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Total number of chains: 572
Active chains: 171
Total number of genes: 50
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 350 61.2% AF-Q2M2I8-K1A
DFGin ABAminus 97 17.0% AF-Q504Y2-K3A
DFGin None 37 6.5% 5O23A
DFGin BLBplus 22 3.8% 3P23C
DFGin BLBminus 19 3.3% 5O1VA
None None 19 3.3% 7BL1CCC
DFGout None 13 2.3% 6O5ZB
DFGout BBAminus 5 0.9% 6FDZU
DFGin BLAplus 4 0.7% 7JXUA
DFGin BLBtrans 3 0.5% 5J0AA
DFGinter None 2 0.3% 8OMVE
DFGinter BABtrans 1 0.2% 7QWKH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER AAK1 AAK1_HUMAN AF-Q2M2I8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 321 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN AF-Q2M2I8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 321 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 4WSQA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 29 - 345 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 4WSQB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 33 - 342 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 8GMCA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 34 - 330 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 8GMCB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 31 - 330 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 8GMDA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRR Type1 34 - 329 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 8GMDB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRR Type1 29 - 330 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 9QB5A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F7I Type1 29 - 343 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 9QB5B 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F7I Type1 34 - 342 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 5L4QA 1.97 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LKB Type1 33 - 335 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 5L4QB 1.97 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LKB Type1 33 - 333 0 None None AP2-associated protein kinase 1
OTHER AAK1 AAK1_HUMAN 5TE0A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIN Type1 27 - 345 0 None None AP2-associated protein kinase 1
OTHER BMP2K BMP2K_HUMAN 5I3OA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3OB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3RA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5I3RB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 5IKWA 2.41 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6BU Type1 42 - 338 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN AF-Q9NSY1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 43 - 325 0 None None BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN AF-Q9NSY1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 43 - 325 0 None None BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 4W9XA 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3JW Type1 39 - 342 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BMP2K BMP2K_HUMAN 4W9WA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ, YDJ Type1, Allosteric 39 - 344 0 None K320A,K321A BMP-2-inducible protein kinase
OTHER BUB1 BUB1_HUMAN 4QPMA 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 4QPMB 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1081 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 4R8QA 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iooo ADP ATPlike 736 - 1083 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 5DMZA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 5DMZB 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN AF-O43683-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 779 - 1064 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN AF-O43683-K3A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 779 - 1064 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER BUB1 BUB1_HUMAN 6F7BA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iioo CVQ Type1 733 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA8A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN AF-O00311-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN AF-O00311-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9BA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9BC 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 4F9CA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase
OTHER CDC7 CDC7_HUMAN 6YA6A 1.44 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase
OTHER CHUK IKKA_HUMAN AF-O15111-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN AF-O15111-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZA 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZB 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZC 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZD 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZE 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZF 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZG 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZH 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZI 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZJ 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZK 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5EBZL 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQWA 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQWB 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQXA 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQXB 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQYA 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER CHUK IKKA_HUMAN 5TQYB 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
OTHER DSTYK DUSTY_HUMAN AF-Q6XUX3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 644 - 916 0 None None Dual serine/threonine and tyrosine protein kinase
OTHER DSTYK DUSTY_HUMAN AF-Q6XUX3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 644 - 916 0 None None Dual serine/threonine and tyrosine protein kinase
OTHER EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 159 - 591 0 None None Eukaryotic translation initiation factor 2-alpha kinase 1
OTHER EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 159 - 591 0 None None Eukaryotic translation initiation factor 2-alpha kinase 1
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 2A1AB 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo No_ligand No_ligand 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 8QELB 2.451 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo UH3 Type1 258 - 541 0 TPO446 None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 256 - 544 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn ADP ATPlike 255 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3KC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 257 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN AF-P19525-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 259 - 546 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN AF-P19525-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 259 - 546 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 6D3LA 3.1 Inactive DFGin‑None in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 258 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 3UIUA 2.903 Inactive DFGin‑None in-none in-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 254 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK2 E2AK2_HUMAN 3UIUB 2.903 Inactive DFGin‑None in-none in-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 254 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase
OTHER EIF2AK3 E2AK3_HUMAN AF-Q9NZJ5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 585 - 1085 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN AF-Q9NZJ5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 585 - 1085 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7OA 2.65 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z6 Type1 585 - 1081 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 7MF0AAA 2.809 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn Z6P Type1 586 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 8EQ9AAA 2.86 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn WPB Type1 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 8EQDAAA 2.92 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WPX Type1 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4G31A 2.28 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 0WH Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4G34A 2.7 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 924 Type1.5_Back 588 - 1079 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4M7IA 2.34 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 27D Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 8EQEAAA 2.559 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WQ2 Type1.5_Back 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7JA 2.3 Inactive DFGout‑BBAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 3Z1 Type1 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7KA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z3 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7LA 1.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z4 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7HA 2.0 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 3Z2 Type2 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK4-2 E2AK4_HUMAN AF-Q9P2K8-K2A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 582 - 1009 0 None None eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN AF-Q9P2K8-K4A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 582 - 1009 0 None None eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3NA 3.01 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA4 Type1 584 - 1003 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3OA 2.4 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA7 Type1.5_Back 584 - 1004 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6A 2.8 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 38O Type1 584 - 1004 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6B 2.8 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_oooo 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6C 2.8 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6D 2.8 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKH 2.3 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaoni APEdist_oooo G41 Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKF 2.3 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaoni APEdist_oooo G41 Type1 584 - 1005 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKA 2.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 998 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKB 2.3 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 998 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKC 2.3 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aanni APEdist_nnnn G41 Type1 583 - 1004 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKD 2.3 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 1003 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKE 2.3 Inactive DFGout‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn G41 Type1 584 - 1004 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKG 2.3 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aanni APEdist_nnnn G41 Type1 584 - 1007 0 None D848N eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LA 2.61 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aanni APEdist_nnnn KAV Type2 584 - 1002 0 None K807A,D848N,T899A,T904A eIF-2-alpha kinase GCN2
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LB 2.61 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aanni APEdist_nnnn KAV Type2 584 - 1002 0 None K807A,D848N,T899A,T904A eIF-2-alpha kinase GCN2
OTHER ERN1 ERN1_HUMAN 4Z7HB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioi 4L5 Type1 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN AF-O75460-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 561 - 840 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN AF-O75460-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 561 - 840 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 5HGIA 2.584 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDFB 2.54 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio No_ligand No_ligand 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3BA 2.57 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZCA 2.494 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZCB 2.494 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9GOWA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9GOWB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9GOWC 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9GOWD 3.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3KA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii SJS Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3EB 2.737 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nnoo SJV Type1.5_Back 563 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDFA 2.54 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N94 Type1.5_Back 560 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 7BMKA 1.85 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi U4N Type1.5_Back 561 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 7BMKB 1.85 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_ioio U4N Type1.5_Back 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6URCA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6URCB 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDDB 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N97 Type1.5_Back 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4U6RA 2.5 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi 3E4 Type1.5_Back 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDBA 2.45 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N8S Type1.5_Back 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3EA 2.737 Inactive DFGin‑BLAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn SJV Type1.5_Front 562 - 962 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDDA 2.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiio APEdist_oiio N97 Type1.5_Front 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 8UVLA 2.43 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi XOE Type1.5_Front 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9N88A 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 9N88E 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W39A 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W39B 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3AA 2.606 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3AB 2.606 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4Z7GA 2.6 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4Z7GB 2.6 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4Z7HA 2.9 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 4L5 Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZ9A 2.463 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZ9B 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 4K7 Type3 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZ9C 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6HX1A 2.14 Inactive None‑None none-none out-out nonTYR APEdihe_aaooi APEdist_iioo GXK Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6HV0A 2.73 Inactive None‑None none-none out-out nonTYR APEdihe_aaoii APEdist_iioo GUK Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN2 ERN2_HUMAN AF-Q76MJ5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 510 - 789 0 None None Serine/threonine-protein kinase/endoribonuclease IRE2
OTHER ERN2 ERN2_HUMAN AF-Q76MJ5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 510 - 789 0 None None Serine/threonine-protein kinase/endoribonuclease IRE2
OTHER GAK GAK_HUMAN 4O38A 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 25 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4O38B 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 26 - 337 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y7ZA 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y7ZB 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 5Y80A 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo IRE, IRE Type1, Allosteric 25 - 332 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN AF-O14976-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 323 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN AF-O14976-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 323 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4Y8DA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4Y8DB 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN AF-Q8TF76-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN AF-Q8TF76-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 2WB8A 2.15 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 447 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 5HTBA 1.7 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 5HTCA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9B2SK 3.01 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9B2UK 3.64 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G39A 1.45 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605Y Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 2VUWA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLTA 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDF Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 3E7VA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DZO Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 3F2NA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IZZ Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 3FMDA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IQB Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 3IQ7A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 4OUCA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 4QTCA 1.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 38Z Type1 469 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G34A 1.76 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G35A 1.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKK Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G36A 1.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKH Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G37A 1.48 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa FTU Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G38A 1.47 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBN Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z57A 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8W Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z58A 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q9B Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z59A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q98 Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5CA 1.75 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa PQ5 Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5DA 1.75 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8Q Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5EA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8K Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 7AVQA 1.65 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa S1Z Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 7OPSA 2.38 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 07C Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 8RDKA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa YQT Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLBA 2.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDB Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLOA 2.9 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDC Type1 466 - 797 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLQA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDD Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLRA 1.91 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDE Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 7SQMA 1.78 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A5G Type1 453 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6G3AA 1.43 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605T Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z56A 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5BA 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLCA 2.18 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9B2TK 2.99 Inactive DFGin‑None out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER IKBKB IKKB_HUMAN AF-O14920-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 316 0 None None Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN AF-O14920-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 316 0 None None Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CB 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iooo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CC 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CD 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CF 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 8OMVC 4.16 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 12 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 8OMVD 4.16 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioo APEdist_niio No_ligand No_ligand 6 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4KIKA 2.83 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo KSA Type1 9 - 663 0 SEP257 None Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4KIKB 2.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 2 - 663 0 SEP177,SEP181 None Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 8OMVB 4.16 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 8 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CA 3.98 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CE 3.98 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 8OMVE 4.16 Inactive DFGinter‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iiio No_ligand No_ligand 9 - 643 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 8OMVA 4.16 Inactive None‑None in-in out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 8 - 666 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKE IKKE_HUMAN AF-Q14164-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Inhibitor of nuclear factor kappa-B kinase subunit epsilon
OTHER IKBKE IKKE_HUMAN AF-Q14164-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Inhibitor of nuclear factor kappa-B kinase subunit epsilon
OTHER MLKL MLKL_HUMAN 6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER MOS MOS_HUMAN AF-P00540-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 346 0 None None Proto-oncogene serine/threonine-protein kinase mos
OTHER MOS MOS_HUMAN AF-P00540-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 346 0 None None Proto-oncogene serine/threonine-protein kinase mos
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PBK TOPK_HUMAN AF-Q96KB5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 24 - 322 0 None None Lymphokine-activated killer T-cell-originated protein kinase
OTHER PBK TOPK_HUMAN AF-Q96KB5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 24 - 322 0 None None Lymphokine-activated killer T-cell-originated protein kinase
OTHER PBK TOPK_HUMAN 5J0AA 2.74 Inactive DFGin‑BLBtrans out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 23 - 320 0 None T198E Lymphokine-activated killer T-cell-originated protein kinase
OTHER PBK TOPK_HUMAN 5J0AB 2.74 Inactive DFGin‑BLBtrans out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 19 - 319 0 None T198E Lymphokine-activated killer T-cell-originated protein kinase
OTHER PDIK1L PDK1L_HUMAN AF-Q8N165-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 339 0 None None Serine/threonine-protein kinase PDIK1L
OTHER PDIK1L PDK1L_HUMAN AF-Q8N165-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 339 0 None None Serine/threonine-protein kinase PDIK1L
OTHER PEAK1 PEAK1_HUMAN 6BHCA 2.3 Pseudo DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaoai APEdist_nnno No_ligand No_ligand 1285 - 1743 0 None S1542T Inactive tyrosine-protein kinase PEAK1
OTHER PIK3R4 A0JP11_HUMAN 9ZPDA 3.38 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 A0JP11_HUMAN 9ZPCA 3.83 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9C82A 6.84 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 64 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 7BL1CCC 9.8 Pseudo None‑None out-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 12 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHHA 4.5 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 16 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PINK1 PINK1_HUMAN AF-Q9BXM7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 148 - 517 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN AF-Q9BXM7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 148 - 517 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9EIHA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9EIHB 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9EIIB 2.75 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9EIJB 3.3 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9KOXC 4.43 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 156 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9KQNC 2.84 Inactive None‑None none-none none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 305 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PINK1 PINK1_HUMAN 9KMRC 2.98 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 156 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K3A -1.0 Active DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC
OTHER PKMYT1 PMYT1_HUMAN AF-Q99640-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 102 - 367 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN AF-Q99640-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 102 - 367 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 3P1AA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi No_ligand No_ligand 76 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8ZTXA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D83 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGVB 2.041 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8ZU2A 1.799 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D85 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8ZUDA 1.505 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D82 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8ZULA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D84 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGLA 2.17 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJW Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGLB 2.17 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJW Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCVA 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 1N1 Type1 75 - 361 0 TPO260 None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCWA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 93J Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCWB 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 93J Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCXA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi H8H Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCYA 1.56 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi DB8 Type1 77 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VCZA 1.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VD0A 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VD1A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi P48 Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 5VD3A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi H8H Type1 78 - 360 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6CA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGR Type1 78 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6CB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGR Type1 77 - 360 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6DB 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6EB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8WJYA 1.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nooi W9X Type1 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9M6PAAA 2.383 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnoi A1EMX Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGVA 2.041 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LIDA 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LIDB 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGNA 2.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGNB 2.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6DA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6EA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6FA 2.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6FB 2.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9M6PBBB 2.383 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii A1EMX Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PRAG1 PRAG1_HUMAN 5VE6A 2.953 Pseudo None‑None none-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 944 - 1405 0 None None Inactive tyrosine-protein kinase PRAG1
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER SBK1 SBK1_HUMAN AF-Q52WX2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 45 - 323 0 None None Serine/threonine-protein kinase SBK1
OTHER SBK1 SBK1_HUMAN AF-Q52WX2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 45 - 323 0 None None Serine/threonine-protein kinase SBK1
OTHER SBK2 SBK2_HUMAN AF-P0C263-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iioi No_ligand No_ligand 54 - 335 0 None None Serine/threonine-protein kinase SBK2
OTHER SBK2 SBK2_HUMAN AF-P0C263-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 54 - 335 0 None None Serine/threonine-protein kinase SBK2
OTHER SBK3 SBK3_HUMAN AF-P0C264-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iioi No_ligand No_ligand 35 - 314 0 None None Uncharacterized serine/threonine-protein kinase SBK3
OTHER SBK3 SBK3_HUMAN AF-P0C264-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 35 - 314 0 None None Uncharacterized serine/threonine-protein kinase SBK3
OTHER STK16 STK16_HUMAN AF-O75716-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 300 0 None None Serine/threonine-protein kinase 16
OTHER STK16 STK16_HUMAN AF-O75716-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 300 0 None None Serine/threonine-protein kinase 16
OTHER STK16 STK16_HUMAN 2BUJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, STU Type1, Allosteric 13 - 299 0 None R19H,R266W Serine/threonine-protein kinase 16
OTHER STK16 STK16_HUMAN 2BUJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, STU Type1, Type1 13 - 297 0 None R19H,R266W Serine/threonine-protein kinase 16
OTHER STK35 STK35_HUMAN AF-Q8TDR2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 534 0 None None Serine/threonine-protein kinase 35
OTHER STK35 STK35_HUMAN AF-Q8TDR2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 534 0 None None Serine/threonine-protein kinase 35
OTHER STK36 STK36_HUMAN AF-Q9NRP7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 262 0 None None Serine/threonine-protein kinase 36
OTHER STK36 STK36_HUMAN AF-Q9NRP7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 262 0 None None Serine/threonine-protein kinase 36
OTHER TBK1 TBK1_HUMAN AF-Q9UHD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN AF-Q9UHD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4EUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 307 0 SEP172 D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4EUUB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 307 0 SEP172 D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4EUTA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo BX7 Type1 2 - 385 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4EUTB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo BX7 Type1 2 - 385 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IW0A 4.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 657 0 SEP172 D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6O8BA 3.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_oiii BX7 Type1 2 - 656 0 None D135N,S172E Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6O8BB 3.4 Inactive DFGin‑BLAminus in-in out-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 654 0 None D135N,S172E Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6NT9A 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6NT9B 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 5W5VA 3.645 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANW Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6BODA 3.197 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn E0P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6RSTA 3.29 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHQ Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IWOA 2.61 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1H4 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM2A 2.5 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IM3A 3.342 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6BNYA 3.341 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn E0M Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6BOEA 3.598 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aaiii APEdist_nnni E0S Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6CQ0A 3.19 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_nnno F8M Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6CQ4A 3.2 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aaiii APEdist_nnni F8P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6CQ5A 3.354 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn F8S Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6RSRA 3.15 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHT Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 6RSUA 2.75 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KJB Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IWPA 3.065 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni BX7 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IWQA 3.0 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1FV Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1
OTHER TLK1 TLK1_HUMAN AF-Q9UKI8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 448 - 742 0 None None Serine/threonine-protein kinase tousled-like 1
OTHER TLK1 TLK1_HUMAN AF-Q9UKI8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 448 - 742 0 None None Serine/threonine-protein kinase tousled-like 1
OTHER TLK2 TLK2_HUMAN 5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2
OTHER TLK2 TLK2_HUMAN AF-Q86UE8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2
OTHER TLK2 TLK2_HUMAN AF-Q86UE8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN AF-Q96S44-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 25 - 253 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN AF-Q96S44-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 25 - 253 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 9FL9B 3.74 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZAA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DUI Type1 14 - 246 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZAC 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DUI Type1 18 - 245 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZBA 2.02 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DQ4 Type1 14 - 245 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZBC 2.02 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DQ4 Type1 18 - 245 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZCA 1.71 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DO0 Type1 18 - 246 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZCC 1.71 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DO0 Type1 18 - 246 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZDA 2.05 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DVO Type1 18 - 249 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 7SZDC 2.05 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DVO Type1 18 - 249 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3CEKA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3DBQA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 515 - 796 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2ZMCA 3.14 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6GVJA 2.41 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 515 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5LJJA 3.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AD5 Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5MRBA 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EH0A 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5NW Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6H3KA 2.48 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn FMW Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4JS8A 1.94 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo 1PF Type1 515 - 793 0 TPO675,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4JT3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1PH Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4O6LA 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4O6LB 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4ZEGA 2.33 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 052 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CILA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo FZR Type1 515 - 795 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CHNA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo FZL Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CJAA 2.49 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo G0U Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CLHA 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo G5C Type1 516 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TN9A 2.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo NN5 Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNCA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo O23 Type1 516 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6N6OA 2.6 Inactive DFGin‑ABAminus out-out out-none nonTYR APEdihe_aanni APEdist_nnnn KE7 Type1 515 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BHZA 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0B Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI0A 2.84 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0W Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI1A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO6 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4BI2A 3.11 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO8 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4EA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 4T9 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4FA 2.36 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 7CE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4GA 2.65 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaono APEdist_nnoo 7RO Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4HA 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 7RO Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4IA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X20 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4C4JA 2.5 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo X21 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CV8A 3.0 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno 3D7 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CV9A 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo W2K Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 4CVAA 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo WBI Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP0A 2.15 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo AU5 Type1 519 - 795 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP1A 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo O38 Type1 519 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP2A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno PWU Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHLA 2.66 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo 0SQ Type1 519 - 796 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHOA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O1 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EHYA 2.26 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O4 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI2A 2.67 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5O7 Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI6A 2.01 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5OQ Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5EI8A 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5OE Type1 519 - 753 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N87A 2.29 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo N66 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP6A 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo PWU Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5O91A 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 796 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6B4WA 2.9 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnoo CQ7 Type1 515 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3VQUA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno O22 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WYXA 2.9 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O38 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WYYA 3.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O17 Type1 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N7VA 2.52 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaono APEdist_oooo 8PT Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N84A 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo 8Q5 Type1 519 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N93A 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo 8QE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NA0A 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo 8QZ Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3HMOA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 514 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3HMPA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo CX4 Type1 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP3A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_iooo AU5 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP4A 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo O38 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2ZMDA 2.88 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_oooo 537 Type1 516 - 795 0 None T686A Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7LQDA 1.95 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YB4, TOE Type1, Allosteric 519 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP5A 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7RO, 1KA Type1, Type1 519 - 794 0 None S611G Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 6TNBA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno 8QW Type1.5_Front 517 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5N9SA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo 8QW Type1.5_Front 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN AF-P33981-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 517 - 799 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN AF-P33981-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 517 - 799 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3H9FA 2.6 Inactive DFGin‑BLAplus in-none out-out nonTYR APEdihe_aaoni APEdist_nnno 92M Type1 519 - 794 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 7CHMA 2.65 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo FZF Type1 516 - 794 0 TPO675,TPO686 None Dual specificity protein kinase TTK
OTHER UHMK1 UHMK1_HUMAN AF-Q8TAS1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 312 0 None None Serine/threonine-protein kinase Kist
OTHER UHMK1 UHMK1_HUMAN AF-Q8TAS1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 312 0 None None Serine/threonine-protein kinase Kist
OTHER ULK1 ULK1_HUMAN AF-O75385-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 286 0 None None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN AF-O75385-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 286 0 None None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5GA 2.019 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5GB 2.019 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 279 0 TPO180 None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5HA 1.941 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5HB 1.941 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5IA 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5IB 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5IC 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5ID 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5JA 2.164 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYT Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5JB 2.164 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYT Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5KA 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5KB 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5KC 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5KD 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5LA 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5LB 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 6MNHA 1.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo JVD Type1 8 - 290 0 SEP87 S195A,S224A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8SV9A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WXH Type1 8 - 281 0 SEP87,TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8SV9B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WXH Type1 8 - 281 0 SEP87,TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 4WNOA 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RF Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 4WNPA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 7 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 4WNPB 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 4WNPC 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 279 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 4WNPD 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 5CI7A 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 51W Type1 3 - 279 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 6QASA 1.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34W Type1 8 - 281 0 SEP87,TPO180 None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 6QASB 1.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34W, 34W Type1, Allosteric 8 - 280 0 SEP87,TPO180 None Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 9F32A 2.1 Inactive None‑None none-none none-out nonTYR APEdihe_aaioi APEdist_nnno A1H9M Type1 8 - 282 0 None None Serine/threonine-protein kinase ULK1
OTHER ULK2 ULK2_HUMAN AF-Q8IYT8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN AF-Q8IYT8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QATA 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QATB 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QATC 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QATD 2.77 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 270 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAUA 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 1FV Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAUC 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanno APEdist_nnnn 1FV Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAVA 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo HVH Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAVB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooo HVH Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAVC 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oooo HVH Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAVD 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo HVH Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6YIDA 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6YIDB 2.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanno APEdist_nnnn EDJ Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6YIDC 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aanni APEdist_nnnn EDJ Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6YIDD 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK3 ULK3_HUMAN AF-Q6PHR2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 278 0 None None Serine/threonine-protein kinase ULK3
OTHER ULK3 ULK3_HUMAN AF-Q6PHR2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 278 0 None None Serine/threonine-protein kinase ULK3
OTHER ULK3 ULK3_HUMAN 6FDYU 1.7 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii DB8, DB8 Type1, Allosteric 9 - 274 0 None None Serine/threonine-protein kinase ULK3
OTHER ULK3 ULK3_HUMAN 6FDZU 2.55 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo C87 Type1 8 - 274 0 None None Serine/threonine-protein kinase ULK3
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4
OTHER WEE1 WEE1_HUMAN 9D0SA 1.64 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1R Type1 292 - 574 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 8WDKW 3.64 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 293 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN AF-P30291-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 291 - 577 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN AF-P30291-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 291 - 577 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 2Z2WA 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 770 Type1 291 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 7N3UA 2.65 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi 05J Type1 293 - 570 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 8BJUA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi QT9 Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 2IN6A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 839 Type1 291 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 2IO6A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 330 Type1 291 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 3BI6A 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 396 Type1 293 - 570 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 3BIZA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 61E Type1 293 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 3CQEA 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi P91 Type1 293 - 570 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 3CR0A 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 809 Type1 293 - 573 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5V5YA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 293 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VC3A 1.97 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi DB8 Type1 293 - 570 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VC4A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VC5A 1.93 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 96M Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VC6A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi P48 Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD2A 2.05 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi 34W Type1 293 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD4A 2.02 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99J Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD5A 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99M Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD7A 2.08 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99V Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD8A 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 98M Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VD9A 1.87 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 98G Type1 292 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 5VDAA 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 98D Type1 293 - 571 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 1X8BA 1.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 824 Type1 291 - 569 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 9D0QA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1S Type1 291 - 573 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 9D0QB 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1S Type1 291 - 574 0 None None Wee1-like protein kinase
OTHER WEE1 WEE1_HUMAN 9D0RA 2.34 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1T Type1 292 - 574 0 None None Wee1-like protein kinase
OTHER WEE2 WEE2_HUMAN AF-P0C1S8-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 204 - 494 0 None None Wee1-like protein kinase 2
OTHER WEE2 WEE2_HUMAN AF-P0C1S8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 204 - 494 0 None None Wee1-like protein kinase 2
OTHER WEE2 WEE2_HUMAN 5VDKA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 204 - 486 0 None None Wee1-like protein kinase 2
OTHER WNK1 WNK1_HUMAN 5WDYA 2.458 None DFGin‑BLAminus out-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP, A6S ATPlike, Type3 208 - 481 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 5WDYB 2.458 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, A6S ATPlike, Type3 206 - 480 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 5WE8A 2.006 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaioo APEdist_oooo ANP, A7Y ATPlike, Type3 209 - 483 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 5WE8B 2.006 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaiio APEdist_oooo ANP, A7Y ATPlike, Type3 207 - 480 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN AF-Q9H4A3-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 212 - 487 0 None None Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN AF-Q9H4A3-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 212 - 487 0 None None Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 5TF9A 2.5 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaioo APEdist_nnno 7AV, ANP Type3, ATPlike 210 - 483 0 None None Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 5TF9B 2.5 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaiio APEdist_nnno 7AV, ANP Type3, ATPlike 206 - 480 0 None None Serine/threonine-protein kinase WNK1
OTHER WNK1 WNK1_HUMAN 4PWNA 1.84 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 210 - 482 0 None None Serine/threonine-protein kinase WNK1
OTHER WNK2 WNK2_HUMAN AF-Q9Y3S1-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 186 - 461 0 None None Serine/threonine-protein kinase WNK2
OTHER WNK2 WNK2_HUMAN AF-Q9Y3S1-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 186 - 461 0 None None Serine/threonine-protein kinase WNK2
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN AF-Q9BYP7-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN AF-Q9BYP7-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O21A 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 407 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O21B 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 8EDHC 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 136 - 407 0 None S308A Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 9D7QA 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 130 - 407 0 None E314A Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 9D7QB 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 132 - 407 0 None E314A Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 8EDHA 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn WGK Type1 137 - 406 0 None S308A Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O2BA 2.038 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_nnoo KS1 Type1 132 - 414 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O23A 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 136 - 405 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O23B 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 132 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK4 WNK4_HUMAN AF-Q96J92-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 440 0 None None Serine/threonine-protein kinase WNK4
OTHER WNK4 WNK4_HUMAN AF-Q96J92-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 440 0 None None Serine/threonine-protein kinase WNK4

OTHER / All / All

Total number of chains: 930
Active chains: 219
Total number of genes: 87
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 496 53.3% AF-Q2M2I8-K1A
DFGin ABAminus 130 14.0% AF-Q504Y2-K3A
DFGin None 85 9.1% 5GZAA
DFGin BLBminus 72 7.7% 5O1VA
None None 51 5.5% 4IX3A
DFGin BLBplus 36 3.9% 5UV4A
DFGout None 30 3.2% 4I93A
DFGin BLAplus 10 1.1% 7JXUA
DFGout BBAminus 8 0.9% 6FDZU
DFGin BLBtrans 6 0.6% 5DRBA
DFGinter None 5 0.5% 7MXJA
DFGinter BABtrans 1 0.1% 7QWKH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I92A 1.6 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93A 1.5 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93B 1.5 Pseudo DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAA 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAB 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAC 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAD 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4A 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4B 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4C 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4D 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER T1N2412 Q94K14_ARATH 8K20B 3.7 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 14 - 221 0 None None non-specific serine/threonine protein kinase Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TB 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TE 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TH 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TK 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TN 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5UB 3.9 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaooi APEdist_iiii No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5VB 4.25 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoii APEdist_iiii No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J6IB 3.7 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaooi APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5WB 3.7 Inactive DFGin‑BLAplus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 15 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER YABT PKN1_BACSU 6G4JA 1.599 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase YabT Bacillus subtilis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPA 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPB 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMB 2.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOB 2.502 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOD 2.502 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PKNG Q8NM29_CORGL 7MXBA 2.2 Inactive DFGin‑None out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MAP Type1 52 - 728 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXJA 1.92 Inactive DFGinter‑None out-out in-out nonTYR APEdihe_aaiii APEdist_ioii MAP Type1 62 - 358 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXKA 1.99 Inactive DFGinter‑None out-out in-out nonTYR APEdihe_aaiii APEdist_ioii MAP Type1 63 - 360 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXBB 2.2 Inactive DFGinter‑None out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MAP Type1 54 - 727 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
OTHER POMK SG196_DANRE 5GZAA 2.0 Pseudo DFGin‑None none-na in-out nonTYR APEdihe_aaioo APEdist_iioo ADP, ZZ1 ATPlike, Allosteric 53 - 342 0 None None Protein O-mannose kinase Danio rerio
OTHER BUBR1 A1Z6I7_DROME 6JKMA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo ADP ATPlike 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER BUBR1 A1Z6I7_DROME 6JKKA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER AAK1 AAK1_HUMAN AF-Q2M2I8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 321 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN AF-Q2M2I8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 321 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 4WSQA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 29 - 345 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 4WSQB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 33 - 342 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 8GMCA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 34 - 330 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 8GMCB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 31 - 330 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 8GMDA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRR Type1 34 - 329 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 8GMDB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRR Type1 29 - 330 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 9QB5A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F7I Type1 29 - 343 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 9QB5B 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F7I Type1 34 - 342 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 5L4QA 1.97 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LKB Type1 33 - 335 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 5L4QB 1.97 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LKB Type1 33 - 333 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER AAK1 AAK1_HUMAN 5TE0A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XIN Type1 27 - 345 0 None None AP2-associated protein kinase 1 Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3OA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3OB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDV Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3RA 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5I3RB 2.4 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IDK Type1 42 - 343 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 5IKWA 2.41 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6BU Type1 42 - 338 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN AF-Q9NSY1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 43 - 325 0 None None BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN AF-Q9NSY1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 43 - 325 0 None None BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 4W9XA 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3JW Type1 39 - 342 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BMP2K BMP2K_HUMAN 4W9WA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YDJ, YDJ Type1, Allosteric 39 - 344 0 None K320A,K321A BMP-2-inducible protein kinase Homo sapiens
OTHER BUB1 BUB1_HUMAN 4QPMA 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 4QPMB 2.202 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 740 - 1081 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 4R8QA 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iooo ADP ATPlike 736 - 1083 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 5DMZA 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 5DMZB 2.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iooi ADP ATPlike 735 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN AF-O43683-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 779 - 1064 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN AF-O43683-K3A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 779 - 1064 0 None None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER BUB1 BUB1_HUMAN 6F7BA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoio APEdist_iioo CVQ Type1 733 - 1083 0 SEP969 None Mitotic checkpoint serine/threonine-protein kinase BUB1 Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F99A 2.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AA 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9AC 2.17 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn ADP ATPlike 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA7A 1.67 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP ATPlike 39 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA8A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni ADP, BEF ATPlike, Allosteric 38 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN AF-O00311-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN AF-O00311-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 50 - 574 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9BA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 39 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9BC 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SY Type1 37 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 4F9CA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnnn 0SX Type1 41 - 572 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CDC7 CDC7_HUMAN 6YA6A 1.44 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni 0SX, BO3 Type1, Type1 38 - 573 0 None None Cell division cycle 7-related protein kinase Homo sapiens
OTHER CHUK IKKA_HUMAN AF-O15111-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN AF-O15111-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZA 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZB 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZC 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZD 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZE 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZF 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZG 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZH 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZI 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZJ 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZK 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5EBZL 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQWA 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQWB 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQXA 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQXB 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQYA 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER CHUK IKKA_HUMAN 5TQYB 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
OTHER DSTYK DUSTY_HUMAN AF-Q6XUX3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 644 - 916 0 None None Dual serine/threonine and tyrosine protein kinase Homo sapiens
OTHER DSTYK DUSTY_HUMAN AF-Q6XUX3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 644 - 916 0 None None Dual serine/threonine and tyrosine protein kinase Homo sapiens
OTHER EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 159 - 591 0 None None Eukaryotic translation initiation factor 2-alpha kinase 1 Homo sapiens
OTHER EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 159 - 591 0 None None Eukaryotic translation initiation factor 2-alpha kinase 1 Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19B 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A19C 2.5 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 2A1AB 2.8 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo No_ligand No_ligand 258 - 541 0 TPO446 H412N,C551A Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 8QELB 2.451 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo UH3 Type1 258 - 541 0 TPO446 None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn ADP ATPlike 256 - 544 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn ADP ATPlike 255 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3KC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ADP ATPlike 257 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN AF-P19525-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 259 - 546 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN AF-P19525-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 259 - 546 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 6D3LA 3.1 Inactive DFGin‑None in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 258 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 3UIUA 2.903 Inactive DFGin‑None in-none in-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 254 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK2 E2AK2_HUMAN 3UIUB 2.903 Inactive DFGin‑None in-none in-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 254 - 541 0 None None Interferon-induced, double-stranded RNA-activated protein kinase Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN AF-Q9NZJ5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 585 - 1085 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN AF-Q9NZJ5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 585 - 1085 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7OA 2.65 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z6 Type1 585 - 1081 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 7MF0AAA 2.809 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn Z6P Type1 586 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 8EQ9AAA 2.86 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn WPB Type1 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 8EQDAAA 2.92 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WPX Type1 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4G31A 2.28 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 0WH Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4G34A 2.7 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 924 Type1.5_Back 588 - 1079 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4M7IA 2.34 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 27D Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 8EQEAAA 2.559 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WQ2 Type1.5_Back 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7JA 2.3 Inactive DFGout‑BBAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 3Z1 Type1 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7KA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z3 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7LA 1.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z4 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7HA 2.0 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 3Z2 Type2 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN AF-Q9P2K8-K2A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 582 - 1009 0 None None eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN AF-Q9P2K8-K4A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 582 - 1009 0 None None eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3NA 3.01 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA4 Type1 584 - 1003 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3OA 2.4 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA7 Type1.5_Back 584 - 1004 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6A 2.8 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 38O Type1 584 - 1004 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6B 2.8 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_oooo 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6C 2.8 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QQ6D 2.8 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 38O Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKH 2.3 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaoni APEdist_oooo G41 Type1 584 - 1006 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKF 2.3 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaoni APEdist_oooo G41 Type1 584 - 1005 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKA 2.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 998 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKB 2.3 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 998 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKC 2.3 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aanni APEdist_nnnn G41 Type1 583 - 1004 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKD 2.3 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aaoni APEdist_nnno G41 Type1 583 - 1003 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKE 2.3 Inactive DFGout‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn G41 Type1 584 - 1004 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 7QWKG 2.3 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aanni APEdist_nnnn G41 Type1 584 - 1007 0 None D848N eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LA 2.61 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aanni APEdist_nnnn KAV Type2 584 - 1002 0 None K807A,D848N,T899A,T904A eIF-2-alpha kinase GCN2 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3LB 2.61 Inactive DFGout‑None in-in none-none nonTYR APEdihe_aanni APEdist_nnnn KAV Type2 584 - 1002 0 None K807A,D848N,T899A,T904A eIF-2-alpha kinase GCN2 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4Z7HB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioi 4L5 Type1 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN AF-O75460-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 561 - 840 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN AF-O75460-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 561 - 840 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 5HGIA 2.584 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDFB 2.54 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnio No_ligand No_ligand 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3BA 2.57 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3CA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3CB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3CC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3CD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZCA 2.494 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZCB 2.494 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 562 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9GOWA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9GOWB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9GOWC 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9GOWD 3.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii A1IOO Type1 562 - 964 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3KA 2.08 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii SJS Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3EB 2.737 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaooi APEdist_nnoo SJV Type1.5_Back 563 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDFA 2.54 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N94 Type1.5_Back 560 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 7BMKA 1.85 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi U4N Type1.5_Back 561 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 7BMKB 1.85 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_ioio U4N Type1.5_Back 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6URCA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6URCB 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDDB 2.4 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N97 Type1.5_Back 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4U6RA 2.5 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi 3E4 Type1.5_Back 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDBA 2.45 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N8S Type1.5_Back 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3EA 2.737 Inactive DFGin‑BLAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn SJV Type1.5_Front 562 - 962 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDDA 2.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiio APEdist_oiio N97 Type1.5_Front 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 8UVLA 2.43 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi XOE Type1.5_Front 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDA 3.102 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDB 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZDC 3.102 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_niii ADP ATPlike 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23A 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23B 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoi ADP ATPlike 564 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23C 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_iioi ADP ATPlike 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 3P23D 2.7 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoi ADP ATPlike 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9N88A 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 9N88E 2.6 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 563 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W39A 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W39B 1.736 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoo APEdist_nnnn SJG Type1 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3AA 2.606 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3AB 2.606 Inactive DFGin‑BLBplus in-out none-out nonTYR APEdihe_aaooo APEdist_nnno SJM Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4Z7GA 2.6 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4Z7GB 2.6 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 562 - 962 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4Z7HA 2.9 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 4L5 Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9A 2.463 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9B 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 4K7 Type3 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9C 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6HX1A 2.14 Inactive None‑None none-none out-out nonTYR APEdihe_aaooi APEdist_iioo GXK Type1 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6HV0A 2.73 Inactive None‑None none-none out-out nonTYR APEdihe_aaoii APEdist_iioo GUK Type1 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN2 ERN2_HUMAN AF-Q76MJ5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 510 - 789 0 None None Serine/threonine-protein kinase/endoribonuclease IRE2 Homo sapiens
OTHER ERN2 ERN2_HUMAN AF-Q76MJ5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 510 - 789 0 None None Serine/threonine-protein kinase/endoribonuclease IRE2 Homo sapiens
OTHER GAK GAK_HUMAN 4O38A 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 25 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4O38B 2.097 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 26 - 337 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y7ZA 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y7ZB 2.804 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRE Type1 25 - 335 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 5Y80A 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo IRE, IRE Type1, Allosteric 25 - 332 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN AF-O14976-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 323 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN AF-O14976-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 32 - 323 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4Y8DA 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4Y8DB 2.1 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 49J Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN AF-Q8TF76-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN AF-Q8TF76-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 2WB8A 2.15 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 447 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 5HTBA 1.7 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 5HTCA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9B2SK 3.01 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9B2UK 3.64 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G39A 1.45 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605Y Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 2VUWA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLTA 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDF Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 3E7VA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DZO Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 3F2NA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IZZ Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 3FMDA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IQB Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 3IQ7A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 4OUCA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 4QTCA 1.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 38Z Type1 469 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G34A 1.76 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G35A 1.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKK Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G36A 1.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKH Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G37A 1.48 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa FTU Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G38A 1.47 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBN Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z57A 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8W Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z58A 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q9B Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z59A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q98 Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5CA 1.75 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa PQ5 Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5DA 1.75 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8Q Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5EA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8K Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 7AVQA 1.65 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa S1Z Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 7OPSA 2.38 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 07C Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 8RDKA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa YQT Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLBA 2.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDB Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLOA 2.9 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDC Type1 466 - 797 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLQA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDD Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLRA 1.91 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDE Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 7SQMA 1.78 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A5G Type1 453 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6G3AA 1.43 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605T Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z56A 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5BA 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLCA 2.18 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9B2TK 2.99 Inactive DFGin‑None out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER IKBKB IKKB_HUMAN AF-O14920-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 316 0 None None Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN AF-O14920-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 316 0 None None Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CB 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iooo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CC 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CD 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CF 3.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVC 4.16 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 12 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVD 4.16 Inactive DFGin‑BLAminus in-out out-out nonTYR APEdihe_aaioo APEdist_niio No_ligand No_ligand 6 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4KIKA 2.83 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo KSA Type1 9 - 663 0 SEP257 None Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4KIKB 2.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KSA Type1 2 - 663 0 SEP177,SEP181 None Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVB 4.16 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 8 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CA 3.98 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 4E3CE 3.98 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 16 - 665 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVE 4.16 Inactive DFGinter‑None in-out out-out nonTYR APEdihe_aaooi APEdist_iiio No_ligand No_ligand 9 - 643 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVA 4.16 Inactive None‑None in-in out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 8 - 666 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER IKBKE IKKE_HUMAN AF-Q14164-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Inhibitor of nuclear factor kappa-B kinase subunit epsilon Homo sapiens
OTHER IKBKE IKKE_HUMAN AF-Q14164-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Inhibitor of nuclear factor kappa-B kinase subunit epsilon Homo sapiens
OTHER MLKL MLKL_HUMAN 6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MOS MOS_HUMAN AF-P00540-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 346 0 None None Proto-oncogene serine/threonine-protein kinase mos Homo sapiens
OTHER MOS MOS_HUMAN AF-P00540-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 52 - 346 0 None None Proto-oncogene serine/threonine-protein kinase mos Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PBK TOPK_HUMAN AF-Q96KB5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 24 - 322 0 None None Lymphokine-activated killer T-cell-originated protein kinase Homo sapiens
OTHER PBK TOPK_HUMAN AF-Q96KB5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 24 - 322 0 None None Lymphokine-activated killer T-cell-originated protein kinase Homo sapiens
OTHER PBK TOPK_HUMAN 5J0AA 2.74 Inactive DFGin‑BLBtrans out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 23 - 320 0 None T198E Lymphokine-activated killer T-cell-originated protein kinase Homo sapiens
OTHER PBK TOPK_HUMAN 5J0AB 2.74 Inactive DFGin‑BLBtrans out-out in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 19 - 319 0 None T198E Lymphokine-activated killer T-cell-originated protein kinase Homo sapiens
OTHER PDIK1L PDK1L_HUMAN AF-Q8N165-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 339 0 None None Serine/threonine-protein kinase PDIK1L Homo sapiens
OTHER PDIK1L PDK1L_HUMAN AF-Q8N165-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 339 0 None None Serine/threonine-protein kinase PDIK1L Homo sapiens
OTHER PEAK1 PEAK1_HUMAN 6BHCA 2.3 Pseudo DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaoai APEdist_nnno No_ligand No_ligand 1285 - 1743 0 None S1542T Inactive tyrosine-protein kinase PEAK1 Homo sapiens
OTHER PIK3R4 A0JP11_HUMAN 9ZPDA 3.38 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 A0JP11_HUMAN 9ZPCA 3.83 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9C82A 6.84 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 64 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 7BL1CCC 9.8 Pseudo None‑None out-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 12 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHHA 4.5 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 16 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PINK1 PINK1_HUMAN AF-Q9BXM7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 148 - 517 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN AF-Q9BXM7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 148 - 517 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9EIHA 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9EIHB 3.1 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9EIIB 2.75 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9EIJB 3.3 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 63 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9KOXC 4.43 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 156 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9KQNC 2.84 Inactive None‑None none-none none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 305 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PINK1 PINK1_HUMAN 9KMRC 2.98 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 156 - 581 0 None None Serine/threonine-protein kinase PINK1, mitochondrial Homo sapiens
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K3A -1.0 Active DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC Homo sapiens
OTHER PKDCC PKDCC_HUMAN AF-Q504Y2-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 130 - 399 0 None None Extracellular tyrosine-protein kinase PKDCC Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN AF-Q99640-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 102 - 367 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN AF-Q99640-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 102 - 367 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 3P1AA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi No_ligand No_ligand 76 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8ZTXA 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D83 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGVB 2.041 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8ZU2A 1.799 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D85 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8ZUDA 1.505 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D82 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8ZULA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oooi A1D84 Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGLA 2.17 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJW Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGLB 2.17 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJW Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCVA 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 1N1 Type1 75 - 361 0 TPO260 None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCWA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 93J Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCWB 2.25 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 93J Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCXA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi H8H Type1 75 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCYA 1.56 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi DB8 Type1 77 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VCZA 1.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VD0A 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VD1A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi P48 Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 5VD3A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi H8H Type1 78 - 360 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6CA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGR Type1 78 - 362 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6CB 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGR Type1 77 - 360 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6DB 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6EB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8WJYA 1.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nooi W9X Type1 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9M6PAAA 2.383 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_nnoi A1EMX Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGVA 2.041 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LIDA 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LIDB 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGNA 2.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGNB 2.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6DA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6EA 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6FA 2.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6FB 2.49 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9M6PBBB 2.383 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii A1EMX Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PRAG1 PRAG1_HUMAN 5VE6A 2.953 Pseudo None‑None none-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 944 - 1405 0 None None Inactive tyrosine-protein kinase PRAG1 Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER SBK1 SBK1_HUMAN AF-Q52WX2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 45 - 323 0 None None Serine/threonine-protein kinase SBK1 Homo sapiens
OTHER SBK1 SBK1_HUMAN AF-Q52WX2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 45 - 323 0 None None Serine/threonine-protein kinase SBK1 Homo sapiens
OTHER SBK2 SBK2_HUMAN AF-P0C263-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iioi No_ligand No_ligand 54 - 335 0 None None Serine/threonine-protein kinase SBK2 Homo sapiens
OTHER SBK2 SBK2_HUMAN AF-P0C263-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 54 - 335 0 None None Serine/threonine-protein kinase SBK2 Homo sapiens
OTHER SBK3 SBK3_HUMAN AF-P0C264-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iioi No_ligand No_ligand 35 - 314 0 None None Uncharacterized serine/threonine-protein kinase SBK3 Homo sapiens
OTHER SBK3 SBK3_HUMAN AF-P0C264-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 35 - 314 0 None None Uncharacterized serine/threonine-protein kinase SBK3 Homo sapiens
OTHER STK16 STK16_HUMAN AF-O75716-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 300 0 None None Serine/threonine-protein kinase 16 Homo sapiens
OTHER STK16 STK16_HUMAN AF-O75716-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 300 0 None None Serine/threonine-protein kinase 16 Homo sapiens
OTHER STK16 STK16_HUMAN 2BUJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, STU Type1, Allosteric 13 - 299 0 None R19H,R266W Serine/threonine-protein kinase 16 Homo sapiens
OTHER STK16 STK16_HUMAN 2BUJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, STU Type1, Type1 13 - 297 0 None R19H,R266W Serine/threonine-protein kinase 16 Homo sapiens
OTHER STK35 STK35_HUMAN AF-Q8TDR2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 534 0 None None Serine/threonine-protein kinase 35 Homo sapiens
OTHER STK35 STK35_HUMAN AF-Q8TDR2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 194 - 534 0 None None Serine/threonine-protein kinase 35 Homo sapiens
OTHER STK36 STK36_HUMAN AF-Q9NRP7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 262 0 None None Serine/threonine-protein kinase 36 Homo sapiens
OTHER STK36 STK36_HUMAN AF-Q9NRP7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 262 0 None None Serine/threonine-protein kinase 36 Homo sapiens
OTHER TBK1 TBK1_HUMAN AF-Q9UHD2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN AF-Q9UHD2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 312 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4EUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 307 0 SEP172 D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4EUUB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 307 0 SEP172 D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4EUTA 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo BX7 Type1 2 - 385 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4EUTB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo BX7 Type1 2 - 385 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IW0A 4.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 657 0 SEP172 D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6O8BA 3.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_oiii BX7 Type1 2 - 656 0 None D135N,S172E Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6O8BB 3.4 Inactive DFGin‑BLAminus in-in out-in nonTYR APEdihe_aaiii APEdist_iiii BX7 Type1 2 - 654 0 None D135N,S172E Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6NT9A 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6NT9B 3.3 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 658 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 5W5VA 3.645 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn ANW Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6BODA 3.197 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn E0P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6RSTA 3.29 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHQ Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IWOA 2.61 Inactive DFGin‑BLBplus out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1H4 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM2A 2.5 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IM3A 3.342 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn BX7 Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6BNYA 3.341 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn E0M Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6BOEA 3.598 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aaiii APEdist_nnni E0S Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6CQ0A 3.19 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_nnno F8M Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6CQ4A 3.2 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aaiii APEdist_nnni F8P Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6CQ5A 3.354 Inactive DFGin‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn F8S Type1 1 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6RSRA 3.15 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KHT Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 6RSUA 2.75 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni KJB Type1 2 - 657 0 None None Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IWPA 3.065 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni BX7 Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IWQA 3.0 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1FV Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TLK1 TLK1_HUMAN AF-Q9UKI8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 448 - 742 0 None None Serine/threonine-protein kinase tousled-like 1 Homo sapiens
OTHER TLK1 TLK1_HUMAN AF-Q9UKI8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 448 - 742 0 None None Serine/threonine-protein kinase tousled-like 1 Homo sapiens
OTHER TLK2 TLK2_HUMAN 5O0YA 2.86 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 456 - 743 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
OTHER TLK2 TLK2_HUMAN AF-Q86UE8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
OTHER TLK2 TLK2_HUMAN AF-Q86UE8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 454 - 749 0 None None Serine/threonine-protein kinase tousled-like 2 Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN AF-Q96S44-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 25 - 253 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN AF-Q96S44-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 25 - 253 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 9FL9B 3.74 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZAA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DUI Type1 14 - 246 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZAC 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DUI Type1 18 - 245 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZBA 2.02 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DQ4 Type1 14 - 245 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZBC 2.02 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DQ4 Type1 18 - 245 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZCA 1.71 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DO0 Type1 18 - 246 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZCC 1.71 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DO0 Type1 18 - 246 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZDA 2.05 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DVO Type1 18 - 249 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 7SZDC 2.05 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DVO Type1 18 - 249 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TTK TTK_HUMAN 3HMNA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo ATP ATPlike 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3CEKA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3DBQA 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo No_ligand No_ligand 515 - 796 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2ZMCA 3.14 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6GVJA 2.41 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 515 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5LJJA 3.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo AD5 Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5MRBA 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 795 0 None C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EH0A 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5NW Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6H3KA 2.48 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn FMW Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4JS8A 1.94 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo 1PF Type1 515 - 793 0 TPO675,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4JT3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1PH Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4O6LA 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4O6LB 2.38 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 2QK Type1 515 - 793 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4ZEGA 2.33 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 052 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CILA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo FZR Type1 515 - 795 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CHNA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo FZL Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CJAA 2.49 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo G0U Type1 515 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CLHA 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo G5C Type1 516 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TN9A 2.6 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnoo NN5 Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNCA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo O23 Type1 516 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6N6OA 2.6 Inactive DFGin‑ABAminus out-out out-none nonTYR APEdihe_aanni APEdist_nnnn KE7 Type1 515 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BHZA 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0B Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI0A 2.84 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z0W Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI1A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO6 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4BI2A 3.11 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo ZO8 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4EA 2.6 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 4T9 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4FA 2.36 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo 7CE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4GA 2.65 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaono APEdist_nnoo 7RO Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4HA 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 7RO Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4IA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn X20 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4C4JA 2.5 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaini APEdist_nnoo X21 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CV8A 3.0 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno 3D7 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CV9A 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo W2K Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 4CVAA 2.5 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo WBI Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP0A 2.15 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo AU5 Type1 519 - 795 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP1A 2.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnoo O38 Type1 519 - 795 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP2A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno PWU Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHLA 2.66 Inactive DFGin‑ABAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo 0SQ Type1 519 - 796 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHOA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O1 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EHYA 2.26 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5O4 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI2A 2.67 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 5O7 Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI6A 2.01 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_oooo 5OQ Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5EI8A 2.17 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo 5OE Type1 519 - 753 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N87A 2.29 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo N66 Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP6A 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo PWU Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5O91A 3.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo C5N Type1 519 - 796 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6B4WA 2.9 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnoo CQ7 Type1 515 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3VQUA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno O22 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WYXA 2.9 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O38 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WYYA 3.05 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno O17 Type1 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N7VA 2.52 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaono APEdist_oooo 8PT Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N84A 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo 8Q5 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N93A 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnoo 8QE Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NA0A 2.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_nnoo 8QZ Type1 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3HMOA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 514 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3HMPA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo CX4 Type1 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP3A 2.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_iooo AU5 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP4A 2.85 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nooo O38 Type1 519 - 794 0 TPO686 S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2ZMDA 2.88 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaoni APEdist_oooo 537 Type1 516 - 795 0 None T686A Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7LQDA 1.95 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YB4, TOE Type1, Allosteric 519 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP5A 2.8 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7RO, 1KA Type1, Type1 519 - 794 0 None S611G Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 6TNBA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno 8QW Type1.5_Front 517 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5N9SA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo 8QW Type1.5_Front 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN AF-P33981-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi No_ligand No_ligand 517 - 799 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN AF-P33981-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 517 - 799 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3H9FA 2.6 Inactive DFGin‑BLAplus in-none out-out nonTYR APEdihe_aaoni APEdist_nnno 92M Type1 519 - 794 0 TPO675,TPO676,SEP677 None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 7CHMA 2.65 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaoni APEdist_nnoo FZF Type1 516 - 794 0 TPO675,TPO686 None Dual specificity protein kinase TTK Homo sapiens
OTHER UHMK1 UHMK1_HUMAN AF-Q8TAS1-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 312 0 None None Serine/threonine-protein kinase Kist Homo sapiens
OTHER UHMK1 UHMK1_HUMAN AF-Q8TAS1-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 312 0 None None Serine/threonine-protein kinase Kist Homo sapiens
OTHER ULK1 ULK1_HUMAN AF-O75385-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 286 0 None None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN AF-O75385-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 286 0 None None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5GA 2.019 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5GB 2.019 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 279 0 TPO180 None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5HA 1.941 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5HB 1.941 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XBJ Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5IA 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5IB 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5IC 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5ID 1.829 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYX Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5JA 2.164 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYT Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5JB 2.164 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WYT Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5KA 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5KB 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5KC 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 279 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5KD 2.209 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HVH Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5LA 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5LB 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 6MNHA 1.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooo JVD Type1 8 - 290 0 SEP87 S195A,S224A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8SV9A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WXH Type1 8 - 281 0 SEP87,TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8SV9B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WXH Type1 8 - 281 0 SEP87,TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 4WNOA 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RF Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 4WNPA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 7 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 4WNPB 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 4WNPC 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 279 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 4WNPD 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3RJ Type1 8 - 280 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 5CI7A 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 51W Type1 3 - 279 0 TPO180 E37A,K38A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 6QASA 1.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34W Type1 8 - 281 0 SEP87,TPO180 None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 6QASB 1.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34W, 34W Type1, Allosteric 8 - 280 0 SEP87,TPO180 None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 9F32A 2.1 Inactive None‑None none-none none-out nonTYR APEdihe_aaioi APEdist_nnno A1H9M Type1 8 - 282 0 None None Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK2 ULK2_HUMAN AF-Q8IYT8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN AF-Q8IYT8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QATA 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QATB 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QATC 2.77 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QATD 2.77 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn FE7 Type1 1 - 270 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUA 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 1FV Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUC 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanno APEdist_nnnn 1FV Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAVA 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo HVH Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAVB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oooo HVH Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAVC 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_oooo HVH Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAVD 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo HVH Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6YIDA 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6YIDB 2.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanno APEdist_nnnn EDJ Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6YIDC 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aanni APEdist_nnnn EDJ Type1 1 - 272 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6YIDD 2.7 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK3 ULK3_HUMAN AF-Q6PHR2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 278 0 None None Serine/threonine-protein kinase ULK3 Homo sapiens
OTHER ULK3 ULK3_HUMAN AF-Q6PHR2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 278 0 None None Serine/threonine-protein kinase ULK3 Homo sapiens
OTHER ULK3 ULK3_HUMAN 6FDYU 1.7 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii DB8, DB8 Type1, Allosteric 9 - 274 0 None None Serine/threonine-protein kinase ULK3 Homo sapiens
OTHER ULK3 ULK3_HUMAN 6FDZU 2.55 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo C87 Type1 8 - 274 0 None None Serine/threonine-protein kinase ULK3 Homo sapiens
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER WEE1 WEE1_HUMAN 9D0SA 1.64 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1R Type1 292 - 574 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 8WDKW 3.64 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 293 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN AF-P30291-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 291 - 577 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN AF-P30291-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 291 - 577 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 2Z2WA 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 770 Type1 291 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 7N3UA 2.65 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi 05J Type1 293 - 570 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 8BJUA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi QT9 Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 2IN6A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 839 Type1 291 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 2IO6A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 330 Type1 291 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 3BI6A 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 396 Type1 293 - 570 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 3BIZA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 61E Type1 293 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 3CQEA 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi P91 Type1 293 - 570 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 3CR0A 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 809 Type1 293 - 573 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5V5YA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 293 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VC3A 1.97 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi DB8 Type1 293 - 570 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VC4A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VC5A 1.93 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 96M Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VC6A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi P48 Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD2A 2.05 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiai APEdist_iooi 34W Type1 293 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD4A 2.02 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99J Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD5A 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99M Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD7A 2.08 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 99V Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD8A 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 98M Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VD9A 1.87 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 98G Type1 292 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VDAA 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi 98D Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 1X8BA 1.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 824 Type1 291 - 569 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 9D0QA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1S Type1 291 - 573 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 9D0QB 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1S Type1 291 - 574 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 9D0RA 2.34 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1A1T Type1 292 - 574 0 None None Wee1-like protein kinase Homo sapiens
OTHER WEE2 WEE2_HUMAN AF-P0C1S8-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 204 - 494 0 None None Wee1-like protein kinase 2 Homo sapiens
OTHER WEE2 WEE2_HUMAN AF-P0C1S8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 204 - 494 0 None None Wee1-like protein kinase 2 Homo sapiens
OTHER WEE2 WEE2_HUMAN 5VDKA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 8X7 Type1 204 - 486 0 None None Wee1-like protein kinase 2 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5WDYA 2.458 None DFGin‑BLAminus out-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP, A6S ATPlike, Type3 208 - 481 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5WDYB 2.458 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aanoo APEdist_nnnn ANP, A6S ATPlike, Type3 206 - 480 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5WE8A 2.006 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaioo APEdist_oooo ANP, A7Y ATPlike, Type3 209 - 483 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5WE8B 2.006 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaiio APEdist_oooo ANP, A7Y ATPlike, Type3 207 - 480 0 None S378D,E396A,E397A,K398A Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN AF-Q9H4A3-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 212 - 487 0 None None Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN AF-Q9H4A3-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 212 - 487 0 None None Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5TF9A 2.5 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaioo APEdist_nnno 7AV, ANP Type3, ATPlike 210 - 483 0 None None Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 5TF9B 2.5 Inactive DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaiio APEdist_nnno 7AV, ANP Type3, ATPlike 206 - 480 0 None None Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK1 WNK1_HUMAN 4PWNA 1.84 Inactive DFGin‑None out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 210 - 482 0 None None Serine/threonine-protein kinase WNK1 Homo sapiens
OTHER WNK2 WNK2_HUMAN AF-Q9Y3S1-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 186 - 461 0 None None Serine/threonine-protein kinase WNK2 Homo sapiens
OTHER WNK2 WNK2_HUMAN AF-Q9Y3S1-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 186 - 461 0 None None Serine/threonine-protein kinase WNK2 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN AF-Q9BYP7-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN AF-Q9BYP7-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 138 - 413 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O21A 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 407 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O21B 2.06 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiii APEdist_oiio No_ligand No_ligand 135 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 8EDHC 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 136 - 407 0 None S308A Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 9D7QA 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 130 - 407 0 None E314A Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 9D7QB 3.301 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 132 - 407 0 None E314A Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 8EDHA 3.111 Inactive DFGin‑BLAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn WGK Type1 137 - 406 0 None S308A Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O2BA 2.038 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_nnoo KS1 Type1 132 - 414 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O23A 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 136 - 405 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O23B 2.25 Inactive DFGin‑None out-na out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 132 - 408 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK4 WNK4_HUMAN AF-Q96J92-K1A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 440 0 None None Serine/threonine-protein kinase WNK4 Homo sapiens
OTHER WNK4 WNK4_HUMAN AF-Q96J92-K3A -1.0 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 165 - 440 0 None None Serine/threonine-protein kinase WNK4 Homo sapiens
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CLRA 3.706 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 2 - 407 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CLRB 3.706 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiii No_ligand No_ligand 2 - 403 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER TKUL E9B6S8_LEIMU 9GMPA 1.89 Inactive DFGin‑BLBplus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 647 - 921 0 None None Protein kinase domain-containing protein Leishmania mexicana
OTHER NFR5-12 Q70KR1_LOTJA 8S79A 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 280 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER NFR5-12 Q70KR1_LOTJA 8S79B 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 300 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER BUD32 KAE1B_METJA 8UNKB 2.91 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 356 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 9D85B 3.59 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 2VWBA 3.05 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Allosteric 1 - 530 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 2VWBB 3.05 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Allosteric 1 - 532 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3EN9A 2.67 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR Allosteric 1 - 534 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3EN9B 2.67 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR Allosteric 1 - 529 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3ENHA 3.6 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR, TBR, TBR Allosteric, Allosteric, Allosteric 1 - 534 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3ENHB 3.6 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR, TBR, TBR, TBR Allosteric, Allosteric, Allosteric, Allosteric 1 - 529 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 8UP5B 3.56 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER STT7 C1EBN1_MICCC 4IX3A 1.35 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX3B 1.35 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX4A 1.499 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX4B 1.499 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX5A 1.7 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX5B 1.7 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX6A 1.6 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX6B 1.6 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER AAK1 AAK1_MOUSE 7LVIA 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFY Type1 34 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVHA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFS Type1 34 - 328 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVHB 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 35 - 329 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVIB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 35 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ6A 2.132 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ6B 2.132 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5OI Type1 32 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ7A 2.124 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5P6 Type1 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ7B 2.124 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5P6 Type1 31 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ8A 2.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5QI, PG6 Type1, Allosteric 33 - 329 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ8B 2.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV, PG6 Type1, Allosteric 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER EIF2AK3 E2AK3_MOUSE 3QD2B 2.81 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aanoo APEdist_iiin No_ligand No_ligand 582 - 1078 0 TPO980 None Eukaryotic translation initiation factor 2-alpha kinase 3 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3A 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 560 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3B 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4A 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31K, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5A 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi 31L, ADP, PEU Allosteric, ATPlike, Allosteric 562 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER TBK1 TBK1_MOUSE 4JL9A 3.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno BX7 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 4JLCA 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno SU6 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CA 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn BX7 Type1 2 - 651 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CB 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoio APEdist_nnno BX7 Type1 2 - 653 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER PKNA PKNA_MYCTU 6B2QB 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo CJJ Type1 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QC 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno CJJ Type1 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QD 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nioo CJJ Type1 3 - 283 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QA 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno CJJ, 0BD Type1, Allosteric 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4OW8A 2.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 3 - 283 0 None None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FA 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 3 - 289 0 SEP46,TPO152,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FB 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 1 - 289 0 TPO21,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FC 2.9 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 289 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6B2PA 3.01 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn CJJ Type1 4 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMA 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnno MIX Type1 3 - 277 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMB 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_nnno MIX Type1 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMD 2.89 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioo APEdist_nnoo MIX Type1 3 - 277 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 5U94A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi G93 Type1.5_Back 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3OROA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooo APEdist_oioo AGS, NHE ATPlike, Allosteric 9 - 288 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMC 2.89 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn MIX Type1 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PA 2.37 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_iooo ACP ATPlike 1 - 278 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PB 2.37 Inactive None‑None in-out none-out nonTYR APEdihe_aanno APEdist_onnn ACP ATPlike 2 - 277 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F69A 2.8 Inactive None‑None in-out out-out nonTYR APEdihe_aanio APEdist_nnnn XDR Type1 3 - 287 0 TPO171 L33D,M145L,M155V Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F69B 2.8 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_nnoo XDR Type1 2 - 287 0 TPO171 L33D,M145L,M155V Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNE PKNE_MYCTU 2H34A 2.8 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 14 - 276 0 None None Serine/threonine-protein kinase PknE Mycobacterium tuberculosis
OTHER PKNE PKNE_MYCTU 2H34B 2.8 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 14 - 276 0 None None Serine/threonine-protein kinase PknE Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAA 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 3 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAB 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaini APEdist_nnno V17 Type1 3 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAC 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 24 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAD 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 4 - 277 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 7Q52AAA 2.35 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE, 8ZC Allosteric, Type1 87 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii AXX Type1 74 - 746 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIB 2.4 Inactive DFGin‑ABAminus out-out in-none nonTYR APEdihe_aaiii APEdist_niii AXX Type1 74 - 745 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y0XA 1.74 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii ADP ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y12A 1.9 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii AGS ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07A 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07B 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAA 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 260 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAB 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 257 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09A 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09B 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08A 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08B 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER FLS2 FLS2_ORYSJ 8JUPA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 861 - 1176 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER FLS2 FLS2_ORYSJ 8JUVA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 861 - 1178 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER PINK1 PINK1_PEDHC 6EQIC 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 147 - 574 0 SEP202,SEP204,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4KA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 117 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4KB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4LA 3.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 117 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4LB 3.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYFA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYFB 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MA 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MB 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MC 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MD 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4ME 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MF 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MG 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MH 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MI 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MJ 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MK 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4ML 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4NA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4NB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T3XA 3.53 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 119 - 573 0 None D334A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYB 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYG 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 157 - 559 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYH 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYA 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS, PE4 ATPlike, Allosteric 157 - 561 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER PK7 O96214_PLAFA 2PMLX 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 316 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER PK7 Q7YTF7_PLAF7 2PMNX 2.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K51 Type1 1 - 343 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER PK7 Q7YTF7_PLAF7 2PMOX 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HMD Type1 1 - 343 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXB 2.771 Pseudo DFGin‑BLAminus none-na in-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 909 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXA 2.771 Pseudo None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 914 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 9D3FA 2.0 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 211 - 482 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9A 1.8 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 480 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 4Q2AA 3.5 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 480 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9B 1.8 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 481 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 7UOSA 2.9 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo WIB Type1 211 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TA 2.01 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TB 2.01 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5DRBA 1.65 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioo APEdist_oooo 5FJ Type1.5_Front 209 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WWAA 2.953 None DFGin‑BLAminus in-none in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 4 - 253 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW5A 1.997 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Type1.5_Front 5 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAA 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 544 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAB 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 543 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4A 1.95 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4B 1.95 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 989 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCC 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 995 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCD 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEC 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 594 - 996 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXED 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEE 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEF 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2A 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2B 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0A 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ADP, QUE ATPlike, Allosteric 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0B 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP, QUE ATPlike, Allosteric 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMA 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMB 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMC 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMD 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDME 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMF 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMG 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVC 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVD 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVE 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVF 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVG 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVH 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVI 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVJ 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVK 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVL 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVM 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVN 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJA 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJB 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJC 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJD 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJE 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJF 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJG 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJH 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJI 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJJ 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJK 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJL 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJM 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJN 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1A 3.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1B 3.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7B 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7E 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 252 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7F 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7H 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 250 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7I 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 229 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7K 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 232 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7L 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KN 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KO 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 224 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER VPS15 VPS15_YEAST 5KC2B 28.0 Inactive None‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 1454 0 None None Serine/threonine-protein kinase VPS15 Saccharomyces cerevisiae
OTHER VPS15 VPS15_YEAST 5DFZB 4.4 Inactive None‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 1454 0 None None Serine/threonine-protein kinase VPS15 Saccharomyces cerevisiae
OTHER RNASEL A5H025_PIG 4O1PA 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PB 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PC 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PD 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OA 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OB 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OC 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OD 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11A 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11B 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12B 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, J60 Allosteric, Type1 24 - 726 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYA 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYB 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSA 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSB 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7ELWA 3.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, MYC Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7ELWB 3.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, MYC Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12A 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa J60, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M13A 2.56 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa BWC, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M13B 2.56 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa BWC, 25L Type1, Allosteric 23 - 729 0 None None Ribonuclease L Sus scrofa
OTHER TCUR0376 D1A2F7_THECD 8CAVA 2.87 Inactive DFGout‑None out-na in-out nonTYR APEdihe_aaiii APEdist_oiii ANP Allosteric 6 - 865 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR0376 D1A2F7_THECD 8CAVB 2.87 Inactive DFGout‑None out-na in-out nonTYR APEdihe_aaiii APEdist_oiii ANP Allosteric 6 - 863 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR0376 D1A2F7_THECD 8CARA 2.68 Inactive None‑None out-na in-out nonTYR APEdihe_aaoio APEdist_oiio No_ligand No_ligand 1 - 861 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 222 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 220 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 222 - 469 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 221 - 467 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER ROP18 ROP18_TOXGO 4JRNA 2.71 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_inni ANP Allosteric 187 - 548 0 None None Serine/threonine-protein kinase ROP18 Toxoplasma gondii
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATA 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATB 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATC 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATD 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATE 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATF 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP8A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 121 - 567 0 None None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP9A 2.8 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AN2 ATPlike 121 - 568 0 SEP205,TPO530 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 8UDCA 3.1 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaoai APEdist_iiii WCK Type1 122 - 566 0 None W131A,W142A,Y144A,I147A,Y225A,Y378A,F401A,F437A Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 8UCTA 2.93 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii 3YT Type1 122 - 566 0 None W131A,W142A,Y225A,Y378A,F401A,F437A Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PKNB A0A0U5FKB2_XANCI 9EEDA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi 12C Type1 82 - 363 0 None M164A Kinase domain protein Xanthomonas citri pv. citri
OTHER IKBKBL Q6INT1_XENLA 3RZFA 4.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo XNM Type1 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8A 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8B 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8C 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8D 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8E 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8F 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8G 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8H 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER YOPO Q93KQ6_YEREN 5CE3B 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 5CE3D 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 4CI6B 2.651 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii No_ligand No_ligand 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays

OTHER / All / All

Total number of chains: 358
Active chains: 48
Total number of genes: 48
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 146 40.8% 4Y0XA
DFGin BLBminus 53 14.8% 6CN9B
DFGin None 48 13.4% 5GZAA
DFGin ABAminus 33 9.2% 7Q52AAA
None None 32 8.9% 4IX3A
DFGout None 17 4.7% 4I93A
DFGin BLBplus 14 3.9% 5UV4A
DFGin BLAplus 6 1.7% 4JLCA
DFGin BLBtrans 3 0.8% 5DRBA
DFGinter None 3 0.8% 7MXJA
DFGout BBAminus 3 0.8% 6CPYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I92A 1.6 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93A 1.5 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93B 1.5 Pseudo DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAA 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAB 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAC 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAD 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4A 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4B 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4C 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4D 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER T1N2412 Q94K14_ARATH 8K20B 3.7 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 14 - 221 0 None None non-specific serine/threonine protein kinase Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TB 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TE 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TH 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TK 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5TN 3.4 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoio APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5UB 3.9 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaooi APEdist_iiii No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5VB 4.25 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaoii APEdist_iiii No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J6IB 3.7 Inactive DFGin‑BLAminus in-na in-out nonTYR APEdihe_aaooi APEdist_iiio No_ligand No_ligand 17 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER ZRK1 ZRK1_ARATH 6J5WB 3.7 Inactive DFGin‑BLAplus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 15 - 347 0 None None Serine/threonine-protein kinase ZRK1 Arabidopsis thaliana
OTHER YABT PKN1_BACSU 6G4JA 1.599 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 1 - 273 0 None None Serine/threonine-protein kinase YabT Bacillus subtilis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPA 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAPB 2.52 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 863 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMA 2.15 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAMB 2.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn ATP ATPlike 1 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOB 2.502 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER LANKC A0A6H0TJ16_BACTU 8SAOD 2.502 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 862 0 None None Class III lanthionine synthetase LanKC Bacillus thuringiensis serovar andalousiensis
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PKNG Q8NM29_CORGL 7MXBA 2.2 Inactive DFGin‑None out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MAP Type1 52 - 728 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXJA 1.92 Inactive DFGinter‑None out-out in-out nonTYR APEdihe_aaiii APEdist_ioii MAP Type1 62 - 358 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXKA 1.99 Inactive DFGinter‑None out-out in-out nonTYR APEdihe_aaiii APEdist_ioii MAP Type1 63 - 360 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PKNG Q8NM29_CORGL 7MXBB 2.2 Inactive DFGinter‑None out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MAP Type1 54 - 727 0 None None non-specific serine/threonine protein kinase Corynebacterium glutamicum
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus out-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
OTHER POMK SG196_DANRE 5GZAA 2.0 Pseudo DFGin‑None none-na in-out nonTYR APEdihe_aaioo APEdist_iioo ADP, ZZ1 ATPlike, Allosteric 53 - 342 0 None None Protein O-mannose kinase Danio rerio
OTHER BUBR1 A1Z6I7_DROME 6JKMA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo ADP ATPlike 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER BUBR1 A1Z6I7_DROME 6JKKA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 1127 - 1459 0 None None Bub1-related kinase Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CLRA 3.706 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 2 - 407 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CLRB 3.706 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiii No_ligand No_ligand 2 - 403 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER TKUL E9B6S8_LEIMU 9GMPA 1.89 Inactive DFGin‑BLBplus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 647 - 921 0 None None Protein kinase domain-containing protein Leishmania mexicana
OTHER NFR5-12 Q70KR1_LOTJA 8S79A 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 280 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER NFR5-12 Q70KR1_LOTJA 8S79B 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 300 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER BUD32 KAE1B_METJA 8UNKB 2.91 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 356 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 9D85B 3.59 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 2VWBA 3.05 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Allosteric 1 - 530 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 2VWBB 3.05 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Allosteric 1 - 532 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3EN9A 2.67 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR Allosteric 1 - 534 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3EN9B 2.67 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR Allosteric 1 - 529 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3ENHA 3.6 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR, TBR, TBR Allosteric, Allosteric, Allosteric 1 - 534 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 3ENHB 3.6 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBR, TBR, TBR, TBR Allosteric, Allosteric, Allosteric, Allosteric 1 - 529 0 None None Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER BUD32 KAE1B_METJA 8UP5B 3.56 Inactive DFGin‑None in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 345 - 533 0 None E478R Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Methanocaldococcus jannaschii
OTHER STT7 C1EBN1_MICCC 4IX3A 1.35 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX3B 1.35 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX4A 1.499 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX4B 1.499 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX5A 1.7 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX5B 1.7 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ANP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX6A 1.6 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER STT7 C1EBN1_MICCC 4IX6B 1.6 Inactive None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn ADP none 151 - 489 0 None None Protein kinase domain-containing protein Micromonas commoda
OTHER AAK1 AAK1_MOUSE 7LVIA 2.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFY Type1 34 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVHA 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFS Type1 34 - 328 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVHB 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 35 - 329 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7LVIB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 35 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ6A 2.132 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV Type1 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ6B 2.132 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5OI Type1 32 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ7A 2.124 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5P6 Type1 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ7B 2.124 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5P6 Type1 31 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ8A 2.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 5QI, PG6 Type1, Allosteric 33 - 329 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER AAK1 AAK1_MOUSE 7RJ8B 2.59 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii YFV, PG6 Type1, Allosteric 26 - 330 0 None None AP2-associated protein kinase 1 Mus musculus
OTHER EIF2AK3 E2AK3_MOUSE 3QD2B 2.81 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aanoo APEdist_iiin No_ligand No_ligand 582 - 1078 0 TPO980 None Eukaryotic translation initiation factor 2-alpha kinase 3 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4B 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4C 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4D 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 961 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5B 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5C 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi ADP ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5D 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaioi APEdist_nioi ADP ATPlike 561 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3A 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 560 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL3B 2.9 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31J, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL4A 3.0 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 31K, ADP Allosteric, ATPlike 562 - 963 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER ERN1 ERN1_MOUSE 4PL5A 3.4 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiii APEdist_nioi 31L, ADP, PEU Allosteric, ATPlike, Allosteric 562 - 964 0 None N772Y Serine/threonine-protein kinase/endoribonuclease IRE1 Mus musculus
