9BCS

NPR1 (Atrial natriuretic peptide receptor 1)
Pseudokinase
Group: RGC
Uniprot: ANPRA_HUMAN
Organism: Homo sapiens
Domain boundary: 533 - 803
Resolu: 4.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-none out-out ATP Type1 503 - 1055 0
B Inactive None None out-none out-out ATP Type1 505 - 1055 0
Representative sequence - Chain B
- 41 51 61
dykddddkaa agnltvavvl plantsypws warvgpavel
71 81 91 101
alaqvkarpd llpgwtvrtv lgssenalgv csdtaaplaa
111 121 131 141
vdlkwehnpa vflgpgcvya aapvgrftah wrvplltaga
151 161 171 181
palgfgvkde yalttragps yaklgdfvaa lhrrlgwerq
191 201 211 221
almlyayrpg deehcfflve glfmrvrdrl nitvdhlefa
231 241 251 261
eddlshytrl lrtmprkgrv iyicsspdaf rtlmllalea
271 281 291 301
glcgedyvff hldifgqslq ggqgpaprrp wergdgqdvs
311 321 331 341
arqafqaaki itykdpdnpe yleflkqlkh layeqfnftm
351 361 371 381
edglvntipa sfhdglllyi qavtetlahg gtvtdgenit
391 401 411 421
qrmwnrsfqg vtgylkidss gdretdfslw dmdpengafr
431 441 451 461
vvlnyngtsq elvavsgrkl nwplgypppd ipkcgfdned
471 481 491 501
pacnqdhlst levlalvgsl sllgilivsf fiyrkmqlek
511 521 531 541
elaSELWRVR WEDVEPSSLE RHLRSAGSrl tlsgrgsnyg
551 561 571 581
sllttegqfq vfaktaYYKG NLVAVKRVNR KRIELTRKVL
591 601 611 621
FELKHMRDVQ NEHLTRFVGA CTDPPNICIL TEYCPRGSLQ
631 641 651 661
DILENESITL DWMFRYSLTN DIVKGMLFLH NGAICSHGNL
671 681 691 701
KSSNCVVDGR FVLKITDYGL ESFRDLDPEQ GHTVYAKKLW
711 721 731 741
TAPELLRMAS PPVRGSQAGD VYSFGIILQE IALRSGVFHV
751 761 771 781
EGLDLSPKEI IERVTRGEQP PFRPSLALQS HLEELGLLMQ
791 801 811 821
RCWAEDPQER PPFQQIRLTL RKFNRENSSN ILDNLLSRME
831 841 851 861
QYANNLEELV EERTQAYLEE KRKAEALLYQ ILPHSVAEQL
871 881 891 901
KRGETVQAEA FDSVTIYFSD IVGFTALSAE STPMQVVTLL
911 921 931 941
NDLYTCFDAV IDNFDVYKVE TIGDAYMVVS GLPVRNGRLH
951 961 971 981
ACEVARMALA LLDAVRSFRI RHRPQEQLRL RIGIHTGPVC
991 1001 1011 1021
AGVVGLKMPR YCLFGDTVNT ASRMESNGEA LKIHLSSETK
1031 1041 1051 1061
AVLEEFGGFE LELRGDVEMK GKGKVRTYWL LGERgsstrg


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None