CDK12 (Cyclin-dependent kinase 12)

Group: CMGC
Uniprot: CDK12_HUMAN
Domain boundary: 727 - 1020


Total number of chains: 108
Spatial Dihedral Chains Representative
DFGin BLAminus 52 AF-Q9NYV4-K1A
DFGin ABAminus 26 8BUNB
DFGin None 30 8BU1B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8BU2H 3.13 Inactive DFGin ABAminus in-in in-in RVQ Type1 715 - 1043 K965R X893 0
8BU4B 3.09 Inactive DFGin ABAminus in-in in-in RQL Type1 715 - 1043 K965R X893 0
8BU4H 3.09 Inactive DFGin ABAminus in-out in-in RQL Type1 715 - 1044 K965R X893 0
8BU5B 3.134 Inactive DFGin ABAminus in-out in-in RMF Type1 713 - 1044 K965R X893 0
8BU5H 3.134 Inactive DFGin ABAminus in-in in-in RMF Type1 713 - 1043 K965R X893 0
8BU9H 3.51 Inactive DFGin ABAminus in-in in-in RRC Type1 715 - 1038 K965R X893 0
8BUAB 3.193 Inactive DFGin ABAminus in-in in-in RVH Type1 715 - 1039 K965R X893 0
8BUAE 3.193 Inactive DFGin ABAminus in-out in-in RVH Type1 715 - 1033 K965R X893 0
8BUAH 3.193 Inactive DFGin ABAminus in-in in-in RVH Type1 715 - 1034 K965R X893 0
8BUCB 3.85 Inactive DFGin ABAminus in-in in-in RKO Type1 715 - 1041 K965R X893 0
8BUDB 3.2 Inactive DFGin ABAminus in-in in-in RP9 Type1 715 - 1043 K965R X893 0
8BUDH 3.2 Inactive DFGin ABAminus in-in in-in RP9 Type1 715 - 1043 K965R X893 0
8BUEH 3.25 Inactive DFGin ABAminus in-in in-in RVU Type1 715 - 1043 K965R X893 0
8BUIB 3.5 Inactive DFGin ABAminus in-in in-in RV6 Type1 715 - 1041 K965R X893 0
8BUIH 3.5 Inactive DFGin ABAminus in-in in-in RV6 Type1 715 - 1038 K965R X893 0
8BULH 3.4 Inactive DFGin ABAminus in-in in-in RSU Type1 715 - 1034 None X893 0
8BUNB 3.08 Inactive DFGin ABAminus in-in in-in RNF Type1 715 - 1041 K965R X893 0
8BUNH 3.08 Inactive DFGin ABAminus in-in in-in RNF Type1 715 - 1043 K965R X893 0
8BUOB 3.58 Inactive DFGin ABAminus in-in in-in RLC Type1 715 - 1040 K965R X893 0
8BURE 3.64 Inactive DFGin ABAminus in-in in-in RQU Type1 715 - 1040 K965R X893 0
8BUSH 3.26 Inactive DFGin ABAminus in-in in-in RMX Type1 715 - 1044 K965R X893 0
8BUTB 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1 715 - 1039 K965R X893 0
8BUTH 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1 715 - 1043 K965R X893 0
7NXKA 3.0 Inactive DFGin ABAminus in-none in-in UUB Type1 715 - 1040 None X893 0
9FMRE 3.9 Inactive DFGin ABAminus in-out in-in RMF Type1 714 - 1042 None X893 0
9FMRH 3.9 Inactive DFGin ABAminus in-in in-in RMF Type1 714 - 1044 None X893 0
AF-Q9NYV4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 719 - 1028 None None 0
4UN0C 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 719 - 1036 None X893 0
4UN0D 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 723 - 1024 None X893 5
4CXAC 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 718 - 1048 None X893 0
8BU2E 3.13 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1039 K965R X893 0
8BU7B 3.245 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
8BU7H 3.245 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
8BUDE 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
8BUGE 3.53 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1039 K965R X893 0
6B3EA 3.06 Active DFGin BLAminus in-in in-in CJM Type1 717 - 1036 None X893 0
6B3EC 3.06 Active DFGin BLAminus in-in in-in CJM Type1 719 - 1036 None X893 0
4CXAA 3.15 Active DFGin BLAminus in-in in-in ANP Type1 718 - 1050 None X893 1
5ACBC 2.7 Active DFGin BLAminus in-in in-in 5I1 Type1 716 - 1040 None X893 0
5ACBD 2.7 Active DFGin BLAminus in-in in-in 5I1 Type1 718 - 1044 None X893 3
9JK1A 2.72 Active DFGin BLAminus in-in in-in A1EB3 Type1 717 - 1039 None X893 2
9JK1B 2.72 Active DFGin BLAminus in-in in-in A1EB3 Type1 715 - 1039 None X893 0
6TD3B 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
6TD3E 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
6TD3H 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
8BU1E 2.98 Active DFGin BLAminus in-in in-in RQL Type1 715 - 1044 K965R X893 0
8BU3E 3.42 Active DFGin BLAminus in-in in-in RSI Type1 715 - 1039 K965R X893 0
8BU4E 3.09 Inactive DFGin BLAminus in-out in-in RQL Type1 715 - 1039 K965R X893 0
8BU6E 3.45 Inactive DFGin BLAminus in-out in-in RQE Type1 715 - 1038 K965R X893 0
8BU7E 3.245 Active DFGin BLAminus in-in in-in RS5 Type1 715 - 1043 K965R X893 0
8BU9E 3.51 Active DFGin BLAminus in-in in-in RRC Type1 715 - 1039 K965R X893 0
8BUBB 3.42 Inactive DFGin BLAminus in-in out-out RNU Type1 715 - 1041 K965R X893 0
8BUBE 3.42 Inactive DFGin BLAminus in-in out-out RNU Type1 715 - 1043 K965R X893 0
8BUCE 3.85 Active DFGin BLAminus in-in in-in RKO Type1 715 - 1039 K965R X893 0
8BUEE 3.25 Active DFGin BLAminus in-in in-in RVU Type1 715 - 1039 K965R X893 0
8BUFE 3.3 Active DFGin BLAminus in-in in-in RW6 Type1 715 - 1043 K965R X893 0
8BUHE 3.79 Active DFGin BLAminus in-in in-in RR9 Type1 715 - 1034 K965R X893 0
8BUIE 3.5 Inactive DFGin BLAminus in-out in-out RV6 Type1 715 - 1039 K965R X893 0
8BUJE 3.62 Inactive DFGin BLAminus in-out in-in RUW Type1 715 - 1043 K965R X893 0
8BUKE 3.41 Active DFGin BLAminus in-in in-in RWE Type1 715 - 1039 K965R X893 0
8BULE 3.4 Active DFGin BLAminus in-in in-in RSU Type1 715 - 1038 None X893 0
8BUME 3.36 Active DFGin BLAminus in-in in-in T6X Type1 715 - 1039 K965R X893 0
8BUNE 3.08 Active DFGin BLAminus in-in in-in RNF Type1 715 - 1039 K965R X893 0
8BUOE 3.58 Active DFGin BLAminus in-in in-in RLC Type1 715 - 1040 K965R X893 0
8BUPB 3.41 Active DFGin BLAminus in-in in-in RWN Type1 715 - 1027 K965R X893 0
8BUPE 3.41 Inactive DFGin BLAminus in-in in-out RWN Type1 715 - 1027 K965R X893 0
8BUPH 3.41 Active DFGin BLAminus in-in in-in RWN Type1 715 - 1028 K965R X893 0
8BUQB 3.2 Active DFGin BLAminus in-in in-in RQ9 Type1 715 - 1039 K965R X893 0
8BUQE 3.2 Active DFGin BLAminus in-in in-in RQ9 Type1 715 - 1027 K965R X893 0
8BURB 3.64 Active DFGin BLAminus in-in in-in RQU Type1 715 - 1044 K965R X893 0
8BUSB 3.26 Active DFGin BLAminus in-in in-in RMX Type1 715 - 1039 K965R X893 0
8BUTE 3.25 Active DFGin BLAminus in-in in-in RQ5 Type1 715 - 1039 K965R X893 0
4NSTA 2.2 Active DFGin BLAminus in-in in-in ADP Type1 716 - 1046 None X893 0
4NSTC 2.2 Active DFGin BLAminus in-in in-in ADP Type1 717 - 1045 None X893 1
6CKXA 2.8 Active DFGin BLAminus in-in in-in 8M1 Type1 722 - 1024 None X893 0
6CKXC 2.8 Active DFGin BLAminus in-in in-in 8M1 Type1 722 - 1024 None X893 0
7NXKC 3.0 None DFGin BLAminus in-none in-in UUB Type1 717 - 1040 None X893 0
8P81A 2.68 Active DFGin BLAminus in-in in-in RMF Type1 716 - 1035 None X893 0
8BUGH 3.53 Inactive DFGin None in-out in-in No_ligand No_ligand 715 - 1039 K965R X893 0
8BU1B 2.98 Inactive DFGin None in-in in-in RQL Type1 715 - 1044 K965R X893 0
8BU1H 2.98 Inactive DFGin None in-in in-in RQL Type1 715 - 1044 K965R X893 0
8BU2B 3.13 Inactive DFGin None in-in in-in RVQ Type1 715 - 1041 K965R X893 0
8BU3B 3.42 Inactive DFGin None in-in in-in RSI Type1 715 - 1040 K965R X893 0
8BU3H 3.42 Inactive DFGin None in-in in-in RSI Type1 715 - 1044 K965R X893 0
8BU5E 3.134 Inactive DFGin None in-out in-in RMF Type1 713 - 1043 K965R X893 0
8BU6B 3.45 Inactive DFGin None in-in in-in RQE Type1 715 - 1039 K965R X893 0
8BU6H 3.45 Inactive DFGin None in-out in-in RQE Type1 715 - 1038 K965R X893 0
8BU9B 3.51 Inactive DFGin None in-in in-in RRC Type1 715 - 1039 K965R X893 0
8BUBH 3.42 Inactive DFGin None in-in out-in RNU Type1 715 - 1044 K965R X893 0
8BUCH 3.85 Inactive DFGin None in-in in-in RKO Type1 715 - 1044 K965R X893 0
8BUEB 3.25 Inactive DFGin None in-in in-in RVU Type1 715 - 1043 K965R X893 0
8BUFB 3.3 Inactive DFGin None in-in in-in RW6 Type1 715 - 1033 K965R X893 0
8BUFH 3.3 Inactive DFGin None in-out in-in RW6 Type1 715 - 1032 K965R X893 0
8BUGB 3.53 Inactive DFGin None in-in in-in RPW Type1 715 - 1041 K965R X893 0
8BUHB 3.79 Inactive DFGin None in-in in-in RR9 Type1 715 - 1039 K965R X893 0
8BUHH 3.79 Inactive DFGin None in-in in-in RR9 Type1 715 - 1033 K965R X893 0
8BUJB 3.62 Inactive DFGin None in-in in-in RUW Type1 715 - 1041 K965R X893 0
8BUJH 3.62 Inactive DFGin None in-in in-in RUW Type1 715 - 1043 K965R X893 0
8BUKB 3.41 Inactive DFGin None in-in in-in RWE Type1 715 - 1040 K965R X893 0
8BUKH 3.41 Inactive DFGin None in-in in-in RWE Type1 715 - 1044 K965R X893 0
8BULB 3.4 Inactive DFGin None in-in in-in RSU Type1 715 - 1039 None X893 0
8BUMB 3.36 Inactive DFGin None in-in in-in T6X Type1 715 - 1040 K965R X893 0
8BUMH 3.36 Inactive DFGin None in-out in-in T6X Type1 715 - 1039 K965R X893 0
8BUOH 3.58 Inactive DFGin None in-in in-in RLC Type1 715 - 1044 K965R X893 0
8BUQH 3.2 Inactive DFGin None in-in in-in RQ9 Type1 715 - 1035 K965R X893 0
8BURH 3.64 Inactive DFGin None in-in in-in RQU Type1 715 - 1039 K965R X893 0
8BUSE 3.26 Inactive DFGin None in-in in-in RMX Type1 715 - 1043 K965R X893 0
9FMRB 3.9 Inactive DFGin None in-out in-in RMF Type1 714 - 1047 None X893 0

CDK12 (Cyclin-dependent kinase 12)

Group: CMGC
Total number of chains: 108
Spatial Dihedral Chains Representative
DFGin BLAminus 52 AF-Q9NYV4-K1A
DFGin ABAminus 26 8BUNB
DFGin None 30 8BU1B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens CDK12_HUMAN 8BU2H 3.13 Inactive DFGin ABAminus in-in in-in RVQ Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU4B 3.09 Inactive DFGin ABAminus in-in in-in RQL Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU4H 3.09 Inactive DFGin ABAminus in-out in-in RQL Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU5B 3.134 Inactive DFGin ABAminus in-out in-in RMF Type1 713 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU5H 3.134 Inactive DFGin ABAminus in-in in-in RMF Type1 713 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU9H 3.51 Inactive DFGin ABAminus in-in in-in RRC Type1 715 - 1038 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUAB 3.193 Inactive DFGin ABAminus in-in in-in RVH Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUAE 3.193 Inactive DFGin ABAminus in-out in-in RVH Type1 715 - 1033 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUAH 3.193 Inactive DFGin ABAminus in-in in-in RVH Type1 715 - 1034 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUCB 3.85 Inactive DFGin ABAminus in-in in-in RKO Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUDB 3.2 Inactive DFGin ABAminus in-in in-in RP9 Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUDH 3.2 Inactive DFGin ABAminus in-in in-in RP9 Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUEH 3.25 Inactive DFGin ABAminus in-in in-in RVU Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUIB 3.5 Inactive DFGin ABAminus in-in in-in RV6 Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUIH 3.5 Inactive DFGin ABAminus in-in in-in RV6 Type1 715 - 1038 K965R X893 0
Homo sapiens CDK12_HUMAN 8BULH 3.4 Inactive DFGin ABAminus in-in in-in RSU Type1 715 - 1034 None X893 0
Homo sapiens CDK12_HUMAN 8BUNB 3.08 Inactive DFGin ABAminus in-in in-in RNF Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUNH 3.08 Inactive DFGin ABAminus in-in in-in RNF Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUOB 3.58 Inactive DFGin ABAminus in-in in-in RLC Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BURE 3.64 Inactive DFGin ABAminus in-in in-in RQU Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUSH 3.26 Inactive DFGin ABAminus in-in in-in RMX Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUTB 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUTH 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 7NXKA 3.0 Inactive DFGin ABAminus in-none in-in UUB Type1 715 - 1040 None X893 0
Homo sapiens CDK12_HUMAN 9FMRE 3.9 Inactive DFGin ABAminus in-out in-in RMF Type1 714 - 1042 None X893 0
Homo sapiens CDK12_HUMAN 9FMRH 3.9 Inactive DFGin ABAminus in-in in-in RMF Type1 714 - 1044 None X893 0
Homo sapiens CDK12_HUMAN AF-Q9NYV4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 719 - 1028 None None 0
Homo sapiens CDK12_HUMAN 4UN0C 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 719 - 1036 None X893 0
Homo sapiens CDK12_HUMAN 4UN0D 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 723 - 1024 None X893 5
Homo sapiens CDK12_HUMAN 4CXAC 3.15 None DFGin BLAminus in-none in-in No_ligand No_ligand 718 - 1048 None X893 0
Homo sapiens CDK12_HUMAN 8BU2E 3.13 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU7B 3.245 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU7H 3.245 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUDE 3.2 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUGE 3.53 Active DFGin BLAminus in-in in-in No_ligand No_ligand 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 6B3EA 3.06 Active DFGin BLAminus in-in in-in CJM Type1 717 - 1036 None X893 0
Homo sapiens CDK12_HUMAN 6B3EC 3.06 Active DFGin BLAminus in-in in-in CJM Type1 719 - 1036 None X893 0
Homo sapiens CDK12_HUMAN 4CXAA 3.15 Active DFGin BLAminus in-in in-in ANP Type1 718 - 1050 None X893 1
Homo sapiens CDK12_HUMAN 5ACBC 2.7 Active DFGin BLAminus in-in in-in 5I1 Type1 716 - 1040 None X893 0
Homo sapiens CDK12_HUMAN 5ACBD 2.7 Active DFGin BLAminus in-in in-in 5I1 Type1 718 - 1044 None X893 3
Homo sapiens CDK12_HUMAN 9JK1A 2.72 Active DFGin BLAminus in-in in-in A1EB3 Type1 717 - 1039 None X893 2
Homo sapiens CDK12_HUMAN 9JK1B 2.72 Active DFGin BLAminus in-in in-in A1EB3 Type1 715 - 1039 None X893 0
Homo sapiens CDK12_HUMAN 6TD3B 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
Homo sapiens CDK12_HUMAN 6TD3E 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
Homo sapiens CDK12_HUMAN 6TD3H 3.46 Active DFGin BLAminus in-in in-in RC8 Type1 715 - 1047 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU1E 2.98 Active DFGin BLAminus in-in in-in RQL Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU3E 3.42 Active DFGin BLAminus in-in in-in RSI Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU4E 3.09 Inactive DFGin BLAminus in-out in-in RQL Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU6E 3.45 Inactive DFGin BLAminus in-out in-in RQE Type1 715 - 1038 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU7E 3.245 Active DFGin BLAminus in-in in-in RS5 Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU9E 3.51 Active DFGin BLAminus in-in in-in RRC Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUBB 3.42 Inactive DFGin BLAminus in-in out-out RNU Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUBE 3.42 Inactive DFGin BLAminus in-in out-out RNU Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUCE 3.85 Active DFGin BLAminus in-in in-in RKO Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUEE 3.25 Active DFGin BLAminus in-in in-in RVU Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUFE 3.3 Active DFGin BLAminus in-in in-in RW6 Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUHE 3.79 Active DFGin BLAminus in-in in-in RR9 Type1 715 - 1034 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUIE 3.5 Inactive DFGin BLAminus in-out in-out RV6 Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUJE 3.62 Inactive DFGin BLAminus in-out in-in RUW Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUKE 3.41 Active DFGin BLAminus in-in in-in RWE Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BULE 3.4 Active DFGin BLAminus in-in in-in RSU Type1 715 - 1038 None X893 0
Homo sapiens CDK12_HUMAN 8BUME 3.36 Active DFGin BLAminus in-in in-in T6X Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUNE 3.08 Active DFGin BLAminus in-in in-in RNF Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUOE 3.58 Active DFGin BLAminus in-in in-in RLC Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUPB 3.41 Active DFGin BLAminus in-in in-in RWN Type1 715 - 1027 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUPE 3.41 Inactive DFGin BLAminus in-in in-out RWN Type1 715 - 1027 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUPH 3.41 Active DFGin BLAminus in-in in-in RWN Type1 715 - 1028 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUQB 3.2 Active DFGin BLAminus in-in in-in RQ9 Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUQE 3.2 Active DFGin BLAminus in-in in-in RQ9 Type1 715 - 1027 K965R X893 0
Homo sapiens CDK12_HUMAN 8BURB 3.64 Active DFGin BLAminus in-in in-in RQU Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUSB 3.26 Active DFGin BLAminus in-in in-in RMX Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUTE 3.25 Active DFGin BLAminus in-in in-in RQ5 Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 4NSTA 2.2 Active DFGin BLAminus in-in in-in ADP Type1 716 - 1046 None X893 0
Homo sapiens CDK12_HUMAN 4NSTC 2.2 Active DFGin BLAminus in-in in-in ADP Type1 717 - 1045 None X893 1
Homo sapiens CDK12_HUMAN 6CKXA 2.8 Active DFGin BLAminus in-in in-in 8M1 Type1 722 - 1024 None X893 0
Homo sapiens CDK12_HUMAN 6CKXC 2.8 Active DFGin BLAminus in-in in-in 8M1 Type1 722 - 1024 None X893 0
Homo sapiens CDK12_HUMAN 7NXKC 3.0 None DFGin BLAminus in-none in-in UUB Type1 717 - 1040 None X893 0
Homo sapiens CDK12_HUMAN 8P81A 2.68 Active DFGin BLAminus in-in in-in RMF Type1 716 - 1035 None X893 0
Homo sapiens CDK12_HUMAN 8BUGH 3.53 Inactive DFGin None in-out in-in No_ligand No_ligand 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU1B 2.98 Inactive DFGin None in-in in-in RQL Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU1H 2.98 Inactive DFGin None in-in in-in RQL Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU2B 3.13 Inactive DFGin None in-in in-in RVQ Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU3B 3.42 Inactive DFGin None in-in in-in RSI Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU3H 3.42 Inactive DFGin None in-in in-in RSI Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU5E 3.134 Inactive DFGin None in-out in-in RMF Type1 713 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU6B 3.45 Inactive DFGin None in-in in-in RQE Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU6H 3.45 Inactive DFGin None in-out in-in RQE Type1 715 - 1038 K965R X893 0
Homo sapiens CDK12_HUMAN 8BU9B 3.51 Inactive DFGin None in-in in-in RRC Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUBH 3.42 Inactive DFGin None in-in out-in RNU Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUCH 3.85 Inactive DFGin None in-in in-in RKO Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUEB 3.25 Inactive DFGin None in-in in-in RVU Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUFB 3.3 Inactive DFGin None in-in in-in RW6 Type1 715 - 1033 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUFH 3.3 Inactive DFGin None in-out in-in RW6 Type1 715 - 1032 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUGB 3.53 Inactive DFGin None in-in in-in RPW Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUHB 3.79 Inactive DFGin None in-in in-in RR9 Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUHH 3.79 Inactive DFGin None in-in in-in RR9 Type1 715 - 1033 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUJB 3.62 Inactive DFGin None in-in in-in RUW Type1 715 - 1041 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUJH 3.62 Inactive DFGin None in-in in-in RUW Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUKB 3.41 Inactive DFGin None in-in in-in RWE Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUKH 3.41 Inactive DFGin None in-in in-in RWE Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BULB 3.4 Inactive DFGin None in-in in-in RSU Type1 715 - 1039 None X893 0
Homo sapiens CDK12_HUMAN 8BUMB 3.36 Inactive DFGin None in-in in-in T6X Type1 715 - 1040 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUMH 3.36 Inactive DFGin None in-out in-in T6X Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUOH 3.58 Inactive DFGin None in-in in-in RLC Type1 715 - 1044 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUQH 3.2 Inactive DFGin None in-in in-in RQ9 Type1 715 - 1035 K965R X893 0
Homo sapiens CDK12_HUMAN 8BURH 3.64 Inactive DFGin None in-in in-in RQU Type1 715 - 1039 K965R X893 0
Homo sapiens CDK12_HUMAN 8BUSE 3.26 Inactive DFGin None in-in in-in RMX Type1 715 - 1043 K965R X893 0
Homo sapiens CDK12_HUMAN 9FMRB 3.9 Inactive DFGin None in-out in-in RMF Type1 714 - 1047 None X893 0

CDK12 (Cyclin-dependent kinase 12)

No non-human structures known.