CMGC_MAPK10 (Mitogen-activated protein kinase 10)

Total number of chains: 77
Active chains: 2
Uniprot: MK10_HUMAN
Kinase Domain Residues: 64 - 359
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 67 87.0% 7ORFA
DFGin None 4 5.2% 8VS0A
DFGin BLAminus 3 3.9% AF-P53779-K1A
DFGin BLBplus 3 3.9% 4H36A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P53779-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 56 - 367 0 None None Mitogen-activated protein kinase 10
AF-P53779-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 56 - 367 0 None None Mitogen-activated protein kinase 10
8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10
4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10
1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10
6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
4Z9LA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno ANP, 880 Allosteric, Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4KKGA 2.4 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
3FI2A 2.28 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JK1 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3FV8A 2.28 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno JK3 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2B1PA 1.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AIZ Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2R9SA 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
2R9SB 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
2EXCX 2.75 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno JNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3OY1A 1.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 589 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3RTPA 2.4 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 34I Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2O2UA 2.45 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 738 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2WAJA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SNB Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2ZDTA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo 46C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
2ZDUA 2.5 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 446 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3FI3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno JK2 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
3KVXA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnno FMY Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
3V6RA 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
3V6RB 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
3V6SA 2.97 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
3V6SB 2.97 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
1PMNA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 984 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
1PMUA 2.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iooo 9HP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
7ORFA 1.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0G3 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10
2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
2P33A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo J07 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3CGFA 3.0 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo JNF Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3CGOA 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo JNO Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3G90X 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J72 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3G9LX 2.2 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno J67 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3G9NA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J88 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4KKHA 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 1RQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4W4VA 2.01 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3H8 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4W4WA 1.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HJ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4W4XA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HN Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4W4YA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4Y5HA 2.055 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 519 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
4X21A 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
4X21B 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 47 - 400 0 None None Mitogen-activated protein kinase 10
6EKDA 2.1 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno B9K Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
6EMHC 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
6EMHD 1.76 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
4WHZA 1.79 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 3NL Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
3TTIA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo KBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
7KSIA 1.726 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3S Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
7KSJA 2.06 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3Y Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
7KSKA 1.84 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_onoo X3V Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
7S1NA 2.11 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 86C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
7YL1A 2.48 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo J6F Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8ENJA 2.81 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo WNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8VNXA 2.0 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8VO4A 2.07 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHE Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8VTFA 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
7OREA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0EI, 0EI Type1, Type1 44 - 402 0 None None Mitogen-activated protein kinase 10
8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10
2O0UA 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10
3DA6A 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo BZ9 Type1.5_Front 46 - 401 0 None None Mitogen-activated protein kinase 10
4U79A 2.23 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3EL Type1.5_Front 44 - 400 0 None None Mitogen-activated protein kinase 10
4H39A 1.992 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
4H36A 3.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
4H3BA 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
4H3BC 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10
3OXIA 2.2 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno SYY Type1 46 - 400 0 None None Mitogen-activated protein kinase 10
3PTGA 2.43 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 932 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10
1PMVA 2.5 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oioo 537 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10
8VS0A 2.46 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACT Type1 45 - 400 0 None None Mitogen-activated protein kinase 10

CMGC_MAPK10 (Mitogen-activated protein kinase 10)

Total number of chains: 77
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 67 87.0% 7ORFA
DFGin None 4 5.2% 8VS0A
DFGin BLAminus 3 3.9% AF-P53779-K1A
DFGin BLBplus 3 3.9% 4H36A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MK10_HUMAN AF-P53779-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 56 - 367 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN AF-P53779-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 56 - 367 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8WGFA 1.85 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 44 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4KKEA 2.2 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_oooo AMP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EQ9B 1.83 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ACP ATPlike 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 1JNKA 2.3 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo ANP ATPlike 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4Z9LA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno ANP, 880 Allosteric, Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4KKGA 2.4 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3FI2A 2.28 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JK1 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3FV8A 2.28 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno JK3 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2B1PA 1.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AIZ Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2R9SA 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2R9SB 2.4 Inactive DFGin‑ABAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 255 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2EXCX 2.75 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno JNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3OY1A 1.7 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 589 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3RTPA 2.4 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 34I Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2O2UA 2.45 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 738 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2WAJA 2.4 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SNB Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2ZDTA 2.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo 46C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2ZDUA 2.5 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 446 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3FI3A 2.2 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_nnno JK2 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3KVXA 2.4 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaini APEdist_nnno FMY Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3V6RA 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3V6RB 2.6 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno CQQ Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3V6SA 2.97 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3V6SB 2.97 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno 0F0 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 1PMNA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 984 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 1PMUA 2.7 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_iooo 9HP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7ORFA 1.7 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0G3 Type1 45 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2P33A 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo J07 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3CGFA 3.0 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_oooo JNF Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3CGOA 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo JNO Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3G90X 2.4 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J72 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3G9LX 2.2 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno J67 Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3G9NA 2.8 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo J88 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4KKHA 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 1RQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4W4VA 2.01 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3H8 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4W4WA 1.9 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HJ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4W4XA 2.65 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HN Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4W4YA 2.3 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3HQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4Y46A 2.04 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 4F2 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4Y5HA 2.055 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo 519 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4X21A 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4X21B 1.95 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 3WH Type1 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EKDA 2.1 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno B9K Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EMHC 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EMHD 1.76 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn BGE Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4WHZA 1.79 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 3NL Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3TTIA 2.2 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo KBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3TTJA 2.1 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno JBI Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7KSIA 1.726 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3S Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7KSJA 2.06 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo X3Y Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7KSKA 1.84 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_onoo X3V Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7S1NA 2.11 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo 86C Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7YL1A 2.48 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo J6F Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8ENJA 2.81 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaiii APEdist_oooo WNK Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8VNXA 2.0 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHQ Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8VO4A 2.07 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo WHE Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8VTFA 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACP Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 7OREA 2.18 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 0EI, 0EI Type1, Type1 44 - 402 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 2O0UA 2.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3DA6A 2.0 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo BZ9 Type1.5_Front 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4U79A 2.23 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3EL Type1.5_Front 44 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4H39A 1.992 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaoio APEdist_nnno No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4H36A 3.0 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4H3BA 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 4H3BC 2.08 Inactive DFGin‑BLBplus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3OXIA 2.2 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno SYY Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 3PTGA 2.43 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 932 Type1 46 - 401 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 1PMVA 2.5 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oioo 537 Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
MK10_HUMAN 8VS0A 2.46 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiii APEdist_oooo A1ACT Type1 45 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens

CMGC_MAPK10 (Mitogen-activated protein kinase 10)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism