AGC_GRK6 (G protein-coupled receptor kinase 6)

Total number of chains: 8
Active chains: 8
Uniprot: GRK6_HUMAN
Kinase Domain Residues: 186 - 448
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P43250-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
AF-P43250-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 178 - 456 0 None None G protein-coupled receptor kinase 6
AF-P43250-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 178 - 456 0 None None G protein-coupled receptor kinase 6
3NYNA 2.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 2 - 557 0 None None G protein-coupled receptor kinase 6
3NYNB 2.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 2 - 557 0 None None G protein-coupled receptor kinase 6

AGC_GRK6 (G protein-coupled receptor kinase 6)

Total number of chains: 8
Active chains: 8
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P43250-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
GRK6_HUMAN 2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN 2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN 3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN 3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN AF-P43250-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 178 - 456 0 None None G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN AF-P43250-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 178 - 456 0 None None G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN 3NYNA 2.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
GRK6_HUMAN 3NYNB 2.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SGV Type1 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens

AGC_GRK6 (G protein-coupled receptor kinase 6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism