| Chain id | Group | Gene | UniprotID | Protein | Organism | Activity | Spatial | Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B | STE | MAP2K1 | MP2K1_HUMAN | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | AGS LCJ | Type1 Type3 | 62 - 380 | 0 |
| A | TKL | RAF1 | RAF1_HUMAN | RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | AGS | Type1 | 343 - 625 | 0 |
Representative sequence - Chain A
- - 8 18
mgsshhhhhh savdenlyfq ggmehiqgaw ktisngfgfk
28 38 48 58
davfdgssci sptivqqfgy qrrasddgkl tdpsktsnti
68 78 88 98
rvflpnkqrt vvnvrngmsl hdclmkalkv rglqpeccav
108 118 128 138
frllhehkgk karldwntda asligeelqv dfldhvpltt
148 158 168 178
hnfarktflk lafcdicrkf llngfrcqtc gykfhehcst
188 198 208 218
kvptmcvdws nirqlllfpn stigdsgvpa lpsltmrrmr
228 238 248 258
esvsrmpvss qhrystphaf tfntsspsse gslsqrqrst
268 278 288 298
stpnvhmvst tlpvdsrmie dairshsesa spsalssspn
308 318 328 338
nlsptgwsqp ktpvpaqrer apvsgtqekn kirprgqrds
348 358 368 378
sddwEIEASE VMLSTRIGSG SFGTVYKGKW HGDVAVKILK
388 398 408 418
VVDPTPEQFQ AFRNEVAVLR KTRHVNILLF MGYMTKDNLA
428 438 448 458
IVTQWCEGSS LYKHLHVQET KFQMFQLIDI ARQTAQGMDY
468 478 488 498
LHAKNIIHRD MKSNNIFLHE GLTVKIGDFG LATVKSRWSG
508 518 528 538
SQQVEQPTGS VLWMAPEVIR MQDNNPFSFQ SDVYSYGIVL
548 558 568 578
YELMTGELPY SHINNRDQII FMVGRGYASP DLSKLYKNCP
588 598 608 618
KAMKRLVAEC VKKVKEERPL FPQILSSIEL LQHSLPKINR
628 638 648 -
SASEPSLhra ahtedinact lttsprlpvf vpawshpqfe
k