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER TBK1 TBK1_MOUSE 4JL9A 3.1 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno BX7 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 4JLCA 3.0 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno SU6 Type1 2 - 656 0 None None Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CA 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aanoo APEdist_nnnn BX7 Type1 2 - 651 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER TBK1 TBK1_MOUSE 6O8CB 3.17 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoio APEdist_nnno BX7 Type1 2 - 653 0 None S172A Serine/threonine-protein kinase TBK1 Mus musculus
OTHER PKNA PKNA_MYCTU 6B2QB 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo CJJ Type1 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QC 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnno CJJ Type1 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QD 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nioo CJJ Type1 3 - 283 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 6B2QA 2.88 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno CJJ, 0BD Type1, Allosteric 3 - 284 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4OW8A 2.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 3 - 283 0 None None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FA 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 3 - 289 0 SEP46,TPO152,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FB 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 1 - 289 0 TPO21,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FC 2.9 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 289 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUA 3.0 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 3 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1MRUB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 286 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 1O6YA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6B2PA 3.01 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn CJJ Type1 4 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMA 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnno MIX Type1 3 - 277 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMB 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_nnno MIX Type1 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMD 2.89 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioo APEdist_nnoo MIX Type1 3 - 277 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 5U94A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi G93 Type1.5_Back 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3OROA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooo APEdist_oioo AGS, NHE ATPlike, Allosteric 9 - 288 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 2FUMC 2.89 Inactive DFGin‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn MIX Type1 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PA 2.37 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_iooo ACP ATPlike 1 - 278 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 6I2PB 2.37 Inactive None‑None in-out none-out nonTYR APEdihe_aanno APEdist_onnn ACP ATPlike 2 - 277 0 TPO171,TPO173 L33E Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F69A 2.8 Inactive None‑None in-out out-out nonTYR APEdihe_aanio APEdist_nnnn XDR Type1 3 - 287 0 TPO171 L33D,M145L,M155V Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F69B 2.8 Inactive None‑None in-out out-out nonTYR APEdihe_aaooo APEdist_nnoo XDR Type1 2 - 287 0 TPO171 L33D,M145L,M155V Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNE PKNE_MYCTU 2H34A 2.8 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 14 - 276 0 None None Serine/threonine-protein kinase PknE Mycobacterium tuberculosis
OTHER PKNE PKNE_MYCTU 2H34B 2.8 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 14 - 276 0 None None Serine/threonine-protein kinase PknE Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAA 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 3 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAB 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaini APEdist_nnno V17 Type1 3 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAC 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 24 - 278 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNF PKNF_MYCTU 7NAAD 2.75 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn V17 Type1 4 - 277 0 None None Serine/threonine-protein kinase PknF Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 7Q52AAA 2.35 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FE, 8ZC Allosteric, Type1 87 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIA 2.4 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii AXX Type1 74 - 746 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 2PZIB 2.4 Inactive DFGin‑ABAminus out-out in-none nonTYR APEdihe_aaiii APEdist_niii AXX Type1 74 - 745 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y0XA 1.74 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii ADP ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNG PKNG_MYCTU 4Y12A 1.9 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii AGS ATPlike 83 - 404 0 None None Serine/threonine-protein kinase PknG Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07A 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07B 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAA 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 260 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAB 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 257 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09A 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09B 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08A 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08B 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER FLS2 FLS2_ORYSJ 8JUPA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ATP ATPlike 861 - 1176 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER FLS2 FLS2_ORYSJ 8JUVA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oooo ADP ATPlike 861 - 1178 0 None None LRR receptor-like serine/threonine-protein kinase FLS2 Oryza sativa
OTHER PINK1 PINK1_PEDHC 6EQIC 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 147 - 574 0 SEP202,SEP204,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4KA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 117 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4KB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4LA 3.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 117 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4LB 3.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 SEP202 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYFA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYFB 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MA 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MB 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MC 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MD 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4ME 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MF 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MG 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MH 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MI 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MJ 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4MK 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4ML 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4NA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 116 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T4NB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 120 - 574 0 None D357A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 7T3XA 3.53 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 119 - 573 0 None D334A Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYB 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYG 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 157 - 559 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYH 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 158 - 560 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYA 2.814 Inactive None‑None none-na in-in nonTYR APEdihe_aaiai APEdist_iiii AGS, PE4 ATPlike, Allosteric 157 - 561 0 None None non-specific serine/threonine protein kinase Plasmodium falciparum
OTHER PK7 O96214_PLAFA 2PMLX 2.6 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 316 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER PK7 Q7YTF7_PLAF7 2PMNX 2.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii K51 Type1 1 - 343 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER PK7 Q7YTF7_PLAF7 2PMOX 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HMD Type1 1 - 343 0 None None mitogen-activated protein kinase kinase Plasmodium falciparum
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXB 2.771 Pseudo DFGin‑BLAminus none-na in-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 909 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXA 2.771 Pseudo None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 914 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 9D3FA 2.0 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 211 - 482 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9A 1.8 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 480 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 4Q2AA 3.5 Inactive DFGin‑BLAminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 480 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9B 1.8 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 481 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 7UOSA 2.9 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo WIB Type1 211 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TA 2.01 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5W7TB 2.01 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 210 - 482 0 SEP382 None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 5DRBA 1.65 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioo APEdist_oooo 5FJ Type1.5_Front 209 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WWAA 2.953 None DFGin‑BLAminus in-none in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 4 - 253 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW5A 1.997 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP Type1.5_Front 5 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT68 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT6H 3.2 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7PT78 3.8 Inactive DFGin‑ABAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiii ADP, BEF ATPlike, Allosteric 10 - 475 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7V3VH 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii AGS ATPlike 12 - 473 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CDC7 CDC7_YEAST 7P5Z1 3.3 Inactive DFGin‑BLAplus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 16 - 471 0 None None Cell division control protein 7 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAA 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 544 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAB 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 543 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4A 1.95 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4B 1.95 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 989 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCC 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 995 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCD 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEC 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 594 - 996 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXED 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEE 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEF 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2A 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ2B 3.33 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn IZA Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOA 2.4 None DFGin‑BLAminus out-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 2RIOB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ADP ATPlike 665 - 1115 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0A 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn ADP, QUE ATPlike, Allosteric 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ0B 3.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ADP, QUE ATPlike, Allosteric 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMA 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMB 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMC 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMD 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDME 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMF 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDMG 6.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVC 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVD 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVE 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVF 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVG 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVH 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVI 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVJ 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVK 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVL 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVM 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3FBVN 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJA 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJB 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJC 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJD 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJE 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJF 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJG 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJH 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJI 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJJ 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 672 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJK 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 663 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJL 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJM 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3SDJN 3.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo APJ Type1 670 - 1115 0 SEP840,SEP841,TPO844 H1061N Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1A 3.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER IRE1 IRE1_YEAST 3LJ1B 3.33 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanni APEdist_nnnn DKI Type1 665 - 1115 0 SEP840,SEP841,TPO844 None Serine/threonine-protein kinase/endoribonuclease IRE1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7B 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7E 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 252 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7F 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7H 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 250 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7I 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 229 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7K 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 232 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7L 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KN 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KO 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 224 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER VPS15 VPS15_YEAST 5KC2B 28.0 Inactive None‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 1454 0 None None Serine/threonine-protein kinase VPS15 Saccharomyces cerevisiae
OTHER VPS15 VPS15_YEAST 5DFZB 4.4 Inactive None‑None out-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 1454 0 None None Serine/threonine-protein kinase VPS15 Saccharomyces cerevisiae
OTHER RNASEL A5H025_PIG 4O1PA 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PB 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PC 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1PD 2.5 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP, 25L ATPlike, Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OA 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OB 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OC 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 4O1OD 3.27 Inactive DFGin‑ABAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L Allosteric 22 - 729 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11A 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M11B 2.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, B49 Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12B 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, J60 Allosteric, Type1 24 - 726 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYA 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DSYB 2.651 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, HFX Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSA 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7DTSB 2.63 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25A, 27K Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7ELWA 3.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, MYC Allosteric, Type1 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 7ELWB 3.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 25L, MYC Allosteric, Type1 23 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M12A 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa J60, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M13A 2.56 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa BWC, 25L Type1, Allosteric 22 - 727 0 None None Ribonuclease L Sus scrofa
OTHER RNASEL A5H025_PIG 6M13B 2.56 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa BWC, 25L Type1, Allosteric 23 - 729 0 None None Ribonuclease L Sus scrofa
OTHER TCUR0376 D1A2F7_THECD 8CAVA 2.87 Inactive DFGout‑None out-na in-out nonTYR APEdihe_aaiii APEdist_oiii ANP Allosteric 6 - 865 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR0376 D1A2F7_THECD 8CAVB 2.87 Inactive DFGout‑None out-na in-out nonTYR APEdihe_aaiii APEdist_oiii ANP Allosteric 6 - 863 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR0376 D1A2F7_THECD 8CARA 2.68 Inactive None‑None out-na in-out nonTYR APEdihe_aaoio APEdist_oiio No_ligand No_ligand 1 - 861 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 222 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ6B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 220 - 468 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7A 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 222 - 469 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER TCUR3610 D1ABX1_THECD 7WJ7B 2.55 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn XYA Type1 221 - 467 0 None None Serine/threonine protein kinase Thermomonospora curvata
OTHER ROP18 ROP18_TOXGO 4JRNA 2.71 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_inni ANP Allosteric 187 - 548 0 None None Serine/threonine-protein kinase ROP18 Toxoplasma gondii
OTHER PINK1 PINK1_TRICA 5YJ9D 2.53 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii ANP ATPlike 166 - 570 0 None S205D,S377D,T386E,T530E Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATA 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATB 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATC 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATD 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATE 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 5OATF 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiao APEdist_iiii No_ligand No_ligand 156 - 566 0 SEP207 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP8A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 121 - 567 0 None None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 7MP9A 2.8 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AN2 ATPlike 121 - 568 0 SEP205,TPO530 None Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 8UDCA 3.1 Inactive DFGin‑None in-out in-out nonTYR APEdihe_aaoai APEdist_iiii WCK Type1 122 - 566 0 None W131A,W142A,Y144A,I147A,Y225A,Y378A,F401A,F437A Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PINK1 PINK1_TRICA 8UCTA 2.93 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiai APEdist_iiii 3YT Type1 122 - 566 0 None W131A,W142A,Y225A,Y378A,F401A,F437A Serine/threonine-protein kinase Pink1, mitochondrial Tribolium castaneum
OTHER PKNB A0A0U5FKB2_XANCI 9EEDA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi 12C Type1 82 - 363 0 None M164A Kinase domain protein Xanthomonas citri pv. citri
OTHER IKBKBL Q6INT1_XENLA 3RZFA 4.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioo APEdist_iioo XNM Type1 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8A 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8B 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8C 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8D 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8E 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8F 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 650 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8G 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER IKBKBL Q6INT1_XENLA 3QA8H 3.6 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 1 - 621 0 None S161E,S165E IkappaB kinase Xenopus laevis
OTHER YOPO Q93KQ6_YEREN 5CE3B 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 5CE3D 2.93 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii ADP ATPlike 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER YOPO Q93KQ6_YEREN 4CI6B 2.651 Inactive None‑None none-na in-out nonTYR APEdihe_aaiii APEdist_ooii No_ligand No_ligand 108 - 729 0 None K205Y,E206Y,E207Y,K440Y,K441Y YopO Yersinia enterocolitica
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays