8R9B

CDK7 (Cyclin-dependent kinase 7)
Group: CMGC
Uniprot: CDK7_HUMAN
Organism: Homo sapiens
Domain boundary: 12 - 296
Resolu: 2.21

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out out-out ANP Type1 1 - 311 0
B Inactive DFGin None out-out out-out ANP Type1 3 - 310 0
C Inactive DFGin None out-out out-out ANP Type1 8 - 311 12
D Inactive DFGin None out-out out-out ANP Type1 9 - 311 10
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         -          -          4         14 
imsyyhhhhh hdydiptten lyfqgsmald vksrAKRYEK 
        24         34         44         54 
LDFLGEGQFA TVYKARDKNT NQIVAIKKIk lghrseakdg 
        64         74         84         94 
inrTALREIK LLQELSHPNI IGLLDAFGhk SNISLVFDFM 
       104        114        124        134 
ETDLEVIIKD NSLVLTPSHI KAYMLMTLQG LEYLHQHWIL 
       144        154        164        174 
HRDLKPNNLL LDENGVLKLA DFGLAKSFgd pnrayehqVV 
       184        194        204        214 
TRWYRAPELL FGARMYGVGV DMWAVGCILA ELLLRVPFLP 
       224        234        244        254 
GDSDLDQLTR IFETLGTPTE EQWPDMCSLP DYVTFKSFPG 
       264        274        284        294 
IPLHHIFSAA GDDLLDLIQG LFLFNPCARI TATQALKMKY 
       304        314        324 
FSNRPGPTPG CQLPRPNcpv etlkeqsnpa la
Lower-case residues are disordered in structure.
Mutations: S164D,T170E
Phosphorylation: None