CAMK_DAPK2 (Death-associated protein kinase 2)

Total number of chains: 41
Active chains: 32
Uniprot: DAPK2_HUMAN
Kinase Domain Residues: 23 - 285
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 41 100.0% AF-Q9UIK4-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9UIK4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 293 0 None None Death-associated protein kinase 2
AF-Q9UIK4-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 293 0 None None Death-associated protein kinase 2
1ZWSA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSE 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSF 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSG 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1ZWSH 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2
1Z9XA 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
1Z9XB 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
1Z9XC 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A2AA 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 314 0 None None Death-associated protein kinase 2
2A2AB 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2
2A2AC 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2
2A2AD 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2
2A27A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2
2A27B 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A27C 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A27D 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2
2A27E 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A27F 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A27G 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2
2A27H 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2
6PAWA 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 329 0 None S318A Death-associated protein kinase 2
6PAWB 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 329 0 None S318A Death-associated protein kinase 2
6PAWE 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 318 0 None S318A Death-associated protein kinase 2
2CKEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 11 - 311 0 None None Death-associated protein kinase 2
2CKEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2
2CKEC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2
2CKED 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2
1WMKA 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2
1WMKB 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 325 0 None S318D Death-associated protein kinase 2
1WMKC 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2
1WMKD 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 325 0 None S318D Death-associated protein kinase 2
1WMKE 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 324 0 None S318D Death-associated protein kinase 2
1WMKF 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2
1WMKG 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 324 0 None S318D Death-associated protein kinase 2
1WMKH 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 315 0 None S318D Death-associated protein kinase 2
6PAWF 2.953 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 14 - 327 0 None S318A Death-associated protein kinase 2

CAMK_DAPK2 (Death-associated protein kinase 2)

Total number of chains: 47
Active chains: 36
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 47 100.0% AF-Q9UIK4-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DAPK2_HUMAN AF-Q9UIK4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 293 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN AF-Q9UIK4-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 293 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSE 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSF 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSG 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1ZWSH 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 289 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1Z9XA 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1Z9XB 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1Z9XC 3.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A2AA 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 11 - 314 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A2AB 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A2AC 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A2AD 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27A 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27B 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27C 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27D 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27E 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27F 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27G 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 314 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2A27H 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 315 0 None W315S,S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 6PAWA 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 329 0 None S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 6PAWB 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 329 0 None S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 6PAWE 2.953 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 14 - 318 0 None S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2CKEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 11 - 311 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2CKEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2CKEC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 2CKED 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQU Type1 12 - 311 0 None None Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKA 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKB 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 325 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKC 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKD 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 325 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKE 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 324 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKF 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 314 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKG 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 324 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 1WMKH 3.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iiio No_ligand No_ligand 12 - 315 0 None S318D Death-associated protein kinase 2 Homo sapiens
DAPK2_HUMAN 6PAWF 2.953 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 14 - 327 0 None S318A Death-associated protein kinase 2 Homo sapiens
DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YA9A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D1D Allosteric 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YA9B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D1D Allosteric 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YABB 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus

CAMK_DAPK2 (Death-associated protein kinase 2)

Total number of chains: 6
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 2YABA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YA9A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D1D Allosteric 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YA9B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D1D Allosteric 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
DAPK2_MOUSE 2YABB 1.9 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus