TYR_PTK2B (Protein-tyrosine kinase 2-beta)

Total number of chains: 16
Active chains: 2
Uniprot: FAK2_HUMAN
Kinase Domain Residues: 425 - 681
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 6 37.5% 4H1JA
DFGin None 5 31.2% 3CC6A
DFGin BLAminus 2 12.5% AF-Q14289-K1A
DFGout BBAminus 2 12.5% 4H1MA
None None 1 6.2% 3H3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q14289-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta
AF-Q14289-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta
3FZOA 2.2 Inactive DFGin‑None in-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta
8YGXA 2.0 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta
3CC6A 1.6 Inactive DFGin‑None in-in out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 415 - 692 0 None None Protein-tyrosine kinase 2-beta
8XOXA 1.9 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao YAM Type1 417 - 692 0 None None Protein-tyrosine kinase 2-beta
5TOBA 2.117 Inactive DFGin‑None in-none none-none TYR APEdihe_nnnai APEdist_aaan YAM Type1 420 - 690 0 None None Protein-tyrosine kinase 2-beta
3FZSA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai B96 Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
4H1MA 1.99 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 0YJ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
3FZPA 2.1 Inactive DFGout‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 419 - 692 0 None None Protein-tyrosine kinase 2-beta
3ET7A 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 349 Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta
3FZRA 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 3JZ Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta
5TO8A 1.985 Inactive DFGout‑None in-none out-none TYR APEdihe_nnnan APEdist_aaan 7FM Type1 420 - 691 0 None None Protein-tyrosine kinase 2-beta
3FZTA 1.95 Inactive DFGout‑None in-in out-none TYR APEdihe_nniai APEdist_aaai 4JZ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
4H1JA 2.0 Inactive DFGout‑None in-in out-out TYR APEdihe_oiiai APEdist_aaai 0YH Type2 419 - 690 0 None None Protein-tyrosine kinase 2-beta
3H3CA 2.0 Inactive None‑None in-out none-out TYR APEdihe_oiiai APEdist_aaai P1E Type1 416 - 692 0 None None Protein-tyrosine kinase 2-beta

TYR_PTK2B (Protein-tyrosine kinase 2-beta)

Total number of chains: 16
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 6 37.5% 4H1JA
DFGin None 5 31.2% 3CC6A
DFGin BLAminus 2 12.5% AF-Q14289-K1A
DFGout BBAminus 2 12.5% 4H1MA
None None 1 6.2% 3H3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FAK2_HUMAN AF-Q14289-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN AF-Q14289-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3FZOA 2.2 Inactive DFGin‑None in-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 8YGXA 2.0 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3CC6A 1.6 Inactive DFGin‑None in-in out-out TYR APEdihe_oiiai APEdist_aaao No_ligand No_ligand 415 - 692 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 8XOXA 1.9 Inactive DFGin‑None in-out none-out TYR APEdihe_nniai APEdist_aaao YAM Type1 417 - 692 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 5TOBA 2.117 Inactive DFGin‑None in-none none-none TYR APEdihe_nnnai APEdist_aaan YAM Type1 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3FZSA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai B96 Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 4H1MA 1.99 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 0YJ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3FZPA 2.1 Inactive DFGout‑None in-out none-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 419 - 692 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3ET7A 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 349 Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3FZRA 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 3JZ Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 5TO8A 1.985 Inactive DFGout‑None in-none out-none TYR APEdihe_nnnan APEdist_aaan 7FM Type1 420 - 691 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3FZTA 1.95 Inactive DFGout‑None in-in out-none TYR APEdihe_nniai APEdist_aaai 4JZ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 4H1JA 2.0 Inactive DFGout‑None in-in out-out TYR APEdihe_oiiai APEdist_aaai 0YH Type2 419 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
FAK2_HUMAN 3H3CA 2.0 Inactive None‑None in-out none-out TYR APEdihe_oiiai APEdist_aaai P1E Type1 416 - 692 0 None None Protein-tyrosine kinase 2-beta Homo sapiens

TYR_PTK2B (Protein-tyrosine kinase 2-beta)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism