CMGC_CDK1 (Cyclin-dependent kinase 1)

Total number of chains: 21
Active chains: 2
Uniprot: CDK1_HUMAN
Kinase Domain Residues: 4 - 287
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 57.1% AF-P06493-K1A
DFGin BLBplus 9 42.9% 6GU7C
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P06493-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 295 0 None None Cyclin-dependent kinase 1
AF-P06493-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 295 0 None None Cyclin-dependent kinase 1
9SKQA 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiii ANP ATPlike 3 - 288 0 TPO161 None Cyclin-dependent kinase 1
4YC3A 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 1 - 297 0 None None Cyclin-dependent kinase 1
7NJ0B 3.6 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 290 0 TPO161 None Cyclin-dependent kinase 1
4Y72A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo LZ9 Type1 1 - 289 0 None None Cyclin-dependent kinase 1
5HQ0A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo LZ9 Type1 1 - 289 0 None None Cyclin-dependent kinase 1
5LQFA 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 4SP Type1 1 - 289 0 None None Cyclin-dependent kinase 1
5LQFD 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 4SP Type1 1 - 289 0 None None Cyclin-dependent kinase 1
6GU2A 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno F9Z Type1 1 - 294 0 None None Cyclin-dependent kinase 1
6GU3A 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo FB8 Type1 1 - 289 0 None None Cyclin-dependent kinase 1
6GU4A 2.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio FC8 Type1 1 - 289 0 None None Cyclin-dependent kinase 1
4YC6A 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
4YC6C 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
4YC6E 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
4YC6G 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1
6GU7C 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1
6GU7E 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 1
6GU7G 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1
6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1
6GU7A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno FB8 Type1 1 - 293 0 None None Cyclin-dependent kinase 1

CMGC_CDK1 (Cyclin-dependent kinase 1)

Total number of chains: 21
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 57.1% AF-P06493-K1A
DFGin BLBplus 9 42.9% 6GU7C
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDK1_HUMAN AF-P06493-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 295 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN AF-P06493-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 295 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 9SKQA 3.4 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiii ANP ATPlike 3 - 288 0 TPO161 None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4YC3A 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 1 - 297 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 7NJ0B 3.6 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 290 0 TPO161 None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4Y72A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo LZ9 Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 5HQ0A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo LZ9 Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 5LQFA 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 4SP Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 5LQFD 2.06 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 4SP Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU2A 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno F9Z Type1 1 - 294 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU3A 2.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo FB8 Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU4A 2.73 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiio FC8 Type1 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4YC6A 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4YC6C 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4YC6E 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 4YC6G 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 289 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU7C 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU7E 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 292 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU7G 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU6A 2.33 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 1QK Type1 1 - 291 0 None None Cyclin-dependent kinase 1 Homo sapiens
CDK1_HUMAN 6GU7A 2.75 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno FB8 Type1 1 - 293 0 None None Cyclin-dependent kinase 1 Homo sapiens

CMGC_CDK1 (Cyclin-dependent kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism