TYR_ZAP70 (Tyrosine-protein kinase ZAP-70)

Total number of chains: 5
Active chains: 2
Uniprot: ZAP70_HUMAN
Kinase Domain Residues: 337 - 595
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% AF-P43403-K1A
DFGin BLAplus 2 40.0% 2OZOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P43403-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 329 - 603 0 None None Tyrosine-protein kinase ZAP-70
AF-P43403-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 329 - 603 0 None None Tyrosine-protein kinase ZAP-70
1U59A 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao STU Type1 328 - 606 0 None None Tyrosine-protein kinase ZAP-70
2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70
4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70

TYR_ZAP70 (Tyrosine-protein kinase ZAP-70)

Total number of chains: 5
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% AF-P43403-K1A
DFGin BLAplus 2 40.0% 2OZOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
ZAP70_HUMAN AF-P43403-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 329 - 603 0 None None Tyrosine-protein kinase ZAP-70 Homo sapiens
ZAP70_HUMAN AF-P43403-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 329 - 603 0 None None Tyrosine-protein kinase ZAP-70 Homo sapiens
ZAP70_HUMAN 1U59A 2.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao STU Type1 328 - 606 0 None None Tyrosine-protein kinase ZAP-70 Homo sapiens
ZAP70_HUMAN 2OZOA 2.6 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nnnao APEdist_aaan ANP ATPlike 2 - 606 0 None Y315F,Y319F,D461N Tyrosine-protein kinase ZAP-70 Homo sapiens
ZAP70_HUMAN 4K2RA 3.0 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 2 - 606 0 None D461N Tyrosine-protein kinase ZAP-70 Homo sapiens

TYR_ZAP70 (Tyrosine-protein kinase ZAP-70)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism