PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Group: CMGC
Uniprot: PRP4K_HUMAN
Domain boundary: 687 - 1003


Total number of chains: 22
Spatial Dihedral Chains Representative
DFGin BLAminus 16 AF-Q13523-K1A
DFGout None 1 6CNHA
None None 5 8H6E4Y
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q13523-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 679 - 1007 None None 0
4IANA 2.44 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None X849 0
4IANB 2.44 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None X849 0
6QX9K 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None None 0
8Y6OQ 3.38 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 676 - 1005 None None 0
6PK6A 2.1 Active DFGin BLAminus in-in in-in OND Type1 668 - 1005 None X849 0
4IFCA 2.13 Active DFGin BLAminus in-in in-in ADP Type1 668 - 1005 None X849 0
4IFCB 2.13 Active DFGin BLAminus in-in in-in ADP Type1 670 - 1005 None X849 0
4IIRA 2.0 Active DFGin BLAminus in-in in-in ANP Type1 668 - 1005 None X849 0
4IIRB 2.0 Active DFGin BLAminus in-in in-in ANP Type1 670 - 1005 None X849 0
4IJPA 2.25 Active DFGin BLAminus in-in in-in 1EH Type1 670 - 1005 None X849 0
4IJPB 2.25 Active DFGin BLAminus in-in in-in 1EH Type1 668 - 1005 None X849 0
6PJJA 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 674 - 1005 None X849 0
6PJJB 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 674 - 1005 None X849 0
6PJJC 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 673 - 1005 None X849 0
6PJJD 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 677 - 1005 None X849 3
6CNHA 2.0 Inactive DFGout None in-in none-out 919 Type2 657 - 1005 None None 14
8H6E4Y 3.2 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
8H6J4Y 3.25 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
8QXDK 9.6 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
8R08K 6.1 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
8R0AK 5.8 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0

PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Group: CMGC
Total number of chains: 24
Spatial Dihedral Chains Representative
DFGin BLAminus 16 AF-Q13523-K1A
DFGout None 3 7Q4AB
None None 5 8H6E4Y
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens PRP4K_HUMAN AF-Q13523-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 679 - 1007 None None 0
Homo sapiens PRP4K_HUMAN 4IANA 2.44 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IANB 2.44 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 6QX9K 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 8Y6OQ 3.38 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 6PK6A 2.1 Active DFGin BLAminus in-in in-in OND Type1 668 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IFCA 2.13 Active DFGin BLAminus in-in in-in ADP Type1 668 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IFCB 2.13 Active DFGin BLAminus in-in in-in ADP Type1 670 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IIRA 2.0 Active DFGin BLAminus in-in in-in ANP Type1 668 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IIRB 2.0 Active DFGin BLAminus in-in in-in ANP Type1 670 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IJPA 2.25 Active DFGin BLAminus in-in in-in 1EH Type1 670 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 4IJPB 2.25 Active DFGin BLAminus in-in in-in 1EH Type1 668 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 6PJJA 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 674 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 6PJJB 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 674 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 6PJJC 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 673 - 1005 None X849 0
Homo sapiens PRP4K_HUMAN 6PJJD 2.4 Active DFGin BLAminus in-in in-in OCJ Type1 677 - 1005 None X849 3
Homo sapiens PRP4K_HUMAN 6CNHA 2.0 Inactive DFGout None in-in none-out 919 Type2 657 - 1005 None None 14
Homo sapiens PRP4K_HUMAN 8H6E4Y 3.2 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 8H6J4Y 3.25 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 8QXDK 9.6 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 8R08K 6.1 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
Homo sapiens PRP4K_HUMAN 8R0AK 5.8 Inactive None None in-none in-in No_ligand No_ligand 676 - 1005 None None 0
Toxoplasma gondii S7UT92_TOXGG 7Q4AA 2.31 Inactive DFGout None in-in out-out A9I Type2 547 - 894 None X729 0
Toxoplasma gondii S7UT92_TOXGG 7Q4AB 2.31 Inactive DFGout None in-out out-out A9I Type2 546 - 891 None X729 0

PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Group: CMGC
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGout None 2 7Q4AB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Toxoplasma gondii S7UT92_TOXGG 7Q4AA 2.31 Inactive DFGout None in-in out-out A9I Type2 547 - 894 None X729 0
Toxoplasma gondii S7UT92_TOXGG 7Q4AB 2.31 Inactive DFGout None in-out out-out A9I Type2 546 - 891 None X729 0