CMGC_CDK9 (Cyclin-dependent kinase 9)

Total number of chains: 35
Active chains: 25
Family: CMGC
Uniprot: CDK9_HUMAN
Kinase Domain Residues: 19 - 315
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 35 100.0% AF-P50750-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9
4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9
AF-P50750-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 323 0 None None Cyclin-dependent kinase 9
AF-P50750-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 323 0 None None Cyclin-dependent kinase 9
4OR5A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 331 0 TPO186 None Cyclin-dependent kinase 9
4OR5F 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 332 0 TPO186 None Cyclin-dependent kinase 9
5L1ZA 5.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
6CYTA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
3MI9A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 344 0 TPO186 None Cyclin-dependent kinase 9
4EC8A 3.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 338 0 TPO186 None Cyclin-dependent kinase 9
4EC9A 3.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 327 0 TPO186 None Cyclin-dependent kinase 9
4BCFA 3.011 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii T6Q Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9
8I0LA 3.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NJ6 Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9
6GZHA 3.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 8 - 326 0 TPO186 None Cyclin-dependent kinase 9
3LQ5A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SLQ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9
3MY1A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9
3TN8A 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F18 Type1 8 - 325 0 TPO186 None Cyclin-dependent kinase 9
3TNHA 3.202 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F18 Type1 8 - 328 0 TPO186 None Cyclin-dependent kinase 9
4OGRA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
4OGRE 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
4OGRI 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
6W9EA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TO7, TO7, TOJ, TOJ Type1, Type1, Type1, Type1 7 - 326 0 TPO186,SEP306 None Cyclin-dependent kinase 9
4IMYA 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP Type1.5_Back 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
3BLHA 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 325 0 TPO186 None Cyclin-dependent kinase 9
3TNIA 3.234 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 325 0 TPO186 None Cyclin-dependent kinase 9
7NWKA 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii UT5 Type1 7 - 326 0 TPO186 None Cyclin-dependent kinase 9
3BLRA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii CPB Type1 7 - 326 0 TPO186 None Cyclin-dependent kinase 9
4BCGA 3.085 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T3C Type1 7 - 327 0 TPO186 None Cyclin-dependent kinase 9
4BCHA 2.958 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T7Z Type1 7 - 327 0 TPO186 None Cyclin-dependent kinase 9
4BCIA 3.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T3E Type1 5 - 326 0 TPO186 None Cyclin-dependent kinase 9
4BCJA 3.162 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T9N Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9
8K5RA 3.751 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VQE Type1 5 - 327 0 TPO186 S7D,V8N,K44R,Y138F,K280A,D307E,N311E Cyclin-dependent kinase 9
6Z45A 3.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii Q6E Type1 5 - 328 0 TPO186 None Cyclin-dependent kinase 9

CMGC_CDK9 (Cyclin-dependent kinase 9)

Total number of chains: 35
Active chains: 25
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 35 100.0% AF-P50750-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CDK9_HUMAN 3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN AF-P50750-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 323 0 None None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN AF-P50750-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 323 0 None None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4OR5A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 331 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4OR5F 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 332 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 5L1ZA 5.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 6CYTA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3MI9A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 344 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4EC8A 3.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 338 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4EC9A 3.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4BCFA 3.011 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii T6Q Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 8I0LA 3.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NJ6 Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 6GZHA 3.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LCI Type1 8 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3LQ5A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SLQ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3MY1A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3TN8A 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F18 Type1 8 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3TNHA 3.202 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii F18 Type1 8 - 328 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4OGRA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4OGRE 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4OGRI 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADN Type1 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 6W9EA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TO7, TO7, TOJ, TOJ Type1, Type1, Type1, Type1 7 - 326 0 TPO186,SEP306 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4IMYA 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP Type1.5_Back 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3BLHA 2.48 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3TNIA 3.234 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 7NWKA 2.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii UT5 Type1 7 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 3BLRA 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii CPB Type1 7 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4BCGA 3.085 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T3C Type1 7 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4BCHA 2.958 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T7Z Type1 7 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4BCIA 3.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T3E Type1 5 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 4BCJA 3.162 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii T9N Type1 6 - 326 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 8K5RA 3.751 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii VQE Type1 5 - 327 0 TPO186 S7D,V8N,K44R,Y138F,K280A,D307E,N311E Cyclin-dependent kinase 9 Homo sapiens
CDK9_HUMAN 6Z45A 3.37 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii Q6E Type1 5 - 328 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens

CMGC_CDK9 (Cyclin-dependent kinase 9)

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism