8YHW

MAP3K14 (Mitogen-activated protein kinase kinase kinase 14)
Group: STE
Uniprot: M3K14_HUMAN
Organism: Homo sapiens
Domain boundary: 399 - 653
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in AGS Type1 334 - 675 6
B Active DFGin BLAminus in-in in-in AGS Type1 334 - 675 7
C Active DFGin BLAminus in-in in-in AGS Type1 334 - 675 7
D Active DFGin BLAminus in-in in-in AGS PE8 Type1 Allosteric 334 - 675 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       338        348        358        368 
gkfsvEEYLV HALQGSVSSG QAHSLTSLAK TWAARGSRSR 
       378        388        398        408 
EPSPKTEDNE GVLLTEKLKP VDYEYREEVH WATHQLRLGR 
       418        428        438        448 
GSFGEVHRME DKQTGFQCAV KKVRLEVFRA EELMACAGLT 
       458        468        478        488 
SPRIVPLYGA VREGPWVNIF MELLEGGSLG QLVKEQGCLP 
       498        508        518        528 
EDRALYYLGQ ALEGLEYLHS RRILHGDVKA DNVLLSSDGS 
       538        548        558        568 
HAALCDFGHA VCLqpdglgk slltgdYIPG TETHMAPEVV 
       578        588        598        608 
LGRSCDAKVD VWSSCCMMLH MLNGCHPWTQ FFRGPLCLKI 
       618        628        638        648 
ASEPPPVREI PPSCAPLTAQ AIQEGLRKEP IHRVSAAELG 
       658        668        678 
GKVNRALQQV GGLKSPWRGE YKEPRHPppn q
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None