CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 171
Active chains: 160
Uniprot: CHK1_HUMAN
Kinase Domain Residues: 9 - 265
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 171 100.0% AF-O14757-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1
3JVRA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGX Allosteric 2 - 272 0 None None Serine/threonine-protein kinase Chk1
3F9NA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 38M Allosteric 7 - 270 0 None None Serine/threonine-protein kinase Chk1
AF-O14757-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase Chk1
AF-O14757-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase Chk1
1IA8A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 276 0 None None Serine/threonine-protein kinase Chk1
7AKMB 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 269 0 None D10R Serine/threonine-protein kinase Chk1
1ZYSA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 199 Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
2E9VA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 85A Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1
2E9VB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 85A Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1
2E9OA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A58 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
2E9PA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 77A Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
2E9UA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A25 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
2GHGA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A53 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
2YWPA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A42 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
3OT3A 1.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 22K Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1
3OT8A 1.645 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MI5 Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1
3PA3A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C70 Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1
3PA4A 1.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C72 Type1 6 - 272 0 None None Serine/threonine-protein kinase Chk1
3PA5A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C73 Type1 3 - 272 0 None None Serine/threonine-protein kinase Chk1
3U9NA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 09H Type1 7 - 272 0 None None Serine/threonine-protein kinase Chk1
4JIKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1KO Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1
2X8EA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8E Type1 9 - 270 0 None None Serine/threonine-protein kinase Chk1
2YDJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 8 - 269 0 None None Serine/threonine-protein kinase Chk1
2YDJB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1
2YDKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDK Type1 3 - 270 0 None None Serine/threonine-protein kinase Chk1
2YERA 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TQ1 Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1
2YEXA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEX Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
6FC8A 1.61 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D4Q Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
6FCFA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D58 Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1
6FCKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D4Z Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1
4FSNA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A58 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FSMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK1 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FSRA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HKC Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FSWA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK6 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FSYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK7 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FSZA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK8 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FT0A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK9 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FT3A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H1K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
4FT5A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H2K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FT7A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H3K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FT9A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H4K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTAA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H5K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTCA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H6K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTIA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H7K Type1 3 - 279 0 None None Serine/threonine-protein kinase Chk1
4FTJA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H8K Type1 3 - 279 0 None None Serine/threonine-protein kinase Chk1
4FTOA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HK Type1 3 - 271 0 None None Serine/threonine-protein kinase Chk1
4FTQA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4HK Type1 3 - 270 0 None None Serine/threonine-protein kinase Chk1
4FTRA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5HK Type1 3 - 271 0 None None Serine/threonine-protein kinase Chk1
4FTTA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6HK Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTUA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7HK Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4GH2A 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK0 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
1NVQA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UCN Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
1NVRA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
1NVSA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UCM Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
2WMQA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYQ Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1
2WMRA 2.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYR Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1
2WMSA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYS Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1
2WMTA 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYT Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1
2WMUA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYU Type1 9 - 270 0 None None Serine/threonine-protein kinase Chk1
2WMVA 2.009 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYV Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1
2WMWA 2.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYW Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1
2WMXA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZY6 Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1
2X8DA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8D Type1 2 - 281 0 None None Serine/threonine-protein kinase Chk1
2X8IA 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8I Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1
2XEYA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YVQ Type1 6 - 269 0 None None Serine/threonine-protein kinase Chk1
2XEZA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XEZ Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1
2XF0A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4UB Type1 4 - 270 0 None None Serine/threonine-protein kinase Chk1
2YDIA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDI Type1 2 - 281 0 None None Serine/threonine-protein kinase Chk1
2YM3A 2.007 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM3 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1
2YM4A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4YM Type1 4 - 270 0 None None Serine/threonine-protein kinase Chk1
2YM8A 2.07 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM8 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1
4HYHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1AM Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1
4HYIA 1.399 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1AO Type1 3 - 274 0 None None Serine/threonine-protein kinase Chk1
1ZLTA 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HYM Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2GDOA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 12C Type1 1 - 273 0 None None Serine/threonine-protein kinase Chk1
2BR1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PFP Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2BRBA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PFQ Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2BRGA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFY Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1
2BRHA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFW Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1
2BRMA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFZ Type1 7 - 274 0 None None Serine/threonine-protein kinase Chk1
2BRNA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DF1 Type1 6 - 276 0 None None Serine/threonine-protein kinase Chk1
2BROA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DF2 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2C3JA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DBQ Type1 6 - 270 0 None None Serine/threonine-protein kinase Chk1
2C3LA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDZ Type1 2 - 273 0 None None Serine/threonine-protein kinase Chk1
2CGUA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3A3 Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1
2CGVA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3B3 Type1 6 - 272 0 None None Serine/threonine-protein kinase Chk1
2CGWA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3C3 Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1
2CGXA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3D3 Type1 6 - 273 0 None None Serine/threonine-protein kinase Chk1
3NLBA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BE Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1
5DLSA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5CV Type1 6 - 270 0 None None Serine/threonine-protein kinase Chk1
7BKNA 2.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1
7BKOA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVW Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1
4QYEA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DL Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4QYFA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DV Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4QYGA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DW Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4QYGB 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DW Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4QYHA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DX Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4QYHB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DX Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4RVKA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3XK Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4RVLA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3XL Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
4RVMA 1.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3X7 Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1
7AKOA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1
7AKOB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1
2HOGA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 710 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
2HXLA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 422 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2QHMA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7CS Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
2QHNA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 582 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
2R0UA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M54 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
3TKHA 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 07S Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
3TKIA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii S25 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
5OQ5A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1
5OQ7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1
5OQ7B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1
4FSUA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK5 Type1 4 - 271 0 None None Serine/threonine-protein kinase Chk1
5OQ6A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 5 - 270 0 None A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OQ8A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 4 - 270 0 None A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
9CE4A 1.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AV4 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OOTA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OP2A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OP4A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0T Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OP5A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3FE Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OP7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1K Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OPBA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OPRA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3E Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OPSA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3Q Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OPUA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3K Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5OPVA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3H Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJDA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVT Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJEA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJHA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 42C Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJJA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVW Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJOA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TWK Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJRA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TWH Type1 5 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BK1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0N Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BK2A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0K Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BK3A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0T Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7MCKA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YXD Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUFA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BVI Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUGA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BWI Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUHA 2.46 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BXI Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUIA 2.119 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L80 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUJB 2.299 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BYL Type1 9 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8E80A 1.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UUF Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8E81A 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UU6 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8SIVA 1.759 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXH Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8SIWA 1.877 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXL Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8SIWB 1.877 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXL Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
8SIXA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXP Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
5F4NA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5UY, 5UY Type1, Allosteric 5 - 271 0 None None Serine/threonine-protein kinase Chk1
2YM7A 1.81 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM7, YM7 Type1, Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1
4FSTA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK4 Type1.5_Back 3 - 270 0 None None Serine/threonine-protein kinase Chk1
2AYPA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 43A Type1.5_Back 2 - 269 0 None None Serine/threonine-protein kinase Chk1
4FSQA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK3 Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTKA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H9K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTMA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1HK Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
4FTNA 2.02 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2HK Type1.5_Back 3 - 271 0 None None Serine/threonine-protein kinase Chk1
2C3KA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ABO Type1.5_Back 6 - 270 0 None None Serine/threonine-protein kinase Chk1
5OOPA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
3JVSA 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGY Allosteric 2 - 272 0 None None Serine/threonine-protein kinase Chk1
2YM5A 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YM5 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1
2YM6A 2.01 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YM6 Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1
2HXQA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 373 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1
2HY0A 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 306 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1
5OORA 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 3 - 283 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7BJMA 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TW2 Type1 5 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
7SUJA 2.299 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii BYL Type1 9 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1
2E9NA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76A Type1.5_Back 2 - 270 0 None None Serine/threonine-protein kinase Chk1
4FTLA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H0K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1

CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 171
Active chains: 160
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 171 100.0% AF-O14757-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CHK1_HUMAN 7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3JVRA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGX Allosteric 2 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3F9NA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 38M Allosteric 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN AF-O14757-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN AF-O14757-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1IA8A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7AKMB 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 2 - 269 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1ZYSA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 199 Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9VA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 85A Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9VB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 85A Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9OA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A58 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9PA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 77A Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9UA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A25 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2GHGA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A53 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YWPA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A42 Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3OT3A 1.44 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 22K Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3OT8A 1.645 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MI5 Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3PA3A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C70 Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3PA4A 1.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C72 Type1 6 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3PA5A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C73 Type1 3 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3U9NA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 09H Type1 7 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4JIKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1KO Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2X8EA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8E Type1 9 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YDJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 8 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YDJB 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YDKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDK Type1 3 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YERA 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TQ1 Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YEXA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YEX Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 6FC8A 1.61 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D4Q Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 6FCFA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D58 Type1 9 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 6FCKA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D4Z Type1 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSNA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A58 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK1 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSRA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HKC Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSWA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK6 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK7 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSZA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK8 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FT0A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK9 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FT3A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H1K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FT5A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H2K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FT7A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H3K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FT9A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H4K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTAA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H5K Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTCA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H6K Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTIA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H7K Type1 3 - 279 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTJA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H8K Type1 3 - 279 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTOA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HK Type1 3 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTQA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4HK Type1 3 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTRA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5HK Type1 3 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTTA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6HK Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTUA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7HK Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4GH2A 2.03 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK0 Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1NVQA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UCN Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1NVRA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1NVSA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UCM Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMQA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYQ Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMRA 2.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYR Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMSA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYS Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMTA 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYT Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMUA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYU Type1 9 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMVA 2.009 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYV Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMWA 2.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZYW Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2WMXA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZY6 Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2X8DA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8D Type1 2 - 281 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2X8IA 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X8I Type1 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2XEYA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YVQ Type1 6 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2XEZA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XEZ Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2XF0A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4UB Type1 4 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YDIA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDI Type1 2 - 281 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM3A 2.007 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM3 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM4A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4YM Type1 4 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM8A 2.07 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM8 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4HYHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1AM Type1 4 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4HYIA 1.399 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1AO Type1 3 - 274 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 1ZLTA 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HYM Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2GDOA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 12C Type1 1 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BR1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PFP Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BRBA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PFQ Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BRGA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFY Type1 7 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BRHA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFW Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BRMA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFZ Type1 7 - 274 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BRNA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DF1 Type1 6 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2BROA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DF2 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2C3JA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DBQ Type1 6 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2C3LA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDZ Type1 2 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2CGUA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3A3 Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2CGVA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3B3 Type1 6 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2CGWA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3C3 Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2CGXA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3D3 Type1 6 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3NLBA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5BE Type1 6 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5DLSA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5CV Type1 6 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BKNA 2.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BKOA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVW Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYEA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DL Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYFA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DV Type1 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYGA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DW Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYGB 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DW Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYHA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DX Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4QYHB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3DX Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4RVKA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3XK Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4RVLA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3XL Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4RVMA 1.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3X7 Type1 3 - 273 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7AKOA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7AKOB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2HOGA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 710 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2HXLA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 422 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2QHMA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7CS Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2QHNA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 582 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2R0UA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M54 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3TKHA 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 07S Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3TKIA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii S25 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OQ5A 1.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OQ7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OQ7B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSUA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK5 Type1 4 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OQ6A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 5 - 270 0 None A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OQ8A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 4 - 270 0 None A19S,Y20F,N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 9CE4A 1.31 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1AV4 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OOTA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4K4 Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OP2A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0Q Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OP4A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A0T Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OP5A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3FE Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OP7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1K Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OPBA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1N Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OPRA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3E Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OPSA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3Q Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OPUA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3K Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OPVA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A3H Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJDA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVT Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJEA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJHA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 42C Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJJA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TVW Type1 3 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJOA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TWK Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJRA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TWH Type1 5 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0Q Type1 8 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BK1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0N Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BK2A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0K Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BK3A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U0T Type1 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7MCKA 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YXD Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUFA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BVI Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUGA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BWI Type1 3 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUHA 2.46 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BXI Type1 4 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUIA 2.119 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L80 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUJB 2.299 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BYL Type1 9 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8E80A 1.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UUF Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8E81A 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UU6 Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8SIVA 1.759 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXH Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8SIWA 1.877 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXL Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8SIWB 1.877 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXL Type1 4 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 8SIXA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZXP Type1 8 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5F4NA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5UY, 5UY Type1, Allosteric 5 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM7A 1.81 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YM7, YM7 Type1, Type1 7 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSTA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK4 Type1.5_Back 3 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2AYPA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 43A Type1.5_Back 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FSQA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK3 Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTKA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H9K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTMA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1HK Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTNA 2.02 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2HK Type1.5_Back 3 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2C3KA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ABO Type1.5_Back 6 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OOPA 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 3JVSA 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGY Allosteric 2 - 272 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM5A 2.03 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YM5 Type1 8 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2YM6A 2.01 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii YM6 Type1 7 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2HXQA 2.0 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 373 Type1 2 - 276 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2HY0A 1.7 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 306 Type1 2 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 5OORA 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 3 - 283 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7BJMA 2.3 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TW2 Type1 5 - 270 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 7SUJA 2.299 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii BYL Type1 9 - 271 0 None N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 2E9NA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76A Type1.5_Back 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CHK1_HUMAN 4FTLA 2.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H0K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens

CAMK_CHEK1 (Serine/threonine-protein kinase Chk1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism