in none-out No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4GEOA 1.66 in-in none-none No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MH3A 2.2 in-in none-out No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MH1A 2.2 in-out none-out No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3IW5A 2.5 in-out none-out DF3 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3L8SA 2.35 in-in none-out BFF Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6SFKA 1.8 in-in none-out LB8 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HECA 2.5 in-in none-out STI Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNUA 2.4 in-in out-out EDB Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNWA 1.89 in-in out-out EDD Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV2A 2.8 in-in none-none B96 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBSA 1.8 in-in out-out LI2 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBTA 2.0 in-in out-out WBT Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ1A 1.8 in-in none-out NIL Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3UVRA 2.1 in-in none-out 06F Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4L8MA 2.1 in-in out-out F46 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3BV3A 2.59 in-in none-out P39 Type2
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YISA 2.0 in-in none-out YIS I46 Type2 Allosteric
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YIWA 2.0 in-in none-out YIW I46 Type2 Allosteric
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ5A 3.3 in-in none-out A1AWV PDO Type2 Allosteric
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3JA 1.995 in-in none-out F4C I46 Type2 Allosteric
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFDA 3.4 in-in none-out Z85 Type3
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV1A 2.5 in-in none-out BMU Type3
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8TA 2.0 in-out none-out BMU Type3
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OC1A 2.59 in-in none-out BMU Type3
MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCA 2.43 in-out out-out OXW Type1
MAPK9 MK09_HUMAN Mitogen-activated protein kinase 9 3NPCA 2.35 in-in out-out B96 Type2
MAPK9 MK09_HUMAN Mitogen-activated protein kinase 9 3NPCB 2.35 in-in out-out B96 Type2
PRP4K PRP4K_HUMAN Serine/threonine-protein kinase PRP4 homolog 6CNHA 2.0 in-in none-out 919 Type2
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK3A 2.2 out-out none-out XK3 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK4A 2.1 out-out none-out OL2 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK8A 2.001 out-out none-out 5R1 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNPA 1.98 out-out none-out WCX Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4AFEA 2.597 out-out none-out GGY Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4A4XA 2.4 out-out none-out JUP Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2A 2.78 out-out none-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75D 3.3 out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8WS0A 2.12 out-out out-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNA 4.04 out-none out-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNB 4.04 out-none out-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8WS1A 2.4 out-out out-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75A 3.3 out-none none-none F9N Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7HA 2.0 out-out none-none 3Z2 Type2
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKA 2.3 out-none none-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKB 2.3 out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKC 2.3 out-out out-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKD 2.3 out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKE 2.3 out-none none-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKG 2.3 out-out out-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LA 2.61 in-in none-none KAV Type2
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LB 2.61 in-in none-none KAV Type2
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A 2.463 out-out none-out 4K7 Type3
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B 2.463 out-out none-none 4K7 Type3
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C 2.463 out-out none-none 4K7 Type3
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZB 2.285 in-out none-out LN4 Type2
MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5HZEA 2.4 out-out none-out E62 Type1
MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8YP4B 2.35 out-out out-none WNT Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8P7JA 2.4 in-out out-none X3K Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8P7JB 2.4 out-out out-none X3K Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3A 2.0 out-out out-none ZLE Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3B 2.0 out-out out-none ZLE Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3C 2.0 out-out out-none ZLE Type1
MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3D 2.0 out-out out-none ZLE Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YZ4A 1.7 in-out out-out 1E8 Allosteric
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Y8UA 2.92 out-out none-out No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Y90A 1.3 in-out out-in No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5B2LA 2.1 in-out out-in No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YFZA 1.9 in-out out-out No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6QFRA 2.3 in-none out-none No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5B2KA 2.75 out-out none-out No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG0A 2.0 in-in out-none No_ligand No_ligand
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 7CBXA 2.061 in-out out-none FU6 Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Z1EA 2.3 in-out out-in 95U Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG4A 2.3 in-out out-none SU9 Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG5A 2.4 in-none out-none IHH Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 3WZUA 3.01 none-none none-out 1FM Type1
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG6A 2.15 out-out none-out OQ8 Type2
MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG6B 2.15 out-out none-out OQ8 Type2
MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 8QGYA 3.71 in-out in-none No_ligand No_ligand
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PAUA 2.8 out-out none-out XOR Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PAUB 2.8 out-out none-out XOR Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PASA 2.7 out-out none-none XOH Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PASB 2.7 out-out out-none XOH Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8CDWA 1.941 out-out out-out UES Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8CIJA 2.821 out-out none-in USF Type1
MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PARA 2.0 out-out none-out XON Type1
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZB 2.09 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4ZP5B 2.29 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5DI1B 2.9 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5J95B 2.5 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 8V5IB 2.18 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4RVTB 2.4 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBOB 2.1 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBPB 2.27 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBQB 2.19 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U40B 2.3 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U41B 2.2 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U43B 2.18 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U44B 2.43 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U45B 2.58 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4ZK5B 2.89 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5W5QB 2.33 out-out out-out No_ligand No_ligand
PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZLOA 2.5 out-out none-out 4PV Type3
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4AOTA 2.33 out-out out-out GW8 Type1
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4AOTB 2.33 out-out out-out GW8 Type1
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4USDA 3.05 out-out none-out R09 Type1
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4USDB 3.05 out-out none-out R09 Type1
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4EQUA 2.0 in-in out-out G6I Type2
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4EQUB 2.0 in-in out-out G6I Type2
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YA 2.56 out-out in-out 88Z Type2
STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YB 2.56 out-none out-out 88Z Type2
STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZAB 3.15 out-out out-out No_ligand No_ligand
STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZDB 3.25 out-out out-out No_ligand No_ligand
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZWA 3.493 in-in none-out B1E Type1
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3C4CB 2.57 in-out none-out 324 Type1.5_Back
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZWB 3.493 in-in none-out B1E Type2
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6CADB 2.55 in-in none-out EU4 Type2
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6NSQB 3.05 in-in none-out KZP Type2
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8QQGA 2.979 in-in out-out WJ9 Type2
BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CT7B 3.17 in-in none-out 55J Type2
IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EG9A 2.414 in-out none-in 0LI Type2
IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EG9B 2.414 in-in none-in 0LI Type2
IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAA 2.512 in-in none-in J8A Type2
IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAB 2.512 in-in none-in J8A Type2
LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDA 1.9 out-out out-none 9D8 Type3
LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E04A 3.8 in-in none-none No_ligand No_ligand
LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E05A 4.6 in-in none-none No_ligand No_ligand
LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E05B 4.6 in-in none-none No_ligand No_ligand
LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E06A 4.3 in-out none-none No_ligand No_ligand
LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8FACA 3.92 in-out out-none No_ligand No_ligand
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9E 3.48 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8TZEA 2.9 in-in none-none T3X Type2
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8TZFA 3.4 in-in none-none T3X Type2
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J9LA 2.752 in-out none-out 6HF Type1
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J7SA 2.368 out-out none-out 6H3 Type1
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5GJFA 2.89 in-in out-out 6V4 Type2
RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 4C8BA 2.75 in-in none-out 0LI Type2
RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 4C8BB 2.75 in-in none-out 0LI Type2
RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR7A 2.71 in-in out-none SR8 Type2
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6XR7A 999.0 in-in out-in No_ligand No_ligand
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7TB 2.8 in-in out-in 6I5 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZIA 1.7 in-in out-in JIN Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGB 2.3 in-in out-in VX6 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9B 2.2 in-in out-in AXI Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3UE4A 2.424 in-out out-in DB8 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3UE4B 2.424 in-out out-in DB8 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FB 2.7 in-in out-in AGS Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7TA 2.8 in-in out-in 6I5 Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZIB 1.7 in-in out-in JIN Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HB 2.0 in-out out-in P16 Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2FO0A 2.27 in-in out-in P16 Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 1OPLA 3.42 in-in out-in P16 Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 1OPLB 3.42 in-in out-in P16 Type1.5_Back
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A 2.17 in-in none-out NIL AY7 Type2 Allosteric
ALK ALK_HUMAN ALK tyrosine kinase receptor 4FNYA 2.45 in-in none-out I3K Type2
CSF1R CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor 2OGVA 2.7 in-out out-in No_ligand No_ligand
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVWA 1.94 in-in none-in 1N1 Type1
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5SB2A 1.6 in-in out-in 1K2 Type2
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVKA 2.29 in-in out-in 4VC Type3
EGFR EGFR_HUMAN Epidermal growth factor receptor 4I1ZA 3.0 out-out in-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 4I21A 3.37 out-out in-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 4I21B 3.37 out-out in-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 2RF9B 3.5 out-none in-out No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 4I20A 3.34 out-out in-in No_ligand No_ligand
EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA4A 1.797 in-out out-in 88Z Type2
EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA5A 1.776 in-out out-in GV0 Type2
EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 6Q7FA 1.204 in-in none-none HNZ Type2
EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 8BOFA 1.82 in-in none-none R3L Type2
EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 4P5ZA 2.002 in-in none-none Q7M Type2
EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 4TWNA 1.706 in-in out-in B96 Type2
ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 8U8XA 1.69 out-out out-out W9N Type1
FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V01A 2.33 in-in none-out 0LI Type2
FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V01B 2.33 in-in none-out 0LI Type2
FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V04A 2.12 in-in none-out 0LI Type2
FGFR4 FGFR4_HUMAN Fibroblast growth factor receptor 4 4QRCA 1.901 in-in out-out 0LI Type2
FGR FGR_HUMAN Tyrosine-protein kinase Fgr 7UY3A 2.99 in-in out-in OJL Type2
FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 1RJBA 2.1 in-in out-in No_ligand No_ligand
FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 6JQRA 2.2 in-in none-in C6F Type1
FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 8XB1A 2.85 in-in none-in ZX3 Type1
FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 5X02A 2.401 in-in out-in F6M Type1
FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 6IL3A 2.5 in-in out-in A9R Type1
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3O23A 2.1 out-out out-in MQY Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYJAAA 2.702 in-out out-in IEA Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYKAAA 2.23 out-out out-in IC2 Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYLAAA 2.93 out-out out-in IE0 Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYMAAA 2.652 out-out out-in IED Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYNAAA 1.71 in-out out-in ICV Type2
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D 1.79 in-out out-in CCX CCX Type3 Allosteric
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3C7QA 2.1 in-in none-out XIN Type1
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 2P2IB 2.4 in-in none-none 608 Type1
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VNTA 1.64 in-in out-in 0JA Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VO3A 1.52 in-in out-in 0KF Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 2QU6B 2.1 in-in none-out 857 Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3B8QA 2.75 in-in none-out 900 Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3CPBA 2.7 in-in none-out C92 Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3CPCA 2.4 in-out none-out C52 Type2
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3DTWA 2.9 in-in none-out A96 Type2
KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1T45A 1.9 in-in out-in No_ligand No_ligand
KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 3G0EA 1.6 in-in out-in B49 Type1
LCK LCK_HUMAN Tyrosine-protein kinase Lck 2OFVA 2.0 in-in none-none 242 Type2
LCK LCK_HUMAN Tyrosine-protein kinase Lck 2OFVB 2.0 in-in out-none 242 Type2
MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AVXB 2.44 out-out none-none S4K Type1
MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AAXA 1.762 out-out none-none R6H Type2
MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW1A 1.98 out-out none-none S4T Type2
MET MET_HUMAN Hepatocyte growth factor receptor 3RHKA 1.94 out-out out-in M97 Type1
MET MET_HUMAN Hepatocyte growth factor receptor 3EFJA 2.6 out-out none-none MT3 Type1.5_Front
MET MET_HUMAN Hepatocyte growth factor receptor 5DG5A 2.6 in-out out-in 5B4 Type2
MET MET_HUMAN Hepatocyte growth factor receptor 5DG5B 2.6 in-out out-in 5B4 Type2
MET MET_HUMAN Hepatocyte growth factor receptor 7V3RA 1.7 in-out out-in 5IE Type2
MET MET_HUMAN Hepatocyte growth factor receptor 3CTJA 2.5 in-in none-in 320 Type2
MET MET_HUMAN Hepatocyte growth factor receptor 3C1XA 2.17 in-out none-in CKK Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A 1.94 out-out out-in FQD FQG Allosteric Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4F0IA 2.302 out-out out-in No_ligand No_ligand
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4F0IB 2.302 in-out out-in No_ligand No_ligand
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4GT5A 2.398 in-none out-in No_ligand No_ligand
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D22A 2.46 in-out out-in No_ligand No_ligand
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKBA 2.68 out-in none-in FKY Type1
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMOA 2.67 out-out out-in 6UM Type1
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4PMSA 2.8 in-out out-in 31X Type1.5_Back
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J5WA 2.28 in-out out-in A4U Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J61A 3.051 out-out out-in A0X Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J63A 3.001 in-out out-in A6X Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5WR7A 2.76 out-out out-in RCH Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL1A 2.03 in-out out-in OOJ Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL3A 3.0 in-out out-in OOD Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMAA 2.53 in-in out-in OQS Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMBA 2.81 in-in out-in OQM Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMCA 2.19 in-in out-in OQJ Type2
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSPA 2.31 in-out out-in L0P Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NPTA 2.19 out-out out-in KWY Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSSA 1.97 in-out out-in L0M Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1YA 1.93 out-out out-in FQJ Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMIA 1.87 in-out out-in 6UE Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMJA 2.04 in-in out-in 6UF Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMKA 2.24 in-out out-in 6UG Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMMA 2.12 in-out out-in 6UJ Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMLA 2.01 in-out out-in 6UH Type3
NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMNA 2.14 in-out out-in 6UK Type3
NTRK2 NTRK2_HUMAN BDNF/NT-3 growth factors receptor 4ASZA 1.7 in-out out-in No_ligand No_ligand
NTRK2 NTRK2_HUMAN BDNF/NT-3 growth factors receptor 4AT5A 1.71 in-out out-in MUJ Type2
NTRK3 NTRK3_HUMAN NT-3 growth factor receptor 4YMJA 2.0 out-out none-in 4EJ Type1
NTRK3 NTRK3_HUMAN NT-3 growth factor receptor 4YMJB 2.0 out-none out-in 4EJ Type1
PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 8PQKA 2.0 in-in out-in No_ligand No_ligand
PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 6A32A 1.87 in-in out-in No_ligand No_ligand
PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 8PQJA 1.82 in-in out-in No_ligand No_ligand
PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 5K5XA 2.168 in-in out-in No_ligand No_ligand
PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 6JOKA 3.8 in-out out-in B49 Type1
PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBVA 1.67 in-in none-out 0O7 Type1
PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K9YA 2.0 in-in out-out K9Y Type2
PTK2 FAK1_HUMAN Focal adhesion kinase 1 4I4FA 1.75 out-out none-out 1BR Type3
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3ET7A 2.7 in-in out-in 349 Type1
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZPA 2.1 in-out none-in AGS Type1
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZRA 2.7 in-in out-in 3JZ Type1
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 5TO8A 1.985 in-none out-none 7FM Type1
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZTA 1.95 in-in out-in 4JZ Type2
PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 4H1JA 2.0 in-in out-in 0YH Type2
ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWB 2.9 in-out out-in No_ligand No_ligand
SYK KSYK_HUMAN Tyrosine-protein kinase SYK 3TUDA 2.33 in-in none-in FPX Type2
TEK TIE2_HUMAN Angiopoietin-1 receptor 2WQBA 2.95 none-none out-out QQ1 Type1
TEK TIE2_HUMAN Angiopoietin-1 receptor 2P4IB 2.5 in-in none-out MR9 Type2
TEK TIE2_HUMAN Angiopoietin-1 receptor 4X3JA 2.5 in-out none-out 3WR Type2
TNK2 ACK1_HUMAN Activated CDC42 kinase 1 5ZXBA 2.198 in-in none-none 9KO Type2
TNK2 ACK1_HUMAN Activated CDC42 kinase 1 5ZXBB 2.198 in-in none-none 9KO Type2

All kinases with DFGout - None conformation

Total number of genes: 78
Total number of chains: 355
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGout None 31 11 0 46 13 0 58 32 136 28 4I93A
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I92A 1.6 out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93A 1.5 out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93B 1.5 out-out out-none No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94A 1.8 out-out out-out ANP Type1
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94B 1.8 out-out out-out ANP Type1
Arabidopsis thaliana CTR1 CTR1_ARATH Serine/threonine-protein kinase CTR1 3P86A 2.496 out-out none-out STU Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3D7TB 2.899 in-in out-in STU Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5K9IB 2.5 out-out in-in O44 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OB 2.69 out-out none-out TZ0 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3EL7A 2.8 in-in none-none PD3 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3EL8A 2.3 in-in in-out PD5 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3G6GB 2.31 in-in none-out G6G Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4AGWA 2.6 in-in none-none NG7 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4AGWB 2.6 in-in none-none NG7 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3TZ9B 3.1 in-in none-out AQU Type2
Homo sapiens AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 5KCVA 2.7 none-none none-none 6S1 Allosteric
Homo sapiens AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7APJA 2.05 none-none none-none No_ligand No_ligand
Homo sapiens AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZKA 2.3 in-none none-none No_ligand No_ligand
Homo sapiens AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZOA 2.75 in-none none-none No_ligand No_ligand
Homo sapiens AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1GZNA 2.5 in-none none-none No_ligand No_ligand
Homo sapiens AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1MRVA 2.8 none-none none-none No_ligand No_ligand
Homo sapiens AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 1MRYA 2.8 none-none none-out No_ligand No_ligand
Homo sapiens PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3QC4B 1.8 out-out in-in MP7 Type2
Homo sapiens ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25A 2.337 in-in none-out 86G Type1
Homo sapiens ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25B 2.337 in-in none-out 86G Type1
Homo sapiens ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S25C 2.337 in-in none-none 86G Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8EQ5A 1.8 none-none out-out QCT Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8R58A 2.31 none-none out-out QCT Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYA 3.2 out-out out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYB 3.2 out-out out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYC 3.2 none-none out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYD 3.2 none-none out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYE 3.2 none-none out-in A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYF 3.2 none-none out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYG 3.2 in-out out-in A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYH 3.2 out-out out-in A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYI 3.2 none-none out-out A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 8XFYJ 3.2 none-none out-in A1LU8 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 4NUSA 2.39 in-out out-in 2NK Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9LA 2.15 in-out out-out 583 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9KA 2.55 in-out out-in 584 Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 5D9KB 2.55 in-none out-in 584 Type1
Homo sapiens SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 7PUEA 2.506 none-none out-out 86H Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6VPJA 2.1 out-out out-out ANP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4JAIA 3.2 out-out none-none XU2 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 7AYHA 2.8 out-out none-none S9H Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6VPHA 2.14 out-out out-out ANP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 7O2VA 3.1 out-out out-out V0K Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3O51A 3.2 out-none none-none LJF Type1.5_Front
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6HJKA 2.4 out-none out-out G7W Type1.5_Front
Homo sapiens MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5K00A 1.77 out-in out-none 6PV Type2
Homo sapiens MKNK1 MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 5WVDA 3.0 in-out out-none 7UX Type1
Homo sapiens MKNK1 MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 5WVDB 3.0 in-out out-none 7UX Type1
Homo sapiens MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 6JLRA 2.901 in-in out-out BV9 Type1
Homo sapiens CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 3MTLA 2.4 in-in out-none FEF Type1
Homo sapiens CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VB 2.2 in-in out-out 919 Type2
Homo sapiens CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5A14A 2.0 in-in out-out LQ5 LQ5 Type2 Allosteric
Homo sapiens CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 9EZ3A 2.7 in-in none-in A1H74 Type2
Homo sapiens MAPK11 MK11_HUMAN Mitogen-activated protein kinase 11 8YGWA 3.301 in-out none-out B96 Type2
Homo sapiens MAPK13 MK13_HUMAN Mitogen-activated protein kinase 13 5EKNA 2.594 in-in none-out N58 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N64A 2.4 in-in none-out 8OH Allosteric
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N66A 2.4 in-in none-out BW1 B96 Allosteric Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A 2.2 in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2FSMX 1.86 in-in none-out No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2NPQA 1.8 in-in none-out No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4GEOA 1.66 in-in none-none No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MH3A 2.2 in-in none-out No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MH1A 2.2 in-out none-out No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3IW5A 2.5 in-out none-out DF3 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3L8SA 2.35 in-in none-out BFF Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6SFKA 1.8 in-in none-out LB8 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HECA 2.5 in-in none-out STI Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNUA 2.4 in-in out-out EDB Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNWA 1.89 in-in out-out EDD Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV2A 2.8 in-in none-none B96 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBSA 1.8 in-in out-out LI2 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBTA 2.0 in-in out-out WBT Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ1A 1.8 in-in none-out NIL Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3UVRA 2.1 in-in none-out 06F Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4L8MA 2.1 in-in out-out F46 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3BV3A 2.59 in-in none-out P39 Type2
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YISA 2.0 in-in none-out YIS I46 Type2 Allosteric
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YIWA 2.0 in-in none-out YIW I46 Type2 Allosteric
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ5A 3.3 in-in none-out A1AWV PDO Type2 Allosteric
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3JA 1.995 in-in none-out F4C I46 Type2 Allosteric
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFDA 3.4 in-in none-out Z85 Type3
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV1A 2.5 in-in none-out BMU Type3
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8TA 2.0 in-out none-out BMU Type3
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OC1A 2.59 in-in none-out BMU Type3
Homo sapiens MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCA 2.43 in-out out-out OXW Type1
Homo sapiens MAPK9 MK09_HUMAN Mitogen-activated protein kinase 9 3NPCA 2.35 in-in out-out B96 Type2
Homo sapiens MAPK9 MK09_HUMAN Mitogen-activated protein kinase 9 3NPCB 2.35 in-in out-out B96 Type2
Homo sapiens PRP4K PRP4K_HUMAN Serine/threonine-protein kinase PRP4 homolog 6CNHA 2.0 in-in none-out 919 Type2
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK3A 2.2 out-out none-out XK3 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK4A 2.1 out-out none-out OL2 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK8A 2.001 out-out none-out 5R1 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNPA 1.98 out-out none-out WCX Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4AFEA 2.597 out-out none-out GGY Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4A4XA 2.4 out-out none-out JUP Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2A 2.78 out-out none-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75D 3.3 out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8WS0A 2.12 out-out out-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNA 4.04 out-none out-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNB 4.04 out-none out-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8WS1A 2.4 out-out out-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75A 3.3 out-none none-none F9N Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7HA 2.0 out-out none-none 3Z2 Type2
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKA 2.3 out-none none-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKB 2.3 out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKC 2.3 out-out out-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKD 2.3 out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKE 2.3 out-none none-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKG 2.3 out-out out-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LA 2.61 in-in none-none KAV Type2
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LB 2.61 in-in none-none KAV Type2
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A 2.463 out-out none-out 4K7 Type3
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B 2.463 out-out none-none 4K7 Type3
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C 2.463 out-out none-none 4K7 Type3
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZB 2.285 in-out none-out LN4 Type2
Homo sapiens MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5HZEA 2.4 out-out none-out E62 Type1
Homo sapiens MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8YP4B 2.35 out-out out-none WNT Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8P7JA 2.4 in-out out-none X3K Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8P7JB 2.4 out-out out-none X3K Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3A 2.0 out-out out-none ZLE Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3B 2.0 out-out out-none ZLE Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3C 2.0 out-out out-none ZLE Type1
Homo sapiens MAP2K6 MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 8PM3D 2.0 out-out out-none ZLE Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YZ4A 1.7 in-out out-out 1E8 Allosteric
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Y8UA 2.92 out-out none-out No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Y90A 1.3 in-out out-in No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5B2LA 2.1 in-out out-in No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YFZA 1.9 in-out out-out No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6QFRA 2.3 in-none out-none No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5B2KA 2.75 out-out none-out No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG0A 2.0 in-in out-none No_ligand No_ligand
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 7CBXA 2.061 in-out out-none FU6 Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 5Z1EA 2.3 in-out out-in 95U Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG4A 2.3 in-out out-none SU9 Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG5A 2.4 in-none out-none IHH Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 3WZUA 3.01 none-none none-out 1FM Type1
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG6A 2.15 out-out none-out OQ8 Type2
Homo sapiens MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG6B 2.15 out-out none-out OQ8 Type2
Homo sapiens MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 8QGYA 3.71 in-out in-none No_ligand No_ligand
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PAUA 2.8 out-out none-out XOR Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PAUB 2.8 out-out none-out XOR Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PASA 2.7 out-out none-none XOH Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PASB 2.7 out-out out-none XOH Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8CDWA 1.941 out-out out-out UES Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8CIJA 2.821 out-out none-in USF Type1
Homo sapiens MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 8PARA 2.0 out-out none-out XON Type1
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZB 2.09 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4ZP5B 2.29 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5DI1B 2.9 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5J95B 2.5 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 8V5IB 2.18 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4RVTB 2.4 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBOB 2.1 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBPB 2.27 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4OBQB 2.19 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U40B 2.3 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U41B 2.2 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U43B 2.18 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U44B 2.43 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U45B 2.58 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4ZK5B 2.89 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 5W5QB 2.33 out-out out-out No_ligand No_ligand
Homo sapiens PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZLOA 2.5 out-out none-out 4PV Type3
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4AOTA 2.33 out-out out-out GW8 Type1
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4AOTB 2.33 out-out out-out GW8 Type1
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4USDA 3.05 out-out none-out R09 Type1
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4USDB 3.05 out-out none-out R09 Type1
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4EQUA 2.0 in-in out-out G6I Type2
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 4EQUB 2.0 in-in out-out G6I Type2
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YA 2.56 out-out in-out 88Z Type2
Homo sapiens STK10 STK10_HUMAN Serine/threonine-protein kinase 10 6I2YB 2.56 out-none out-out 88Z Type2
Homo sapiens STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZAB 3.15 out-out out-out No_ligand No_ligand
Homo sapiens STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZDB 3.25 out-out out-out No_ligand No_ligand
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZWA 3.493 in-in none-out B1E Type1
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3C4CB 2.57 in-out none-out 324 Type1.5_Back
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZWB 3.493 in-in none-out B1E Type2
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6CADB 2.55 in-in none-out EU4 Type2
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6NSQB 3.05 in-in none-out KZP Type2
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8QQGA 2.979 in-in out-out WJ9 Type2
Homo sapiens BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CT7B 3.17 in-in none-out 55J Type2
Homo sapiens IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EG9A 2.414 in-out none-in 0LI Type2
Homo sapiens IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EG9B 2.414 in-in none-in 0LI Type2
Homo sapiens IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAA 2.512 in-in none-in J8A Type2
Homo sapiens IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAB 2.512 in-in none-in J8A Type2
Homo sapiens LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDA 1.9 out-out out-none 9D8 Type3
Homo sapiens LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E04A 3.8 in-in none-none No_ligand No_ligand
Homo sapiens LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E05A 4.6 in-in none-none No_ligand No_ligand
Homo sapiens LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E05B 4.6 in-in none-none No_ligand No_ligand
Homo sapiens LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8E06A 4.3 in-out none-none No_ligand No_ligand
Homo sapiens LRRK1 LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 8FACA 3.92 in-out out-none No_ligand No_ligand
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9E 3.48 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8TZEA 2.9 in-in none-none T3X Type2
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8TZFA 3.4 in-in none-none T3X Type2
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J9LA 2.752 in-out none-out 6HF Type1
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J7SA 2.368 out-out none-out 6H3 Type1
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5GJFA 2.89 in-in out-out 6V4 Type2
Homo sapiens RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 4C8BA 2.75 in-in none-out 0LI Type2
Homo sapiens RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 4C8BB 2.75 in-in none-out 0LI Type2
Homo sapiens RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR7A 2.71 in-in out-none SR8 Type2
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6XR7A 999.0 in-in out-in No_ligand No_ligand
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7TB 2.8 in-in out-in 6I5 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZIA 1.7 in-in out-in JIN Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGB 2.3 in-in out-in VX6 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9B 2.2 in-in out-in AXI Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3UE4A 2.424 in-out out-in DB8 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3UE4B 2.424 in-out out-in DB8 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FB 2.7 in-in out-in AGS Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7TA 2.8 in-in out-in 6I5 Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZIB 1.7 in-in out-in JIN Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HB 2.0 in-out out-in P16 Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2FO0A 2.27 in-in out-in P16 Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 1OPLA 3.42 in-in out-in P16 Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 1OPLB 3.42 in-in out-in P16 Type1.5_Back
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A 2.17 in-in none-out NIL AY7 Type2 Allosteric
Homo sapiens ALK ALK_HUMAN ALK tyrosine kinase receptor 4FNYA 2.45 in-in none-out I3K Type2
Homo sapiens CSF1R CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor 2OGVA 2.7 in-out out-in No_ligand No_ligand
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVWA 1.94 in-in none-in 1N1 Type1
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5SB2A 1.6 in-in out-in 1K2 Type2
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVKA 2.29 in-in out-in 4VC Type3
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4I1ZA 3.0 out-out in-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4I21A 3.37 out-out in-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4I21B 3.37 out-out in-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 2RF9B 3.5 out-none in-out No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4I20A 3.34 out-out in-in No_ligand No_ligand
Homo sapiens EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA4A 1.797 in-out out-in 88Z Type2
Homo sapiens EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA5A 1.776 in-out out-in GV0 Type2
Homo sapiens EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 6Q7FA 1.204 in-in none-none HNZ Type2
Homo sapiens EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 8BOFA 1.82 in-in none-none R3L Type2
Homo sapiens EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 4P5ZA 2.002 in-in none-none Q7M Type2
Homo sapiens EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 4TWNA 1.706 in-in out-in B96 Type2
Homo sapiens ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 8U8XA 1.69 out-out out-out W9N Type1
Homo sapiens FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V01A 2.33 in-in none-out 0LI Type2
Homo sapiens FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V01B 2.33 in-in none-out 0LI Type2
Homo sapiens FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 4V04A 2.12 in-in none-out 0LI Type2
Homo sapiens FGFR4 FGFR4_HUMAN Fibroblast growth factor receptor 4 4QRCA 1.901 in-in out-out 0LI Type2
Homo sapiens FGR FGR_HUMAN Tyrosine-protein kinase Fgr 7UY3A 2.99 in-in out-in OJL Type2
Homo sapiens FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 1RJBA 2.1 in-in out-in No_ligand No_ligand
Homo sapiens FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 6JQRA 2.2 in-in none-in C6F Type1
Homo sapiens FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 8XB1A 2.85 in-in none-in ZX3 Type1
Homo sapiens FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 5X02A 2.401 in-in out-in F6M Type1
Homo sapiens FLT3 FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 6IL3A 2.5 in-in out-in A9R Type1
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3O23A 2.1 out-out out-in MQY Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYJAAA 2.702 in-out out-in IEA Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYKAAA 2.23 out-out out-in IC2 Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYLAAA 2.93 out-out out-in IE0 Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYMAAA 2.652 out-out out-in IED Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYNAAA 1.71 in-out out-in ICV Type2
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D 1.79 in-out out-in CCX CCX Type3 Allosteric
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3C7QA 2.1 in-in none-out XIN Type1
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 2P2IB 2.4 in-in none-none 608 Type1
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VNTA 1.64 in-in out-in 0JA Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VO3A 1.52 in-in out-in 0KF Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 2QU6B 2.1 in-in none-out 857 Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3B8QA 2.75 in-in none-out 900 Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3CPBA 2.7 in-in none-out C92 Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3CPCA 2.4 in-out none-out C52 Type2
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3DTWA 2.9 in-in none-out A96 Type2
Homo sapiens KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1T45A 1.9 in-in out-in No_ligand No_ligand
Homo sapiens KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 3G0EA 1.6 in-in out-in B49 Type1
Homo sapiens LCK LCK_HUMAN Tyrosine-protein kinase Lck 2OFVA 2.0 in-in none-none 242 Type2
Homo sapiens LCK LCK_HUMAN Tyrosine-protein kinase Lck 2OFVB 2.0 in-in out-none 242 Type2
Homo sapiens MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AVXB 2.44 out-out none-none S4K Type1
Homo sapiens MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AAXA 1.762 out-out none-none R6H Type2
Homo sapiens MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW1A 1.98 out-out none-none S4T Type2
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 3RHKA 1.94 out-out out-in M97 Type1
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 3EFJA 2.6 out-out none-none MT3 Type1.5_Front
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 5DG5A 2.6 in-out out-in 5B4 Type2
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 5DG5B 2.6 in-out out-in 5B4 Type2
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 7V3RA 1.7 in-out out-in 5IE Type2
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 3CTJA 2.5 in-in none-in 320 Type2
Homo sapiens MET MET_HUMAN Hepatocyte growth factor receptor 3C1XA 2.17 in-out none-in CKK Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A 1.94 out-out out-in FQD FQG Allosteric Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4F0IA 2.302 out-out out-in No_ligand No_ligand
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4F0IB 2.302 in-out out-in No_ligand No_ligand
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4GT5A 2.398 in-none out-in No_ligand No_ligand
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D22A 2.46 in-out out-in No_ligand No_ligand
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKBA 2.68 out-in none-in FKY Type1
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMOA 2.67 out-out out-in 6UM Type1
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 4PMSA 2.8 in-out out-in 31X Type1.5_Back
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J5WA 2.28 in-out out-in A4U Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J61A 3.051 out-out out-in A0X Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 8J63A 3.001 in-out out-in A6X Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5WR7A 2.76 out-out out-in RCH Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL1A 2.03 in-out out-in OOJ Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL3A 3.0 in-out out-in OOD Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMAA 2.53 in-in out-in OQS Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMBA 2.81 in-in out-in OQM Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PMCA 2.19 in-in out-in OQJ Type2
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSPA 2.31 in-out out-in L0P Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NPTA 2.19 out-out out-in KWY Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSSA 1.97 in-out out-in L0M Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1YA 1.93 out-out out-in FQJ Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMIA 1.87 in-out out-in 6UE Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMJA 2.04 in-in out-in 6UF Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMKA 2.24 in-out out-in 6UG Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMMA 2.12 in-out out-in 6UJ Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMLA 2.01 in-out out-in 6UH Type3
Homo sapiens NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMNA 2.14 in-out out-in 6UK Type3
Homo sapiens NTRK2 NTRK2_HUMAN BDNF/NT-3 growth factors receptor 4ASZA 1.7 in-out out-in No_ligand No_ligand
Homo sapiens NTRK2 NTRK2_HUMAN BDNF/NT-3 growth factors receptor 4AT5A 1.71 in-out out-in MUJ Type2
Homo sapiens NTRK3 NTRK3_HUMAN NT-3 growth factor receptor 4YMJA 2.0 out-out none-in 4EJ Type1
Homo sapiens NTRK3 NTRK3_HUMAN NT-3 growth factor receptor 4YMJB 2.0 out-none out-in 4EJ Type1
Homo sapiens PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 8PQKA 2.0 in-in out-in No_ligand No_ligand
Homo sapiens PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 6A32A 1.87 in-in out-in No_ligand No_ligand
Homo sapiens PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 8PQJA 1.82 in-in out-in No_ligand No_ligand
Homo sapiens PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 5K5XA 2.168 in-in out-in No_ligand No_ligand
Homo sapiens PDGFRA PGFRA_HUMAN Platelet-derived growth factor receptor alpha 6JOKA 3.8 in-out out-in B49 Type1
Homo sapiens PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBVA 1.67 in-in none-out 0O7 Type1
Homo sapiens PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K9YA 2.0 in-in out-out K9Y Type2
Homo sapiens PTK2 FAK1_HUMAN Focal adhesion kinase 1 4I4FA 1.75 out-out none-out 1BR Type3
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3ET7A 2.7 in-in out-in 349 Type1
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZPA 2.1 in-out none-in AGS Type1
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZRA 2.7 in-in out-in 3JZ Type1
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 5TO8A 1.985 in-none out-none 7FM Type1
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 3FZTA 1.95 in-in out-in 4JZ Type2
Homo sapiens PTK2B FAK2_HUMAN Protein-tyrosine kinase 2-beta 4H1JA 2.0 in-in out-in 0YH Type2
Homo sapiens ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWB 2.9 in-out out-in No_ligand No_ligand
Homo sapiens SYK KSYK_HUMAN Tyrosine-protein kinase SYK 3TUDA 2.33 in-in none-in FPX Type2
Homo sapiens TEK TIE2_HUMAN Angiopoietin-1 receptor 2WQBA 2.95 none-none out-out QQ1 Type1
Homo sapiens TEK TIE2_HUMAN Angiopoietin-1 receptor 2P4IB 2.5 in-in none-out MR9 Type2
Homo sapiens TEK TIE2_HUMAN Angiopoietin-1 receptor 4X3JA 2.5 in-out none-out 3WR Type2
Homo sapiens TNK2 ACK1_HUMAN Activated CDC42 kinase 1 5ZXBA 2.198 in-in none-none 9KO Type2
Homo sapiens TNK2 ACK1_HUMAN Activated CDC42 kinase 1 5ZXBB 2.198 in-in none-none 9KO Type2
Leishmania donovani MPK3 A0A3S7WR45_LEIDO Mitogen-activated protein kinase 4O2ZA 2.71 in-in out-out 046 Type2
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 3UBDA 1.53 none-none out-out SL0 Type1
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 4EL9A 1.55 none-none out-out AFE Type1
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 4GUEA 1.8 none-none out-out QCT Type1
Mus musculus MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7BDOA 2.7 in-out none-out TBK Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 6OKOA 2.1 in-in none-out 1FN Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 6OKOB 2.1 in-out none-none 1FN Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX2A 2.39 in-none none-none 1SU Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX3A 2.07 in-in none-none A1EAA Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX3B 2.07 in-in none-none A1EAA Type2
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1M52A 2.6 in-in out-in P17 Type1.5_Back
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1M52B 2.6 in-in out-in P17 Type1.5_Back
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1OPKA 1.8 in-in out-in P16 Type1.5_Back
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34A 2.8 out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34B 2.8 out-out none-out No_ligand No_ligand
Rattus norvegicus MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4I5HA 1.9 in-in out-out G17 Type2
Salmo salar P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTA 2.7 in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Salmo salar P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTB 2.7 in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Toxoplasma gondii PRP4K S7UT92_TOXGG non-specific serine/threonine protein kinase 7Q4AA 2.31 in-in out-out A9I Type2
Toxoplasma gondii PRP4K S7UT92_TOXGG non-specific serine/threonine protein kinase 7Q4AB 2.31 in-out out-out A9I Type2
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8A 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8B 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8C 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8D 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8E 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8F 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8G 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8H 3.6 in-in out-out No_ligand No_ligand

All kinases with DFGout - None conformation

Total number of genes: 13
Total number of chains: 43
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGout None 3 0 0 7 0 0 0 6 12 15 4I93A
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I92A 1.6 out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93A 1.5 out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93B 1.5 out-out out-none No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94A 1.8 out-out out-out ANP Type1
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94B 1.8 out-out out-out ANP Type1
Arabidopsis thaliana CTR1 CTR1_ARATH Serine/threonine-protein kinase CTR1 3P86A 2.496 out-out none-out STU Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3D7TB 2.899 in-in out-in STU Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5K9IB 2.5 out-out in-in O44 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OB 2.69 out-out none-out TZ0 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3EL7A 2.8 in-in none-none PD3 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3EL8A 2.3 in-in in-out PD5 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3G6GB 2.31 in-in none-out G6G Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4AGWA 2.6 in-in none-none NG7 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4AGWB 2.6 in-in none-none NG7 Type2
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3TZ9B 3.1 in-in none-out AQU Type2
Leishmania donovani MPK3 A0A3S7WR45_LEIDO Mitogen-activated protein kinase 4O2ZA 2.71 in-in out-out 046 Type2
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 3UBDA 1.53 none-none out-out SL0 Type1
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 4EL9A 1.55 none-none out-out AFE Type1
Mus musculus RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 4GUEA 1.8 none-none out-out QCT Type1
Mus musculus MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7BDOA 2.7 in-out none-out TBK Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 6OKOA 2.1 in-in none-out 1FN Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 6OKOB 2.1 in-out none-none 1FN Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX2A 2.39 in-none none-none 1SU Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX3A 2.07 in-in none-none A1EAA Type2
Mus musculus RIPK3 RIPK3_MOUSE Receptor-interacting serine/threonine-protein kinase 3 9IX3B 2.07 in-in none-none A1EAA Type2
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1M52A 2.6 in-in out-in P17 Type1.5_Back
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1M52B 2.6 in-in out-in P17 Type1.5_Back
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 1OPKA 1.8 in-in out-in P16 Type1.5_Back
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34A 2.8 out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34B 2.8 out-out none-out No_ligand No_ligand
Rattus norvegicus MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4I5HA 1.9 in-in out-out G17 Type2
Salmo salar P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTA 2.7 in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Salmo salar P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTB 2.7 in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Toxoplasma gondii PRP4K S7UT92_TOXGG non-specific serine/threonine protein kinase 7Q4AA 2.31 in-in out-out A9I Type2
Toxoplasma gondii PRP4K S7UT92_TOXGG non-specific serine/threonine protein kinase 7Q4AB 2.31 in-out out-out A9I Type2
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8A 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8B 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8C 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8D 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8E 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8F 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8G 3.6 in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8H 3.6 in-in out-out No_ligand No_ligand