Protein kinases with DFGinter conformation in complex with All ligands

Total number of genes: 44
Total number of chains: 215
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter BABtrans 0 1 0 0 4 0 2 0 16 1 7YC9A
DFGinter None 12 81 0 15 2 0 12 18 49 2 4U3YA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Group Gene UniprotID Protein PDB Reso Activity Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJB 2.9 Inactive None in-in out-in No_ligand No_ligand
AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJD 2.9 Inactive None in-in out-in No_ligand No_ligand
AGC RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOC 2.75 Inactive None none-none out-out ANP Type1
AGC RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOG 2.75 Inactive None out-out out-none ANP Type1
AGC RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 1VZOA 1.8 Inactive None out-out out-out No_ligand No_ligand
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76B 3.0 Inactive None none-none out-none ANP Type1
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78A 2.5 Inactive None none-none out-out ANP Type1
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78B 2.5 Inactive None none-none out-out ANP Type1
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A 3.0 Inactive None none-none out-in ANP ANP Type1 Allosteric
AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 2R5TA 1.9 Inactive None none-none out-out ANP Type1
AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDMA 2.6 Inactive None none-none out-out MMG Type1
AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDNA 3.1 Inactive None none-none out-out GMG Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6XKAA 2.65 Inactive None out-out out-out No_ligand No_ligand
CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVA 2.4 Inactive None out-out out-out ZZL Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVB 2.4 Inactive None out-out out-out ZZL Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVC 2.4 Inactive None out-out out-out ZZL Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVD 2.4 Inactive None out-out out-out ZZL Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5EW9A 2.181 Inactive None out-out out-out 5VC Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6C2RA 1.96 Inactive None out-none out-none EG7 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6C2TA 1.73 Inactive None out-out out-out EGJ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3W16A 2.8 Inactive None out-out out-out P9J Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2J50A 3.0 Inactive None out-out out-out 627 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2J50B 3.0 Inactive None out-out out-out 627 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4C3RA 2.79 Inactive None out-out out-out ACP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTRA 2.85 Inactive None out-out none-out 4RJ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6Z4YA 2.25 Inactive None out-out out-out Q7Q Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6C83B 2.55 Inactive None out-out none-out ACP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6CPGA 2.8 Inactive None out-out none-out 35R Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6CPGD 2.8 Inactive None out-out none-out 35R Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSOA 1.97 Inactive None out-out out-out 627 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSOD 1.97 Inactive None out-out out-none 627 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 1MUOA 2.9 Inactive None out-out none-out ADN Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2J4ZA 2.0 Inactive None out-out out-out 626 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UNZA 2.8 Inactive None out-out out-out 0BZ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UNZB 2.8 Inactive None out-out out-out 0BZ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UO6A 2.8 Inactive None out-out out-out 0BY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UO6B 2.8 Inactive None out-out out-out 0BY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOHA 2.8 Inactive None out-out out-out 0C4 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOHB 2.8 Inactive None out-out out-out 0C4 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOJA 2.9 Inactive None out-out out-out 0C5 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOJB 2.9 Inactive None out-out out-out 0C5 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOKA 2.951 Inactive None out-out out-out 0C6 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOKB 2.951 Inactive None out-out out-out 0C6 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOLA 2.4 Inactive None out-out out-out 0C7 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOLB 2.4 Inactive None out-out out-out 0C7 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3FDNA 1.9 Inactive None out-out out-out MMH Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3K5UA 2.35 Inactive None out-out out-out PFQ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4JBQA 2.3 Inactive None out-out out-out VX6 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3LAUA 2.1 Inactive None out-out none-none OFI Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4UZHA 2.0 Inactive None out-out none-none JVE Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3H0YA 2.5 Inactive None out-out none-none 48B Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10A 2.2 Inactive None out-out out-out 97B Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10B 2.2 Inactive None out-out out-out 97B Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10D 2.2 Inactive None out-out out-none 97B Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3P9JA 2.8 Inactive None out-out out-out P9J Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3W10A 2.7 Inactive None out-out out-out RO9 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 3R22A 2.9 Inactive None out-out out-out D37 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCA 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCB 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCC 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCD 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCE 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCF 2.6 Inactive None out-out out-none MPY Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 7FICA 2.32 Inactive None out-none none-out 5YZ Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 Inactive None out-out none-none ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 Inactive None out-out out-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 Inactive None out-out out-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 9BZGA 1.8 Inactive None out-out out-out OG0 Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 9BZLB 1.81 Inactive None out-out out-out OGR Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8PR7A 2.76 Inactive None out-out none-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTQA 2.8 Inactive None out-out out-out 4RM Type1.5_Back
CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTSA 2.9 Inactive None out-out none-none 4RK Type1.5_Back
CAMK AURKA AURKA_HUMAN Aurora kinase A 3EFWA 2.29 Inactive None out-none none-none AK8 Type1.5_Front
CAMK AURKA AURKA_HUMAN Aurora kinase A 3EFWB 2.29 Inactive None out-out none-none AK8 Type1.5_Front
CAMK AURKA AURKA_HUMAN Aurora kinase A 3O50A 2.0 Inactive None out-out none-none LJE Type1.5_Front
CAMK AURKA AURKA_HUMAN Aurora kinase A 3O50B 2.0 Inactive None out-out none-out LJE Type1.5_Front
CAMK AURKA AURKA_HUMAN Aurora kinase A 6HJJA 2.13 Inactive None out-out out-out G7T Type1.5_Front
CAMK AURKB AURKB_HUMAN Aurora kinase B 4AF3A 2.75 Inactive None out-out none-none VX6 Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FGBA 2.6 Inactive None out-out out-out No_ligand No_ligand
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 Inactive None out-out none-none ATP Type1
CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 Inactive None out-none none-out ATP Type1
CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FA 1.97 Inactive None out-out none-none MMW Type1
CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FB 1.97 Inactive None out-out none-none MMW Type1
CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T29AAA 1.484 Inactive None out-out none-none M8Z Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4OO 4.8 Inactive None in-none in-in No_ligand No_ligand
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4PH 6.6 Inactive None in-none in-in No_ligand No_ligand
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 3SOAA 3.55 Inactive None in-none in-in DB8 Type1
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4IXPA 2.749 Inactive BABtrans out-none out-out No_ligand No_ligand
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMTA 1.98 Inactive None out-out none-out 47W Type1
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMUA 2.02 Inactive None out-out none-out 0V0 Type1
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDA 2.95 Inactive None out-out out-none No_ligand No_ligand
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDB 2.95 Inactive None out-out out-none No_ligand No_ligand
CAMK TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEKA 2.8 Inactive None out-none none-none No_ligand No_ligand
CAMK TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEMA 2.1 Inactive None out-none none-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 Inactive None in-out none-out IRG 0OQ Allosteric Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 Inactive None in-in none-none SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5WJJA 1.6 Inactive None in-in out-out AQY Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6ANLA 2.0 Inactive None in-in none-out T75 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ML5A 1.9 Inactive None in-in none-none 1VI Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HUCA 1.8 Inactive None in-in none-out G97 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 Inactive None in-in none-out SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZSGA 1.89 Inactive None in-in none-out T75 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWTA 1.7 Inactive None in-in out-none GXH Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWUA 2.3 Inactive None in-in none-out GE5 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWVA 1.7 Inactive None in-in none-none GEW Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 Inactive None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYA 2.52 Inactive None in-out out-out OWQ Type1
CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYD 2.52 Inactive None out-out out-out OWQ Type1
CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCD 2.43 Inactive None out-out out-out OXW Type1
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive BABtrans out-none out-out No_ligand No_ligand
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive BABtrans out-out out-out No_ligand No_ligand
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive BABtrans out-none out-out CK7 Type1
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive BABtrans out-out out-out CK7 Type1
NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 Inactive None out-none none-out No_ligand No_ligand
NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 Inactive None out-out out-out AGS Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive BABtrans out-out out-out G41 Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 Inactive None out-out out-out G41 Type1
OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 8OMVE 4.16 Inactive None in-out out-out No_ligand No_ligand
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5YT3A 2.9 Inactive None out-out none-none ANP Type1
STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQA 2.3 Inactive BABtrans out-out in-in STU Type1
STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQB 2.3 Inactive BABtrans in-none in-in STU Type1
STE MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 9BI8A 2.25 Inactive None out-out out-out A1APL Type1
STE MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 9BI8B 2.25 Inactive None out-out out-out A1APL Type1
STE MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZA 2.09 Inactive None out-out out-out No_ligand No_ligand
STE MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3YA 1.45 Inactive None out-out out-out No_ligand No_ligand
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 9D50B 1.898 Inactive None in-out none-out A1A2T Type1
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFA 1.75 Inactive None out-out out-none 6UI Type1
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFB 1.75 Inactive None out-out out-in 6UI Type1
STE STK25 STK25_HUMAN Serine/threonine-protein kinase 25 4NZWB 3.583 Inactive None out-out none-in J60 Type1
STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZFB 3.64 Inactive None out-out out-out DKI Type1
STE TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88A 2.7 Inactive None out-out out-out No_ligand No_ligand
STE TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88B 2.7 Inactive None out-out out-out No_ligand No_ligand
TKL ILK ILK_HUMAN Scaffold protein ILK 3KMUA 1.8 Inactive None out-out out-out No_ligand No_ligand
TKL ILK ILK_HUMAN Scaffold protein ILK 6MIBA 1.8 Inactive None out-out out-out No_ligand No_ligand
TKL ILK ILK_HUMAN Scaffold protein ILK 3KMWA 2.0 Inactive None out-out out-out ATP Type1
TKL ILK ILK_HUMAN Scaffold protein ILK 3REPA 1.8 Inactive None out-out out-out ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 Inactive None out-out out-in ATP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8VH5A 4.0 Inactive None out-out out-in ANP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8VH5C 4.0 Inactive None out-out out-in ANP Type1
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 Inactive None out-out out-in ATP Type1
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3B 2.05 Inactive None out-out out-out No_ligand No_ligand
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3C 2.05 Inactive None out-none none-out No_ligand No_ligand
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3D 2.05 Inactive None out-out none-out No_ligand No_ligand
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XA 2.0 Inactive BABtrans in-out out-in 8DW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XB 2.0 Inactive BABtrans in-out out-in 8DW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYB 2.891 Inactive BABtrans in-out out-in 1N1 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA 2.2 Inactive None in-out out-in STI 1N1 Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC 2.2 Inactive None in-none out-in STI 1N1 Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FA 2.7 Inactive None in-out out-in No_ligand No_ligand
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8A 2.5 Inactive None in-out out-in PVB Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8B 2.5 Inactive None in-none out-in PVB Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7SA 1.946 Inactive None in-in out-in 6CI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7SB 1.946 Inactive None in-out out-in 6CI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7ZB 2.255 Inactive None in-in out-in 6CI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YA 2.2 Inactive None in-out out-in 8IW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YB 2.2 Inactive None in-out out-in 8IW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FA 2.45 Inactive None in-none out-in QEW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FB 2.45 Inactive None in-none out-in QEW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HA 2.278 Inactive None in-none out-in QH9 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HB 2.278 Inactive None in-none out-in QH9 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGA 2.3 Inactive None out-out out-in VX6 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2A 2.723 Inactive None out-out out-in FVC Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2B 2.723 Inactive None in-none out-in FVC Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2A 2.3 Inactive None in-out out-in HJ9 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2B 2.3 Inactive None in-out out-in HJ9 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HA 2.0 Inactive None in-out out-in P16 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYA 2.891 Inactive None in-out out-in 1N1 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7ZA 2.255 Inactive None in-none out-in 6CI BAL Type1 Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8A 2.9 Inactive None out-none out-in 4B7 Type1.5_Front
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8B 2.9 Inactive None out-none out-in 4B7 Type1.5_Front
TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3HMIA 1.65 Inactive None in-in out-in DKI Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRA 2.4 Inactive BABtrans out-out in-in 1N1 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRB 2.4 Inactive BABtrans out-out in-in 1N1 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXSA 1.89 Inactive BABtrans out-out in-in PP2 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99A 2.001 Inactive BABtrans out-out in-in H88 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99B 2.001 Inactive BABtrans out-out in-in H88 Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZA 2.64 Inactive BABtrans out-out out-in GYL Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZB 2.64 Inactive BABtrans out-out out-in GYL Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7YC9A 1.4 Inactive BABtrans out-out out-in IS4 Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3OCTA 1.95 Inactive BABtrans in-out out-in 1N1 Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6NFIA 2.41 Inactive None out-out none-out KLP Type1
TYR CSK CSK_HUMAN Tyrosine-protein kinase CSK 1BYGA 2.4 Inactive BABtrans out-out none-in STU Type1
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23A 2.58 Inactive None in-out out-in No_ligand No_ligand
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23B 2.58 Inactive None in-out out-in No_ligand No_ligand
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23C 2.58 Inactive None in-out out-in No_ligand No_ligand
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BRJA 2.231 Inactive None in-in out-in VX6 Type1
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BSDA 2.606 Inactive None in-in out-in 1N1 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8H7XB 3.404 Inactive None in-in out-in No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5XGNB 3.0 Inactive None in-in out-in No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 2JITB 3.1 Inactive None in-in out-in No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 2JIUB 3.05 Inactive None in-in in-in No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5PB 3.17 Inactive None in-in out-out No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 3IKAB 2.9 Inactive None in-in out-in No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4WD5B 3.3 Inactive None in-out out-out No_ligand No_ligand
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5UWDA 3.06 Inactive None out-out out-out 8OV Type1
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NA 2.7 Inactive None in-out out-in No_ligand No_ligand
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NB 2.7 Inactive None in-out out-in No_ligand No_ligand
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OA 1.5 Inactive None in-out out-in No_ligand No_ligand
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OB 1.5 Inactive None in-out out-in No_ligand No_ligand
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6AA 2.1 Inactive None in-in none-none AAZ Type1
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6BA 2.1 Inactive None in-in none-none AAX Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBWA 2.65 Inactive None in-in none-out 0PF Type1
TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWA 2.9 Inactive None in-out out-in No_ligand No_ligand
TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4A 2.406 Inactive None in-out out-in No_ligand No_ligand
TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4B 2.406 Inactive None in-in out-in No_ligand No_ligand
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 4MXXB 2.6 Inactive BABtrans out-out none-in DB8 Type1
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRA 2.2 Inactive BABtrans out-out out-out No_ligand No_ligand
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRB 2.2 Inactive BABtrans out-out out-out No_ligand No_ligand

Protein kinases with DFGinter conformation in complex with All ligands

Total number of genes: 51
Total number of chains: 240
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter BABtrans 0 1 0 0 4 0 2 0 18 1 7YC9A
DFGinter None 13 93 0 15 2 0 12 18 57 4 4U3YA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Reso Activity Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UJGA 2.6 Inactive None out-out out-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBA 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBB 2.567 Inactive None out-out none-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBD 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBF 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4A 2.3 Inactive None out-out none-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4B 2.3 Inactive None out-out none-out No_ligand No_ligand
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4YB 7.509 Inactive None in-out in-in No_ligand No_ligand
Corynebacterium glutamicum OTHER PKNG Q8NM29_CORGL non-specific serine/threonine protein kinase 7MXJA 1.92 Inactive None out-out in-in MAP Type1
Corynebacterium glutamicum OTHER PKNG Q8NM29_CORGL non-specific serine/threonine protein kinase 7MXKA 1.99 Inactive None out-out in-in MAP Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QQ7B 2.38 Inactive None none-none none-none SR2 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3LOKB 2.48 Inactive None none-none none-none DJK Type1
Homo sapiens AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJB 2.9 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJD 2.9 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens AGC RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOC 2.75 Inactive None none-none out-out ANP Type1
Homo sapiens AGC RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOG 2.75 Inactive None out-out out-none ANP Type1
Homo sapiens AGC RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 1VZOA 1.8 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76B 3.0 Inactive None none-none out-none ANP Type1
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78A 2.5 Inactive None none-none out-out ANP Type1
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78B 2.5 Inactive None none-none out-out ANP Type1
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A 3.0 Inactive None none-none out-in ANP ANP Type1 Allosteric
Homo sapiens AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 2R5TA 1.9 Inactive None none-none out-out ANP Type1
Homo sapiens AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDMA 2.6 Inactive None none-none out-out MMG Type1
Homo sapiens AGC SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDNA 3.1 Inactive None none-none out-out GMG Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6XKAA 2.65 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVA 2.4 Inactive None out-out out-out ZZL Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVB 2.4 Inactive None out-out out-out ZZL Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVC 2.4 Inactive None out-out out-out ZZL Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2WTVD 2.4 Inactive None out-out out-out ZZL Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5EW9A 2.181 Inactive None out-out out-out 5VC Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6C2RA 1.96 Inactive None out-none out-none EG7 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6C2TA 1.73 Inactive None out-out out-out EGJ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3W16A 2.8 Inactive None out-out out-out P9J Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2J50A 3.0 Inactive None out-out out-out 627 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2J50B 3.0 Inactive None out-out out-out 627 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4C3RA 2.79 Inactive None out-out out-out ACP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTRA 2.85 Inactive None out-out none-out 4RJ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6Z4YA 2.25 Inactive None out-out out-out Q7Q Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6C83B 2.55 Inactive None out-out none-out ACP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6CPGA 2.8 Inactive None out-out none-out 35R Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6CPGD 2.8 Inactive None out-out none-out 35R Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSOA 1.97 Inactive None out-out out-out 627 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSOD 1.97 Inactive None out-out out-none 627 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 1MUOA 2.9 Inactive None out-out none-out ADN Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2J4ZA 2.0 Inactive None out-out out-out 626 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UNZA 2.8 Inactive None out-out out-out 0BZ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UNZB 2.8 Inactive None out-out out-out 0BZ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UO6A 2.8 Inactive None out-out out-out 0BY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UO6B 2.8 Inactive None out-out out-out 0BY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOHA 2.8 Inactive None out-out out-out 0C4 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOHB 2.8 Inactive None out-out out-out 0C4 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOJA 2.9 Inactive None out-out out-out 0C5 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOJB 2.9 Inactive None out-out out-out 0C5 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOKA 2.951 Inactive None out-out out-out 0C6 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOKB 2.951 Inactive None out-out out-out 0C6 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOLA 2.4 Inactive None out-out out-out 0C7 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3UOLB 2.4 Inactive None out-out out-out 0C7 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3FDNA 1.9 Inactive None out-out out-out MMH Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3K5UA 2.35 Inactive None out-out out-out PFQ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4JBQA 2.3 Inactive None out-out out-out VX6 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3LAUA 2.1 Inactive None out-out none-none OFI Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4UZHA 2.0 Inactive None out-out none-none JVE Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3H0YA 2.5 Inactive None out-out none-none 48B Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10A 2.2 Inactive None out-out out-out 97B Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10B 2.2 Inactive None out-out out-out 97B Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3H10D 2.2 Inactive None out-out out-none 97B Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3P9JA 2.8 Inactive None out-out out-out P9J Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3W10A 2.7 Inactive None out-out out-out RO9 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3R22A 2.9 Inactive None out-out out-out D37 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCA 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCB 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCC 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCD 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCE 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2BMCF 2.6 Inactive None out-out out-none MPY Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 7FICA 2.32 Inactive None out-none none-out 5YZ Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 Inactive None out-out none-none ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 Inactive None out-out out-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 Inactive None out-out out-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 9BZGA 1.8 Inactive None out-out out-out OG0 Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 9BZLB 1.81 Inactive None out-out out-out OGR Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8PR7A 2.76 Inactive None out-out none-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTQA 2.8 Inactive None out-out out-out 4RM Type1.5_Back
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4ZTSA 2.9 Inactive None out-out none-none 4RK Type1.5_Back
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3EFWA 2.29 Inactive None out-none none-none AK8 Type1.5_Front
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3EFWB 2.29 Inactive None out-out none-none AK8 Type1.5_Front
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3O50A 2.0 Inactive None out-out none-none LJE Type1.5_Front
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 3O50B 2.0 Inactive None out-out none-out LJE Type1.5_Front
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6HJJA 2.13 Inactive None out-out out-out G7T Type1.5_Front
Homo sapiens CAMK AURKB AURKB_HUMAN Aurora kinase B 4AF3A 2.75 Inactive None out-out none-none VX6 Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FGBA 2.6 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 Inactive None out-out none-none ATP Type1
Homo sapiens CAMK CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 Inactive None out-none none-out ATP Type1
Homo sapiens CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FA 1.97 Inactive None out-out none-none MMW Type1
Homo sapiens CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FB 1.97 Inactive None out-out none-none MMW Type1
Homo sapiens CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T29AAA 1.484 Inactive None out-out none-none M8Z Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4OO 4.8 Inactive None in-none in-in No_ligand No_ligand
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4PH 6.6 Inactive None in-none in-in No_ligand No_ligand
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 3SOAA 3.55 Inactive None in-none in-in DB8 Type1
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4IXPA 2.749 Inactive BABtrans out-none out-out No_ligand No_ligand
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMTA 1.98 Inactive None out-out none-out 47W Type1
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMUA 2.02 Inactive None out-out none-out 0V0 Type1
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDA 2.95 Inactive None out-out out-none No_ligand No_ligand
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDB 2.95 Inactive None out-out out-none No_ligand No_ligand
Homo sapiens CAMK TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEKA 2.8 Inactive None out-none none-none No_ligand No_ligand
Homo sapiens CAMK TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEMA 2.1 Inactive None out-none none-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 Inactive None in-out none-out IRG 0OQ Allosteric Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 Inactive None in-in none-none SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5WJJA 1.6 Inactive None in-in out-out AQY Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6ANLA 2.0 Inactive None in-in none-out T75 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ML5A 1.9 Inactive None in-in none-none 1VI Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HUCA 1.8 Inactive None in-in none-out G97 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 Inactive None in-in none-out SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZSGA 1.89 Inactive None in-in none-out T75 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWTA 1.7 Inactive None in-in out-none GXH Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWUA 2.3 Inactive None in-in none-out GE5 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWVA 1.7 Inactive None in-in none-none GEW Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 Inactive None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
Homo sapiens CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYA 2.52 Inactive None in-out out-out OWQ Type1
Homo sapiens CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYD 2.52 Inactive None out-out out-out OWQ Type1
Homo sapiens CMGC MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCD 2.43 Inactive None out-out out-out OXW Type1
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive BABtrans out-none out-out No_ligand No_ligand
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive BABtrans out-out out-out No_ligand No_ligand
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive BABtrans out-none out-out CK7 Type1
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive BABtrans out-out out-out CK7 Type1
Homo sapiens NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 Inactive None out-none none-out No_ligand No_ligand
Homo sapiens NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 Inactive None out-out out-out AGS Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive BABtrans out-out out-out G41 Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 Inactive None out-out out-out G41 Type1
Homo sapiens OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 8OMVE 4.16 Inactive None in-out out-out No_ligand No_ligand
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5YT3A 2.9 Inactive None out-out none-none ANP Type1
Homo sapiens STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQA 2.3 Inactive BABtrans out-out in-in STU Type1
Homo sapiens STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQB 2.3 Inactive BABtrans in-none in-in STU Type1
Homo sapiens STE MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 9BI8A 2.25 Inactive None out-out out-out A1APL Type1
Homo sapiens STE MAP4K1 M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 9BI8B 2.25 Inactive None out-out out-out A1APL Type1
Homo sapiens STE MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZA 2.09 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens STE MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3YA 1.45 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 9D50B 1.898 Inactive None in-out none-out A1A2T Type1
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFA 1.75 Inactive None out-out out-none 6UI Type1
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFB 1.75 Inactive None out-out out-in 6UI Type1
Homo sapiens STE STK25 STK25_HUMAN Serine/threonine-protein kinase 25 4NZWB 3.583 Inactive None out-out none-in J60 Type1
Homo sapiens STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZFB 3.64 Inactive None out-out out-out DKI Type1
Homo sapiens STE TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88A 2.7 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens STE TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88B 2.7 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 3KMUA 1.8 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 6MIBA 1.8 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 3KMWA 2.0 Inactive None out-out out-out ATP Type1
Homo sapiens TKL ILK ILK_HUMAN Scaffold protein ILK 3REPA 1.8 Inactive None out-out out-out ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 Inactive None out-out out-in ATP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8VH5A 4.0 Inactive None out-out out-in ANP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8VH5C 4.0 Inactive None out-out out-in ANP Type1
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 Inactive None out-out out-in ATP Type1
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3B 2.05 Inactive None out-out out-out No_ligand No_ligand
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3C 2.05 Inactive None out-none none-out No_ligand No_ligand
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3D 2.05 Inactive None out-out none-out No_ligand No_ligand
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XA 2.0 Inactive BABtrans in-out out-in 8DW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XB 2.0 Inactive BABtrans in-out out-in 8DW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYB 2.891 Inactive BABtrans in-out out-in 1N1 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA 2.2 Inactive None in-out out-in STI 1N1 Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC 2.2 Inactive None in-none out-in STI 1N1 Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FA 2.7 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8A 2.5 Inactive None in-out out-in PVB Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8B 2.5 Inactive None in-none out-in PVB Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7SA 1.946 Inactive None in-in out-in 6CI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7SB 1.946 Inactive None in-out out-in 6CI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7ZB 2.255 Inactive None in-in out-in 6CI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YA 2.2 Inactive None in-out out-in 8IW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YB 2.2 Inactive None in-out out-in 8IW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FA 2.45 Inactive None in-none out-in QEW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FB 2.45 Inactive None in-none out-in QEW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HA 2.278 Inactive None in-none out-in QH9 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HB 2.278 Inactive None in-none out-in QH9 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGA 2.3 Inactive None out-out out-in VX6 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2A 2.723 Inactive None out-out out-in FVC Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2B 2.723 Inactive None in-none out-in FVC Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2A 2.3 Inactive None in-out out-in HJ9 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2B 2.3 Inactive None in-out out-in HJ9 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HA 2.0 Inactive None in-out out-in P16 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYA 2.891 Inactive None in-out out-in 1N1 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8I7ZA 2.255 Inactive None in-none out-in 6CI BAL Type1 Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8A 2.9 Inactive None out-none out-in 4B7 Type1.5_Front
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8B 2.9 Inactive None out-none out-in 4B7 Type1.5_Front
Homo sapiens TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3HMIA 1.65 Inactive None in-in out-in DKI Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRA 2.4 Inactive BABtrans out-out in-in 1N1 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRB 2.4 Inactive BABtrans out-out in-in 1N1 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXSA 1.89 Inactive BABtrans out-out in-in PP2 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99A 2.001 Inactive BABtrans out-out in-in H88 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99B 2.001 Inactive BABtrans out-out in-in H88 Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZA 2.64 Inactive BABtrans out-out out-in GYL Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZB 2.64 Inactive BABtrans out-out out-in GYL Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7YC9A 1.4 Inactive BABtrans out-out out-in IS4 Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3OCTA 1.95 Inactive BABtrans in-out out-in 1N1 Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6NFIA 2.41 Inactive None out-out none-out KLP Type1
Homo sapiens TYR CSK CSK_HUMAN Tyrosine-protein kinase CSK 1BYGA 2.4 Inactive BABtrans out-out none-in STU Type1
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23A 2.58 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23B 2.58 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23C 2.58 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BRJA 2.231 Inactive None in-in out-in VX6 Type1
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BSDA 2.606 Inactive None in-in out-in 1N1 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8H7XB 3.404 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5XGNB 3.0 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 2JITB 3.1 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 2JIUB 3.05 Inactive None in-in in-in No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5PB 3.17 Inactive None in-in out-out No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 3IKAB 2.9 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4WD5B 3.3 Inactive None in-out out-out No_ligand No_ligand
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5UWDA 3.06 Inactive None out-out out-out 8OV Type1
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NA 2.7 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NB 2.7 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OA 1.5 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OB 1.5 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6AA 2.1 Inactive None in-in none-none AAZ Type1
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6BA 2.1 Inactive None in-in none-none AAX Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBWA 2.65 Inactive None in-in none-out 0PF Type1
Homo sapiens TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWA 2.9 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4A 2.406 Inactive None in-out out-in No_ligand No_ligand
Homo sapiens TYR ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4B 2.406 Inactive None in-in out-in No_ligand No_ligand
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 4MXXB 2.6 Inactive BABtrans out-out none-in DB8 Type1
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRA 2.2 Inactive BABtrans out-out out-out No_ligand No_ligand
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRB 2.2 Inactive BABtrans out-out out-out No_ligand No_ligand
Mus musculus CAMK AURKA AURKA_MOUSE Aurora kinase A 3DAJA 2.0 Inactive None out-out none-none FXG Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK7A 2.01 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6A 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6B 2.02 Inactive None in-none out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3A 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3B 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FA 2.6 Inactive BABtrans out-out out-none 1N1 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FB 2.6 Inactive BABtrans out-out out-out 1N1 Type1
Rattus norvegicus TYR MUSK MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase 1LUFA 2.05 Inactive None in-in out-in No_ligand No_ligand
Saccharomyces cerevisiae CAMK SNF1 SNF1_YEAST Carbon catabolite-derepressing protein kinase 3MN3A 2.38 Inactive None out-out none-out No_ligand No_ligand
Saccharum officinarum CAMK SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXA 2.0 Inactive None out-out none-none No_ligand No_ligand
Saccharum officinarum CAMK SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXB 2.0 Inactive None out-none none-out No_ligand No_ligand
Schizosaccharomyces pombe CAMK SSP2 SNF1_SCHPO SNF1-like protein kinase ssp2 3H4JB 2.8 Inactive None out-out out-out No_ligand No_ligand

Protein kinases with DFGinter conformation in complex with All ligands

Total number of genes: 11
Total number of chains: 25
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter BABtrans 0 0 0 0 0 0 0 0 2 0 8S9FB
DFGinter None 1 12 0 0 0 0 0 0 8 2 3H4JB
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Reso Activity Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UJGA 2.6 Inactive None out-out out-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBA 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBB 2.567 Inactive None out-out none-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBD 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBF 2.567 Inactive None out-out none-none No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4A 2.3 Inactive None out-out none-out No_ligand No_ligand
Arabidopsis thaliana CAMK SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4B 2.3 Inactive None out-out none-out No_ligand No_ligand
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4YB 7.509 Inactive None in-out in-in No_ligand No_ligand
Corynebacterium glutamicum OTHER PKNG Q8NM29_CORGL non-specific serine/threonine protein kinase 7MXJA 1.92 Inactive None out-out in-in MAP Type1
Corynebacterium glutamicum OTHER PKNG Q8NM29_CORGL non-specific serine/threonine protein kinase 7MXKA 1.99 Inactive None out-out in-in MAP Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QQ7B 2.38 Inactive None none-none none-none SR2 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3LOKB 2.48 Inactive None none-none none-none DJK Type1
Mus musculus CAMK AURKA AURKA_MOUSE Aurora kinase A 3DAJA 2.0 Inactive None out-out none-none FXG Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK7A 2.01 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6A 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6B 2.02 Inactive None in-none out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3A 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3B 2.02 Inactive None in-in out-in SX7 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FA 2.6 Inactive BABtrans out-out out-none 1N1 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FB 2.6 Inactive BABtrans out-out out-out 1N1 Type1
Rattus norvegicus TYR MUSK MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase 1LUFA 2.05 Inactive None in-in out-in No_ligand No_ligand
Saccharomyces cerevisiae CAMK SNF1 SNF1_YEAST Carbon catabolite-derepressing protein kinase 3MN3A 2.38 Inactive None out-out none-out No_ligand No_ligand
Saccharum officinarum CAMK SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXA 2.0 Inactive None out-out none-none No_ligand No_ligand
Saccharum officinarum CAMK SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXB 2.0 Inactive None out-none none-out No_ligand No_ligand
Schizosaccharomyces pombe CAMK SSP2 SNF1_SCHPO SNF1-like protein kinase ssp2 3H4JB 2.8 Inactive None out-out out-out No_ligand No_ligand