CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 175
Active chains: 12
Uniprot: MK01_HUMAN
Kinase Domain Residues: 25 - 313
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 172 98.3% AF-P28482-K1A
DFGin ABAminus 3 1.7% 1WZYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
AF-P28482-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 321 0 None None Mitogen-activated protein kinase 1
AF-P28482-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 321 0 None None Mitogen-activated protein kinase 1
5V61A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 359 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
6OPHA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QB Type1 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
8U8JA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WAL Type1 7 - 358 0 TPO185,PTR187 A7S Mitogen-activated protein kinase 1
8U8KA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W8U Type1 10 - 358 0 TPO185,PTR187 A7S Mitogen-activated protein kinase 1
4QTEA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 390 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
6G54A 2.05 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6H3 Type1 10 - 356 0 None None Mitogen-activated protein kinase 1
7OPMA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 08G Type1 1 - 360 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
5V62A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FRZ, AKS Type1, Type1 10 - 360 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
8PVUE 3.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 24 - 356 0 None None Mitogen-activated protein kinase 1
1WZYA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoio APEdist_oioo F29 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
1TVOA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FRZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
4H3QA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo ANP ATPlike 9 - 360 0 None R77A,C161S,I255G,E314A Mitogen-activated protein kinase 1
4IZ5A 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
4IZ5B 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
4IZ5C 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
4IZ5D 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1
2Y9QA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1
4FMQA 2.098 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1
4NIFB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 360 0 None None Mitogen-activated protein kinase 1
4NIFE 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 360 0 None None Mitogen-activated protein kinase 1
8PSRA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 1 - 358 0 None None Mitogen-activated protein kinase 1
3TEIA 2.404 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 358 0 None R77A,E314A Mitogen-activated protein kinase 1
4H3PA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1
4H3PD 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1
8PSTA 1.9 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnno AN2, DC6 ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1
8PSWA 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nioo AN2, D2I ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1
8PSYA 2.55 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_oioo AN2, EI0 ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1
8PT0A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo ANP, EAI ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1
8PT1A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP, E2A ATPlike, Allosteric 11 - 359 0 None None Mitogen-activated protein kinase 1
8PT5A 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP, D5R ATPlike, Allosteric 10 - 358 0 None None Mitogen-activated protein kinase 1
8R5FA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ANP, Y3H ATPlike, Allosteric 11 - 359 0 None None Mitogen-activated protein kinase 1
7W5OB 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GI Allosteric 12 - 357 0 None None Mitogen-activated protein kinase 1
8PT3A 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_oiio D7O, ANP Allosteric, ATPlike 10 - 359 0 None None Mitogen-activated protein kinase 1
6QAHA 1.58 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVB, HVB Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1
6QALA 1.57 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HV2, HV2 Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1
6NBSA 1.9 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii KJ7, KJ4 Allosteric, Allosteric 10 - 356 0 None None Mitogen-activated protein kinase 1
8AOGA 1.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii N29, N29, N29 Allosteric, Allosteric, Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
6G8XA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi EQT, EQT Allosteric, Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
6QA1A 1.58 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVK, HVK, HVK, HVK, HVK, HVK, HVK Allosteric, Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1
6QA4A 1.6 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi HRZ, HRZ, HRZ, HRZ Allosteric, Type1, Allosteric, Type3 11 - 357 0 None None Mitogen-activated protein kinase 1
4IZ7A 1.8 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 11 - 360 0 None None Mitogen-activated protein kinase 1
4IZ7C 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 11 - 359 0 None None Mitogen-activated protein kinase 1
4IZAA 1.93 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
4IZAC 1.93 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
6Q7SA 1.73 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 11 - 356 0 None None Mitogen-activated protein kinase 1
6QA3A 1.57 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 8 - 357 0 None None Mitogen-activated protein kinase 1
4QP2B 2.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 12 - 357 0 None None Mitogen-activated protein kinase 1
7E73A 2.28 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 11 - 357 0 None Y36H Mitogen-activated protein kinase 1
7E75A 2.481 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 10 - 358 0 None G37C Mitogen-activated protein kinase 1
6D5YA 2.86 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 13 - 357 0 None G169D Mitogen-activated protein kinase 1
1PMEA 2.0 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii SB2 Type1 16 - 360 0 None I103L,Q105T,D106H,E109G,T110A Mitogen-activated protein kinase 1
6DMGA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK6 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
4XJ0A 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 41B Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4XJ0B 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 41B Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
8ZJVA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID Type1 10 - 358 0 None None Mitogen-activated protein kinase 1
5K4IA 1.76 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn 6QB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
3SA0A 1.595 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NRA Type1 4 - 360 0 None None Mitogen-activated protein kinase 1
4FUXA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii E75 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
4FUYA 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK2 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
4FV0A 2.1 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK3 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
4FV1A 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK4 Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
4FV2A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK5 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
4FV3A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK6 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
4FV7A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E94 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
4G6NA 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK0 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
4G6OA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E28 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
4N0SA 1.799 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DHC Type1 6 - 357 0 None None Mitogen-activated protein kinase 1
4ZXTA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii CAQ Type1 7 - 357 0 None None Mitogen-activated protein kinase 1
5LCKA 1.89 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6TT Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
5LCJA 1.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6TS Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
6G91A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EQW Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
6G92A 1.99 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
6G93A 1.67 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EU2 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
6G97A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EQZ Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
6G9AA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESQ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
6G9MA 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESW Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
6GDQA 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EVK Type1 10 - 357 0 None None Mitogen-activated protein kinase 1
6GJBA 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F0H Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
6Q7KA 1.84 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 2AI Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
6QAWA 1.84 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii HVE Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
6RQ4A 1.96 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii KE8 Type1 19 - 357 0 None None Mitogen-activated protein kinase 1
7NR3A 1.897 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UO5 Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AO2A 1.796 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi NXI Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
8AO3A 1.778 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NYX Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
8AO4A 1.825 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N8U Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
8AO5A 1.595 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N6K Type1 15 - 356 0 None None Mitogen-activated protein kinase 1
8AO6A 1.811 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N9F Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AO7A 1.61 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N3X Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AO8A 1.697 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N5U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AO9A 1.624 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii N4F Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOBA 1.623 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NB3 Type1 18 - 356 0 None None Mitogen-activated protein kinase 1
8AOCA 1.62 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N3O Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOEA 1.687 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N6U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOFA 1.615 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N4U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOJA 1.12 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii N8L Type1 10 - 356 0 None None Mitogen-activated protein kinase 1
3W55A 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnoo 1FM Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
5AX3A 2.984 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aanii APEdist_iion 5ID Type1 10 - 358 0 None None Mitogen-activated protein kinase 1
7W5OA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID Type1 11 - 360 0 None None Mitogen-activated protein kinase 1
7XC1B 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4O6EA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 2SH Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
4QP1A 2.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi EMU Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4QP1B 2.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi EMU Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP2A 2.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 36R Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4QP3A 2.599 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioi 36Q Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4QP3B 2.599 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 36Q Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP4A 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo 36O Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
4QP4B 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo 36O Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP6A 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 36N Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4QP6B 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 36N Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP7A 2.249 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 363 Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
4QP7B 2.249 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo 363 Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP8A 2.446 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo 362 Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QP8B 2.446 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 362 Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
4QP9A 2.001 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 35X Type1 13 - 357 0 None None Mitogen-activated protein kinase 1
4QPAA 2.85 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 35W Type1 12 - 357 0 None None Mitogen-activated protein kinase 1
4QPAB 2.85 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi 35W Type1 12 - 360 0 None None Mitogen-activated protein kinase 1
4ZZMA 1.89 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi CQ6 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
4ZZNA 1.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii CQ8 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
4ZZOA 1.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi CQ3 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
2OJGA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 19A Type1 19 - 357 0 None None Mitogen-activated protein kinase 1
2OJIA 2.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 33A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1
2OJJA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 82A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1
9LNRA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn A1EKR Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
5NGUA 2.74 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8X2 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
5NHFA 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 8X5 Type1 12 - 355 0 None None Mitogen-activated protein kinase 1
5NHHA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XH Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
5NHJA 2.12 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XE Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
5NHLA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XB Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
5NHOA 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XN Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
5NHPA 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XK Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
5NHVA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8QB Type1 11 - 355 0 None None Mitogen-activated protein kinase 1
6SLGA 1.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii LHZ Type1 18 - 356 0 None None Mitogen-activated protein kinase 1
5WP1A 1.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii B7S, BEZ Type1, Allosteric 15 - 357 0 None None Mitogen-activated protein kinase 1
6Q7TA 1.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HOW, HOW Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1
6QAGA 2.07 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii HUH, HUH Type1, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1
8AOAA 1.62 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N83, OZU Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1
8AODA 1.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii NY0, NYI Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOHA 1.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N96, N96 Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1
8AOIA 1.602 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NX0, NX0 Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1
7XC1A 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID, B8Z Type1, Allosteric 10 - 360 0 None None Mitogen-activated protein kinase 1
7X4UA 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID, 8DK, BTB Type1, Allosteric, Allosteric 10 - 359 0 None None Mitogen-activated protein kinase 1
4QTAA 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 38Z Type1.5_Front 10 - 358 0 None None Mitogen-activated protein kinase 1
6G9DA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ER8 Type1.5_Front 8 - 357 0 None None Mitogen-activated protein kinase 1
6G9HA 1.73 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERW Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
6G9JA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERK Type1.5_Front 8 - 357 0 None None Mitogen-activated protein kinase 1
6G9KA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESK Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
6G9NA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi ESN Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
6GDMA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F3Z Type1.5_Front 8 - 356 0 None None Mitogen-activated protein kinase 1
6GE0A 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EVQ Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
6GJDA 1.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F0E Type1.5_Front 10 - 357 0 None None Mitogen-activated protein kinase 1
7AUVA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYW Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
7NQQA 1.943 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UMN Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1
7NQWA 1.775 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UNW Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1
7NR5A 1.766 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi UOH Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1
7NR8A 1.627 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UOE Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1
7NR9A 1.906 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii UOW Type1.5_Front 11 - 355 0 None None Mitogen-activated protein kinase 1
6QAQA 1.58 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii HVQ, HVQ Type3, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1
4FV4A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii EK7 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
4FV5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni EK9 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
4FV6A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E57 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1
4FV8A 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii E63 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
4FV9A 2.11 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E71 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
5BUEA 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V8 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
5BUIA 2.12 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V9 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1
5BUJA 1.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
5BVDA 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VF Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
5BVEA 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VG Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
