DAPK2 (Death-associated protein kinase 2)

Group: CAMK
Uniprot: DAPK2_HUMAN
Domain boundary: 23 - 285


Total number of chains: 40
Spatial Dihedral Chains Representative
DFGin BLAminus 40 AF-Q9UIK4-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q9UIK4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 293 None None 0
1ZWSA 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSB 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSC 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSD 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSE 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSF 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSG 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1ZWSH 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
1Z9XA 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
1Z9XB 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
1Z9XC 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A2AA 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 11 - 314 None None 0
2A2AB 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
2A2AC 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
2A2AD 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
2A27A 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
2A27B 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A27C 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A27D 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
2A27E 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A27F 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A27G 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
2A27H 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
1WMKA 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
1WMKB 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 325 S318D None 0
1WMKC 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
1WMKD 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 325 S318D None 0
1WMKE 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 324 S318D None 0
1WMKF 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
1WMKG 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 324 S318D None 0
1WMKH 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 315 S318D None 0
6PAWA 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 329 S318A None 0
6PAWB 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 329 S318A None 0
6PAWE 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 318 S318A None 0
6PAWF 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 327 S318A None 0
2CKEA 2.8 Active DFGin BLAminus in-in in-in IQU Type1 11 - 311 None None 0
2CKEB 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0
2CKEC 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0
2CKED 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0

DAPK2 (Death-associated protein kinase 2)

Group: CAMK
Total number of chains: 46
Spatial Dihedral Chains Representative
DFGin BLAminus 46 AF-Q9UIK4-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens DAPK2_HUMAN AF-Q9UIK4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 293 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSA 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSB 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSC 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSD 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSE 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSF 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSG 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1ZWSH 2.9 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 289 None None 0
Homo sapiens DAPK2_HUMAN 1Z9XA 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 1Z9XB 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 1Z9XC 3.93 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A2AA 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 11 - 314 None None 0
Homo sapiens DAPK2_HUMAN 2A2AB 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
Homo sapiens DAPK2_HUMAN 2A2AC 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
Homo sapiens DAPK2_HUMAN 2A2AD 1.47 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 None None 0
Homo sapiens DAPK2_HUMAN 2A27A 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27B 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27C 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27D 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27E 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27F 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27G 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 314 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 2A27H 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 12 - 315 W315S,S318A None 0
Homo sapiens DAPK2_HUMAN 1WMKA 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKB 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 325 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKC 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKD 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 325 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKE 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 324 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKF 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 314 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKG 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 324 S318D None 0
Homo sapiens DAPK2_HUMAN 1WMKH 3.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 12 - 315 S318D None 0
Homo sapiens DAPK2_HUMAN 6PAWA 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 329 S318A None 0
Homo sapiens DAPK2_HUMAN 6PAWB 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 329 S318A None 0
Homo sapiens DAPK2_HUMAN 6PAWE 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 318 S318A None 0
Homo sapiens DAPK2_HUMAN 6PAWF 2.953 Active DFGin BLAminus in-in in-in No_ligand No_ligand 14 - 327 S318A None 0
Homo sapiens DAPK2_HUMAN 2CKEA 2.8 Active DFGin BLAminus in-in in-in IQU Type1 11 - 311 None None 0
Homo sapiens DAPK2_HUMAN 2CKEB 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0
Homo sapiens DAPK2_HUMAN 2CKEC 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0
Homo sapiens DAPK2_HUMAN 2CKED 2.8 Active DFGin BLAminus in-in in-in IQU Type1 12 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YA9A 2.3 Active DFGin BLAminus in-in in-in D1D Allosteric 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YA9B 2.3 Active DFGin BLAminus in-in in-in D1D Allosteric 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YAAA 2.3 Active DFGin BLAminus in-in in-in ATP Type1 12 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin BLAminus out-out in-in ATP Type1 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YABA 1.9 Active DFGin BLAminus in-in in-in AMP Type1 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YABB 1.9 Inactive DFGin BLAminus in-out in-in AMP Type1 13 - 311 None None 0

DAPK2 (Death-associated protein kinase 2)

Group: CAMK
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 6 2YABA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Mus musculus DAPK2_MOUSE 2YA9A 2.3 Active DFGin BLAminus in-in in-in D1D Allosteric 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YA9B 2.3 Active DFGin BLAminus in-in in-in D1D Allosteric 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YAAA 2.3 Active DFGin BLAminus in-in in-in ATP Type1 12 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YAAB 2.3 Inactive DFGin BLAminus out-out in-in ATP Type1 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YABA 1.9 Active DFGin BLAminus in-in in-in AMP Type1 13 - 311 None None 0
Mus musculus DAPK2_MOUSE 2YABB 1.9 Inactive DFGin BLAminus in-out in-in AMP Type1 13 - 311 None None 0