TKL_LIMK1 (LIM domain kinase 1)

Total number of chains: 20
Active chains: 7
Uniprot: LIMK1_HUMAN
Kinase Domain Residues: 339 - 606
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 45.0% AF-P53667-K1A
DFGout BBAminus 8 40.0% 7ATUB
DFGin None 2 10.0% 5HVKC
DFGin BLBplus 1 5.0% 7ATSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1
5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1
AF-P53667-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1
AF-P53667-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1
3S95A 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1
3S95B 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1
8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1
5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1
7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1
5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1
5NXCL 2.25 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiai APEdist_nnno 9DB Type1 330 - 632 0 None None LIM domain kinase 1
7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1
7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1
7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1
7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1
7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1
7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1
5HVJB 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiai APEdist_niii No_ligand No_ligand 330 - 637 0 None D460N LIM domain kinase 1

TKL_LIMK1 (LIM domain kinase 1)

Total number of chains: 20
Active chains: 7
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 45.0% AF-P53667-K1A
DFGout BBAminus 8 40.0% 7ATUB
DFGin None 2 10.0% 5HVKC
DFGin BLBplus 1 5.0% 7ATSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN AF-P53667-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN AF-P53667-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 331 - 614 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 3S95A 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 3S95B 1.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii STU Type1 330 - 637 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 8AAUL 1.74 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii LH0 Type1 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 5HVJA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_oiio ANP ATPlike 329 - 633 0 None D460N LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 5HVKC 3.5 Inactive DFGin‑None in-out in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 633 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 5NXCL 2.25 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiai APEdist_nnno 9DB Type1 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1 Homo sapiens
LIMK1_HUMAN 5HVJB 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiai APEdist_niii No_ligand No_ligand 330 - 637 0 None D460N LIM domain kinase 1 Homo sapiens

TKL_LIMK1 (LIM domain kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism