TKL_RIPK2 (Receptor-interacting serine/threonine-protein kinase 2)

Total number of chains: 72
Active chains: 1
Uniprot: RIPK2_HUMAN
Kinase Domain Residues: 18 - 292
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 47 65.3% AF-O43353-K3A
DFGin BLBplus 10 13.9% 5NG3A
DFGin None 6 8.3% 6FU5B
DFGin BLBminus 3 4.2% 6S1FA
DFGout BBAminus 3 4.2% 6ES0A
DFGout None 3 4.2% 5AR7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O43353-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2
5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2
5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
AF-O43353-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2
8AZAA 3.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
8AZAB 3.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR2A 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR2B 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OA 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OB 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OC 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OD 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OE 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OF 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OG 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OH 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OI 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OJ 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OK 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OL 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OM 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5ON 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OO 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5OP 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6HMXA 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6HMXB 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6SZEB 2.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6SZJB 2.53 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nioo M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6FU5A 3.26 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
6S1FB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
6S1FD 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR5A 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR5B 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5J79A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GE Type1 2 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5J79B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 6GE Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5NG2A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2
5NG2B 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2
6UL8A 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
6UL8B 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
6RN8A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6RN8B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6RNAA 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6RNAB 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
8X2OA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
8X2OB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2
5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2
6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5JA 2.85 Inactive DFGin‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
5W5JB 2.85 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 10 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 2
6FU5B 3.26 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
9F3VA 1.943 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2
9F3VB 1.943 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR8A 2.79 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
4C8BA 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoni APEdist_nnno 0LI Type2 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
4C8BB 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 0LI Type2 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
5AR7A 2.71 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2

TKL_RIPK2 (Receptor-interacting serine/threonine-protein kinase 2)

Total number of chains: 72
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 47 65.3% AF-O43353-K3A
DFGin BLBplus 10 13.9% 5NG3A
DFGin None 6 8.3% 6FU5B
DFGin BLBminus 3 4.2% 6S1FA
DFGout BBAminus 3 4.2% 6ES0A
DFGout None 3 4.2% 5AR7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
RIPK2_HUMAN AF-O43353-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG0A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ACP ATPlike 6 - 300 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG0B 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii ACP ATPlike 5 - 299 0 None L294F Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR3A 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR3B 3.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ACP ATPlike 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN AF-O43353-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii No_ligand No_ligand 10 - 300 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 8AZAA 3.15 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 8AZAB 3.15 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 8 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR2A 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR2B 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OA 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OB 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OC 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OD 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OE 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OF 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OG 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OH 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OI 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OJ 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OK 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OL 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OM 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5ON 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OO 2.89 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5OP 2.89 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_nnno 9XA Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6HMXA 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6HMXB 2.53 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo GEZ Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6SZEB 2.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6SZJB 2.53 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nioo M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6FU5A 3.26 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6S1FB 3.11 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6S1FD 3.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR5A 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR5B 2.66 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn IQ7 Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5J79A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GE Type1 2 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5J79B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 6GE Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG2A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG2B 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 5 - 298 0 None D146N Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6UL8A 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6UL8B 2.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6RN8A 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6RN8B 2.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6RNAA 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6RNAB 2.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 8X2OA 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 8X2OB 2.26 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG3A 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 8 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG3B 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnoo No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG3C 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 9 - 297 0 None K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5NG3D 2.6 Inactive DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaioi APEdist_nooo No_ligand No_ligand 9 - 297 0 TPO111 K47R Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6SZEA 2.94 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn M2B Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6SZJA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno M5W Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR4A 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn SB2 Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR4B 2.7 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SB2 Type1 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5J7BA 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 6GD Type1 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5J7BB 2.53 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaioi APEdist_nooo 6GD Type1 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5JA 2.85 Inactive DFGin‑None none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5W5JB 2.85 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 9WS Type1 10 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6FU5B 3.26 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno E7N Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 9F3VA 1.943 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 314 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 9F3VB 1.943 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H90 Type1 9 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR8A 2.79 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 4C8BA 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoni APEdist_nnno 0LI Type2 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 4C8BB 2.75 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 0LI Type2 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
RIPK2_HUMAN 5AR7A 2.71 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens

TKL_RIPK2 (Receptor-interacting serine/threonine-protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism