| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| STE | MAP2K1 | MP2K1_HUMAN | 9MMRB | 3.9 | Inactive | DFGin‑BLBplus | out-out | out-out | nonTYR | APEdihe_aaoio | APEdist_oooo | AGS, LCJ | ATPlike, Type3 | 62 - 380 | 0 | None | S218A,S222A | Dual specificity mitogen-activated protein kinase kinase 1 |
| TKL | RAF1 | RAF1_HUMAN | 9MMRA | 3.9 | Inactive | DFGin‑BLBplus | out-out | out-out | nonTYR | APEdihe_aaiii | APEdist_oooo | AGS | ATPlike | 343 - 625 | 0 | SEP621 | Q156R,Y340D,Y341D,D587E | RAF proto-oncogene serine/threonine-protein kinase |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| STE | MAP2K1 | MP2K1_HUMAN | 9MMRB | 3.9 | Inactive | DFGin‑BLBplus | out-out | out-out | nonTYR | APEdihe_aaoio | APEdist_oooo | AGS, LCJ | ATPlike, Type3 | 62 - 380 | 0 | None | S218A,S222A | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens |
| TKL | RAF1 | RAF1_HUMAN | 9MMRA | 3.9 | Inactive | DFGin‑BLBplus | out-out | out-out | nonTYR | APEdihe_aaiii | APEdist_oooo | AGS | ATPlike | 343 - 625 | 0 | SEP621 | Q156R,Y340D,Y341D,D587E | RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|