5BVFA 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 4VJ Type1 9 - 358 0 None None Mitogen-activated protein kinase 1
3I5ZA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii Z48 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1
3I60A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E86 Type1 8 - 358 0 None None Mitogen-activated protein kinase 1
6OPIA 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn N0V Type1.5_Front 10 - 356 0 TPO185,PTR187 None Mitogen-activated protein kinase 1

CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 256
Active chains: 16
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 250 97.7% AF-P28482-K1A
DFGin ABAminus 3 1.2% 1WZYA
DFGin None 1 0.4% 6FJZA
DFGout None 1 0.4% 4I5HA
None None 1 0.4% 6RFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MK01_HUMAN 6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN AF-P28482-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 321 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN AF-P28482-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 17 - 321 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5V61A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 10 - 359 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6OPHA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QB Type1 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8U8JA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii WAL Type1 7 - 358 0 TPO185,PTR187 A7S Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8U8KA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W8U Type1 10 - 358 0 TPO185,PTR187 A7S Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QTEA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 390 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G54A 2.05 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6H3 Type1 10 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7OPMA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 08G Type1 1 - 360 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5V62A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FRZ, AKS Type1, Type1 10 - 360 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PVUE 3.5 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 24 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 1WZYA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaoio APEdist_oioo F29 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 1TVOA 2.5 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii FRZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4H3QA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_iioo ANP ATPlike 9 - 360 0 None R77A,C161S,I255G,E314A Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ5A 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ5B 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ5C 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ5D 3.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo ADP ATPlike 11 - 357 0 None T185E Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 2Y9QA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FMQA 2.098 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4NIFB 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4NIFE 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PSRA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 1 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 3TEIA 2.404 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 10 - 358 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4H3PA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4H3PD 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 11 - 359 0 None R77A,E314A Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PSTA 1.9 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_nnno AN2, DC6 ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PSWA 2.0 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nioo AN2, D2I ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PSYA 2.55 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_oioo AN2, EI0 ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PT0A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oioo ANP, EAI ATPlike, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PT1A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP, E2A ATPlike, Allosteric 11 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PT5A 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP, D5R ATPlike, Allosteric 10 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8R5FA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnno ANP, Y3H ATPlike, Allosteric 11 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7W5OB 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 6GI Allosteric 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8PT3A 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_oiio D7O, ANP Allosteric, ATPlike 10 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QAHA 1.58 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVB, HVB Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QALA 1.57 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HV2, HV2 Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6NBSA 1.9 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii KJ7, KJ4 Allosteric, Allosteric 10 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOGA 1.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii N29, N29, N29 Allosteric, Allosteric, Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G8XA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi EQT, EQT Allosteric, Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QA1A 1.58 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVK, HVK, HVK, HVK, HVK, HVK, HVK Allosteric, Type1, Allosteric, Allosteric, Allosteric, Allosteric, Allosteric 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QA4A 1.6 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iioi HRZ, HRZ, HRZ, HRZ Allosteric, Type1, Allosteric, Type3 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ7A 1.8 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 11 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZ7C 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 11 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZAA 1.93 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4IZAC 1.93 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 11 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6Q7SA 1.73 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QA3A 1.57 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP2B 2.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi No_ligand No_ligand 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7E73A 2.28 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 11 - 357 0 None Y36H Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7E75A 2.481 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 10 - 358 0 None G37C Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6D5YA 2.86 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 13 - 357 0 None G169D Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 1PMEA 2.0 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii SB2 Type1 16 - 360 0 None I103L,Q105T,D106H,E109G,T110A Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6DMGA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK6 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4XJ0A 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 41B Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4XJ0B 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 41B Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8ZJVA 1.8 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID Type1 10 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5K4IA 1.76 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn 6QB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 3SA0A 1.595 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NRA Type1 4 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FUXA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii E75 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FUYA 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK2 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV0A 2.1 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK3 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV1A 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK4 Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV2A 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK5 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV3A 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EK6 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV7A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E94 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4G6NA 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii EK0 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4G6OA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E28 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4N0SA 1.799 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DHC Type1 6 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4ZXTA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii CAQ Type1 7 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5LCKA 1.89 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6TT Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5LCJA 1.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6TS Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G91A 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EQW Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G92A 1.99 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERZ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G93A 1.67 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EU2 Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G97A 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EQZ Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9AA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESQ Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9MA 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESW Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6GDQA 1.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EVK Type1 10 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6GJBA 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F0H Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6Q7KA 1.84 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 2AI Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QAWA 1.84 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii HVE Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6RQ4A 1.96 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii KE8 Type1 19 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NR3A 1.897 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UO5 Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO2A 1.796 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi NXI Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO3A 1.778 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NYX Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO4A 1.825 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N8U Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO5A 1.595 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N6K Type1 15 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO6A 1.811 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N9F Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO7A 1.61 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N3X Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO8A 1.697 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N5U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AO9A 1.624 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii N4F Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOBA 1.623 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NB3 Type1 18 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOCA 1.62 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N3O Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOEA 1.687 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N6U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOFA 1.615 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N4U Type1 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOJA 1.12 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii N8L Type1 10 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 3W55A 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnoo 1FM Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5AX3A 2.984 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aanii APEdist_iion 5ID Type1 10 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7W5OA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID Type1 11 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7XC1B 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4O6EA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 2SH Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP1A 2.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooi EMU Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP1B 2.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi EMU Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP2A 2.23 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 36R Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP3A 2.599 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nioi 36Q Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP3B 2.599 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 36Q Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP4A 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo 36O Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP4B 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo 36O Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP6A 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 36N Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP6B 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 36N Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP7A 2.249 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 363 Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP7B 2.249 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo 363 Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP8A 2.446 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo 362 Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP8B 2.446 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 362 Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QP9A 2.001 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 35X Type1 13 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QPAA 2.85 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 35W Type1 12 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QPAB 2.85 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi 35W Type1 12 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4ZZMA 1.89 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi CQ6 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4ZZNA 1.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii CQ8 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4ZZOA 1.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi CQ3 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 2OJGA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 19A Type1 19 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 2OJIA 2.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 33A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 2OJJA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 82A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 9LNRA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn A1EKR Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NGUA 2.74 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8X2 Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHFA 2.14 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 8X5 Type1 12 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHHA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XH Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHJA 2.12 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XE Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHLA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XB Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHOA 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XN Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHPA 1.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8XK Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5NHVA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 8QB Type1 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6SLGA 1.33 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii LHZ Type1 18 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5WP1A 1.4 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii B7S, BEZ Type1, Allosteric 15 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6Q7TA 1.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HOW, HOW Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QAGA 2.07 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii HUH, HUH Type1, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOAA 1.62 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N83, OZU Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AODA 1.62 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii NY0, NYI Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOHA 1.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii N96, N96 Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 8AOIA 1.602 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii NX0, NX0 Type1, Allosteric 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7XC1A 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID, B8Z Type1, Allosteric 10 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7X4UA 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID, 8DK, BTB Type1, Allosteric, Allosteric 10 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4QTAA 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 38Z Type1.5_Front 10 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9DA 1.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ER8 Type1.5_Front 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9HA 1.73 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERW Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9JA 1.98 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ERK Type1.5_Front 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9KA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ESK Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6G9NA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi ESN Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6GDMA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F3Z Type1.5_Front 8 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6GE0A 1.82 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EVQ Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6GJDA 1.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F0E Type1.5_Front 10 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7AUVA 1.76 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYW Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NQQA 1.943 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UMN Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NQWA 1.775 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UNW Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NR5A 1.766 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi UOH Type1.5_Front 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NR8A 1.627 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii UOE Type1.5_Front 11 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 7NR9A 1.906 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii UOW Type1.5_Front 11 - 355 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6QAQA 1.58 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii HVQ, HVQ Type3, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV4A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii EK7 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV5A 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni EK9 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV6A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E57 Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV8A 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii E63 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 4FV9A 2.11 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E71 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BUEA 2.4 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V8 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BUIA 2.12 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4V9 Type1 11 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BUJA 1.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VB Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BVDA 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VF Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BVEA 2.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 4VG Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 5BVFA 1.9 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 4VJ Type1 9 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 3I5ZA 2.2 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii Z48 Type1 8 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 3I60A 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnni E86 Type1 8 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
MK01_HUMAN 6OPIA 3.0 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn N0V Type1.5_Front 10 - 356 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
MK01_RAT 3ZUVA 2.72 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ZUVC 2.72 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2ERKA 2.4 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OPKA 2.54 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 390 Type1 9 - 354 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S33A 1.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 355 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S32A 1.34 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GT3A 1.68 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GVAA 1.83 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 7UGBA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S34A 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 1GOLA 2.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 2 - 358 0 None K52R Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQVA 2.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_oiii ANP ATPlike 4 - 354 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQXA 1.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 353 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQWA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 354 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6RFPA 1.74 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 353 0 None K229T,H230D,Y231H Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S2ZA 1.48 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 354 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3R63A 1.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 358 0 None S246E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OT6A 1.65 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 9 - 356 0 None D319N Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OTSA 2.1 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 7 - 356 0 None E320K Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3O71A 1.95 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S31A 1.45 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2FYSA 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 8 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2FYSB 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 8 - 357 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GSBA 1.8 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5UMOA 2.26 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ZU7A 1.97 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 10 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2GPHA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 10 - 354 0 None T116C Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S30A 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 355 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RLXA 1.6 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 4 - 355 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RMBA 1.55 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 4 - 355 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RM2A 1.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 4 - 355 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XNEA 1.8 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii TT4 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XRJA 1.69 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 620 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XOYA 2.1 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aaiii APEdist_nnni DX4 Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP0A 1.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 42A Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP2A 1.748 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii TT4 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP3A 1.782 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi DX4 Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XRLA 2.554 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 42A Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3C9WB 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ERKA 2.1 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii SB4 Type1 6 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3QYWA 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 6PB Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3QYZA 1.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi Z8B Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4ERKA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii OLO Type1 6 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FI3A 1.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DJ2 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FI6A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DF8 Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJ0A 1.659 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A3N Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJBA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii AOC Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FLEA 1.48 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii DQ2 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FLVA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DTW Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FMAA 1.667 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DU8 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FN5A 1.932 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii DVZ Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FQ7A 1.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi E2K Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FR1A 1.561 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi E3K Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FRPA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ZAS Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FXVA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii E9W Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR2A 1.64 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WNT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR3A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WNC Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR4A 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WN8 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR5A 1.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WMC Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR6A 1.65 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMN Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR7A 1.51 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMI Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR8A 1.61 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WN2 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR9A 1.94 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMX Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRAA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WM6 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRBA 1.51 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WLZ Type1 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRCA 1.69 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii WMT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2Z7LA 2.41 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii S91 Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5KE0A 1.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6S9 Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5U6IA 1.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 81Y Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5HD7A 1.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1 9 - 355 0 None G167D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4N4SA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4N4SB 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XOZA 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 620 Type1.5_Front 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4QYYA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 3G7 Type1.5_Front 13 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5HD4A 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 9 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6CPWA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8V Type1.5_Front 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6DCGA 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G67 Type1.5_Front 16 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJZA 1.864 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DKW Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4I5HA 1.9 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioo G17 Type2 9 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6RFOA 1.7 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 12 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3C9WA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus

CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 81
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 78 96.3% 4S32A
DFGin None 1 1.2% 6FJZA
DFGout None 1 1.2% 4I5HA
None None 1 1.2% 6RFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MK01_RAT 3ZUVA 2.72 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ZUVC 2.72 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2ERKA 2.4 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 358 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OPKA 2.54 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 390 Type1 9 - 354 0 TPO183,PTR185 None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S33A 1.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 355 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S32A 1.34 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GT3A 1.68 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GVAA 1.83 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 7UGBA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo ANP ATPlike 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S34A 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ANP ATPlike 4 - 354 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 1GOLA 2.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaiii APEdist_oiii ATP ATPlike 2 - 358 0 None K52R Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQVA 2.19 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaini APEdist_oiii ANP ATPlike 4 - 354 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQXA 1.7 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 353 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RQWA 1.8 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_oiii ANP ATPlike 4 - 354 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6RFPA 1.74 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 353 0 None K229T,H230D,Y231H Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S2ZA 1.48 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 354 0 None R65S Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3R63A 1.7 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 358 0 None S246E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OT6A 1.65 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 9 - 356 0 None D319N Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6OTSA 2.1 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaooo APEdist_iioo No_ligand No_ligand 7 - 356 0 None E320K Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3O71A 1.95 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S31A 1.45 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2FYSA 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 8 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2FYSB 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iioo No_ligand No_ligand 8 - 357 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4GSBA 1.8 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5UMOA 2.26 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ZU7A 1.97 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioo No_ligand No_ligand 10 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2GPHA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 10 - 354 0 None T116C Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4S30A 2.0 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 4 - 355 0 None I84A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RLXA 1.6 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aaini APEdist_iiii No_ligand No_ligand 4 - 355 0 None T188A Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RMBA 1.55 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 4 - 355 0 None R65S,T188D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8RM2A 1.55 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 4 - 355 0 None T188E Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XNEA 1.8 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii TT4 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XRJA 1.69 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 620 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XOYA 2.1 Inactive DFGin‑BLAminus out-out in-none nonTYR APEdihe_aaiii APEdist_nnni DX4 Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP0A 1.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 42A Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP2A 1.748 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii TT4 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XP3A 1.782 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi DX4 Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XRLA 2.554 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 42A Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3C9WB 2.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aanoi APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3ERKA 2.1 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii SB4 Type1 6 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3QYWA 1.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi 6PB Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3QYZA 1.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi Z8B Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4ERKA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii OLO Type1 6 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FI3A 1.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DJ2 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FI6A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DF8 Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJ0A 1.659 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi A3N Type1 9 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJBA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii AOC Type1 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FLEA 1.48 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii DQ2 Type1 8 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FLVA 1.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DTW Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FMAA 1.667 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi DU8 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FN5A 1.932 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii DVZ Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FQ7A 1.6 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi E2K Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FR1A 1.561 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioi E3K Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FRPA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii ZAS Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FXVA 1.53 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii E9W Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR2A 1.64 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WNT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR3A 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WNC Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR4A 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WN8 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR5A 1.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WMC Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR6A 1.65 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMN Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR7A 1.51 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMI Type1 9 - 357 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR8A 1.61 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WN2 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QR9A 1.94 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_iioi WMX Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRAA 1.55 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WM6 Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRBA 1.51 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi WLZ Type1 9 - 356 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 8QRCA 1.69 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii WMT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 2Z7LA 2.41 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii S91 Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5KE0A 1.68 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6S9 Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5U6IA 1.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 81Y Type1 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5HD7A 1.69 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1 9 - 355 0 None G167D Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4N4SA 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4N4SB 2.2 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioi APEdist_nnno 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4XOZA 1.95 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 620 Type1.5_Front 8 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4QYYA 1.65 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 3G7 Type1.5_Front 13 - 353 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 5HD4A 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 9 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6CPWA 1.85 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F8V Type1.5_Front 16 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6DCGA 1.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii G67 Type1.5_Front 16 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6FJZA 1.864 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaiii APEdist_oiii DKW Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 4I5HA 1.9 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioo G17 Type2 9 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 6RFOA 1.7 Inactive None‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 12 - 355 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus
MK01_RAT 3C9WA 2.5 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn HMY Type1 6 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus