CMGC_PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Total number of chains: 23
Active chains: 1
Uniprot: PRP4K_HUMAN
Kinase Domain Residues: 687 - 1003
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 17 73.9% AF-Q13523-K3A
None None 5 21.7% 8H6E4Y
DFGout None 1 4.3% 6CNHA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13523-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 679 - 1007 0 None None Serine/threonine-protein kinase PRP4 homolog
4IFCA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IFCB 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IIRA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IIRB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
AF-Q13523-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 679 - 1007 0 None None Serine/threonine-protein kinase PRP4 homolog
4IANA 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IANB 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6QX9K 3.28 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8Y6OQ 3.38 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
6PK6A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi OND Type1 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IJPA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 1EH Type1 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
4IJPB 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 1EH Type1 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6PJJA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 674 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6PJJB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 674 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6PJJC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 673 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6PJJD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi OCJ Type1 677 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog
6CNHA 2.0 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 919 Type2 657 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8H6E4Y 3.2 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8H6J4Y 3.25 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8QXDK 9.6 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8R08K 6.1 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog
8R0AK 5.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog

CMGC_PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Total number of chains: 25
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 17 68.0% AF-Q13523-K3A
None None 5 20.0% 8H6E4Y
DFGout None 3 12.0% 7Q4AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PRP4K_HUMAN AF-Q13523-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 679 - 1007 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IFCA 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IFCB 2.13 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ADP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IIRA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IIRB 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi ANP ATPlike 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN AF-Q13523-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 679 - 1007 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IANA 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IANB 2.44 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6QX9K 3.28 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8Y6OQ 3.38 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6PK6A 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi OND Type1 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IJPA 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 1EH Type1 670 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 4IJPB 2.25 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 1EH Type1 668 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6PJJA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 674 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6PJJB 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 674 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6PJJC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii OCJ Type1 673 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6PJJD 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi OCJ Type1 677 - 1005 0 PTR849 None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 6CNHA 2.0 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 919 Type2 657 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8H6E4Y 3.2 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8H6J4Y 3.25 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8QXDK 9.6 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8R08K 6.1 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
PRP4K_HUMAN 8R0AK 5.8 Inactive None‑None in-none in-out nonTYR APEdihe_aaini APEdist_oioi No_ligand No_ligand 676 - 1005 0 None None Serine/threonine-protein kinase PRP4 homolog Homo sapiens
S7UT92_TOXGG 7Q4AA 2.31 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaoii APEdist_oooo A9I Type2 547 - 894 0 PTR729 None non-specific serine/threonine protein kinase Toxoplasma gondii
S7UT92_TOXGG 7Q4AB 2.31 Inactive DFGout‑None in-out out-out nonTYR APEdihe_aaoii APEdist_oioo A9I Type2 546 - 891 0 PTR729 None non-specific serine/threonine protein kinase Toxoplasma gondii

CMGC_PRP4K (Serine/threonine-protein kinase PRP4 homolog)

Total number of chains: 2
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 7Q4AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
S7UT92_TOXGG 7Q4AA 2.31 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaoii APEdist_oooo A9I Type2 547 - 894 0 PTR729 None non-specific serine/threonine protein kinase Toxoplasma gondii
S7UT92_TOXGG 7Q4AB 2.31 Inactive DFGout‑None in-out out-out nonTYR APEdihe_aaoii APEdist_oioo A9I Type2 546 - 891 0 PTR729 None non-specific serine/threonine protein kinase Toxoplasma gondii